Hashimoto Koshi 橋本貢士

… Alternative Names

HASHIMOTO Kohshi 橋本貢士

橋本真士ハシモトコウシ

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Researcher Number	30396642
Other IDs	https://orcid.org/0000-0002-3530-689X
Affiliation (Current)	2024: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 獨協医科大学, 医学部, 教授 2016 – 2018: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座准教授 2013 – 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2013: 東京医科歯科大学, 医歯(薬)学総合研究科, 寄附講座准教授 2011 – 2012: 群馬大学, 医学(系)研究科(研究院), 助教 2007 – 2012: 群馬大学, 大学院・医学系研究科, 助教 2009: 群馬大学, 大学院・医学系研究科, 講師
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / Endocrinology Except Principal Investigator Basic Section 59020:Sports sciences-related / Applied health science / Endocrinology / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator エピジェネティクス / エピゲノム記憶 / CREB / 遺伝子 / 摂食抑制 / Nesfatin-1 / バイオマーカー / 自己免疫性多発性内分泌腺症候群3型 / バセドウ病 / Graves' disease … More / Siglec1 / DOHaD学説 / Hepa1-6 / TET / HTVi / PPARαノックアウトマウス / TET1 / CRISPR-dCas9 / DNA脱メチル化 / エピゲノム編集 / エピゲノム制御 / PPARα / FGF21 / 遺伝子特異的DNA脱メチル化 / CRISPR-dCas9-TET1CD系 / 高次脳機能 / 甲状腺機能低下症 / 中枢神経系 / 行動試験 / 母体甲状腺機能低下症 / 妊娠 / 甲状腺ホルモン / DOHaD / DNAメチル化 / 水迷路試験 / 学習・認知能力低下 / 海馬 / BDNF / 妊娠期 / 甲状腺機能低下 / リン酸化CRE 結合蛋白(p-CREB) / 細胞内シグナル伝達機構 / [35S]GTPγS アッセイ / Nap-1受容体 / Nap-1 / M30 / 視床下部 / 膵β細胞 / 細胞内シグナル伝達 / 摂食抑制ペプチド / Nesfatin-1受容体 / DNAマイクロアレイ / G蛋白共役型受容体 / MC4R / シグナル伝達 / 受容体 / メタボリックシンドローム … More Except Principal Investigator エピジェネティクス / 糖尿病 / DNAメチル化 / 糖尿病性腎症 / QOL / 運動療法 / DOHaD / 肥満 / Nesfatin-1 / 視床下部 / 受容体 / 糖尿病運動療法 / 高齢者 / 甲状腺機能異常合併妊娠 / 臍帯血 / 母児の甲状腺機能 / 新生児の甲状腺機能 / 妊娠期の甲状腺機能 / 潜在性甲状腺機能低下症合併妊娠 / 妊婦の抗甲状腺抗体 / 出生児体重 / 甲状腺機能 / 妊娠 / 出生時体重 / 分娩 / 妊婦 / 潜在性甲状腺機能低下症 / 母子の甲状腺機能 / 先制医療 / DOHaD仮説 / エピゲノム制御 / エピゲノム記憶 / DNA脱メチル化 / エピジェネティックメモリー / FGF21 / PPARα / 飽和脂肪酸 / n-3系脂肪酸 / 生活習慣病 / PPAR / エピゲノム / 魚油 / 脂肪酸 / サイクリックAMP / ジーンターゲティング / G蛋白共役型受容体 / 膵β細胞 / リン酸化CRE結合蛋白(p-CREB) / メラノコルチン受容体 / 遺伝子 / アピトサイトカイン / ネスファチン-1 / 脂肪細胞 / 摂食抑制 / シグナル伝達 / Body weight / Receptor / Appetite / Hypothalamus / Obesity / ノックアウトマウス / 食欲調節 / Nesfatin Less

Elucidation of clinicopathological significance of Siglec1 in Graves' disease and clinical application of Siglec1Principal Investigator
- Principal Investigator
  
  橋本貢士
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Dokkyo Medical University
「自宅で一人でできる」運動療法の患者QOL改善と糖尿病性腎症重症化抑制効果の検証
- Principal Investigator
  
  原健二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Dokkyo Medical University
Exercise therapy against the development of diabetic kidney disease
- Principal Investigator
  
  Hara Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Dokkyo Medical University
Elucidation of molecular mechanism of epigenetic memory of FGF21 gene and its functional significance in vivo.Principal Investigator
- Principal Investigator
  
  Hashimoto Koshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Dokkyo Medical University
reration of subclinical hypothyroidism and fetal and maternal complications
- Principal Investigator
  
  Wada Michiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Elucidation of epigenetic control by fatty acid against metabolic syndrome
- Principal Investigator
  
  TAKAHASHI MAYUMI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Osaka Women's Junior College
Epigenetic analysis of gene expression in central nervous system of offspring derived from dam with hypothyroxinemia during pregnancyPrincipal Investigator
- Principal Investigator
  
  Hashimoto Koshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Tokyo Medical and Dental University
Analysis of epigenetic memory of FGF21 gene in the liver
- Principal Investigator
  
  Yuan Xunmei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanism of intracellular and in vivo function of an anorexic peptide, Nesfatin-1Principal Investigator
- Principal Investigator
  
  HASHIMOTO Koshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Tokyo Medical and Dental University
  Gunma University
Studies on signal activating systems induced by an anorexigenicappetitekine, Nesfatin-1
- Principal Investigator
  
  MORI Masatomo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Endocrinology
- Research Institution
  Gunma University
Analysis of intracellular signaling pathway of an anorexic hormone 'Nesfatin-1'.Principal Investigator
- Principal Investigator
  
  HASHIMOTO Koshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Gunma University
Identification of a receptor for an anorexigenic molecule, Nesfatin-1, and its signal transduction systems
- Principal Investigator
  
  MOR Masatomo
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Endocrinology
- Research Institution
  Gunma University

[Book] 甲状腺専門医ガイドブック2016
- Author(s)
  橋本貢士ら、日本甲状腺学会編
- Total Pages
  341
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] Analysis of time-dependent changes in the FIB4 index in patients with obesity receiving weight reduction therapy2022
- Author(s)
  Kawai Shiori、Yamakage Hajime、Kotani Kazuhiko、Noda Mitsuhiko、Satoh-Asahara Noriko、Hashimoto Koshi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 15219-15219
- DOI
  10.1038/s41598-022-19420-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11720, KAKENHI-PROJECT-22K19723, KAKENHI-PROJECT-21H02835, KAKENHI-PROJECT-19K07905, KAKENHI-PROJECT-20K11394
[Journal Article] Seasonal variations and the influence of COVID-19 pandemic on hemoglobin A1c, glycoalbumin, and low-density lipoprotein cholesterol2022
- Author(s)
  Takebayashi Kohzo、Yamauchi Mototaka、Hara Kenji、Tsuchiya Takafumi、Hashimoto Koshi
- Journal Title
  
  Diabetology International
  
  Volume: 8 Issue: 4 Pages: 1-7
- DOI
  10.1007/s13340-022-00574-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-20K11394
[Journal Article] DOHaD学説における肥満症の個人差と精密医療への展望2021
- Author(s)
  橋本　貢士
- Journal Title
  
  実験医学
  
  Volume: 39 Pages: 767-774
- Data Source
  KAKENHI-PROJECT-19K09018
[Journal Article] Serum thyroid-stimulating hormone receptor antibody levels and thyroid dysfunction after hysterosalpingography: a case-control study2021
- Author(s)
  So Shuhei、Hashimoto Koshi、Mori Masatomo、Endo Shigeki、Yamaguchi Wakasa、Miyano Naomi、Murabayashi Nao、Tawara Fumiko
- Journal Title
  
  Gynecological Endocrinology
  
  Volume: 37 Issue: 10 Pages: 898-901
- DOI
  10.1080/09513590.2021.1963430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09018
[Journal Article] 2型糖尿病および肥満におけるDNAメチル化の最新知見2021
- Author(s)
  橋本　貢士
- Journal Title
  
  医学のあゆみ
  
  Volume: 276 Pages: 453-457
- Data Source
  KAKENHI-PROJECT-19K09018
[Journal Article] 周産期栄養とエピジェネティクス2021
- Author(s)
  橋本　貢士
- Journal Title
  
  小児内科
  
  Volume: 53 Pages: 1818-1824
- Data Source
  KAKENHI-PROJECT-19K09018
[Journal Article] Association of circulating soluble lectin-like oxidized low-density lipoprotein receptor-1 with inflammatory markers and urinary albumin excretion in patients with type 2 diabetes2021
- Author(s)
  Takebayashi Kohzo、Suzuki Tatsuhiko、Yamauchi Mototaka、Hara Kenji、Tsuchiya Takafumi、Inukai Toshihiko、Hashimoto Koshi
- Journal Title
  
  SAGE Open Medicine
  
  Volume: 9 Pages: 1-7
- DOI
  10.1177/20503121211064468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-20K11394
[Journal Article] Severe Non-Islet Cell Hypoglycemia From Ileum-Origin Gastrointestinal Stromal Tumor Producing Insulin-Like Growth Factor-2 in a Patient With Liver Cirrhosis Due to Chronic Hepatitis B2020
- Author(s)
  Takebayashi Kohzo、Furukawa Sho、Okumura Takenori、Kubo Mio、Ujiie Atsushi、Yamauchi Mototaka、Shinozaki Hiroyuki、Hara Kenji、Tsuchiya Takafumi、Ono Yuko、Inukai Toshihiko、Hashimoto Koshi
- Journal Title
  
  Journal of Clinical Medicine Research
  
  Volume: 12 Issue: 12 Pages: 824-830
- DOI
  10.14740/jocmr4326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11394
[Journal Article] Hb Phnom Penh Showing Falsely High or Reasonable HbA1c Values Depending on the Type of High-performance Liquid Chromatography System2020
- Author(s)
  Hara Kenji、Koga Masafumi、Shinozaki Hiroyuki、Yamauchi Mototaka、Suzuki Tatsuhiko、Naruse Rika、Tsuchiya Takafumi、Takebayashi Kohzo、Inukai Toshihiko、Hashimoto Koshi
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 6 Pages: 805-809
- DOI
  10.2169/internalmedicine.3306-19
- NAID
  130007808727
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-03-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K11394
[Journal Article] Ascorbic acid during the suckling period is required for proper DNA demethylation in the liver2020
- Author(s)
  Kawahori Kenichi、Kondo Yoshitaka、Yuan Xunmei、Kawasaki Yuki、Hanzawa Nozomi、Tsujimoto Kazutaka、Wada Fumiko、Kohda Takashi、Ishigami Akihito、Yamada Tetsuya、Ogawa Yoshihiro、Hashimoto Koshi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 21228-21228
- DOI
  10.1038/s41598-020-77962-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-19H04043
[Journal Article] Targeted DNA demethylation of the Fgf21 promoter by CRISPR/dCas9-mediated epigenome editing.2020
- Author(s)
  Hanzawa N, Hashimoto K, Yuan X, Kawahori K, Tsujimoto K, Hamaguchi M, Tanaka T, Nagaoka Y, Nishina H, Morita S, Hatada I, Yamada T, Ogawa Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 10 Issue: 1 Pages: 5181-5181
- DOI
  10.1038/s41598-020-62035-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06607, KAKENHI-PROJECT-19K18000, KAKENHI-PROJECT-17H03613, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K01840, KAKENHI-PROJECT-19K09018, KAKENHI-PROJECT-20H03381
[Journal Article] A Possible Beneficial Effect of Sex Hormones on Vascular Aging through Expression of Sirtuin 1 Gene ：A Narrative Review of the Literature.2020
- Author(s)
  Tsuchiya T, Inukai T, Hara K, Takebayashi K, Hashimoto K.
- Journal Title
  
  Gene Technol
  
  Volume: 9 Pages: 100050-100050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11394
[Journal Article] TSH測定に関する問題点と潜在性甲状腺機能低下症2017
- Author(s)
  橋本貢士
- Journal Title
  
  医学のあゆみ
  
  Volume: 260 Pages: 735-740
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] エネルギー代謝とDNAメチル化制御2016
- Author(s)
  辻本和峰, 橋本貢士, 袁勲梅, 川堀健一, 榛澤望, 小川佳宏
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 2493-2499
- Data Source
  KAKENHI-PROJECT-26350884
[Journal Article] 【糖尿病と妊娠-児と母体の最新知識-】児からみた妊娠と糖尿病　乳幼児の栄養と児の将来の生活習慣病2016
- Author(s)
  橋本貢士、小川佳宏
- Journal Title
  
  プラクティス
  
  Volume: 33 Pages: 172-177
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] 【最近の日本人の肥満症-新知見が拓くこれからの肥満症診療】肥満症のメカニズム　エピゲノムと肥満症2016
- Author(s)
  橋本貢士、小川佳宏
- Journal Title
  
  カレントテラピー
  
  Volume: 34 Pages: 39-44
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] エネルギー代謝とエピジェネティクス2016
- Author(s)
  橋本貢士、小川佳宏
- Journal Title
  
  Diabetes Frontier
  
  Volume: 27 Pages: 19-28
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] Serum free thyroxine levels are associated with the efficacy of weight reduction therapy in obese female patients2016
- Author(s)
  Hashimoto K, Tagami T, Yamakage H, Muranaka K, Tanaka M, Odori S, Kono S, Shimatsu A, Ogawa Y, Satoh-Asahara N.
- Journal Title
  
  Endocr J
  
  Volume: 63 Issue: 3 Pages: 221-229
- DOI
  10.1507/endocrj.EJ15-0498
- NAID
  130005140783
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461376, KAKENHI-PROJECT-15K08634
[Journal Article] 肥満がもたらす病態生理の発症メカニズム　肥満とDOHaD仮説2016
- Author(s)
  橋本貢士、小川佳宏
- Journal Title
  
  実験医学
  
  Volume: 34 Pages: 331-336
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] Type 2 Amiodarone-Induced Thyrotoxicosis That Underwent Total Thyroidectomy under High-Dose Steroid Administration.2015
- Author(s)
  Hashimoto K, Ota M, Irie T, Takata D, Nakajima T, Kaneko Y, Tanaka Y, Matsumoto S, Nakajima Y, Kurabayashi M, Oyama T, Takeyoshi I, Mori M, Yamada M.
- Journal Title
  
  Case Rep Endocrinol
  
  Volume: 2015 Pages: 416145-416145
- DOI
  10.1155/2015/416145
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] 糖尿病をはじめとする代謝疾患とエピゲノム2015
- Author(s)
  高椅真由美、橋本貢士、小川佳宏
- Journal Title
  
  医学のあゆみ
  
  Volume: 255 Pages: 683-689
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] DOHaDの動物モデル2015
- Author(s)
  辻本和峰、橋本貢士、小川佳宏
- Journal Title
  
  HORMONE FRONTIER IN GYNECOLOGY
  
  Volume: 22 Pages: 281-286
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] DOHaD仮説とエピゲノム医療の可能性2014
- Author(s)
  橋本貢士、小川佳宏
- Journal Title
  
  医学のあゆみ
  
  Volume: 250 Pages: 859-862
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] 甲状腺ホルモンによる遺伝子制御機構Update2014
- Author(s)
  橋本貢士
- Journal Title
  
  ホルモンと臨床
  
  Volume: 61 Pages: 81-86
- Data Source
  KAKENHI-PROJECT-26461376
[Journal Article] Ligand-activated PPARα-dependent DNA demethylation regulates the fatty acid β-oxidation genes in the postnatal liver.2014
- Author(s)
  Ehara T, Kamei Y, Yuan X, Takahashi M, Kanai S, Tamura E, Tsujimoto K, Tamiya T, Nakagawa Y, Shimano H, Takai-Igarashi T, Hatada I, Suganami T, Hashimoto K, Ogawa Y.
- Journal Title
  
  Diabetes.
  
  Volume: 64(3) Issue: 3 Pages: 775-84
- DOI
  10.2337/db14-0158
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390230, KAKENHI-PUBLICLY-25126701, KAKENHI-PUBLICLY-25126723, KAKENHI-PROJECT-26670448, KAKENHI-PROJECT-26350884, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-25292076
[Journal Article] Discovery of nesfatin-1 and overview of biological actions and new developments2013
- Author(s)
  Mori M, Yamada M, Okada S, Hashimoto K, Satoh T, Shimizu H, Yada T
- Journal Title
  
  Curr Pharm Des
  
  Volume: 19 Pages: 6921-6928
- URL
  http://www.eurekaselect.com/118383/article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591296
[Journal Article] Secreted Nucleobindin-2 inhibits 3T3-L1 adipocyte differentiation2012
- Author(s)
  Tagaya Y, Osaki A, Miura A, Okada S, Ohshima K, Hashimoto K, Yamada M, Satoh T, Shimizu H, Mori M
- Journal Title
  
  Protein Pept. Lett
  
  Volume: 19 Pages: 997-1004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038
[Journal Article] Nesfatin-1 Induces the Phosphorylation Levels of cAMP Response Element-Binding Protein for Intracellular Signaling in a Neural Cell Line2012
- Author(s)
  Ishida E, Hashimoto K, Shimizu H, Okada S, Satoh T, Kato I, Yamada M, Mori M
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038
[Journal Article] Secreted nucleobindin-2 inhibits 3T3-L1 adipocyte differentiation2012
- Author(s)
  Tagaya Y, Osaki A, Miura A, Okada S, Ohshima K, Hashimoto K, Yamada M, Satoh T, Shimizu H, Mori M
- Journal Title
  
  Protein Pept Lett
  
  Volume: 19 Pages: 997-1004
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468916/pdf/PPL-19-997.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591296
[Journal Article] Nesfatin-1 Induces the Phosphorylation Levels of cAMP Response Element-Binding Protein for Intracellular Signaling in a Neural Cell Line.2012
- Author(s)
  Ishida E
- Journal Title
  
  PLoS One
  
  Volume: 7(12) Issue: 12 Pages: e50918-e50918
- DOI
  10.1371/journal.pone.0050918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038, KAKENHI-PROJECT-23591296, KAKENHI-PROJECT-23591332, KAKENHI-PLANNED-22126010
[Journal Article] Nesfatin-1 Induces the Phosphorylation Levels of cAMP Response Element-Binding Protein for Intracellular Signaling in a Neural Cell Line.2012
- Author(s)
  Ishida E, Hashimoto K, Shimizu H, Okada S, Satoh T, Kato I, Yamada M, Mori M
- Journal Title
  
  PLoS One
  
  Volume: 7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591296
[Journal Article] Troglitazone, a ligand of peroxisome proliferator-activated receptor-γ, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway : isolation and characterization of the human NUCB2 gene.2010
- Author(s)
  Yamada M, Horiguchi K, Umezawa R, Hashimoto K, Satoh T, Ozawa A, Shibusawa N, Monden T, Okada S, Shimizu H, Mori M.
- Journal Title
  
  Endocrinology.
  
  Volume: 151 Pages: 2494-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038
[Journal Article] Troglitazone, a ligand of peroxisome proliferator-activatedreceptor-g, stabilizes NUCB2 (Nesfatin)mRNA by activating the ERK1/2 pathway:isolation and characterization of the human NUCB2 gene2010
- Author(s)
  Yamada M, Horiguchi K, Umezawa R, Hashimoto K, Satoh T, Ozawa A,Shibusawa N, Monden T, Okada S, Shimizu H, Mori M
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 2494-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038
[Journal Article] Troglitazone, a ligand of peroxisome proliferator-activated receptor-γ, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway : isolation and characterization of the human NUCB2 gene.2010
- Author(s)
  Yamada M, Horiguchi K, Urnezawa R, Hashimoto K, Satoh T, Ozawa A, Shibusawa N, Monden T, Okada S, Shimizu H, Mori M.
- Journal Title
  
  Endocrinology.
  
  Volume: 151 Pages: 2494-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males.2010
- Author(s)
  Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh-I S, Ariyama Y, Takahashi H, Okada S, Hashimoto K, Satoh T, Kojima M, Mori M
- Journal Title
  
  Clin Endocrinol (Oxf). 73
  
  Pages: 484-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males.2010
- Author(s)
  Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh-I S, Ariyama Y, Takahashi H, Okada S, Hashimoto K, Satoh T, Kojima M, Mori M.
- Journal Title
  
  Clin Endocrinol (Oxf).
  
  Volume: 73 Pages: 484-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Fasting concentrations of nesfatin-1 are negatively correlated with body mass index in non-obese males.2010
- Author(s)
  Tsuchiya T, Shimizu H, Yamada M, Osaki A, Oh-I S, Ariyama Y, Takahashi H, Okada S, Hashimoto K, Satoh T, Kojima M, Mori M.
- Journal Title
  
  Clin Endocrinol.
  
  Volume: 73 Pages: 484-490
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249038
[Journal Article] Troglitazone, a ligand of peroxisome proliferator-activated receptor-{gamma}, stabilizes NUCB2 (Nesfatin) mRNA by activating the ERK1/2 pathway : isolation and characterization of the human NUCB2 gene.2010
- Author(s)
  Yamada M, Horiguchi K, Umezawa R, Hashimoto K, Satoh T, Ozawa A, Shibusawa N, Monden T, Okada S, Shimizu H, Mori M
- Journal Title
  
  Endocrinology. 151
  
  Pages: 2494-2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone2009
- Author(s)
  Hashimoto K, Ishida E, Matsumoto S, Okada S, Yamada M, Satohj T, Monden T, Mori M.
- Journal Title
  
  Endocrinology 150
  
  Pages: 3417-3424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Peripheral administration of nesfatin-1 reduces food intake in mice : the leptin-independent mechanism.2009
- Author(s)
  Shimizu H, Oh-I S, Hashimoto K, Nakata M, Yamamoto S, Yoshida N, Eguchi H, Kato I, Inoue K, Satoh T, Okada S, Yamada M, Yada T, Mori M
- Journal Title
  
  Endocrinology. 150
  
  Pages: 662-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Liver X receptor-alpha positively regulates proopiomelanocortin (POMC) gene expression at the transcriptional level in the pituitary2009
- Author(s)
  Matsumoto S, Hashimoto K, Yamamda M, Satoh T, Hirato J, Mori M.
- Journal Title
  
  Mol Endocrinol 23
  
  Pages: 47-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.2009
- Author(s)
  Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T
- Journal Title
  
  Cell Metab. 10
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Transcriptional activation of the MLL-p27kip1 pathway by a somatostatin analogue2009
- Author(s)
  Horiguchi K, Yamada M, Satoh T, Hashimoto K, Hirato J, Tosaka M, Yamada S, Mori M.
- Journal Title
  
  Clinical Cancer Res 15
  
  Pages: 2620-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Peripheral administration of nesfatin-1 reduces food intake in mice : the leptin-independent mechanism.2009
- Author(s)
  Shimizu H, Oh-IS, Hashimoto K, Nakata M, Yamamoto S, Yoshida N, Eguchi H, Kato I, Inoue K, Satoh T, Okada S, Yamada M, Yada T, Mori M.
- Journal Title
  
  Endocrinology 150
  
  Pages: 662-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Carbohydrate response element binding protein gene expression is positively regulated by thyroid hormone.2009
- Author(s)
  Hashimoto K, etal
- Journal Title
  
  Endocrinology 150
  
  Pages: 3417-3424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Nesfatin-1-regulated oxytocinergic signaling in the paraventricular nucleus causes anorexia through a leptin-independent melanocortin pathway.2009
- Author(s)
  Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-IS, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T.
- Journal Title
  
  Cell Metab. 10
  
  Pages: 355-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591045
[Journal Article] Peripheral administration of nesfatin-1 reduces food intake in mice : The leptin-independent mechanism2009
- Author(s)
  Shimizu H, Oh-I S, Hashimoto K, Nakata M, Yamamoto S, Yoshida N, Eguchi H, Kato I, Inoue K, Satoh T, Okada S, Yamada M, Yada T, Mori M.
- Journal Title
  
  Endocrinology 150
  
  Pages: 662-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Nesfatin-1-regulated paraventricular oxytocinergic signaling causes anorexia through a leptin-independent melanocortin pathway2009
- Author(s)
  Maejima Y, Sedbazar U, Suyama S, Kohno D, Onaka T, Takano E, Yoshida N, Koike M, Uchiyama Y, Fujiwara K, Yashiro T, Horvath TL, Dietrich MO, Tanaka S, Dezaki K, Oh-I S, Hashimoto K, Shimizu H, Nakata M, Mori M, Yada T.
- Journal Title
  
  Cell Metabolism 10
  
  Pages: 355-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Tat-bidning protein-1 (TBP-1), an ATPase of 19s regulatory particles of the 26s proteasome, enhances androgen receptor function in cooperation with TBP-1-interacting protein/Hop22009
- Author(s)
  Satoh T, Ishizuka T, Tomaru T, Yoshino S, Nakajima Y, Hashimoto K, Shibusawa N, Monden T, Yamada M, Mori M.
- Journal Title
  
  Endocrinology 150
  
  Pages: 3283-3290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] CDK5-dependent phosphorylation of the Rho family GTPase TC10 alpha regulates insulin-stimulated GLUT4 translocation2008
- Author(s)
  Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Uehara Y, Tsuchiya T, Shimizu H, Tatei K, Isumi Y, Yamauchi K, Hisanaga SI, Pessin JE, Mori M.
- Journal Title
  
  J Biol Chem 283
  
  Pages: 35455-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Tyrosine phosphorylation of munc 18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L-1 adipocytes2008
- Author(s)
  Umahara M, Okada S, Yamada E, Saito T, Ohshima K, Hashimoto K, Yamada M, Shimizu H, Pessin JF, Mori M.
- Journal Title
  
  Endocrinology 149
  
  Pages: 40-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] The satiety molecule nesfatin-1 is co-expressed with melanin concentrating hormone in tuberal hypothalamic neurons of the rat2008
- Author(s)
  Fort P, Salvert D, Hanriot L, Jego S, Shimizu H, Hashimoto K, Mori M, Luppi PH.
- Journal Title
  
  Neuroscience 155
  
  Pages: 174-181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Liver X receptor-αgene expressio is positively regulated by thyroid horm one.2007
- Author(s)
  Hashimoto K, et. al.
- Journal Title
  
  Endocrinology 148
  
  Pages: 4667-4675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Synip phosphorylation is reguired for insulin-stimulated glut 4 translocation2007
- Author(s)
  Okada S, Ohsima K, Uehara Y, Shimizu H, Hashimoto K, Yamada M, Mori M.
- Journal Title
  
  Biochem Biophy Res Commun 356
  
  Pages: 102-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Journal Article] Liver X receptor-αgene expression is positively regulated by thyroid hormone2007
- Author(s)
  Hashimoto K, Mathsmoto S, Yamada M, Satoh T, Mori M.
- Journal Title
  
  Endocrinology 148
  
  Pages: 4667-4675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209035
[Presentation] コロナ禍における肥満2型糖尿病患者を対象とした新規在宅運動療法プログラムの構築とその実践2022
- Author(s)
  原　健二, 氏家　淳 , 奥村武憲 , 浅井久美子 , 滝井寛隆, 原かほり, 宮川きらら, 鈴木　栞, 久保未央, 古川　翔 , 山内元貴, 土屋天文, 竹林晃三, 橋本貢士
- Organizer
  第42回日本肥満学会学術集会
- Data Source
  KAKENHI-PROJECT-20K11394
[Presentation] エピゲノム改変動物を用いたFibroblast growth factor 21(FGF21)遺伝子DNAメチル化の機能的意義解明2021
- Author(s)
  辻本和峰, 橋本貢士, 榛澤望, 川堀健一, 袁勲梅, 長岡勇也, 仁科博史, 畑田出穂, 山田哲也, 小川佳宏
- Organizer
  第64回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K09018
[Presentation] Developmental Origins of Health and Disease （DOHaD）学説の見地に立った肝臓でのDNA脱メチル化におけるビタミンCの重要性2021
- Author(s)
  橋本貢士
- Organizer
  日本ビタミン学会第73回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09018
[Presentation] DOHaD 学説とエピゲノム記憶2020
- Author(s)
  橋本貢士
- Organizer
  第42回日本臨床栄養学会総会・第41回日本臨床栄養協会総会　第18回大連合大会　シンポジウム　「栄養シグナルと食物アレルギー」
- Invited
- Data Source
  KAKENHI-PROJECT-19K09018
[Presentation] Epigenetics in early life, which affects obesity in later life2020
- Author(s)
  Koshi Hashimoto
- Organizer
  The International Association of the Diabetes and Pregnancy Study Groups 2020 meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09018
[Presentation] CRISPR/dCas9 系による Fibroblast growth factor 21 遺伝子特異的 DNA 脱メチル化の導入2019
- Author(s)
  橋本貢士
- Organizer
  日本ゲノム編集学会　第４回大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09018
[Presentation] 母獣が摂取する飽和脂肪酸およびn-3系脂肪酸油脂による仔の肝臓でのDNAメチル化への影響2017
- Author(s)
  高橋真由美、袁勲梅、山崎聖美、橋本貢士、小川佳宏
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-15K01740
[Presentation] 母獣の食餌性脂肪酸による仔の肝臓における遺伝子発現とDNAメチル化の検討2017
- Author(s)
  高橋真由美、袁勲梅、山崎聖美、橋本貢士、小川佳宏
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-15K01740
[Presentation] 母獣の食餌性脂肪酸による仔の肝臓における遺伝子発現制御の検討2016
- Author(s)
  高橋真由美、袁勲梅、山崎聖美、橋本貢士、小川佳宏
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K01740
[Presentation] DNA Methylation Status in Early Life as an Epigenetic Memory and Its Physiological Significance in Later Life.2016
- Author(s)
  Hashimoto K, Ogawa Y
- Organizer
  NEW ZEALAND-JAPAN JOINT DOHaD SEMINAR supported by The Japan Society for the Promotion of Science (JSPS)
- Place of Presentation
  オークランド大学リギンス研究所（ニュージーランド、オークランド）
- Year and Date
  2016-02-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 母獣が摂取する飽和脂肪酸およびn-3系不飽和脂肪酸油脂が及ぼす仔の肝臓における遺伝子発現への影響2016
- Author(s)
  高橋真由美、袁勲梅、橋本貢士、小川佳宏
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  兵庫
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K01740
[Presentation] 新規バイオマーカーSiglec1によるバセドウ病の再燃、再発予測2016
- Author(s)
  橋本貢士
- Organizer
  第29回　甲状腺眼症研究会
- Place of Presentation
  ステーションコンファレンス東京（東京都、千代田区）
- Year and Date
  2016-03-19
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 胎仔期から乳仔期における母体栄養環境に応じた代謝関連遺伝子発現のDNAメチル化制御2016
- Author(s)
  袁勲梅, 橋本貢士, 辻本和峰, 川堀健一, 榛澤望, 中林一彦, 秦健一郎, 伊東宏晃, 小川佳宏
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウンビル（東京）
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] 母獣が摂取する飽和脂肪酸およびn-3系脂肪酸油脂が及ぼす仔の肝臓における遺伝子発現への影響2016
- Author(s)
  高橋真由美、袁勲梅、橋本貢士、小川佳宏
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  神戸。西宮
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K01740
[Presentation] 母獣が摂取する飽和脂肪酸およびn-3系脂肪酸油脂が及ぼす仔の肝臓における遺伝子発現への影響2016
- Author(s)
  高橋真由美、袁勲梅、橋本貢士、小川佳宏
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  神戸ポートピアホテル（神戸）
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] Fibroblast growth factor 21遺伝子発現のエピゲノム制御と機能的意義2016
- Author(s)
  辻本和峰, 橋本貢士, 袁勲梅, 川堀健一, 榛澤望, 小川佳宏
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウンビル（東京）
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] Fibroblast growth factor 21遺伝子のDNAメチル化制御機構とその生理的意義2016
- Author(s)
  橋本貢士, 袁勲梅, 辻本和峰, 川堀健一, 榛澤望, 小川佳宏
- Organizer
  第34回内分泌代謝サマーセミナー
- Place of Presentation
  久山温泉　ホテル夢家（福岡）
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] 妊娠期甲状腺機能低下マウスにおける仔の行動異常とその分子機構の解明2016
- Author(s)
  川堀健一, 橋本貢士, 加瀬早織, 辻本和峰, 袁勲梅, 藤田慶大, 田川一彦, 岡澤均, 小川佳宏
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 軽度甲状腺機能低下母獣マウスの産仔における学習・認知機能とBrain-derived neurotrophin factor (BDNF)遺伝子のDNAメチル化制御の解析2016
- Author(s)
  川堀健一, 橋本貢士, 袁勲梅, 辻本和峰, 加瀬早織, 藤田慶大, 田川一彦, 岡澤均, 小川佳宏
- Organizer
  第59回日本甲状腺学会学術集会
- Place of Presentation
  虎ノ門ヒルズフォーラム（東京）
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 妊娠期甲状腺機能低下マウスにおける産仔の行動異常のDNAメチル化制御2016
- Author(s)
  川堀健一, 橋本貢士, 袁勲梅, 辻本和峰, 加瀬早織, 藤田慶大, 田川一彦, 岡澤均, 小川佳宏
- Organizer
  第53回日本臨床分子医学会学術総会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] DOHaD仮説に基づく肝糖脂質代謝のエピゲノム制御2015
- Author(s)
  橋本貢士、小川佳宏
- Organizer
  日本内分泌学会第33回内分泌代謝学サマーセミナー
- Place of Presentation
  御花（福岡県、柳川市）
- Year and Date
  2015-07-09
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 胎仔期から乳仔期におけるマウスFibroblast Growth Factor 21(FGF21)遺伝子発現のエピゲノム制御2015
- Author(s)
  橋本貢士, 袁勲梅, 辻本和峰, 川堀健一, 小川佳宏
- Organizer
  第4回日本DOHaD研究会学術集会
- Place of Presentation
  昭和大学（東京都、品川区）
- Year and Date
  2015-08-01
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] DNA Methylation Status in Early Life as an Epigenetic Memory and Its Physiological Significance in Later Life.2015
- Author(s)
  Hashimoto K., Ogawa Y
- Organizer
  KEYSTONE SYMPOSIA. Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies (T2).
- Place of Presentation
  ウエスティン都ホテル（京都府、京都市）
- Year and Date
  2015-10-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 脂質異常症における甲状腺ホルモンの役割ーその基礎と臨床ー2015
- Author(s)
  橋本貢士
- Organizer
  第4回　埼玉県東部地区　サイロイドカンファレンス
- Place of Presentation
  ヒルズマーキュリー（埼玉県、越谷市）
- Year and Date
  2015-05-29
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] Peroxisome Proliferator-activated Receptor(PPAR)αを介するFibroblast Growth Factor 21(FGF21)遺伝子発現のエピゲノム制御2015
- Author(s)
  辻本和峰, 橋本貢士, 袁勲梅, 川堀健一, 小川佳宏
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  グランプラス　セント・ヴァレンタイン（山口県、下関市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] マウス肝臓におけるFGF21遺伝子発現のエピゲノム制御とその分子機構の解明2015
- Author(s)
  袁勲梅, 辻本和峰, 川堀健一, 橋本貢士, 小川佳宏
- Organizer
  BMB2015:第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県、神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] DOHaD仮説と肝臓における脂質代謝のエピゲノム制御2015
- Author(s)
  橋本貢士
- Organizer
  第88回　日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京（東京都、千代田区）
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 胎生期から乳仔期におけるマウスFibroblast Growth Factor 21(FGF21)遺伝子発現のエピゲノム制御2015
- Author(s)
  辻本和峰, 橋本貢士, 袁勲梅, 川堀健一, 小川佳宏
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] 糖尿病合併妊娠と妊娠糖尿病～周産期から一般内科への連携2015
- Author(s)
  橋本貢士
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2015-04-11
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] DNAメチル化によるエピジェネティックメモリーとDOHaD仮説2015
- Author(s)
  橋本貢士、小川佳宏
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-02
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 血中遊離サイロキシン値は肥満症減量治療の効果予測マーカーとなりうる2015
- Author(s)
  橋本貢士、小鳥真司、田上哲也、山陰一、村中和哉、田中将志、増田慎也、坊内良太郎、南勲、土屋恭一郎、吉本貴宣、河野茂夫、島津章、小川佳宏、浅原哲子
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場（愛知県、名古屋市）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 糖脂質代謝関連遺伝子発現のエピゲノム制御と先制医療への可能性2015
- Author(s)
  橋本貢士
- Organizer
  第4回　内分泌代謝懇話会
- Place of Presentation
  信州大学医学部附属病院（長野県、松本市）
- Year and Date
  2015-11-19
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 胎仔期から乳仔期におけるFibroblast Growth Factor 21(FGF21)遺伝子発現のエピゲノム制御機構2015
- Author(s)
  辻本和峰, 橋本貢士, 袁勲梅, 川堀健一, 小川佳宏
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京(東京都、千代田区）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] Epigenomic Regulation of Hepatic Lipid Metabolism and Its Clinical Application.2015
- Author(s)
  Hashimoto K., Ogawa Y
- Organizer
  12th Asian Congress of Nutrition (ACN2015)
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2015-05-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 新規バイオマーカーSiglec1によるバセドウ病の再燃、再発予測の確立2014
- Author(s)
  橋本貢士
- Organizer
  第57回日本甲状腺学会
- Place of Presentation
  ナレッジキャピタル　コングレコンベンションセンター（大阪）
- Year and Date
  2014-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-26461376
[Presentation] 胎生期から乳仔期におけるFibroblast Growth Factor (FGF) 21 遺伝子発現のエピゲノム制御2014
- Author(s)
  辻本和峰、袁勲梅、川堀健一、橋本貢士、小川佳宏
- Organizer
  第19回アディポサイエンス・シンポジウム
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] 核内受容体PPARαを介するFibroblast Growth Factor (FGF) 21 遺伝子発現のDNAメチル化制御2014
- Author(s)
  辻本和峰、橋本貢士、川堀健一、袁勲梅、小川佳宏
- Organizer
  第35回日本肥満学会
- Place of Presentation
  シーガイアコンベンションセンター
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-26350884
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達機構の解析とその特異的受容体の探索2013
- Author(s)
  橋本貢士, 石田恵美, 武田茂樹, 登丸琢也, 石井角保, 小澤厚志, 渋沢信行, 佐藤哲郎, 岡田秀一, 清水弘行, 山田正信, 森昌朋
- Organizer
  第８６回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドNesfatin-1の細胞内シグナル伝達機構の解析とその特異的受容体の探索2013
- Author(s)
  橋本貢士、森昌朋, 他
- Organizer
  第86回日本内分泌学会
- Place of Presentation
  仙台
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-22249038
[Presentation] Nesfatin-1 modulates the phosphorylation levels of cAMP response element binding protein for intracellular signaling in the neural and islet beta cell lines2013
- Author(s)
  Koshi Hashimoto, Emi Ishida, Shigeki Takeda, Tetsurou Satoh, Shuichi Okada, Masanobu Yamada, Masatomo Mori
- Organizer
  第36回内藤コンファレンス「分子からみたエネルギーバランスと摂食行動の制御」
- Place of Presentation
  シャトレーゼ　ガトーキングダム　サッポロ
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達機構の解析とその特異的受容体の探索2013
- Author(s)
  橋本貢士,石田恵美,武田茂樹,登丸琢也,石井角保,小澤厚志,渋沢信行,佐藤哲郎,岡田秀一,清水弘行,山田正信,森昌朋
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター(宮城県)
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] Nesfatin-1 modulates the phosphorylation levels of cAMP response element binding protein for intracellular signaling in the neural and islet beta cell lines2013
- Author(s)
  Koshi Hashimoto, Emi Ishida, Shigeki Takeda, Tetsurou Satoh, Shuichi Okada,Masanobu Yamada, Masatomo Mori
- Organizer
  第36回内藤コンファレンス「分子からみたエネルギーバランスと摂食行動の制御」
- Place of Presentation
  シャトレーゼガトーキングダムサッポロ(北海道)
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2012
- Author(s)
  石田恵美,橋本貢士,三浦敦子,佐藤哲郎,岡田秀一,山田正信,清水弘行,森昌朋
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2012
- Author(s)
  石田恵美, 橋本貢士, 三浦敦子, 佐藤哲郎, 岡田秀一, 山田正信, 清水弘行, 森昌朋
- Organizer
  第３９回日本神経内分泌学会学術集会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制因子nesfatin-1の受容体と細胞内シグナル伝達の探索2012
- Author(s)
  石田恵美,橋本貢士,三浦敦子,佐藤哲郎,岡田秀一,山田正信,清水弘行,森昌朋
- Organizer
  第85回日本内分泌学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制因子nesfatin-1の受容体と細胞内シグナル伝達の探索2012
- Author(s)
  石田恵美, 橋本貢士, 三浦敦子, 佐藤哲郎, 岡田秀一, 山田正信, 清水弘行, 森昌朋
- Organizer
  第８５回日本内分泌学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2012
- Author(s)
  石田恵美, 橋本貢士, 三浦敦子, 佐藤哲郎, 岡田秀一, 山田正信, 清水弘行, 森昌朋
- Organizer
  第５５回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2012
- Author(s)
  石田恵美,橋本貢士,三浦敦子,佐藤哲郎,岡田秀一,山田正信,清水弘行,森昌朋
- Organizer
  第39回日本神経内分泌学会学術集会
- Place of Presentation
  北九州国際会議場(福岡県)
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の受容体探索と細胞内シグナル伝達2011
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌プリンスホテル(北海道)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22249038
[Presentation] 摂食抑制ペプチドnesfatin-1の受容体探索と細胞内シグナル伝達2011
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌プリンスホテル（北海道）
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2011
- Author(s)
  石田恵美、橋本貢士、三浦敦子、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第38回日本神経内分泌学会
- Place of Presentation
  都道府県会館(東京都)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の受容体探索と細胞内シグナル伝達2011
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌プリンスホテル(北海道)
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2011
- Author(s)
  石田恵美、橋本貢士、三浦敦子、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第38回日本神経内分泌学会
- Place of Presentation
  都道府県会館（東京都）
- Data Source
  KAKENHI-PROJECT-23591296
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達と受容体探索2011
- Author(s)
  石田恵美、橋本貢士、三浦敦子、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第38回日本神経内分泌学会
- Place of Presentation
  都道府県会館(東京都)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22249038
[Presentation] Melanocortin 3/4 receptor is essential to the intracellular signaling pathway of nesfatin-1.2010
- Author(s)
  Emi Ishida, Koshi Hashimoto, Tetsurou satoh, Shuichi Okada, Masanobu Yamada, Hiroyuki Shimizu, Masatomo Mori
- Organizer
  14th International Congress of Endocrinology (ICE2010)
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達機構の解析2010
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山国際交流センター(岡山県)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-22249038
[Presentation] 摂食抑制ペプチドnesfatin-1に対する細胞内シグナル伝達とMelanocortin Receptorの関連2010
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第31回日本肥満学会
- Place of Presentation
  前橋テルサ(群馬県)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] チアゾリジン誘導体のNUCB2 mRNA安定性制御機構2010
- Author(s)
  山田正信,堀口和彦,梅澤良平,田口亮,橋本貢士,佐藤哲郎,岡田秀一,清水弘行,森昌朋
- Organizer
  第31回日本肥満学会
- Place of Presentation
  前橋テルサ(群馬県)
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 摂食抑制ペプチドnesfatin-1に対する細胞内シグナル伝達とMelanocortin Receptorの関連2010
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第31回日本肥満学会
- Place of Presentation
  前橋テルサ(群馬県)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22249038
[Presentation] 摂食抑制ペプチドnesfatin-1の細胞内シグナル伝達機構の解析2010
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山国際交流センター(岡山県)
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] Melanocortin 3/4 receptor is essential to the intracellular signaling pathway of nesfatin-1.2010
- Author(s)
  Emi Ishida, Koshi Hashimoto, Tetsurou Satoh, Shuichi Okada, Masanobu Yamada, Hiroyuki Shimizu, Masatomo Mori
- Organizer
  14^<th> International Congress of Endocrinology(ICE2010)(第14回国際内分泌学会議)
- Place of Presentation
  Kyoto International Conference Center(国際京都会館)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 摂食抑制蛋白nesfatin-1の細胞内シグナル伝達とMelanocortin Receptorの関与2009
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県民会館(群馬県)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] Nesfatin/Nesfatin-1はadpogenesisを抑制する2009
- Author(s)
  三浦敦子,岡田秀一,清水弘行,土屋天文,上原豊,橋本貢士,山田正信,高橋洋樹,大崎綾,大島喜八,森昌朋
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県民会館(群馬県)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 摂食抑制蛋白nesfatin-1の細胞内シグナル伝達とMelanocortin Receptorの関与2009
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第82回日本内分泌学会学術集会
- Place of Presentation
  群馬県民会館(前橋市)
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 新規摂食抑制蛋白nesfatin-1の細胞内シグナル伝達経路の解析2008
- Author(s)
  石田恵美、橋本貢士、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第35回日本神経内分泌学会
- Place of Presentation
  政策研究大学院大学(東京都)
- Year and Date
  2008-08-29
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] 新規摂食抑制蛋白nesfatin-1の細胞内シグナル伝達経路の解析2008
- Author(s)
  石田恵美、橋本貢士、堀口和彦、松本俊一、吉野聡、梅澤良平、中島康代、石塚高広、橋田哲、佐藤哲郎、岡田秀一、山田正信、清水弘行、森昌朋
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  ホテル青森(青森県)
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20591045
[Presentation] ヒトネスファチン1(NUCB2)遺伝子構造と発現制御機構の解析2008
- Author(s)
  梅澤良平,山田正信,堀口和彦,石塚高広,橋田哲,橋本貢士,佐藤哲郎,清水弘行,森昌朋
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  ホテル青森(青森県)
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-20591045

1. MOR Masatomo (80174382)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
2. YAMADA Masanobu (90261833)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
3. OKADA Shuichi (20260474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. OGAWA Yoshihiro (70291424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
5. Hara Kenji (50438701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. KAWAHORI Kenichi

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
7. SHIMIZU Hiroyuki (20251100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. INOUE Kinji (50091963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. YADA Toshihiko (60166527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAMEI Yasutomi (70300829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI MAYUMI (90596173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. YAMAZAKI Tomomi (00218439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. Yuan Xunmei (70392404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
14. Wada Michiko (80813815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 山口建 (20378772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北誠 (50767415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 浅原哲子 (80373512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 安彦郁 (20508246)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TSUJIMOTO Kazutaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
20. HANZAWA Nozomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 佐藤哲子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 山陰一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 森田純代

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 中川嘉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 島野仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hashimoto Koshi 橋本 貢士

HASHIMOTO Kohshi 橋本 貢士

橋本 真士 ハシモト コウシ

Research Projects

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Elucidation of clinicopathological significance of Siglec1 in Graves' disease and clinical application of Siglec1Principal Investigator

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「自宅で一人でできる」運動療法の患者QOL改善と糖尿病性腎症重症化抑制効果の検証

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Exercise therapy against the development of diabetic kidney disease

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Elucidation of molecular mechanism of epigenetic memory of FGF21 gene and its functional significance in vivo.Principal Investigator

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reration of subclinical hypothyroidism and fetal and maternal complications

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Elucidation of epigenetic control by fatty acid against metabolic syndrome

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Epigenetic analysis of gene expression in central nervous system of offspring derived from dam with hypothyroxinemia during pregnancyPrincipal Investigator

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Analysis of epigenetic memory of FGF21 gene in the liver

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Molecular mechanism of intracellular and in vivo function of an anorexic peptide, Nesfatin-1Principal Investigator

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Studies on signal activating systems induced by an anorexigenicappetitekine, Nesfatin-1

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Analysis of intracellular signaling pathway of an anorexic hormone 'Nesfatin-1'.Principal Investigator

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Identification of a receptor for an anorexigenic molecule, Nesfatin-1, and its signal transduction systems

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[Book] 甲状腺専門医ガイドブック2016

Author(s)

Hashimoto Koshi 橋本貢士

HASHIMOTO Kohshi 橋本貢士

橋本真士ハシモトコウシ