Oji Noriko 王寺典子 (下嶋典子)

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Ouji-Sageshima Noriko 王寺典子

下嶋典子

OUJI-SAGESHIMA Noriko 王寺典子(下嶋典子)

OUJI Noriko 王寺典子

SAGESHIMA Noriko 下嶋典子

王寺典子(下嶋典子) オウジノリコ

NORIKO Ouji 王寺典子

下嶋典子サゲシマノリコ

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Researcher Number	30398432
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2010 – 2024: 奈良県立医科大学, 医学部, 助教 2013: 奈良県立医科大学, 細菌学, 助授 2007 – 2008: Nara Medical University, 医学部, 助教 2006: 奈良県立医科大学, 医学部, 助手 2005: 奈良県立医科大学, 医学部, 博士研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Obstetrics and gynecology / Laboratory medicine / General surgery Except Principal Investigator General surgery / Bacteriology (including Mycology)
Keywords	Principal Investigator HLA-F / HLA-G / HLA-E / antibody / SCID / PDX / immunotherapy / HLA class Ib / 抗体療法 / 免疫療法 … More / NK細胞 / 脱落膜 / 生殖医学 / tumor / SCID-beige / 腫瘍免疫 / 悪性腫瘍 / 病理組織標本 / 腫瘍マーカー / 悪性度 / 低分化癌 / ホルマリン標本 / 大腸癌 / 診断 / 腫瘍 / 免疫染色 / ＨＬＡ－Ｆ / 非古典的ＨＬＡクラスＩ / 拒絶反応 / 移植 / 制御性T細胞 / 移植外科学 / 不育症 / 体外受精卵 / NLISA / 良好胚選定 / 胎盤 / HLAクラスI / 不妊治療 / 妊娠 / ELISA / 体外受精 / カニクイザル / 免疫寛容 / 生殖免疫 / 受精卵 / 絨毛外栄養膜細胞 / 妊娠高血圧症候群 / 免除寛容 / 生殖免除 … More Except Principal Investigator 生着 / 可溶性HLA-G / 造血幹細胞移植 / 肝移植 / 腎移植 / 移植片生着 / 移植 / HLA-G / 遺伝子多型 / Flowcytometry / ELISA / HL-G / 移植片 / リポ蛋白 / 中性糖セラミド / 腸管出血性大腸菌 / HUS / 腸管感染症 / 志賀毒素 / 免疫寛容 Less

Basic research into the practical application of immunotherapy targeting the novel immune checkpoint molecule HLA-FPrincipal Investigator
- Principal Investigator
  
  王寺典子 (下嶋典子)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nara Medical University
Development of a novel cancer immunotherapy targeting the immune checkpoint molecule, HLA-F.Principal Investigator
- Principal Investigator
  
  Ouji-Sageshima Noriko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nara Medical University
Development of new tumor diagnosis marker and new cancer immunotherapy targeting HLA-FPrincipal Investigator
- Principal Investigator
  
  Ouji-sageshima Noriko
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nara Medical University
The development of new pathologic diagnosis system using HLA-F expression on tumorPrincipal Investigator
- Principal Investigator
  
  Ouji-Sageshima Noriko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Nara Medical University
Effects of HLA-G expression and the genetic variation on graft survival - a reexamination of prior conclusions -
- Principal Investigator
  
  Ishitani Akiko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nara Medical University
Immunosuppression system by HLA-F - the development of the eliminating system of allo-reactive T cells except for regulatory T cellsPrincipal Investigator
- Principal Investigator
  
  OUJI-SAGESHIMA Noriko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nara Medical University
LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3
- Principal Investigator
  
  KITA eiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Nara Medical University
The potential role of HLA-G on transplantation immunity - examination of increasing recent reports -
- Principal Investigator
  
  ISHITANI Akiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nara Medical University
Elucidation of the mechanism how HLA-E and HLA-G form the population of decidual mononuclear cellsPrincipal Investigator
- Principal Investigator
  
  OUJI Noriko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nara Medical University
Elucidation of accumulation/differentiation mechanism of decidual NK cells by HLA-E on trophoblastsPrincipal Investigator
- Principal Investigator
  
  NORIKO Ouji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nara Medical University
HLA-E、-F、-G分子の不育症、中毒症発症への関与についてPrincipal Investigator
- Principal Investigator
  
  王寺典子 (下嶋典子)
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Nara Medical University

[Journal Article] CD8+ T-cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance2024
- Author(s)
  H, Aoki., M, Kitabatake., H, Abe., P, Xu., M, Tsunoda., S, Shichino., A, Hara., N, Ouji- Sageshima., C, Motozono., T, Ito., K, Matsushima., and S, Ueha
- Journal Title
  
  Cell reports
  
  Volume: 43 Issue: 3 Pages: 113887-113902
- DOI
  10.1016/j.celrep.2024.113887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0277, KAKENHI-PROJECT-21K07246, KAKENHI-PLANNED-22H05064, KAKENHI-PROJECT-23K24139
[Journal Article] A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4 Regulates Pulmonary Vascular Hyperpermeability through Destruction of Glycocalyx in Acute Respiratory Distress Syndrome2023
- Author(s)
  Konda Makiko、Kitabatake Masahiro、Ouji-Sageshima Noriko、Tonomura Rei、Furukawa Ryutaro、Sonobe Shota、Terada-Ikeda Chiyoko、Takeda Maiko、Kawaguchi Masahiko、Ito Toshihiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 22 Pages: 16230-16230
- DOI
  10.3390/ijms242216230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09310, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
[Journal Article] Antiviral Effect of Candies Containing Persimmon-Derived Tannin against SARS-CoV-2 Delta Strain2023
- Author(s)
  Furukawa Ryutaro、Kitabatake Masahiro、Ouji-Sageshima Noriko、Tomita Dai、Kumamoto Makiko、Suzuki Yuki、Nakano Akiyo、Nakano Ryuichi、Matsumura Yoko、Kayano Shin-ichi、Yano Hisakazu、Tamaki Shinji、Ito Toshihiro
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 8 Pages: 1636-1636
- DOI
  10.3390/v15081636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10948, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K11587
[Journal Article] Transition of Antibody Titers after SARS-CoV-2 mRNA Vaccination in Japanese Healthcare Workers2023
- Author(s)
  Kitabatake Masahiro、Ouji-Sageshima Noriko、Sonobe Shota、Furukawa Ryutaro、Konda Makiko、Hara Atsushi、Aoki Hiroyasu、Suzuki Yuki、Imakita Natsuko、Nakano Akiyo、Fujita Yukio、Shichino Shigeyuki、Nakano Ryuichi、Ueha Satoshi、Kasahara Kei、Muro Shigeo、Yano Hisakazu、Matsushima Kouji、Ito Toshihiro
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 76 Issue: 1 Pages: 72-76
- DOI
  10.7883/yoken.JJID.2022.041
- ISSN
  1344-6304, 1884-2836
- Year and Date
  2023-01-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162, KAKENHI-PROJECT-20H03474, KAKENHI-PROJECT-20K08573, KAKENHI-WRAPUP-22H04906, KAKENHI-PROJECT-23K07632
[Journal Article] The spleen is the major site for the development and expansion of inhibitor producing-cells in hemophilia A mice upon FVIII infusion developing high-titer inhibitor2023
- Author(s)
  Akihisa Oda, Shoko Furukawa, Masahiro Kitabatake, Noriko Ouji-Sageshima, Shota Sonobe, Kaoru Horiuchi, Yuto Nakajima, Kenichi Ogiwara, Ryo Goitsuka, Midori Shima, Toshihiro Ito, Keiji Nogami
- Journal Title
  
  Thrombosis research
  
  Volume: 3848 Pages: 00077-4
- DOI
  10.1016/j.thromres.2023.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07825, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21H02372
[Journal Article] Lipopolysaccharide from Yoshino cedar trees (Cryptomeria japonica) induces high levels of human macrophage polarization2022
- Author(s)
  Noriko Ouji-Sageshima, Masahiro Kitabatake, Satoki Fushimi, Satoshi Suzuki, Yuzu Fukui, Ryutaro Furukawa and Toshihiro Ito
- Journal Title
  
  Journal of Wood Science
  
  Volume: 68 Pages: 63-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07246
[Journal Article] Pure Solid Pattern of Non-Small Cell Lung Cancer and Clustered Circulating Tumor Cells2022
- Author(s)
  Sawabata Noriyoshi、Kawaguchi Takeshi、Watanabe Takashi、Yohikawa Daiki、Ouji-Sageshima Noriko、Ito Toshihiro
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 18 Pages: 4514-4514
- DOI
  10.3390/cancers14184514
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21H03021
[Journal Article] Persimmon-derived tannin has antiviral effects and reduces the severity of infection and transmission of SARS-CoV-2 in a Syrian hamster model2021
- Author(s)
  Furukawa Ryutaro、Kitabatake Masahiro、Ouji-Sageshima Noriko、Suzuki Yuki、Nakano Akiyo、Matsumura Yoko、Nakano Ryuichi、Kasahara Kei、Kubo Kaoru、Kayano Shin-ichi、Yano Hisakazu、Ito Toshihiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 23695-23695
- DOI
  10.1038/s41598-021-03149-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K11638, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
[Journal Article] Persimmon-derived tannin ameliorates the pathogenesis of ulcerative colitis in a murine model through inhibition of the inflammatory response and alteration of microbiota2021
- Author(s)
  Kitabatake Masahiro、Matsumura Yoko、Ouji-Sageshima Noriko、Nishioka Tatsuki、Hara Atsushi、Kayano Shin-ichi、Ito Toshihiro
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7286-7286
- DOI
  10.1038/s41598-021-86608-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11638, KAKENHI-PROJECT-18K11148, KAKENHI-PROJECT-21K07246
[Journal Article] Transition of antibody titers after the SARS-CoV-2 mRNA vaccine in Japanese healthcare workers2021
- Author(s)
  Kitabatake Masahiro、Ouji-Sageshima Noriko、Sonobe Shota、Furukawa Ryutaro、Konda Makiko、Hara Atsushi、Aoki Hiroyasu、Suzuki Yuki、Imakita Natsuko、Nakano Akiyo、Fujita Yukio、Shichino Shigeyuki、Nakano Ryuichi、Ueha Satoshi、Kasahara Kei、Muro Shigeo、Yano Hisakazu、Matsushima Kouji、Ito Toshihiro
- Journal Title
  
  medRxiv
  
  Volume: - Pages: 1-9
- DOI
  10.1101/2021.12.28.21268435
- Open Access
- Data Source
  KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-20K17469
[Journal Article] Vein-first Lobectomy for Lung Cancer Assessed According to the Status of Clustered Circulating Tumour Cells2021
- Author(s)
  SAWABATA NORIYOSHI、NAKANE SHIGERU、YOSHIKAWA DAIKI、WATANABE TAKASHI、KAWAGUCHI TAKESHI、OUJI-SAGESHIMA NORIKO、KUSHIBE KEIJI、ITO TOSHIHIRO
- Journal Title
  
  Cancer Diagnosis & Prognosis
  
  Volume: 1 Issue: 5 Pages: 443-450
- DOI
  10.21873/cdp.10059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07246
[Journal Article] Human Adipose-Derived Mesenchymal Stem Cells Ameliorate Elastase-Induced Emphysema in Mice by Mesenchymal-Epithelial Transition.2021
- Author(s)
  Fujioka N, Kitabatake M, Ouji-Sageshima N, Ibaraki T, Kumamoto M, Fujita Y, Hontsu S, Yamauchi M, Yoshikawa M, Muro S, Ito T.
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 8 Pages: 2783-2793
- DOI
  10.2147/copd.s324952
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17642, KAKENHI-PROJECT-21K07246, KAKENHI-PROJECT-21K08162
[Journal Article] Establishment of optimized ELISA system specific for HLA-G in body fluids.2016
- Author(s)
  Ouji-Sageshima N, Geraghty DE, Ishitani A, Hatake K, Ito T
- Journal Title
  
  HLA
  
  Volume: 88 Issue: 6 Pages: 293-299
- DOI
  10.1111/tan.12919
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461957, KAKENHI-PROJECT-15K08650
[Journal Article] sHLA-G and sHLA-I levels in follicular fluid are not associated with successful　implantation.2016
- Author(s)
  Ouji-Sageshima N, Yuui K, Nakanishi M, Takeda N, Odawara Y, Yamashita M,　Iwayama H, Awai K, Hashimoto H, Geraghty DE, Ishitani A, Hatake K, Ito T
- Journal Title
  
  J Reprod Immunol.
  
  Volume: 113 Pages: 16-21
- DOI
  10.1016/j.jri.2015.10.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08650, KAKENHI-PROJECT-25461957
[Journal Article] Selective induction of antimicrobial peptides from keratinocytes by staphylococcal bacteria.2013
- Author(s)
  Ommori R, Ouji N, Mizuno F, Kita E, Ikada Y, Asada H.
- Journal Title
  
  Microb Pathog.
  
  Volume: 56 Pages: 35-39
- DOI
  10.1016/j.micpath.2012.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590515, KAKENHI-PROJECT-23591650
[Journal Article] Soluble HLA-G is absent from human embryo cultures : a reassessment of sHLA-G detection methods.2007
- Author(s)
  Noriko Sageshima
- Journal Title
  
  Journal of Reproductive Immunology (In press)
- Data Source
  KAKENHI-PROJECT-17791132
[Journal Article] Soluble HLA-G is absent from human embryo cultures: a reassessment of sHLA-G detection methods.2007
- Author(s)
  Sageshima N, Shobu T, Awai K, Hashimoto H, Yamashita M, Takeda N, Odawara Y, Nakanishi M, Hatake K, Ishitani A.
- Journal Title
  
  J Reprod Immunol 75(1)
  
  Pages: 11-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791161
[Journal Article] Soluble HLA-G is absent from human embryo cultures:a reassessment of sHLA-G detection methods2007
- Author(s)
  Noriko Sageshima
- Journal Title
  
  Journal of Reproductive Immunlolgy 75
  
  Pages: 11-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] HLA-F blockade restored the cytotoxicity of NK cells against colorectal cancer.2023
- Author(s)
  Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
- Organizer
  第53回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] 腫瘍細胞に発現するHLA-F分子を標的とした新規免疫療法の開発2023
- Author(s)
  王寺（下嶋）典子、石谷昭子、Daniel E Geraghty、北畠正大、古川龍太郎、伊藤利洋
- Organizer
  第31回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] Antitumor effect of anti-HLA-F antibody on colon cancer in patient-derived xenografts (PDX) model.2022
- Author(s)
  Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
- Organizer
  第51回日本免疫学会学術集会（The 51th Annual Meeting of the Japanese Society for Immunology）
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] HLA-F as a new target molecule for cancer immunotherapy of colon cancer2021
- Author(s)
  Noriko Ouji-sageshima, Masahiro Kitabatake, Ryutaro Furukawa, Toshihiro Ito
- Organizer
  第50回日本免疫学会学術集会（The 50th Annual Meeting of the Japanese Society for Immunology）
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] Angiopoietin like 4 plays a critical role in the development of pulmonary fibrosis2021
- Author(s)
  Masahiro Kitabatake, Shoichiro Saito, Noriko Ouji-Sageshima, Akihisa Oda, Atsushi Hara, Tatsuro Ogawa, Shigeyuki Shichino, Satoshi Ueha, Kouji Matsushima, Toshihiro Ito
- Organizer
  第50回日本免疫学会学術集会（The 50th Annual Meeting of the Japanese Society for Immunology）
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] Histone modification enzyme SET domain bifurcated 2 (Setdb2) contributes to the pathogenesis of acute respiratory distress syndrome (ARDS) in murine model2021
- Author(s)
  Shota Sonobe, Masahiro Kitabatake, Atsushi Hara, Makiko Konda, Ryutaro Furukawa, Tomoko Nishimura, Noriko Ouji-Sagaeshima, Shiki Takamura, Toshihiro Ito
- Organizer
  第50回日本免疫学会学術集会（The 50th Annual Meeting of the Japanese Society for Immunology）
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] Persimmon-derived tannin has antiviral effects in a Syrian hamster model of SARS-CoV-2 infection.2021
- Author(s)
  Ryutaro Furukawa, Noriko Ouji Sageshima, Masahiro Kitabatake, Toshihiro Ito
- Organizer
  第50回日本免疫学会学術集会（The 50th Annual Meeting of the Japanese Society for Immunology）
- Data Source
  KAKENHI-PROJECT-21K07246
[Presentation] HLA-F分子を標的とした免疫療法の開発に向けて2019
- Author(s)
  王寺-下嶋　典子、石谷　昭子、Daniel E Geraghty、伊藤　利洋
- Organizer
  第28回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-18K07300
[Presentation] HLA-F could be a specific target for both pathological diagnosis and cancer immunotherapy of malignant colon cancer2019
- Author(s)
  Noriko Ouji-Sageshima, Tatsuki Nishioka, Masahiro Kitabatake, Daniel. E Geraghty, Akiko Ishitani, Toshihiro Ito
- Organizer
  第48回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07300
[Presentation] 悪性腫瘍におけるHLA-F発現について2019
- Author(s)
  王寺（下嶋）典子、石谷昭子、Daniel E Geraghty、伊藤利洋
- Organizer
  第16回日本組織適合性学会近畿地方会
- Data Source
  KAKENHI-PROJECT-18K07300
[Presentation] Enhanced expression of HLA-F is critically related with tumor malignancy2018
- Author(s)
  Noriko Ouji-sageshima, Akiko Ishitani, Daniel E Geraghty, Natsuko Imakita, Shota Sonobe, Masahiro Kitabatake, Toshihiro Ito
- Organizer
  The 47th Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-18K07300
[Presentation] The critical role of HLA class Ib proteins, HLA-E and HLA-F, expressed on tumor cells2017
- Author(s)
  Ouji-Sageshima Noriko, Ishitani Akiko, Imakita Natsuko, Sonobe Shota, Kitbatake Masahiro, Daniel E Geraghty, Ito Toshihiro
- Organizer
  The 46th Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] 腫瘍細胞株におけるHLA-E、-F、-G分子の発現2017
- Author(s)
  王寺-下嶋典子、石谷昭子、Daniel E Geraghty、伊藤利洋
- Organizer
  第26回日本組織適合性学会大会
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] 改良ELISA法による体外受精卵培養上清および妊婦血漿等体液中のHLA-Gの測定とその意義2016
- Author(s)
  下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
- Organizer
  第25回日本組織適合性学会大会
- Place of Presentation
  札幌市
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] 改良ELISA法による体外受精卵培養上清および妊婦血漿等体液中のHLA-Gの測定とその意義2016
- Author(s)
  王寺-下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
- Organizer
  第25回　日本組織適合性学会大会
- Place of Presentation
  北海道大学
- Year and Date
  2016-10-22
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] HLA-Gは体外受精卵培養上清および妊婦血漿等体液中に存在するのか？2016
- Author(s)
  下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
- Organizer
  第31回日本生殖免疫学会総会・学術集会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] HLA-Gは体外受精卵培養上清および妊婦血漿等体液中に存在するのか？2016
- Author(s)
  下嶋典子、Daniel E Geraghty、石谷昭子、伊藤利洋
- Organizer
  第31回日本生殖免疫学会総会学術集会
- Place of Presentation
  神戸市
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] Does HLA-G in plasma from pregnant woman inhibit the rejection of fetus?2016
- Author(s)
  Noriko　OUJI-SAGESHIMA , Akiko　ISHITANI, Daniel E GERAGHTY, Toshihiro ITO
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  宜野湾市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] Does HLA-G in plasma from pregnant woman inhibit the rejection of fetus?2016
- Author(s)
  Noriko OUJI-SAGESHIMA, Akiko ISHITANI, Daniel E Geraghty, Toshihiro ITO
- Organizer
  第45回　日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] 移植片患者末梢血におけるHLA-F、HLA-Gの発現解析―移植片生着との関連性について―2015
- Author(s)
  王寺（下嶋）典子、貝森淳哉、市丸直嗣、吉澤淳、一戸辰夫、長谷川淳、森井武志、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、伊藤利洋、Geraghty DE、石谷昭子
- Organizer
  第24回日本組織適合性学会大会
- Place of Presentation
  水戸市
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] he relation between the expression of both HLA-F and HLLA-G on PBMC from pretransplant and posttransplant patients and the graft survival.2015
- Author(s)
  Noriko　OUJI-SAGESHIMA , Akiko　ISHITANI, Daniel E GERAGHTY, Toshihiro ITO
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] 移植患者末梢血における HLA-F、HLA-Gの発現解析―移植片生着との関連性について―」2015
- Author(s)
  下嶋典子、貝森淳哉、市丸直嗣、吉澤淳、一戸辰夫、森井武志、長谷川淳、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、伊藤利洋、Daniel E Geraghty、石谷昭子
- Organizer
  第２４回日本組織適合性学会大会（水戸）
- Place of Presentation
  ホテルレイクビュー水戸
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] The relation between the expression of both HLA-F and HLA-G on PBMC from pretransplant and posttransplant patients and the graft survival.2015
- Author(s)
  Noriko Ouji-Sageshima, Daniel E Geraghty, Akiko Ishitani, Toshihiro Ito
- Organizer
  日本免疫学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08650
[Presentation] 免疫細胞上のHLA-Fの多様な発現様式2013
- Author(s)
  下嶋典子、Ni Lee、勇井克也、中西真理、貝森淳哉、矢澤浩治、吉澤淳、長谷川淳、米田龍生、森井武志、吉田克法、一戸辰夫、高原史郎、上本伸二、喜多英二、羽竹勝彦、Geraghty DE、石谷昭子
- Organizer
  第22回日本組織適合性学会
- Place of Presentation
  コラッセふくしま
- Data Source
  KAKENHI-PROJECT-24591886
[Presentation] The alternative expression patterns and conformational forms of HLA-F.2013
- Author(s)
  Sageshima N., Lee N., Ishitani A., Geraghty DE.,
- Organizer
  第42回日本免疫学会総会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-24591886
[Presentation] 移植患者末梢血リンパ球におけるHLA-G、HLA-Fの発現2012
- Author(s)
  下嶋典子　他
- Organizer
  第21回日本組織適合性学会大会
- Place of Presentation
  明治大学駿河台キャンパス
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 移植患者末梢血リンパ球におけるHLA-G、HLA-Fの発現2012
- Author(s)
  下嶋典子、勇井克也、貝森淳哉、矢澤浩治、吉澤淳、一戸辰夫、森井武志、長谷川淳、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、喜多英二、Geraghty DE、石谷昭子
- Organizer
  第21回日本組織適合性学会大会
- Place of Presentation
  明治大学駿河台キャンパス　アカデミーコモン・リバティタワー
- Data Source
  KAKENHI-PROJECT-24591886
[Presentation] 成人T細胞白血病ウイルス感染者の末梢血T細胞におけるHLA-Fの表面発現分画についての検討2012
- Author(s)
  吉岡聡、一戸辰夫、下嶋典子、菱澤方勝、大森勝之、Geraghty DE、石谷昭子、高折晃史
- Organizer
  第21回日本組織適合性学会
- Place of Presentation
  東京
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] 移植患者末梢血リンパ球におけるHLA-G、HLA-Fの発現2012
- Author(s)
  下嶋典子、勇井克也、貝森淳哉、矢澤浩治、吉澤淳、一戸辰夫、森井武志、長谷川淳、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、喜多英二、Geraghty DE、石谷昭子
- Organizer
  第21回日本組織適合性学会大会
- Place of Presentation
  明治大学駿河台キャンパス　アカデミーコモン・リバティタワー
- Data Source
  KAKENHI-PROJECT-22591413
[Presentation] Geraghty DE、石谷昭子移植患者末梢血リンパ球におけるHLA-G、HLA-Fの発現2012
- Author(s)
  下嶋典子、勇井克也、貝森淳哉、矢澤浩治、吉澤淳、一戸辰夫、森井武志、長谷川淳、米田龍生、高原史郎、上本伸二、吉田克法、羽竹勝彦、喜多英二
- Organizer
  第21回日本組織適合性学会大会
- Place of Presentation
  明治大学駿河台キャンパスアカデミーコモン・リバティタワー
- Year and Date
  2012-09-15
- Data Source
  KAKENHI-PROJECT-22591413
[Presentation] 志賀毒素と特異受容体Gb3及びLDLの関連解析2011
- Author(s)
  笠原一規、東伸岳、下嶋典子、喜多英二
- Organizer
  日本細菌学会関西支部総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-23590515
[Presentation] HLA-E with HLA-G-derived peptide on trophoblast binds CD56^<bright> NK cells strongly and may contribute the accumulation of NK cells in decidua.2010
- Author(s)
  王寺典子
- Organizer
  第14回国際免疫学会議
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22791541
[Presentation] HLA-E with HLA-G-derived peptide on trophoblast binds CD56^<bright> NK cells strongly and may contribute the accumulation of NK cells in decidua2010
- Author(s)
  王寺典子
- Organizer
  第14回国際免疫学会議
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22791541
[Presentation] Absence of sHLA-G from embryo cultures -a reassessment of detection methods2008
- Author(s)
  王寺典子(下嶋典子)
- Organizer
  EMBIC Workshop on sHLA-G and Implantation
- Place of Presentation
  イギリス
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 可溶性HLA-G測定法の問題点と体外受精分野への影響2008
- Author(s)
  王寺典子
- Organizer
  第7回日本組織適合性学会近畿地方会
- Place of Presentation
  大阪・参天製薬株式会社本社
- Year and Date
  2008-02-07
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 可溶性HLA-G抗原測定法の問題点と体外受精分野への影響2008
- Author(s)
  王寺典子(下嶋典子)
- Organizer
  第6回日本組織適合性学会近畿地方会
- Place of Presentation
  大阪
- Year and Date
  2008-02-02
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 受精卵着床における可溶性HLA-G抗原の意義2008
- Author(s)
  王寺典子(下嶋典子)
- Organizer
  第23回日本生殖免疫学会
- Place of Presentation
  富山富山国際会議場
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 可溶性HLA-G抗原測定法の問題点-卵胞液中の可溶性HLA-G抗原の意義-2008
- Author(s)
  王寺典子(下嶋典子)
- Organizer
  第17回日本組織適合性学会大会
- Place of Presentation
  大阪大阪国際会議場
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 受精卵着床における可溶性HLA-G抗原の意義2008
- Author(s)
  王寺典子
- Organizer
  第23回日本生殖免疫学会
- Place of Presentation
  富山・富山国際会議場
- Year and Date
  2008-12-07
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 可溶性HLA-G抗原測定法の問題点-卵胞液中の可溶性HLA-G抗原の意義-2008
- Author(s)
  王寺典子
- Organizer
  第17回日本組織適合性学会大会
- Place of Presentation
  大阪・大阪国際会議場
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] Absence of sHLA-G from embryo cultures-a reassessment of detection methods2008
- Author(s)
  王寺典子
- Organizer
  EMBIC Workshop on sHLA-G and Implantation
- Place of Presentation
  イギリス・Mansfield college
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 旧世界ザルにおけるHLA-G、HLA-Fホモログの発現2007
- Author(s)
  王寺典子(下嶋典子)
- Organizer
  第16回日本組織適合性学会大会
- Place of Presentation
  京都
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 旧世界ザルにおけるHLA-G、HLA-Fホモログの発現2007
- Author(s)
  王寺典子
- Organizer
  第16回日本組織適合性学会大会
- Place of Presentation
  京都・ぱ・る・るプラザ京都
- Year and Date
  2007-09-09
- Data Source
  KAKENHI-PROJECT-19791161
[Presentation] 可溶性HLA-G抗原検出法の確立
- Author(s)
  王寺（下嶋）典子、赤崎正佳、Geraghty DE、喜多英二、石谷昭子、羽竹勝彦、伊藤利洋
- Organizer
  第29回日本生殖免疫学会総会
- Place of Presentation
  伊藤国際学術研究センター、東京都文京区
- Year and Date
  2014-12-13 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-24591886
[Presentation] 可溶性HLA-G抗原検出法の確立
- Author(s)
  王寺（下嶋）典子、赤崎正佳、Geraghty DE、喜多英二、石谷昭子、羽竹勝彦、伊藤利洋
- Organizer
  第29回日本生殖免疫学会総会
- Place of Presentation
  伊藤国際学術研究センター、東京都文京区
- Year and Date
  2014-12-12 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] 体液中の可溶性HLA-G抗原検出法の確立
- Author(s)
  王寺（下嶋）典子、中西真理、貝森淳哉、市丸直嗣、吉澤淳、長谷川淳、米田龍生、森井武志、吉田克法、一戸辰夫、高原史郎、上本伸二、赤崎正佳、Geraghty DE、伊藤利洋、石谷昭子、喜多英二、羽竹勝彦
- Organizer
  第23回日本組織適合性学会大会
- Place of Presentation
  長崎大学熱帯医学研究所、長崎県長崎市
- Year and Date
  2014-09-13 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] Establishment of the detection system of soluble HLA-G in body fluids
- Author(s)
  Noriko　OUJI-SAGESHIMA , Akiko　ISHITANI, Daniel E GERAGHTY, Toshihiro ITO
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館、京都府京都市
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25461957
[Presentation] 体液中の可溶性HLA-G抗原検出法の確立
- Author(s)
  王寺（下嶋）典子、中西真理、貝森淳哉、市丸直嗣、吉澤淳、長谷川淳、米田龍生、森井武志、吉田克法、一戸辰夫、高原史郎、上本伸二、赤崎正佳、Geraghty DE、伊藤利洋、石谷昭子、喜多英二、羽竹勝彦
- Organizer
  第23回日本組織適合性学会大会
- Place of Presentation
  長崎大学熱帯医学研究所、長崎県長崎市
- Year and Date
  2014-09-13 – 2014-09-15
- Data Source
  KAKENHI-PROJECT-24591886
[Presentation] Establishment of the detection system of soluble HLA-G in body fluids
- Author(s)
  Noriko　OUJI-SAGESHIMA , Akiko　ISHITANI, Daniel E GERAGHTY, Toshihiro ITO
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館、京都府京都市
- Year and Date
  2014-12-10 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-24591886

1. ISHITANI Akiko (40112544)

# of Collaborated Projects: 4 results

# of Collaborated Products: 24 results
2. ICHINOHE Tatsuo (80314219)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. UEMOTO Shinji (40252449)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. TAKAHARA Shiro (70179547)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
5. YOSHIDA Katsunori (50192422)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
6. 伊藤利洋 (00595712)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
7. MORII Takeshi (70264851)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. KITA eiji (90133199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. MIZUNO Fumiko (70271202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. MORII Takeshi (70268451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Obayashi Chiho (90223940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Nakai Tokiko (00619538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 武田真幸 (20510928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NOGAMI Keiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. ODA Akihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 北畠正大

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. 園部奨太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 本園千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 松村羊子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 栢野新市

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
21. 藤田幸男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oji Noriko 王寺 典子 (下嶋 典子)

Ouji-Sageshima Noriko 王寺 典子

下嶋典子

OUJI-SAGESHIMA Noriko 王寺 典子(下嶋典子)

OUJI Noriko 王寺 典子

SAGESHIMA Noriko 下嶋 典子

王寺 典子(下嶋典子) オウジ ノリコ

NORIKO Ouji 王寺 典子

下嶋 典子 サゲシマ ノリコ

Research Projects

Research Products

Co-Researchers

Basic research into the practical application of immunotherapy targeting the novel immune checkpoint molecule HLA-FPrincipal Investigator

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Development of a novel cancer immunotherapy targeting the immune checkpoint molecule, HLA-F.Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Development of new tumor diagnosis marker and new cancer immunotherapy targeting HLA-FPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of new pathologic diagnosis system using HLA-F expression on tumorPrincipal Investigator

Principal Investigator

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Research Institution

Effects of HLA-G expression and the genetic variation on graft survival - a reexamination of prior conclusions -

Principal Investigator

Project Period (FY)

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Research Institution

Immunosuppression system by HLA-F - the development of the eliminating system of allo-reactive T cells except for regulatory T cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

LDL-dependent cytotoxicity of Shiga toxin in the cells devoid of Gb3

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

The potential role of HLA-G on transplantation immunity - examination of increasing recent reports -

Principal Investigator

Project Period (FY)

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Research Institution

Elucidation of the mechanism how HLA-E and HLA-G form the population of decidual mononuclear cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of accumulation/differentiation mechanism of decidual NK cells by HLA-E on trophoblastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HLA-E、-F、-G分子の不育症、中毒症発症への関与についてPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] CD8+ T-cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance2024

Author(s)

Oji Noriko 王寺典子 (下嶋典子)

Ouji-Sageshima Noriko 王寺典子

OUJI-SAGESHIMA Noriko 王寺典子(下嶋典子)

OUJI Noriko 王寺典子

SAGESHIMA Noriko 下嶋典子

王寺典子(下嶋典子) オウジノリコ

NORIKO Ouji 王寺典子

下嶋典子サゲシマノリコ

[Journal Article] sHLA-G and sHLA-I levels in follicular fluid are not associated with successful　implantation.2016