KAWAJI Takahiro 川路隆博

Researcher Number	30423677
Other IDs
Affiliation (based on the past Project Information) *help	2010 – 2016: 熊本大学, 医学部附属病院, 講師 2008: 熊本大学, 医学部附属病院, 講師 2007: Kumamoto University, University Hospital, Research associate 2006: 熊本大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Ophthalmology Except Principal Investigator Ophthalmology
Keywords	Principal Investigator 家族性アミロイドポリニューロパチー / 緑内障 / トランスサイレチン / 網膜色素上皮 / 移植 / 再生医療 / 外科 / 形質転換 / 移植・再生医療 / トラベクレクトミー … More / 国際情報交流 / アミロイド / 濾過手術 / 続発緑内障 / 硝子体混濁 … More Except Principal Investigator 緑内障 / サイトカイン / 生理活性 / 眼薬理学 / 創傷治癒 / 房水 / MCP-1 / 線維柱体 / シュレム管 / 網膜色素上皮 / 上皮間葉転換 / 加齢黄斑変性 / シグナル伝達 / 生体分子 / 房水流出路 / ROCK阻害薬 / トリアムシノロン / アミロイドーシス / 薬理学 / 臨床 / glaucoma / aqueous humor outflow pathway / ROCK inhibitor / triamcinolone acetonide / amyloidosis Less

The regulation of bioactive molecule dynamics and development of real-time imaging technics for glaucoma therapy.
- Principal Investigator
  
  Tanihara Hidenobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
家族性眼アミロイドーシスの早期発見と手術合併症の克服に関する研究Principal Investigator
- Principal Investigator
  
  川路隆博
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
Research of epithelial-to-mesenchymal transition via redox regulation for age related macular degeneration
- Principal Investigator
  
  Inomata Yasuya
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
The effects of aqueous bioactive molecules on aqueous outflow dynamics and filtration-surgery results
- Principal Investigator
  
  TANIHARA Hidenobu
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
The investigation for pathogenesis of glaucoma and the overcome of complications of filtering surgery via focusing on transthyretinPrincipal Investigator
- Principal Investigator
  
  KAWAJI Takahiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
New therapeutic approach for glaucoma via drug-mediated bleb regulation
- Principal Investigator
  
  TANIHARA Hidenobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
初代網膜色素上皮培養細胞における形質転換および移植手術に関する研究Principal Investigator
- Principal Investigator
  
  川路隆博
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University
The investigation for molecular mechanisms of aqueous humor outflow and the creation of new treatments for intraocular pressure elevation in glaucomatous eyes
- Principal Investigator
  
  TANIHARA Hidenobu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kumamoto University

All 2016 2014 2013 2012 2011 2009 2006 Other

All Journal Article Presentation

[Journal Article] Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity.2016
- Author(s)
  T. Tsutsumi, K. Iwao, H. Hayashi, T. Kawaji, T. Inoue, S. Hino, M. Nakao, and H. Tanihara.
- Journal Title
  
  Invest. Opthalmol. Vis. Sci.
  
  Volume: 57 Pages: 6461-6473
- DOI
  10.1167/iovs.16-19494
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04707, KAKENHI-PROJECT-26293375, KAKENHI-PROJECT-16K11290, KAKENHI-PROJECT-26462693, KAKENHI-PROJECT-15K15068, KAKENHI-PROJECT-15K06781, KAKENHI-PROJECT-16K07215
[Journal Article] Monocyte chemotactic protein-1 level in the aqueous humour as a prognostic factor for the outcome of trabeculectomy.2014
- Author(s)
  Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Clin Experiment Ophthalmol
  
  Volume: (in press) Pages: 334-341
- DOI
  10.1111/ceo.12204
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-23592610, KAKENHI-PROJECT-23791994, KAKENHI-PROJECT-25670735, KAKENHI-PROJECT-26293375, KAKENHI-PROJECT-26462693
[Journal Article] Monocyte chemotactic protein-1 level in the aqueous humour as a prognostic factor for the outcome of trabeculectomy2014
- Author(s)
  Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Clinical and Experimental Ophthalmology
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-23390403
[Journal Article] Tear fluid signs associated with filtration blebs as demonstrated by three-dimensional anterior segment optical coherence tomography2014
- Author(s)
  Kojima S, Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Clinical Ophthalmology
  
  Volume: 印刷中
- Data Source
  KAKENHI-PROJECT-23390403
[Journal Article] Long-term Outcomes and Complications of Trabeculectomy for Secondary Glaucoma in Patients with Familial Amyloidotic Polyneuropathy.2014
- Author(s)
  Kawaji T, Inoue T, Hara R, Eiki D, Ando Y, Tanihara H
- Journal Title
  
  PLoS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0096324
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-25462719, KAKENHI-PROJECT-25670735, KAKENHI-PROJECT-26293375, KAKENHI-PROJECT-26462664
[Journal Article] Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography.2014
- Author(s)
  Kojima S, Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Clinical Ophthalmology
  
  Volume: 8 Pages: 767-772
- DOI
  10.2147/opth.s59778
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-25670735, KAKENHI-PROJECT-26293375, KAKENHI-PROJECT-26462664
[Journal Article] Filtration Bleb Revision Guided by 3-Dimensional Anterior Segment Optical Coherence Tomography.2013
- Author(s)
  Kojima S, Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Journal of Glaucoma
  
  Volume: (in press)
- DOI
  10.1097/ijg.0b013e3182741ee6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-23659814, KAKENHI-PROJECT-23791994
[Journal Article] Elevated levels of multiple biomarkers of Alzheimer's disease in the aqueous humor of eyes with open-angle glaucoma.2013
- Author(s)
  Inoue T, Kawaji T, Tanihara H
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 54 Pages: 5353-5358
- DOI
  10.1167/iovs.13-12245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-23592610, KAKENHI-PROJECT-23791994, KAKENHI-PROJECT-25462719, KAKENHI-PROJECT-25670735
[Journal Article] Precise identification of filtration openings on the scleral flap by three-dimensional anterior segment optical coherence tomography.2012
- Author(s)
  Inoue T, Matsumura R, Kuroda U, Nakashima KI, Kawaji T, Tanihara H
- Journal Title
  
  Investigative Ophthalmology & VisualScience
  
  Volume: 53 Pages: 8288-8294
- DOI
  10.1167/iovs.12-10941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-23659814, KAKENHI-PROJECT-23791994
[Journal Article] 平成 23 年度日本眼科学会学術奨励賞受賞論文総説:家族性トランスサイレチン眼アミロイドーシスへの網膜光凝固術2012
- Author(s)
  川路隆博
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 116巻 Pages: 1046-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791993
[Journal Article] Simultaneous increases in multiple proinflammatory cytokines in the aqueous humor in pseudophakic glaucomatous eyes.2012
- Author(s)
  Inoue T, Kawaji T, Inatani M, Kameda T, Yoshimura N, Tanihara H
- Journal Title
  
  Cataract Refract Surg
  
  Volume: 38 Pages: 1389-1397
- DOI
  10.1016/j.jcrs.2012.04.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390403, KAKENHI-PROJECT-23592610, KAKENHI-PROJECT-23659814, KAKENHI-PROJECT-23791993, KAKENHI-PROJECT-23791994, KAKENHI-PROJECT-24390395, KAKENHI-PROJECT-24659758
[Journal Article] 平成23年度日本眼科学会学術奨励賞　受賞論文総説：家族性トランスサイレチン眼アミロイドーシスへの網膜光凝固術2012
- Author(s)
  川路隆博
- Journal Title
  
  日本眼科学会会誌
  
  Volume: 116 Pages: 1046-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791993
[Journal Article] Combined intravitreal bevacizumab and trabeculectomy with mitomycin C versus trabeculectomy with mitomycin C alone for neovascular glaucoma.2011
- Author(s)
  Takihara Y, Inatani M, Kawaji T, Fukushima M, Iwao K, Iwao M, Tanihara H.
- Journal Title
  
  Journal of Glaucoma 20(3)
  
  Pages: 196-201
- Data Source
  KAKENHI-PROJECT-20390449
[Journal Article] Ocular decompression retinopahy following trabeculectomy with mitomycin C associated with familial amyloidotic polyneuropathy.2006
- Author(s)
  Wakita M, Kawaji T, Ando E, Koga T, Inatani M, Ando Y, Tanihara H.
- Journal Title
  
  British Journal of Ophthalmology 90
  
  Pages: 515-516
- Data Source
  KAKENHI-PROJECT-18390470
[Journal Article] Combined intravitreal bevacizumab and trabeculectomy with mitomycin C versus trabeculectomy with mitomycin C alone for neovascular glaucoma
- Author(s)
  Takihara Y, Inatani M, Kawaji T, Fukushima M, Iwao K, Iwao M, Tanihara H.
- Journal Title
  
  Journal of Glaucoma (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390449
[Journal Article] Frequency and risk factors for intraocular pressure elevation after posterior sub-Tenon's capsule triamcinolone acetonide injection..
- Author(s)
  Iwao K, Inatani M, Kawaji T, Koga T, Mawatari Y, Tanihara H
- Journal Title
  
  Journal of Glaucoma 印刷中
- Data Source
  KAKENHI-PROJECT-18390470
[Journal Article] Effect of pivastatin on experimental choroidal neovascularization in rats
- Author(s)
  Sagara N, Kawaji T, Takano A, Inomata Y, Inatani M, Fukushima M, Tanihara H
- Journal Title
  
  Experimental Eye Research 印刷中
- Data Source
  KAKENHI-PROJECT-18390470
[Presentation] Evaluation of filtering blebs with transconjunctival oozing by anterior segment optical coherence tomography2013
- Author(s)
  Nakashima K, Inoue T, Fukushima A, Hirakawa S, Kawaji T, Tanihara H
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seattle, Washington, USA
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] Epithelial Mesenchymal Transition and Human Vitreous Samples in 2D and 3D culture of ARPE-19 cells2013
- Author(s)
  高橋枝里、猪俣泰也、川路隆博
- Organizer
  ARVO
- Place of Presentation
  米国・シアトル・ワシントン州立コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25462721
[Presentation] Filtration bleb-associated tear film sign demonstrated by three dimensional anterior segment optical coherent tomography2012
- Author(s)
  Kojima S, Inoue T, Kawaji T, Tanihara H
- Organizer
  European Glaucoma Society 2012
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] Filtration bleb revision guided by three-dimensional anterior segmental optical coherence tomography2012
- Author(s)
  Kojima S, Inoue T, Kawaji T, Tanihara H
- Organizer
  The 27th APAO Congress
- Place of Presentation
  Pusan, Korea
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] 家族性トランスサイレチン眼アミロイドーシスにおける網膜光凝固術の効果2012
- Author(s)
  川路隆博
- Organizer
  第116回日本眼科学会
- Place of Presentation
  東京国際フォーラム、東京
- Data Source
  KAKENHI-PROJECT-23791993
[Presentation] Pinpoint identification of filtration opening on the scleral flap margins created by trabeculectomy2012
- Author(s)
  Tanihara H, Inoue T, Kawaji T, Matsumura R, Kuroda U, Nakashima K
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] 線維柱帯切除術後症例における3 次元前眼部OCT による房水漏出点の同定2012
- Author(s)
  松村理世, 井上俊洋, 黒田詩子, 中島圭一, 川路隆博, 谷原秀信
- Organizer
  第23回日本緑内障学会
- Place of Presentation
  金沢石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] 3D AS-OCT を用いたトラベクレクトミー術後濾過胞の評価2012
- Author(s)
  小島祥, 井上俊洋, 川路隆博, 谷原秀信
- Organizer
  第23回日本緑内障学会
- Place of Presentation
  金沢石川県立音楽堂
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] Pinpoint identification of filtration opening on the scleral flap margins created by trabeculectomy2012
- Author(s)
  Inoue T, Kawaji T, Matsumura R, Kuroda U, Nakashima K, Tanihara H
- Organizer
  European Glaucoma Society 2012
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] Filtration bleb-associated tear film sign demonstrated by three dimensional anterior segment optical coherence tomography2012
- Author(s)
  Kojima S, Inoue T, Kawaji T, Kuroda U, Nakashima K, Matsumura R, Tanihara H
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] Diagnostic Usefulness of Indocyanine Green Fundus Angiography for Transthyretin-related Familial Amyloidotic Polyneuropathy.2012
- Author(s)
  Kawaji T
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-23390403
[Presentation] 血管新生緑内障に対する Bevacizumab 併用線維柱帯切除術の効果2009
- Author(s)
  瀧原祐史, 稲谷大, 川路隆博, 福島美紀子, 岩尾圭一郎, 岩尾奈子, 谷原秀信
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京都、東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-20390449
[Presentation] Combined intravitreal bevacizumab and trabeculectomy with mitomycin C versus trabeculectomy with mitomycin C for neovascular glaucoma.2009
- Author(s)
  Takihara Y, Inatani M, Kawaji T, Fukushima M, Iwao K, Iwao M, Tanihara H
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) Convention Center
- Place of Presentation
  Fort Lauderdale, Florida, USA
- Data Source
  KAKENHI-PROJECT-20390449

1. TANIHARA Hidenobu (60217148)

# of Collaborated Projects: 5 results

# of Collaborated Products: 25 results
2. INATANI Masaru (40335245)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
3. Takahashi Eri (60622602)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. INOUE Toshihiro (00317025)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
5. Inomata Yasuya (50452884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. KOGA Takahisa (70372787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. ITO Yasuhiro (70380996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 岩尾圭一郎 (30549118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HAYASHI Hodeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. HINO Shinjiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. HINO Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中尾光善

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAJI Takahiro 川路 隆博

Research Projects

Research Products

Co-Researchers

The regulation of bioactive molecule dynamics and development of real-time imaging technics for glaucoma therapy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

家族性眼アミロイドーシスの早期発見と手術合併症の克服に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research of epithelial-to-mesenchymal transition via redox regulation for age related macular degeneration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The effects of aqueous bioactive molecules on aqueous outflow dynamics and filtration-surgery results

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation for pathogenesis of glaucoma and the overcome of complications of filtering surgery via focusing on transthyretinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New therapeutic approach for glaucoma via drug-mediated bleb regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

初代網膜色素上皮培養細胞における形質転換および移植手術に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation for molecular mechanisms of aqueous humor outflow and the creation of new treatments for intraocular pressure elevation in glaucomatous eyes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Potential Neuroprotective Effects of an LSD1 Inhibitor in Retinal Ganglion Cells via p38 MAPK Activity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monocyte chemotactic protein-1 level in the aqueous humour as a prognostic factor for the outcome of trabeculectomy.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Monocyte chemotactic protein-1 level in the aqueous humour as a prognostic factor for the outcome of trabeculectomy2014

Author(s)

Journal Title

Data Source

[Journal Article] Tear fluid signs associated with filtration blebs as demonstrated by three-dimensional anterior segment optical coherence tomography2014

Author(s)

Journal Title

Data Source

[Journal Article] Long-term Outcomes and Complications of Trabeculectomy for Secondary Glaucoma in Patients with Familial Amyloidotic Polyneuropathy.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tear fluid signs associated with filtration blebs, as demonstrated by three-dimensional anterior segment optical coherence tomography.2014

Author(s)

Journal Title

DOI

Data Source

KAWAJI Takahiro 川路隆博

[Journal Article] 平成 23 年度日本眼科学会学術奨励賞受賞論文総説:家族性トランスサイレチン眼アミロイドーシスへの網膜光凝固術2012

[Journal Article] 平成23年度日本眼科学会学術奨励賞　受賞論文総説：家族性トランスサイレチン眼アミロイドーシスへの網膜光凝固術2012