Sekine Akihiro 関根章博

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SEKINE Akihiro 関根章博

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Researcher Number	30425631
Other IDs
Affiliation (Current)	2023: 千葉大学, 大学院医学研究院, 特任教授 2023: 京都大学, 医学研究科, 特定教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 千葉大学, 大学院医学研究院, 特任教授 2020 – 2021: 国立研究開発法人国立循環器病研究センター, 研究所, その他(移行) 2014 – 2021: 千葉大学, 予防医学センター, 教授 2019: 国立研究開発法人国立循環器病研究センター, オープンイノベーションセンター, 客員部長 2017: 千葉大学, 医学系研究院, 教授 … More 2016: 京都大学, 医学系研究科, 教授 2015 – 2016: 千葉大学, 学内共同利用施設等, 教授 2014: 京都大学, 大学院医学研究科, 教授 2013: 京都大学, 医学(系)研究科(研究院), 教授 2008 – 2011: Kyoto University, 医学研究科, 教授 Less
Review Section/Research Field	Principal Investigator Emergency medicine / Otorhinolaryngology / Applied pharmacology / Biological Sciences Except Principal Investigator Laboratory medicine / Basic Section 55060:Emergency medicine-related / Basic Section 59010:Rehabilitation science-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 54010:Hematology and medical oncology-related / Basic Section 49040:Parasitology-related … More / Pediatric surgery / Emergency medicine / Sports science / Applied pharmacology Less
Keywords	Principal Investigator 全ゲノム解析 / 全ゲノム配列決定 / PacBioRSⅡ / 敗血症ショック / long read型シーケンサ― / 全ゲノムシーケンス / データベ―ス / 変異 / PacBioRSⅡ/Sequel / 全ゲノム … More / 病原性微生物 / 敗血症 / パラメトリック解析 / ゲノム解析 / 原因遺伝子 / 難聴 / 原因未知 / 大家系 / パラメトリック連鎖解析 / 遺伝性難聴 / 新世代シークエンサー / 多型 / ゲノム配列 / ファーマコカイネティックス / ファーマコジェネティックス / Pharmacogenomics / Parmacogenomics / レスポンダー・ノンレスポンダー / 薬剤応答性 / Pharmacokinetics / トランスポーター / チトクロームP450 / レスポンダー/ノンレスポンダー / 副作用 / 次世代シークエンサー / ファーマコゲノミクス / 情報管理 / 前向き研究 / 疫学 / 健診情報管理 / コホート / ゲノム … More Except Principal Investigator 次世代シーケンサー / ゲノム / 敗血症 / 遺伝子多型 / 遺伝子 / 弾性線維腫 / 遺伝子検査学 / 網羅解析 / モデルマウス / メカノトランスダクション / 離島調査 / 原因遺伝子 / 家系調査 / Hirschsprung病 / 遺伝子解析 / 血栓症修飾遺伝子 / 第三世代シーケンサー / 血栓性素因 / 静脈血栓塞栓症 / 病原性 / 全ゲノム配列 / トキソプラズマ / 薬剤耐性 / 分子疫学 / 日和見感染症 / インターフェロンガンマノックアウトマウス / ゲノム解析 / トキソプラズマ症 / 慢性特発性偽性腸閉塞症 / 機能解析 / 次世代シークエンサー / 全エクソーム解析 / 遺伝性不整脈 / 遺伝子改変ゼブラフィッシュ / Crispr/Cas9システム / モルフォリノ / 次世代シークエンス / ゼブラフィッシュ / 個別化医療 / exon / 集中治療 / 救急 / EXON / single nucleotide polymorphisms / SNPs / IL-24 / IL-20 / IL-19 / IL-10 / GWAS / 肩運動 / 浸透率 / 家族性 / 画像診断 / 沖縄県 / 家系解析 / 副作用 / トランスレーショナルリサーチ / 薬剤反応性 / バイオマーカー Less

Integrated genome-wide association study in sepsis
- Principal Investigator
  
  中田孝明
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Chiba University
全ゲノム配列を用いたトキソプラズマ分子疫学情報の解明と病原性関連遺伝子の同定
- Principal Investigator
  
  野呂瀬一美
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Chiba University
第三世代シークエンサーを用いた血栓症の遺伝的背景の解明と診断・治療への活用
- Principal Investigator
  
  宮田敏行
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  National Cardiovascular Center Research Institute
Comprehensive genetic analysis of Hirschsprung disease by long-read sequence
- Principal Investigator
  
  照井慶太
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Chiba University
弾性線維腫の原因遺伝子同定とモデルマウス開発―病態解明に向けて
- Principal Investigator
  
  藤原作平
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Oita University
Whole genome sequencing of pathogenic microorganisms causing septic shockPrincipal Investigator
- Principal Investigator
  
  Sekine Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Emergency medicine
- Research Institution
  Chiba University
Genetic analysis of elastofibroma
- Principal Investigator
  
  Fujiwara Sakuhei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  Oita University
The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock.
- Principal Investigator
  
  Nakada Taka-aki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Emergency medicine
- Research Institution
  Chiba University
Study on quality, usefulness and ELSI of genetic testing including NGS analysis.
- Principal Investigator
  
  KOSUGI SHINJI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
Causative Gene of Chronic Intestinal Pseudo-obstruction
- Principal Investigator
  
  Terui Keita
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Chiba University
Development of a diagnostic method for severe cutaneous adverse reactions by genom biomarkers and their pathophysiological relevanceic
- Principal Investigator
  
  Saito Yoshiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Institute of Health Sciences
Genetic analysis for inherited arrhythmia and functional study using zebrafish model
- Principal Investigator
  
  Hayashi Kenshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Identification of causative genetic locus of a large family with hearing lossPrincipal Investigator
- Principal Investigator
  
  Sekine Akihiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
  Kyoto University
Evaluation of quality and usefullness of genetics testing-clinical application of next generation sequencer.
- Principal Investigator
  
  KOSUGI SHINJI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kyoto University
The establishment of accurate sequencing and genotyping systems of genes encoding drug metabolizing enzyme and transporter by using next generation sequencing system.Principal Investigator
- Principal Investigator
  
  SEKINE Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
ゲノム情報を統合したコホート研究における情報管理システムの構築Principal Investigator
- Principal Investigator
  
  関根章博
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] PacBioRSⅡを用いたインターフェロンフリー療法無効症例の原因となった変異の検出法2018
- Author(s)
  関根章博,竹田治彦,山下泰生,丸澤宏之
- Total Pages
  256
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-16H05496
[Book] 正確なサンガ法を行うために2018
- Author(s)
  関根章博,光永敏哉,真下陽一
- Total Pages
  322
- Publisher
  医学のあゆみ
- Data Source
  KAKENHI-PROJECT-16H05496
[Book] 最新内分泌代謝学「内分泌代謝疾患のゲノム、エピゲノム解析」2013
- Author(s)
  関根章博（監修：中尾一和）
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-25462637
[Book] Medical Science Digest特集分子疫学コホートと新たな予防医学の展開分子疫学研究とゲノム解析2011
- Author(s)
  関根章博
- Data Source
  KAKENHI-PROJECT-21390176
[Book] 特集分子疫学コホートと新たな予防医学の展開分子疫学研究とゲノム解析2011
- Author(s)
  関根章博
- Publisher
  Medical Science Digest
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] Comparison of the Diagnostic Value of Immunochromatography Kits in Corona Virus Disease 2019 Patients: A Prospective Pilot Study2021
- Author(s)
  Mitsunaga T, Seki Y, Yoshioka M, Suzuki I, Akita K, Mashiko S, Uzura M, Takeda S, Sekine A, Mashiko K.
- Journal Title
  
  JMA Journal
  
  Volume: 4 Issue: 1 Pages: 32-40
- DOI
  10.31662/jmaj.2020-0084
- NAID
  130007987345
- ISSN
  2433-328X, 2433-3298
- Year and Date
  2021-01-29
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Down syndrome cell adhesion molecule like-1 (DSCAML1) links the GABA system and seizure susceptibility.2020
- Author(s)
  Hayase Y, Amano S, Hashizume K, Tominaga T, Miyamoto H, Kanno Y, Ueno-Inoue Y, Inoue T, Yamada M, Ogata S, Balan S, Hayashi K, Miura Y, Tokudome K, Ohno Y, Nishijo T, Momiyama T, Yanagawa Y, Takizawa A, Mashimo T, Serikawa T, Sekine A, Nakagawa E, Takeshita E, Yoshikawa T, Waga C, Inoue K, Goto YI, Nabeshima Y, et al.
- Journal Title
  
  Acta Neuropathol Commun.
  
  Volume: 8 Issue: 1 Pages: 206-206
- DOI
  10.1186/s40478-020-01082-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-20K06667, KAKENHI-PROJECT-20K06886, KAKENHI-PROJECT-18KK0307, KAKENHI-INTERNATIONAL-16K21734, KAKENHI-ORGANIZER-16H06524, KAKENHI-PROJECT-18H03974, KAKENHI-PROJECT-17K07063, KAKENHI-PROJECT-17K07126, KAKENHI-PROJECT-18K07577, KAKENHI-PLANNED-16H06528, KAKENHI-PLANNED-16H06532, KAKENHI-PROJECT-18H02538
[Journal Article] Association of HLA-DRB1*04:05 allele with drug-induced interstitial lung disease in Japanese population.2020
- Author(s)
  Imatoh T, Ushiki A, Ota M, Ito M, Sekine A, Yamashita T, Mashimo Y, Nakamura R, Saito K, Saito Y, Hanaoka M.
- Journal Title
  
  Pharmacogenomics J.
  
  Volume: 20 Issue: 6 Pages: 823-830
- DOI
  10.1038/s41397-020-0172-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Single-molecular real-time deep sequencing reveals the dynamics of multidrug resistant haplotypes and structural variations in the hepatitis C virus genome.2020
- Author(s)
  Yamashita T, Takeda H, Takai A, Arasawa S, Nakamura F, Mashimo Y, Hozan M, Ohtsuru S, Seno H,Ueda Y, Sekine A
- Journal Title
  
  Sci. Rep,
  
  Volume: 10 Issue: 1 Pages: 2651-2651
- DOI
  10.1038/s41598-020-59397-2
- NAID
  120006844879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-18J00565, KAKENHI-PROJECT-16K09358, KAKENHI-PROJECT-17K09420
[Journal Article] Association of HLA-A*11:01 with sulfonamide-related severe cutaneous adverse reactions in Japanese patients.2020
- Author(s)
  Nakamura R, Ozeki T, Hirayama N, Sekine A, Yamashita T, Mashimo Y, Mizukawa Y, Shiohara T, Watanabe H, Sueki H, Ogawa K, Asada H, Kaniwa N, Tsukagoshi E, Matsunaga K, Niihara H, Yamaguchi Y, Aihara M, Mushiroda T, Saito Y, Morita E
- Journal Title
  
  J Invest Dermatol
  
  Volume: - Issue: 8 Pages: 1659-1662
- DOI
  10.1016/j.jid.2019.12.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-17K10250, KAKENHI-PROJECT-19K08755
[Journal Article] Descriptive epidemiology of high frequency component based on heart rate variability from 10-second ECG data and daily physical activity among community adult residents: the Nagahama Study2020
- Author(s)
  Takahashi N, Takahashi Y, Tabara Y, Kawaguchi T, Kuriyama A, Ueshima K, Kosugi S, Sekine A, Yamada R, Matsuda F, Nakayama T; Nagahama Study Group.
- Journal Title
  
  BioScience Trends
  
  Volume: 14 Issue: 4 Pages: 241-247
- DOI
  10.5582/bst.2020.03146
- NAID
  130007906541
- ISSN
  1881-7815, 1881-7823
- Year and Date
  2020-08-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-18K07411
[Journal Article] Age-Associated Changes in Value of the National Early Warning Score with the Japanese-Modified Glasgow Prognostic Score (NEWS-JmGPS) for Predicting In-Hospital Mortality of Elderly Patients Visiting the Emergency Department.2020
- Author(s)
  Mitsunaga T, Hasegawa I, Uzura M, Okuno K, Sekine A, Takeda S.
- Journal Title
  
  Arch Clinical Biomed Res
  
  Volume: 4 Pages: 001-016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Comparison of the National Early Warning Score (NEWS) and the Modified Early Warning Score (MEWS) for predicting admission and in-hospital mortality in elderly patients in the pre-hospital setting and in the emergency department.2019
- Author(s)
  Mitsunaga T, Hasegawa I, Uzura M, Okuno K, Otani K, Ohtaki Y, Sekine A, Takeda S.
- Journal Title
  
  PeerJ
  
  Volume: 7 Pages: e6947-e6947
- DOI
  10.7717/peerj.6947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07520
[Journal Article] Serum lipidomics for exploring biomarkers of bortezomib therapy in patients with multiple myeloma.2019
- Author(s)
  Maekawa K, Ri M, Nakajima M, Sekine A, Ueda R, Tohkin M, Miyata N, Saito Y, Iida S.
- Journal Title
  
  Cancer Sci
  
  Volume: 110 Issue: 10 Pages: 3267-3274
- DOI
  10.1111/cas.14178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-16K09855
[Journal Article] Exploring the hepatitis C virus genome using single molecule real-time sequencing.2019
- Author(s)
  Takeda H, Yamashita T, Ueda Y, Sekine A
- Journal Title
  
  World J Gastroenterol
  
  Volume: 25 Issue: 32 Pages: 4661-4672
- DOI
  10.3748/wjg.v25.i32.4661
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-16K09358, KAKENHI-PROJECT-17K09420
[Journal Article] Reduction in Gastroesophageal Reflux Disease Symptoms Is Associated with <i>Miso</i> Soup Intake in a Population-Based Cross-Sectional Study: The Nagahama Study2018
- Author(s)
  MANO Fumika、IKEDA Kaori、SATO Tosiya、NAKAYAMA Takeo、TANAKA Daisuke、JOO Erina、TAKAHASHI Yoshimitsu、KOSUGI Shinji、SEKINE Akihiro、TABARA Yasuharu、MATSUDA Fumihiko、INAGAKI Nobuya、Nagahama Study Group
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 64 Issue: 5 Pages: 367-373
- DOI
  10.3177/jnsv.64.367
- NAID
  130007501995
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2018-10-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07411, KAKENHI-PROJECT-18K08509, KAKENHI-PROJECT-16H05496, KAKENHI-PROJECT-17H04123
[Journal Article] Dietary habits associated with reduced insulin resistance: The Nagahama study.2018
- Author(s)
  Ikeda K, Sato T, Nakayama T, Tanaka D, Nagashima K, Mano F, Joo E, Fujimoto S, Takahashi Y, Kosugi S, Sekine A, Tabara Y, Matsuda F, Inagaki N; Nagahama Study Group.
- Journal Title
  
  Diabetes Res Clin Pract.
  
  Volume: 141 Pages: 26-34
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05496
[Journal Article] Risks and Cough-Aggravating Factors in Prolonged Cough: Epidemiological Observations from the Nagahama Cohort Study.2017
- Author(s)
  Matsumoto H, Izuhara Y, Niimi A, Tabara Y, Nagasaki T, Kanemitsu Y, Murase K, Oguma T, Ito I, Muro S, Sekine A, Matsuda F, Kosugi S, Nakayama T, Chin K, Mishima M; Nagahama Study Collaboration Group..
- Journal Title
  
  Ann Am Thorac Soc.
  
  Volume: Feb 10. Issue: 5 Pages: 698-705
- DOI
  10.1513/annalsats.201608-616bc
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05496, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-16K09536, KAKENHI-PROJECT-17H04123
[Journal Article] Evolution of multi-drug resistant HCV clones from pre-existing resistant-associated variants during direct-acting antiviral therapy determined by third-generation sequencing.2017
- Author(s)
  Takeda H, Ueda Y, Inuzuka T, Yamashita Y, Osaki Y, Nasu A, Umeda M, Takemura R, Seno H, Sekine A, Marusawa H.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 45605-45605
- DOI
  10.1038/srep45605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J11897, KAKENHI-PROJECT-16K09357, KAKENHI-PROJECT-16H05496
[Journal Article] Combined association of clinical and lifestyle factors with non-restorative sleep: The Nagahama Study.2017
- Author(s)
  Matsumoto T, Tabara Y, Murase K, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda F, Chin K.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 3 Pages: e0171849-e0171849
- DOI
  10.1371/journal.pone.0171849
- NAID
  120006539727
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-26293198, KAKENHI-PROJECT-26507006, KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-17H00872, KAKENHI-PROJECT-16H05496
[Journal Article] Hypothalamic AMP-Activated Protein Kinase Regulates Biphasic Insulin Secretion from Pancreatic β Cells during Fasting and in Type 2 Diabetes.2016
- Author(s)
  Kume S, Kondo M, Maeda S, Nishio Y, Yanagimachi T, Fujita Y, Haneda M, Kondo K, Sekine A, Araki SI, Araki H, Chin-Kanasaki M, Ugi S, Koya D, Kitahara S, Maeda K, Kashiwagi A, Uzu T, Maegawa H.
- Journal Title
  
  EBioMedicine.
  
  Volume: 13 Pages: 168-180
- DOI
  10.1016/j.ebiom.2016.10.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05496
[Journal Article] Relationship Among Chlamydia and Mycoplasma Pneumoniae Seropositivity, IKZF1 Genotype and Chronic Obstructive Pulmonary Disease in A General Japanese Population: The Nagahama Study.2016
- Author(s)
  Muro S, Tabara Y, Matsumoto H, Setoh K, Kawaguchi T, Takahashi M, Ito I, Ito Y, Murase K, Terao C, Kosugi S, Yamada R, Sekine A, Nakayama T, Chin K, Mishima M, Matsuda F; Nagahama Study Group.
- Journal Title
  
  Medicine (Baltimore).
  
  Volume: 95(15) Issue: 15 Pages: e3371-e3371
- DOI
  10.1097/md.0000000000003371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05496, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-15K08646
[Journal Article] Synergistic association of elevated serum free fatty acid and glucose levels with large arterial stiffness in a general population: The Nagahama Study2016
- Author(s)
  Yasuharu Tabara, Yoshimitsu Takahashi, Kazuya Setoh, Takahisa Kawaguchi, Norimoto Gotoh, Chikashi Terao, Ryo Yamada, Shinji Kosugi, Akihiro Sekine, Takeo Nakayama, Fumihiko Matsuda, on behalf of the Nagahama Study group.
- Journal Title
  
  M E T A B O L I S M C L I N I C A L A N D E X P E R I M E N T A L
  
  Volume: 65 Issue: 1 Pages: 66-72
- DOI
  10.1016/j.metabol.2015.10.011
- NAID
  120005698009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-16H05496
[Journal Article] Mouth Breathing, another Risk Factor for Asthma: the Nagahama Study.2016
- Author(s)
  Yumi I, Matsumoto H, Nagasaki T, Kanemitsu Y, Murase K, Ito I, Oguma T, Muro S, Asai K, Tabara Y, Takahashi K, Bessho K, Sekine A, Kosugi S, Yamada R, Nakayama T, Matsuda F, Niimi A, Chin K, Mishima M; Nagahama Study Group.
- Journal Title
  
  Allergy
  
  Volume: 未定 Issue: 7 Pages: 1031-1036
- DOI
  10.1111/all.12885
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23591117, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-16H05496, KAKENHI-PROJECT-15K08646
[Journal Article] Central blood pressure relates more strongly to retinal arteriolar narrowing than brachial blood pressure: the Nagahama Study.2015
- Author(s)
  Kumagai K1, Tabara Y, Yamashiro K, Miyake M, Akagi-Kurashige Y, Oishi M, Yoshikawa M, Kimura Y, Tsujikawa A, Takahashi Y, Setoh K, Kawaguchi T, Terao C, Yamada R, Kosugi S, Sekine A, Nakayama T, Matsuda F, Yoshimura N; Nagahama Study group
- Journal Title
  
  J Hypertens
  
  Volume: 33 Issue: 2 Pages: 323-9
- DOI
  10.1097/hjh.0000000000000391
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-26670313, KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-25462637
[Journal Article] Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population-the Nagahama study.2015
- Author(s)
  C Terao, K Asai; M Hashimoto; T Yamazaki; K Ohmura; A Yamaguchi; K Takahashi; N Takei; T Ishii; T Kawaguchi; Y Tabara; M Takahashi; T Nakayama; S Kosugi; A Sekine; T Fujii; R Yamada; T Mimori; F Matsuda; K Bessho, Nagahama Study Group.
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: 59 Pages: 85-90
- DOI
  10.1016/j.jaut.2015.03.002
- NAID
  120005601013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-26460649, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25463081, KAKENHI-PROJECT-25293141
[Journal Article] Descriptive epidemiology of spot urine sodium-to-potassium ratio clarified close relationship with blood pressure level: the Nagahama study.2015
- Author(s)
  Tabara Y, Takahashi Y, Kumagai K, Setoh K, Kawaguchi T, Takahashi M, Muraoka Y, Tsujikawa A, Gotoh N, Terao C, Yamada R, Kosugi S, Sekine A, Yoshimura N, Nakayama T, Matsuda F; Nagahama study group.
- Journal Title
  
  J Hypertens
  
  Volume: 33 Issue: 12 Pages: 2407-13
- DOI
  10.1097/hjh.0000000000000734
- NAID
  120005712944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-26670313, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293141
[Journal Article] Significant association of periodontal disease with anti-citrullinated peptide antibody in a Japanese healthy population -the Nagahama study.2015
- Author(s)
  C Terao, K Asai; M Hashimoto; T Yamazaki; K Ohmura; A Yamaguchi; K Takahashi; N Takei; T Ishii; T Kawaguchi; Y Tabara; M Takahashi; T Nakayama; S Kosugi; A Sekine; T Fujii; R Yamada; T Mimori; FMatsuda; K Bessho.
- Journal Title
  
  Journal of Autoimmunity
  
  Volume: in press
- NAID
  120005601013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590694
[Journal Article] Knee Pain and Low Back Pain Additively Disturb Sleep in the General Population: A Cross-Sectional Analysis of the Nagahama Study.2015
- Author(s)
  Murase K, Tabara Y, Ito H, Kobayashi M, Takahashi Y, Setoh K, Kawaguchi T, Muro S, Kadotani H, Kosugi S, Sekine A, Yamada R, Nakayama T, Mishima M, Matsuda S, Matsuda F, Chin K.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 10 Pages: e0140058-e0140058
- DOI
  10.1371/journal.pone.0140058
- NAID
  120005756275
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-26507006, KAKENHI-PROJECT-25461156, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-26293198
[Journal Article] Japan Pharmacogenomics Data Science Consortium. Development of a simple genotyping method for the HLA-A*31:01-tagging SNP in Japanese.2015
- Author(s)
  Maekawa K, Nakamura R, Kaniwa N, Mizusawa S, Kitamoto A, Kitamoto T, Ukaji M, Matsuzawa Y, Sugiyama E, Uchida Y, Kurose K, Ueta M, Sotozono C, Ikeda H, Yagami A, Matsukura S, Kinoshita S, Muramatsu M, Ikezawa Z, Sekine A, Furuya H, Takahashi Y, Matsunaga K, Aihara M, Saito Y
- Journal Title
  
  Pharmacogenomics.
  
  Volume: 16 Issue: 15 Pages: 1689-1699
- DOI
  10.2217/pgs.15.115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293355, KAKENHI-PROJECT-26293122, KAKENHI-PROJECT-15K19168
[Journal Article] Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels.2015
- Author(s)
  146.Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels. Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F.
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 7754-7754
- DOI
  10.1038/ncomms8754
- NAID
  120005743662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-25253059, KAKENHI-PROJECT-25461156, KAKENHI-PROJECT-25462637, KAKENHI-PROJECT-25293141
[Journal Article] 7C.07: ASSOCIATION OF SERUM FREE FATTY ACID LEVEL WITH REDUCED REFLECTION PRESSURE WAVE MAGNITUDE AND CENTRAL BLOOD PRESSURE: THE NAGAHAMA STUDY.2015
- Author(s)
  Tabara Y, Takahashi Y, Kawaguchi T, Setoh K, Terao C, Yamada R, Kosugi S, Sekine A, Nakayama T, Matsuda F.
- Journal Title
  
  J Hypertens
  
  Volume: 33 Suppl Issue: Supplement 1 Pages: e98-e98
- DOI
  10.1097/01.hjh.0000467614.38730.87
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-25462637
[Journal Article] IKZF1, a new susceptibility gene for cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvements.2015
- Author(s)
  Ueta M, Sawai H, Sotozono C, Hitomi Y, Kaniwa N, Kim MK, Seo KY, Yoon KC, Joo CK, Kannabiran C, Wakamatsu TH, Sangwan V, Rathi V, Basu S, Ozeki T, Mushiroda T, Sugiyama E, Maekawa K, Nakamura R, Aihara M, Matsunaga K, Sekine A, Gomes JÁP, Hamuro J, Saito Y, Kubo M, Kinoshita S, Tokunaga K.
- Journal Title
  
  J. Allergy Clin. Immunol.
  
  Volume: 未定 Issue: 6 Pages: 03744-0
- DOI
  10.1016/j.jaci.2014.12.1916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22133008, KAKENHI-PROJECT-25293355, KAKENHI-PROJECT-25460082, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-25462637
[Journal Article] Airflow limitation in smokers is associated with arterial stiffness: The nagahama study2014
- Author(s)
  Tabara, Y., Muro, S., Takahashi, Y., Setoh, K., Kawaguchi, T., Terao, C., Yamada, R.,. . . Nagahama Study Group
- Journal Title
  
  Atherosclerosis
  
  Volume: 232 Issue: 1 Pages: 59-64
- DOI
  10.1016/j.atherosclerosis.2013.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590379, KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25293141
[Journal Article] Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population: The Nagahama Study.2014
- Author(s)
  Murase, K., Tabara, Y., Takahashi, Y., Muro, S., Yamada, R., Setoh, K., Kawaguchi, T., Kadotani, H., Kosugi, S., Sekine, A., Nakayama, T., Mishima, M., Chiba, T., Chin, K., Matsuda, F
- Journal Title
  
  Sleep
  
  Volume: 37 Issue: 11 Pages: 1809-15
- DOI
  10.5665/sleep.4176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-26293198, KAKENHI-PROJECT-26507006
[Journal Article] Airflow limitation in smokers is associated with arterial stiffness: The Nagahama Study.2014
- Author(s)
  Tabara Y., Muro S., Takahashi Y., Setoh K., Kawaguchi T., Terao C., Kosugi S., Sekine A., Yamada R., Nakayama T., Mishima M., Matsuda F. : Nagahama Study Group.
- Journal Title
  
  Atherosclerosis
  
  Volume: 232 Pages: 59-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Association of Serum–Free Fatty Acid Level With Reduced Reflection Pressure Wave Magnitude and Central Blood Pressure. The Nagahama Study.2014
- Author(s)
  Yasuharu Tabara, Yoshimitsu Takahashi, Takahisa Kawaguchi, Kazuya Setoh, Chikashi Terao, Ryo Yamada, Shinji Kosugi, Akihiro Sekine, Takeo Nakayama, Fumihiko Matsuda on behalf of the Nagahama Study Group.
- Journal Title
  
  Hypertension
  
  Volume: 64 Issue: 6 Pages: 1212-8
- DOI
  10.1161/hypertensionaha.114.04277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590694
[Journal Article] An association between anti-nuclear antibodies and HLA class II locus and heterogeneous characteristics of staining patterns: The Nagahama Study.2014
- Author(s)
  Terao C, Ohmura K, Yamada R, Kawaguchi T, Shimizu M, Tabara Y, Takahashi M, Setoh K, Nakayama T, Kosugi S, Sekine A, Matsuda F, Tsuneyo Mimori T on behalf of the Nagahama Study Group.
- Journal Title
  
  Arthritis Rheumatol.
  
  Volume: 66 Issue: 3_suppl Pages: 3395-403
- DOI
  10.1177/0022034514559127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25463081, KAKENHI-PROJECT-25670856, KAKENHI-PROJECT-26507006, KAKENHI-PROJECT-15K08646, KAKENHI-PROJECT-26430192, KAKENHI-PROJECT-25462637
[Journal Article] ffects of smoking and shared epitope on the production of anti-citrullinated peptide antibody in a Japanese adultpopulation.2014
- Author(s)
  Terao C, Ohmura K, Ikari K, Kawaguchi T, Takahashi M, Setoh K, Nakayama T,Kosugi S, Sekine A, Tabara Y, Taniguchi A, Momohara S, Yamanaka H, Yamada R,Matsuda F, Mimori T; Nagahama Study Group
- Journal Title
  
  Arthritis Care Res (Hoboken)
  
  Volume: 66 Issue: 12 Pages: 1818-27
- DOI
  10.1002/acr.22385
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390360, KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-24592285, KAKENHI-PROJECT-25293141
[Journal Article] Association of Longer QT Interval With Arterial Waveform and Lower Pulse Pressure Amplification: The Nagahama Study.2013
- Author(s)
  Tabara Y., Takahashi Y., Kohara K., Setoh K., Kawaguchi T., Terao C., Igase M., Yamada R., Kosugi S., Sekine A., Miki T., Nakayama T., Matsuda F.; Nagahama Study Group.
- Journal Title
  
  Am. J. Hypertens.
  
  Volume: 26 Pages: 973-980
- NAID
  120005474538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Mastication and risk for diabetes in a Japanese population: a cross-sectional study.2013
- Author(s)
  Yamazaki T., Yamori M., Asai K., Nakano-Araki I., Yamaguchi A., Takahashi K., Sekine A., Matsuda F., Kosugi S., Nakayama T., Inagaki N., Bessho K.; Nagahama Study Collaboration Group.
- Journal Title
  
  PLoS One.
  
  Volume: 8
- NAID
  120005296012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Prevalence of postmicturition urinary incontinence in Japanese men: Comparison with other types of incontinence.2013
- Author(s)
  Yoshimura K., Nakayama T., Sekine A., Matsuda F., Kosugi S., Sugino Y., Yoshimura K., Ogawa O.
- Journal Title
  
  Int. J .Urol.
  
  Volume: 20 Pages: 911-916
- NAID
  10031195893
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: The Nagahama Study.2013
- Author(s)
  Tabara Y., Takahashi Y., Setoh K., Muro S., Kawaguchi T., Terao C., Kosugi S., Sekine A., Yamada R., Mishima M., Nakayama T., Matsuda F.
- Journal Title
  
  Int. J. Cardiol.
  
  Volume: 168 Pages: 2673-2677
- NAID
  120005343927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Increased aortic wave reflection and smaller pulse pressure amplification in smokers and passive smokers confirmed by urinary cotinine levels: the Nagahama Study.2013
- Author(s)
  Yasuharu Tabara, Yoshimitsu Takahashi, Kazuya Setoh, Shigeo Muro, Takahisa Kawaguchi, Chikashi Terao, Shinji Kosugi, Akihiro Sekine, Ryo Yamada, Michiaki Mishima, Takeo Nakayama, and Fumihiko Matsuda, on behalf of the Nagahama Study Group
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 168(3) Issue: 3 Pages: 2673-2677
- DOI
  10.1016/j.ijcard.2013.03.028
- NAID
  120005343927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25293141
[Journal Article] Association of longer QT interval with arterial waveform and lower pulse pressure amplification: the Nagahama Study.2013
- Author(s)
  Tabara Y, Takahashi Y, Kohara K, Setoh K, Kawaguchi T, Terao C, Igase M, Yamada R, Kosugi S, Sekine A, Miki T, Nakayama T, Matsuda F; Nagahama Study Group.
- Journal Title
  
  Am J Hypertens
  
  Volume: 26 Issue: 8 Pages: 973-980
- DOI
  10.1093/ajh/hpt052
- NAID
  120005474538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390188, KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-25670353
[Journal Article] Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.2013
- Author(s)
  Kitamoto T., Kitamoto A., Yoneda M., Hyogo H., Ochi H., Nakamura T., Teranishi H., Mizusawa S., Ueno T., Chayama K., Nakajima A., Nakao K., Sekine A., Hotta K.
- Journal Title
  
  Hum. Genet.
  
  Volume: 132 Pages: 783-792
- NAID
  120005474457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462637
[Journal Article] Mastication and risk for diabetes in a Japanese population: a cross-sectional study.2013
- Author(s)
  Yamazaki T, Yamori M, Asai K, Nakano-Araki I, Yamaguchi A, Takahashi K, Sekine A, Matsuda F, Kosugi S, Nakayama T, Inagaki N, Bessho K; Nagahama Study Collaboration Group.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 6 Pages: e64113-e64113
- DOI
  10.1371/journal.pone.0064113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591672, KAKENHI-PROJECT-24590694, KAKENHI-PROJECT-24592985, KAKENHI-PROJECT-25293141, KAKENHI-PROJECT-25463081, KAKENHI-PROJECT-25670856
[Journal Article] Prevalence of postmicturition urinary incontinence in Japanese men: Comparison with other types of incontinence.2013
- Author(s)
  Yoshimura K, Nakayama T, Sekine A, Matsuda F, Kosugi S, Sugino Y, Yoshimura K, Ogawa O; Nagahama Cohort Research Group.
- Journal Title
  
  Int J Urol
  
  Volume: 20 Issue: 9 Pages: 911-916
- DOI
  10.1111/iju.12074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591672, KAKENHI-PROJECT-24590694
[Journal Article] Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from East and South Asians2012
- Author(s)
  Li H・Sekine A
- Journal Title
  
  Diabetologia
  
  Volume: 55 Pages: 981-995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] 薬剤応答性の違いを調査するためのPharmacokinetics関連遺伝子群の日本人における高精度遺伝子型およびゲノム配列決定法の確立2012
- Author(s)
  関根章博・・水澤精穂
- Journal Title
  
  日本遺伝カウセリング学会誌
  
  Volume: 33巻1号 Pages: 7-12
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] Genetic variations in the CYP17A1and NT5C2 genes are associated with areduction in visceral and subcutaneous fatareas in Japanese women2012
- Author(s)
  Hotta K・Mizusawa S・Sekine A
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Pages: 46-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] B-type Natriuretic peptide as an independent correlate of nocturnal voiding in Japanese women2012
- Author(s)
  Yoshimura K・Sekine A
- Journal Title
  
  Neurourol Urodyn
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population2011
- Author(s)
  Hotta K・Mizusawa S・Sekine A
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Pages: 647-651
- NAID
  10030660817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] 次世代シークエンサー2011
- Author(s)
  関根章博、前田士郎
- Journal Title
  
  Diabetes Journal
  
  Volume: 39 Pages: 143-147
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] Computed tomography analysis of the association between the SH2B1rs7498665 single-nucleotide polymorphism and visceral fat area2011
- Author(s)
  Hotta K・Mizusawa S・Sekine A
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Pages: 716-719
- NAID
  10030661293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Journal Article] Association of the rs738409polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease2010
- Author(s)
  Hotta K・Mizusawa S・Sekine A
- Journal Title
  
  BMC Med Genet
  
  Volume: 11 Pages: 172-172
- NAID
  120002949731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176
[Presentation] アンチトロンビン抵抗性を示すプロトロンビン変異を伴う３症例の検討2021
- Author(s)
  辻明宏、関根章博、浅野遼太郎、上田仁、青木竜男、保山美由紀、根木玲子、小亀浩市、宮田敏行、大郷剛
- Organizer
  第43回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] Genetic study for idiopathic venous thromboembolism in Japanese using short-read and long read sequencers, a pilot study of Japanese Group of Idiopathic Thromboembolism2020
- Author(s)
  Tsuji A, Sekine A, Wada H, Morishita E. Ogihara Y, Nogami K, Kojima T, Matsushita T, Yamada N, Ogo T, Neki R, Kokame K, Yasuda S, MiyataT
- Organizer
  The XXVIII Congress of the International Society on Thrombosis and Haemostasis (ISTH 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] 特発性血栓症患者のゲノム情報を用いた層別化による病態解明研究2020
- Author(s)
  辻明宏、和田英夫、森下英理子、野上恵嗣、荻原義人、松下正、小嶋哲人、大郷剛、根木玲子、小亀浩市、安田聡、関根章博、宮田敏行
- Organizer
  第42回日本血栓止血学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08875
[Presentation] レジストリ研究からみる特発性血栓症患者の特徴2019
- Author(s)
  辻明宏、宮田敏行、関根章博
- Organizer
  第13回日本血栓止血学会各術標準化委員会シンポジウム
- Data Source
  KAKENHI-PROJECT-16H05496
[Presentation] シーケンス・タイピングを用いた遺伝子診断における精度低下を招く問題点と改善点2017
- Author(s)
  関根章博、山下泰生、北原輝栄、竹村亮、羽田明
- Organizer
  第24回日本遺伝子診療学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05496
[Presentation] 次世代シーケンサーを用いた慢性特発性偽性腸閉塞症の原因遺伝子探索2017
- Author(s)
  照井慶太，関根章博，山下泰生，北原輝栄，竹村亮，真下陽一，齋藤武，中田光政，小松秀吾，羽田明，吉田英生
- Organizer
  第54回日本小児外科学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10918
[Presentation] AIを想定した医療ビックデータの収集解析2017
- Author(s)
  関根章博、山下泰生、竹村亮、真下陽一、井上正宏
- Organizer
  日本動物実験代替法学会第30回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05496
[Presentation] Third-generation sequencing unveils the evolution of multi-drug resistant hepatitis C virus clones during direct-acting antiviral therapy.2017
- Author(s)
  Haruhiko Takeda, Yoshihide Ueda, Tadashi Inuzuka, Shigeru Ohtsuru, Hiroshi Seno, Akihiro Sekine and Hiroyuki Marusawa.
- Organizer
  American Association for Study of Liver Diseases (AASLD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05496
[Presentation] Serum lipid metabolomics can predict sensitivity to bortezomib treatment in multiple myeloma2016
- Author(s)
  Masaki Ri, Kazuo Okemoto, Keiko Maekawa, Takashi Ishida, Miki Nakajima, Akihiro Sekine, Ryuzo Ueda, Masahiro Tohkin, Naoki Miyata, Yoshiro Saito, Shinsuke Iida
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  神奈川横浜市西区パシフィコ横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16H05496
[Presentation] 弾性線維腫の大家系パラメトリック連鎖解析による原因遺伝子の探索2016
- Author(s)
  関根章博
- Organizer
  第98回日本皮膚科学会大分地方会
- Place of Presentation
  ホルトホール大分（大分市）
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-15K01621
[Presentation] 特別講演１：弾性線維腫の大家系パラメトリック連鎖解析による原因遺伝子の探索2016
- Author(s)
  関根章博、竹村亮、真下陽一、北原輝栄、藤原作平
- Organizer
  第98回日本皮膚科学会大分地方会
- Place of Presentation
  大分県労働福祉会館ソレイユ（大分県・大分市）
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] ショートリードを用いたWhole Genome Sequenceで得られた変異に対する評価.2015
- Author(s)
  竹村亮, 北原輝栄, 関根章博
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  京王プラザホテル（東京都・新宿）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] 遺伝カウンセリングに必要な全ゲノム解析情報の精度と検証2015
- Author(s)
  関根章博、竹村亮、真下陽一、北原輝栄、山下泰生、羽田明
- Organizer
  第39回日本遺伝カウンセリング学会各術集会
- Place of Presentation
  三井ガーデンホテル千葉（千葉県・千葉市）
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] Establishment of an accurate genome sequencing method combining next generation short-read (Hisq, Miseq) and long-read (PacBio) sequencers2013
- Author(s)
  sekine A.
- Organizer
  ＯｋｉｎａｗａＩｎｔｅｒｎａｔｉｏｎａｌＰｒｏｊｙｅｃｔｆｏｒＣｏｎｓｔｒｕｃｔｉｏｎｏｆＩｎｔｅｌｌｅｃｔｕａｌＣｌｕｓｔｅｒａｎｄＩｎｄｕｓｔｒｙｂａｓｅｄ on Advanced Genomic Research.
- Place of Presentation
  okinawa naha
- Invited
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] 医薬品副作用情報データベースを用いた横紋筋融解症の要因検討2013
- Author(s)
  中國正祥、関根章博、水澤精穂、寺西啓、柴田有花、土屋実央、小杉眞司
- Organizer
  第37回日本遺伝カウンセリング学会
- Place of Presentation
  神奈川県川崎
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] 先天性難聴の遺伝学的検査における症例調査2013
- Author(s)
  中國正祥、北尻真一郎、谷口美玲、岡野高之、村上裕美、関根章博、柴田有花、土屋未央、小杉眞司
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  宮城県仙台
- Data Source
  KAKENHI-PROJECT-25462637
[Presentation] 薬剤応答性の違いを調査するためのPharmacokinetics関連遺伝子群の日本人における高精度遺伝子型およびゲノム配列決定法の確立2011
- Author(s)
  関根章博, 他8名
- Organizer
  遺伝医学合同学術集会2011
- Place of Presentation
  京都大学百周年時計台記念館(招待講演)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21390176
[Presentation] 薬剤応答性の違いを調査するためのPharmacokinetics関連遺伝子群の日本人における高精度遺伝子型およびゲノム配列決定法の確立2011
- Author(s)
  関根章博・水澤精穂
- Organizer
  遺伝医学合同学術集会2011
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-21390176
[Presentation] コホート研究における医療情報の収集～長浜コホートをフィールドとして～2010
- Author(s)
  関根章博, 他
- Organizer
  第18回理化学研究所理事長ファンドワークショップ
- Place of Presentation
  湘南国際村
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20018012
[Presentation] ゲノム疫学コホート研究を実現する情報管理システムの構築2009
- Author(s)
  関根章博, 他
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-20018012
[Presentation] 長浜0次予防コホート事業における情報管理について2009
- Author(s)
  関根章博, 他
- Organizer
  東海大学医学研究科教育者教養セミナー
- Place of Presentation
  東海大学伊勢原校舎
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20018012
[Presentation] 長浜コホート研究における情報管理システム～プライバシー保護、正確かっ欠損の少ない情報取得を目指して～2009
- Author(s)
  関根章博, 他
- Organizer
  生命倫理シンポジウム
- Place of Presentation
  霞が関ビル
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20018012
[Presentation] 先天性難聴の遺伝子診断における症例調査
- Author(s)
  中國正祥、北尻真一郎、谷口美玲、岡野高之、村上裕美、関根章博、柴田有花、土屋実央、小杉眞司
- Organizer
  日本人類遺伝学会第58回大会
- Place of Presentation
  仙台市、江陽グランドホテル
- Data Source
  KAKENHI-PROJECT-24590694
[Presentation] 日本人におけるカルバマゼピン誘因性薬疹発症の危険因子HLA-A*31:01 のサロゲートマーカー多型を対象としたタイピング系の構築．
- Author(s)
  前川京子, 水澤精穂, 北本綾, 北本卓也, 中村亮介, 杉山永見子, 上田真由美, 外園千恵, 池田浩子, 矢上晶子, 松倉節子, 木下茂, 村松正明, 古谷博和, 高橋幸利, 松永佳世子, 相原道子, 関根章博, 日本PGX データサイエンスコンソーシアム, 斎藤嘉朗
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26293122
[Presentation] 副作用情報データベースを用いた　横紋筋融解症に関するゲノム薬理学的研究
- Author(s)
  中國正祥、関根章博、水澤精穂、寺西啓、柴田有花、土屋実央、小杉眞司
- Organizer
  第37回日本遺伝カウンセリング学会学術集会
- Place of Presentation
  川崎市産業振興会館
- Data Source
  KAKENHI-PROJECT-24590694

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Sekine Akihiro 関根 章博

SEKINE Akihiro 関根 章博

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Whole genome sequencing of pathogenic microorganisms causing septic shockPrincipal Investigator

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Identification of causative genetic locus of a large family with hearing lossPrincipal Investigator

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The establishment of accurate sequencing and genotyping systems of genes encoding drug metabolizing enzyme and transporter by using next generation sequencing system.Principal Investigator

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Sekine Akihiro 関根章博

SEKINE Akihiro 関根章博