KOMORI Hiroaki 小森浩章

Researcher Number	30372725
External Links
Affiliation (based on the past Project Information) *help	2008: 愛媛大学, 大学院・医学系研究科, 講師 2007: Ehime University, Graduate School of Medicine, Assistant Professor 2006: 愛媛大学, 大学院医学系研究科, 助手 2004 – 2005: 愛媛大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Applied genomics Except Principal Investigator Experimental pathology / Kidney internal medicine
Keywords	Principal Investigator lprマウス / 環境化学物質 / アレルギー / ゲノム解析 / 組換え近交系マウス / 砒素 / 組換え近交系MXH / アポトーシス / 免疫毒性 / 無細胞蛋白質合成系 … More / AlphaScreen法 / 自己抗体 / 自己免疫疾患 / 疾患モデル動物 / 組み換え近交系 / 膠原病 / 無細胞タンパク質合成系 / 疾患モデル / MRL / 組換え近交系 / genomics … More Except Principal Investigator MRL / 糸球体腎炎 / 血管炎 / 1pr / TLR3 / ループス / 唾液腺炎 / 涙腺炎 / 細胞移入 / GFP / gldマウス / Fas ligand / lpr / MSM / Ms / QTL解析 / 位置的候補遺伝子 / Cd59a / プロモーター多型 / リコンビナントコンジェニックマウス / MRL/lpr / MSM/Ms / リコンビナント温ジェニックマウス / 系球体腎炎 / 抗Cd59a抗体 / CD59 / ルチフェラーゼアッセイ / 膠原病 / 組換え近交系 / SDP表 / 自己抗体 / 無細胞系タンパク質合成 / AlphaScreen法 / 炎症性サイトカイン / SNPs / 環境要因 / poly I:C / ポリジーン / MXH / collagen disease / recombinant inbred strain / SDP table / autoantibody / protein synthesis in cell free system / AlphaScreen method / inflammatory cytokines Less

Resistance genes to collagen disease in a wild mice-derived inbred strain MSM/Ms
- Principal Investigator
  
  NOSE Masato
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Ehime University
プロテオームを基盤とする膠原病関連新規自己抗体の同定・解析法の確立Principal Investigator
- Principal Investigator
  
  小森浩章
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied genomics
- Research Institution
  Ehime University
Establishment of a novel recombinant inbred strain of mice MXH/lpr with genetic dissociation of the complex pathological and pathophysiological phenotypes of collagen disease under a polygene network
- Principal Investigator
  
  NOSE Masato
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Ehime University
GFPマウスによる細胞移入系を用いたループス病変発症機序の解析
- Principal Investigator
  
  能勢眞人 (能勢真人)
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Ehime University
環境化学物質のアレルギー誘発機構のゲノム解析Principal Investigator
- Principal Investigator
  
  小森浩章
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Ehime University

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book

[Book] AnnualReview免疫20062005
- Author(s)
  能勢眞人, 小森浩章
- Total Pages
  246
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-16651025
[Journal Article] Role of SLAM-associated protein in the pathogenesis of autoimmune diseases and immunological disorders2010
- Author(s)
  Furukawa H, Tohma, S Kitazawa H, Komori H, Nose M, Ono M.
- Journal Title
  
  Arch Immunol Ther Exp 58
  
  Pages: 37-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system2010
- Author(s)
  Tanaka Y, Komori H, Mori S, Soga Y, Tsubaki T, Terada M, Miyazaki T, Fujino T, Nakamura S, Kanno H, Sawasaki T, Endo Y, Nose M.
- Journal Title
  
  Tohoku J Exp Med 220
  
  Pages: 199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat Cell-Free synthesis.2010
- Author(s)
  Matsuoka K, Komori H, Nose M, Endo Y, Sawasaki T.
- Journal Title
  
  J Proteome Res.
  
  Volume: 9 Pages: 4264-4273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system.2010
- Author(s)
  Tanaka Y, Komori H, Mori S, Soga Y, Tsubaki T, Terada M, Miyazaki T, Fujino T, Nakamura S, Kanno H, Sawasaki T, Endo Y, Nose M.
- Journal Title
  
  Tohoku J Exp Med. 220
  
  Pages: 199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system.2010
- Author(s)
  Tanaka Y, Komori H, Mori S, Soga Y, Tsubaki T, Terada M, Miyazaki T, Fujino T, Nakamura S, Kanno H, Sawasaki T, Endo Y, Nose M.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume: 220 Pages: 199-206
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat Cell-Free synthesis.2010
- Author(s)
  Matsuoka K, Komori H, Nose M, Endo Y, Sawasaki T.
- Journal Title
  
  J Proteome Res. 9
  
  Pages: 4264-4273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity.2009
- Author(s)
  Soga Y, Komori H, Nose M, et al
- Journal Title
  
  Tohoku J. Exp. Med 217
  
  Pages: 175-184
- NAID
  10025105148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Genetic dissociation of dacryoadenitis and sialadenitis in a sjogren's syndrome mouse model with common and different susceptibility gene loci.2009
- Author(s)
  Kamao T, Miyazaki T, Soga Y, Komori H, Terada M, Ohashi Y, Nose M.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 50
  
  Pages: 3257-3265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity.2009
- Author(s)
  Soga Y, Komori H, Miyazaki T, Arita N, Terada M, Kamada K, Tanaka Y, Fujino T, Hiasa Y, Matsuura B, Onji M, Nose M.
- Journal Title
  
  Tohoku J Exp Med. 217(3)
  
  Pages: 175-184
- NAID
  10025105148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytoxicity2009
- Author(s)
  Soga Y, Komori H, Miyazaki T, Arita N, Terada M, Kamada K, Tanaka Y, Fujino T, Hiasa Y, Matsuura B, Onji M, Nose M.
- Journal Title
  
  Tohoku J.Exp. Med. 217
  
  Pages: 175-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Genetic dissociation of dacryoadenitis and sialadenitis in a sjogren's syndrome mouse model with common and different susceptibility gene loci2009
- Author(s)
  Kamao T, Miyazaki T, Soga Y, Komori H, Terada M, Ohashi Y, Nose M.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 50
  
  Pages: 3257-3265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] 血管炎発症のポリジーンネットワークモデル2009
- Author(s)
  能勢眞人, 小森浩章
- Journal Title
  
  リウマチ科 42
  
  Pages: 337-343
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] モデルマウスから学ぶ血管炎のゲノム的仕組み2009
- Author(s)
  能勢眞人, 小森浩章
- Journal Title
  
  J Jpm Coll Angiol 49
  
  Pages: 11-16
- NAID
  10025626686
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] Novel recombinant congenic mouse strain developing arthritis with enthesopathy.2008
- Author(s)
  Mori S, Tanda N, Ito R.M, Oishi H, Tsubaki T, Komori H, Zhang MC, Ono M, Nishimura M, Nose M.
- Journal Title
  
  Pathology Int. 58
  
  Pages: 407-414
- NAID
  10027377068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390112
[Journal Article] A novel recombinant congenic mouse strain developing arthritis with enthesopathy2008
- Author(s)
  Mori, S, Tanda, N, Ito, M, Oishi, H, Tsubaki, T, Komori, H, Zhang, M, Ono, M, Nishimura, M, Nose, M
- Journal Title
  
  Pathology Int (in press)
- NAID
  10027377068
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Journal Article] 膠原病のゲノム解析に基づく疾病関連タンパク質の探索 : 無細胞タンパク質合成系の応用.2007
- Author(s)
  能勢眞人, 小森浩章, 宮崎龍彦, 澤崎達也, 遠藤弥重太
- Journal Title
  
  生化学 79
  
  Pages: 287-295
- Data Source
  KAKENHI-PROJECT-17659258
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneousautoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice2006
- Author(s)
  Komori H, Furukawa H, Nose M, et. al.
- Journal Title
  
  J Immunol 176(1)
  
  Pages: 395-400
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390123
[Journal Article] A signal adaptor SIAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice2006
- Author(s)
  Komori, H, Furukawa, H, Mori, S, Ita, MR, Terada, M, Zhang, MC, Ishii, N, Sakuma, N, Nose M, Ono, M
- Journal Title
  
  J Immunol 176(1)
  
  Pages: 395-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Journal Article] Cappuccino mutation in an autoimmune-prone strain of mice suggests a role of platelet function in the progression of immune complex crescentic glomerulonephritis.2006
- Author(s)
  Yoshida M, Saiga K, Hato T, Iwaki S, Niiya T, Arita N, Komori H, Tsubaki T, Furukawa H, Terada M, Maeyama K, Nemoto K, Nose M, Ono M.
- Journal Title
  
  Arthritis Rheum
  
  Pages: 2934-2943
- Data Source
  KAKENHI-PROJECT-18651097
[Journal Article] An epistatic effect of the female specific loci on the development of autoimmune vasculitis and antinuclear autoantibody in murine lupus.2006
- Author(s)
  Zhang MC, Misu N, Furukawa H, Watanabe Y, Terada M, Komori H, Miyazaki T, Nose M, Ono M.
- Journal Title
  
  Ann Rheum Dis 65
  
  Pages: 495-500
- Data Source
  KAKENHI-PROJECT-18651097
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslprlupus mice.2006
- Author(s)
  Komori H, Furukawa H, Mori S, Ito MR, Terada M, Zhang MC, Ishii N, Sakuma N, Nose M, Ono M.
- Journal Title
  
  J Immunol 176
  
  Pages: 395-400
- Data Source
  KAKENHI-PROJECT-18651097
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice.2006
- Author(s)
  Komori H, Furukawa H, Nose M, et al.
- Journal Title
  
  J Immunol 176
  
  Pages: 395-400
- Data Source
  KAKENHI-PROJECT-17659258
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice.2006
- Author(s)
  Komori H, Furukawa H, Nose M et al.
- Journal Title
  
  J Immunol 176
  
  Pages: 395-400
- Data Source
  KAKENHI-PROJECT-18390123
[Journal Article] Cappuccino mutation in an autoimmune-prone strain of mice suggests a role of platelet function in the progression of immune complex crescentic glomerulonephritis2006
- Author(s)
  Yoshida, M, Saiga, K, Hato, T, Iwaki, S, Niiya, T, Arita, N, Komori, H, Tsubaki, T, Furukawa, H, Terada, M, Maeyama, K, Nemoto, K, Nose, M, Ono, M
- Journal Title
  
  Arthritis Rheum 54(9)
  
  Pages: 2934-2943
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Journal Article] An eplstatic effect of the female specific loci on the development of autoimmune vasculitis and antinuclear autoantibody in murine lupus2006
- Author(s)
  Zhang MC, Komori H et al.
- Journal Title
  
  Annals of the rheumatic diseases 65(4)
  
  Pages: 495-500
- Data Source
  KAKENHI-PROJECT-16651025
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Fas^<lpr> lupus mice.2006
- Author(s)
  Komori H, et al.
- Journal Title
  
  Journal of Immunology 176(1)
  
  Pages: 395-400
- Data Source
  KAKENHI-PROJECT-16651025
[Journal Article] A signal adaptor SLAM-associated protein regulates spontaneous autoimmunity and Fas-dependent lymphoproliferation in MRL-Faslpr lupus mice.2006
- Author(s)
  Komori H, Nose M, et al.
- Journal Title
  
  J Immunol 176
  
  Pages: 395-400
- Data Source
  KAKENHI-PROJECT-17659258
[Journal Article] An epistatic effect of the female specific loci on the development of autoimmune vasculitis and antinuclear autoantibody in murine lupus2006
- Author(s)
  Zhang, MC, Misu, N, Furukawa, H, Watanabe, Y, Terada, M, Komori, H, Mivazaki, T, Nose, M, Ono, M
- Journal Title
  
  Ann Rheum Dis 65(4)
  
  Pages: 495-500
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Presentation] Common and different gene loci susceptible to sialoadenitis and dacryoadenitis in a sjogen's syndrome mouse model.2010
- Author(s)
  Kamao T, Miyazaki T, Soga Y, Komori H, Terada M, Nose M
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  Kobe, Japan.
- Data Source
  KAKENHI-PROJECT-20390112
[Presentation] Common and different gene loci susceptible to sialoadenitis and dacryoadenitis in a sjogren's syndrome mouse model.2008
- Author(s)
  Kamao T, Miyazaki T, Soga Y, Komori H, Terada M, Nose M
- Organizer
  6th International Congress on Autoimmunity
- Place of Presentation
  Porto, Portugal.
- Data Source
  KAKENHI-PROJECT-20390112
[Presentation] Genetic basis of autoimmune pancreatitis induced by the stimulation through the toll-like receptor 3 signaling.2008
- Author(s)
  Soga Y, Komori H, Terada T, Miyazaki T, Nose M
- Organizer
  6th International Congress on Autoimmunity
- Place of Presentation
  Porto, Portugal.
- Data Source
  KAKENHI-PROJECT-20390112
[Presentation] 自然免疫系刺激により誘導される自己免疫性膵炎の疾患感受性遺伝子解析2008
- Author(s)
  小森浩章、曽我美子、能勢眞人
- Organizer
  第97回日本病理学会総会(日本病理学会会誌第97巻第1号p169.)
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-20390112
[Presentation] Genetic basis of autoimmnune pancreatitis induced by the stimulation through the toll-like receptor 3 signaling.2008
- Author(s)
  Soga Y, Komori H, Nose M, et al
- Organizer
  6^<th> Intemational Congress on Autoimmunity
- Place of Presentation
  Porto, Portugal.
- Data Source
  KAKENHI-PROJECT-20390112
[Presentation] A novel arthritis model causing ankylosis derived from a recombinant congenic mouse strain between MRL/Ipr and C3H/Ipr crosses2006
- Author(s)
  Mori, S., Tanda, N., Ito, MR., Tsubaki, T., Komori, H., Oishi, H., Zhang, MC., Ono, M., Nishimura, M., Nose, M
- Organizer
  5th International Congress on Autoimmunity
- Place of Presentation
  Sorrento, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Presentation] Autoantibody-proteomics in autoimmune disease-prone recombinantinbred strains of mice using a novel high-throughput detectionsystem2006
- Author(s)
  Komori H, Soga Y, Sawasaki T, Endo Y, Nose M.
- Organizer
  5th International Congress on Autoimmunity
- Place of Presentation
  イタリア,ソレント
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390123
[Presentation] Autoantibody-proteomics in autoinunune disease-prone recombinant inbred strains of mice using a novel high-throughput detection system2006
- Author(s)
  Komori, H., Soga, Y., Sawasaki, T., Endo, Y., Nose, M
- Organizer
  5th International Congress on Autoimmunity
- Place of Presentation
  Sorrento, Italy
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390123

1. NOSE Masato (70030913)

# of Collaborated Projects: 4 results

# of Collaborated Products: 32 results
2. MIYAZAKI Tatsuhiko (80239384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. SOGA Yoshiko (10549182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
4. ONO Masao (20302218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 岩崎美津子 (00335902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOMORI Hiroaki 小森 浩章

Research Projects

Research Products

Co-Researchers

Resistance genes to collagen disease in a wild mice-derived inbred strain MSM/Ms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プロテオームを基盤とする膠原病関連新規自己抗体の同定・解析法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of a novel recombinant inbred strain of mice MXH/lpr with genetic dissociation of the complex pathological and pathophysiological phenotypes of collagen disease under a polygene network

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

GFPマウスによる細胞移入系を用いたループス病変発症機序の解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

環境化学物質のアレルギー誘発機構のゲノム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] AnnualReview免疫20062005

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Role of SLAM-associated protein in the pathogenesis of autoimmune diseases and immunological disorders2010

Author(s)

Journal Title

Data Source

[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system2010

Author(s)

Journal Title

Data Source

[Journal Article] Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat Cell-Free synthesis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system.2010

Author(s)

Journal Title

Data Source

[Journal Article] Evaluating the role of rheumatoid factors in the development of rheumatoidarthritis in a mouse model with a newly established ELISA system.2010

Author(s)

Journal Title

Data Source

[Journal Article] Simple screening method for autoantigen proteins using the N-terminal biotinylated protein library produced by wheat Cell-Free synthesis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Genetic dissociation of dacryoadenitis and sialadenitis in a sjogren's syndrome mouse model with common and different susceptibility gene loci.2009

Author(s)

Journal Title

Data Source

[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytotoxicity.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Toll-Like receptor 3 signaling induces chronic pancreatitis through the Fas/Fas ligand-mediated cytoxicity2009

Author(s)

Journal Title

KOMORI Hiroaki 小森浩章