Tachibana Masahito 立花眞仁

… Alternative Names

TACHIBANA Masahito 立花眞仁

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Researcher Number	30431571
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東北大学, 医学系研究科, 准教授 2018 – 2020: 東北大学, 大学病院, 准教授 2016 – 2018: 東北大学, 大学病院, 講師 2015: 東北大学, 大学病院, 助教 2014: 東北大学, 医学(系)研究科(研究院), 非常勤講師
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 核移植 / 細胞質移植 / 卵子凍結 / がん生殖 / ミトコンドリア / 卵子提供 / 生殖補助医療 / 凍結 / 細胞質置換 / 配偶子系列遺伝子治療 / 卵細胞質 / 生殖医学 … More Except Principal Investigator … More 精子 / 精液 / 男性不妊 / 生殖医学 / 出生コホート / 月経前症候群 / 月経痛 / ゲノムワイド関連解析（GWAS） / 体外受精（IVF）/顕微授精（ICSI） / 遺伝子異常 / ゲノム変化 / 三世代コホート調査 / 顕微授精（ICSI） / 体外受精（IVF） / 生殖補助医療（ART） / 顕微授精 / インプリンティング異常症 / 潜性遺伝病 / 父母アレル間遺伝子変換 / DNAパネル / SNP / Y染色体 / リファレンスパネル / ゲノム解析 / 活性酸素種 / インドール化合物 / 難治性不妊 / 受精能 / ATP / ミトコンドリア / 胚 / 卵子 / プロテオーム / プロテオミクス / 加齢卵 / NLB / SUMO / 卵母細胞 / SUMO化 / Bnc1 / Basonuclin1 Less

Challenge towards creation of oocyte via parthenogenetically replicated female genome (PRFG)Principal Investigator
- Principal Investigator
  
  立花眞仁
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Exploratory Study on Genomic Abnormalities Associated with Assisted Reproductive Technologies in a Three-Generation Cohort
- Principal Investigator
  
  Sugawara Atsushi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
大規模出生コホートから月経関連症状の長期的変化を捉える
- Principal Investigator
  
  渡邉善
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Study of utilization of MRT technique in assisted reproduction on cancer survivorPrincipal Investigator
- Principal Investigator
  
  Tachibana Masahito
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Study of overcoming severe infertility using novel indole acid compound, MA-5
- Principal Investigator
  
  Shiga Naomi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Preparation and Application of Y chromosome Panel using BirThree Cohort Men
- Principal Investigator
  
  Suzuki Kichiya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tohoku University
Challenge of overcoming recurrent IVF failure due to cytoplasmic dysfunction by MST: To secure safety in future generationPrincipal Investigator
- Principal Investigator
  
  TACHIBANA Masahito
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Analysis of nucleolus function and sumoylation in oocyte
- Principal Investigator
  
  IHARA Motomasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University
Proteomics analysis of semen obtained from male infertile patients
- Principal Investigator
  
  Suzuki Kichiya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] Clinical Bioenergetics 1st Edition（chapter 16）2020
- Author(s)
  Masahito Tachibana
- Total Pages
  716
- Publisher
  ELSEVIER
- ISBN
  9780128196212
- Data Source
  KAKENHI-PROJECT-19K09772
[Journal Article] Association of fish intake with menstrual pain: A cross-sectional study of the Japan Environment and Children’s Study2022
- Author(s)
  Yokoyama Emi、Takeda Takashi、Watanabe Zen、Iwama Noriyuki、Satoh Michihiro、Murakami Takahisa、Sakurai Kasumi、Shiga Naomi、Tatsuta Nozomi、Saito Masatoshi、Tachibana Masahito、Arima Takahiro、Kuriyama Shinichi、Metoki Hirohito、Yaegashi Nobuo
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 7 Pages: e0269042-e0269042
- DOI
  10.1371/journal.pone.0269042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09508
[Journal Article] Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryos2018
- Author(s)
  Masahito Tachibana, Takashi Kuno and Nobuo Yaegashi
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: Oct; 17(4) Issue: 4 Pages: 421-433
- DOI
  10.1002/rmb2.12230
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05468
[Journal Article] 核移植（ミトコンドリア移植）と研究倫理2017
- Author(s)
  立花眞仁
- Journal Title
  
  メディカルエシックス
  
  Volume: 54 Pages: 41-61
- Data Source
  KAKENHI-PROJECT-16H05468
[Journal Article] 成熟卵紡錘体置換（MST）方を用いた配偶子系列遺伝子治療確立へ向けて2017
- Author(s)
  立花眞仁
- Journal Title
  
  日本産科婦人科学会雑誌
  
  Volume: 69（11） Pages: 2241-2251
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] Utilization of cytoplasmic replacement techniques in assisted reproduction2023
- Author(s)
  Masahito Tachibana
- Organizer
  IFFS2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08793
[Presentation] 細胞質移植を用いた新たなART治療戦略の開発を目指して2023
- Author(s)
  立花眞仁
- Organizer
  第41回日本受精着床学会
- Data Source
  KAKENHI-PROJECT-23K08793
[Presentation] 魚の摂取頻度と月経痛の有病率の長期的検討　エコチル調査における宮城ユニットセンター追加調査2022
- Author(s)
  横山絵美, 武田卓, 渡邉善, 岩間憲之, 佐藤倫広, 村上任尚, 櫻井香澄, 志賀尚美, 龍田希, 齋藤昌利, 立花眞仁, 有馬隆博, 栗山進一, 目時弘仁, 八重樫伸生
- Organizer
  第37回日本女性医学学会学術集会
- Data Source
  KAKENHI-PROJECT-21K09508
[Presentation] 卵子凍結における卵子ゲノムの保存の挑戦 -第一極体自家移植による極体ゲノムの凍結融解ダメージ回避の試み2022
- Author(s)
  平賀裕章、菅原淳史、高橋藍子、佐藤壮樹、高橋友梨、虎谷惇平、横山絵美、志賀尚美、渡邉善、八重樫伸生、立花眞仁
- Organizer
  第59回東北生殖医学会
- Data Source
  KAKENHI-PROJECT-19K09772
[Presentation] ミトコンドリア置換法－原理と技術、前臨床試験2021
- Author(s)
  立花眞仁
- Organizer
  第20回ミトコンドリア学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09772
[Presentation] 魚摂取頻度はPMS/PMDDの有病率に関連する：エコチル調査における宮城ユニットセンター追加調査2021
- Author(s)
  横山絵美、武田卓、渡邉善、岩間憲之、齋藤昌利、星合哲郎、立花眞仁、目時弘仁、八重樫伸生
- Organizer
  第158回東北連合産科婦人科学会・第68回北日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09508
[Presentation] Association of frequency and preference of fish intake with dysmenorrhea：An adjunct study of the Japan Environment and Children's Study2021
- Author(s)
  Yokoyama Emi, Takeda Takashi, Watanabe Zen, Iwama Noriyuki, Saito Masatoshi, Hoshiai Tetsuro: Tachibana Masahito, Metoki Hirohito, Yaegashi Nobuo
- Organizer
  第73回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-21K09508
[Presentation] 細胞質置換/移植による卵細胞室機能低下克服への挑戦2020
- Author(s)
  立花　眞仁
- Organizer
  第38回日本受精着床学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09772
[Presentation] 発生工学研究から派生する生殖補助医療研究と新規治療開発の可能性2019
- Author(s)
  立花眞仁
- Organizer
  第19回日本生殖工学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 核移植が切り開く近未来のART2019
- Author(s)
  立花眞仁
- Organizer
  第9回日本・がん生殖医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 前核期細胞質移植による細胞質機能改善の試み2018
- Author(s)
  藤峯絢子、立花眞仁、久野貴司、東恵子、高橋藍子、田中恵子、井ケ田小緒里、横山絵美、志賀尚美、渡邉善、八重樫伸生
- Organizer
  第56回東北生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] ミトコンドリア遺伝病伝搬防止への取り組み～配偶子系列遺伝子治療の幕開け～2018
- Author(s)
  立花眞仁
- Organizer
  第59回日本卵子学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 発生工学がつなぐ生殖医療と再生医療2018
- Author(s)
  立花眞仁
- Organizer
  第63回日本生殖医学会学術講演会
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 配偶子系列遺伝子治療の展望～胚で診断、胚で治す時代は近い？2018
- Author(s)
  立花眞仁
- Organizer
  生殖医療技術者のためのリカレントセミナー：仙台セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] ミトコンドリア遺伝病に対する核移植を用いた遺伝子治療の試み2017
- Author(s)
  立花眞仁
- Organizer
  第９回新生児科指導医教育セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 成熟卵紡錘体置換（MST）法を用いた配偶子系列遺伝子治療確立へ向けて2017
- Author(s)
  立花眞仁
- Organizer
  第69回日本産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] ミトコンドリアとPGD/PGS2017
- Author(s)
  立花眞仁
- Organizer
  第一回ブラウンテクノロジーズセミナー　ART新技術をめぐる展望と課題　PGD/PGSの海外最新知見を考える
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468
[Presentation] 生殖医療とミトコンドリア2017
- Author(s)
  立花眞仁
- Organizer
  第３１回平成不妊研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05468

1. Shiga Naomi (20595558)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
2. 渡邉善 (40722567)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. IHARA Motomasa (50403506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Suzuki Kichiya (30422116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. Sugawara Atsushi (00554403)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 宇都宮裕貴 (10359507)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 久野貴司 (40897881)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 坂本雅弘 (50645299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋藍子 (30436125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 黒澤大樹 (20770192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 阿部高明 (80292209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 香川慶輝 (30728887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 黒木陽子 (10344037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 勝岡史城 (30447255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 田高周 (60815463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 栗山進一 (90361071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 長崎正朗 (90396862)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 菅原準一 (60280880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tachibana Masahito 立花 眞仁

TACHIBANA Masahito 立花 眞仁

Research Projects

Research Products

Co-Researchers

Challenge towards creation of oocyte via parthenogenetically replicated female genome (PRFG)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploratory Study on Genomic Abnormalities Associated with Assisted Reproductive Technologies in a Three-Generation Cohort

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

大規模出生コホートから月経関連症状の長期的変化を捉える

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of utilization of MRT technique in assisted reproduction on cancer survivorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study of overcoming severe infertility using novel indole acid compound, MA-5

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Preparation and Application of Y chromosome Panel using BirThree Cohort Men

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Challenge of overcoming recurrent IVF failure due to cytoplasmic dysfunction by MST: To secure safety in future generationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of nucleolus function and sumoylation in oocyte

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomics analysis of semen obtained from male infertile patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Clinical Bioenergetics 1st Edition（chapter 16）2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Association of fish intake with menstrual pain: A cross-sectional study of the Japan Environment and Children’s Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial replacement therapy and assisted reproductive technology: A paradigm shift toward treatment of genetic diseases in gametes or in early embryos2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 核移植（ミトコンドリア移植）と研究倫理2017

Author(s)

Journal Title

Data Source

[Journal Article] 成熟卵紡錘体置換（MST）方を用いた配偶子系列遺伝子治療確立へ向けて2017

Tachibana Masahito 立花眞仁

TACHIBANA Masahito 立花眞仁

[Presentation] 魚の摂取頻度と月経痛の有病率の長期的検討　エコチル調査における宮城ユニットセンター追加調査2022