Shibata Norihito 柴田識人

… Alternative Names

柴田識人シバタノリヒト

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Researcher Number	30391973
Other IDs
Affiliation (Current)	2023: 国立医薬品食品衛生研究所, 生化学部, 部長
Affiliation (based on the past Project Information) *help	2019 – 2022: 国立医薬品食品衛生研究所, 生化学部, 室長 2018: 国立医薬品食品衛生研究所, 遺伝子医薬部, 主任研究官 2014 – 2016: 国立医薬品食品衛生研究所, 遺伝子医薬部, 主任研究官 2007: 理研, 研究員 2006: 独立行政法人理化学研究所, 辻本細胞生化学研究室, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Basic Section 43060:System genome science-related
Keywords	Principal Investigator コレステロール生合成 / スクアレンエポキシダーゼ / 絶食 / PPARα / フィブラート系薬剤 / 酸化コレステロール / 脱ユビキチン化酵素 / がん特異的融合タンパク質 / タンパク質分解 / がん … More / 融合キナーゼタンパク質 / ゲノム編集 / Cas9 / タンパク質制御 / ゲノム編集技術 … More Except Principal Investigator ゲノム編集 / DNA２本鎖切断 / CRISPR / 細胞周期 / DNA修復 Less

Development of cell-cycle-regulated CRISPR/Cas system
- Principal Investigator
  
  近藤一成
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  National Institute of Health Sciences
Cas9タンパク質の制御によるCRISPR/Cas9オフターゲット編集の抑制Principal Investigator
- Principal Investigator
  
  柴田識人
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  National Institute of Health Sciences
Development of novel anti-tumor drugs targeting the stability of oncogenic fusion kinase proteinsPrincipal Investigator
- Principal Investigator
  
  Shibata Norihito
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Institute of Health Sciences
Analysis of antiviral activity of 25-hydroxycholesterolPrincipal Investigator
- Principal Investigator
  
  Shibata Norihito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  National Institute of Health Sciences
新規コレステロール代謝調節機構の創薬応用の検討と本機構の持つ新たな生理意義の解明Principal Investigator
- Principal Investigator
  
  柴田識人
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2021 2020 2019 2018 2017 2016 2015 2006 Other

All Journal Article Presentation Patent

[Journal Article] Development of a degrader against oncogenic fusion protein FGFR3-TACC32022
- Author(s)
  Shibata Norihito、Cho Nobuo、Koyama Hiroo、Naito Mikihiko
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 60 Pages: 128584-128584
- DOI
  10.1016/j.bmcl.2022.128584
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07311, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-21K06075
[Journal Article] Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer2021
- Author(s)
  Yokoo Hidetomo、Shibata Norihito、Naganuma Miyako、Murakami Yuki、Fujii Kiyonaga、Ito Takahito、Aritake Kosuke、Naito Mikihiko、Demizu Yosuke
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 12 Pages: 236-241
- DOI
  10.1021/acsmedchemlett.0c00605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07311, KAKENHI-PROJECT-20K22711, KAKENHI-PROJECT-17K08385, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-21K05320
[Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021
- Author(s)
  Yokoo Hidetomo、Shibata Norihito、Endo Akinori、Ito Takahito、Yanase Yuta、Murakami Yuki、Fujii Kiyonaga、Hamamura Kengo、Saeki Yasushi、Naito Mikihiko、Aritake Kosuke、Demizu Yosuke
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 64 Pages: 15868-15882
- DOI
  10.1021/acs.jmedchem.1c01206
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K07311, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05498, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-20K06568, KAKENHI-PROJECT-21K05320, KAKENHI-PROJECT-21K11613, KAKENHI-PROJECT-20K22711
[Journal Article] Strategy for detecting off-target sites in genome-edited rice2021
- Author(s)
  Jumpei Narushima, Shinya Kimata, Yuh Shiwa, Takahiro Gondo, Satoru Akimoto, Keisuke Soga, Satoko Yoshiba, Kosuke Nakamura, Norihito Shibata, Kazunari Kondo
- Journal Title
  
  bioRxiv
  
  Volume: 5/29 Pages: 1-26
- DOI
  10.1101/2021.05.28.446070
- Open Access
- Data Source
  KAKENHI-PROJECT-21H02469, KAKENHI-PROJECT-20K05901
[Journal Article] Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects2021
- Author(s)
  Tsukumo Yoshinori、Tsuji Genichiro、Yokoo Hidetomo、Shibata Norihito、Ohoka Nobumichi、Demizu Yosuke、Naito Mikihiko
- Journal Title
  
  Methods Mol Biol
  
  Volume: 2365 Pages: 331-347
- DOI
  10.1007/978-1-0716-1665-9_18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-18K07311, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-21H02777, KAKENHI-PROJECT-19K07724, KAKENHI-PROJECT-21K05320
[Journal Article] Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.2020
- Author(s)
  Shibata Norihito、Ohoka Nobumichi、Tsuji Genichiro、Demizu Yosuke、Miyawaza Keiji、Ui-Tei Kumiko、Akiyama Tetsu、Naito Mikihiko
- Journal Title
  
  Oncogene
  
  Volume: - Pages: 3867-3878
- DOI
  10.1038/s41388-020-1253-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07311, KAKENHI-PLANNED-17H06325, KAKENHI-PROJECT-17H01537, KAKENHI-PROJECT-17K08385, KAKENHI-PLANNED-18H05502
[Journal Article] 脱ユビキチン化酵素阻害によるプロテインノックダウン2020
- Author(s)
  柴田識人, 内藤幹彦
- Journal Title
  
  実験医学
  
  Volume: 38 Pages: 2337-2341
- Data Source
  KAKENHI-PROJECT-18K07311
[Journal Article] がんに対する核酸医薬品の開発2020
- Author(s)
  井上貴雄, 柴田識人
- Journal Title
  
  がん分子標的治療
  
  Volume: 18 Pages: 78-86
- Data Source
  KAKENHI-PROJECT-18K07311
[Journal Article] Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein2019
- Author(s)
  Shibata Norihito、Ohoka Nobumichi、Hattori Takayuki、Naito Mikihiko
- Journal Title
  
  CHEMICAL & PHARMACEUTICAL BULLETIN
  
  Volume: 67 Issue: 3 Pages: 165-172
- DOI
  10.1248/cpb.c18-00703
- NAID
  130007606378
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06567, KAKENHI-PROJECT-18K07311, KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-16H05090
[Journal Article] 標的蛋白質分解を誘導するハイブリッド化合物SNIPERsとPROTACs．2018
- Author(s)
  柴田識人, 内藤幹彦
- Journal Title
  
  医学のあゆみ
  
  Volume: 267 Pages: 1069-1075
- Data Source
  KAKENHI-PROJECT-18K07311
[Journal Article] Protein Knockdown Technology: Application of Ubiquitin Ligase to Cancer Therapy.2016
- Author(s)
  Ohoka N, Shibata N, Hattori T, Naito M.
- Journal Title
  
  Curr. Cancer Drug Targets.
  
  Volume: 16 Pages: 136-146
- DOI
  10.2174/1568009616666151112122502
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860049, KAKENHI-PROJECT-26860050
[Journal Article] Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand2016
- Author(s)
  Demizu, Y., Shibata, N., Hattori, T., Ohoka, N., Motoi, H., Misawa, T., Shoda, T., Naito, M. & Kurihara, M.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 26 Pages: 1865-4869
- DOI
  10.1016/j.bmcl.2016.09.041
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05090, KAKENHI-PROJECT-26860050, KAKENHI-PROJECT-26860085, KAKENHI-PROJECT-16K08340, KAKENHI-PROJECT-26460169, KAKENHI-PROJECT-16K15121, KAKENHI-PROJECT-16K18916
[Journal Article] Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα.2016
- Author(s)
  K. Okuhira, Y. Demizu, T. Hattori, N. Ohoka, N. Shibata, T. Nishimaki-Mogami, H. Okuda, M. Kurihara, M. Naito*
- Journal Title
  
  Methods Mol Biol
  
  Volume: 1366 Pages: 549-560
- DOI
  10.1007/978-1-4939-3127-9_42
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460169, KAKENHI-PROJECT-26860049, KAKENHI-PROJECT-26860050, KAKENHI-PROJECT-25430164, KAKENHI-PROJECT-16H05090
[Journal Article] Degradation of stop codon read-through mutant proteins via the ubiquitin-proteasome system causes hereditary disorders.2015
- Author(s)
  Shibata N, Ohoka N, Sugaki Y, Onodera C, Inoue M, Sakuraba Y, Takakura D, Hashii N, Kawasaki N, Gondo Y, Naito M
- Journal Title
  
  J. Biol. Chem
  
  Volume: 290 Pages: 28428-28437
- DOI
  10.1074/jbc.m115.670901
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26860050, KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25460084
[Journal Article] Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis2006
- Author(s)
  Norihito Shibata
- Journal Title
  
  The FASEB Journal 20
  
  Pages: 2642-2642
- Data Source
  KAKENHI-PROJECT-18790076
[Patent] 新規化合物及び医薬組成物2020
- Inventor(s)
  出水庸介, 柴田識人, 内藤幹彦, 有竹浩介, 横尾英知
- Industrial Property Rights Holder
  出水庸介, 柴田識人, 内藤幹彦, 有竹浩介, 横尾英知
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-122534
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 造血器型プロスタグランジンD合成酵素選択的タンパク質分解誘導剤の開発2022
- Author(s)
  柴田識人, 横尾英知, 遠藤彬則, 伊藤貴仁, 栁瀨雄太, 村上優貴, 藤井清永, 近藤一成, 佐伯泰, 内藤幹彦, 有竹浩介, 出水庸介
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 造血器型プロスタグランジンD合成酵素選択的タンパク質分解誘導剤の開発2022
- Author(s)
  柴田識人, 横尾英知, 遠藤彬則, 伊藤貴仁, 栁瀨雄太, 村上優貴, 藤井清永, 近藤一成, 佐伯泰, 内藤幹彦, 有竹浩介, 出水庸介
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-21K06075
[Presentation] ヒト細胞TK6を用いたCRISPR/Casによる構造変異(SV)解析の検討2021
- Author(s)
  近藤一成, 成島純平, 曽我慶介, 吉場聡子, 柴田識人, 坂田こずえ, 田口千恵, 加藤怜子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06075
[Presentation] ゲノム編集作物におけるオフターゲット予測法の検討2021
- Author(s)
  成島純平, 木俣真弥, 志波優, 権藤崇裕, 秋元智, 曽我慶介, 吉場聡子, 中村公亮, 柴田識人, 近藤一成
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06075
[Presentation] 造血器型プロスタグランジンD合成酵素を標的とした選択的タンパク質分解誘導剤の開発2021
- Author(s)
  柴田識人, 横尾英知, 遠藤彬則, 伊藤貴仁, 栁瀨雄太, 村上優貴, 藤井清永, 近藤一成, 佐伯泰, 内藤幹彦, 有竹浩介, 出水庸介
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-21K06075
[Presentation] 造血器型プロスタグランジンD合成酵素を標的とした選択的タンパク質分解誘導剤の開発2021
- Author(s)
  柴田識人, 横尾英知, 遠藤彬則, 伊藤貴仁, 栁瀨雄太, 村上優貴, 藤井清永, 近藤一成, 佐伯泰, 内藤幹彦, 有竹浩介, 出水庸介
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] ヒト細胞TK6を用いたCRISPR/Casによる構造変異(SV)解析の検討2021
- Author(s)
  近藤一成、成島純平、曽我慶介、吉場聡子、柴田識人、坂田こずえ、田口千恵、加藤怜子
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02469
[Presentation] 発がん因子BCR-ABLの脱ユビキチン化は慢性骨髄性白血病細胞の増殖に必要である2020
- Author(s)
  柴田識人, 大岡伸通, 辻厳一郎, 出水庸介, 内藤幹彦
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 脱ユビキチン化によるがん特異的融合タンパク質の安定化2020
- Author(s)
  柴田識人, 内藤幹彦
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] A novel strategy for destabilization of oncogenic fusion protein BCR-ABL to inhibit growth of CML.2019
- Author(s)
  Shibata N, Ohoka N, Naito M
- Organizer
  5th International Symposium for Medicinal Sciences, 139th Annual Meeting of the Pharmaceutical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 脱ユビキチン化による発がん因子BCR-ABLのタンパク質安定化2019
- Author(s)
  柴田識人, 大岡伸通, 内藤幹彦
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 脱ユビキチン化による発がん因子BCR-ABLの安定化は慢性骨髄性白血病細胞の増殖を促進する2019
- Author(s)
  柴田識人, 大岡伸通, 内藤幹彦
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 発がん因子BCR-ABLの分解を誘導する２つのアプローチ2019
- Author(s)
  柴田識人, 大岡伸通, 内藤幹彦
- Organizer
  第19回日本蛋白質科学会年会, 第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 脱ユビキチン化によるがん特異的融合タンパク質の安定化2019
- Author(s)
  柴田識人, 大岡伸通, 築茂由則, 内藤幹彦
- Organizer
  新学術領域「ケモユビキチン」第三回班会議
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 発がん因子BCR-ABLのタンパク質分解誘導剤とキナーゼ阻害剤の薬理学的相違2018
- Author(s)
  柴田識人，大岡伸通，服部隆行，内藤幹彦
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] 発がん因子BCR-ABLの蛋白質分解2018
- Author(s)
  柴田　識人
- Organizer
  第２回ユビキチン研究会
- Data Source
  KAKENHI-PROJECT-18K07311
[Presentation] プロテインノックダウン法を利用したアンドロゲン受容体タンパク質分解誘導剤の開発2017
- Author(s)
  柴田識人、永井克典、森田陽子、宇治川治、大岡伸通、服部隆行、今枝泰宏、奈良洋、長展生、内藤幹彦
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] BCR-ABLの蛋白質分解誘導剤開発を指向したBCR-ABL結合化合物の探索2016
- Author(s)
  柴田識人、大岡伸通、服部隆行、橋井則貴、斎藤臣雄、近藤恭光、石井明子、長田裕之、内藤幹彦
- Organizer
  日本薬学会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] 発がん因子BCR-ABLを分解する低分子化合物の開発2016
- Author(s)
  柴田識人、大岡伸通、服部隆行、内藤幹彦
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] 終止コドンリードスルー変異による蛋白質のユビキチン-プロテアソーム依存的な分解はある種の遺伝性疾患の原因となりえる2015
- Author(s)
  柴田識人、大岡伸通、権藤洋一、内藤幹彦
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] 終止コドンのリードスルー変異によるユビキチン-プロテアソーム系を介した蛋白質の不安定化
- Author(s)
  柴田　識人、大岡伸通、権藤　洋一、内藤　幹彦
- Organizer
  日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] 終止コドンのリードスルー変異によるユビキチン-プロテアソーム系を介した蛋白質の不安定化
- Author(s)
  柴田　識人、大岡伸通、櫻庭　喜行、権藤　洋一、内藤　幹彦
- Organizer
  日本薬学会
- Place of Presentation
  デザイン・クリエイティブセンター神戸（兵庫県）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860050
[Presentation] 終止コドンのリードスルー変異によるユビキチン-プロテアソーム系を介した蛋白質の不安定化
- Author(s)
  柴田　識人、大岡伸通、櫻庭　喜行、権藤　洋一、内藤　幹彦
- Organizer
  Symposium for young ubiquitin researchers in Japan“New Era in the Ubiquitin Research”
- Place of Presentation
  国際高等研究所（京都府）
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-26860050

1. 近藤一成 (40270623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 曽我慶介 (50746336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 為広紀正 (80597881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. DEMIZU YOSUKE

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
5. SYODA Takuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. SAEKI Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. TSUKUMO Yosinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
9. 伊藤拓水

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
10. 大岡伸通

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 秋山徹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 服部隆行

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 権藤洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 栗原正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 遠藤彬則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 濱村賢吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 奥平桂一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shibata Norihito 柴田 識人

柴田 識人 シバタ ノリヒト

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Development of cell-cycle-regulated CRISPR/Cas system

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Cas9タンパク質の制御によるCRISPR/Cas9オフターゲット編集の抑制Principal Investigator

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Development of novel anti-tumor drugs targeting the stability of oncogenic fusion kinase proteinsPrincipal Investigator

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Analysis of antiviral activity of 25-hydroxycholesterolPrincipal Investigator

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新規コレステロール代謝調節機構の創薬応用の検討と本機構の持つ新たな生理意義の解明Principal Investigator

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[Journal Article] Development of a degrader against oncogenic fusion protein FGFR3-TACC32022

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[Journal Article] Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer2021

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[Journal Article] Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design2021

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[Journal Article] Strategy for detecting off-target sites in genome-edited rice2021

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[Journal Article] Protocols for Synthesis of SNIPERs and the Methods to Evaluate the Anticancer Effects2021

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[Journal Article] Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.2020

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[Journal Article] 脱ユビキチン化酵素阻害によるプロテインノックダウン2020

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[Journal Article] がんに対する核酸医薬品の開発2020

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[Journal Article] Development of a Potent Protein Degrader against Oncogenic BCR-ABL Protein2019

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Shibata Norihito 柴田識人

柴田識人シバタノリヒト