Koga Yuichi 古賀雄一

… Alternative Names

KOGA Yuichi 古賀雄一

KOGA Yuuichi 古賀雄一

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Researcher Number	30379119
Other IDs
Affiliation (Current)	2023: 岡山理科大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 大阪大学, 工学研究科, 准教授 2016 – 2017: 大阪大学, 工学研究科, 准教授 2015: 大阪大学, 工学(系)研究科(研究院), 准教授 2014: 大阪大学, 大学院工学研究科, 准教授 2013: 大阪大学, 工学(系)研究科(研究院), 准教授 … More 2011: 大阪大学, 大学院・工学研究科, 准教授 2010: 大阪大学, 工学研究科, 助教 2007 – 2008: Osaka University, 大学院・工学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Applied biochemistry / Applied microbiology / Basic Section 38030:Applied biochemistry-related Except Principal Investigator Applied biochemistry
Keywords	Principal Investigator 超好熱菌 / 古細菌 / 始原菌 / グリセロール代謝 / タンパク質工学 / リパーゼ / 光学選択性 / 結晶構造解析 / 機能改変 / たんぱく質工学 … More / 結晶構造解 / アーキア / 古細菌(始原菌) / Glycerol代謝経路 / プロテアーゼ / 蛋白質工学 / PrP / Subtilisin / 耐熱性酵素 / プリオン / プリオンタンパク質 / 可溶性改変 / binding scaffold / 熱安定性 / Binding scaffold / 人工抗体 / ファージディスプレイ / 可溶性発現 / Binfing scaffold / scaffold protein / thermalstability / phage display / antibody … More Except Principal Investigator サチライシン / セリンプロテアーゼ / 超好熱菌 / 成熟化 / プリオン / X線結晶構造解析 / タンパク質工学 / 微生物酵素 / 構造生物学 / プロペプチド / タンパク工学 / ジェリーロール / セルピン / クチナーゼ / ポリエステル / カルシウム結合部位 / メタゲノム / Ｘ線結晶構造解析 / セルラーゼ / 飽和変異 / プリオン分解 / 速度論的安定性 / ジスルフィド結合 / 菌体外漏出 Less

Development of binding scaffold with a protein from a hyperthermophilic archaeonPrincipal Investigator
- Principal Investigator
  
  Koga Yuichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Osaka University
Analysis of abnormal prion protein core structure by proteolysis at high temperaturePrincipal Investigator
- Principal Investigator
  
  Koga Yuichi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka University
Comprehensive analysis of glycerol metabolism in archaeaPrincipal Investigator
- Principal Investigator
  
  KOGA Yuichi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied microbiology
- Research Institution
  Osaka University
Development of a technology to degrade, remove or process persistent proteins with enzymes
- Principal Investigator
  
  KANAYA SHIGENORI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka University
Studies on glycerol metabolism of hyperthermophilic arhaeaPrincipal Investigator
- Principal Investigator
  
  KOGA Yuichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka University
Elucidation of the maturation mechanism of subtilisins from hyperthermophiles and development of their potential use
- Principal Investigator
  
  KANAYA Shigenori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka University
Thermodynamic analysis of chiral molecule recognition of enzymesPrincipal Investigator
- Principal Investigator
  
  KOGA Yuuichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Osaka University

[Book] Biotechnology of Microbial Enzymes, production, biocatalysis and industrial applications2016
- Author(s)
  Uehara, R., Takano, K., Kanaya, S. and Koga, Y.
- Total Pages
  608
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-15K07392
[Journal Article] Insertion loop‐mediated folding propagation governs efficient maturation of hyperthermophilic Tk‐subtilisin at high temperatures2021
- Author(s)
  Uehara R., Dan N., Amesaka H., Yoshizawa T., Koga Y.., Kanaya S., Takano K., Matsumura H., Tanaka SI.
- Journal Title
  
  FEBS Letters
  
  Volume: 594 Pages: 452-461
- DOI
  10.1002/1873-3468.14028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05827, KAKENHI-PROJECT-20K15721, KAKENHI-PUBLICLY-19H04735, KAKENHI-PUBLICLY-19H05401, KAKENHI-PUBLICLY-20H05516, KAKENHI-PROJECT-18K05445, KAKENHI-PROJECT-18K06094, KAKENHI-PROJECT-19K23733
[Journal Article] Production of monoclonal shark-derived immunoglobulin new antigen receptor antibodies using Chinese hamster ovary cell expression system2021
- Author(s)
  Hajime Enatsu, Nako Okamoto, Yoshiki Nomura, Masayoshi Onitsuka, Noriko Yamano-Adachi, Yuichi Koga, Takeshi Omasa
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 132 Issue: 3 Pages: 302-309
- DOI
  10.1016/j.jbiosc.2021.04.015
- NAID
  40022688030
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05827
[Journal Article] Affinity shift of ATP upon glycerol binding to a glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakarensis KOD12020
- Author(s)
  Hokao R., Matsumura H., Katsumi R., Angkawidjaja C., Takano K., Kanaya S., Koga Y.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 129 Issue: 6 Pages: 657-663
- DOI
  10.1016/j.jbiosc.2019.12.008
- NAID
  40022261697
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05827, KAKENHI-PUBLICLY-19H04735
[Journal Article] Anaerobic glycerol-3-phosphate dehydrogenase complex from hyperthermophilic archaeon Thermococcus kodakarensis KOD12019
- Author(s)
  Koga Y., Konishi K., Kobayashi A., Kanaya S., Takano K.
- Journal Title
  
  Journal of Bioscience and Bioengineering
  
  Volume: 127 Issue: 6 Pages: 679-685
- DOI
  10.1016/j.jbiosc.2018.11.012
- NAID
  40021920321
- ISSN
  1389-1723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05827
[Journal Article] Effects of Surfactant and a Hyperthermostable Protease on Infectivity of Scrapie-Infected Mouse Brain Homogenate.2015
- Author(s)
  Hirata, A., Sakudo, A., Takano, K., Kanaya, S. and Koga, Y.
- Journal Title
  
  J Biotechnol Biomater
  
  Volume: 5 Pages: 194-194
- DOI
  10.4172/2155-952x.1000194
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07392, KAKENHI-PROJECT-25450447
[Journal Article] Structural basis for salt-dependent folding of ribonuclease H1 from halophilic archaeon Halobacterium sp. NRC-1.2014
- Author(s)
  You, D.-J., Jongruja, N., Tannous, E., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 187 Pages: 119-128
- DOI
  10.1016/j.jsb.2014.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Proteolysis of abnormal prion protein with a thermostable protease from Thermococcus kodakarensis KOD12014
- Author(s)
  Koga, Y., Sakudo, A., Aranishi, M., Tanaka, S., Hirata, A., Takano, K., Ikuta, K., and Kanaya, S.
- Journal Title
  
  Appl Microbiol Biotechnol
  
  Volume: 98 Pages: 2113-2120
- DOI
  10.1007/s00253-013-5091-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055, KAKENHI-PROJECT-25450447
[Journal Article] Calcium-independent opening of lid1 of a family I.3 lipase by a single Asp to Arg mutation at the calcium-binding site.2014
- Author(s)
  Cheng, M., Angkawidjaja, C., Koga, Y., and Kanaya, S
- Journal Title
  
  Protein Eng. Des. Sel.
  
  Volume: 27 Pages: 169-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Crystal structure and thermodynamic and kinetic stability of metagenome-derived LC-cutinase.2014
- Author(s)
  Sulaiman, S., You, D.-J., Kanaya, E., Koga, Y., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 53 Pages: 1858-1869
- DOI
  10.1021/bi401561p
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Structural and mechanistic insights into the kynurenine aminotransferase-mediated excretion of kynurenic acid.2014
- Author(s)
  Okada, K., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 185 Pages: 257-266
- DOI
  10.1016/j.jsb.2014.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Structure and stability of metagenome-derived glycoside hydrolase family 12 cellulase, LC-CelA, a homolog of Cel12A from Rhodothermus marinus.2014
- Author(s)
  Okano, H., Ozaki, M., Kanaya, E., Kim, J.-J., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 4 Pages: 936-946
- DOI
  10.1016/j.fob.2014.10.013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Crystal structure of metagenome-derived LC9-RNase H1 with atypical DEDN active site motif.2013
- Author(s)
  Nguyen, T.-N., You, D.-J., Kanaya, E., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS Lett.
  
  Volume: 587 Pages: 1418-1423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Formation of the high-affinity calcium binding site in Pro-subtilisin E with the insertion sequence IS1 of Pro-Tk-subtilisin.2013
- Author(s)
  Uehara, R., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Pages: 9080-9088
- DOI
  10.1021/bi401342k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Enzymatic activity of a subtilisin homo log, Tk-SP, from Thermococcus kodakarensis in detergents and its ability to degrade the abnormal prion protein.2013
- Author(s)
  Hirata, A., Hori, Y., Koga, Y., Sakudo, A., Ikuta, K., Kanaya, S.,
- Journal Title
  
  BMC Biotechnology
  
  Volume: 13 Pages: 19-19
- DOI
  10.1186/1472-6750-13-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Evolvability of Thermophilic Proteins from Archaea and Bacteria2013
- Author(s)
  Takano, K., Aoi, A., Koga, Y., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Pages: 4774-4780
- DOI
  10.1021/bi400652c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055, KAKENHI-PROJECT-25440194
[Journal Article] Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid.2013
- Author(s)
  Nguyen, T.-N., You, D.-J., Matsumoto, H., Kanaya, E., Koga, Y., and Kanaya, S.
- Journal Title
  
  J. Struct. Biol.
  
  Volume: 182 Pages: 144-154
- DOI
  10.1016/j.jsb.2013.02.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Increase in activation rate of Pro-Tk-subtilisin by a single nonpolar-to-polar amino acid substitution at the hydrophobic core of the propeptide domain.2013
- Author(s)
  Yuzaki, K., Sanda, Y., You, D.-J., Uehara, R., Koga, Y., and Kanaya, S.
- Journal Title
  
  Protein Sci.
  
  Volume: 22 Pages: 1711-1721
- DOI
  10.1002/pro.2371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Investigating the structural dependence of protein stabilization by amino acid substitution.2013
- Author(s)
  Tadokoro, T., Kazama, H., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 52 Pages: 2839-2847
- DOI
  10.1021/bi400076f
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Role of N-terminal extension of Bacillus stearothermophilus RNase H2 and C-terminal extension of Thermotoga maritima RNase H2.2013
- Author(s)
  Permanasari, E.-D., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS J.
  
  Volume: 280 Pages: 5065-5079
- DOI
  10.1111/febs.12479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Accelerated maturation of Tk-subtilisin by a Leu→Pro mutation at the C-terminus of propeptide which reduces the binding of propeptide to Tk-subtilisin.2013
- Author(s)
  Uehara, R., Ueda, Y., You, D-J., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS Journal
  
  Volume: 280 Pages: 994-1006
- DOI
  10.1111/febs.12091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] A dual role of divalent metal ions in catalysis and folding of RNase H1 from extreme halophilic archaeon Halobacterium sp. NRC-1.2012
- Author(s)
  Tannous, E., Yokoyama, K., You, D-J., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS Open Bio
  
  Volume: 2 Pages: 345-352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Requirement of Ca2+ ions for the hyperthermostability of Tk-subtilisin from Thermococcus kodakarensis.2012
- Author(s)
  Uehara, R., Takeuchi, Y., Tanaka, S., Takano, K., Koga. Y., and Kanaya S.
- Journal Title
  
  Biochemistry
  
  Volume: 51 Pages: 5369-5378
- DOI
  10.1021/bi300427u
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Structure and characterization of RNase H3 from Aquifex aeolicus.2012
- Author(s)
  Jongruja, N., You, D-J., Angkawidjaja, C., Kanaya. E., Koga,
- Journal Title
  
  FEBS Journal
  
  Volume: 279 Pages: 2737-2753
- DOI
  10.1111/j.1742-4658.2012.08657.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Slow unfolding pathway of the hyper thermophilic Tk-RNase H2 examined by pulse proteolysis using the stable protease Tk-subtilisin.2012
- Author(s)
  Okada, J., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 51 Pages: 9178-9191
- DOI
  10.1021/bi300973n
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Requirement of lid2 for interfacial activation of a family I.3 lipase with unique two lid structures.2012
- Author(s)
  Cheng, M., Angkawidjaja, C., Koga, Y., and Kanaya, S.
- Journal Title
  
  FEBS Journal
  
  Volume: 279 Pages: 3727-3737
- DOI
  10.1111/j.1742-4658.2012.08734.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Requirement of insertion sequence IS1 for thermal adaptation of Pro-Tk-subtilisin from hyper thermophilic archaeon.2012
- Author(s)
  Uehara, R., Tanaka, S., Takano, K., Koga, Y., and Kanaya, S.
- Journal Title
  
  Extremophiles
  
  Volume: 16 Pages: 841-851
- DOI
  10.1007/s00792-012-0479-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24380055
[Journal Article] Inhibition of chymotrypsin-and subtilisin-like serine proteases with Tk-serpin from hyperthermophilic archaeon Thermococcus kodakaraensis.2011
- Author(s)
  Tanaka, S., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  Biochim.Biophys.Acta
  
  Volume: 1814 Pages: 299-307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] An alternative mature form of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis identified in the presence of Ca2+2011
- Author(s)
  Sinsereekul, N., Foophow, T., Yamanouchi, M., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  FEBS J.
  
  Volume: 278 Pages: 1901-1911
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] An alternative mature form of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis identified in the presence of Ca^<2+>2011
- Author(s)
  Sinsereekul, N., Foophow, T., Yamanouchi, M., Koga, Y., Takano, K. and Kanaya, S.
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 1901-1911
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/2144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Inhibition of chymotrypsin-and subtilisin-like serine proteases with Tk-serpin from hyperthermophilic archaeon Thermococcu skodakaraensis2011
- Author(s)
  Tanaka, S., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1814 Pages: 299-307
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/2111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis : requirement of a C-terminalβ-jelly roll domain for hyperstability2010
- Author(s)
  Foophow, T., Tanaka, S., Angkawidjaja, C., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  J. Mol. Biol
  
  Volume: 400 Pages: 865-877
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20595040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Subtilisin-like serine protease from hyperthermophilic archaeon Thermococcus kodakaraensis with N-and C-terminal propeptides2010
- Author(s)
  Foophow, T., Tanaka, S., Koga, Y., Takano, K., Kanava, S.
- Journal Title
  
  Protein Eng.Des.Sel.
  
  Volume: 23 Pages: 347-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Crystal structure of a subtilisin homologue, Tk-SP from Ther mococcus kodakaraensis : requirement of a C-terminal β-jelly roll domain for hyperstability.2010
- Author(s)
  Foophow, T., Tanaka, S., An gkawidjaja, C., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  J.Mol.Biol.
  
  Volume: 400 Pages: 865-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Sybtukusub-like serine protease from hyperthermophilic archaeon Thermococcus kodakaraensis with N- and C-terminal propeptides.2010
- Author(s)
  Foophow, T., Tanaka, S., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  Protein Eng.Des.Sel. Web掲載(doi : 10. 1093/protein/gzp092)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Requirement of a unique Ca2+-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon.2009
- Author(s)
  Takeuchi, Y., Tanaka, S., matsumura, H., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  Biochemistry 48
  
  Pages: 10637-10643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Requirement of a unique Ca^<2+>-binding loop for folding of Tk-subtilisin from a hyperthermophilic archaeon2009
- Author(s)
  Takeuchi, Y., Tanaka, S., Matsumura, H., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  Biochemistry
  
  Volume: 48 Pages: 10637-10643
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19813760
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin.2009
- Author(s)
  Tanaka, S., Matsumura, H., Koga, Y., Takano, K., Kanaya, S.
- Journal Title
  
  J.Mol.Biol. 394
  
  Pages: 306-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] Identification of the interactions critical for propeptide-catalyzed folding of Tk-subtilisin2009
- Author(s)
  Tanaka, S., Matsumura, H., Koga, Y., Takano, K., and Kanaya, S.
- Journal Title
  
  J. Mol. Biol
  
  Volume: 394 Pages: 306-319
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19766655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21380065
[Journal Article] 酵素の機能改変における結晶構造の役割2008
- Author(s)
  古賀雄一、中野秀雄
- Journal Title
  
  蛋白質結晶の新展開
  
  Pages: 251-261
- Data Source
  KAKENHI-PROJECT-19780075
[Patent] プロテアーゼの製造方法、並びにプロテアーゼ溶液およびプロテアーゼのプロ体溶液2009
- Inventor(s)
  金谷茂則、田中俊一、竹内勇希、高野和文、古賀雄一
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-08-21
- Overseas
- Data Source
  KAKENHI-PROJECT-21380065
[Patent] 新規なプロテアーゼおよびその利用2009
- Inventor(s)
  金谷茂則、チタフーパオ、高野和文、古賀雄一
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-07-30
- Data Source
  KAKENHI-PROJECT-21380065
[Patent] 新規なプロテアーゼおにびその利用2009
- Inventor(s)
  金谷茂則、チタフーパオ、高野和文、古賀雄一
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-07-30
- Overseas
- Data Source
  KAKENHI-PROJECT-21380065
[Patent] プロテアーゼの製造方法、並びにプロテアーゼ溶液およびプロテアーゼのプロ体溶液2009
- Inventor(s)
  金谷茂則、田中俊一、竹内勇希、高野和文、古賀雄一
- Industrial Property Rights Holder
  大阪大学
- Filing Date
  2009-08-21
- Overseas
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Protein trans-splicingを利用した耐熱性プロテアーゼ再構成の検討2019
- Author(s)
  巽祐介,山野-足立範子, 古賀雄一, 大政健史
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19K05827
[Presentation] Novel application of proteins from hyperthermophiles2019
- Author(s)
  古賀雄一
- Organizer
  Thai society of biotechnology 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K05827
[Presentation] 有機溶媒中におけるTk-subtilisinの酵素活性の解析2019
- Author(s)
  宮田大暉, 山野-足立範子, 古賀雄一, 大政健史
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19K05827
[Presentation] 超好熱古細菌（始原菌）由来プロテアーゼ（Tk-SP)のProペプチドが成熟化に与える影響2019
- Author(s)
  長尾征秀, 前川大樹, 山野-足立範子, 古賀雄一, 大政健史
- Organizer
  第71回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19K05827
[Presentation] Subtilisin-like proteases from a hyper-thermophilic archaeon and their application2017
- Author(s)
  古賀雄一
- Organizer
  BIOTEC-OSAKA Univ. Special Seminar
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] 超好熱古細菌由来プロテアーゼTk0076の成熟化機構解明を目指したプロペプチドの探索2017
- Author(s)
  田口萌恵、大政健史、古賀雄一
- Organizer
  第17回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] 超好熱菌由来酵素の構造機能相関研究とその応用2017
- Author(s)
  古賀雄一
- Organizer
  第69回日本生物工学会大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] Construction of large-scale expression system by suppressing the maturation of Tk-SP from hyperthermophilic archaeon2017
- Author(s)
  前川大樹、古賀雄一、大政　健史
- Organizer
  第49回化学工学会秋季大会
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] Protein engineering on a Subtilisin-like protease from a hyper-thermophilic archaeon2017
- Author(s)
  古賀雄一
- Organizer
  The 29th Annual Meeting of the Thai Society for Biotechnology and International Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] 生物資源を活用した研究事例2017
- Author(s)
  古賀雄一
- Organizer
  生物資源活用の世界展開～グローカルバイオテクノロジー～シンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] 超好熱菌由来Thermococcus kodakarensis KOD1 由来subtilisin 様プロテアーゼとその利用2017
- Author(s)
  古賀雄一、清水七海、足立航平、大政健史
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] βサンドイッチドメインを用いた結合分子骨格の検討2017
- Author(s)
  来住秀憲、杉田慎之介、大政健史、古賀雄一
- Organizer
  第17回日本蛋白質科学会
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] ケラチン分解酵素の機能不明C末端ドメインの機能解析2016
- Author(s)
  杉田愼之助、大政健史、古賀雄一
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] Construction of a Novel Expression System of Toxic Protease from a Hyperthermophilic Archaeon Thermococcus kodakararensis KOD12016
- Author(s)
  Daiki Maegawa1, Kohei Adachi1, Takeshi Omasa1, Yuichi Koga
- Organizer
  Extremophiles 2016
- Place of Presentation
  京都大学
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] Hyper-Thermophilic Subtilisin-like Proteases from Thermococcus kodakarensis and Their Application2016
- Author(s)
  Yuichi Koga, Ryo Uehara, Kazufumi Takano
- Organizer
  Extremophiles 2016
- Place of Presentation
  京都大学
- Year and Date
  2016-09-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] Intein を利用した超好熱菌由来プロテアーゼ（Tk-SP）の発現系構築2016
- Author(s)
  足立航平、上原了、Tannous E. Antonios、大政健史、古賀雄一
- Organizer
  日本農芸化学会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K07392
[Presentation] 超好熱古細菌（始原菌）Thermococcus kodakarensis KOD1由来glycerophosphodiester phosphodiesteraseの機能解析2013
- Author(s)
  熱田侑也, 古賀雄一, 小林淳, 劉東周, 佐藤喬章, 跡見晴幸, 金谷茂則
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] Characteristic analysis of compatible solute and production system from G3P in Thermococcus kodakarensis2013
- Author(s)
  鈴木誠志,古賀雄一,金谷茂則
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] Thermococcus kodakarensisにおけるG3Pを出発物質とした適合溶質とその生産系の特性解析2013
- Author(s)
  鈴木誠志, 古賀雄一,金谷茂則
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] Ca2+結合部位の変異による超好熱菌由来セリンプロテアーゼTk-SPの安定化2013
- Author(s)
  三浦明子、洪遜、阿部一勝、Tita Foophow、古賀雄一、金谷茂則
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱古細菌 Thermococcus kodakarensis由来 glycerol-3-phosphate dehydrogenaseの機能解析2013
- Author(s)
  小西香菜子,古賀雄一,小林淳,佐藤喬章,跡見晴幸,金谷茂則
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] Evolvability of thermophilic proteins from archaea and bacteria2013
- Author(s)
  Kazufumi Takano, Atsushi Aoi, Yuichi Koga, Shigenori Kanaya
- Organizer
  Thermophiles 2013
- Place of Presentation
  レゲンスブルグ、ドイツ
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱古細菌Thermococcus kodakarensis由来glycerol-3-phosphate dehydrogenase の機能解析2013
- Author(s)
  小西香菜子, 古賀雄一, 小林淳, 佐藤喬章, 跡見晴幸, 金谷茂則
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] 超好熱菌由来セリンプロテアーゼTk-SPの安定性：活性部位の水素結合の重要性2013
- Author(s)
  阿部一勝、古賀雄一、金谷茂則
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱古細菌(始原菌) Thermococcus kodakarensis KOD1由来 glycerophosphodiester phosphodiesterasの機能解析2013
- Author(s)
  熱田侑也,古賀雄一,小林淳,劉東周,佐藤喬章,跡見晴幸,金谷茂則
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-25660056
[Presentation] Characterization of novel metagenome-derived esterase and cutinase from leaf- branch compost2013
- Author(s)
  Hiroyuki Okano, Sintawee Sulaiman, Eiko kanaya, Dong-Ju You, Yuichi Koga, and Shigenori Kanaya
- Organizer
  5th Congress of the European Microbiologists (FEMS 2013)
- Place of Presentation
  ライプチヒ、ドイツ
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Isolation of novel cellulolytic enzymes from leaf-branch compost by a metagenomic approach2013
- Author(s)
  Masashi Ozaki, Eiko kanaya, Hiroyuki Okano, Yuichi Koga, and Shigenori Kanaya
- Organizer
  5th Congress of the European Microbiologists (FEMS 2013)
- Place of Presentation
  ライプチヒ、ドイツ
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Thermal adaptation of Tk-subtilisin from a hyperthermophilic archaeon2013
- Author(s)
  Ryo Uehara, Yuichi Koga, Shigenori Kanaya
- Organizer
  SeleCa Symposium
- Place of Presentation
  アーヘン、ドイツ
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 基質結合部位への変異導入によるLC-cutinaseの機能改変2013
- Author(s)
  森数渉、Sintawee Sulaiman、金谷栄子、古賀雄一、金谷茂則
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Role of disulfide bond in stability and activity of metagenome-derived LC-cutinase with PET degrading activity2013
- Author(s)
  Sintawee Sulaiman, Dong Ju You, Eiko Kanaya, Yuichi Koga, and Shigenori Kanaya
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] アミノ酸変異によるタンパク質安定化の部位依存性の評価2013
- Author(s)
  田所高志、風間洋隆、古賀雄一、高野和文、金谷茂則
- Organizer
  第１３回日本蛋白質科学会
- Place of Presentation
  とりぎん文化会館、鳥取
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] メタゲノム法により枝葉コンポストから単離した新規セルラーゼの構造機能解析2013
- Author(s)
  Hiroyuki Okano, Eiko Kanaya, Masashi Ozaki, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱古細菌由来Tk-subtilisin の高効率成熟化法の開発2013
- Author(s)
  勇崎孝太、上原了、古賀雄一、金谷茂則
- Organizer
  第36回日本分子生物会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Isolation of LC-cutinase with PET-Degrading Activity from Leaf-branch Compost using a Metagenomic Approach2012
- Author(s)
  Sintawee SVLAIMAN, Saya YAMATO, Dong-Ju YOU, Eiko KANAYA, Yuichi KOGA, and Shigenori KANAYA
- Organizer
  第64回日本生物工学会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Degradation of abnormal prion protein by a hyper-stable protease2012
- Author(s)
  Yuki Hori, Azumi Hirata, Yuichi Koga, Akikazu Sakudo, Kazuyoshi Ikuta, Shigenori Kanaya, and Kazufumi Takano
- Organizer
  Prion 2012
- Place of Presentation
  アムステルダム、オランダ
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱菌由来プロテアーゼTk-subtilisinのCa2+依存性耐熱化機構2012
- Author(s)
  上原了、竹内勇希、田中俊一、高野和文、古賀雄一、金谷茂則
- Organizer
  第64回日本生物工学会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] プロペプチドの改変によるTk-subtilisinの成熟化速度の促進2012
- Author(s)
  勇崎孝太、上原了、三田雄大、古賀雄一、金谷茂則
- Organizer
  第64回日本生物工学会
- Place of Presentation
  神戸国際会議場、神戸
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Structural analysis of the glycerol kinase from a hyperthermophilic archaeon Thermococcus kodakarensis KOD12012
- Author(s)
  古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
- Organizer
  日本農芸化学会年次大会
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] Proteolysis of PrPSc with a thermostable protease and the analysis of its infectivity2012
- Author(s)
  Yuichi Koga, Shunichi Tanaka, Akikazu Sakudo, Azumi Hirata, Kazufumi Takano, Kazuyoshi Ikuta, Shigenori Kanaya
- Organizer
  Asian Pacific Prion Symposium (APPS) 2012
- Place of Presentation
  パシフィコ横浜、横浜
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Tk-subtilisinによる異常型プリオンタンパク質分解効果の生物学的検討2012
- Author(s)
  平田あずみ、古賀雄一、田中俊一、作道章一、生田和良、金谷茂則、高野和文
- Organizer
  第23回日本生体防御学会総会
- Place of Presentation
  品川区総合区民会館、東京
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Structural analysis of the hexameric structure of glycerol kinase from a hyperthermophilic archaeon Thermococcus kodakarensis KOD12011
- Author(s)
  古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
- Organizer
  日本生物工学会
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] 異常プリオン蛋白質(PrPSc)の超好熱菌由来プロテアーゼによる分解2011
- Author(s)
  古賀雄一、田中俊一、作道章一、高野和文、金谷茂則
- Organizer
  第38回日本防菌防黴学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府豊中市)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] An alternative mature form of subtilisin homologue, Tk-SP, from Ther mococcus kodakaraensis identified in the presence of Ca2+2011
- Author(s)
  Nitat Sinsereekul, Tita Foophow, Mai Yamanouchi, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Role of the Ca2+ ions for stability of subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis2011
- Author(s)
  Nitat Sinsereekul, Tita Foophow, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱始原菌(古細菌)由来glycerol kinaseにおける特異な六量体構造の構造と機能2011
- Author(s)
  古賀雄一, 外尾竜太, 勝見亮太, 高野和文, 金谷茂則
- Organizer
  第63回日本生物工学会大会
- Place of Presentation
  東京
- Year and Date
  2011-09-27
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] Thermococcus kodakaraensis由来プロテアーゼTk2168の構造機能解析2011
- Author(s)
  大田黒晴樹、平田あずみ、中堀美賀子、田中俊一、古賀雄一、高野和文、金谷茂則
- Organizer
  第84回日本生化学会
- Place of Presentation
  国立京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱古細菌(始原菌)Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2011
- Author(s)
  小林淳, 古賀雄一, 高野和文, 金谷茂則
- Organizer
  第63回日本生物工学会大会
- Place of Presentation
  東京
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] Enzymatic degradation of PrPSc with a hyperthermstable protease2011
- Author(s)
  Yuichi Koga, Haruki Otaguro, Mutsuo Aranishi, Kouta Yuzaki, Shun-ichi Tanaka, Akikazu Sakudo, Kazufumi Takano, Shigenori Kanaya
- Organizer
  Asian Pacific Prion Symposium (APPS) 2011
- Place of Presentation
  ホテルマロウド軽井沢(長野県北佐久郡軽井沢町)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Mechanism for Accelerating Maturation of Pro-Tk-subtilisin with the Mutation at the C-terminus of Propeptide2011
- Author(s)
  Ryo Uehara, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya
- Organizer
  The 2nd SeleCa Minisymposium
- Place of Presentation
  RWTH Aachen, Germany
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱性プロテアーゼTk-subtilisinの成熟化速度制御2011
- Author(s)
  上原了、田中俊一、古賀雄一、高野和文、金谷茂則
- Organizer
  第11回日本蛋白質科学会
- Place of Presentation
  ホテル阪急エキスポパーク(大阪)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱菌由来Tk-subtilisinの耐熱化機構2011
- Author(s)
  上原了、田中俊一、古賀雄一、高野和文、金谷茂則
- Organizer
  農芸化学会関西支部第469回講演会
- Place of Presentation
  京都府立大学合同講義棟(京都)
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱性プロテアーゼTk-subtilisinの成熟化加速機構の解析2011
- Author(s)
  上原了、上田泰徳、古賀雄一, 高野和文, 金谷茂則
- Organizer
  第63回日本生物工学会
- Place of Presentation
  東京農工大(東京都小金井市)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Accelerated maturation of Tk-subtilisin by the mutation at the C-terminus of propeptide2011
- Author(s)
  Ryo Uehara, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya
- Organizer
  第11回GCOE国際会議
- Place of Presentation
  阪大吹田キャンパス銀杏会館(大阪)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Tk-subtilisinの成熟化における安定化機構2010
- Author(s)
  上原了, 田中俊一, 古賀雄一, 高野和文, 金谷茂則
- Organizer
  日本生物工学会
- Place of Presentation
  フェニックス・シーガイア・リゾート、宮崎
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱始原菌由来サチライシンの成熟化における挿入配列の役割2010
- Author(s)
  上原了, 田中俊一, 古賀雄一, 高野和文, 金谷茂則
- Organizer
  日本分子生物学会・生化学会合同年会
- Place of Presentation
  神戸国際会議場、神戸市
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱始原菌由来サチライシンの成熟化における挿入配列の役割2010
- Author(s)
  上原了, 田中俊一, 古賀雄一, 高野和文, 金谷茂則
- Organizer
  第5回産業用酵素シンポジウム
- Place of Presentation
  長浜
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱古細菌(始原菌)Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2010
- Author(s)
  小林淳、古賀雄一、高野和文、金谷茂則
- Organizer
  日本生物工学会
- Place of Presentation
  宮崎県(宮崎市)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] 超好熱菌由来プロテアーゼによる異常プリオン蛋白質分解2010
- Author(s)
  古賀雄一, 田中俊一, 作道章一, 高野和文, 金谷茂則
- Organizer
  日本生物工学会
- Place of Presentation
  フェニックス・シーガイア・リゾート、宮崎
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Degradation of abnormal prion protein by a new protease from a hyperthermophile2010
- Author(s)
  Yuichi Koga, Shun-ichi Tanaka, Akikazu Sakudo, Kazuyoshi Ikuta, Kazufumi Takano, Shigenori Kanaya
- Organizer
  PRION 2010
- Place of Presentation
  Salzburg, Austria
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Degradation of abnormal prion protein by a new protease from a hyperthermophile2010
- Author(s)
  Yuichi Koga, Shun-ichi Tanaka, Akikazu Sakudo, Kazuyoshi Ikuta, Kazufumi Takano, and Shigenori Kanaya.
- Organizer
  PRION 2010
- Place of Presentation
  Salzburg(Austria)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱古細菌(始原菌) Thermococcus kodakaraensis KOD1由来のglycerol-3-phosphate dehydrogenaseの特性解析2010
- Author(s)
  小林淳, 古賀雄一, 高野和文, 金谷茂則
- Organizer
  日本生物工学会
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-22780091
[Presentation] 超好熱古細菌由来セリンプロテアーゼTk-SP65の特性解析2010
- Author(s)
  平田あずみ、中堀美賀子、田中俊一、古賀雄一、高穿和文、金谷茂則
- Organizer
  日本分子生物学会・生化学会合同年会
- Place of Presentation
  神戸国際会議場、神戸市
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 超好熱菌由来プロテアーゼによる異常プリオン蛋白質分解2010
- Author(s)
  古賀雄一、田中俊一、作道章一、高野和文、金谷茂則
- Organizer
  日本生物工学会
- Place of Presentation
  フェニックス・シーガイア・リゾート(宮崎)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Studies on the maturation process of subtilisin-like serine protease, Tk-SP, from hyperthermophilic archaeon Thermococcus kodakaraensis2010
- Author(s)
  Nitat Sinsereekul, Tita Foophow, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya
- Organizer
  日本分子生物学会・生化学会合同年会
- Place of Presentation
  神戸国際会議場、神戸市
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] 高アルカリ性、高温でのTk-subtilisinの成熟化促進機構の解析2009
- Author(s)
  上田泰徳、田中俊一、古賀雄一、高野和文、金谷茂則
- Organizer
  日本生化学会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Crystal structure of a subtilisin homologue, Tk-SP, from Thermococcus kodakaraensis with a C-terminal jelly roll β-barrel domain2009
- Author(s)
  Tita Foophow, Shun-ichi Tanaka, Clement Angkawidjaja, Yuichi Koga, Kazufumi Takano, Shigenori Kanaya.
- Organizer
  日本生化学会
- Place of Presentation
  神戸国際会議場(神戸市)
- Data Source
  KAKENHI-PROJECT-21380065
[Presentation] Ca2+結合部位の変異による超好熱菌由来セリンプロテアーゼTk-SPの安定化
- Author(s)
  三浦　明子、洪遜、阿部一勝、Tita Foophow、古賀雄一、金谷茂則
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱菌由来プロテアーゼによるプリオンタンパク質分解の評価
- Author(s)
  古賀雄一, 清水七海, 作道章一, 原　英之,　坂口末廣, 金谷茂則
- Organizer
  第66回日本生物工会
- Place of Presentation
  札幌コンベンションセンター、札幌
- Year and Date
  2014-09-09 – 2014-09-11
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 超好熱菌由来プロテアーゼによるプリオン蛋白質分解の評価
- Author(s)
  清水七海, 古賀雄一, 作道章一, 原　英之, 坂口末廣, 金谷茂則
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Proteolysis of abnormal prion protein with a thermostable protease from a hyper-thermophilic archaeon Thermococcus kodakarensis KOD1
- Author(s)
  Yuichi Koga, Nami Shimizu, Akikazu Sakudo, and Shigenori Kanaya
- Organizer
  59th Annual Meeting of Biophysical Society
- Place of Presentation
  ボルティモア、アメリカ
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] 枝葉コンポストから単離したグリコシドヒドロラーゼファミリー12セルラーゼの結晶構造と熱安定化機構に関する研究
- Author(s)
  岡野啓志, 金谷栄子, 尾崎昌史, Angkawidjaja Clement,　古賀雄一, 金谷茂則
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] ベトナムDongNai 川流域のメタゲノムライブラリからの酵素探索
- Author(s)
  藤澤　裕紀、古賀　雄一、Le Phi Nga、金谷　茂則
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館、京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24380055
[Presentation] Crystal structure of glycoside hydrolase family 9 endoglucanase with an N-terminal Ig-like domain isolated from leaf-branch compost
- Author(s)
  Hiroyuki Okano, Eiko kanaya, Masashi Ozaki, Clement Angkawidjaja, Yuichi Koga, and Shigenori Kanaya
- Organizer
  59th Annual Meeting of Biophysical Society
- Place of Presentation
  ボルティモア、アメリカ
- Year and Date
  2015-02-07 – 2015-02-11
- Data Source
  KAKENHI-PROJECT-24380055

1. KANAYA Shigenori (30273585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 77 results
2. CLEMENT Angkawidjaja (20505987)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. KANAYA Eiko (80396217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 45 results
4. SAKUDO Akikazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 上原了

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 松村浩由

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. 田中俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 吉澤拓也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高野和文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koga Yuichi 古賀 雄一

KOGA Yuichi 古賀 雄一

KOGA Yuuichi 古賀 雄一

Research Projects

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Co-Researchers

Development of binding scaffold with a protein from a hyperthermophilic archaeonPrincipal Investigator

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Analysis of abnormal prion protein core structure by proteolysis at high temperaturePrincipal Investigator

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Comprehensive analysis of glycerol metabolism in archaeaPrincipal Investigator

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Development of a technology to degrade, remove or process persistent proteins with enzymes

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Studies on glycerol metabolism of hyperthermophilic arhaeaPrincipal Investigator

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Elucidation of the maturation mechanism of subtilisins from hyperthermophiles and development of their potential use

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Thermodynamic analysis of chiral molecule recognition of enzymesPrincipal Investigator

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[Book] Biotechnology of Microbial Enzymes, production, biocatalysis and industrial applications2016

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[Journal Article] Insertion loop‐mediated folding propagation governs efficient maturation of hyperthermophilic Tk‐subtilisin at high temperatures2021

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[Journal Article] Production of monoclonal shark-derived immunoglobulin new antigen receptor antibodies using Chinese hamster ovary cell expression system2021

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[Journal Article] Affinity shift of ATP upon glycerol binding to a glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakarensis KOD12020

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[Journal Article] Anaerobic glycerol-3-phosphate dehydrogenase complex from hyperthermophilic archaeon Thermococcus kodakarensis KOD12019

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[Journal Article] Effects of Surfactant and a Hyperthermostable Protease on Infectivity of Scrapie-Infected Mouse Brain Homogenate.2015

Koga Yuichi 古賀雄一

KOGA Yuichi 古賀雄一

KOGA Yuuichi 古賀雄一