Yukiko Mizutani 水谷有紀子

… Alternative Names

水谷有紀子ミズタニユキコ

MIZUTANI Yukiko 水谷有紀子

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Researcher Number	30396296
Other IDs
Affiliation (Current)	2025: 岐阜薬科大学, 薬学部, 客員准教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 岐阜薬科大学, 薬学部, 特任准教授 2017 – 2022: 岐阜薬科大学, 薬学部, 特任准教授 2011: 名古屋大学, 医学(系)研究科(研究院), 助教 2011: 名古屋大学, 医学系研究科, COE 特任助教 2010: 北海道大学, 大学院・先端生命科学研究院, 特任助教 2007: Hokkaido University, Faculty of Advanced Life Science, Assistant 2006: 大学院先端生命科学研究院, 特任助手
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Structural biochemistry Except Principal Investigator Basic Section 53050:Dermatology-related / Dermatology / Functional biochemistry
Keywords	Principal Investigator 皮膚機能 / 細胞膜 / バリア機能 / 酵素 / 極長鎖脂肪酸 / スフィンゴ脂質 / セラミド / 脂質 Except Principal Investigator GPNMB / 白斑 … More / 細胞障害性 / ロドデンドロール / NRF2 / 酸化ストレス / 紫外線 / 皮膚がん / 発がん抑制 / 尋常性白斑 / 表皮細胞 / 発がん / 細胞接着 / 分化 / ケラチノサイト / 皮膚科学 / 化学白斑 / メラノーマ / ロドデノール / immunusupressant / mast cell / ceramide / C1P / Sphingosine 1-phosphate (S1P) / bioactive / biomolecule / sphingolipid / 血漿 / 生理活性脂質 / セミラド1-リン酸 / セミラド / スフィンゴ脂質 / 免疫抑制剤 / マスト細胞 / セラミド / セラミド1-リン酸 / スフィンゴシン1-リン酸 / 生理活性 / 生体分子 / 脂質 Less

ヒト表皮細胞の分化能保持におけるGPNMBの機能的役割の解明Principal Investigator
- Principal Investigator
  
  水谷有紀子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu Pharmaceutical University
Mechanism of low risk of carcinogenesis focused on reduced GPNMB expression in the basal layer of vitiligo epidermis
- Principal Investigator
  
  井上紳太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gifu Pharmaceutical University
Identification and analysis of molecules involved in the susceptibility of melanocytes to oxidative stress in vitiligo pathogenesis
- Principal Investigator
  
  Inoue Shintarou
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Gifu Pharmaceutical University
Establishment of a cytotoxicity evaluation system for pigment cell-specific vitiligo-inducing substances and elucidation of the mechanism of damage
- Principal Investigator
  
  Inoue Shintaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Gifu Pharmaceutical University
Very long chain ceramide biosynthesis and its molecular mechanismPrincipal Investigator
- Principal Investigator
  
  MIZUTANI Yukiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Nagoya University
  Hokkaido University
Biological functions of Sphingolipids and their relevance to pathological phenomena
- Principal Investigator
  
  YASUYUKI Igarashi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Hokkaido University

All 2021 2020 2013 2012 2011 2010 2007 2006 Other

All Journal Article Presentation Book

[Book] 「セラミド-基礎と応用- ここまできたセラミド研究最前線」2011
- Author(s)
  五十嵐靖之、水谷有紀子
- Publisher
  食品化学新聞社
- Data Source
  KAKENHI-PROJECT-22770095
[Book] セラミド　基礎と応用　ここまできたセラミド研究最前線2011
- Author(s)
  水谷有紀子
- Publisher
  食品化学新聞社
- Data Source
  KAKENHI-PROJECT-22770095
[Journal Article] Cooperaive Synthesis of Ultra Long-chain Fattyt Acid and Ceramide during Keratinocyte Differentiation2013
- Author(s)
  Yukiko Mizutani, Hui Sun, Yusuke Ohno, Takayuki Sassa, Takeshi Wakashima2, Mari Obara1, Kohei Yuyama1, Akio Kihara2*, Yasuyuki Igarashi1*
- Journal Title
  
  ProsOne
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770095
[Journal Article] Phytoceramide and sphingoid bases derived from brewer ' s yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors2011
- Author(s)
  Itsuo Murakami, Yukari Wakasa, Shinji Yamashita, Toshio Kurihara, Kota Zama, Naoyuki Kobayashi, Yukiko Mizutani, Susumu Mitsutake, Tatsuro Shigyo and Yasuyuki Igarashi
- Journal Title
  
  Lipids in Health and Disease
  
  Volume: 10 Issue: 1 Pages: 120-120
- DOI
  10.1186/1476-511x-10-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770095, KAKENHI-PROJECT-23780344
[Journal Article] ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis2010
- Author(s)
  Yusuke Ohno, Shota Suto, Masao Yamanaka, Yukiko Mizutani, Susumu Mitsutake, Yasuyuki Igarashi, Takayuki Sassa, and Akio Kihara
- Journal Title
  
  Proc. Natl. Acad. Sci
  
  Volume: 107 Issue: 43 Pages: 18439-44
- DOI
  10.1073/pnas.1005572107
- NAID
  120002934261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770095
[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007
- Author(s)
  Kihara A, Mitsutake S, Mizutani Y, Igarashi Y.
- Journal Title
  
  Prog. Lipid Res. Mar; 46(2)
  
  Pages: 126-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007
- Author(s)
  Kihara A, Mitsutake S, Mizutani Y, Igarashi Y.
- Journal Title
  
  Prog. Lipid Res. Mar;46(2)
  
  Pages: 126-44
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007
- Author(s)
  Kihara A, Mitsutake S, Mizutani Y, Igarashi Y.
- Journal Title
  
  Prog. Lipid Res 46(2)
  
  Pages: 126-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro) ceramide synthase with relatively broad substrate specificity2006
- Author(s)
  Mizutani, et al.
- Journal Title
  
  Biochemical Journal 398・3
  
  Pages: 531-538
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] LASS3 is a testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity.2006
- Author(s)
  Mizutani Y, KiharaA, Igarashi Y.
- Journal Title
  
  Biochem. J 398(3)
  
  Pages: 531-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18370050
[Journal Article] LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro) ceramide synthase with relatively broad substrate specificity2006
- Author(s)
  Mizutani , et. al.
- Journal Title
  
  Biochemical Journal 398・3
  
  Pages: 531-538
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18370050
[Presentation] GPNMBはNRF2非依存的にヒト表皮細胞の酸化ストレス抵抗性に寄与している2021
- Author(s)
  西田那月, 大津麻里子, 水谷有紀子, 井上紳太郎
- Organizer
  第3回日本白斑学会学術大会
- Data Source
  KAKENHI-PROJECT-20K08657
[Presentation] Compensatory action of anti-oxidative GPNMB in NRF2-deficient human melanoma clones to evaluate vitiligo-risk compounds.2020
- Author(s)
  Nishida N.,Ishitsuka A, Mizutani A, Nakayama H, Higashiyama H, Inoue S.
- Organizer
  The 24th International Pigment Cell Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10248
[Presentation] Cooperative Synthesis of Ultra Long-chain Fatty Acid and Ceramide during Keratinocyte Differentiation2013
- Author(s)
  Yukiko Mizutani, Hui Sun, Yusuke Ohno, Takeshi Wakashima, Mari Obara, Kohei Yuyama, Toyoshi Fujimoto, Akio Kharai, Yasuyuki Igarashi
- Organizer
  第5回グローバルリトリート
- Place of Presentation
  大府
- Year and Date
  2013-02-01
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] セラミド単行本発刊記念セミナー「セラミドの機能について～セラミドは食べて効く2012
- Author(s)
  水谷有紀子、五十嵐靖之
- Organizer
  ifia JAPAN 2012
- Place of Presentation
  東京
- Year and Date
  2012-05-24
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] 皮膚におけるフィトセラミドの生成機構について2011
- Author(s)
  水谷有紀子、東城博雅、村上逸雄、木原章雄、五十嵐靖之
- Organizer
  第4回セラミド研究会
- Place of Presentation
  札幌
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] 皮膚初代培養細胞における極長鎖脂肪酸伸長酵素の発現について2010
- Author(s)
  水谷有紀子
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] Ceramide biosynthesis in keratinocyte and its regulation by PPAR activators2010
- Author(s)
  Yukiko Mizutani, Akio Kihara, Yasuyuki Igarashi
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] Ceramide biosynthesis in keratinocyte and its regulation by PPAR activators2010
- Author(s)
  Yukiko Mizutani, Akio Kihara, Yasuyuki Igarashi
- Organizer
  第27回内藤カンファレンス
- Place of Presentation
  札幌
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] 皮膚におけるフィトセラミドの生成機構について
- Author(s)
  水谷有紀子
- Organizer
  第4回セラミド研究会
- Place of Presentation
  北海道大学学術交流会館（札幌）
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] Cooperative Synthesis of Ultra Long-chain Fatty Acid and Ceramide during Keratinocyte Differentiation
- Author(s)
  水谷有紀子
- Organizer
  第5回グローバルリトリート
- Place of Presentation
  愛知健康プラザ（大府）
- Data Source
  KAKENHI-PROJECT-22770095
[Presentation] セラミドの機能について　セラミドは食べて効く？
- Author(s)
  水谷有紀子
- Organizer
  ifia JAPAN 2012
- Place of Presentation
  東京ビックサイト（東京）
- Invited
- Data Source
  KAKENHI-PROJECT-22770095

1. Inoue Shintaro (00793853)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. YASUYUKI Igarashi (70091965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. KIHARA Akio (50333620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. MITSUTAKE Susumu (10344475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. IWAKI Soichiro (60399962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石塚麻子 (50727203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Yukiko Mizutani 水谷 有紀子

水谷 有紀子 ミズタニ ユキコ

MIZUTANI Yukiko 水谷 有紀子

Research Projects

Research Products

Co-Researchers

ヒト表皮細胞の分化能保持におけるGPNMBの機能的役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of low risk of carcinogenesis focused on reduced GPNMB expression in the basal layer of vitiligo epidermis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and analysis of molecules involved in the susceptibility of melanocytes to oxidative stress in vitiligo pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a cytotoxicity evaluation system for pigment cell-specific vitiligo-inducing substances and elucidation of the mechanism of damage

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Very long chain ceramide biosynthesis and its molecular mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological functions of Sphingolipids and their relevance to pathological phenomena

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 「セラミド-基礎と応用- ここまできたセラミド研究最前線」2011

Author(s)

Publisher

Data Source

[Book] セラミド 基礎と応用 ここまできたセラミド研究最前線2011

Author(s)

Publisher

Data Source

[Journal Article] Cooperaive Synthesis of Ultra Long-chain Fattyt Acid and Ceramide during Keratinocyte Differentiation2013

Author(s)

Journal Title

Data Source

[Journal Article] Phytoceramide and sphingoid bases derived from brewer ' s yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis2010

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007

Author(s)

Journal Title

Data Source

[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Metabolism and biological functions of two phosphorylated sphingolipids, sphingosine 1-phosphate and ceramide 1-phosphate.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro) ceramide synthase with relatively broad substrate specificity2006

Yukiko Mizutani 水谷有紀子

水谷有紀子ミズタニユキコ

MIZUTANI Yukiko 水谷有紀子

[Book] セラミド　基礎と応用　ここまできたセラミド研究最前線2011

[Presentation] セラミドの機能について　セラミドは食べて効く？