Deguchi Tomonori 出口友則

… Alternative Names

出口友則デグチトモノリ

DEGUCHI Tomonori 出口友則

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Researcher Number	30415715
Other IDs	https://orcid.org/0000-0002-8842-1859
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2021: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2018 – 2019: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2017: 国立研究開発法人産業技術総合研究所, 生命工学領域バイオメディカル研究部門先端ゲノムデザイン研究グループ, 主任研究員 … More 2016: 国立研究開発法人産業技術総合研究所, 生命工学領域バイオメディカル研究部門, 主任研究員 2015: 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2014: 独立行政法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2013: 独立行政法人産業技術総合研究所, 健康工学研究部門, 研究グループ付 2012: 独立行政法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2010 – 2012: 独立行政法人産業技術総合研究所, 健康工学研究部門, 研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 90120:Biomaterials-related Except Principal Investigator Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Biological Sciences / Carcinogenesis
Keywords	Principal Investigator メダカ / リンパ管 / 発生 / マクロファージ / リンパ管新生 / TALEN / ゲノム編集 / ライブイメージング / 魚類 / Prox1 … More / トランスジェニック / 分子生物学 / In vivo imaging / 遺伝子組み換え / モデル動物 / 神経 … More Except Principal Investigator 癌 / 免疫細胞 / ナノメディシン / 再生医療 / 炭酸アパタイト / サイトカイン / 炎症老化 / 組織修復 / 慢性炎症 / 老化 / ナノ医薬 / 細胞・組織 / タンパク質 / 遺伝子 / バイオテクノロジー / メダカ / 発癌 / 病理学 Less

マクロファージ表現型制御によるリンパ管新生技術の開発Principal Investigator
- Principal Investigator
  
  出口友則
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Regenerative Therapy with Nanomedicine Capable of Reversing Chronic Inflammation into Tissue Repair Environment
- Principal Investigator
  
  戸井田力
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Cancer metastasis research that makes full use of innovative imaging technology and medaka as a model of cancer
- Principal Investigator
  
  Imamura Takeshi
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Ehime University
メダカの発生過程におけるリンパ管と神経の相互作用の解明Principal Investigator
- Principal Investigator
  
  出口友則
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
メダカの発生過程におけるリンパ管と神経の相互作用の解明Principal Investigator
- Principal Investigator
  
  出口友則
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of Laser-induced Tumor Model in Targeted Tissues
- Principal Investigator
  
  YUBA Shunsuke
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Carcinogenesis
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

[Journal Article] Application of Infrared Laser to the Zebrafish Vascular System: Gene Induction, Tracing, and Ablation of Single Endothelial Cells.2013
- Author(s)
  Kimura E, Deguchi T, Kamei Y, Shoji W, Yuba S, Hitomi J
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 33 Issue: 6 Pages: 1264-1270
- DOI
  10.1161/atvbaha.112.300602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590222, KAKENHI-PROJECT-23657109, KAKENHI-PROJECT-23659100, KAKENHI-PUBLICLY-25122721
[Journal Article] Transgenic medaka fish which mimic the endogenous expression of neuronal kinesin, KIF5A.2012
- Author(s)
  Kawasaki T, Kurauchi K, Higashihata A, Deguchi T, Ishikawa Y, Yamauchi M, Sasanuma M, Hori H, Tsutsumi M, Wakamatsu Y, Yuba S, Kinoshita M.
- Journal Title
  
  Brain Res.
  
  Volume: 1480 Pages: 12-21
- NAID
  120004874013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka.2012
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T., Maruyama, K., Yuba, S.
- Journal Title
  
  Genesis
  
  Volume: 50 Pages: 625-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka2012
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T.,Maruyama, K., Yuba, S
- Journal Title
  
  Genesis
  
  Volume: 50(8) Pages: 625-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] Intergenic region between TATA-box binding protein and proteasome subunit C3 genes of Medaka function as the bidirectional promoter in vitro and in vivo2012
- Author(s)
  Fujimori KE, Hazama K, Kawasaki T, Deguchi T, Yuba S
- Journal Title
  
  Gene.
  
  Volume: 511(2) Pages: 177-86
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka2012
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T., Maruyama, K., Yuba, S.
- Journal Title
  
  Genesis
  
  Volume: (印刷中) Issue: 8 Pages: 625-634
- DOI
  10.1002/dvg.22018
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23122522
[Journal Article] Intergenic region between TATA-box binding protein and proteasome subunit C3 genes of Medaka function as the bidirectional promoter in vitro and in vivo.2012
- Author(s)
  Fujimori KE, Hazama K, Kawasaki T, Deguchi T, Yuba S.
- Journal Title
  
  Gene
  
  Volume: 511 Pages: 177-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] Transgenic medaka fish which mimic the endogenous expression of neuronal kinesin, KIF5A2012
- Author(s)
  Kawasaki T, Kurauchi K, Higashihata A, Deguchi T, Ishikawa Y, Yamauchi M, Sasanuma M, Hori H, Tsutsumi M, Wakamatsu Y, Yuba S, Kinoshita M
- Journal Title
  
  Brain Res
  
  Volume: 1480 Pages: 12-21
- NAID
  120004874013
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] 魚類で辿るリンパ系の起源と発生2011
- Author(s)
  磯貝純夫、下田浩、出口友則、人見次郎、Brant M.Weinstein
- Journal Title
  
  リンパ学
  
  Volume: 34 Pages: 39-42
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23122522
[Journal Article] Identification of a functional Medaka heat shock promoter andcharacterization of its ability to induce in vitro and in vivoexogenous gene expression in Medaka2010
- Author(s)
  Oda, S., Mikami, S., Urushihara,Y., Murata, Y., Kamei, Y., Deguchi, T., Kitano, T., Fujimori, K.,Yuba, S., Todo, T., Mitani, H
- Journal Title
  
  Zoological Science
  
  Volume: 27(5) Pages: 410-5
- Data Source
  KAKENHI-PROJECT-22300322
[Journal Article] 赤外レーザーによる局所的遺伝子発現誘導法2010
- Author(s)
  浦和博子、出口友則、木村英二、伊藤真理子、鈴木基史、岡田清孝、八田公平、高木新、弓場俊輔、亀井保博
- Journal Title
  
  比較内分泌学
  
  Volume: 36(138) Pages: 217-21
- NAID
  10026666291
- Data Source
  KAKENHI-PROJECT-22300322
[Patent] リンパ管可視化トランスジェニックメダカ及び該メダカを用いたリンパ管新生阻害薬のスクリーニング法2012
- Inventor(s)
  出口友則・藤森一浩・川崎隆史・弓場俊輔
- Industrial Property Rights Holder
  独立行政法人産業技術総合研究所
- Acquisition Date
  2012-10-19
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Anatomy of lymphatic vasculature and peripheral nerves of medaka from the point of view of neurovascular interaction.2014
- Author(s)
  Tomonori Deguchi, Sumio Isogai, Hiroshi Shimoda, Takashi Kawasaki, Shunsuke Yuba
- Organizer
  the 18th International Vascular Biology Meeting
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] メダカの細胞を光らせて体ができる仕組みを知る2014
- Author(s)
  出口友則
- Organizer
  せっけん洗剤技術交流会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] メダカの発生過程におけるリンパ管と神経の相互作用の解明2013
- Author(s)
  出口友則、川﨑隆史、弓場俊輔
- Organizer
  第21回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] Distribution of proliferating cells around lesion during functional recovery after spinal injury in medaka fish.2013
- Author(s)
  川﨑隆史、出口友則、弓場俊輔
- Organizer
  日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] メダカの発生過程におけるリンパ管と神経の相互作用の解明2013
- Author(s)
  出口友則
- Organizer
  第10回水生動物の行動と神経系シンポジウム
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] メダカOryzias latipesのリンパ管発生2012
- Author(s)
  出口友則
- Organizer
  日本動物学会第83回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Interaction between lymphatic vasculature and peripheral nerves during development of medaka2012
- Author(s)
  出口友則
- Organizer
  Neuro-Vascular Wiring International Symposium 2012
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Interactionbetween lymphatic vasculature and peripheral nerves during development of medaka2012
- Author(s)
  Deguchi, T., Isogai, S., Shimoda, H.,Kawasaki, T., Yuba, S
- Organizer
  International Symposium 2012 Neuro-Vascular ring
- Place of Presentation
  Nara
- Year and Date
  2012-11-12
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Medaka is a new animal model to study lymphatic development and regeneration2012
- Author(s)
  Deguchi, T., Kawasaki, T., Yuba, S., Isogai, S., Shimoda, H., Nonaka, S., Hajiura-Kobayashi, H
- Organizer
  18th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  Kyoto
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] リンパ管の分子遺伝学的研究に役立つ新規実験モデル動物の確立～リンパ管再生医療技術開発へ向けて～2012
- Author(s)
  出口友則
- Organizer
  健康工学研究部門研究発表会
- Place of Presentation
  淡路島
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Medaka is a new animal model to study lymphatic development and regeneration2012
- Author(s)
  出口友則
- Organizer
  第18回小型魚類研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Application of infrared laser to the zebrafish vascular system: gene induction, tracing, and ablation of single endothelial cells2012
- Author(s)
  Kimura, E.,Deguchi, T., Kamei, Y., Shoji, W., Yuba, S., Hitomi, J
- Organizer
  第35回分子生物学会年会博多
- Place of Presentation
  博多
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Lymphatic Development of medaka, Oryzias latipes2012
- Author(s)
  Deguchi, T., Kawasaki, T., Yuba, S., Isogai, S., Shimoda, H., Nonaka, S.,Hajiura-Kobayashi, H
- Organizer
  日本動物学会第83回大会
- Place of Presentation
  大阪
- Year and Date
  2012-09-13
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] 組織可視化トランスジェニックメダカを用いたリンパ管形成機構の解明2011
- Author(s)
  出口友則
- Organizer
  日本リンパ学会第2回リンパ学に関する公本カンファランス
- Place of Presentation
  みやま荘、長野(招待講演)
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Generation of the transgenic medaka for in vivo imaging of cell-cycle2011
- Author(s)
  Deguchi, T., Matsumoto, T., Kawasaki, T., Yuba, S., Kinoshita, M., Sakaue-Sawano, A., Miyawaki, A., Naruse, K.
- Organizer
  第44回日本発生生物学会大会
- Place of Presentation
  沖縄コンベンションセンター、沖縄
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] Generation of the transgenic medaka for in vivo imaging of cell-cycle2011
- Author(s)
  Deguchi, T., Matsumoto, T., Kawasaki, T., Yuba, S., Kinoshita, M., Sakaue-Sawano, A., Miyawaki, A., Naruse, K.
- Organizer
  第44回日本発生生物学会大会
- Place of Presentation
  沖縄コンベンションセンター、沖縄
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Generation of the transgenic medaka for in vivo imaging of cell-cycle2011
- Author(s)
  Deguchi, T., Matsumoto, T., Kawasaki, T., Yuba, S.,Kinoshita, M., Sakaue-Sawano, A., Miyawaki, A., Naruse,K
- Organizer
  第44回日本発生生物学会大会
- Place of Presentation
  沖縄
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] The lymphatic vessels are visible in vivo in a pFLT4-EGFP transgenic medaka2011
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T., Maruyama, K., Yuba, S.
- Organizer
  The 1st Strategic Meeting for Medaka Research
- Place of Presentation
  Okazaki Conference Center, Aichi (Japan)
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] 胸管を形成するリンパ内皮細胞の由来とその前駆細胞を解剖学構造へと導くメカニズム2011
- Author(s)
  磯貝純夫、下田浩、出口友則、人見次郎、Brant M.Weinstein
- Organizer
  第35回日本リンパ学会総会
- Place of Presentation
  東京ステーションコンファレンス、東京
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PUBLICLY-23122522
[Presentation] The lymphatic vessels are visible in vivo in a pFLT4-EGFP transgenic medaka2011
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T., Maruyama, K., Yuba, S.
- Organizer
  The 1st Strategic Meeting for Medaka Research
- Place of Presentation
  Okazaki Conference Center, Aichi (Japan)
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] The lymphatic vessels are visible in vivo in a pFLT4-EGFP transgenicmedaka2011
- Author(s)
  Deguchi, T., Fujimori, KE., Kawasaki, T., Maruyama, K., Yuba,S
- Organizer
  The 1st Strategic Meeting for Medaka Research
- Place of Presentation
  Okazaki
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] pFLT4-EGFP トランスジェニックメダカを用いた in vivoでのリンパ管発生観察2010
- Author(s)
  Deguchi, T., Kawasaki,T., Isogai, S., Jiro, H., Yuba, S
- Organizer
  第43回日本発生生物学会大会
- Place of Presentation
  京都
- Year and Date
  2010-06-22
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Medaka is a new animal model to study lymphatic development and regeneration.
- Author(s)
  Deguchi, T., Kawasaki, T., Yuba, S., Isogai, S., Shimoda, H., Nonaka, S., Hajiura-Kobayashi, H.
- Organizer
  18th Japanese Medaka and Zebrafish Meeting
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Application of infrared laser to the zebrafish vascular system: gene inductio n, tracing, and ablation of single endothelial cells.
- Author(s)
  Kimura, E., Deguchi, T., Kamei, Y., Shoji, W., Yuba, S., Hitomi, J.
- Organizer
  第35回分子生物学会年会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Lymphatic Development of medaka, Oryzias latipes.
- Author(s)
  Deguchi, T., Kawasaki, T., Yuba, S., Isogai, S., Shimoda, H., Nonaka, S., Hajiura-Kobayashi, H.
- Organizer
  日本動物学会第83回大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Interaction between lymphatic vasculature and peripheral nerves during development of medaka.
- Author(s)
  Deguchi, T., Isogai, S., Shimoda, H., Kawasaki, T., Yuba, S.
- Organizer
  International Symposium 2012 Neuro-Vascular Wiring
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-22300322
[Presentation] Interaction between lymphatic vasculature and peripheral nerve during development of medaka
- Author(s)
  Tomonori Deguchi, Sumio Isogai, Hiroshi Shimoda, Takashi Kawasaki, Shunsuke Yuba
- Organizer
  第48回日本発生生物学会大会（ＡＰＤＢＮ共催）
- Place of Presentation
  つくば国際会議場（つくば）
- Year and Date
  2015-06-02 – 2015-06-05
- Data Source
  KAKENHI-PUBLICLY-25122721
[Presentation] Interaction between lymphatic vasculature and peripheral nerve during development of medaka
- Author(s)
  Tomonori Deguchi, Sumio Isogai, Hiroshi Shimoda, Takashi Kawasaki, Shunsuke Yuba
- Organizer
  International Symposium of Neurovascular Wiring 2015
- Place of Presentation
  関西セミナーハウス（京都）
- Year and Date
  2015-01-28 – 2015-01-29
- Data Source
  KAKENHI-PUBLICLY-25122721

1. 戸井田力 (40611554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YUBA Shunsuke (40263248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
3. KAWASAKI Takashi (60356839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
4. Imamura Takeshi (70264421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 川上良介 (40508818)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 齋藤卓 (60588705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 土谷享 (90722710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福田直志 (10804156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 人見次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 木村英二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Deguchi Tomonori 出口 友則

出口 友則 デグチ トモノリ

DEGUCHI Tomonori 出口 友則

Research Projects

Research Products

Co-Researchers

マクロファージ表現型制御によるリンパ管新生技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regenerative Therapy with Nanomedicine Capable of Reversing Chronic Inflammation into Tissue Repair Environment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cancer metastasis research that makes full use of innovative imaging technology and medaka as a model of cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メダカの発生過程におけるリンパ管と神経の相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メダカの発生過程におけるリンパ管と神経の相互作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Laser-induced Tumor Model in Targeted Tissues

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Application of Infrared Laser to the Zebrafish Vascular System: Gene Induction, Tracing, and Ablation of Single Endothelial Cells.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Transgenic medaka fish which mimic the endogenous expression of neuronal kinesin, KIF5A.2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka.2012

Author(s)

Journal Title

Data Source

[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka2012

Author(s)

Journal Title

Data Source

[Journal Article] Intergenic region between TATA-box binding protein and proteasome subunit C3 genes of Medaka function as the bidirectional promoter in vitro and in vivo2012

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[Journal Article] In vivo visualization of the lymphatic vessels in pFLT4-EGFP transgenic medaka2012

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DOI

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[Journal Article] Intergenic region between TATA-box binding protein and proteasome subunit C3 genes of Medaka function as the bidirectional promoter in vitro and in vivo.2012

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NAID

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Deguchi Tomonori 出口友則

出口友則デグチトモノリ

DEGUCHI Tomonori 出口友則