DOI Hikaru 土井光

… Alternative Names

土井光ドイヒカル

Less

Researcher Number	30423552
Affiliation (based on the past Project Information) *help	2010: 九州大学, 大学病院, 助教 2009: Kyushu University, 大学病院, 医員 2008 – 2009: Kyushu University, 大学病院, 特任助教 2006: 九大, 大学病院
Review Section/Research Field	Principal Investigator Neurology Except Principal Investigator Neurology
Keywords	Principal Investigator アクアポリン4 / 視神経脊髄炎 / 多発性硬化症 / 抗アクアポリン4抗体 Except Principal Investigator 自己抗体 / 膜蛋白質 / マイクロアレイ / CIDP / IL7RA / バイオマーカー … More / 自己抗体プロファイル / IL2RA / HLA / 視神経脊髄炎 / サイトカイン / 遺伝子間相互作用 / 多発性硬化症 / Caspr / ギラン・バレー症候群 / Naチャンネル / 軸索傷害 / Dps / Campylobacter jejuni / ギランバレー症候群 Less

Development of molecular targeted therapy of multiple sclerosis on the basis of membrane protein microarray analysis and gene interactions
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
CIDPにおける膜蛋白質を標的としたantigen　microarray解析
- Principal Investigator
  
  川尻真和
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
軸索型ギラン・バレー症候群先行感染菌由来蛋白の軸索膜ポア形成による傷害とその治療
- Principal Investigator
  
  KIRA Jun-ichi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
Analysis of new antigen in anti aquaporin-4 antibody-negative neuromyelitis opticaPrincipal Investigator
- Principal Investigator
  
  DOI Hikaru
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University
機能的MRIによる脊髄小脳変性症の病態解析Principal Investigator
- Principal Investigator
  
  土井光
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University

All 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 神経救急-見落とされがちな神経疾患を中心にE.中枢神経系の救急22.多発性硬化症2009
- Author(s)
  土井光, 吉良潤一
- Total Pages
  3
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20790618
[Book] Clinical Neuroscience 2009(神経救急-見落とされがちな神経疾患を中心に E. 中枢神経系の救急 22. 多発性硬化症, 27巻8号)2009
- Author(s)
  土井光, 吉良潤一
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Analysis of cerebrospinal fluid cytokines and growth factors in multiple sclerosis patients with and without chronic headaches2011
- Author(s)
  DoiH,MatsushitaT,IsobeN,TateishiT,KiraJ
- Journal Title
  
  Neurology Asia
  
  Volume: 16 Pages: 65-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178
[Journal Article] Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians2011
- Author(s)
  Fang L*, Isobe N*, Yoshimura S, Yonekawa T, Matsushita T, Masaki K, Doi H, Ochi K, Miyamoto K, Kawano Y, Kira J
- Journal Title
  
  Neurology
  
  Volume: 76 Issue: 24 Pages: 2125-2127
- DOI
  10.1212/wnl.0b013e31821f466c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178
[Journal Article] Reappraisal of brain MRI features in multiple sclerosis and neuromyelitis optica patients according to anti-aquaporin-4 antibody status2010
- Author(s)
  Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, Masaki K, Yoshimura T, Yamasaki R, Ohyagi Y, Kira J
- Journal Title
  
  J Neurol Sci
  
  Volume: 291 Issue: 1-2 Pages: 37-43
- DOI
  10.1016/j.jns.2010.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390178
[Journal Article] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitisoptica according to anti-aquaporin-4 antibody status2010
- Author(s)
  Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, et al
- Journal Title
  
  Journal of the Neurological Sciences 291
  
  Pages: 37-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitis optica according to anti-aquaporin-4 antibody status2010
- Author(s)
  Matsushita T, Isobe N, Piao H, Matsuoka T, Ishizu T, Doi H, Masaki K, Yoshiura T, Yamasaki R, Ohyagi Y, Kira J
- Journal Title
  
  J Neurol Sci. 291
  
  Pages: 37-43
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and -negative multiple sclerosis patients2009
- Author(s)
  Watanabe A, Matsushita T, Doi H, Matsuoka T, Shigeto H, Isobe N, Kawano Y, Tobimatsu S, Kira J
- Journal Title
  
  J Neurol Sci 281
  
  Pages: 34-40
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin4 antibody2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Journal Title
  
  Mult Scler 15
  
  Pages: 304-310
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody.2009
- Author(s)
  Doi H, Matsushita T, Isobe N, et al
- Journal Title
  
  Multiple Sclerosis 15
  
  Pages: 304-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009
- Author(s)
  Doi H, et al.
- Journal Title
  
  Multipl Scler 15
  
  Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659141
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody.2009
- Author(s)
  Doi H, et al
- Journal Title
  
  Mult Scler 15
  
  Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659141
[Journal Article] Frequency of chronic headaches in Japanese patients with multiple sclerosis.2009
- Author(s)
  Doi H, Matsushita T, Isobe N, et al
- Journal Title
  
  Headache 49
  
  Pages: 1513-1520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Frequency of chronic headaches in Japanese patients with multiple sclerosis.2009
- Author(s)
  Doi H, Matsushita T, Isobe N, Ishizu T, Ohyagi Y, Kira J
- Journal Title
  
  Headache 49
  
  Pages: 1513-1520
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Frequency of chronic headaches in Japanese patients with multiple sclerosis2009
- Author(s)
  Doi H, Matsushita T, Isobe N, et.al.
- Journal Title
  
  Headache (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 anti body2009
- Author(s)
  Doi H, Matsushita T, Isobe N, et.al.
- Journal Title
  
  Multiple Sclerosis 15
  
  Pages: 304-310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Frequency of chronic headaches inJapanese patients with multiple sclerosis with special referency to opticospinal and common forms of multiple sclerosis.2009
- Author(s)
  Doi H, et al
- Journal Title
  
  Headaache (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659141
[Journal Article] Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and -negative multiple sclerosis patients.2009
- Author(s)
  Watanabe A, Matsushita T, Doi H, et al
- Journal Title
  
  Jouranal of the Neurological Sciences 281
  
  Pages: 34-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Frequency of chronic headaches in Japanese patients with multiple sclerosin : with special reference to opticospinal and common forms of multiple sclerosis2009
- Author(s)
  Doi H, et al.
- Journal Title
  
  Headache 49
  
  Pages: 1513-1520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659141
[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin4 antibody2008
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Journal Title
  
  Neurology Asia 13
  
  Pages: 227-229
- Data Source
  KAKENHI-PROJECT-20790618
[Journal Article] Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and -nesative multiple sclerosis patients
- Author(s)
  Watanabe A, Matsushita T, Doi H, et.al.
- Journal Title
  
  Jouranal of the Neurological Sciences (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] Interferon-beta reduces peripheral blood IFN-γ and IL-17-producing T cells in patients with multiple sclerosis.2012
- Author(s)
  Song ZY、Doi H、Yoshimura S、Tateishi T、Yonekawa T、Matsushita T、Kira J
- Organizer
  PACTRIMS
- Place of Presentation
  北京
- Data Source
  KAKENHI-PROJECT-22390178
[Presentation] 多発性硬化症患者へのインターフェロンβ導入による脳脊髄液中サイトカインの影響2010
- Author(s)
  土井光, ら
- Organizer
  日本神経免疫学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 多発性硬化症患者へのインターフェロンβ導入による脳脊髄液中サイトカインへの影響2010
- Author(s)
  土井光, 松下拓也, 立石貴久, 磯部紀子, 吉良潤一
- Organizer
  第22回日本神経免疫学会総会
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 抗アクアポリン4抗体陽性症例の再発期における高補体血症の存在2009
- Author(s)
  土井光, 松下拓也, 磯部紀子, 松岡健, 三野原元澄, 越智博文, 吉良潤一
- Organizer
  第50回日本神経学会総会
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 慢性頭痛を伴う多発性硬化症患者の脳脊髄液中サイトカイン分析2009
- Author(s)
  土井光, 松下拓也, 立石貴久, 磯部紀子, 大八木保政, 吉良潤一
- Organizer
  第37回日本頭痛学会総会
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 多発性硬化症および高アクアポリン4抗体陽性症例における補体系の検討2009
- Author(s)
  土井光, 松下拓也, 磯部紀子, 松岡健, 三野原元澄, 越智博文, 吉良潤一
- Organizer
  第21回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 多発性硬化症および抗アクアポリン4抗体陽性症例における補体系の検討2009
- Author(s)
  土井光ら
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 抗アクアポリン4抗体陽性症例の再発期における高補体血症2009
- Author(s)
  土井光, ら
- Organizer
  日本神経学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 多発性硬化症および抗アクアポリン4抗体陽性症例における補体系の検討2009
- Author(s)
  土井光, ら
- Organizer
  第21回日本神経免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] Hypercomplementemia at Relapse in Patients with Anti-Aquaporin-4 Antibody2008
- Author(s)
  Doi H, et al
- Organizer
  PACTRIMS for Treatment and Research in Multiple Sclerosis
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-20659141
[Presentation] 多発性硬化症における慢性頭痛の羅患率およびその病態の検討2008
- Author(s)
  土井光, ら
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 日本人多発性硬化症患者における慢性頭痛罹患率の検討2008
- Author(s)
  土井光, 松下拓也, 松岡健, 三野原元澄, 吉良潤一
- Organizer
  第36回日本頭痛学会総会
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 多発性硬化症における慢性頭痛の罹患率およびその病態の検討2008
- Author(s)
  土井光, 松岡健松, 下拓也, 越智博文, 三野原元澄, 大八木保政, 吉良潤一
- Organizer
  第49回日本神経学会総会
- Year and Date
  2008-05-15
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2008
- Author(s)
  Doi H, Matsushita T, Isobe N, Matsuoka T, Minohara M, Ochi H, Kira J
- Organizer
  First congress of the Pan-Asian committee for treatment and research in multiple sclerosis
- Place of Presentation
  Kuala Lumpur, Malaysia
- Data Source
  KAKENHI-PROJECT-20790618
[Presentation] 日本人多発性硬化症患者における慢性頭痛罹患率の検討2008
- Author(s)
  土井光, ら
- Organizer
  第36回日本頭痛学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790618

1. KAWAMURA Nobutoshi (00432930)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KIRA Jun-ichi (40183305)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. MATSUSHITA Takuya (00533001)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 三野原元澄 (70398113)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KAWANO Yuji (20333479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YOSHIMURA Satoshi (20596390)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 川尻真和 (00335960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

DOI Hikaru 土井 光

土井 光 ドイ ヒカル

Research Projects

Research Products

Co-Researchers

Development of molecular targeted therapy of multiple sclerosis on the basis of membrane protein microarray analysis and gene interactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

CIDPにおける膜蛋白質を標的としたantigen microarray解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

軸索型ギラン・バレー症候群先行感染菌由来蛋白の軸索膜ポア形成による傷害とその治療

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of new antigen in anti aquaporin-4 antibody-negative neuromyelitis opticaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

機能的MRIによる脊髄小脳変性症の病態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 神経救急-見落とされがちな神経疾患を中心にE.中枢神経系の救急22.多発性硬化症2009

Author(s)

Total Pages

Publisher

Data Source

[Book] Clinical Neuroscience 2009(神経救急-見落とされがちな神経疾患を中心に E. 中枢神経系の救急 22. 多発性硬化症, 27巻8号)2009

Author(s)

Data Source

[Journal Article] Analysis of cerebrospinal fluid cytokines and growth factors in multiple sclerosis patients with and without chronic headaches2011

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-7 receptor alpha gene polymorphism influences multiple sclerosis risk in Asians2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reappraisal of brain MRI features in multiple sclerosis and neuromyelitis optica patients according to anti-aquaporin-4 antibody status2010

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitisoptica according to anti-aquaporin-4 antibody status2010

Author(s)

Journal Title

Data Source

[Journal Article] Reappraisal of brain MRI features in patients with multiple sclerosis and neuromyelitis optica according to anti-aquaporin-4 antibody status2010

Author(s)

Journal Title

Data Source

[Journal Article] Multimodality evoked potential study of anti-aquaporin-4 antibody-positive and -negative multiple sclerosis patients2009

Author(s)

Journal Title

Data Source

[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin4 antibody2009

Author(s)

Journal Title

Data Source

[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody.2009

Author(s)

Journal Title

Data Source

[Journal Article] Hypercomplementemia at relapse in patients with anti-aquaporin-4 antibody2009

Author(s)

Journal Title

DOI Hikaru 土井光

土井光ドイヒカル

CIDPにおける膜蛋白質を標的としたantigen　microarray解析