Tsuda Hidetoshi 津田英利

… Alternative Names

津田英利ツダヒデトシ

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Researcher Number	30414923
Other IDs	https://orcid.org/0000-0002-1310-2319
Affiliation (Current)	2022: 自治医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020: 自治医科大学, 医学部, 助教 2018: 自治医科大学, 医学部, ポスト・ドクター 2017: 自治医科大学, 医学部, ポストドクター 2015 – 2016: 自治医科大学, 医学部, ポスト・ドクター 2013 – 2014: 自治医科大学, 医学部, ポストドクター
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator 乾癬 / ケラチノサイト / IL-33 / 細胞分裂 / siRNA / 細胞質分裂 / 細胞増殖 / 細胞周期 / 細胞収縮環 / 表皮角化細胞 … More / 転写調節機構 / 細胞内局在 / プロモーター / 細胞内動態 / 細部増殖 / 細胞局在 / Th17 / 乾癬モデルマウス / 細胞収縮管 / 細胞遊走能 / 皮膚科学 / PTRF/Cavin1 / Psoriasis / psoriasis / PTRF/Cavin-1 / 遺伝子機能解析 Less

Cellular function analysis of a novel psoriatic pathogenesis gene, PTRF / Cavin-1, and its involvement in psoriatic pathologyPrincipal Investigator
- Principal Investigator
  
  津田英利
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Jichi Medical University
Analysis of IL-33 function for cell division and proliferation in normal human epidermal keratinocytesPrincipal Investigator
- Principal Investigator
  
  Tduda Hidetoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Jichi Medical University
Functional analysis of IL-33 expressed in nucleus of normal human epidermal keratinocytePrincipal Investigator
- Principal Investigator
  
  Tsuda Hidetoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Jichi Medical University

All 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Differential expression of alarmins: IL-33 as a candidate marker for early diagnosis of toxic epidermal necrolysis2019
- Author(s)
  Adachi A., Komine M., Tsuda H., Nakajima S., Kabashima K., Ohtsuki M.
- Journal Title
  
  The Journal of Allergy and Clinical Immunology: In Practice
  
  Volume: 7 Pages: 325-327
- DOI
  10.1016/j.jaip.2018.05.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
[Journal Article] Generalized pustular psoriasis in a 92-year-old man with homozygous nonsense mutation in IL36RN.2018
- Author(s)
  Ueda Y, Komine M, Kamiya K, Tsuda H, Maekawa T, Murata S, Ohtsuki M
- Journal Title
  
  J Dermatol
  
  Volume: 45(3) Pages: 244-246
- DOI
  10.1111/1346-8138.14132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135
[Journal Article] Diagnosis of pseudoxanthoma elasticum in a 4-year-old boy.2018
- Author(s)
  Maki N., Komine M., Tsuda H., Fujita Y., Fujita E., Murata S., Demitsu T., Utani A., Ohtsuki M.
- Journal Title
  
  Journal of Dermatology
  
  Volume: 印刷中 Pages: 224226-224226
- DOI
  10.1111/1346-8138.13805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
[Journal Article] Interleukin-33 is expressed in the lesional epidermis in herpes virus infection but not in verruca vulgaris2018
- Author(s)
  Jin M., Komine M., Tsuda H., Oshio T., Ohtsuki M.
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 45 Pages: 855-857
- DOI
  10.1111/1346-8138.14334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
[Journal Article] Identification of the promoter region of human IL-33 responsive to induction by IFNγ.2017
- Author(s)
  Tsuda H., Komine M., Tominaga S., Ohtsuki M.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 85 Pages: 137140-137140
- DOI
  10.1016/j.jdermsci.2016.11.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
[Journal Article] Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice.2017
- Author(s)
  Oshio T., Komine M., Tsuda H., Tominaga S., Saito H., Nakae S., Ohtsuki M.
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 85 Pages: 106114-106114
- DOI
  10.1016/j.jdermsci.2016.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135, KAKENHI-PROJECT-16K10172
[Journal Article] Case of generalized pustular psoriasis exacerbated during pregnancy, successfully treated with infliximab2016
- Author(s)
  Adachi A., Komine M., Hirano T., Tsuda H., Karakawa M., Murata S., Ohtsuki M.
- Journal Title
  
  J Dertmatol
  
  Volume: 43 Pages: 1439-1440
- DOI
  10.1111/1346-8138.13429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10135
[Journal Article] Dual function of IL-33 on proliferation of NIH-3T3 cells.2015
- Author(s)
  Tominaga S., Tago K., Tsuda H., Komine M.
- Journal Title
  
  Cytokine.
  
  Volume: 72 Pages: 105-108
- DOI
  10.1016/j.cyto.2014.12.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461709, KAKENHI-PROJECT-26440062, KAKENHI-PROJECT-25460393
[Journal Article] Case of H syndrome with massive skin involvement, retroperitoneal fibrosis and Raynaud’s phenomenon with mutation in the SLC29A3 gene2015
- Author(s)
  Fujita E., Komine M., Tsuda H., Adachi A., Murata S., Kamata Y., Minota S., Ohtsuki M.
- Journal Title
  
  J Dermatol
  
  Volume: 42 Pages: 1-3
- DOI
  10.1111/1346-8138.12973
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461709
[Journal Article] CCL27 is downregulated by Interferon gannma via epidermal gorwth factor receptor in normal human epidermal keratinocyte2014
- Author(s)
  Karakawa M., Komine M., Hanakawa Y., Tsuda H., Sayama K., Tamaki K., Ohtsuki M.
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 229 Pages: 1935-1945
- DOI
  10.1002/jcp.24643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461709
[Journal Article] Expression of IL-33 in the epidermis: The mechanism of inductio by IL-172013
- Author(s)
  Meephansan J, Komine M, Tsuda H, Karakawa M, Tominaga S, Ohtsuki M.
- Journal Title
  
  Journal of Dermatological Sicence
  
  Volume: 71 Pages: 107114-107114
- DOI
  10.1016/j.jdermsci.2013.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591652, KAKENHI-PROJECT-25461709
[Presentation] TNFα suppressed IL-33 expression induced by STAT1 and STAT3 dependent signal2018
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Mamitaro Ohtsuki
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] TNFαは正常ヒト表皮角化細胞においてFli1の発現を誘導することによってIL-33の発現を抑制する2018
- Author(s)
  津田英利・小宮根真弓・大槻マミ太郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] 一時的な核内のIL-33の消失は表皮角化細胞の細胞分裂を抑制する2017
- Author(s)
  津田英利, 小宮根真弓, 大槻マミ太郎
- Organizer
  生命科学系学会合同年次大会　ConBio2017
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] Double-stranded RNA induces IL-33 promoter activation through TLR3-IRF3 pathway, depending on EGF receptor activation in normal human epidermal keratinocytes.2017
- Author(s)
  Jin, M., Komine, M., Tsuda, H., Tominaga, S., Ohtsuki, M
- Organizer
  76th Annual Meeting Society for Investigative Dermatology (SID)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] Expression of factors regulating cytokinesis in Bowen’s disease2017
- Author(s)
  Okada, H., Komine, M., Tsuda, H., Kamiya, K., Jin, M., Ohtsuki, M.
- Organizer
  The 47th Annual Meeting European Society for Dermatological Research (ESDR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] Nuclear IL-33 promotes wound healing by sustaining cell division and motility through regulating actin filament re-construction2017
- Author(s)
  Tsuda, H., Oshio, T., Komine, M., Tominaga, S., Ohtsuki, M.
- Organizer
  76th Annual Meeting Society for Investigative Dermatology (SID)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] STAT3 activation causes IL-33 expression in normal human epidermal keratinocyte2017
- Author(s)
  Tsuda, H., Komine, M., Ohtsuki, M.
- Organizer
  The 47th Annual Meeting European Society for Dermatological Research (ESDR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] Loss of IL-33 alters cytokine profile in imiquimod-induced psoriasis model2017
- Author(s)
  Tsuda, H., Komine, M., Nakae, S., Ohtsuki, M.
- Organizer
  The 42nd Annual Meeting of the Japanese Society for Investigative Dermatology (JSID)
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] IL-33 is essential in cell division of normal human epidermal keratinocytes in transient knock-down experiment2016
- Author(s)
  Tsuda H., Komine M., Jin M., Tominaga S., Ohtsuki M.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜、神奈川県、日本
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] Analysis of Oncostatin M signaling in hemangiosarcoma cell line and regulation of IL-33 expression2016
- Author(s)
  Tsuda H., Komine M., Jin M., Nakano N., Tominaga S., Masuzawa M., Ohtsuki M.
- Organizer
  第41回日本研究皮膚科学会学術大会
- Place of Presentation
  仙台国際センター、仙台、宮城県、日本
- Year and Date
  2016-12-09
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] The loss of nuclear IL-33 affects cell division of normal human keratinocyte2016
- Author(s)
  Tsuda H., Komine M., Tomninaga S., Ohtsuki M.
- Organizer
  第46回欧州研究皮膚科学会学術大会
- Place of Presentation
  Technical University of Munich, ミュンヘン, ドイツ
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PROJECT-16K10135
[Presentation] IL-33は正常ヒト表皮角化細胞内で細胞質分裂に関与している2015
- Author(s)
  津田英利・小宮根真弓・富永眞一・大槻マミ太郎
- Organizer
  第22回分子皮膚科学フォーラム
- Place of Presentation
  ホテル日航高知旭ロイヤル　高知
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] IL-33は表皮角化細胞核内で細胞分裂に関与している2015
- Author(s)
  津田英利・小宮根真弓・富永眞一・大槻マミ太郎
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド　神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Nuclear IL-33 is involved in cell proliferation via formation of contractile ring in normal human epidermal keratinocytes2015
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  Society of Investigative Dermatology 2015 Annual Meeting
- Place of Presentation
  HILTON ATLANTA, ATLANTA, GA, USA
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Oncostatin M induces IL-33 through STAT3 pathway in normal human epidermal keratinocytes2015
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  European Society for Dermatological Research
- Place of Presentation
  Postillion Convention Center-WTCロッテルダム　オランダ
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] IL-33 as a nuclear protein to affect proliferation and differentiation of normal human epidermal keratinocytes2013
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohshio, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] IL-33ノックダウンにより正常ヒト表皮角化細胞の細胞周期はG1/SからG2/M期へシフトする2013
- Author(s)
  津田英利・小宮根真弓・大塩智之・富永眞一・大槻マミ太郎
- Organizer
  第20回分子皮膚科学フォーラム
- Place of Presentation
  東京・浅草
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Knockdown of nuclear IL-33 suppressed proliferation of keratinocytes through inhibition of cytokinesis
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohsio, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  吹田、日本
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] 表皮各階細胞におけるIL-33発現調節機構の探索
- Author(s)
  津田英利、小宮根真弓、大塩智之、冨永眞一、大槻マミ太郎
- Organizer
  第21回分子皮膚科学フォーラム
- Place of Presentation
  京都、日本
- Year and Date
  2014-04-11 – 2014-04-12
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Regulation of IL-33 expression by normal human epidermal keratinocyte
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohsio, Shin-ich Tominaga, Mamitaro Ohtsuki
- Organizer
  44th Annual meeting of European Society for Dermatological Research
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2014-09-10 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Nuclear IL-33 regulates cell proliferation of keratinocyte via control of cytokinesis
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohsio, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜、日本
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25461709
[Presentation] Identification of the promoter region in human IL-33 gene, and analysis of its regulation in keratinocytes, endothelial cells and fibroblasts
- Author(s)
  Hidetoshi Tsuda, Mayumi Komine, Tomoyuki Ohshio, Shin-ichi Tominaga, Mamitaro Ohtsuki
- Organizer
  73rd Annual Meeting of Society for Investigative Dermatology
- Place of Presentation
  Albuquerque, USA
- Year and Date
  2014-05-07 – 2014-05-10
- Data Source
  KAKENHI-PROJECT-25461709

1. TAGO Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. Jin Meijuan

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 小宮根真弓

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
4. 富永眞一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsuda Hidetoshi 津田 英利

津田 英利 ツダ ヒデトシ

Research Projects

Research Products

Co-Researchers

Cellular function analysis of a novel psoriatic pathogenesis gene, PTRF / Cavin-1, and its involvement in psoriatic pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of IL-33 function for cell division and proliferation in normal human epidermal keratinocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of IL-33 expressed in nucleus of normal human epidermal keratinocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Differential expression of alarmins: IL-33 as a candidate marker for early diagnosis of toxic epidermal necrolysis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generalized pustular psoriasis in a 92-year-old man with homozygous nonsense mutation in IL36RN.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diagnosis of pseudoxanthoma elasticum in a 4-year-old boy.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Interleukin-33 is expressed in the lesional epidermis in herpes virus infection but not in verruca vulgaris2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of the promoter region of human IL-33 responsive to induction by IFNγ.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear expression of IL-33 in epidermal keratinocytes promotes wound healing in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Case of generalized pustular psoriasis exacerbated during pregnancy, successfully treated with infliximab2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual function of IL-33 on proliferation of NIH-3T3 cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Case of H syndrome with massive skin involvement, retroperitoneal fibrosis and Raynaud’s phenomenon with mutation in the SLC29A3 gene2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CCL27 is downregulated by Interferon gannma via epidermal gorwth factor receptor in normal human epidermal keratinocyte2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of IL-33 in the epidermis: The mechanism of inductio by IL-172013

Author(s)

Journal Title

DOI

Data Source

[Presentation] TNFα suppressed IL-33 expression induced by STAT1 and STAT3 dependent signal2018

Author(s)

Tsuda Hidetoshi 津田英利

津田英利ツダヒデトシ