TSUTSUMI Makiko 堤真紀子

Researcher Number	30377907
Other IDs
Affiliation (Current)	2022: 藤田医科大学, 医科学研究センター, 助教
Affiliation (based on the past Project Information) *help	2018: 藤田医科大学, 総合医科学研究所, 助教 2013 – 2017: 藤田保健衛生大学, 総合医科学研究所, 助教 2010 – 2011: 藤田保健衛生大学, 総合医科学研究所, 助教
Review Section/Research Field	Principal Investigator Human genetics
Keywords	Principal Investigator 減数分裂 / 習慣流産 / 卵母細胞 / 高齢出産 / 不妊症 / コヒーシン / 染色体不分離 / コヒーシンの減少 / 染色体の分離異常 / 均衡型染色体相互転座 / 不妊 / 精子形成 / 染色体転座

Meiotic regulation and its epigenetic analyses of male-female differences using model mice carrying a balanced reciprocal translocationPrincipal Investigator
- Principal Investigator
  
  Tsutsumi Makiko
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human genetics
- Research Institution
  Fujita Health University
Mechanism of the age-related increase of the chromosomal segregation errors during oogenesis in humansPrincipal Investigator
- Principal Investigator
  
  TSUTSUMI Makiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  Fujita Health University
Analysis of the distribution of cohesin in human oocytes to figure out the mechanism of age-related increase of chromosomal nondisjunction.Principal Investigator
- Principal Investigator
  
  TSUTSUMI Makiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  Fujita Health University

All 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Age-related decrease of meiotic cohesins in human oocytes.2014
- Author(s)
  Tsutsumi M, Fujiwara R, Nishizawa H, Ito M, Kogo H, Inagaki H, Ohye T, Kato T, Fujii T, Kurahashi H
- Journal Title
  
  PLos One
  
  Volume: 9, Pages: 1-8
- DOI
  10.1371/journal.pone.0096710
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390085, KAKENHI-PROJECT-24590263, KAKENHI-PROJECT-25860255, KAKENHI-PROJECT-25860256, KAKENHI-PROJECT-26462540, KAKENHI-PROJECT-26670171
[Journal Article] Screening of genes involved in chromosome segregation during meiosis I : in vitro gene transfer to mouse fetal oocytes.2012
- Author(s)
  Makiko Tsutsumi, Hiroe Kowa-Sugiyama, Hasbaira Bolor, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Kouji Yamada, Mariko Taniguchi-Ikeda, Tatsushi Toda and Hiroki Kurahashi
- Journal Title
  
  Journal of Human Genetics
- NAID
  10031056588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] 均衡型相互転座モデルマウスの精子形成における性染色体不活化異常の発生機構2017
- Author(s)
  堤真紀子、加藤武馬、稲垣秀人、倉橋浩樹
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-15K08334
[Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016
- Author(s)
  Makiko Tsutsumi, Takema Kato, Hidehito Inagaki, Tamae Ohye,　Hiroki Kurahashi
- Organizer
  ICHG2016
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08334
[Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016
- Author(s)
  Makiko Tsutsumi, Takema Kato, Hidehito Inagaki, Tamae Ohye, Hiroki Kurahashi
- Organizer
  ICHG 2016
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08334
[Presentation] 均衡型相互転座保因者モデルマウスにおける減数分裂期の性染色体不活化異常の発生機構の解明2015
- Author(s)
  堤真紀子, 加藤武馬, 稲垣秀人, 大江瑞恵, 倉橋浩樹
- Organizer
  日本人類遺伝学会第６０回大会
- Place of Presentation
  京王プラザホテル（新宿）
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-15K08334
[Presentation] Decrease of meiotic cohesins with maternal age in human oocytes2014
- Author(s)
  Makiko Tsutsumi, Reiko Fujiwara, Haruki Nishizawa, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Takema Kato, Hiroki Kurahashi
- Organizer
  The EUROPEAN HUMAN GENETICS CONFERENCE 2014
- Place of Presentation
  ミラノ（イタリア）
- Data Source
  KAKENHI-PROJECT-25860255
[Presentation] Mechanism of age-related increase of chromosome segregation error in human oocytes2013
- Author(s)
  堤真紀子, 藤原怜子, 池田怜美, 西澤春紀, 向後　寛, 稲垣秀人, 大江瑞恵, 加藤武馬, 倉橋浩樹
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸市（兵庫県）
- Data Source
  KAKENHI-PROJECT-25860255
[Presentation] Age-related decrease of meiotic cohesins in human oocytes2013
- Author(s)
  Makiko Tsutsumi, Reiko Fujiwara, Haruki Nishizawa, Hiroshi Kogo, Hidehito Inagaki, Tamae Ohye, Takema Kato, Hiroki Kurahashi
- Organizer
  アメリカ人類遺伝学会第６３回大会
- Place of Presentation
  ボストン（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-25860255
[Presentation] ヒト卵母細胞における加齢依存性染色体分離異常の発生機構2013
- Author(s)
  堤真紀子, 藤原怜子, 池田怜美, 西澤春紀, 向後　寛, 稲垣秀人, 大江瑞恵, 加藤武馬, 倉橋浩樹
- Organizer
  日本人類遺伝学会第５８回大会
- Place of Presentation
  仙台市（宮城県）
- Data Source
  KAKENHI-PROJECT-25860255
[Presentation] SYCP3変異による習慣流産の発症メカニズムの解析2011
- Author(s)
  堤真紀子
- Organizer
  第43回藤田学園医学会
- Place of Presentation
  藤田保健衛生大学(愛知)
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] Mutation in the SYCP3 gene identified in a woman with recurrent pregnancy loss affect the synaptonemal complex conformation at meiotic prophase I2011
- Author(s)
  Makiko Tsutsumi
- Organizer
  第12回国際人類遺伝学会
- Place of Presentation
  モントリオール・コンベンションセンター(カナダ)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] Mutation in the SYCP3 gene identified in women with recurrent pregnancy loss affects pairing of the homologous chromosomes during the prophase of meiosis I2011
- Author(s)
  堤真紀子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] Mutation in the SYCP3 gene identified in a woman with recurrent pregnancy loss affects pairing of the homologous chromosomes during the prophase of meiosis2011
- Author(s)
  堤真紀子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] 卵母細胞の体外培養系を用いた習慣流産原因遺伝子の解析2010
- Author(s)
  堤真紀子
- Organizer
  BMB2010
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] 卵母細胞の体外培養系を用いた習慣流産原因遺伝子の解析2010
- Author(s)
  堤真紀子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22790334
[Presentation] Decrease of meiotic cohesins with maternal age in human oocytes
- Author(s)
  Tsutsumi, R. Fujiwara, H. Nishizawa, H. Kogo, H. Inagaki, T. Ohye, T. Kato, T. Fujii, H. Kurahashi
- Organizer
  2014年ヨーロッパ人類遺伝学会
- Place of Presentation
  ミラノ・コングレッション（イタリア）
- Year and Date
  2014-05-31 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-25860255

1. 倉橋浩樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 向後寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 加藤武馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 藤井多久磨

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TSUTSUMI Makiko 堤 真紀子

Research Projects

Research Products

Co-Researchers

Meiotic regulation and its epigenetic analyses of male-female differences using model mice carrying a balanced reciprocal translocationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of the age-related increase of the chromosomal segregation errors during oogenesis in humansPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the distribution of cohesin in human oocytes to figure out the mechanism of age-related increase of chromosomal nondisjunction.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Age-related decrease of meiotic cohesins in human oocytes.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Screening of genes involved in chromosome segregation during meiosis I : in vitro gene transfer to mouse fetal oocytes.2012

Author(s)

Journal Title

NAID

Data Source

[Presentation] 均衡型相互転座モデルマウスの精子形成における性染色体不活化異常の発生機構2017

Author(s)

Organizer

Data Source

[Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Spermatogenic failure by impaired meiotic sex chromosome inactivation in a mouse with reciprocal translocation2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 均衡型相互転座保因者モデルマウスにおける減数分裂期の性染色体不活化異常の発生機構の解明2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Decrease of meiotic cohesins with maternal age in human oocytes2014

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Mechanism of age-related increase of chromosome segregation error in human oocytes2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Age-related decrease of meiotic cohesins in human oocytes2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒト卵母細胞における加齢依存性染色体分離異常の発生機構2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] SYCP3変異による習慣流産の発症メカニズムの解析2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

TSUTSUMI Makiko 堤真紀子