KAGIYA Tadayoshi 鍵谷忠慶

Researcher Number	30405774
Other IDs
Affiliation (Current)	2022: 岩手医科大学, 歯学部, 助教
Affiliation (based on the past Project Information) *help	2007 – 2020: 岩手医科大学, 歯学部, 助教 2007: 若手医科大学, 歯学部, 助教 2005 – 2006: Iwate Medical University, Assistant, 歯学部, 助手
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Orthodontic/Pediatric dentistry / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Morphological basic dentistry / Dental engineering/Regenerative dentistry
Keywords	Principal Investigator microRNA / 破骨細胞 / 骨吸収 / エクソソーム / 細胞外小胞 / 歯周病 / ナノ粒子 / リキッドバイオプシー / マイクロアレイ / Exosomes … More / Osteoclasts / Bone / バイオマーカー / 癌 / シグナル伝達 / 歯学 / 病理学 / 発現抑制 / Microvesicles / Osteoblasts / Macrophages / Microarray / Orthodontics / 骨芽細胞 / exosomes / microvesicles / RANKL / THP-1 / RAW264.7 / MicroRNA / Osteoclast / Exosome / Osteoblast / TNF-alpha / 骨リモデリング / 時計遺伝子 / 炎症性サイトカイン / マクロファージ / Extracellular Vesicles / Periodontal Disease / 炎症 / 免疫 / 糖尿病 / インスリン抵抗性 … More Except Principal Investigator 歯の発生 / 歯学 / 細胞・組織 / apical bud / stem cell niche / tooth germ / calcification / lipogenesis / Meckel's cartilage / development / 象牙芽細胞 / リアルタイムイメージング / RECK / ROCK / 細胞極性 / マトリックスメタロプロテアーゼ / アメロゲニン / 発生・分化 / シグナル伝達 / 歯胚発生 / Rhoシグナリング / real time imaging / slice culture / FGF9 / NGF / スライスカルチャー / ネスチン / 歯根形成 / ヘルトヴィッヒ上皮鞘 / 器官培養 / EGF / サービカルループ / 上皮成長因子 / GFP / 歯根形戌 / 生体材料 / 遷移金属イオン / 遺伝子 / 銅イオンシャペロン / 銅イオントランスポーター / 損傷遺伝子修復酵素 / Fgf10 / Fgf9 / エナメル上皮幹細胞 / 間葉系幹細胞 / 歯の再生 / niche / 上皮間葉相互作用 / Fgf 10 / Fgf 9 / dental epithelial stem cells / mesenchymal stem cells / bioengineered teeth / Meckel' cartilage / osteoclast / osteoclasts / differentiation Less

糖尿病は歯周病特異的エクソソームで増悪するか？Principal Investigator
- Principal Investigator
  
  鍵谷忠慶
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Iwate Medical University
Do Exosomes play a role in Alveolar Bone Loss in Periodontal Disease?Principal Investigator
- Principal Investigator
  
  Kagiya Tadayoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Iwate Medical University
Are microRNAs in Exosomes Involved in Alveolar Bone Loss in Periodontal Disease?Principal Investigator
- Principal Investigator
  
  KAGIYA Tadayoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Iwate Medical University
Development of a New Treatment in Orthodontics by Focusing on Clock Genes which are Regulated by microRNAs.Principal Investigator
- Principal Investigator
  
  KAGIYA TADAYOSHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Iwate Medical University
Evaluation on clarification of transport system of transition metallic ions inside body-defense cells and its association with bio-safety
- Principal Investigator
  
  TAIRA Masayuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Iwate Medical University
Research for developing drug to inhibit malignant melanoma bone metastasis by targeting Wnt5a signalingPrincipal Investigator
- Principal Investigator
  
  KAGIYA Tadayoshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Iwate Medical University
Study on mechanisms of odontoblasts processes formation and dentin development
- Principal Investigator
  
  HARADA Hidemitsu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University
Cell dynamics in transition stage from crown to tooth root formation and effects of growth factors in development of Hertwig epithelial root sheath
- Principal Investigator
  
  FUJIWARA Naoki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University
Regeneration of tooth germ using dental epithelial stem cells and dental papilla mesenchymal stem cells in rodent incisors
- Principal Investigator
  
  HARADA Hidemitsu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University
  Osaka University
The studies of the tooth germ differentiation and the transformation of chondrocytes in vitro.
- Principal Investigator
  
  NAWA Tokio
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Iwate Medical University

[Book] TNF-α Promotes Extracellular Vesicle Release by Human Macrophage-like Cells and Alters Vesicle MicroRNA Expression Profiles. In: Exosomes and Microvesicles: Role in Disease and Clinical Applications2020
- Author(s)
  Tadayoshi Kagiya
- Publisher
  Nova Science Publishers
- ISBN
- Data Source
  KAKENHI-PROJECT-17K11682
[Book] Roles of MicroRNAs in Osteoclast Differentiation and Function. In: Osteoclasts: Cell Biology, Functions and Related Diseases.2015
- Author(s)
  Tadayoshi Kagiya
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-26462853
[Book] Microarrays: Principles, Applications and Technologies.2014
- Author(s)
  Kagiya T and Taira M
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-23593042
[Book] Nova Science Publishers2014
- Author(s)
  Kagiya T, Taira M
- Publisher
  A New Application for Microarrays : Analysis of Global MicroRNA Expression Profiles in the Extracellular Microvesicles of Human Macrophage-like Cells.In : Rogers JV, editor. Microarrays : Principles, Applications and Technologies
- Data Source
  KAKENHI-PROJECT-23593042
[Journal Article] MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease2016
- Author(s)
  Tadayoshi Kagiya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 17(8)
- DOI
  10.3390/ijms17081317
- NAID
  120005894249
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462853
[Journal Article] MicroRNAs and Osteolytic Bone Metastasis: The Roles of MicroRNAs in Tumor-Induced Osteoclast Differentiation.2015
- Author(s)
  Tadayoshi Kagiya
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 4 (9) Pages: 1741-1752
- DOI
  10.3390/jcm4091741
- NAID
  120005894250
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462853
[Journal Article] Expression of MicroRNAs in the Extracellular Microvesicles of Murine Osteoclasts.2013
- Author(s)
  Kagiya T
- Journal Title
  
  Journal of Oral Tissue Engineering
  
  Volume: 10 Pages: 142-150
- NAID
  130004941089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593042
[Journal Article] Expression profiling of microRNAs in RAW264.7 cells treated with a combination of tumor necrosis factor alpha and RANKL during osteoclast differentiation2013
- Author(s)
  Kagiya T
- Journal Title
  
  J Periodontal Res
  
  Volume: 48 Pages: 373-385
- DOI
  10.1111/jre.12017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593042
[Journal Article] Expression of MicroRNAs in the Extracellular Microvesicles of Murine Osteoclasts2013
- Author(s)
  Kagiya T, Taira M
- Journal Title
  
  J Oral Tissue Engin
  
  Volume: 10(3) Pages: 142-150
- NAID
  130004941089
- URL
  https://iwatemed.repo.nii.ac.jp/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593042
[Journal Article] Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper (2+) ions.2011
- Author(s)
  Taira M, Shimoyama Y, Kagiya T, et.al.
- Journal Title
  
  Dent Mater J.
  
  Volume: (印刷中)
- NAID
  10029136627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper(2+) ions2011
- Author(s)
  Taira M., Shimoyama, Y., Kagiya, T., Sasaki, M., Nezu, T., Harada, H. and Kimura, S.
- Journal Title
  
  Dental Mater. J.
  
  Volume: 30 Pages: 293-299
- NAID
  10029136627
- URL
  http://dx.doi.org/10.4012/dmj.2010-088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Quantitative real-time RT-PCR analyses of DNA-damage. recovery-related gene expressions of mouse macrophage-like cell line RAW264 when exposed to IC50 nickel ions2011
- Author(s)
  Taira, M., Kagiya, T., Sasaki, M. and Kimura, S.
- Journal Title
  
  Nano-Biomedicine
  
  Volume: 3 Pages: 294-299
- NAID
  130004555811
- URL
  https://www.jstage.jst.go.jp/article/nano/3/2/3_2_294/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Proteome analyses of human macrophages exposed to low cytotoxic IC90 Cu(2+) ions2011
- Author(s)
  Taira, M., Shimoyama Y., Kagiya, T., Sasaki, M., Nezu, T., Harada, H., Kimura, S.
- Journal Title
  
  Dental Materials Journal
  
  Volume: 30(受理済み)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Proteome analyses of human macrophages exposed to low cytotoxic IC90 copper (2+) ions.2011
- Author(s)
  Taira M, Shimoyama Y, Kagiya T, Sasaki M, Nezu T, Harada H, Kimura S.
- Journal Title
  
  Dent Mater J. in press
- NAID
  10029136627
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles2010
- Author(s)
  Taira, M., Kagiya, T., Harada, H., Sasaki, M., 他4名
- Journal Title
  
  J.Mater.Sci.Mater.Med. 21
  
  Pages: 267-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.2010
- Author(s)
  Taira M, Kagiya T, et. al.
- Journal Title
  
  J Mater Sci Mater Med. Vol.21
  
  Pages: 267-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles2010
- Author(s)
  Taira, M., Kagiya, T., Harada, H., Sasaki, M., 他4名
- Journal Title
  
  J. Mater. Sci. Mater. Med.
  
  Volume: 21 Pages: 267-275
- DOI
  10.1007/s10856-009-3834-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.2010
- Author(s)
  Taira M, Kagiya T, Harada H, Sasaki M, Kimura S, Narushima T, Nezu T, Araki Y.
- Journal Title
  
  J Mater Sci Mater Med. 21
  
  Pages: 267-275
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] First-stage genome-wide gene expression analyses of human mesenchymal stem cells exposed to IC50 Ni(2+) ions2009
- Author(s)
  Taira, M., Kagiya, T., Sasaki, M., Sasaki, K., Saitoh, S., 他4名
- Journal Title
  
  J. Oral Tissue Eng
  
  Volume: 7 Pages: 107-120
- NAID
  130004456605
- URL
  https://www.jstage.jst.go.jp/article/jarde/7/2/7_2_107/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] First-stage Genome-Wide Gene Expression Analyses of Human Mesenchymal Stem Cells Exposed to IC50 Ni(2+) ions.2009
- Author(s)
  Taira M, Kagiya T, Sasaki M, Sasaki K, Saitoh S, Nezu T, Harada H, Kimura S, Araki Y.
- Journal Title
  
  J Oral Tissue Eng. 7(2)
  
  Pages: 107-120
- NAID
  130004456605
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] Expression of osteogenic proteins during the intrasplenic transplantation of Meckel's chondrocytes: A histochemical and immunohistochemical study.2009
- Author(s)
  Ishizeki K, Kagiya T, Fu, jiwara N, Otsu K, Harada H
- Journal Title
  
  Arch Histol Cytol 72(1)
  
  Pages: 1-12
- NAID
  10025867939
- Data Source
  KAKENHI-PROJECT-19390466
[Journal Article] Reduction of Egf signaling decides transition from crown to root in the development of mouse molars.2009
- Author(s)
  ujiwara N, Akimoto T, Otsu K, Kagiya T, Ishizeki K, Harada H.
- Journal Title
  
  J Exp Zoolog B Mol Dev Evol 312B(5)
  
  Pages: 486-94
- Data Source
  KAKENHI-PROJECT-19390466
[Journal Article] Preparation and in vivo evaluation of apatite/collagen packed composite by alternate immersion method and Newton press.2009
- Author(s)
  Taira, M., Nezu, T., Sasaki, K., Saitoh, S., Kagiya, T., Harada, H., Takada, Y., Araki, Y.
- Journal Title
  
  J. Biomed. Mater. Res. B Appl. Biomater. 90
  
  Pages: 566-573
- Data Source
  KAKENHI-PROJECT-19390466
[Journal Article] First-stage Genome-Wide Gene Expression Analyses of Huma-n Mesenchymal Stem Cells Exposed to IC50 Ni (2+) ions.2009
- Author(s)
  Taira M, Kagiya T, et. al.
- Journal Title
  
  J Oral Tissue Eng. Vol.7(2)
  
  Pages: 107-120
- NAID
  130004456605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791830
[Journal Article] Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.2009
- Author(s)
  Taira, M., Kagiya, T., Harada, H., Sasaki, M., Kimura, S., Narushima, T., Nezu, T., Araki, Y.
- Journal Title
  
  J. Mater. Sci. Mater. Med. 20
- Data Source
  KAKENHI-PROJECT-19390466
[Journal Article] First-stage genome-wide gene expression analyses of human mesenchymal stem cells exposed to IC50 Ni(2+) ions2009
- Author(s)
  Taira, M., Kagiya, T., Sasaki, M., Sasaki, K., Saitoh, S., 他4名
- Journal Title
  
  J.Oral Tissue Eng. 7
  
  Pages: 107-120
- NAID
  130004456605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390526
[Journal Article] Gene expression analyses of human macrophage phagocytizing sub-micro titanium particles by allergy DNA chip (Genopal).2009
- Author(s)
  Taira M, Nezu T, Sasaki M, Kimura S, Kagiya T, Harada H, Narushima T, Araki Y
- Journal Title
  
  Biomed Mater Eng 19(1)
  
  Pages: 63-70
- Data Source
  KAKENHI-PROJECT-19390466
[Journal Article] Molecular mechanisms regulating transition from crown to root formation in the development of mouse molars2008
- Author(s)
  Fujiwara, N., Kagiya, T., Ishizeki, K., Harada, H.
- Journal Title
  
  J Oral Bioscience 50
  
  Pages: 154-159
- NAID
  10027103936
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592128
[Journal Article] Egf signaling regulates transition from crown to root formation in the development of mouse molars2008
- Author(s)
  Fujiwara, N., Akimoto, T., Kagiya, T., Ishizeki, K., Harada, H.
- Journal Title
  
  Journal of Experimental Zoology-Molecular and Developmental Evolution, Dec. 17(e-Pub)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592128
[Journal Article] Egf prevents formation of Hertwig's epithelial root sheath during developing mouse molar tooth in vitro2007
- Author(s)
  Fujiwara, N., Kagiya, T., Ishizeki, K. and Harada, H.
- Journal Title
  
  Eur Cell Mat. 14(Proceeding Suppl. 2)
  
  Pages: 54-54
- Data Source
  KAKENHI-PROJECT-19592128
[Journal Article] A role of Wnt5a in continuously growing mice incisors2007
- Author(s)
  Kagiya, T., Fujiwara, N., Ishizeki, K. Xiao, J. and Harada, H.
- Journal Title
  
  Eur Cell Mat. 14, Suppl Proceeding 2 p91
- Data Source
  KAKENHI-PROJECT-19592128
[Journal Article] in vitro adipocytic conversion in Meckel's chondrocytes in response to a fatty acid-containing medium.2006
- Author(s)
  Ishizeki, K., Kagiya T., Fujiwara N., Harada H.
- Journal Title
  
  Arch. Histol., Cytol. 69
  
  Pages: 163-171
- NAID
  10020623509
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390527
[Presentation] マクロファージ由来の細胞外小胞エクソソームのTNF-αによる変化について2020
- Author(s)
  鍵谷忠慶
- Organizer
  日本生化学会東北支部第86回例会
- Data Source
  KAKENHI-PROJECT-17K11682
[Presentation] Tumor necrosis factor alphaとLipopolysaccharideが口腔上皮細胞のmicroRNA発現に与える影響について2018
- Author(s)
  鍵谷忠慶
- Organizer
  第60回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11682
[Presentation] MicroRNAs are Potential Therapeutic Targets and Biomarkers for Alveolar Bone Loss in Periodontal Disease2017
- Author(s)
  Tadayoshi Kagiya
- Organizer
  15th Annual Congress of International Drug Discovery Science and Technology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11682
[Presentation] TNF-αはヒトマクロファージ様細胞の細胞外小胞の分泌を促進する2017
- Author(s)
  鍵谷忠慶
- Organizer
  第59回歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17K11682
[Presentation] 癌の骨転移におけるmicroRNAの関与の可能性について2016
- Author(s)
  鍵谷忠慶
- Organizer
  九燦團会
- Place of Presentation
  九州大学医学部百年講堂（福岡市）
- Year and Date
  2016-08-11
- Data Source
  KAKENHI-PROJECT-26462853
[Presentation] TNF-αはマクロファージのmicroRNAを含む細胞外小胞エクソソームの分泌を促進しその発現プロファイルを変化させる2016
- Author(s)
  鍵谷忠慶
- Organizer
  第57回日本組織細胞化学会学術集会
- Place of Presentation
  杏林大学（三鷹市）
- Year and Date
  2016-09-03
- Data Source
  KAKENHI-PROJECT-26462853
[Presentation] 破骨細胞分化に関与するmicroRNAについて2015
- Author(s)
  鍵谷忠慶
- Organizer
  第18回癌と骨病変研究会
- Place of Presentation
  東京都
- Year and Date
  2015-11-13
- Invited
- Data Source
  KAKENHI-PROJECT-26462853
[Presentation] 破骨細胞分化過程における細胞外小胞でのmicroRNAの発現について2015
- Author(s)
  鍵谷　忠慶
- Organizer
  第120回日本解剖学会全国学術集会　第92回日本生理学会大会　　合同大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-03-22
- Data Source
  KAKENHI-PROJECT-26462853
[Presentation] microRNAを介した破骨細胞分化制御について2014
- Author(s)
  鍵谷忠慶
- Organizer
  岩手医科大学歯学研究セミナー
- Place of Presentation
  盛岡市
- Year and Date
  2014-03-04
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] 破骨細胞分化において重要と考えられるmicroRNAについて2013
- Author(s)
  鍵谷忠慶、中山貴博、安藤禎紀、藤村朗
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  高松市
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] 赤色蛍光強発現TGマウスの蛍光分布2012
- Author(s)
  安藤禎紀、古川真司、桑島幸紀、鍵谷忠慶、藤村朗、三浦廣行
- Organizer
  第117回日本解剖学会全国学術集会
- Place of Presentation
  甲府市
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] NF-α/RANKL誘導性破骨細胞におけるmicroRNAの発現について2012
- Author(s)
  鍵谷忠慶、中山貴博
- Organizer
  第117回日本解剖学会全国学術集会
- Place of Presentation
  甲府市
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] 骨代謝におけるmicroRNAの役割について2012
- Author(s)
  鍵谷忠慶
- Organizer
  東夷塾
- Place of Presentation
  甲府市
- Year and Date
  2012-03-26
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] NF-α/RANKL誘導性破骨細胞における microRNA の発現について2012
- Author(s)
  鍵谷　忠慶
- Organizer
  第117回日本解剖学会全国学術集会
- Place of Presentation
  甲府市
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] マクロファージが銅イオンに暴露された時のmicroRNAの発現について2011
- Author(s)
  鍵谷忠慶, 他3名
- Organizer
  第54回歯科基礎医学会学術大会
- Place of Presentation
  岐阜市
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-21390526
[Presentation] ヒト遊離歯肉下口腔上皮下リンパ管構築2011
- Author(s)
  安藤禎紀、鍵谷忠慶、藤村朗
- Organizer
  第116回日本解剖学会全国学術集会
- Place of Presentation
  震災のため誌上開催
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 破骨細胞分化におけるmicroRNAの関与について2011
- Author(s)
  鍵谷忠慶、安藤禎紀、藤村朗
- Organizer
  岩手医科大学歯学会第71回例会
- Place of Presentation
  岩手医科大学(盛岡市)
- Year and Date
  2011-02-26
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] マクロファージが銅イオンに暴露された時のmicroRNAの発現について2011
- Author(s)
  鍵谷忠慶、平雅之、安藤禎紀、藤村朗
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜市
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] ヒト遊離歯肉下口腔上皮下リンパ管構築2011
- Author(s)
  安藤禎紀、鍵谷忠慶、藤村朗
- Organizer
  第116回日本解剖学会全国学術集会
- Place of Presentation
  (震災のため誌上開催)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] マクロファージが銅イオンに暴露された時のmicroRNAの発現について2011
- Author(s)
  鍵谷忠慶、平雅之, 他2名
- Organizer
  第53回歯科基礎医学会学術大会
- Place of Presentation
  岐阜市
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-21390526
[Presentation] 破骨細胞分化におけるmicroRNAの発現解析2010
- Author(s)
  鍵谷忠慶、安藤禎紀、藤村朗
- Organizer
  日本解剖学会第56回東北・北海道連合支部学術集会
- Place of Presentation
  旭川医科大学(旭川市)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 間葉系幹細胞と血管内皮細胞との相互作用2010
- Author(s)
  大津圭史、藤原尚樹、石関清人、鍵谷忠慶、原田英光
- Organizer
  第115回日本解剖学会全国学術集会
- Place of Presentation
  岩手県水産会館(盛岡市)
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 破骨細胞におけcalpain-slingshotを介したアクチンリング制御について2010
- Author(s)
  鍵谷忠慶、安藤禎紀、藤村朗、三浦廣行
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 破骨細胞におけるcalpain-slingshotを介したアクチンリング制御について2010
- Author(s)
  鍵谷忠慶、安藤禎紀、藤村朗、三浦廣行
- Organizer
  第52回歯科基礎医学会学術大会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] GFPマウスを用いたメッケル軟骨の形質転換のイメージング解析2009
- Author(s)
  石関清人、大津圭史、鍵谷忠慶、藤原尚樹、原田英光
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟市)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 歯の再生を目的としたiPS細胞の上皮2009
- Author(s)
  大津圭史、石関清人、鍵谷忠慶、藤原尚樹、原田英光
- Organizer
  間葉細胞への分化誘導と分離培養第114回日本解剖学会総会・全国学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 銅イオンのマクロファージへ及ぼす細胞障害作用について第114回日本解剖学会総会2009
- Author(s)
  鍵谷忠慶、秋元義、大津圭史、藤原尚樹、石関清人、原田英光, 吉田康夫、平雅之
- Organizer
  全国学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Rhoキナーゼによるエナメル芽細胞の極性制御機構2009
- Author(s)
  大津圭史、藤原尚樹、石関清人、鍵谷忠慶、佐々木憲明、原田英光
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟市)
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 天然低分子化合物を用いた歯根・歯周組織再生.2009
- Author(s)
  米澤貴之, 太田正人, 藤原尚樹, 車柄允, 照屋俊明, 鍵谷忠慶, 原田英光, 矢ヶ崎一三, 永井和夫, 禹済泰
- Organizer
  第21回日本動物細胞工学会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] ヘルトヴィッヒ上皮鞘形成過程におけるサービカルループでの細胞動態2009
- Author(s)
  原田英光、石関清人、大津圭史、鍵谷忠慶、藤原尚樹
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] ヘルトヴィッヒ上皮鞘形成過程におけるサービカルループでの細胞動態2009
- Author(s)
  原田英光、石関清人、大津圭史、鍵谷忠慶、藤原尚樹
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  朱鷺メッセ(新潟市)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21791830
[Presentation] 歯の再生を目的としたiPS細胞の上皮、間葉細胞への分化誘導と分離培養2009
- Author(s)
  大津圭史、藤原尚樹、石関清人、鍵谷忠慶、原田英光
- Organizer
  第114回日本解剖学会学術集会
- Place of Presentation
  岡山理科大学(岡山)
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] GFPマウスを用いたメッケル軟骨細胞の形質転換のイメージング解析2009
- Author(s)
  石関清人、大津圭史、鍵谷忠慶、藤原尚樹、原田英光
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 歯胚組織中の細胞動態を観察するためのimaging systemの開発2009
- Author(s)
  藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
- Organizer
  第114回日本解剖学会学術集会
- Place of Presentation
  岡山理科大学(岡山)
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] Rho.キナーゼによるエナメル芽細胞の極性制御機構2009
- Author(s)
  大津圭史、藤原尚樹、石関清人、鍵谷忠慶、佐々木憲明, 原田英光
- Organizer
  第51回歯科基礎医学会学術大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 歯胚組織中の細胞動態を観察するためのimaging systemの開発第114回日本解剖学会総会2009
- Author(s)
  藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
- Organizer
  全国学術大会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] マウス切歯幹細胞を用いた歯の再生2008
- Author(s)
  原田英光、鍵谷忠慶、藤原尚樹、石関清人
- Organizer
  第113回日本解剖学会全国学術集会シンポジウム
- Place of Presentation
  大分大学(大分市)
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] ヘルトヴィッヒ上皮鞘細胞の不死化2008
- Author(s)
  秋元義、藤原尚樹、鍵谷忠慶、石関清人、原田英光
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Place of Presentation
  大分
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] ヘルトビィッヒ上皮鞘細胞の不死化2008
- Author(s)
  秋元義、藤原尚樹、鍵谷忠慶、石関清人、原田英光
- Organizer
  第113回日本解剖学会総会、全国学術集会
- Place of Presentation
  大分大学(大分)
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] マウス切歯の組織幹細胞を用いた歯の再生. シンポジウムS28細胞分化と口腔領域における再生2008
- Author(s)
  原田英光、藤原尚樹、鍵谷忠慶、石関清人
- Organizer
  第113回日本解剖学会総会・全国学術集会
- Place of Presentation
  大分
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] 破骨細胞の細胞死におけるカルパインの関与について2008
- Author(s)
  鍵谷忠慶、佐々木憲明、石関清人、藤原尚樹、原田英光
- Organizer
  岩手医科大学歯学会第66回例
- Place of Presentation
  岩手医大(盛岡)
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 高濃度銅イオンによるマクロファージの細胞形態変化と障害作用の評価2008
- Author(s)
  平雅之, 鍵谷忠慶, 原田英光, 佐々木実, 木村重信
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  昭和大学(東京)
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 歯冠から歯根形成への移行過程におけるEGF signalingの役割2008
- Author(s)
  藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  昭和大学(東京)
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 破骨細胞の細胞死におけるカルパインの関与について2008
- Author(s)
  鍵谷忠慶、佐々木憲明、石関清人、藤原尚樹、原田英光
- Organizer
  岩手医科大学歯学会第66回例会
- Place of Presentation
  岩手医大(盛岡)
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] マウス切歯の組織幹細胞を用いた歯の再生2008
- Author(s)
  原田英光、藤原尚樹、鍵谷忠慶、石関清人
- Organizer
  第7回日本再生医療学会シンポジウム
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] マウス切歯の組織幹細胞を用いた歯の再生. シンポジウム20歯の再生研究の最前線2008
- Author(s)
  原田英光、藤原尚樹、鍵谷忠慶、石関清人
- Organizer
  第7回日本再生医療学会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-13
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] 歯冠から歯根形成への移行過程におけるEGFsignalingの役割2008
- Author(s)
  藤原尚樹、大津圭史、秋元義、鍵谷忠慶、石関清人、原田英光
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  昭和大学(東京)
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] メッケル軟骨の形質転換の意味するもの2008
- Author(s)
  石関清人、鍵谷忠慶、藤原尚樹、原田英光
- Organizer
  第50回歯科基礎医学会学術大会
- Place of Presentation
  昭和大学(東京)
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Hertwig's epithelial root sheath is made of outer enamel epithelium2008
- Author(s)
  Fujiwara, N., Kagiya, T., Ishizeki, K., Otsu, K., Akimoto and T., Harada, H.
- Organizer
  Gordon Research Conference on Craniofacial Morphogenesis & Tissue Regeneration
- Place of Presentation
  Ciocco, Barga, Italy
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] Mechanisms on maintenance of dental stem cells and how to make a biotooth.2007
- Author(s)
  Harada, H., Fujiwara, N., Y-Tamaki, T., Kagiya, T., Tabata, Y., Ishizek.K.
- Place of Presentation
  Tsukuba, Japan
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] 石関清人歯の幹細胞の維持機構の解明から歯の再生への展開第30回日本分子生物学会2007
- Author(s)
  原田英光、藤原尚樹、鍵谷忠慶
- Organizer
  第80回日本生化学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Calpain阻害剤を用いた破骨細胞のアポトーシス抑制第112回日本解剖学会総会2007
- Author(s)
  鍵谷忠慶、佐々木憲明、石関清人、藤原尚樹、原田英光
- Organizer
  全国学術集会
- Place of Presentation
  大阪市
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Mechanisms on maintenance of dental stem cells and how to make a biotooth.2007
- Author(s)
  H Harada N Fujiwara, T Yokohama-Tamaki, T Kagiya, Y Tabata, K Ishizaki
- Organizer
  lst ABMC
- Place of Presentation
  Tsukuba, Japan
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Mechanisms on maintenance of dental stem cells and how to make a biotooth2007
- Author(s)
  Harada, H., Fujiwara, N., Yokohama-Tamaki, T., Kagiya, T., Tabata, Y. and Ishizeki. K.
- Organizer
  1^<st> Asian Biomaterials Congress(Integrated Congress of 6^<th> Asian International Symposium on Biomaterials and 8^<th> Asian Symposium on Biomedical Materials)
- Place of Presentation
  Tsukuba, Japan
- Year and Date
  2007-12-08
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] EGF prevents formation of Hertwig' s epithelial root sheath during developing mouse molar tooth in vitro.2007
- Author(s)
  Naoki Fujiwara, Tadayoshi Kagiya, Kiyoto Ishizeki, Hidemitsu Harada
- Organizer
  9th International Conference on Tooth Morphogenesis and Differentiation 2007
- Place of Presentation
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] A role of Wnt5a in continuously growing mice incisors2007
- Author(s)
  Kagiya, T., Fujiwara, N., Ishizeki, K., Xiao, J. and Harada, H.
- Organizer
  9th International Conference on Tooth Morphogenesis and Differentiation 2007
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2007-09-06
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] メッケル軟骨細胞の脾臓内移植からみた細胞の形質転換2007
- Author(s)
  石関清人, 原田英光, 鍵谷忠慶, 藤原尚樹
- Organizer
  第49回歯科基礎医学会学術大会・総会
- Place of Presentation
  札幌市
- Year and Date
  2007-08-30
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] A role of Wnt5a in continuously growing mice incisors.2007
- Author(s)
  Kagiya, T., Fujiwara, N., Ishizeki, K., J Xiao, Harada, H.
- Organizer
  9th International Conference on Tooth Morphogenesis and Differentiation
- Place of Presentation
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] ヘルトビッヒの上皮鞘(HERS)形成過程の新規仮説と歯根発生メカニズム. サテライトシンポジウムSS5-5、ヘルトヴィッヒ上皮鞘(HERS)と歯根発生のバイオロジー2007
- Author(s)
  原田英光, 鍵谷忠慶, 藤原尚樹, 石関清人
- Organizer
  第49回歯科基礎医学会学術大会
- Place of Presentation
  札幌
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] ヘルトビッヒの上皮鞘(HERS)形成過程の新規仮説と歯根発生メカニズム2007
- Author(s)
  原田英光, 鍵谷忠慶, 藤原尚樹, 石関清人
- Organizer
  第49回歯科基礎医学会学術大会サテライトシンポジウム
- Place of Presentation
  札幌市
- Year and Date
  2007-08-29
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] EGF prevent formation of Hertwig's epithelial root sheath during developing mouse molar tooth in vitro2007
- Author(s)
  Fujiwara, N., Kagiya, T., Ishizeki, K. and Harada, H.
- Organizer
  9th International Conference on Tooth Morphogenesis and Differentiation 2007
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] 歯の幹細胞の維持機構の解明から歯の再生への展開2007
- Author(s)
  原田英光、藤原尚樹、鍵谷忠慶、石関清人
- Organizer
  ワークショップ5W6、歯の発生・再生の分子メカニズム、第30回日本分子生物学会年会と第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] メッケル軟骨の局所形態発生とその運命2007
- Author(s)
  石関清人、鍵谷忠慶、藤原尚樹、原田英光
- Organizer
  第112回日本解剖学会全国学術集会シンポジウム
- Place of Presentation
  大阪市
- Year and Date
  2007-03-28
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] Wnt5aノックアウトマウス歯胚の組織学所見について2007
- Author(s)
  鍵谷忠慶、藤原尚樹、石関清人、原田英光
- Organizer
  岩手医科大学歯学会第36回例会
- Place of Presentation
  盛岡市
- Year and Date
  2007-02-24
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] ヘルトビッヒの上皮鞘(HERS)形成過程の新規仮説と歯根発生メカニズム2007
- Author(s)
  原田英光, 鍵谷忠慶, 藤原尚樹石関清人
- Organizer
  第49回歯科基礎医学会学術大会サテライトシンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19390466
[Presentation] A role of Wnt5a in continuously growing mice incisors.2007
- Author(s)
  Kagiya, T., et. al.
- Organizer
  9th International Conference on Tooth Morphogenesis and Differentiation 2007.
- Place of Presentation
  Zurich,Switzerland
- Year and Date
  2007-09-08
- Data Source
  KAKENHI-PROJECT-19592128
[Presentation] 破骨細胞分化において重要と考えられるmicroRNA について
- Author(s)
  鍵谷忠慶
- Organizer
  第118回日本解剖学会全国学術集会
- Place of Presentation
  高松市
- Data Source
  KAKENHI-PROJECT-23593042
[Presentation] microRNAを介した破骨細胞分化制御について
- Author(s)
  鍵谷　忠慶
- Organizer
  岩手医科大学　歯学研究セミナー
- Place of Presentation
  盛岡市
- Invited
- Data Source
  KAKENHI-PROJECT-23593042

1. ISHIZEKI Kiyoto (50057775)

# of Collaborated Projects: 7 results

# of Collaborated Products: 44 results
2. FUJIWARA Naoki (20190100)

# of Collaborated Projects: 6 results

# of Collaborated Products: 46 results
3. HARADA Hidemitsu (70271210)

# of Collaborated Projects: 5 results

# of Collaborated Products: 55 results
4. OHSHIMA Hayato (70251824)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAIRA Masayuki (60179398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
6. ANDO Yoshinori (40583662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. FUJIMURA Akira (80173459)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
8. NEZU Akashi (40264056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. SASAKI Minoru (40187133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. NAKAYAMA Takahiro (70599208)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MIURA Hiroyuki (00048563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. NAWA Tokio (50020748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 豊澤悟 (30243249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 脇坂聡 (40158598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 遠藤真 (50347879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAGIYA Tadayoshi 鍵谷 忠慶

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糖尿病は歯周病特異的エクソソームで増悪するか？Principal Investigator

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Do Exosomes play a role in Alveolar Bone Loss in Periodontal Disease?Principal Investigator

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Are microRNAs in Exosomes Involved in Alveolar Bone Loss in Periodontal Disease?Principal Investigator

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Development of a New Treatment in Orthodontics by Focusing on Clock Genes which are Regulated by microRNAs.Principal Investigator

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Evaluation on clarification of transport system of transition metallic ions inside body-defense cells and its association with bio-safety

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Research for developing drug to inhibit malignant melanoma bone metastasis by targeting Wnt5a signalingPrincipal Investigator

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Study on mechanisms of odontoblasts processes formation and dentin development

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Cell dynamics in transition stage from crown to tooth root formation and effects of growth factors in development of Hertwig epithelial root sheath

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Regeneration of tooth germ using dental epithelial stem cells and dental papilla mesenchymal stem cells in rodent incisors

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The studies of the tooth germ differentiation and the transformation of chondrocytes in vitro.

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[Book] TNF-α Promotes Extracellular Vesicle Release by Human Macrophage-like Cells and Alters Vesicle MicroRNA Expression Profiles. In: Exosomes and Microvesicles: Role in Disease and Clinical Applications2020

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[Book] Roles of MicroRNAs in Osteoclast Differentiation and Function. In: Osteoclasts: Cell Biology, Functions and Related Diseases.2015

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[Book] Microarrays: Principles, Applications and Technologies.2014

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[Book] Nova Science Publishers2014

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KAGIYA Tadayoshi 鍵谷忠慶