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ARAI Yoshifumi  新井 義文

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新井 義文  アライ ヨシフミ

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Researcher Number 30381784
Other IDs
Affiliation (based on the past Project Information) *help 2009 – 2013: Hamamatsu University School of Medicine, 医学部, 助教
2005 – 2006: 名古屋市立大学, 大学院医学研究科, 助手
Review Section/Research Field
Principal Investigator
Experimental pathology
Except Principal Investigator
Experimental pathology
Keywords
Principal Investigator
ウイルス性難聴 / サイトメガロウイルス / 発生病理 / 神経細胞培養 / toll-like receptors / ミクログリア / 脳腫瘍
Except Principal Investigator
サイトメガロウイルス / ES細胞 / レセプター … More / 大脳 / β1 インテグリン / iPS / ES / アポトーシス / 興奮毒性細胞死 / ネクローシス / 神経細胞死 / 脳発達障害 / 神経細胞 / ウイルス感染症 / 発生病理 Less
  • Research Projects

    (4 results)
  • Research Products

    (46 results)
  • Co-Researchers

    (4 People)
  •  The analysis of the new inhibitory factor for cytomegalovirus in ES/iPS cells

    • Principal Investigator
      KAWASAKI Hideya
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Pathogenesis of viral infection-induced hearing loss in the developing mouse modelPrincipal Investigator

    • Principal Investigator
      ARAI Yoshifumi
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Hamamatsu University School of Medicine
  •  A study of the participation of viral anti-apoptotic factor in the pathogenesis of developmental brain disorders induced by viral infection

    • Principal Investigator
      KOSUGI Isao
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Hamamatsu University School of Medicine
  •  脳腫瘍発生時におけるミクログリアを中心とする脳内免疫機構の解析Principal Investigator

    • Principal Investigator
      新井 義文
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Nagoya City University

All 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Establishment of a novel mouse model of ulcerative colitis with concomitant cytomegalovirus infection - in vivo identification of cytomegalovirus persistent infected cells,2013

    • Author(s)
      Matsumura K, Nakase H, Kosugi I, Honzawa Y, Yoshino T, Matsuura M, Kawasaki H, Arai Y, Iwashita T, Nagasawa T, Chiba T.
    • Journal Title

      Inflammatory Bowel Disease

      Volume: 19 Pages: 1951-1956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Direct isolation of myofibroblasts and fibroblasts from bleomycin-injured lungs reveals their functional similarities and differences.2013

    • Author(s)
      Akamatsu T, Arai Y, Kosugi I, Kawasaki H, Meguro S, Sakao M, Shibata K, Suda T, Chida K, Iwashita T
    • Journal Title

      Fibrogenesis Tissue Repair

      Volume: 6 Issue: 1 Pages: 15-15

    • DOI

      10.1186/1755-1536-6-15

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Establishment of a novel mouse model of ulcerative colitis with concomitant cytomegalovirus infection - in vivo identification of cytomegalovirus persistent infected cells2013

    • Author(s)
      Matsumura K, Nakase H, Kosugi I, Honzawa Y, Yoshino T, Matsuura M, Kawasaki H, Arai Y, Iwashita T, Nagasawa T, Chiba T
    • Journal Title

      Inflammatory Bowel Disease

      Volume: 19(9) Pages: 1951-1956

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Effect of intrapulmonary viral tropism and cytokine expression on histoligical patterns of cytomegalovirus infection2012

    • Author(s)
      Arai Y, Tsuchida T, Kosugi K, Kawasaki H, Meguro S, Kinoshita M, Baba B, Maeda , Shinmura Y, Tsutsui Y. Iwashita T
    • Journal Title

      Pathology International

      Volume: 62 Issue: 9 Pages: 628-639

    • DOI

      10.1111/j.1440-1827.2012.02849.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22500483, KAKENHI-PROJECT-22590357, KAKENHI-PROJECT-23590445
  • [Journal Article] Effects of intrapulmonary viral tropism and cytokine expression on the histological patterns of cytomegalovirus pneumonia2012

    • Author(s)
      Arai Y, Tsuchida T, Kosugi I, Kawasaki H, Meguro S, Kinoshita M, Baba S, Maeda M, Shinmura Y, Tsutsui Y, Iwashita T
    • Journal Title

      Pathol Int

      Volume: 62 Pages: 628-639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process.2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y.
    • Journal Title

      PloS One

      Volume: 2;6(3)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Mouse Embryonic Stem Cells Inhibit Murine Cytomegalovirus Infection through a Multi-Step Process2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y.
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Mouse Embryonic Stem Cells Inhibit Marine Cytomegalovirus Infection through a Multi-Step Process.2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y.
    • Journal Title

      PLoS One 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Mouse embryonic stem cells inhibit murine cytomegalovirus infection through a multi-step process2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y
    • Journal Title

      PLoS One

      Volume: 6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Journal Article] Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin.2010

    • Author(s)
      Kawasaki, H., Ogura, H., Arai, Y., Baba, S., Kosugi I., et al.
    • Journal Title

      Pathol Int 60

      Pages: 228-234

    • NAID

      10029331202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice.2010

    • Author(s)
      Yamada, S., Kosugi I., Katano, H, Fukui, Y., Kawasaki, H., Arai, Y., Kcrane, I., Inoue, N.
    • Journal Title

      Antiviral Res 88

      Pages: 45-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice2010

    • Author(s)
      Yamada, S., Kosugi, I., Katano, H., Fukui, Y., Kawasaki, H., Arai, Y., Kurane, I., Inoue, N
    • Journal Title

      Antiviral Res

      Volume: 88 Pages: 45-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin2010

    • Author(s)
      Kawasaki, H., Ogura, H., Arai, Y., Baba, S., Kosugi, I., et al.
    • Journal Title

      Pathol Int

      Volume: 60 Pages: 228-234

    • NAID

      10029331202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Aggressive progression of breast cancer with microscopic pulmonary emboli possessing a stem cell-like phenotype independent of its origin2010

    • Author(s)
      Kawasaki H, Ogura H, Arai Y, Baba S, Kosugi I, Tsutsui Y, Iwashita T.
    • Journal Title

      Pathology International 60

      Pages: 228-34

    • NAID

      10029331202

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models.2008

    • Author(s)
      Tsutsui Y, Kosugi I, Kawasaki H, Arai Y, Han GP, Li L, Kaneta M
    • Journal Title

      Pathol Iot 58(5)

      Pages: 257-267

    • NAID

      10027376380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide, a model for hearing loss in congenital CMV infection.2008

    • Author(s)
      Li L, Kosugi I, Ilan GP, Kawasaki H, Arai Y, Takeshita T, Tsutsui Y
    • Journal Title

      Lab Invest. 88(7)

      Pages: 722-730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models.2008

    • Author(s)
      Tsutsui Y, Kosugi I, Kawasaki H, Arai Y, Han GP, Li L, Kaneta M.
    • Journal Title

      Pathology International 58

      Pages: 257-67

    • NAID

      10027376380

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Journal Article] Induction of cytomegalovirus-infected labyrinthitis in newborn mice by lipopolysaccharide : a model for hearing loss in congenital CMV infection.2008

    • Author(s)
      Li L, Kosugi I, Han GP, Kawasaki H, Arai Y, Takeshita T, Tsutsui Y.
    • Journal Title

      Laboratory Investigation 88

      Pages: 722-30

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 急性期サイトメガロウイルス大脳感染における血行性/髄腔内感染標的細 胞とintegrinβ1との関係2013

    • Author(s)
      河崎 秀陽、鈴木 万幾子、小杉 伊三夫、新井 義文、筒井 祥博、岩下 寿秀
    • Organizer
      日本病理学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] 日本ウイルス学会2013

    • Author(s)
      河崎 秀陽、鈴木 万幾子、小杉 伊三夫、新井 義文、筒井 祥博、岩下 寿秀
    • Organizer
      急性期サイトメガロウイルス大脳感染における血行性/髄腔内感染標的細胞とi ntegrin β1との関係
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] 急性期サイトメガロウイルス大脳感染における血行性/髄腔内感染標的細胞とintegrinβ1との関係2013

    • Author(s)
      河崎秀陽、鈴木万幾子、小杉伊三夫、新井義文、筒井祥博、岩下寿秀
    • Organizer
      第61回ウイルス学会
    • Place of Presentation
      神戸
    • Year and Date
      2013-11-10
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] 急性期サイトメガロウイルス大脳感染における血行性/髄腔内感染標的細胞とintegrinβ1との関係2013

    • Author(s)
      河崎秀陽、鈴木万幾子、小杉伊三夫、新井義文、筒井祥博、岩下寿秀
    • Organizer
      第102回日本病理学会
    • Place of Presentation
      札幌
    • Year and Date
      2013-06-06
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] サイトメガロウイルス大脳急性感染期におけるintegrin β1発現と感染分布との関係2012

    • Author(s)
      河崎 秀陽, 小杉 伊三夫, 鈴木 万幾子, 新井 義文, 筒井 祥博, 岩下 寿秀
    • Organizer
      第52回日本先天異常学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] サイトメガロウイルス大脳急性感染期におけるintegrinβ1発現と感染分布2012

    • Author(s)
      河崎秀陽、小杉伊三夫、鈴木万幾子、新井義文、筒井祥博、岩下寿秀
    • Organizer
      第52回日本先天異常学会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-06
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] サイトメガロウイルス大脳急性感染期におけるintegrinβ1発現と感染分布2012

    • Author(s)
      河崎秀陽、小杉伊三夫、新井義文、筒井祥博、岩下寿秀
    • Organizer
      第101会日本病理学会
    • Place of Presentation
      東京
    • Year and Date
      2012-04-26
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] サイトメガロウイルス大脳急性感染期におけるintegrin β1発現と感染分布2012

    • Author(s)
      河崎 秀陽, 小杉 伊三夫, 新井 義文, 筒井 祥博, 岩下 寿秀
    • Organizer
      第101会日本病理学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] MOUSE EMBRYONIC STEM CELLS INHIBIT MURINE CYTOMEGALOVIRUS INFECTION THROUGH A MULTI-STEP PROCESS2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y.
    • Organizer
      International Congress of Virology
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] Mouse Embryonic Stem Cells inhibit Cyotomegalovirus Infection Through a Multi-Step Process2011

    • Author(s)
      Kawasaki H, Kosugi I, Arai Y, Iwashita T, Tsutsui Y
    • Organizer
      International Congress of Virology
    • Place of Presentation
      Sapporo
    • Year and Date
      2011-09-15
    • Data Source
      KAKENHI-PROJECT-23590445
  • [Presentation] In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice2010

    • Author(s)
      Yamada, S., Kosugi I., Katano, H., Fukui, Y. , Kawasaki, H., Arai, Y., Kurane, I., N.Inoue.
    • Organizer
      2010 Congenital Cytomegalovirus Conference
    • Place of Presentation
      France
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育期大脳神経細胞におけるサイトメガロウイルス感染と脳発達障害2010

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 岩下寿秀, 筒井祥博
    • Organizer
      第58回日本ウイルス学会学術集会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] ES細胞におけるサイトメガロウイルス感染感受性の多段階的制御とその機序2010

    • Author(s)
      河崎秀陽, 小杉伊三夫, 新井義文, 岩下寿秀、筒井祥博
    • Organizer
      第99回日本病理学会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-28
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] GFP発現組換えマウスサイトメガロウイルスを用いたin vivo imagingによる抗ヘルペスウイルス薬in vivo評価系の確立2010

    • Author(s)
      山田壮一、小杉伊三夫、片野晴隆、福井良子、河崎秀陽、新井義文、福地早紀、橋本楓、倉根一郎、井上直樹
    • Organizer
      第25回ヘルペスウイルス研究会
    • Place of Presentation
      浜松
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育脳神経細胞におけるサイトメガロウイルス感染と脳発達障害:感染神経細胞における樹状突起の解析2010

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 岩下寿秀, 筒井祥博
    • Organizer
      第99回日本病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-28
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] Bacterial artificial chromosomeを用いた組織標本中のウイルスゲノム同定法2010

    • Author(s)
      新井義文, 小杉伊三夫, 河崎秀陽, 岩下寿秀, 筒井祥博
    • Organizer
      第99回病理学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-04-28
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] In vivo imaging assay for the convenient evaluation of antiviral compounds against cytomegalovirus in mice2010

    • Author(s)
      Yamada, S., Kosugi, L, Katano, H., Fukui, Y., Kawasaki, H., Arai, Y, Kurane, I., N.Inoue
    • Organizer
      Congenital Cytomegalovirus Conference
    • Place of Presentation
      Paris, France
    • Year and Date
      2010-09-15
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育期大脳神経細胞におけるサイトメガロウイルス感染と脳発達障害2010

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 岩下寿秀, 筒井祥博
    • Organizer
      第25回ヘルペスウイルス研究会
    • Place of Presentation
      浜松
    • Year and Date
      2010-05-27
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] ES細胞におけるサイトメガロウイルス感染感受性の多段階的制御とその機序2010

    • Author(s)
      河崎秀陽、小杉伊三夫、新井義文、岩下寿秀、筒井祥博
    • Organizer
      第50回日本先天異常学会学術集会
    • Place of Presentation
      淡路
    • Year and Date
      2010-07-20
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] サイトメガロウイルス感染モデルマウスを用いた聴覚障害機序の解析2009

    • Author(s)
      生田和史, 小川洋, 大森孝一, 小杉伊三夫, 新井義文, 錫谷達夫
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] Differential activation of murine cytomegalovirus el promoter in neurons during infection of the developing mouse brain and primary neuronal culture2009

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 筒井祥博
    • Organizer
      第12回国際サイトメガロウイルスワークショップ
    • Place of Presentation
      ボストン、米国
    • Year and Date
      2009-05-11
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] Differential activation of murine cytomegalovirus el promoter in neurons during infection of the developing mouse brain and primary neuronal culture2009

    • Author(s)
      Isao Kosugi, Yoshifumi Arai, Hideya Kawasaki, Yoshihiro Tsutsui
    • Organizer
      第12回国際サイトメガロウイルスワークショップ
    • Place of Presentation
      米国
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育脳神経細胞におけるサイトメガロウイルス感染と脳発達障害2009

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 筒井祥博
    • Organizer
      第98回日本病理学会総会
    • Place of Presentation
      京都
    • Year and Date
      2009-05-01
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育期神経細胞におけるサイトメガロウイルス感染と脳発達障害 : 感染神経細胞に特徴的なNF-κB核内局在の解析2009

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 筒井祥博
    • Organizer
      第57回日本ウイルス学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-10-26
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] A unique activation of marine cytomegalovirus el promoter in neurons during the infection of the developing mouse brain and primary neuronal culture2008

    • Author(s)
      Kosugi I, Arai Y, Kawasaki H, Li L, Tsutsui Y
    • Organizer
      第33回国際ヘルペスウイルスワークショップ
    • Place of Presentation
      ポルトガル
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育脳におけるマウスサイトメガロウイルスの臨界期神経細胞に特異的な感染動態2008

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 筒井祥博
    • Organizer
      第56回日本ウイルス学会学術集会
    • Place of Presentation
      岡山市
    • Year and Date
      2008-10-26
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] 発育期脳におけるサイトメガロウイルスの神経細胞特異的な感染動態と脳発達障害2008

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 李立, 筒井祥博
    • Organizer
      第97回日本病理学会総会ワークショップ
    • Place of Presentation
      金沢市
    • Year and Date
      2008-05-17
    • Data Source
      KAKENHI-PROJECT-20590396
  • [Presentation] A unique activation of murine cytomegalovirus el promoter in neurons during the infection of the developing mouse brain and primary neuronal culture2008

    • Author(s)
      小杉伊三夫, 河崎秀陽, 新井義文, 李立, 筒井祥博
    • Organizer
      第33回国際ヘルペスウイルスワークショップ
    • Place of Presentation
      エストリル, ポルトガル
    • Data Source
      KAKENHI-PROJECT-20590396
  • 1.  KOSUGI Isao (10252173)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 45 results
  • 2.  KAWASAKI Hideya (90397381)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 44 results
  • 3.  IWASHITA Toshihide (00283432)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 16 results
  • 4.  TSUTSUI Yoshihiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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