Fujita Yoshiko 藤田佳子

… Alternative Names

FUJITA YOSHIKO 藤田佳子

FUJITA Yoshiko 藤田佳子

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Researcher Number	30416218
Affiliation (based on the past Project Information) *help	2021: 信州大学, 医学部, 特任講師 2018 – 2019: 信州大学, 医学部, 特任講師 2017: 信州大学, 学術研究院医学系, 助教 2015: 信州大学, 学術研究院医学系, 助教 2013 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 研究員 … More 2010: 独立行政法人国立循環器病研究センター, 血管生理学部, 研究員 2009: National Cardiovascular Center Research Institute, 脈管生理部, 室員 2008: National Cardiovascular Center Research Institute, 脈管生理部, 室員 2008: National Cardiovascular Center Research Institute, 脈管生理部, 室員 2007: National Cardiovascular Center Research Institute, 研究所・脈管生理部, 室員 Less
Review Section/Research Field	Principal Investigator General pharmacology Except Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology
Keywords	Principal Investigator 血液 / 心血管 / 虚血性心疾患 / LOX-1 / 動脈硬化 / 受容体 / DAMPs / 血管 / 酸化LDL / 循環 … More Except Principal Investigator … More LOX-1 / 凝固因子 / DIC / 循環器・高血圧 / 複合体形成 / 変性LDL受容体 / クロストーク / GPCR Less

Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.
- Principal Investigator
  
  Sawamura Tatsuya
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Shinshu University
Elucidation of the relationships between pathogenic substances and DAMPs receptors.Principal Investigator
- Principal Investigator
  
  Fujita Yoshiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
Study of coagulation and thrombogenic system via the coagulation factor and the its new receptor.Principal Investigator
- Principal Investigator
  
  FUJITA YOSHIKO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General pharmacology
- Research Institution
  National Cardiovascular Center Research Institute
Elucidation of physiological significance of LOX-1 binding molecules
- Principal Investigator
  
  SAWAMURA Tatsuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
  National Cardiovascular Center Research Institute
Mechanism of vascular dysfunction induced by the interaction of CRP and LOX-1Principal Investigator
- Principal Investigator
  
  FUJITA Yoshiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  National Cardiovascular Center Research Institute
Mechanisms of vascular dysfunction induced by the interaction of vasoactive molecules.Principal Investigator
- Principal Investigator
  
  FUJITA Yoshiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  National Cardiovascular Center Research Institute

All 2016 2015 2014 2013 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Patent

[Journal Article] High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study2016
- Author(s)
  Yokota, C., Sawamura, T., Watanabe, M., Kokubo, Y., Fujita, Y., Kakino, A., Nakai, M., Toyoda, K., Miyamoto, Y. and Minematsu, K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 23 Issue: 10 Pages: 1222-1226
- DOI
  10.5551/jat.32466
- NAID
  130005598268
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-16K19192
[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015
- Author(s)
  Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T, Rakugi H.
- Journal Title
  
  FASEB J.
  
  Volume: ahead of print
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25893300
[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015
- Author(s)
  Yamamoto K, Kakino A, Takeshita H, Hayashi N, Li L, Nakano A, Hanasaki-Yamamoto H, Fujita Y, Imaizumi Y, Toyama-Yokoyama S, Nakama C, Kawai T, Takeda M, Hongyo K, Oguro R, Maekawa Y, Itoh N, Takami Y, Onishi M, Takeya Y, Sugimoto K, Kamide K, Nakagami H, Ohishi M, Kurtz TW, Sawamura T and Rakugi H.
- Journal Title
  
  The FASEB Journal
  
  Volume: Apr 15 Issue: 8 Pages: 3342-3356
- DOI
  10.1096/fj.15-271627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24601021, KAKENHI-PROJECT-15K01309, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25670133, KAKENHI-PROJECT-25293063
[Journal Article] Pitavastatin decreases serum LOX-1 ligand levels and MT1-MMP expression in CD14-positive mononuclear cells in hypercholesterolemic patients.2014
- Author(s)
  Uzui, H., Hayashi, H., Nakae, I., Matsumoto, T., Uenishi, H., Hayasaki, H., Asaji, T., Matsui, S., Miwa, K., Lee, J.D., Tada, H., Sawamura, T. and Fujita, M.
- Journal Title
  
  Int J Cardiol
  
  Volume: 176 Issue: 3 Pages: 1230-1232
- DOI
  10.1016/j.ijcard.2014.07.213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293063
[Journal Article] LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men.2013
- Author(s)
  Okamura T, Sekikawa A, Sawamura T, Kadowaki T, Barinas-Mitchell E, Mackey RH, Kadota A, Evans RW, Edmundowicz D, Higashiyama A, Nakamura Y, Abbott RD, Miura K, Fujiyoshi A, Fujita Y, Murakami Y, Miyamatsu N, Kakino A, Maegawa H, Murata K,　Horie M, Mitsunami K, Kashiwagi A, Kuller LH, Ueshima H
- Journal Title
  
  Atherosclerosis
  
  Volume: 229 Issue: 1 Pages: 240-245
- DOI
  10.1016/j.atherosclerosis.2013.04.023
- NAID
  130004782561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390178, KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25893300
[Journal Article] Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Plays an Important Role in Vascular Inflammation in Current Smokers2013
- Author(s)
  180. Takanabe-Mori, R., Ono, K., Wada, H., Takaya, T., Ura, S., Yamakage, H., Satoh-Asahara, N., Shimatsu, A., Takahashi, Y., Fujita, M., Fujita, Y., Sawamura, T. and Hasegawa, K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 20 Issue: 6 Pages: 585-590
- DOI
  10.5551/jat.16436
- NAID
  130004845439
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293063, KAKENHI-PROJECT-25893300
[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011
- Author(s)
  Nishizuka, T., Fujita, Y., Sato, Y., Nakano, A., Kakino, A., Ohshima, S., Kanda, T., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci
  
  Volume: 87(3) Pages: 104-113
- NAID
  130000669114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Procyanidins are potent inhibitors of LOX-1: a new player in the French Paradox2011
- Author(s)
  Nishizuka, T., Fujita, Y., Sato, Y., Nakano, A., Kakino, A., Ohshima, S., Kanda, T., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Proc Jpn Acad Ser B Phys Biol Sci 87(3)
  
  Pages: 104-113
- NAID
  130000669114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX-1 mediates vascular lipid retention under hypertensive state2010
- Author(s)
  Nakano, A., Inoue, N., Sato, Y., Nishimichi, N., Takikawa, K., Fujita, Y., Kakino, A., Otsui, K., Yamaguchi, S., Matsuda, H., Sawamura, T.
- Journal Title
  
  J Hypertens
  
  Volume: 28(6) Pages: 1273-1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX index, a novel predictive biochemical marker for coronary heart disease and stroke2010
- Author(s)
  Inoue, N., Okamura, T., Kokubo, Y., Fujita, Y., Sato, Y., Nakanishi, M., Yanagida, K., Kakino, A., Iwamoto, S., Watanabe, M., Ogura, S., Otsui, K., Matsuda, H., Uchida, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Clin Chem
  
  Volume: 56(4) Pages: 550-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX index, a novel predictive biochemical marker for coronary heart disease and stroke2010
- Author(s)
  Inoue, N., Okamura, T., Kokubo, Y., Fujita, Y., Sato, Y., Nakanishi, M., Yanagida, K., Kakino, A., Iwamoto, S., Watanabe, M., Ogura, S., Otsui, K., Matsuda, H., Uchida, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Clin Chem 56(4)
  
  Pages: 550-558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX-1-MT1-MMP axis is crucial for RhoA and Racl activation induced by oxidized low-density lipoprotein in endothelial cells2010
- Author(s)
  Sugimoto, K., Ishibashi, T., Sawamura, T., Inoue, N., Kamioka, M., Uekita, H., Ohkawara, H., Sakamoto, T., Sakamoto, N., Okamoto, Y., Takuwa, Y., Kakino, A., Fujita, Y., Tanaka, T., Teramoto, T., Maruyama, Y., Takeishi, Y.
- Journal Title
  
  Cardiovascular Research 84
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in failing rat hearts2010
- Author(s)
  Takaya, T., Wada, H., Morimoto, T., Sunagawa, Y., Kawamura, T., Takanabe-Mori, R., Shimatsu, A., Fujita, Y., Sato, Y., Fujita, M., Kimura, T., Sawamura, T., Hasegawa, K.
- Journal Title
  
  Circulation Journal 74
  
  Pages: 723-729
- NAID
  10026472482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 in failing rat hearts2010
- Author(s)
  Takaya, T., Wada, H., Morimoto, T., Sunagawa, Y., Kawamura, T., Takanabe-Mori, R., Shimatsu, A., Fujita, Y., Sato, Y., Fujita, M., Kimura, T., Sawamura, T., Hasegawa, K.
- Journal Title
  
  Circ J 74(4)
  
  Pages: 723-729
- NAID
  10026472482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] C-reactive protein uptake by macrophage cell line via class-A scavenger receptors2010
- Author(s)
  Fujita, Y., Kakino, A., Harada-Shiba, M., Sato, Y., Otsui, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Clinical Chemistry 56
  
  Pages: 478-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans2010
- Author(s)
  Matsumoto, T., Fujita, M., Sawamura, T., Kakino, A., Sato, Y., Fujita, Y., Matsuda, H., Nakanishi, M., Uchida, K., Nakae, I., Kanda, H., Yoshida, A., Miwa, K., Hayashi, H., Mitsunami, K., Horie, M.
- Journal Title
  
  Lipids 45(4)
  
  Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] C-reactive protein uptake by macrophage cell line via class-A scavenger receptor2010
- Author(s)
  Fujita, Y., Kakino, A., Harada-Shiba, M., Sato, Y., Otsui, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Clin Chem 56(3)
  
  Pages: 478-481
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX-1 mediates vascular lipid retention under hypertensive state2010
- Author(s)
  Nakano, A., Inoue, N., Sato, Y., Nishimichi, N., Takikawa, K., Fujita, Y., Kakino, A., Otsui, K., Yamaguchi, S., Matsuda, H., Sawamura, T.
- Journal Title
  
  J Hypertens 28(6)
  
  Pages: 1273-1280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Pitavastatin reduces lectin-like oxidized low-density lipoprotein receptor-1 ligands in hypercholesterolemic humans2010
- Author(s)
  Matsumoto, T., Fujita, M., Sawamura, T., Kakino, A., Sato, Y., Fujita, Y., Matsuda, H., Nakanishi, M., Uchida, K., Nakae, I., Kanda, H., Yoshida, A., Miwa, K., Hayashi, H., Mitsunami, K., Horie, M.
- Journal Title
  
  Lipids
  
  Volume: 45(4) Pages: 329-335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Oxidized LDL receptor LOX-12009
- Author(s)
  Fujita, Y., Sawamura, T.
- Journal Title
  
  Nippon Yakurigaku Zasshi 133
  
  Pages: 295-296
- NAID
  10025740803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Oxidized LDL receptor LOX-1 binds to C-reactive protein and mediates its vascular effects.2009
- Author(s)
  Fujita Y, Kakino A, Nishimichi N, Yamaguchi S, Sato Y, Machida S, Cominacini L, Delneste Y, Matsuda H, Sawamura T
- Journal Title
  
  Clinical Chemistry 55
  
  Pages: 285-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790200
[Journal Article] Lox-1 : the multifunctional receptor underlying cardiovascular dysfunction2009
- Author(s)
  Ogura, S., Kakino, A., Sato, Y., Fujita, Y., Iwamoto, S., Otsui, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Circ J 73(11)
  
  Pages: 1993-1999
- NAID
  10025936843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Oxidized LDL receptor LOX-1 binds to C-reactive protein and mediates its vascular effects.2009
- Author(s)
  Fujita Y, Kakino A, Nishimichi N, Yamaguchi S, Sato Y, Machida S, Cominacini L, Delneste Y, Matsuda H, Sawamura T.
- Journal Title
  
  Clinical Chemistry 55
  
  Pages: 285-294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790200
[Journal Article] Oxidized LDL receptor LOX-12009
- Author(s)
  Fujita, Y., Sawamura, T.
- Journal Title
  
  Nippon Yakurigaku Zasshi 133(5)
  
  Pages: 295-296
- NAID
  10025740803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] Lox-1: the multifunctional receptor underlying cardiovascular dysfunctions2009
- Author(s)
  Ogura, S., Kakino, A., Sato, Y., Fujita, Y., Iwamoto, S., Otsui, K., Yoshimoto, R., Sawamura, T.
- Journal Title
  
  Circulation Joumal 73
  
  Pages: 1993-1999
- NAID
  10025936843
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells2009
- Author(s)
  Sugimoto, K., Ishibashi, T., Sawamura, T., Inoue, N., Kamioka, M., Uekita, H., Ohkawara, H., Sakamoto, T., Sakamoto, N., Okamoto, Y., Takuwa, Y., Kakino, A., Fujita, Y., Tanaka, T., Teramoto, T., Maruyama, Y., Takeishi, Y.
- Journal Title
  
  Cardiovasc Res 84(1)
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790259
[Journal Article] LOX-1 abrogation reduces myocardial ischemia-reperfusion injury in mice.2008
- Author(s)
  Hu, C., Chen, J., Dandapat, A., Fujita, Y., Inoue, N., Kawase, Y., Jishage, K., Suzuki, H., Li, D., Hermonat, P. L., Sawamura, T., Mehta, J. L.
- Journal Title
  
  Journal of Molecular Cellular Cardiology 44
  
  Pages: 76-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790200
[Journal Article] LOX-1 deletion alters signals of myocardial remodeling immediately after ischemia-reperfusion.2007
- Author(s)
  Hu, C., Dandapat, A., Chen, J., Fujita, Y., Inoue, N., Kawase, Y., Jishage, K., Suzuki, H., Sawamura, T., Mehta, J. L.
- Journal Title
  
  Cardiovasc Research 76
  
  Pages: 292-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790200
[Journal Article] Big mitogen-activated protein kinase 1 (BMK1)/extracellular signal regulated kinase 5 (ERK5) is involved in platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell migration.2007
- Author(s)
  Izawa, Y., Yoshizumi, M., Ishizawa, K., Fujita, Y., Kondo, S., Kagami, S., Kawazoe, K., Tsuchiya, K., Tomita, S., Tamaki, T.
- Journal Title
  
  Hypertension Research 30
  
  Pages: 1107-1117
- NAID
  10021260102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790200
[Patent] 抗血液凝固剤2013
- Inventor(s)
  沢村達也、藤田佳子、垣野明美
- Industrial Property Rights Holder
  独立行政法人　国立循環器病研究センター
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-273308
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] PAF receptor interacts with LOX-1 and promotes oxidized LDL-induced cellular responses2015
- Author(s)
  Kakino, A., Fujita, Y., Yamamoto, K., Rakugi, H., Sawamura, T
- Organizer
  17th International Congress on Atherosclerosis 2015
- Place of Presentation
  Amsterdam (Holland)
- Year and Date
  2015-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達を促進する2015
- Author(s)
  垣野明美、山本浩一、藤田佳子、楽木宏美、沢村達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都府京都市、ハイアットリージェンシー京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 脳出血とアテローム血栓性脳梗塞における可溶性Lectin-like oxidized LDL receptor-1高値：症例・対照研究2015
- Author(s)
  横田千晶、沢村達也、渡邊至、小久保喜弘、藤田佳子、垣野明美、中井陸運、豊田一則、宮本恵宏、峰松一夫
- Organizer
  第27回日本脳循環代謝学会総会
- Place of Presentation
  富山県富山市、富山国際会議場
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] LOX-1 遺伝子欠損SHRSPの作製とその形質の予備的解析2014
- Author(s)
  垣野明美、李　蕾、池末昌弘、中野厚史、藤田佳子、岡澤　慎、真下知士、沢村達也
- Organizer
  第50回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  和歌山県立医科大学生涯研修センター、和歌山
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1 directly interacting with LOX-1 mediates signal transduction induced by oxidized LDL.2014
- Author(s)
  A. Kakino, K.Yamamoto, A.Nakano, L.Li, Y. Fujita, H.Rakugi, T.Sawamura
- Organizer
  The 82nd Congress of the European Atherosclerosis Society (EAS 2014)
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-06-01
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Overexpression of Del-1, An oxidized LDL blocking protein, suppressed atherogenesis in mice without lowering oxidized LDL concentration, but with reducing LOX-1 ligand containing apoB activity (LAB).2014
- Author(s)
  Akemi. Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura.
- Organizer
  American Association for Clinical Chemistry Annual Meeting and Clinical Lab Expo
- Place of Presentation
  Chicago, U.S.A.
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Del-1は酸化LDL－受容体相互作用を阻害し、血管壁脂質沈着を抑制する Del-1 as an endogenous blocker of oxidized LDL which suppresses arterial lipid accumulation2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第17回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Identification of Endogenous Anti-Atherogenic Protein Which Blocks the Interaction between Oxidized LDL and Its Receptors2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  AHA Scientific Sessions 2013
- Place of Presentation
  アメリカ・ダラス
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] An endogenous blocker of oxidized LDL2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  13th International Conference on Endothelin (ET-13)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] 内因性蛋白質による新しい酸化LDL作用阻害機構 Inhibition of oxidized LDL action by an endogenous protein2013
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1はLOX-1を介した酸化LDLによるシグナル伝達と血管壁脂質沈着を促進する2013
- Author(s)
  垣野明美、山本浩一、中野厚史、李蕾、藤田佳子、楽木宏実、沢村達也
- Organizer
  第49回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Regulation Of Cellular Lipid Metabolism In Atherogenesis2013
- Author(s)
  Akemi Kakino, Atsushi Nakano, Yoshiko Fujita, Tatsuya Sawamura
- Organizer
  The 81st Congress of the European Atherosclerosis Society (EAS 2013)
- Place of Presentation
  フランス・リヨン
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] プロシアニジンはLOX-1アンタゴニストであり、血管壁への脂質沈着を抑制する2011
- Author(s)
  善本亮、西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、沢村達也
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  (誌上開催)
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] プロシアニジンはLOX-1アンタゴニストであり、血管壁への脂質沈着を抑制する2011
- Author(s)
  善本亮、西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、沢村達也
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  誌上開催
- Year and Date
  2011-03-23
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] プロシアニジンは酸化LDL受容体LOX-1のアンタゴニストであり、ラット血管壁への脂質沈着を抑制する2010
- Author(s)
  西塚太一、藤田佳子、佐藤優子、中野厚史、垣野明美、大嶋俊二、神田智正、善本亮、沢村達也
- Organizer
  第20回日本循環薬理学会
- Place of Presentation
  札幌
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] LOX-1 is involved in the complement activation by endogenous C-reactive protein and myocardial reperfusion injury2010
- Author(s)
  藤田佳子、乙井一典、垣野明美、山口三郎、佐藤優子、善本亮、沢村達也
- Organizer
  15th World Cogress on Heart Disease
- Place of Presentation
  バンクーバー
- Year and Date
  2010-07-25
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] Recognition of endogenous C-reactive protein by LOX-1 abrogates myocardial infarction2010
- Author(s)
  藤田佳子、乙井一典、垣野明美、山口三郎、佐藤優子、善本亮、沢村達也
- Organizer
  ISHR (World Congress of the International Society for Heart Research)
- Place of Presentation
  京都
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] 酸化LDL測定のための人工標準蛋白作製2010
- Author(s)
  岩元真、藤田佳子、垣野明美、柳田一樹、善本亮、沢村達也
- Organizer
  第83回日本生化学会大会、第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] C-REACTIVE PROTEIN BINDS TO LOX-1 AND CAUSES VASCULAR DYSFUNCTION VIA COMPLEMENT ACTIVATION2010
- Author(s)
  藤田佳子、乙井一典、垣野明美、山口三郎、佐藤優子、善本亮、沢村達也
- Organizer
  International SHR Symposium
- Place of Presentation
  モントリオール
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] CRPはSR-Aを介してマクロファージに取り込まれる2010
- Author(s)
  藤田佳子、垣野明美、佐藤優子、善本亮、沢村達也
- Organizer
  第83回日本薬理学会
- Place of Presentation
  大阪(大阪国際会議場)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] The effect of LOX-1 and LOX-1 ligand containing ApoB on the incidence of coronary heart disease and stroke in an 11-year population-based cohort study : The Suita study2010
- Author(s)
  Okamura, T., Inoue, N., Kokubo, Y., Fujita, Y., Sato, Y., Watanabe, M., Sawamura, T.
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] CRPはSR-Aを介してマクロファージに取り込まれる2010
- Author(s)
  藤田佳子、垣野明美、佐藤優子、善本亮、沢村達也
- Organizer
  第83回薬理学会年会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] The effect of LOX-1 and LOX-1 ligands containing ApoB on the incidence of coronary heart disease and stroke in an 11-year population-based cohort study : The Suita study2010
- Author(s)
  Okamura, T., Inoue, N., Kokubo, Y., Fujita, Y., Sato, Y., Watanabe, M., Sawamura, T.
- Organizer
  第42回日本動脈硬化学会
- Place of Presentation
  岐阜
- Year and Date
  2010-07-16
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] LOX-1 is involved in the complement activation by endogenous C-reactive protein and myocardial reperfusion injury2010
- Author(s)
  藤田佳子、乙井一典、垣野明美、山口三郎、佐藤優子、善本亮、沢村達也
- Organizer
  15th World Congress on Heart Disease
- Place of Presentation
  バンクーバー
- Year and Date
  2010-07-25
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] LOX-1はC反応蛋白を結合し、その血管に対する反応を媒介する2009
- Author(s)
  藤田佳子
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  神奈川パシフィコ横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19790200
[Presentation] CRPによる心筋梗塞悪化へのLOX-1の関与2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、沢村達也
- Organizer
  日本心血管内分泌代謝学会
- Place of Presentation
  大宮
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] LOX-1 BINDS TO C-REACTIVE PROTEIN AND MEDIATES ITS EFFECTS ON CARDIOVASCULAR SYSTEM2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、西道教尚、松田治男、沢村達也
- Organizer
  XV International Symposium on Atherosclerosis
- Place of Presentation
  Boston, MA, USA (John B.Hynes Veterans Memorial Convention Center)
- Year and Date
  2009-06-16
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] CRPはLOX-1依存性に補体系を活性化し、心筋梗塞を悪化させる2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、沢村達也
- Organizer
  高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] 酸化LDL受容体LOX-1はCRPと協調して血管機能変化・心筋梗塞巣拡大を引き起こす2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、小倉紗世子、岩元真、沢村達也
- Organizer
  第7回メタボリックシンドローム研究会
- Place of Presentation
  京都
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] LOX-1はC反応蛋白を結合し、その血管に対する反応を媒介する2009
- Author(s)
  藤田佳子、垣野明美、西道教尚、山口三郎、佐藤優子、松田治男、沢村達也
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  神奈川(パシフィコ横浜)
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19790200
[Presentation] LOX-1 BINDS TO C-REACTIVE PROTEIN AND MEDIATES ITS EFFECTS ON CARDIOVASCULAR SYSTEM2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、西道教尚、山口三郎、松田治男、沢村達也
- Organizer
  国際動脈硬化学会
- Place of Presentation
  ボストン
- Year and Date
  2009-06-17
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] 酸化LDL受容体LOX-1はCRPと協調して血管機能変化・心筋梗塞巣拡大を引き起こす2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、小倉彩世子、岩元真、沢村達也
- Organizer
  第7回メタボリックシンドローム研究会
- Place of Presentation
  京都(ホテルグランヴィア京都)
- Year and Date
  2009-07-18
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] CRPによる心筋梗塞悪化へのLOX-1の関与2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、沢村達也
- Organizer
  第13回日本心血管内分泌代謝学会
- Place of Presentation
  埼玉(大宮ソニックシティ)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] HSP90は細胞膜受容体を介して血管新生を促進する2009
- Author(s)
  佐藤優子、藤田佳子、垣野明美、小倉彩世子、岩元真、善本亮、沢村達也
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都(京都大学)
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] CRPはLOX-1依存性に補体系を活性化し、心筋梗塞を悪化させる2009
- Author(s)
  藤田佳子、垣野明美、乙井一典、山口三郎、佐藤優子、沢村達也
- Organizer
  第45回高血圧関連疾患モデル学会学術総会
- Place of Presentation
  東京(東京ステーションコンフアレンス)
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] HSP90は細胞膜受容体を介して血管新生を促進する2009
- Author(s)
  佐藤優子、藤田佳子、垣野明美、小倉紗世子、岩元真、善本亮、沢村達也
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21790259
[Presentation] C-reactive protein(CRP)は酸化LDL受容体LOX-1と協調して補体活性化を引き起こす2008
- Author(s)
  藤田佳子
- Organizer
  第18回日本循環薬理学会
- Place of Presentation
  千葉京成ホテルミラマーレ
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19790200
[Presentation] C-reactive protein (CRP)は酸化LDL受容体LOX-1と協調して補体活性化を引き起こす2008
- Author(s)
  藤田佳子、垣野明美、山口三郎、沢村達也
- Organizer
  第18回日本循環薬理学会
- Place of Presentation
  千葉(京成ホテルミラマーレ)
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-19790200
[Presentation] 酸化LDL阻害分子Del-1の過剰発現は、マウス血管壁脂質沈着を抑制する
- Author(s)
  垣野明美、中野厚史、藤田佳子、沢村達也
- Organizer
  第23回日本循環薬理学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] AT1 promotes oxLDL-induced cell responses through interact with LOX-1.
- Author(s)
  Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
- Organizer
  第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場、神戸
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25293063
[Presentation] Interaction between AT1 and LOX-1 promote oxLDL-induced cell responses.
- Author(s)
  Akemi Kakino, Koichi Yamamoto, Lei Li, Yoshiko Fujita, Hiromi Rakugi, Tatsuya Sawamura
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場、名古屋
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25293063

1. SAWAMURA Tatsuya (30243033)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. KAKINO Akemi (00534637)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. 堀内清香 (20789820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HIGASHIYAMA Aya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 岡村智教

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 上島弘嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 三浦克之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中野厚史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fujita Yoshiko 藤田 佳子

FUJITA YOSHIKO 藤田 佳子

FUJITA Yoshiko 藤田 佳子

Research Projects

Research Products

Co-Researchers

Elucidation of the significance of LOX-1 and endothelial dysfunction as the pathological basis of disseminated intravascular coagulation.

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Elucidation of the relationships between pathogenic substances and DAMPs receptors.Principal Investigator

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Study of coagulation and thrombogenic system via the coagulation factor and the its new receptor.Principal Investigator

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Elucidation of physiological significance of LOX-1 binding molecules

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Mechanism of vascular dysfunction induced by the interaction of CRP and LOX-1Principal Investigator

Principal Investigator

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Mechanisms of vascular dysfunction induced by the interaction of vasoactive molecules.Principal Investigator

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[Journal Article] High Levels of Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Acute Stroke: An Age- and Sex-Matched Cross-Sectional Study2016

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[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015

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[Journal Article] Oxidized LDL (oxLDL) activates the angiotensin II type 1 receptor by binding to the lectin-like oxLDL receptor.2015

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[Journal Article] Pitavastatin decreases serum LOX-1 ligand levels and MT1-MMP expression in CD14-positive mononuclear cells in hypercholesterolemic patients.2014

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[Journal Article] LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men.2013

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[Journal Article] Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Plays an Important Role in Vascular Inflammation in Current Smokers2013

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[Journal Article] Procyanidins are potent inhibitors of LOX-1 : a new player in the French Paradox2011

Author(s)

Fujita Yoshiko 藤田佳子

FUJITA YOSHIKO 藤田佳子

FUJITA Yoshiko 藤田佳子