Hiromura Makoto 廣村信

… Alternative Names

廣村信ヒロムラマコト

HIROMURA Makoto 廣村信

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Researcher Number	30411036
Other IDs
External Links
Affiliation (Current)	2025: 第一薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 第一薬科大学, 薬学部, 准教授 2010: 独立行政法人理化学研究所, 神戸研究所・分子イメージングセンター, 協力研究員 2005 – 2006: 京都薬科大学, 薬学部, PD
Review Section/Research Field	Except Principal Investigator Basic Section 49050:Bacteriology-related / Chemistry / Science and Engineering / Applied pharmacology
Keywords	Except Principal Investigator 亜鉛錯体 / 2成分転写制御系 / 肺炎桿菌 / コリスチン耐性 / 抗菌薬多剤耐性 / drug delivery system / hypoglycemic effect / insulin-mimetic action / zinc complex / vanadium complex … More / metabolic syndrome / diabetes mellitus / インスリンシグナル伝達経路 / アリキシン / 亜鉛 / バナジウム / 金属錯体 / インスリン注射 / 糖尿病治療薬 / ポルフィリン錯体 / ドラッグデリバリー系 / 糖尿病治療 / ドラッグデリバリーシステム / 血糖降下作用 / インスリン様作用 / バナジウム錯体 / メタボリックシンドローム / 糖尿病 / α-グルコシダーゼ阻害 / 膵アミラーゼ阻害 / 膵リパーゼ阻害 / 体内動態 / 2型糖尿病 / メタボリック症候群 / 肥満抑制作用 Less

二成分転写制御系CrrBによる多剤耐性化とコリスチン耐性化のメカニズムの解明
- Principal Investigator
  
  小川和加野
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Daiichi University, College of Pharmaceutical Sciences
Development of inorganic zinc-containing medicines with anti-obesity action
- Principal Investigator
  
  YASUI Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto Pharmaceutical University
Development of Metal Complexes with Antidialetic Effect
- Principal Investigator
  
  SAKURAI Hiromu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Science and Engineering
  Chemistry
- Research Institution
  Kyoto Pharmaceutical University

All 2023 2007 2006 2005

All Journal Article Presentation

[Journal Article] Mutation in crrB encoding a sensor kinase increases expression of the RND-type multidrug efflux pump KexD in Klebsiella pneumoniae2023
- Author(s)
  Dodan Hayata、Hiromura Makoto、Ni Rui Ting、Matsubara Futoshi、Kuroda Teruo、Ogawa Wakano
- Journal Title
  
  Gene
  
  Volume: 878 Pages: 147543-147543
- DOI
  10.1016/j.gene.2023.147543
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07016
[Journal Article] Molecular mechanism for antidiabetic activity of [meso-tetrakis(4-sulfonatophenyl)- porphyrinato]oxovanadium(IV) [VO(tpps)] complex : studies on Akt phosphorylation and GLUT4 translocation in 3T3-L1 adipocytes2007
- Author(s)
  Wanny Basuki, Makoto Hiromura, Hiromu Sakurai
- Journal Title
  
  Bull. Chem. Soc. Jpn. (in press)
- NAID
  10019848775
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Insulinomimetic Zn complex (Zn(opt)_2) enhances insulin signaling pathway in 3T3-L1 adipocytes2007
- Author(s)
  Wanny Basuki, Makoto Hiromura, Hiromu Sakurai
- Journal Title
  
  J. Inorg. Biochem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes2006
- Author(s)
  Wanny Basuki, Makoto Hiromura, Yusuke Adachi, Kojiro Tayama, Masakazu Hattori, Hiromu Sakurai
- Journal Title
  
  Biochem. Biophys. Res. Commun. 349(3)
  
  Pages: 1163-1170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1 in the liver microsomes of streptozotocin-induced type 1 diabetic rats2005
- Author(s)
  Sayuri Kataoka, Makoto Hiromura, Hiroyuki Yasui, Hiromu Sakurai
- Journal Title
  
  Trace Nutri. Res. 22
  
  Pages: 19-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats2005
- Author(s)
  Sayuri Kataoka, Hiroyuki Yasui, Makoto Hiromura, Hiromu Sakurai
- Journal Title
  
  Life Sci. 77(22)
  
  Pages: 2814-2829
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Journal Article] High potent antidiabetic vanadyl and zinc complexes2005
- Author(s)
  Hiromu Sakurai, Yusuke Adachi, Makoto Hiromura
- Journal Title
  
  5th International Symposium on Trace Elements in Human : New Perspectives 16(4)
  
  Pages: 126-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16001003
[Presentation] 肺炎桿菌のRND型多剤排出ポンプKexD発現に関与する因子の検討2023
- Author(s)
  小川和加野、廣村信、堂段駿太、松原大、黒田照夫
- Organizer
  第35回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-21K07016

1. YASUI Hiroyuki (20278443)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. YOSHIKAWA Yutaka (20388028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SAKURAI Hiromu (30065916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 小嶋良種 (40047139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小川和加野 (90397878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

Hiromura Makoto 廣村 信

廣村 信 ヒロムラ マコト

HIROMURA Makoto 廣村 信

Research Projects

Research Products

Co-Researchers

二成分転写制御系CrrBによる多剤耐性化とコリスチン耐性化のメカニズムの解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of inorganic zinc-containing medicines with anti-obesity action

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Metal Complexes with Antidialetic Effect

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Mutation in crrB encoding a sensor kinase increases expression of the RND-type multidrug efflux pump KexD in Klebsiella pneumoniae2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Molecular mechanism for antidiabetic activity of [meso-tetrakis(4-sulfonatophenyl)- porphyrinato]oxovanadium(IV) [VO(tpps)] complex : studies on Akt phosphorylation and GLUT4 translocation in 3T3-L1 adipocytes2007

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Insulinomimetic Zn complex (Zn(opt)_2) enhances insulin signaling pathway in 3T3-L1 adipocytes2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enhancement of insulin signaling pathway in adipocytes by oxovanadium(IV) complexes2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1 in the liver microsomes of streptozotocin-induced type 1 diabetic rats2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Effect of insulin-mimetic vanadyl sulfate on cytochrome P450 2E1-dependent p-nitrophenol hydroxylation in the liver microsomes of streptozotocin-induced type 1 diabetic rats2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] High potent antidiabetic vanadyl and zinc complexes2005

Author(s)

Journal Title

Description

Data Source

[Presentation] 肺炎桿菌のRND型多剤排出ポンプKexD発現に関与する因子の検討2023

Author(s)

Organizer

Data Source

Hiromura Makoto 廣村信

廣村信ヒロムラマコト

HIROMURA Makoto 廣村信