Ohira Masahiro 大平真裕

… Alternative Names

OHIRA MASAHIRO 大平真裕

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Researcher Number	30397947
Other IDs
Affiliation (Current)	2023: 広島大学, 病院(医), 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 広島大学, 病院(医), 助教 2016: 広島大学, 病院(医), 病院助教 2014 – 2015: 広島大学, 大学病院, 病院助教 2013: 広島大学, 医歯薬保健学研究院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / General surgery Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator NK細胞 / TRAIL / 肝細胞癌 / 肝臓 / 癌免疫 / メタボリックシンドローム / 石灰化 / ApoE / アポリポ蛋白E / エピジェネティック … More / 肝臓内免疫 / ナチュラルキラー細胞 / 肝癌 / 肝切除 / ケモカイン / GITRL / 自然免疫 / ステロイド / ＮＫ細胞 … More Except Principal Investigator 生体肝移植 / 肝門部領域胆管癌 / 移植免疫 / ネオアンチゲン / B細胞 / 免疫回避 / 腫瘍免疫 / 間接認識経路 / シグナル制御蛋 / 間接認識機構 / 遺伝子多型 / アロ免疫機構 / ヒトiPS細胞 / 免疫寛容 / シグナル制御 / 拒絶 / HLA適合移植 / 獲得免疫 / 自然免疫 / 免疫制御 / 拒絶反応 / SIRPα / HLA一致 / 他家細胞移植 / iPS細胞 Less

Investigation of impaired liver resident NK cell function in metabolic syndrome and development of an integrative therapyPrincipal Investigator
- Principal Investigator
  
  大平真裕
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hiroshima University
切除不能な肝門部領域胆管癌に対する生体肝移植で治癒に至る分子生物学的特性の解明
- Principal Investigator
  
  日比泰造
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kumamoto University
Elucidation of the mechanism of cancer immune evasion by glycan-responsive B cells and development of regulatory methods
- Principal Investigator
  
  大段秀樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Hiroshima University
Elucidation of novel rejection mechanism after HLA-matched transplantation using allogeneic iPS cells
- Principal Investigator
  
  Ohdan Hideki
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Hiroshima University
Analysis of the regulatory mechanism of liver resident NK cell function through aortic calcification factor (apolipoprotein E)Principal Investigator
- Principal Investigator
  
  大平真裕
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Hiroshima University
Analysis of the mechanism of liver resident NK cell activation through the EZH2 epigenetic regulationsPrincipal Investigator
- Principal Investigator
  
  Ohira Masahiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hiroshima University
Analysis of liver NK cell activation mechanisms through CXCL9/CXCR3 chemokine axisPrincipal Investigator
- Principal Investigator
  
  Ohira Masahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Hiroshima University
Analysis of cancer immune evasion through induction of steroid like agent, GITRL against NK cellsPrincipal Investigator
- Principal Investigator
  
  OHIRA MASAHIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Hiroshima University

All 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Impact of abdominal aortic calcification on clinical outcomes following initial hepatectomy for hepatocellular carcinoma: A retrospective cohort study2021
- Author(s)
  Imaoka Yuki、Ohira Masahiro、Sato Koki、Imaoka Kouki、Kuroda Shintaro、Tahara Hiroyuki、Kobayashi Tsuyoshi、Ide Kentaro、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  Annals of Gastroenterological Surgery
  
  Volume: 6 Issue: 1 Pages: 149-158
- DOI
  10.1002/ags3.12508
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09104
[Journal Article] Pilot study to determine the safety and feasibility of deceased donor liver natural killer cell infusion to liver transplant recipients with hepatocellular carcinoma2021
- Author(s)
  Ohira Masahiro、Hotta Ryuichi、Tanaka Yuka、Matsuura Toshiharu、Tekin Akin、Selvaggi Gennaro、Vianna Rodrigo、Ricordi Camillo、Ruiz Phillip、Nishida Seigo、Tzakis Andreas G.、Ohdan Hideki
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 71 Issue: 3 Pages: 589-599
- DOI
  10.1007/s00262-021-03005-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09104
[Journal Article] Reply: Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity -matched analysis in a single institution.2019
- Author(s)
  Nakano R, Ohira M, Kobayashi T, Ide K, Tahara H, Kuroda S, Shimizu S, Kimura T, Nagata Y, Aikata H, Chayama K, Ohdan H.
- Journal Title
  
  Surgery.
  
  Volume: 165 Issue: 5 Pages: 1054-1057
- DOI
  10.1016/j.surg.2018.10.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06269, KAKENHI-PROJECT-17K10669
[Journal Article] Utility of Doppler Ultrasonography in Liver Transplantation With Celiac Axis Compression Syndrome: A Case Report2019
- Author(s)
  Mochizuki Tetsuya、Ohira Masahiro、Hashimoto Shinji、Tahara Hiroyuki、Ide Kentaro、Kobayashi Tsuyoshi、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 51 Issue: 9 Pages: 3103-3106
- DOI
  10.1016/j.transproceed.2019.04.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Simultaneous Liver-Kidney Transplantation in Patient with a History of Heparin-Induced Thrombocytopenia: A Case Report and Literature Review2019
- Author(s)
  Taguchi Kazuhiro、Ishiyama Kohei、Ide Kentaro、Ohira Masahiro、Tahara Hiroyuki、Ohdan Hideki
- Journal Title
  
  American Journal of Case Reports
  
  Volume: 20 Pages: 980-987
- DOI
  10.12659/ajcr.916717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Everolimus enhances TRAIL‐mediated anti‐tumor activity of liver resident natural killer cells in mice2019
- Author(s)
  Saparbay Jamilya、Tanaka Yuka、Tanimine Naoki、Ohira Masahiro、Ohdan Hideki
- Journal Title
  
  Transplant International
  
  Volume: 33 Issue: 2 Pages: 229-243
- DOI
  10.1111/tri.13536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Impact of Abdominal Aortic Calcification Among Liver Transplantation Recipients2019
- Author(s)
  Imaoka Yuki、Ohira Masahiro、Nakano Ryosuke、Shimizu Seiichi、Kuroda Shintaro、Tahara Hiroyuki、Ide Kentaro、Kobayashi Tsuyoshi、Ohdan Hideki
- Journal Title
  
  Liver Transplantation
  
  Volume: 25 Issue: 1 Pages: 79-87
- DOI
  10.1002/lt.25311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Management of Refractory Ascites for Liver Transplant Candidates: A Novel Cell-free and Concentrated Ascites Reinfusion Therapy2019
- Author(s)
  Shimizu Seiichi、Ohira Masahiro、Nakano Ryosuke、Imaoka Yuki、Sato Koki、Tahara Hiroyuki、Ide Kentaro、Kobayashi Tsuyoshi、Kuroda Shintaro、Ono Hiroaki、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 51 Issue: 8 Pages: 2740-2744
- DOI
  10.1016/j.transproceed.2019.02.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Risk Factors for Refractory Ascites After Living Donor Liver Transplant2019
- Author(s)
  Sato Koki、Ohira Masahiro、Shimizu Seiichi、Imaoka Yuki、Hashimoto Shinji、Tahara Hiroyuki、Kobayashi Tsuyoshi、Kuroda Shintaro、Ide Kentaro、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 51 Issue: 5 Pages: 1516-1519
- DOI
  10.1016/j.transproceed.2019.01.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Alcohol Use Disorders Identification Test-consumption Predicts the Risk of Excessive Alcohol Consumption After Liver Transplantation2019
- Author(s)
  Yano Takuya、Ohira Masahiro、Sakamoto Ryoko、Narisada Aiko、Shimizu Seiichi、Tahara Hiroyuki、Ide Kentaro、Kobayashi Tsuyoshi、Imamura Michio、Machino Akihiko、Yamawaki Shigeto、Chayama Kazuaki、Ohdan Hideki
- Journal Title
  
  Transplantation Proceedings
  
  Volume: 51 Issue: 6 Pages: 1934-1938
- DOI
  10.1016/j.transproceed.2019.02.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Polymorphisms in TRAIL predict long-term survival and extrahepatic recurrence following initial hepatectomy for hepatocellular carcinoma2018
- Author(s)
  Imaoka Yuki、Ohira Masahiro、Yano Takuya、Nakano Ryosuke、Tanimine Naoki、Shimizu Seiichi、Kuroda Shintaro、Tahara Hiroyuki、Kobayashi Tsuyoshi、Ohdan Hideki
- Journal Title
  
  Journal of Hepato-Biliary-Pancreatic Sciences
  
  Volume: 25 Issue: 8 Pages: 370-376
- DOI
  10.1002/jhbp.573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity-matched analysis in a single institution2018
- Author(s)
  Nakano Ryosuke、Ohira Masahiro、Kobayashi Tsuyoshi、Ide Kentaro、Tahara Hiroyuki、Kuroda Shintaro、Shimizu Seiichi、Kimura Tomoki、Nagata Yasushi、Aikata Hiroshi、Chayama Kazuaki、Ohdan Hideki
- Journal Title
  
  Surgery
  
  Volume: 164 Issue: 2 Pages: 219-226
- DOI
  10.1016/j.surg.2018.03.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] Hepatic irradiation persistently eliminates liver resident NK cells2018
- Author(s)
  Nakano Ryosuke、Ohira Masahiro、Yano Takuya、Imaoka Yuki、Tanaka Yuka、Ohdan Hideki
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 6 Pages: e0198904-e0198904
- DOI
  10.1371/journal.pone.0198904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10669
[Journal Article] CD52-Negative NK Cells Are Abundant in the Liver and Less Susceptible to Alemtuzumab Treatment.2016
- Author(s)
  Hotta R, Ohira M, Matsuura T, Muraoka I, Tryphonopoulos P, Fan J, Tekin A, Selvaggi G, Levi D, Ruiz P, Ricordi C, Vianna R, Ohdan H, Waldmann H, Tzakis AG, and Nishida S.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 8 Pages: e0161618-e0161618
- DOI
  10.1371/journal.pone.0161618
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19893
[Journal Article] Intrahepatic cholangiocarcinoma coinciding with a liver metastasis from a rectal carcinoma: a case report.2016
- Author(s)
  Akabane S, Ohira M, Kobayashi T, Kuroda S, Tanimine N, Shimizu S, Tahara H, Ide K, Ishiyama K, Egi H, Tanabe K, Sentani K, Yasui W, and Ohdan H.
- Journal Title
  
  Surg Case Rep
  
  Volume: 2 Issue: 1 Pages: 94-94
- DOI
  10.1186/s40792-016-0222-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19893, KAKENHI-PROJECT-16K08691
[Journal Article] Intraoperative assessment of tissue oxygen saturation of the remnant stomach by near-infrared spectroscopy in two cases of pancreatectomy following gastrectomy.2016
- Author(s)
  Akabane S, Ohira M, Ishiyama K, Kobayashi T, Ide K, Tahara H, Kuroda S, Tanimine N, Shimizu S, Tanabe K, and Ohdan H.
- Journal Title
  
  International journal of surgery case reports
  
  Volume: 22 Pages: 75-78
- DOI
  10.1016/j.ijscr.2016.03.047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19893
[Journal Article] Elective laparoscopic deroofing to treat the spontaneous rupture of a large simple liver cyst: a case report.2016
- Author(s)
  Imaoka Y, Ohira M, Kobayashi T, Shimizu S, Tahara H, Kuroda S, Ide K, Ishiyama K, and Ohdan H.
- Journal Title
  
  Surg Case Rep
  
  Volume: 2 Issue: 1 Pages: 148-148
- DOI
  10.1186/s40792-016-0275-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝内在性NK細胞におけるAryl hydrocarbon receptor (AhR)を介した細胞内シグナル伝達の解析2021
- Author(s)
  佐藤幸毅　大平真裕
- Organizer
  第57回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 動脈硬化が肝内免疫に与える影響についての検討2021
- Author(s)
  今岡洸輝　大平真裕
- Organizer
  第57回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Clinical factors of decreased anti-tumor activity of liver-resident NK cells2021
- Author(s)
  今岡祐輝、大平真裕
- Organizer
  第32回肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Adjuvant Immunotherapy For Liver Transplant Recipients With Hepatocellular Carcinoma Using Donor Liver-derived Natural Killer Cells2021
- Author(s)
  Masahiro Ohira
- Organizer
  ATC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Novel cell-free and concentrated ascites reinfusion therapy (KM-CART) for refractory ascites in candidates for liver transplantation2021
- Author(s)
  Masahiro Ohira
- Organizer
  ILTS2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Portal hypertension abrogates TRAIL expression of liver resident NK cells via IL-332021
- Author(s)
  Yuki Imaoka, Masahiro Ohira
- Organizer
  ATC2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 外科治療における一塩基多型の役割2021
- Author(s)
  大平真裕
- Organizer
  第121回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Anti-tumor effect of liver-resident NK cells activity via the aryl hydrocarbon receptor (AhR)2020
- Author(s)
  佐藤幸毅、大平真裕
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 肝臓内自然免疫の疾患制御能および病態による影響2020
- Author(s)
  谷峰直樹, 田中友加, 大平真裕, 大段秀樹
- Organizer
  JDDW 2020
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] 肝臓癌合併生体肝移植患者に対するドナー肝臓由来活性化ナチュラルキラー細胞移入療法2020
- Author(s)
  大段秀樹, 大平真裕, 今岡祐輝, 佐藤幸毅, 田中友加
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] 肝臓移植の現状と問題点2020
- Author(s)
  大平真裕
- Organizer
  第106回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 脳死肝移植の課題と対策2020
- Author(s)
  大平真裕
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] リンパ球混合試験を用いた免疫モニタリングの肝移植免疫抑制漸減に関するCross-sectional study2020
- Author(s)
  小野紘輔, 谷峰直樹, 築山尚史, 井出隆太, 佐藤幸毅, 山根宏明, 今岡祐輝, 秋本修志, 田原裕之, 大平真裕, 井手健太郎, 小林剛, 田中友加, 大段秀樹
- Organizer
  第56回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] 肝細胞癌肝切除後におけるGNRIの臨床的意義2020
- Author(s)
  今岡祐輝、大平真裕
- Organizer
  第75回日本消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 門脈結紮による門脈圧亢進に伴う肝臓内NK細胞抗腫瘍活性の低下2020
- Author(s)
  今岡祐輝、大平真裕
- Organizer
  第120回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 新規適応基準における肝癌肝移植症例の検討2020
- Author(s)
  大平真裕
- Organizer
  第82回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 新基準導入後の肝癌に対する肝移植の現状2020
- Author(s)
  大平真裕
- Organizer
  第56回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] Adjuvant immunotherapy for liver transplant recipients with hepatocellular carcinoma using donor liver derived natural killer cells2020
- Author(s)
  Masahiro Ohira
- Organizer
  American Transplant Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09104
[Presentation] 肝移植におけるHLA抗体検査の意義エピトープ解析と免疫応答の関連性についての検討2020
- Author(s)
  井手健太郎, 大平真裕, 田原裕之, 谷峰直樹, 秋本修志, 今岡祐輝, 佐藤幸毅, 山根宏昭, 井出隆太, 築山尚史, 小野紘輔, 望月哲矢, 田中友加, 大段秀樹
- Organizer
  第56回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] Adjuvant Immunotherapeutic Approach For Liver Transplant Recipients With Hepatocellular Carcinoma Using Donor Liver Derived Natural Killer Cells2019
- Author(s)
  Ohira M, Imaoka Y, Sato K, Tahara H, Ide K, Kobayashi T, Tanaka Y, and Ohdan H.
- Organizer
  2019 American Transplant Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] 生体肝移植周術期の門脈圧がアロ免疫応答に与える影響2019
- Author(s)
  大平真裕, 橋本慎二, 尾上隆司, 今岡祐輝, 佐藤幸毅, 田口和浩, 黒田慎太郎, 田原裕之, 井手健太郎, 小林剛, 田中友加, 大段秀樹
- Organizer
  第26回日本門脈圧亢進症学会総会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] THERAPEUTIC POTENTIAL OF HEMATOPOIETIC STEM CELL-DERIVED NATURAL KILLER CELLS ON CANCER RECURRENCE AND VIRAL INFECTION AFTER LIVER TRANSPLANTATION2019
- Author(s)
  Doskali Marlen、Tanaka Y,Ohira M,Akimoto S, Ohdan H
- Organizer
  19th Congress of the European Society for Organ Transplantation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] ヒトiPS細胞からの機能性NK細胞分化誘導法の確立2019
- Author(s)
  秋本修志、田中友加, Doskali Marlen, 築山尚史, 井出隆太, Akhmet Seidakhmetov, 山根宏昭, 佐藤幸毅, 今岡祐輝, 本明慈彦, 中島一記, Jamilya Saparbay, 田口和浩, 田中飛鳥, 谷峰直樹, 森本博司, 田原裕之, 大平真裕, 井手健太郎, 小林剛, 大段秀樹
- Organizer
  第55回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] 臓器移植における免疫機能分子一塩基多型の役割.2019
- Author(s)
  大平真裕, 清水誠一, 今岡祐輝, 佐藤幸毅, 山根宏昭, 秋本修志, 田口和浩, 田中飛鳥, 黒田慎太郎, 田原裕之, 井手健太郎, 小林剛, 田中友加, 大段秀樹
- Organizer
  第119回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] Adjuvant immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation2019
- Author(s)
  大平真裕, 清水誠一, 今岡祐輝, 佐藤幸毅, 山根宏明, 秋本修志, 田口和浩, 田中飛鳥, 黒田慎太郎, 田原裕之, 井手健太郎, 小林剛, 田中友加, 大段秀樹
- Organizer
  第31回日本肝胆膵外科学会学術集会.
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] 肝細胞癌再発予後因子としてのTRAIL遺伝子一塩基多型の役割2018
- Author(s)
  今岡祐輝　大平真裕、中野亮介、清水誠一、谷峰直樹、黒田慎太郎、田原裕之、小林剛、井手健太郎、田中友加、大段秀樹
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] 肝臓癌治療における肝内在性NK細胞の可能性2018
- Author(s)
  大平真裕中野亮介　今岡祐輝　清水誠一　田原裕之　井手健太郎　小林剛　田中友加　大段秀樹
- Organizer
  第73回消化器外科学会総会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] Polymorphisms in TRAIL predict long-term survival and extrahepatic recurrence following liver resection for primary hepatocellular carcinoma.2018
- Author(s)
  Yuki Imaoka, Masahiro Ohira, Takuya Yano, Ryosuke Nakano, Naoki Tanimine, Seiichi Shimizu, Shintaro Kuroda, Hiroyuki Tahara, Tsuyoshi Kobayashi, Hideki Ohdan
- Organizer
  第30回肝胆膵外科学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] Impact of Aortic Abdominal Calcification among Living Donor Liver Transplant Recipients; A retrospective study2018
- Author(s)
  Yuki Imaoka, Masahiro Ohira, Takuya Yano, Ryosuke Nakano, Naoki Tanimine, Seiichi Shimizu, Shintaro Kuroda, Hiroyuki Tahara, Tsuyoshi Kobayashi, Yuka Tanaka, Hideki Ohdan
- Organizer
  2018 American Transplant Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] Novel immunotherapy using liver natural killer cells for preventing recurrence of hepatocellular carcinoma in liver transplantation2018
- Author(s)
  Masahiro Ohira Ryosuke Nakano, Yuki Imaoka, Yuka Tanaka, Seiichi Shimizu, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Andreas G Tzakis, Seigo Nishida, Hideki Ohdan
- Organizer
  The 17th meeting of the Society for Natural Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] ドナー肝臓由来活性化ナチュラルキラー細胞を用いた細胞移入療法による肝臓移植後重症感染症予防（第 I/II 相試験）2018
- Author(s)
  清水誠一大平真裕、中野亮介、谷峰直樹、黒田慎太郎、田原裕之、小林剛、井手健太郎、田中友加、大段秀樹
- Organizer
  第118回日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] アフェレース凍結細胞からの活性化NK細胞リモデリングと抗腫瘍・抗ウイルス効果の検討2018
- Author(s)
  田中友加, Doskali Marlen, 清水誠一, 大平真裕, 小林剛, 大段秀樹
- Organizer
  第５４回日本移植学会総会
- Data Source
  KAKENHI-PROJECT-20K20391
[Presentation] ドナー肝臓由来活性化ナチュラルキラー細胞移入療法による肝臓移植後重症感染症予防（第I/II相試験）2017
- Author(s)
  大平真裕矢野琢也　中野亮介　田中友加　大段秀樹
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] The role of Liver resident natural killer cells in treatment of hepatocellular carcinoma2017
- Author(s)
  Masahiro Ohira
- Organizer
  2017 Bridging Gaps in Oncology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10669
[Presentation] 肝癌再発予防のための肝切除後ケモカイン低下による肝臓内NK 細胞機能低下の解析2016
- Author(s)
  矢野琢也大平真裕, 中野亮介, 石山宏平, 井手健太郎, 田原裕之, 谷峰直樹, 佐伯吉弘, 清水誠一, 坂井寛, 広瀬貴行, 柳川泉一郎, 田中飛鳥, 田口和浩, 田中友加, 田代裕尊, 大段秀樹.
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-04-14
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝切除後肝臓癌再発における肝臓内NK細胞機能低下メカニズムの解明2016
- Author(s)
  矢野琢也　大平真裕, 中野亮介, 石山宏平, 井手健太郎, 田原裕之, 佐伯吉弘, 石田伸樹, 田中友加, 大段秀樹.
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2016-07-13
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝移植後肝癌再発におけるNK細胞機能脆弱化のメカニズムの解明2016
- Author(s)
  矢野琢也大平真裕, 中野亮介, 石山宏平, 井手健太郎, 田原裕之, 清水誠一, 佐伯吉弘, 坂井寛, 石田伸樹, 柳川泉一郎, 田中飛鳥, 尾上隆司, 田中友加, 大段秀樹.
- Organizer
  第52回日本移植学会総会
- Place of Presentation
  東京
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝臓切除後におけるNK細胞機能の脆弱化のメカニズム2016
- Author(s)
  矢野琢也　大平真裕, 中野亮介, 大段秀樹.
- Organizer
  第12回広島肝臓プロジェクト研究センター　シンポジウム
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] ドナー肝臓由来活性化ナチュラルキラー細胞移入療法による肝臓移植後重症感染症予防（第I/II相試験）2016
- Author(s)
  大平真裕清水誠一, 矢野琢也, 中野亮介, 堀田龍一, 田原裕之, 井手健太郎, 小林剛, 石山宏平, 田中友加, 大段秀樹
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] Corticosteroids dampen Natural Killer cell function including cytotoxicity and anti-HCV effect2016
- Author(s)
  Masahiro Ohira　Ryuichi Hotta, Takuya Yano, Ryosuke Nakano, Andreas Tzakis, Seigo Nishida, Hideki Ohdan
- Organizer
  Asian Transplantation Week 2016
- Place of Presentation
  Seoul, Korea
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] Immunotherapy using donor liver NK cells for preventing severe infection after liver transplantation2016
- Author(s)
  大平真裕　石山宏平, 小林剛, 井手健太郎, 田原裕之, 矢野琢也, 清水誠一, 中野亮介, 大段秀樹.
- Organizer
  第71回日本消化器外科学会総会
- Place of Presentation
  徳島
- Year and Date
  2016-07-13
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] Reduction in CXCL9-CXCR3 signals diminishes TRAIL-expressing liver NK cells in partially hepatectomized mice under depressed immune status.2016
- Author(s)
  Yano T　Ohira M, Nakano R, Ohdan H.
- Organizer
  26th International Congress of the Transplantation Society
- Place of Presentation
  Hong Kong, China
- Year and Date
  2016-08-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝切除による肝臓内免疫機能低下メカニズムの解明と制御2015
- Author(s)
  矢野琢也、大平真裕、大段秀樹
- Organizer
  第115回日本外科学会定期学術集会
- Place of Presentation
  名古屋国際会議場、愛知県名古屋市
- Year and Date
  2015-04-16
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] 肝切除による肝臓内免疫機能低下におけるメカニズムの解明と制御2015
- Author(s)
  矢野琢也、大平真裕、大段秀樹
- Organizer
  第51回日本移植学会総会
- Place of Presentation
  ホテル日航熊本、熊本県熊本市
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K19893
[Presentation] Significant reduction in TRAIL-expressing NK cells in remnant liver after partial hepatectomy is strongly associated with the impaired intrahepatic CXCL9–CXCR3 pathway2015
- Author(s)
  Takuya Yano, Masahiro Ohira, Hideki Ohdan
- Organizer
  2015American Transplant Congress
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2015-05-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19893

1. Ohdan Hideki (10363061)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. 田原裕之 (30423354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 井手健太郎 (50511565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 田中友加 (90432666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
5. 小林剛 (50528007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山本卓 (90244102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 日比泰造 (10338072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 武冨紹信 (70363364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 海野倫明 (70282043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 北川雄光 (20204878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 長谷川潔 (20292906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小倉靖弘 (20335251)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 波多野悦朗 (80359801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 楳田祐三 (10573735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高田泰次 (10272197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 吉住朋晴 (80363373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ABE Hiromi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 茶山一彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohira Masahiro 大平 真裕

OHIRA MASAHIRO 大平 真裕

Research Projects

Research Products

Co-Researchers

Investigation of impaired liver resident NK cell function in metabolic syndrome and development of an integrative therapyPrincipal Investigator

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切除不能な肝門部領域胆管癌に対する生体肝移植で治癒に至る分子生物学的特性の解明

Principal Investigator

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Research Institution

Elucidation of the mechanism of cancer immune evasion by glycan-responsive B cells and development of regulatory methods

Principal Investigator

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Research Institution

Elucidation of novel rejection mechanism after HLA-matched transplantation using allogeneic iPS cells

Principal Investigator

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Review Section

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Analysis of the regulatory mechanism of liver resident NK cell function through aortic calcification factor (apolipoprotein E)Principal Investigator

Principal Investigator

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Review Section

Research Institution

Analysis of the mechanism of liver resident NK cell activation through the EZH2 epigenetic regulationsPrincipal Investigator

Principal Investigator

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Research Institution

Analysis of liver NK cell activation mechanisms through CXCL9/CXCR3 chemokine axisPrincipal Investigator

Principal Investigator

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Analysis of cancer immune evasion through induction of steroid like agent, GITRL against NK cellsPrincipal Investigator

Principal Investigator

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Research Institution

[Journal Article] Impact of abdominal aortic calcification on clinical outcomes following initial hepatectomy for hepatocellular carcinoma: A retrospective cohort study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pilot study to determine the safety and feasibility of deceased donor liver natural killer cell infusion to liver transplant recipients with hepatocellular carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply: Hepatectomy versus stereotactic body radiotherapy for primary early hepatocellular carcinoma: A propensity -matched analysis in a single institution.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Utility of Doppler Ultrasonography in Liver Transplantation With Celiac Axis Compression Syndrome: A Case Report2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simultaneous Liver-Kidney Transplantation in Patient with a History of Heparin-Induced Thrombocytopenia: A Case Report and Literature Review2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Everolimus enhances TRAIL‐mediated anti‐tumor activity of liver resident natural killer cells in mice2019

Author(s)

Ohira Masahiro 大平真裕

OHIRA MASAHIRO 大平真裕