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Tsutsumi Makiko  堤 真紀子

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TSUTSUMI Makiko  堤 真紀子

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Researcher Number 30377907
Other IDs
Affiliation (Current) 2025: 藤田医科大学, 医科学研究センター, 助教
Affiliation (based on the past Project Information) *help 2024: 藤田医科大学, 医科学研究センター, 助教
2018: 藤田医科大学, 総合医科学研究所, 助教
2013 – 2017: 藤田保健衛生大学, 総合医科学研究所, 助教
2010 – 2011: 藤田保健衛生大学, 総合医科学研究所, 助教
Review Section/Research Field
Principal Investigator
Human genetics / Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
減数分裂 / 習慣流産 / 卵母細胞 / コヒーシン / 不妊症 / 高齢出産 / 染色体異数性 / 高齢妊娠 / 染色体転座 / 精子形成 … More / 不妊 / 均衡型染色体相互転座 / 染色体の分離異常 / コヒーシンの減少 / 染色体不分離 Less
  • Research Projects

    (4 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (1 People)
  •  高齢妊娠に伴う染色体異常の予防に向けてそのメカニズムを新規モデル系により解明するPrincipal Investigator

    • Principal Investigator
      堤 真紀子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Fujita Health University
  •  Meiotic regulation and its epigenetic analyses of male-female differences using model mice carrying a balanced reciprocal translocationPrincipal Investigator

    • Principal Investigator
      Tsutsumi Makiko
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human genetics
    • Research Institution
      Fujita Health University
  •  Mechanism of the age-related increase of the chromosomal segregation errors during oogenesis in humansPrincipal Investigator

    • Principal Investigator
      TSUTSUMI Makiko
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human genetics
    • Research Institution
      Fujita Health University
  •  Analysis of the distribution of cohesin in human oocytes to figure out the mechanism of age-related increase of chromosomal nondisjunction.Principal Investigator

    • Principal Investigator
      TSUTSUMI Makiko
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human genetics
    • Research Institution
      Fujita Health University

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

  • [Journal Article] Age-related decrease of meiotic cohesins in human oocyte2014

    • Author(s)
      Tsutsumi M, Fujiwara R, Nishizawa H, Ito M, Kogo H, Inagaki H, Ohye T, Kato T, Fujii T, Kurahashi H
    • Journal Title

      PLoS One

      Volume: 9, Issue: 5 Pages: 1-8

    • DOI

      10.1371/journal.pone.0096710

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-24590263, KAKENHI-PROJECT-25860255, KAKENHI-PROJECT-25860256, KAKENHI-PROJECT-26462540, KAKENHI-PROJECT-26670171
  • [Journal Article] Screening of genes involved in chromosome segregation during meiosis I : in vitro gene transfer to mouse fetal oocytes.2012

    • Author(s)
      Makiko Tsutsumi, Hiroe Kowa-Sugiyama, Hasbaira Bolor, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Kouji Yamada, Mariko Taniguchi-Ikeda, Tatsushi Toda and Hiroki Kurahashi
    • Journal Title

      Journal of Human Genetics

    • NAID

      10031056588

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] 均衡型相互転座モデルマウスの精子形成における性染色体不活化異常の発生機構2017

    • Author(s)
      堤真紀子、 加藤武馬、稲垣秀人、倉橋浩樹
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-15K08334
  • [Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016

    • Author(s)
      Makiko Tsutsumi, Takema Kato, Hidehito Inagaki, Tamae Ohye, Hiroki Kurahashi
    • Organizer
      ICHG2016
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08334
  • [Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016

    • Author(s)
      Makiko Tsutsumi, Takema Kato, Hidehito Inagaki, Tamae Ohye, Hiroki Kurahashi
    • Organizer
      ICHG 2016
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08334
  • [Presentation] 均衡型相互転座保因者モデルマウスにおける減数分裂期の性染色体不活化異常の発生機構の解明2015

    • Author(s)
      堤真紀子, 加藤武馬, 稲垣秀人, 大江瑞恵, 倉橋浩樹
    • Organizer
      日本人類遺伝学会第60回大会
    • Place of Presentation
      京王プラザホテル(新宿)
    • Year and Date
      2015-10-14
    • Data Source
      KAKENHI-PROJECT-15K08334
  • [Presentation] Decrease of meiotic cohesins with maternal age in human oocytes2014

    • Author(s)
      Makiko Tsutsumi, Reiko Fujiwara, Haruki Nishizawa, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Takema Kato, Hiroki Kurahashi
    • Organizer
      The EUROPEAN HUMAN GENETICS CONFERENCE 2014
    • Place of Presentation
      ミラノ(イタリア)
    • Data Source
      KAKENHI-PROJECT-25860255
  • [Presentation] Mechanism of age-related increase of chromosome segregation error in human oocytes2013

    • Author(s)
      堤真紀子, 藤原怜子, 池田怜美, 西澤春紀, 向後 寛, 稲垣秀人, 大江瑞恵, 加藤武馬, 倉橋浩樹
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸市(兵庫県)
    • Data Source
      KAKENHI-PROJECT-25860255
  • [Presentation] Age-related decrease of meiotic cohesins in human oocytes2013

    • Author(s)
      Makiko Tsutsumi, Reiko Fujiwara, Haruki Nishizawa, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Takema Kato, Hiroki Kurahashi
    • Organizer
      アメリカ人類遺伝学会第63回大会
    • Place of Presentation
      ボストン(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-25860255
  • [Presentation] ヒト卵母細胞における加齢依存性染色体分離異常の発生機構2013

    • Author(s)
      堤真紀子, 藤原怜子, 池田怜美, 西澤春紀, 向後 寛, 稲垣秀人, 大江瑞恵, 加藤武馬, 倉橋浩樹
    • Organizer
      日本人類遺伝学会第58回大会
    • Place of Presentation
      仙台市(宮城県)
    • Data Source
      KAKENHI-PROJECT-25860255
  • [Presentation] SYCP3変異による習慣流産の発症メカニズムの解析2011

    • Author(s)
      堤真紀子
    • Organizer
      第43回藤田学園医学会
    • Place of Presentation
      藤田保健衛生大学(愛知)
    • Year and Date
      2011-10-06
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] Mutation in the SYCP3 gene identified in a woman with recurrent pregnancy loss affect the synaptonemal complex conformation at meiotic prophase I2011

    • Author(s)
      Makiko Tsutsumi
    • Organizer
      第12回国際人類遺伝学会
    • Place of Presentation
      モントリオール・コンベンションセンター(カナダ)
    • Year and Date
      2011-10-12
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] Mutation in the SYCP3 gene identified in women with recurrent pregnancy loss affects pairing of the homologous chromosomes during the prophase of meiosis I2011

    • Author(s)
      堤真紀子
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] Mutation in the SYCP3 gene identified in a woman with recurrent pregnancy loss affects pairing of the homologous chromosomes during the prophase of meiosis2011

    • Author(s)
      堤真紀子
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川)
    • Year and Date
      2011-12-13
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] 卵母細胞の体外培養系を用いた習慣流産原因遺伝子の解析2010

    • Author(s)
      堤真紀子
    • Organizer
      BMB2010
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] 卵母細胞の体外培養系を用いた習慣流産原因遺伝子の解析2010

    • Author(s)
      堤真紀子
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2010-12-09
    • Data Source
      KAKENHI-PROJECT-22790334
  • [Presentation] Decrease of meiotic cohesins with maternal age in human oocytes

    • Author(s)
      Tsutsumi, R. Fujiwara, H. Nishizawa, H. Kogo, H. Inagaki, T. Ohye, T. Kato, T. Fujii, H. Kurahashi
    • Organizer
      2014年ヨーロッパ人類遺伝学会
    • Place of Presentation
      ミラノ・コングレッション(イタリア)
    • Year and Date
      2014-05-31 – 2014-06-03
    • Data Source
      KAKENHI-PROJECT-25860255
  • 1.  倉橋 浩樹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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