SHIRAHATA Tatsuya 白畑辰弥

Researcher Number	30414056
Affiliation *help	2012 – 2013 : 北里大学, 薬学部, 講師 2008 – 2009 : 北里大, 薬学部, 助教 2009 : Kitasato University, 薬学部, 講師 2008 : Kitasato University, 薬学部, 助教 – 2007 : 北里大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Chemical pharmacy
Keywords	Principal Investigator ワクチン / 配糖化 / 合成化学 / 配当化 / マイクロフローリアクター / 機合成 / ワクチンアジュバント / 糖鎖合成 / 糖鎖 / 有機合成

Study on synthetic sapnonins, candidates of vaccine adjuvant, via construction of glycosidic bond at C28 ester moiety by using microflow reactor.Principal Investigator
- Principal Investigator
  
  SHIRAHATA Tatsuya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University
Development of novel type of sequential glycosylation for creation of the synthetic vaccine.Principal Investigator
- Principal Investigator
  
  SHIRAHATA Tatsuya
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kitasato University

All 2013 2012 2010 2008

All Journal Article Presentation

[Journal Article] Toward the Synthesis of Phomoidride D2013
- Author(s)
  Murphy, G. K.; Shirahata, T.; Hama, N.; Bedermann, A.; Dong, P.; McMahon, T. C.; Twenter, B.. M.; Spiegel, D. A.; McDonald, I.. M.; Taniguchi, N.; Inoue, M.; Wood, J. L.
- Journal Title
  
  J. Org. Chem.
  
  Volume : 78 Pages : 477-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790021
[Journal Article] Towar d the Synthesis of Phomoidr ide D2013
- Author(s)
  Murphy, Graham K.; Shirahata, Tatsuya; Hama, Naoto; Bedermann, Aaron; Dong, Ping; McMahon, Taravis C.; Twenter, Barry. M.; Spiegel, David A.; McDonald, Ivar. M.; Taniguchi, Nobuaki; Inoue, Munenori; Wood, John. L.
- Journal Title
  
  Journal of Organic Chemistry
  
  Volume : 78 Pages : 477-489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790021
[Journal Article] Asymmetric total synthesis of neoxaline2013
- Author(s)
  Tetsuya Ideguchi, Takeshi Yamada, Tatsuya Shirahata, Tomoyasu Hirose, Akihiro Sugawara, Yoshinori Kobayashi, Satoshi Omura, Toshiaki Sunazuka
- Journal Title
  
  J Am Chem Soc
  
  Volume : 135 Pages : 12568-12571
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23105012, KAKENHI-PUBLICLY-24102527, KAKENHI-PROJECT-24790021, KAKENHI-PROJECT-24790022, KAKENHI-PROJECT-25460020, KAKENHI-PROJECT-25860010
[Journal Article] Asymmetr ic Total Synthesis of Neoxaline2013
- Author(s)
  Ideguchi, Tetsuya; Yamada, Takeshi; Shirahata, Tatsuya; Hirose, Tomoyasu; Sugawara, Akihiro; Kobayashi, Yoshinori;?mura, Satoshi; Sunazuka, Toshiaki
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume : 135(34) Pages : 12568-12571
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790021
[Journal Article] Petersson, George A.;?mura, Satoshi; Shiomi, Kazuro : Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventor s of ar bekacin resistance in MRSA2013
- Author(s)
  Takata, Keiko; Iwatsuki, Masato; Yamamoto, Tsuyoshi; Shirahata, Tatsuya; Nonaka, Kenichi; Masuma, Rokuro; Hayakawa, Yoichi; Hanaki, Hideaki; Kobayashi, Yoshinori
- Journal Title
  
  Organic Letters
  
  Volume : 15(18) Pages : 4678-4681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790021
[Journal Article] Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventors of arbekacin resistance in MRSA2013
- Author(s)
  Takata, Keiko; Iwatsuki, Masato; Yamamoto, Tsuyoshi; Shirahata, Tatsuya; Nonaka, Kenichi; Masuma, Rokuro; Hayakawa, Yoichi; Hanaki, Hideaki; Kobayashi, Yoshinori; Petersson, George A.; Omura, Satoshi; Shiomi, Kazuro
- Journal Title
  
  Organic Letters
  
  Volume : 15 Pages : 4678-4681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790021, KAKENHI-PROJECT-25560407
[Journal Article] Oral adjuvant activity for nasal influenza vaccines causes by combination of nvo trihydroxy fatty acid stereoisomers from the tuber of Pinellia ternate2010
- Author(s)
  Nagai, TakapuAi ; Shimizu, Yuriko ; Shirahata. Tatsuya ; Sunazuka, Toshiaki ; Kipohara, Himaki ; Omura, Saloshi ; Yamada Haruki
- Journal Title
  
  International Immunopharmacology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790017
[Journal Article] Improved catalytic and stereoselective glycosylation with glycosyl N-trichloroacetylcarbamate : application to various 1-hydroxy sugars2010
- Author(s)
  Shirahata, Tatsuva ; Matsuo, Jun-ichi : Teruya, Satoko ; Akimoto, Nanao ; Kurimoto, Taku ; Kaji, Eisuke ; Omura, Satoshi
- Journal Title
  
  Carbohydrate Research 345
  
  Pages : 740-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790017
[Journal Article] Improved catalytic and stereoselective glycosylation with glycosyl N-trichloroacetylcarbamate: application to various 1-hydroxy sugars2010
- Author(s)
  Shirahata, Tatsuya; Matsuo, Jun-ichi; Teruya, Satoko; Akimoto, Nanao; Kurimoto, Taku; Kaji, Eisuke; Omura, Satoshi
- Journal Title
  
  Carbohydrate Research Vol345
  
  Pages : 740-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790017
[Journal Article] Oral adjuvant activity for nasal influenza vaccines causes by combination of two trihydroxy fatty acid stereoisomers from the tuber of Pinellia ternate2010
- Author(s)
  Nagai, Takayuki; Shimizu, Yuriko; Shirahata, Tatsuya; Sunazuka, Toshiaki; Kiyohara, Hiroaki; Omura, Satoshi; Yamada Haruki
- Journal Title
  
  International Immunopharmacology Vol10
  
  Pages : 665-661
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790017
[Presentation] 1-OH糖を使用した脱水的グリコシル化による三糖合成2013
- Author(s)
  白畑辰弥,小島麻実,照屋智子,鰻池将吾,横山将来,松尾淳一,牧野一石,砂塚敏明,梶英輔,大村智,小林義典
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜・パシフィコ横浜(横浜)
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-In?uenza Virus Antibody Titer against Second Nasal Inoculation of In?uenza HA Vaccine of Oleanolic acid Sapnonins2013
- Author(s)
  Tatsuya Shirahata, Hiroaki Kiyohara, Nozomu Hirata, Masaki Yokoyama, Tatsuya Katsumi, Takashi Nishino, Kazuishi Makino, Takayuki Nagai, Haruki Yamada, Eisuke Kaji, Yoshinori Kobayashi
- Organizer
  Gordon Research Conferences Heterocyclic Comounds
- Place of Presentation
  (Newport, RI, USA)
- Year and Date
  2013-06-17
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-In?uenza Virus Antibody Titer against Second Nasal Inoculation of In?uenza HA Vaccine of Oleanolic acid Sapnonins2013
- Author(s)
  Tatsuya Shirahata, Hiroaki Kiyohara, Nozomu Hirata, Masaki Yokoyama, Tatsuya Katsumi, Takashi Nishino, Kazuishi Makino, Takayuki Nagai, Haruki Yamada, Eisuke Kaji, Yoshinori Kobayashi
- Organizer
  International Conference on the Chemistry of Antibiotics and other bioactive compounds
- Place of Presentation
  (ICCA-13, Yamanashi, Japan)
- Year and Date
  2013-09-25
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-Influenza Virus Antibody Titer against Second Nasal Inoculation of Influenza HA Vaccine of Oleanolic acid Sapnonins2013
- Author(s)
  Tatsuya Shirahata, Hiroaki Kiyohara, Nozomu Hirata, Masaki Yokoyama, Tatsuya Katsumi, Takashi Nishino, Kazuishi Makino, Takayuki Nagai, Haruki Yamada, Eisuke Kaji, Yoshinori Kobayashi
- Organizer
  Gordon Research Conferences Heterocyclic Comounds
- Place of Presentation
  Salve Regina University, Newport, RI, USA
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-Influenza Virus Antibody Titer against Second Nasal Inoculation of Influenza HA Vaccine of Oleanolic acid Sapnonins2013
- Author(s)
  Tatsuya Shirahata, Hiroaki Kiyohara, Nozomu Hirata, Masaki Yokoyama, Tatsuya Katsumi, Takashi Nishino, Kazuishi Makino, Takayuki Nagai, Haruki Yamada, Eisuke Kaji, Yoshinori Kobayashi
- Organizer
  International Conference on the Chemistry of Antibiotics and other bioactive compounds
- Place of Presentation
  Yamanashi, Japan
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] マイクロフローリアクターを利用した桂皮酸エステルを有するサポニンの合成研究2012
- Author(s)
  白畑辰弥，勝見達也，横山将来，平田望, 永井隆之，清原寛章，山田陽城，梶英輔，小林義典
- Organizer
  第64回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  長岡（新潟）
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] マイクロフローリアクターを利用した桂皮酸エステルを有するサポニンの合成研究2012
- Author(s)
  白畑辰弥，勝見達也，横山将来，平田望, 永井隆之，清原寛章，山田陽城，梶英輔，小林義典
- Organizer
  Glyco Tokyo
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] マイクロフローリアクターを利用した桂皮酸エステルを有するサポニンの合成研究2012
- Author(s)
  白畑辰弥,勝見達也,横山将来,平田望,永井隆之,清原寛章,山田陽城,梶英輔,小林義典
- Organizer
  Glyco Tokyo 2012
- Place of Presentation
  東京・慶應大学薬学部(東京)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] マイクロフローリアクターを利用した桂皮酸エステルを有するサポニンの合成研究2012
- Author(s)
  白畑辰弥,勝見達也,横山将来,平田望,永井隆之,清原寛章,山田陽城,梶英輔,小林義典
- Organizer
  第64回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  新潟・長岡科学技術大学(新潟、長岡)
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-24790021
[Presentation] グリコシルカルバメートとカルバモチオエートを用いた簡便な糖鎖連結の方法論の開発2010
- Author(s)
  白畑辰弥, 小島麻実, 照屋智子, 横山将来, 松尾淳一, 牧野一石, 砂塚敏明, 小林義典, 梶英輔, 大村智
- Organizer
  日本薬学会第130年会(岡山)
- Place of Presentation
  岡山・桃太郎アリーナ
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790017
[Presentation] グリコシルカルバメートとカルバモチオエートを用いた簡便な糖鎖連結の方法論の開発2010
- Author(s)
  白畑辰弥, 小島麻実, 照屋智子, 横山将来, 松尾淳一, 牧野一石, 砂塚敏明, 小林義典, 梶英輔, 大村智
- Organizer
  日本薬学会第130年会(岡山)
- Place of Presentation
  岡山・桃太郎アリーナ
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-20790017
[Presentation] 4位に桂皮酸エステルを有するグルコース誘導体の合成2008
- Author(s)
  白畑辰弥
- Organizer
  第54回有機合成化学協会関東支部シンポジウム
- Place of Presentation
  新潟大学工学部
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-20790017

1. Sunazuka Toshiaki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
2. SUGAWARA Akihiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
3. YAMADA Takeshi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SHIRAHATA Tatsuya 白畑 辰弥

Research Projects

Research Products

Co-Researchers

Study on synthetic sapnonins, candidates of vaccine adjuvant, via construction of glycosidic bond at C28 ester moiety by using microflow reactor.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel type of sequential glycosylation for creation of the synthetic vaccine.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Toward the Synthesis of Phomoidride D2013

Author(s)

Journal Title

Data Source

[Journal Article] Towar d the Synthesis of Phomoidr ide D2013

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetric total synthesis of neoxaline2013

Author(s)

Journal Title

Data Source

[Journal Article] Asymmetr ic Total Synthesis of Neoxaline2013

Author(s)

Journal Title

Data Source

[Journal Article] Petersson, George A.;?mura, Satoshi; Shiomi, Kazuro : Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventor s of ar bekacin resistance in MRSA2013

Author(s)

Journal Title

Data Source

[Journal Article] Aogacillins A and B produced by Simplicillium sp. FKI-5985: new circumventors of arbekacin resistance in MRSA2013

Author(s)

Journal Title

Data Source

[Journal Article] Oral adjuvant activity for nasal influenza vaccines causes by combination of nvo trihydroxy fatty acid stereoisomers from the tuber of Pinellia ternate2010

Author(s)

Journal Title

Data Source

[Journal Article] Improved catalytic and stereoselective glycosylation with glycosyl N-trichloroacetylcarbamate : application to various 1-hydroxy sugars2010

Author(s)

Journal Title

Data Source

[Journal Article] Improved catalytic and stereoselective glycosylation with glycosyl N-trichloroacetylcarbamate: application to various 1-hydroxy sugars2010

Author(s)

Journal Title

Data Source

[Journal Article] Oral adjuvant activity for nasal influenza vaccines causes by combination of two trihydroxy fatty acid stereoisomers from the tuber of Pinellia ternate2010

Author(s)

Journal Title

Data Source

[Presentation] 1-OH糖を使用した脱水的グリコシル化による三糖合成2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-In?uenza Virus Antibody Titer against Second Nasal Inoculation of In?uenza HA Vaccine of Oleanolic acid Sapnonins2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-In?uenza Virus Antibody Titer against Second Nasal Inoculation of In?uenza HA Vaccine of Oleanolic acid Sapnonins2013

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-Influenza Virus Antibody Titer against Second Nasal Inoculation of Influenza HA Vaccine of Oleanolic acid Sapnonins2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Synthesis and Effect of Nasal Administration on Nasal Anti-Influenza Virus Antibody Titer against Second Nasal Inoculation of Influenza HA Vaccine of Oleanolic acid Sapnonins2013

SHIRAHATA Tatsuya 白畑辰弥