KAGAMI Shin-ichiro 加々美新一郎

Researcher Number	30375654
Affiliation (based on the past Project Information) *help	2011: 千葉大学, 医学部附属病院, 助教 2011: 千葉大学, 医学部附属病院, 講師 2007 – 2010: Chiba University, Graduate School of Medicine, Chiba University Department of Molecular Genetics, Assistant Professor 2006: Chiba University, Molecular Genetics, Assistant Professor, 大学院医学研究院, 助手 2005: 千葉大学, 大学院・医学研究院, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / アレルギー Except Principal Investigator Biological Sciences / Respiratory organ internal medicine / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator Stat5a / ChIP / ICOS / 肺内胚中心様組織 / IL-21 / TFH細胞様細胞 / BTLA / IgE / IgG4関連疾患 / 喘息 … More / T_<FH>細胞 / CXCR5 / Th17細胞 / Wnt/カテニン / SGK1 / 関節リウマチ / Wnt/βカテニン / Th2細胞 / T細胞依存的B細胞応答 / TFH細胞 / mastermind like 2 / Notch receptor / クロマチン免疫沈降 / Th2 Cells / T cell dependent B cell responses / T_<FH> Cells … More Except Principal Investigator T-bet / アレルギー性炎症 / 気管支喘息 / IL-21 / Th17細胞 / Tfh細胞 / IL-4 / IFN-γ / Stat6 / Stat4 / 免疫監視機構 / 好酸球 / 好中球 / IL-17 / 免疫監視 / IL-6 / master regulator / 自己免疫疾患 / BTLA / master relator / 喘息 / IL-22 / c-Maf / T細胞 / 免疫療法 / cMaf / 気道上皮細胞 / STAT6 / 形質細胞様樹状細胞 / Th2細胞抑制 / 樹状細胞 / plasmacytoid dendritic cells / Th2 cell suppression Less

関節リウマチのTh17細胞分化におけるWnt/カテニン-SGK1経路の役割の解明Principal Investigator
- Principal Investigator
  
  加々美新一郎
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Chiba University
Analysis of helper T cell subset in severe asthma for the development of new immunotherapy
- Principal Investigator
  
  NAKAJIMA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Chiba University
新規ヘルパーT細胞分画IL-21産生T細胞の自己免疫疾患における役割の解明
- Principal Investigator
  
  中島裕史
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Analysis of regulation of antigen-specific IgE production in BALTPrincipal Investigator
- Principal Investigator
  
  KAGAMI Shin-ichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Chiba University
Comprehensive Analysis of Stat5a Target Genes in Th2 Cell DifferentiationPrincipal Investigator
- Principal Investigator
  
  KAGAMI Shin-ichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  アレルギー
- Research Institution
  Chiba University
アレルギー性気道炎症の対する免疫監視機構の解明
- Principal Investigator
  
  NAKAJIMA Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Mechanisms underlying IL-4-induced IFN-γ production in plasmacytoid dendritic cells
- Principal Investigator
  
  NAKAJIMA Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Chiba University

All 2012 2011 2010 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] 臨床・アレルギー科(ゲラニルゲラニル化阻害によるTh17細胞/Treg細胞バランスの制御)2009
- Author(s)
  加々美新一郎、金成博子、中島裕史
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Roles of CRTH2+ CD4+ T Cells in Immunoglobulin G4-Related Lacrimal Gland Enlargement2012
- Author(s)
  Saito Y, Kagami S, Kawashima S, Takahashi K, Ikeda K, Hirose K, Oshitari T, Yamamoto S, Okamoto Y, Nakajima H
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 158 Suppl 1 Pages: 42-46
- DOI
  10.1159/000337761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591113, KAKENHI-PROJECT-23591433, KAKENHI-PROJECT-23659496, KAKENHI-PROJECT-24591441
[Journal Article] Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas- independent liver injury in MRL- lpr/lpr mice2011
- Author(s)
  Oya Y, Watanabe N, Owada T, Oki M, Ikeda K, Suto A, Kagami S-I, Hirose K, Kishimoto T, Nakajima H
- Journal Title
  
  Int. Immunol.
  
  Volume: 23 Pages: 335-344
- DOI
  10.1093/intimm/dxr017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255, KAKENHI-PROJECT-21591263, KAKENHI-PUBLICLY-22021009, KAKENHI-PROJECT-22790748, KAKENHI-PROJECT-23591113, KAKENHI-PROJECT-23591432, KAKENHI-PROJECT-23591433
[Journal Article] Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.2010
- Author(s)
  Iwata A, Watanabe N, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J Immunol
  
  Volume: 184 Pages: 127-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.2010
- Author(s)
  Iwata A, Watanabe N, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J Immunol. 184
  
  Pages: 127-133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immne responses.2010
- Author(s)
  Kashiwakuma D, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J Immunol. 185
  
  Pages: 2730-2736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Protective roles of B and T lymphocyte attenuator (BTLA) in NKT cell-mediated experimental hepatitis2010
- Author(s)
  Iwata A, Watanabe N, Oya Y, Owada T, Ikeda K, Suto A, Kagami S, Hirose K, Kanari H, Kawashima S, Nakayama T, Taniguchi M, Iwamoto I, Nakajima H
- Journal Title
  
  J. Immunol
  
  Volume: 184 Pages: 127-133
- DOI
  10.4049/jimmunol.0900389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255
[Journal Article] c-Maf activates the promoter and enhancer of IL-21 gene while TGF-β inhibits c-Maf-induced IL-21expression in CD4^+ T cells2010
- Author(s)
  Hiramatsu Y, Suto A, Kashiwakuma D, Kanari H, Kagami S, Ikeda K, Hirose K, Watanabe N, Grusby MJ, Iwamoto I, Nakajima H
- Journal Title
  
  J. Leukoc. Biol
  
  Volume: 87 Pages: 703-712
- DOI
  10.1189/jlb.0909639
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255
[Journal Article] Role of Th2 cells in IgG4-related lacrimal gland enlargement.2010
- Author(s)
  Kanari H, Kagami S, Suto A, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Arch Allergy Immunol. 152
  
  Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immune responses2010
- Author(s)
  Kashiwakuma D, Suto A, Hiramatsu Y, Ikeda K, Takatori H, Suzuki K, Kagami S, Hirose K, Watanabe N, Iwamoto I, Nakajima H
- Journal Title
  
  J Immunol
  
  Volume: 185 Pages: 2730-2736
- DOI
  10.4049/jimmunol.0903839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255, KAKENHI-PROJECT-22790925
[Journal Article] Role of Th2 cells in IgG4-related lacrimal gland enlargement2010
- Author(s)
  Kanari H, Kagami S, Kashiwakuma D, Oya Y, Furuta S, Ikeda K, Suto A, Suzuki K, Hirose K, Watanabe N, Okamoto Y, Yamamoto S, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Arch. Allergy Immunol
  
  Volume: 152
- DOI
  10.1159/000312125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255
[Journal Article] c-Maf activates the promoter and enhancer of IL-21 gene while TGF-β inhibits c-Maf-induced IL-21 expression in CD4^+ T cells.2010
- Author(s)
  Hiramatsu Y, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J.Leukoc.Biol. 87
  
  Pages: 703-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Role of Th2 cells in IgG4-related lacrimal gland enlargement2010
- Author(s)
  Kanari H, Kagami S, Suto A, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Arch Allergy Immunol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] c-Maf activates the promoter and enhancer of IL-21 gene while TGF-b inhibits c-Maf-induced IL-21 expression in CD4^<+> T cells.2010
- Author(s)
  Hiramatsu Y, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J Leukoc Biol. 87
  
  Pages: 703-712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Role of Th2 cells in IgG4-related lacrimal gland enlargement.2010
- Author(s)
  Kanari H, Kagami S, Suto A, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 152 Pages: 47-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immne responses.2010
- Author(s)
  Kashiwakuma D, Suto A, Kagami S, Nakajima H, et al
- Journal Title
  
  J Immunol
  
  Volume: 1185 Pages: 2730-2736
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3^+ regulatory T cells2009
- Author(s)
  Kagami S, Suto A, Watanabe N, Nakajima H, et al
- Journal Title
  
  Int.Immunol. 21
  
  Pages: 679-89
- NAID
  40016949809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3^+ regulatory T cells2009
- Author(s)
  Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H, et.al.
- Journal Title
  
  Int. Immunol. (In press)
- NAID
  40016949809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060005
[Journal Article] Protein geranylgeranylation regulates the balance between Thl7 cells and Foxd3^+ reaulatory T cells2009
- Author(s)
  Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int. Immunol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] STAT6 Inhibits T-bet-independent Th1 cell differentiation.2009
- Author(s)
  Tamachi T, Takatori H, Kagami S, Nakajima H, et al
- Journal Title
  
  Biochem Biophys Res Commun. 382
  
  Pages: 751-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] STAT6 Inhibits T-bet-independent Th1 cell differentiation2009
- Author(s)
  Tamachi T, Takatori H, Fujiwara M, Hirose K, Maezawa Y, Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 382 Pages: 751-755
- DOI
  10.1016/j.bbrc.2009.03.101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255
[Journal Article] Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3^+ regulatory T cells2009
- Author(s)
  Kagami S, Owada T, Kanari H, Saito Y, Suto A, Ikeda K, Hirose K, Watanabe N, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Immunol
  
  Volume: 21 Pages: 679-689
- DOI
  10.1093/intimm/dxp037
- NAID
  40016949809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390255
[Journal Article] Protein geranylgeranylation regulates the balance between Th17 cells and Foxp3^<+> regulatory T cells.2009
- Author(s)
  Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Immunol. 21
  
  Pages: 679-689
- NAID
  40016949809
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Overlapping and Distinct Roles of STAT4 and T-bet in the Regulation of T Cell Differentiation and Allergic Airway Inflammation2008
- Author(s)
  Furuta S, Kagami S-I, Hirose K Watanabe N, Nakajima H (他5名)
- Journal Title
  
  J. Immunol 180
  
  Pages: 6656-6662
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] Development and characterization of IL-21-producing CD4^+ T cells2008
- Author(s)
  Suto A, Kagami S-I, Watanabe N, Nakajima H. et.al.
- Journal Title
  
  J. Exp. Med. 205
  
  Pages: 1369-1379
- NAID
  40016295272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060005
[Journal Article] Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation2008
- Author(s)
  Furuta S, Kagami S-I, Suto A, Watanabe N, Nakajima H, et al
- Journal Title
  
  J. Immunol 180
  
  Pages: 6656-6662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Development and characterization of IL-21-producing CD4^<+> T cells.2008
- Author(s)
  Suto A, Kashiwakuma D, Kagami S, Nakajima H, et al
- Journal Title
  
  J Exp Med. 205
  
  Pages: 1369-1379
- NAID
  40016295272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] IL-23 and Th17 cells enhance Th2 cell-mediated eosinophilic airway inflammation in mice.2008
- Author(s)
  Wakashin H, Hirose K, Kagami S, Nakajima H, et al
- Journal Title
  
  Am J Respir Crit Care Med. 178
  
  Pages: 1023-1032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Overlapping and Distinct Roles of Stat4 and T-bet in the Regulation of T Cell Differentiation and Allergic Airway Inflammation2008
- Author(s)
  Furuta S, Kagami S-I, Hirose K, Watanabe N, Nakajima H.
- Journal Title
  
  J. Immunol 180
  
  Pages: 6656-6662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cvtokine production from murine mast cells2008
- Author(s)
  Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Arch Allergy Immunol 146
  
  Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cytokine production from murine mast cells.2008
- Author(s)
  Kagami S, Suto A, Watanabe N, Iwamoto I, Nakajima H, et al
- Journal Title
  
  Int Arch Allergy Immunol. 146
  
  Pages: 61-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and alleraic airway inflammation2008
- Author(s)
  Furuta S, Kagami S-I, Suto A, Watanabe N, Nakajima H, et.al.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 6656-6662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060005
[Journal Article] Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation2008
- Author(s)
  Furuta S, Kagami S, Hirose K, Watanabe N, Nakajima H (他5名)
- Journal Title
  
  J. Immunol 180(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] Overlapping and distinct roles of STAT4 and T-bet in the regulation of T cell differentiation and allergic airway inflammation.2008
- Author(s)
  Furuta S, Kagami S, Suto A, Watanabe N, Nakajima H, et al
- Journal Title
  
  J Immunol. 180
  
  Pages: 6656-6662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591184
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recruitment into the airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Wakashin H, Watanabe N, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 119
  
  Pages: 662-670
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] BTLA inhibits antigen-induced eosinophil recuitment into the airways.2007
- Author(s)
  Tamachi T, Watanabe N, Oya Y, Kagami S-I, Hirose K, Saito Y, Iwamoto I, Nakajima H.
- Journal Title
  
  Int. Arch. Allergy Immunol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recruitment into the airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Watanabe N, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 119
  
  Pages: 662-670
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] BTLA inhibits antigen-induced eosinophil recruitment into the airways2007
- Author(s)
  Tamachi T, Watanabe N, Oya Y, Kagami S-I, Hirose K, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Arch. Allergy Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recruitment into the airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Wakashin H, Watanabe N, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology (in press)
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] T-bet Inhibits Both Th2 Cell-mediated Eosinophil Recruitment and Th17 Cell-mediated Neutrophil Recruitment into the Airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Saito Y, Iwamoto I, Nakajima H (他4名)
- Journal Title
  
  J. Allergy Clin. Immunol. 119
  
  Pages: 662-670
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] Expression of Tyk2 in Dendritic Cells is Required for IL-12, IL-23, and IFN-γ Production and the Induction of Th1 Cell Differentiation2007
- Author(s)
  Tokumasa N, Suto A, Kagami S-I, Watanabe N, Iwamoto I, Nakajima H.
- Journal Title
  
  Blood 110
  
  Pages: 553-560
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recuitment into the airways.2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H.
- Journal Title
  
  J. Allergy Clin. Immunol. 119
  
  Pages: 662-670
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] BTLA inhibits antigen-induced eosinophil recruitment into the airways2007
- Author(s)
  Tamachi T, Watanabe N, Oya Y, Kagami S-I, Hirose K, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Arch. Allergy Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] BTLA inhibits antigen-induced eosinophil recruitment into the airways2007
- Author(s)
  Tamachi T, Watanabe N, Oya Y, Kagami S-I, Hirose K, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Arch. Allergy Immunol. (in press)
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Thl7 cell-mediated neutrophil recnlitment into the airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S, Saito Y, Iwamoto I, Nakajima H (他4名)
- Journal Title
  
  J. Allergy Clin. Immunol. 119
  
  Pages: 662-670
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recruitment into the airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Wakashin H, Watanabe N, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology (in press)
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] T-bet inhibits both Th2 cell-mediated eosinophil recruitment and Th17 cell-mediated neutrophil recruitment into the airways2007
- Author(s)
  Tamachi T, Watanabe N, Oya Y, Kagami S-I, Hirose K, Saito Y, Iwamoto I, Nakajima H
- Journal Title
  
  Int. Arch. Allergy Immunol. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] Expression of Tyk2 in Dendritic Cells is Required for IL-12, IL-23, and IFN-g Production and the Induction of Th1 Cell Differentiation2007
- Author(s)
  Tokumasa N, Suto A, Kagami S-I, Watanabe N, Iwamoto I, Nakalima H (他4名)
- Journal Title
  
  Blood 110
  
  Pages: 553-560
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] Expression of Tyk2 in dendritic cells is required for IL-12, IL-23, and IFN-γ production and the induction of Thl cell differentiation2007
- Author(s)
  Tokumasa N, Suto A, Kagami S-i, Watanabe N, Iwamoto I, Nakaiima H (他4名)
- Journal Title
  
  Blood 110
  
  Pages: 553-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] T-bet Inhibits Both Th2 Cell-mediated Eosinophil Recruitment and Th17 Cell Mediated Neutrophil Recruitment into Airways2007
- Author(s)
  Fujiwara M, Hirose K, Kagami S-I, Saito Y, Iwamoto I, Nakajima H.
- Journal Title
  
  J. Allergy Clin. Immunol 119
  
  Pages: 662-670
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice2006
- Author(s)
  Tamachi T, Kagami S, Hatano M, Watanabe N, Saito Y, Tokuhisa T, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 118
  
  Pages: 606-614
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice2006
- Author(s)
  Tamachi T, Kagami S-I, Hatano M, Watanabe N, Saito Y, Tokuhisa T, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 118
  
  Pages: 606-614
- Data Source
  KAKENHI-PROJECT-18604002
[Journal Article] IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice2006
- Author(s)
  Tamachi T, Kagami S, Watanabe N, Saito Y, Tokuhisa T, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 118
  
  Pages: 606-614
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice2006
- Author(s)
  Tamachi T, Kagami S, Hatano M, Watanabe N, Saito Y, Tokuhisa T, Iwamoto I, Nakajima H
- Journal Title
  
  Journal of Allergy Clinical Immunology 118
  
  Pages: 606-614
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] IL-25 enhances allergic airway inflammation by amplifying a Th2 cell-dependent pathway in mice.2006
- Author(s)
  Tamachi T, Maezawa Y, Ikeda K, Kagami S, Hatano M, Seto Y, Suto A, Suzuki K, Watanabe N, Saito Y, Tokuhisa T, Iwamoto I, Nakajima H.
- Journal Title
  
  J. Allergy Clin. Immunol. 118
  
  Pages: 606-614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] Stat5a is essential for the proliferation and survival of murine mast cells2005
- Author(s)
  Ikeda K, Nakajima H, Suzuki K, Watanabe N, Kagami S-i, Iwamoto I
- Journal Title
  
  Int.Arch.Allergy Immunol. 137
  
  Pages: 45-50
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] Stat5a inhibits IL-12-induced Th1 cell differentiation through the induction of SOCS3 expression2005
- Author(s)
  Takatori H, Nakajima H, Kagami S-i, Hirose K, Suto A, Iwamoto I
- Journal Title
  
  Journal of Immunology 174
  
  Pages: 4105-4112
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] Stat5a inhibits IL-12-induced Th1 cell differentiation through the iniduction of SOCS3 expression2005
- Author(s)
  Takatori H, Nakajima H, Kagami S-i, Hirose K, Suto A, Iwamoto I
- Journal Title
  
  Journal of Immunology 174
  
  Pages: 4105-4112
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] Stat5a is essential for the proliferation and survival of murine mast cells2005
- Author(s)
  Ikeda K, Nakajima H, Suzuki K, Watanabe N, Kagami S-i, _Iwamoto_I.
- Journal Title
  
  Int.Arch.Allergy Immunol. 137
  
  Pages: 45-50
- Data Source
  KAKENHI-PROJECT-17591029
[Journal Article] Indispensable role of Stat5a in Stat6-independent Th2 cell differentiation and allergic airway inflammation.2005
- Author(s)
  Takatori H, Nakajima H, Hirose K, Kagami S-i, Iwamoto I
- Journal Title
  
  Journal of Immunology 174
  
  Pages: 3734-3740
- Data Source
  KAKENHI-PROJECT-17047008
[Journal Article] Indispensable role of Stat5a in Stat6-independent Th2 cell differentiation and allergic airway inflammation.2005
- Author(s)
  Takatori H, Nakajima H, Hirose K, Kagami S-i, Iwamoto I
- Journal Title
  
  Journal of Immunology 174
  
  Pages: 3734-3740
- Data Source
  KAKENHI-PROJECT-17591029
[Patent] 関節リウマチに対する抗IL-6受容体抗体療法の有効性の予測方法2011
- Inventor(s)
  中島裕史、池田啓、加々美新一郎、鈴木快枝、中山俊憲、岩本逸夫
- Industrial Property Rights Holder
  中島裕史、池田啓、加々美新一郎、鈴木快枝、中山俊憲、岩本逸夫
- Industrial Property Number
  2011-156921
- Filing Date
  2011
- Data Source
  KAKENHI-PROJECT-23591433
[Patent] 関節リウマチに対する抗IL-6受容体抗体療法の有効性の予測方法2011
- Inventor(s)
  中島裕史、池田啓、加々美新一郎、鈴木快枝、中山俊憲、岩本逸夫、古田俊介、小原收、野中謙、山下政克、的場亮
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Number
  2011-156921
- Filing Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-21390255
[Patent] 関節リウマチに対する抗IL-6受容体抗体療法の有効性の予測方法2011
- Inventor(s)
  中島裕史, 池田啓, 加々美新一郎, 鈴木快枝, 中山俊憲, 岩本逸夫, 古田俊介, 小原收, 野中謙, 山下政克, 的場亮
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Number
  2011-156921
- Filing Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-21390255
[Patent] ゲラニルゲラニル化阻害による制御性T細胞の分化誘導およびその治療応用2009
- Inventor(s)
  中島裕史、加々美新一郎、須藤明、金成博子
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Number
  2009-029880
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-20060005
[Patent] ゲラニルゲラニル化阻害による制御性T細胞の分化誘導およびその治療応用2009
- Inventor(s)
  中島裕史、加々美新一郎、須藤明、金成博子
- Industrial Property Rights Holder
  千葉大学
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-20591184
[Patent] ゲラニルゲラニル化阻害による制御性T細胞の分化誘導およびその治療応用2009
- Inventor(s)
  中島裕史、加々美新一郎、須藤明、金成博子
- Industrial Property Rights Holder
  千葉大学
- Industrial Property Number
  2009-029880
- Filing Date
  2009-02-12
- Data Source
  KAKENHI-PROJECT-20591184
[Presentation] IgG4関連涙腺腫脹症例におけるPGD2-CRTH2経路の役割2011
- Author(s)
  加々美新一郎、細川淳一、山形美絵子、高取宏昌、廣瀬晃一、中島裕史
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591433
[Presentation] IgG4関連涙腺腫脹症例におけるPGD2-CRTH2経路の役割2011
- Author(s)
  加々美新一郎、齊藤ゆかり、川島沙紀、廣瀬晃一、中島裕史
- Organizer
  アレルギー好酸球研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591433
[Presentation] 自己免疫性血小板減少性紫斑病に対してリツキシマブが有効であったIgG4関連疾患の1例2011
- Author(s)
  加々美新一郎、岩田有史、高取宏昌、中島裕史
- Organizer
  第23回日本アレルギー学会春季臨床大会
- Place of Presentation
  千葉市
- Data Source
  KAKENHI-PROJECT-23591433
[Presentation] 高IgE血症、好酸球増多を伴ったIgG4関連疾患におけるT細胞分化の検討2009
- Author(s)
  加々美新一郎、廣瀬晃一、須藤明、渡邊紀彦、中島裕史
- Organizer
  日本アレルギー学会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20591184
[Presentation] 高IgE血症、好酸球増多を伴ったIgG4関連疾患におけるT細胞分化の検討2009
- Author(s)
  加々美新一郎、廣瀬晃一、須藤明、渡邊紀彦、中島裕史
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20591184
[Presentation] Th17細胞及びFoxP3陽性細胞分化に対するHMG-CoA還元酵素阻害剤の作用2008
- Author(s)
  加々美新一郎、廣瀬晃一、須藤明、渡邊紀彦、中島裕史
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591184
[Presentation] Th17細胞及びFoxP3 陽性細胞分化に対するHMG-CoA還元酵素阻害剤の作用2008
- Author(s)
  加々美新一郎、廣瀬晃一、須藤明、渡邊紀彦、中島裕史
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-01
- Data Source
  KAKENHI-PROJECT-20591184
[Presentation] Role of Stat4 and T-bet in the Allergic Airway Inflammation2007
- Author(s)
  Furuta S, Kagami S-I, Suto A, Hirose K, Watanabe N, Iwamoto I, Nakajima H, Saito Y.
- Organizer
  Annual Meeting of Japanese Society for Immunology
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18604002
[Presentation] アレルギー性気道炎症におけるStat4とT-betの役割の解明2007
- Author(s)
  古田俊介, 加々美新一郎, 他5人
- Organizer
  第37回目本免疫学会総会・学術集会
- Place of Presentation
  東京、グランドプリンスホテル新高輪
- Year and Date
  2007-11-20
- Data Source
  KAKENHI-PROJECT-18604002
[Presentation] アレルギー性気道炎症におけるStat4とT-betの役割の解明2007
- Author(s)
  古田俊介, 加々美新一郎、他5名
- Organizer
  第37回日本免疫学会・学術集会
- Place of Presentation
  東京、グランドプリンスホテル新高輪
- Year and Date
  2007-11-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18604002

1. NAKAJIMA Hiroshi (00322024)

# of Collaborated Projects: 6 results

# of Collaborated Products: 64 results
2. WATANABE Norihiko (20375653)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
3. SUTO Akira (50447306)

# of Collaborated Projects: 3 results

# of Collaborated Products: 31 results
4. HIROSE Koichi (90400887)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
5. 池田啓 (10456014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. TAKATORI Hiroaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAGAMI Shin-ichiro 加々美 新一郎

Research Projects

Research Products

Co-Researchers

関節リウマチのTh17細胞分化におけるWnt/カテニン-SGK1経路の役割の解明Principal Investigator

Principal Investigator

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Analysis of helper T cell subset in severe asthma for the development of new immunotherapy

Principal Investigator

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新規ヘルパーT細胞分画IL-21産生T細胞の自己免疫疾患における役割の解明

Principal Investigator

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Research Category

Review Section

Research Institution

Analysis of regulation of antigen-specific IgE production in BALTPrincipal Investigator

Principal Investigator

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Research Field

Research Institution

Comprehensive Analysis of Stat5a Target Genes in Th2 Cell DifferentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アレルギー性気道炎症の対する免疫監視機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms underlying IL-4-induced IFN-γ production in plasmacytoid dendritic cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床・アレルギー科(ゲラニルゲラニル化阻害によるTh17細胞/Treg細胞バランスの制御)2009

Author(s)

Publisher

Data Source

[Journal Article] Roles of CRTH2+ CD4+ T Cells in Immunoglobulin G4-Related Lacrimal Gland Enlargement2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lack of B and T lymphocyte attenuator exacerbates autoimmune disorders and induces Fas- independent liver injury in MRL- lpr/lpr mice2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.2010

Author(s)

Journal Title

Data Source

[Journal Article] Protective roles of B and T lymphocyte attenuator in NKT cell-mediated experimental hepatitis.2010

Author(s)

Journal Title

Data Source

[Journal Article] B and T lymphocyte attenuator suppresses IL-21 production from follicular Th cells and subsequent humoral immne responses.2010

Author(s)

Journal Title

Data Source

[Journal Article] Protective roles of B and T lymphocyte attenuator (BTLA) in NKT cell-mediated experimental hepatitis2010

Author(s)

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DOI

Data Source

[Journal Article] c-Maf activates the promoter and enhancer of IL-21 gene while TGF-β inhibits c-Maf-induced IL-21expression in CD4^+ T cells2010

Author(s)

Journal Title

KAGAMI Shin-ichiro 加々美新一郎