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Kuma Akiko  久万 亜紀子

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KUMA Akiko  久万 亜紀子

久万 亜紀子  クマ アキコ

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Researcher Number 30392377
Other IDs
External Links
Affiliation (Current) 2025: 大阪大学, 大学院 医学系研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2023 – 2024: 大阪大学, 大学院医学系研究科, 特任准教授(常勤)
2017 – 2021: 大阪大学, 医学系研究科, 特任准教授(常勤)
2016: 東京大学, 大学院医学系研究科(医学部), 助教
2012: 東京医科歯科大学, 医歯(薬)学総合研究科, 助教
2010 – 2012: 東京医科歯科大学, 大学院・医歯学総合研究科, 助教
2006: 東京都医学研究機構, 研究員
2005: (財)東京都医学研究機構, 東京都臨床医学総合研究所, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 44010:Cell biology-related / Pathological medical chemistry / Transformative Research Areas, Section (III) / Biological Sciences / General medical chemistry
Keywords
Principal Investigator
オートファジー / コンタクトサイト / オルガネラ / 小胞体 / タンパク質分解 / リソソーム / 神経疾患 / 神経変性疾患 / 選択的基質 / 生理学 … More / 遺伝子改変マウス / 栄養代謝 / ノックアウトマウス / 細胞内クリアランス / タンパク質凝集体 Less
  • Research Projects

    (7 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (1 People)
  •  リソソーム損傷応答とタンパク質寿命変容Principal Investigator

    • Principal Investigator
      久万 亜紀子
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Osaka University
  •  小胞体連携を基軸としたオートファジー分子機構解析Principal Investigator

    • Principal Investigator
      久万 亜紀子
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Osaka University
  •  Search for Autophagy Regulators by Mass Spectrometry of Autophagy-Deficient Mouse BrainsPrincipal Investigator

    • Principal Investigator
      KUMA AKIKO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Osaka University
  •  The role of autophagy in the maintenance of homeostasis in brainPrincipal Investigator

    • Principal Investigator
      Kuma Akiko
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
      The University of Tokyo
  •  新規モデルマウスによるオートファジーの全身網羅的な解析Principal Investigator

    • Principal Investigator
      久万 亜紀子
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Medical and Dental University
  •  The role of autophagy in nutrient metabolismPrincipal Investigator

    • Principal Investigator
      KUMA Akiko
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Tokyo Medical and Dental University
  •  オートファジーによる細胞内変性タンパク質蓄積の抑制メカニズムPrincipal Investigator

    • Principal Investigator
      久万 亜紀子
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Tokyo Metropolitan Organization for Medical Research

All 2023 2017 2016 2012 2010 2006 2005 Other

All Journal Article Presentation Book

  • [Book] 遺伝子制御の新たな主役 栄養シグナル2016

    • Author(s)
      久万 亜紀子
    • Total Pages
      7
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-16K08613
  • [Journal Article] The TMEM192-mKeima probe specifically assays lysophagy and reveals its initial steps2023

    • Author(s)
      Shima Takayuki、Ogura Monami、Matsuda Ruriko、Nakamura Shuhei、Jin Natsuko、Yoshimori Tamotsu、Kuma Akiko
    • Journal Title

      Journal of Cell Biology

      Volume: 222 Issue: 12

    • DOI

      10.1083/jcb.202204048

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22KJ2105, KAKENHI-PROJECT-23K05764, KAKENHI-PROJECT-21K06160, KAKENHI-PLANNED-21H05145, KAKENHI-PROJECT-22H04982, KAKENHI-PROJECT-21H02428
  • [Journal Article] Autophagy-monitoring and autophagy-deficient mice.2017

    • Author(s)
      Kuma A, Komatsu M, Mizushima N.
    • Journal Title

      Autophagy

      Volume: 13 Issue: 10 Pages: 1619-1628

    • DOI

      10.1080/15548627.2017.1343770

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08613, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111005, KAKENHI-PLANNED-25111006
  • [Journal Article] Transgenic rescue of Atg5-null mice from neonatal lethality with neuron-specific expression of ATG5: Systemic analysis of adult Atg5-deficient mice.2017

    • Author(s)
      Yoshii SR, Kuma A, Mizushima N.
    • Journal Title

      Autophagy

      Volume: 13 Issue: 4 Pages: 763-764

    • DOI

      10.1080/15548627.2017.1280221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08613, KAKENHI-ORGANIZER-25111001, KAKENHI-PLANNED-25111005
  • [Journal Article] Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons.2016

    • Author(s)
      Yoshii SR, Kuma A, Akashi T, Hara T, Yamamoto A, Kurikawa Y, Itakura E, Tsukamoto S, Shitara H, Eishi Y, Mizushima N.
    • Journal Title

      Developmental cell

      Volume: 39 Issue: 1 Pages: 116-130

    • DOI

      10.1016/j.devcel.2016.09.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01194, KAKENHI-PROJECT-15H05637, KAKENHI-PROJECT-16H06167, KAKENHI-PROJECT-16K08613, KAKENHI-PLANNED-25111005, KAKENHI-PROJECT-15K19002
  • [Journal Article] Organelle degradation during the lends and erythroid differentiation is independent of autophagy.2006

    • Author(s)
      Matsui, M., Yamamoto, A., Kuma A., Ohsumi, Y., Mizushima, N
    • Journal Title

      Biochemical and Biophysical Research Communications 339

      Pages: 485-489

    • Data Source
      KAKENHI-PROJECT-17790222
  • [Journal Article] オートファジーによるタンパク質代謝の生埋学的意義2005

    • Author(s)
      水島昇, 久万亜紀子
    • Journal Title

      細胞工学 24

      Pages: 567-571

    • Data Source
      KAKENHI-PROJECT-17790222
  • [Presentation] オルガネラ選択的オートファジーにおける小胞体の役割2023

    • Author(s)
      久万亜紀子
    • Organizer
      第96回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-23K05764
  • [Presentation] Systemic Analysis of Atg5-Null Mice Rescued from Neonatal Lethality by Transgenic ATG5 Expression in Neurons2017

    • Author(s)
      Akiko Kuma, Saori Yoshii, Takumi Akashi, Taichi Hara, Atsushi Yamamoto, Yoshitaka Kurikawa, Eisuke Itakura, Satoshi Tsukamoto, Hiroshi Shitara, Yoshinobu Eishi, Noboru Mizushima
    • Organizer
      Joint Japan-Korea-China Young Investigator Conference
    • Place of Presentation
      Korea
    • Year and Date
      2017-02-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08613
  • [Presentation] Transgenic rescue of <I>Atg5</I>-null mice from neonatal lethality with neuron-specific expression of ATG52017

    • Author(s)
      久万 亜紀子
    • Organizer
      第69回日本細胞生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K08613
  • [Presentation] 神経特異的Atg5レスキューマウスにおけるオートファジーの生理機能解析2012

    • Author(s)
      久万 亜紀子
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場
    • Data Source
      KAKENHI-PROJECT-22790276
  • [Presentation] 神経特異的Atg5レスキューマウスによるオートファジーの生理機能解析2012

    • Author(s)
      久万 亜紀子
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PUBLICLY-23113708
  • [Presentation] オートファジーの生理機能2012

    • Author(s)
      久万 亜紀子
    • Organizer
      日本生体防御学会学術総会
    • Place of Presentation
      品川区総合区民会館キュリアン小ホール
    • Year and Date
      2012-07-10
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-23113708
  • [Presentation] 神経特異的Atg5レスキューマウスにおけるオートファジーの生理機能解析2012

    • Author(s)
      久万亜紀子
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-11
    • Data Source
      KAKENHI-PROJECT-22790276
  • [Presentation] オートファジーの生理機能2012

    • Author(s)
      久万亜紀子
    • Organizer
      第23回日本生体防御学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2012-07-10
    • Data Source
      KAKENHI-PROJECT-22790276
  • [Presentation] Analysis of Atg5-deficient Mice Rescued with Atg5 Expression in the Brain2010

    • Author(s)
      久万亜紀子
    • Organizer
      日本生化学会(BMB2010)
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22790276
  • [Presentation] Analysis of Atg5-deficient mice rescued with Atg espression in the brain.2010

    • Author(s)
      久万亜紀子
    • Organizer
      第83回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22790276
  • [Presentation] オートファジーの生理機能

    • Author(s)
      久万 亜紀子
    • Organizer
      日本生体防御学会学術総会
    • Place of Presentation
      品川区総合区民会館キュリアン小ホール
    • Invited
    • Data Source
      KAKENHI-PROJECT-22790276
  • 1.  板倉 英祐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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