Kimura Noriyuki 木村成志

… Alternative Names

KIMURA Noriyuki 木村成志

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Researcher Number	30433048
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 大分大学, 医学部, 准教授 2015 – 2023: 大分大学, 医学部, 准教授 2007 – 2014: Oita University, Faculty of Medicine, Department of Brain and Nerve Science (Internal Medicine 3), M.D. Assistant Professor 2006: 大分大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine(including psychosomatic medicine) Except Principal Investigator Neurology / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator アルツハイマー病 / アミロイドPET / Neurovascular unit / MRI / 大脳白質病変 / 大脳白質変性 / PET / バイオマーカー / 軽度認知障害 / 先端画像検 … More / 血液・脳脊髄液バイオマーカー / 神経炎症 / 健常高齢者 / Neuro-vascular unit / 無症候性白質病変 / 炎症性サイトカイン / 脳糖代謝量 / 脳内アミロイド蓄積 / 全身性慢性炎症 / Neurovascular Unit / neurovascular unit / 血管危険因子 / 認知症予防 / TIMP / MMP / 血液脳関門障害 / Biomarker / Blood-brain barrier / FDG-PET / PIB-PET / MCI / Alzheimer’s disease / 神経心理検査 / アミロイドイメージング / 認知症 … More Except Principal Investigator GNE / リソソーム / rimmed vacuoles / 遠位型ミオパチー / ubiquitin-proteasome / lysosome / オートファジー / バイオマーカー / 軽度認知障害 / 皮神経 / 末梢神経障害 / 小径線維ニューロパチー / 認知症 / 大脳白質変性 / 炎症性サイトカイン / 脳血液関門障害マーカー / アルツハイマー病 / 睡眠時間 / autophagy / mutant GNE cell / chloroguine / distal mvopathv / 抗GNE抗体 / 変異遺伝子導入細胞 / オートファジー関連遺伝子 / クロロキン・ミオパチー / 遺伝子導入細胞 / クロロキン / valosin/p97 / プロテアゾーム / 小胞体ストレス / プロテアソーム / 縁取り空胞 / 神経分子病態学 / MuRF-1 / atrogin-1 / IGF-1 / nNOS / マイクロアレイ / ユビキチン・プロテアゾーム Less

慢性炎症やNVU障害によるglymphatic system機能低下を介した脳内Aβ蓄積機構の解明Principal Investigator
- Principal Investigator
  
  木村成志
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
Establishment of differential diagnosis and optimal treatment of dementia focusing on peripheral neuropathy
- Principal Investigator
  
  増田曜章
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
Elucidation of pathological progression mechanism based on NVU dysfunction and neuroinflammation in Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  木村成志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
Elucidation of the pathological mechanism by which long-term sleep causes brain dysfunction
- Principal Investigator
  
  花岡拓哉
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
Clarifying pathophysiology of Alzheimer's disease based on systemic chronic inflammation and neurovascular unit dysfunctionPrincipal Investigator
- Principal Investigator
  
  Kimura Noriyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
The role of neurovascular unit in pathogenesis of Alzheimer's diseasePrincipal Investigator
- Principal Investigator
  
  Kimura Noriyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Oita University
The role of white matter lesions in the pathophysiology of ADPrincipal Investigator
- Principal Investigator
  
  KIMURA NORIYUKI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Oita University
distal myopathy with abnormal GNE gene
- Principal Investigator
  
  KUMAMOTO Toshihide
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Kyushu University of Nursing and Social Welfare
  Oita University
Treatment of distal myopathy caused by GNE gene aberration
- Principal Investigator
  
  KUMAMOTO Toshihide
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Oita University
Pathomechanism and treatment of distal myopathy with rimmed vacuoles and GNE gene aberration
- Principal Investigator
  
  KUMAMOTO Toshihide
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Oita University

[Book] サルコードーシス診療の手引き20232023
- Author(s)
  木村成志.
- Total Pages
  4
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-22K07474
[Book] 軽度認知障害(MCI)診療マニュアル2023
- Author(s)
  木村成志
- Total Pages
  20
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22K07474
[Book] Brain Nursing2020
- Author(s)
  木村成志
- Publisher
  メディカ出版
- ISBN
  9784840469586
- Data Source
  KAKENHI-PROJECT-19K07916
[Book] 認知症疾患診療ガイドライン20172017
- Author(s)
  木村成志、松原悦朗
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-16K09248
[Book] ポケット版神経内科検査・処置マニュアル2016
- Author(s)
  木村成志、松原悦朗
- Total Pages
  280
- Publisher
  新興医学出版社
- Data Source
  KAKENHI-PROJECT-25460905
[Book] Bio Clinica2016
- Author(s)
  木村成志、松原悦朗
- Total Pages
  116
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-25460905
[Book] 神経内科 clinical questions and pearls2016
- Author(s)
  木村成志
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-25460905
[Book] Brain Nursing.2014
- Author(s)
  木村成志, 松原悦朗．
- Publisher
  メディカ出版
- Data Source
  KAKENHI-PROJECT-25460905
[Book] 内科医のための認知症診療はじめの一歩．2014
- Author(s)
  木村成志．
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] X-linked Myotubular Myopathy Manifesting Carrier with Central and Peripheral Nervous System Involvement2024
- Author(s)
  Yosuke Takeuch、Teruaki Masuda、Noriyuki Kimura、Kaori Sumi、Mika Jikumaru、Nobuyuki Eura、Ichizo Nishino、Etsuro Matsubara
- Journal Title
  
  Internal Medicine
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06911
[Journal Article] Status epilepticus with unilateral brain edema in COVID-192024
- Author(s)
  Yasuhiro Aso、Teruaki Masuda、Noriyuki Kimura、Etsuro Matsubara
- Journal Title
  
  Internal Medicine
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06911
[Journal Article] Objectively measured prolonged sleep is associated with plasma cytokines in older adults with mild cognitive impairment2024
- Author(s)
  Tokunaga Akari、Kimura Noriyuki、Masuda Teruaki、Hanaoka Takuya、Matsubara Etsuro
- Journal Title
  
  Journal of Sleep Research
  
  Volume: ー Issue: 5
- DOI
  10.1111/jsr.14135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07401, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-23K06911
[Journal Article] Cerebrospinal fluid B-cell activating factor levels as a novel biomarker in patients with neurosarcoidosis2023
- Author(s)
  Sumi K, Masuda T, Kimura N, Akiyoshi Y, Obayashi K, Matsubara E
- Journal Title
  
  J Neurol Sci
  
  Volume: 449 Pages: 120668-120668
- DOI
  10.1016/j.jns.2023.120668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07341, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-23K06911
[Journal Article] Lifestyle factors that affect cognitive function?a longitudinal objective analysis2023
- Author(s)
  Kimura Noriyuki、Sasaki Yuuki、Masuda Teruaki、Ataka Takuya、Eguchi Atsuko、Kakuma Tatsuyuki、Matsubara Etsuro
- Journal Title
  
  Frontiers in Public Health
  
  Volume: 11 Pages: 1215419-1215419
- DOI
  10.3389/fpubh.2023.1215419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19510, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-23K06911
[Journal Article] Predicting positron emission tomography brain amyloid positivity using interpretable machine learning models with wearable sensor data and lifestyle factors2023
- Author(s)
  Kimura Noriyuki、Aota Tomoki、Aso Yasuhiro、Yabuuchi Kenichi、Sasaki Kotaro、Masuda Teruaki、Eguchi Atsuko、Maeda Yoshitaka、Aoshima Ken、Matsubara Etsuro
- Journal Title
  
  Alzheimer's Research & Therapy
  
  Volume: 15 Issue: 1 Pages: 212-212
- DOI
  10.1186/s13195-023-01363-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19510, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-22K07518, KAKENHI-PROJECT-23K06911
[Journal Article] Objective sleep was longitudinally associated with brain amyloid burden in mild cognitive impairment2023
- Author(s)
  Kimura Noriyuki、Sasaki Yuuki、Masuda Teruaki、Ataka Takuya、Eguchi Atsuko、Kakuma Tatsuyuki、Matsubara Etsuro
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 10 Issue: 12 Pages: 2266-2275
- DOI
  10.1002/acn3.51912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19510, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-23K06911
[Journal Article] A Case of Miller Fisher Syndrome with Cerebellar Hypoperfusion2023
- Author(s)
  Sumi Kaori、Kimura Noriyuki、Watanabe Yuko、Yabuuchi Kenichi、Matsubara Etsuro
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 260 Issue: 1 Pages: 47-50
- DOI
  10.1620/tjem.2023.J019
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07474
[Journal Article] Comparison of Brain Amyloid Deposition and Cortical Glucose Metabolism Between Clinic- and Community-Based Cohort2023
- Author(s)
  Yabuuchi Kenichi、Kimura Noriyuki、Masuda Teruaki、Matsubara Etsuro
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 95 Issue: 1 Pages: 299-306
- DOI
  10.3233/jad-230550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19510, KAKENHI-PROJECT-22K07474, KAKENHI-PROJECT-22K07518, KAKENHI-PROJECT-23K06911
[Journal Article] Cerebrospinal Fluid Interleukin-6 in Immune Checkpoint Inhibitor-Induced Autoimmune Meningoencephalitis2022
- Author(s)
  Mizukami Takeshi、Masuda Teruaki、Kimura Noriyuki、Uchida Hirotatsu、Jikumaru Mika、Hanaoka Takuya、Matsubara Etsuro
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 258 Issue: 2 Pages: 159-165
- DOI
  10.1620/tjem.2022.J071
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07905, KAKENHI-PROJECT-22K07474
[Journal Article] Association of serum thyroid hormone levels with <scp>positron emission tomography</scp> imaging in non‐demented older adults2022
- Author(s)
  Goto Megumi、Kimura Noriyuki、Matsubara Etsuro
- Journal Title
  
  Psychogeriatrics
  
  Volume: 22 Issue: 3 Pages: 373-381
- DOI
  10.1111/psyg.12825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] Changes in objectively measured lifestyle factors during the COVID-19 pandemic in community-dwelling older adults2022
- Author(s)
  Ataka Takuya、Kimura Noriyuki、Eguchi Atsuko、Matsubara Etsuro
- Journal Title
  
  BMC Geriatrics
  
  Volume: 22 Issue: 1 Pages: 326-326
- DOI
  10.1186/s12877-022-03043-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-22K07474
[Journal Article] Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis2022
- Author(s)
  Sadequl Islam, Yang Sun, Yuan Gao, Tomohisa Nakamura, Arshad Ali Noorani, Tong Li, Philip C Wong, Noriyuki Kimura, Etsuro Matsubara, Kensaku Kasuga, Takeshi Ikeuchi, Taisuke Tomita, Kun Zou, Makoto Michikawa
- Journal Title
  
  J Neurosci
  
  Volume: 42 Issue: 8 Pages: 1574-1586
- DOI
  10.1523/jneurosci.2039-21.2021
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07846, KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19H01015
[Journal Article] Temporal Changes in Brain Perfusion in Neuronal Intranuclear Inclusion Disease2021
- Author(s)
  Ataka T, Kimura N, Matsubara E.
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 6 Pages: 941-944
- DOI
  10.2169/internalmedicine.5743-20
- NAID
  130007998450
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-03-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] Relationship between Cerebrospinal Fluid Matrix Metalloproteinases Levels and Brain Amyloid Deposition in Mild Cognitive Impairment2021
- Author(s)
  Sasaki Yuuki、Kimura Noriyuki、Aso Yasuhiro、Yabuuchi Kenichi、Aikawa Miki、Matsubara Etsuro
- Journal Title
  
  Biomolecules
  
  Volume: 11 Issue: 10 Pages: 1496-1496
- DOI
  10.3390/biom11101496
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K07998, KAKENHI-PROJECT-19H03566
[Journal Article] Novel Serum Biomarkers of Neurovascular Unit Associated with Cortical Amyloid Deposition2021
- Author(s)
  Aso Yasuhiro、Kimura Noriyuki、Matsubara Etsuro
- Journal Title
  
  Journal of Alzheimer's Disease
  
  Volume: 84 Issue: 2 Pages: 905-914
- DOI
  10.3233/jad-215135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19H03566
[Journal Article] 【認知症-超高齢社会、現在、未来へのさまざまな課題】認知症の日常診療に必要な具体的知識とその活用　アルツハイマー型認知症の血液バイオマーカー開発の現状2021
- Author(s)
  木村成志
- Journal Title
  
  Medical Practice
  
  Volume: 38 Pages: 1207-1210
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] Association between Matrix Metalloproteinases, Their Tissue Inhibitor and White Matter Lesions in Mild Cognitive Impairment.2020
- Author(s)
  Kimura N, Aikawa M, Etou K, Aso Y, Matsubara E.
- Journal Title
  
  Curr Alzheimer Res.
  
  Volume: 17(6) Issue: 6 Pages: 547-555
- DOI
  10.2174/1567205017666200810171322
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19H03566
[Journal Article] Association of Cerebrospinal Fluid Adiponectin Levels With Cerebral Glucose Metabolism In Mild Cognitive Impairment: A Pilot Study.2020
- Author(s)
  Ataka T, Kimura N, Mizukami T, Uchida H, Matsubara E.
- Journal Title
  
  Curr Alzheimer Res.
  
  Volume: 17(12) Issue: 12 Pages: 1126-1132
- DOI
  10.2174/1567205017666201109150358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19H03566
[Journal Article] Association of Modifiable Lifestyle Factors With Cortical Amyloid Burden and Cerebral Glucose Metabolism in Older Adults With Mild Cognitive Impairment.2020
- Author(s)
  Kimura N, Aso Y, Yabuuchi K, Ishibashi M, Hori D, Sasaki Y, Nakamichi A, Uesugi S, Jikumaru M, Sumi K, Eguchi A, Obara H, Kakuma T, Matsubara E.
- Journal Title
  
  JAMA Netw Open.
  
  Volume: 3(6):e205719. Issue: 6 Pages: e205719-e205719
- DOI
  10.1001/jamanetworkopen.2020.5719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K07998, KAKENHI-PROJECT-19H03566
[Journal Article] Association between objectively measured walking steps and sleep in community-dwelling older adults: A prospective cohort study.2020
- Author(s)
  Kimura N, Aso Y, Yabuuchi K, Matsubara E.
- Journal Title
  
  PLoS One.
  
  Volume: 14;15(12) Issue: 12 Pages: e0243910-e0243910
- DOI
  10.1371/journal.pone.0243910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K07998, KAKENHI-PROJECT-19H03566
[Journal Article] 運動と認知症2020
- Author(s)
  木村成志
- Journal Title
  
  最新精神医学
  
  Volume: 25(5) Pages: 383-391
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] A case of myelin oligodendrocyte glycoprotein-antibody-associated disease presenting with tumefactive demyelinating lesion.2020
- Author(s)
  Ataka T, Kimura N, Matsubara E.
- Journal Title
  
  Mult Scler Relat Disord.
  
  Volume: 43:102191. Pages: 102191-102191
- DOI
  10.1016/j.msard.2020.102191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] A New Serum Biomarker Set to Detect Mild Cognitive Impairment and Alzheimer's Disease by Peptidome Technology.2020
- Author(s)
  Abe K, Shang J, Shi X, Yamashita T, Hishikawa N, Takemoto M, Morihara R, Nakano Y, Ohta Y, Deguchi K, Ikeda M, Ikeda Y, Okamoto K, Shoji M, Takatama M, Kojo M, Kuroda T, Ono K, Kimura N, Matsubara E, Osakada Y, Wakutani Y, Takao Y, Higashi Y, Asada K, Senga T, Lee LJ, Tanaka K
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 73(1) Issue: 1 Pages: 217-227
- DOI
  10.3233/jad-191016
- NAID
  120006949464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07385, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K07965, KAKENHI-PROJECT-17H04196, KAKENHI-PROJECT-19H03566
[Journal Article] Flotillin is a Novel Diagnostic Blood Marker of Alzheimer's Disease.2019
- Author(s)
  Abdullah M, Kimura N, Akatsu H, Hashizume Y, Ferdous T, Tachita T, Iida S, Zou K, Matsubara E, Michikawa M.
- Journal Title
  
  J Alzheimers Dis.
  
  Volume: 72 Issue: 4 Pages: 1165-1176
- DOI
  10.3233/jad-190908
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07916, KAKENHI-PROJECT-19K17040, KAKENHI-PROJECT-19H03566, KAKENHI-PROJECT-17K08725, KAKENHI-PROJECT-16H06277
[Journal Article] Diagnosis of mild cognitive impairment using multiple neuroimaging modalities in addition to the Mini-Mental State Examination.2019
- Author(s)
  Kaneko H, Kimura N, Nojima S, Abe K, Aso Y, Matsubara E.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 19 Pages: 1193-1197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07916
[Journal Article] Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study2019
- Author(s)
  Noriyuki Kimura, Yasuhiro Aso, Kenichi Yabuuchi, Masato Ishibashi, Daiji Hori, Yuuki Sasaki, Atsuhito Nakamichi, Souhei Uesugi, Hideyasu Fujioka, Shintaro Iwao, Mika Jikumaru, Tetsuji Katayama, Kaori Sumi, Atsuko Eguchi, Satoshi Nonaka, Masakazu Kakumu, Etsuro Matsubara
- Journal Title
  
  Frontier in Neurology
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] Comparison of brain perfusion patterns in dementia with Lewy bodies patients with or without cingulate island sign.2019
- Author(s)
  Ishibashi M, Kimura N, Sumi K, Aso Y, Matsubara E.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: 19 Issue: 3 Pages: 197-202
- DOI
  10.1111/ggi.13586
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05228, KAKENHI-PROJECT-16K09248
[Journal Article] 辺縁系症状を呈した脳炎・脳症のSPECT所見の検討2018
- Author(s)
  中道淳仁, 木村成志, 石橋正人, 薮内健一, 麻生泰弘, 松原悦朗
- Journal Title
  
  NEUROINFECTION
  
  Volume: 23 Pages: 140-145
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] Effects of white matter lesions on brain perfusion in patients with mild cognitive impairment.2018
- Author(s)
  Ishibashi M, Kimura N, Aso Y, Matsubara E
- Journal Title
  
  Clin Neurol Neurosurg.
  
  Volume: 168 Pages: 7-11
- DOI
  10.1016/j.clineuro.2018.02.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09248, KAKENHI-PROJECT-16H05228
[Journal Article] アルツハイマー病の発症を予測する血漿バイオマーカーの候補(解説/特集)2017
- Author(s)
  木村成志
- Journal Title
  
  Dementia Japan
  
  Volume: 31 Pages: 67-78
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] 認知症と間違われやすい病態　Treatable dementiaを見逃さない2017
- Author(s)
  木村成志
- Journal Title
  
  日本早期認知症学会誌
  
  Volume: 10 Pages: 57-63
- NAID
  40021505829
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] The evaluation of brain perfusion SPECT using an easy Z-score imaging system in the mild cognitive impairment subjects with brain amyloid-β deposition.2017
- Author(s)
  Takemaru M, Kimura N, Abe Y, Goto M, Matsubara E
- Journal Title
  
  Clin Neurol Neurosurg.
  
  Volume: 160 Pages: 111-115
- DOI
  10.1016/j.clineuro.2017.06.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] Brain perfusion in corticobasal syndrome with progressive aphasia2016
- Author(s)
  Yoshitake Abe, Noriyuki Kimura, Megumi Goto, Yasuhiro Aso, Etsuro Matsubara.
- Journal Title
  
  Dement Geriatr Cogn Dis Extra.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] アルツハイマー病の病態における無症候性白質病変の意義.2016
- Author(s)
  木村成志，松原悦朗
- Journal Title
  
  細胞
  
  Volume: 48 Pages: 25-30
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] アルツハイマー病の無症候性白質病変が脳機能および臨床症状に及ぼす影響.2016
- Author(s)
  木村成志，松原悦朗
- Journal Title
  
  BIO Clinica.
  
  Volume: 31 Pages: 93-99
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] Brain Perfusion in Corticobasal Syndrome with Progressive Aphasia2016
- Author(s)
  Abe Y, Kimura N, Goto M, Aso Y, Matsubara E
- Journal Title
  
  Dement Geriatr Cogn Dis Extra
  
  Volume: 6 Issue: 1 Pages: 133-141
- DOI
  10.1159/000443329
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05228, KAKENHI-PROJECT-16K09248
[Journal Article] Brain SPECT Findings at the Acute Stage of Disease in Patients with Wernicke Encephalopathy.2016
- Author(s)
  Abe Y, Kimura N, Goto M, Aso Y, Matsubara E.
- Journal Title
  
  J Gerontol Geriatr Res
  
  Volume: 5 Pages: 357-357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09248
[Journal Article] Evaluation of regional cerebral blood flow in Alzheimer's disease patients with subclinical hypothyroidism.2015
- Author(s)
  Haji M, Kimura N, Hanaoka T, Aso Y, Takemaru M, Hirano T, Matsubara E.
- Journal Title
  
  Dement Geriatr Cogn Disord.
  
  Volume: 39 Issue: 5-6 Pages: 360-367
- DOI
  10.1159/000375298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] Relationship between white matter lesions and regional cerebral blood flow changes during longitudinal follow up in Alzheimer's disease.2015
- Author(s)
  Hanaoka T, Kimura N, Aso Y, Takemaru M, Kimura Y, Ishibashi M, Matsubara E.
- Journal Title
  
  Geriatr Gerontol Int.
  
  Volume: - Issue: 7 Pages: 836-842
- DOI
  10.1111/ggi.12563
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460905, KAKENHI-PROJECT-16H05228, KAKENHI-PROJECT-16K09248, KAKENHI-PROJECT-16K15483
[Journal Article] Creutzfeldt-Jakob disease with a prion protein gene codon 180 mutation presenting striking asymmetric abnormalities on magnetic resonance imaging.2015
- Author(s)
  Amano Y, Kimura N, Hanaoka T, Aso Y, Takemaru M, Hirano T, Murai H, Satoh K, Matsubara E.
- Journal Title
  
  Prion.
  
  Volume: Mar 2:0.
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] Creutzfeldt-Jakob Disease with a prion protein gene codon 180 mutation presenting asymmetric cortical high-intensity on magnetic resonance imaging.2015
- Author(s)
  Amano Y, Kimura N, Hanaoka T, Aso Y, Hirano T, Murai H, Satoh K, Matsubara E.
- Journal Title
  
  Prion
  
  Volume: 9 Pages: 29-33
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] Brain perfusion SPECT in limbic encephalitis associated with autoantibody against the glutamate receptor epsilon 22014
- Author(s)
  Kimura N, Kumamoto T, Takahashi Y
- Journal Title
  
  Clin Neurol Neurosurg
  
  Volume: 118 Pages: 44-48
- DOI
  10.1016/j.clineuro.2013.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591251, KAKENHI-PROJECT-24591537
[Journal Article] Brain perfusion SPECT in limbic encephalitis associated with autoantibody against the glutamate receptor epsilon 2.2014
- Author(s)
  Kimura N, Kumamoto T, Takahashi Y.
- Journal Title
  
  Clin Neurol Neurosurg.
  
  Volume: 11 Pages: 44-48
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] Relationship between White Matter Lesions and Progression of Cognitive Decline in Alzheimer's Disease.2013
- Author(s)
  Kimura N, Nakama H, Nakamura K, Aso Y, Kumamoto T.
- Journal Title
  
  Dement Geriatr Cogn Dis Extra.
  
  Volume: 29 Issue: 1 Pages: 96-101
- DOI
  10.1159/000350317
- Data Source
  KAKENHI-PROJECT-25460905
[Journal Article] Role of ubiquitin-proteasome proteolysis in musclefiber destruction in experimental chloroquine-inducedmyopathy2009
- Author(s)
  Kimura N
- Journal Title
  
  Muscle Nerve 39(4)
  
  Pages: 521-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591005
[Journal Article] Role of ubiquitin-proteasome proteolysis in muscle fiber destruction in experimental chloroquine-induced myopathy2009
- Author(s)
  Kimura N, Kumamoto T, Oniki T, Nomura M, Nakamura K, Abe Y, Hazama Y, Ueyama H
- Journal Title
  
  Muscle Nerve 39(4)
  
  Pages: 521-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591005
[Journal Article] Role of ubiquitin-proteasome proteolysis in muscle fiber destruc-tion in experimental chloroquine-induced myopathy2009
- Author(s)
  Kimura N, Kumamoto T, Oniki T, Nomura M, Nakamura K, Abe Y, Hazama Y, Ueyama H
- Journal Title
  
  Muscle Nerve 39(4)
  
  Pages: 521-528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591005
[Journal Article] Expression of autophagy-associated genes in skeletal muscle: an experi mental model of chloroquine-induced myopathy2007
- Author(s)
  Kimura N
- Journal Title
  
  Pathobiology 74
  
  Pages: 169-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590952
[Journal Article] Role of proteasomes in the formation of neurofilamentous inclusions in spinal motor neurons of aluminum-treated rabbits2007
- Author(s)
  Kimura N
- Journal Title
  
  Neuropathology 27
  
  Pages: 522-530
- NAID
  10021236845
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590952
[Journal Article] Expression of autophagy-associated genes in skeletal muscle:an experimental model of chloroquine-induced myopathy2007
- Author(s)
  Kimura N
- Journal Title
  
  Pathobiology 74
  
  Pages: 169-176
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590952
[Journal Article] Role of proteasomes in the formation of neurofilamentous inclusions in spinal motorneurons of aluminum-treated rabbits2007
- Author(s)
  Kimura, N., Kumamoto, T., Ueyama, H., Horinouchi, H., Ohama, E
- Journal Title
  
  Neuropathology 27(6)
  
  Pages: 522-530
- NAID
  10021236845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590952
[Journal Article] Expression of autophagy-associated genes in skeletal muscle : an experimental model of chloroquine-induced myopathy2007
- Author(s)
  Kimura, N., Kumamoto, T., Kawamura, Y., Himeno, T., Nakamura, K., Ueyama, H., Arakawa, R
- Journal Title
  
  Pathobiology 74(3)
  
  Pages: 169-176
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590952
[Journal Article] Progressive multifocal leukoencephalopathy in an HTLV-I carrier2006
- Author(s)
  Kimura A, Ueyama H, Kimura N, Fujimoto S, Kumamoto T
- Journal Title
  
  Clin Neurol Neurosurg 108(8)
  
  Pages: 768-771
- Data Source
  KAKENHI-PROJECT-18590952
[Presentation] Clinical performance evaluation of plasma amyloid-βbiomarkers in predicting amyloid positivity in community-based mild cognitive impairment cohort2024
- Author(s)
  Noriyuki Kimura, Teruaki Masuda, Tsukasa Takeuchi, Naoki Kaneko, Shinichi Iwamoto, Etsuro Matsubara
- Organizer
  18th International Conference on Alzheimer’s & Parkinson’s Diseases
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] 多彩な臨床症候を呈したミオチュブラーミオパチー manifesting carrierの1例2024
- Author(s)
  竹内陽介、増田曜章、角華織、軸丸美香、江浦信之、西野一三、木村成志、松原悦朗
- Organizer
  第243回日本神経学会九州地方会
- Data Source
  KAKENHI-PROJECT-23K06911
[Presentation] 実臨床における血液バイオマーカーを活用したアルツハイマー病の診断ワークフロー構築2023
- Author(s)
  木村成志
- Organizer
  第12回認知症予防学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] 地域コホートにおける血液バイオマーカーの有用性2023
- Author(s)
  木村成志，増田曜章，伊藤典明，竹内　司，岩本慎一，松原悦朗
- Organizer
  第42回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] Atypical ADのPET・SPECT画像所見2023
- Author(s)
  木村成志，伊藤秀幸，水上健，中道淳仁，藪内健一，増田曜章，松原悦朗
- Organizer
  第13回日本脳血管・認知症学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] 神経サルコイドーシスにおける新規バイオマーカーとしての髄液BAFF値の評価2023
- Author(s)
  角華織、増田曜章、木村成志、秋吉裕子、松原悦朗
- Organizer
  第43回日本サルコイドーシス/肉芽腫性疾患学会総会
- Data Source
  KAKENHI-PROJECT-23K06911
[Presentation] MMSEと複数の画像診断法の組み合わせによる軽度認知障害の診断精度2023
- Author(s)
  木村成志，金子裕美，松原悦朗
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] 軽度認知障害における微小脳出血の検討2023
- Author(s)
  増田曜章、木村成志、松崎布菜、松原悦朗
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06911
[Presentation] Relationship between CSF MMPs levels, brain amyloid deposition, and white matter lesions2022
- Author(s)
  Noriyuki Kimura, Yuuki Sasaki, Yasuhiro Aso, Kenichi Yabuuchi, Miki Aikawa, and Etsuro Matsubara
- Organizer
  The 63rd Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] 生活習慣による認知症予防法の開発2022
- Author(s)
  木村成志, 麻生泰弘, 佐々木雄基, 藪内健一, 松原悦朗
- Organizer
  第119回日本内科学会総会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] ウェアラブル生体センサを用いた運動と睡眠に関する検討2022
- Author(s)
  木村成志　麻生泰弘　松原悦朗
- Organizer
  第11回日本認知症予防学会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] Association between modifiable lifestyle factors and PET imaging in mild cognitive impairment2022
- Author(s)
  Noriyuki Kimura
- Organizer
  The 63rd Annual Meeting of the Japanese Society of Neurology
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] ウェアラブルデバイスを用いた新たな認知症リスク因子の発掘～睡眠の重要性～2022
- Author(s)
  木村成志
- Organizer
  日本睡眠学会第 47回定期学術集会
- Data Source
  KAKENHI-PROJECT-22K07474
[Presentation] ウェアラブル生体センサを用いた地域在住高齢者における認知症リスク因子の発掘2021
- Author(s)
  木村成志
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 認知症とデジタルヘルス　ウェアラブルデバイスを用いた新たな認知症リスク因子の発掘2021
- Author(s)
  木村成志，松原悦朗
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] アミロイドPET・FDG-PET画像と関連する生活習慣因子2021
- Author(s)
  木村成志，麻生康弘，薮内健一，石橋正人，堀　大滋，軸丸美香，松原悦朗
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 認知機能と関連する生活習慣因子2021
- Author(s)
  木村成志，松原悦朗
- Organizer
  第10回認知症予防学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 睡眠時間は脳内アミロイド蓄積および脳機能と関連する2021
- Author(s)
  木村成志，麻生康弘，薮内健一，石橋正人，松原悦朗
- Organizer
  第40回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 運動と睡眠の関連2021
- Author(s)
  木村成志，麻生泰弘，松原悦朗
- Organizer
  第3回日本脳サプリメント学会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] Cingulate island sign(CIS)指標における年齢層別cut-off valueの検討2020
- Author(s)
  内田大達、木村成志、麻生泰弘、石橋正人、軸丸美香、松原悦朗
- Organizer
  第61回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 地域在住高齢者の認知機能と関連する生活習慣因子の探索的研究2020
- Author(s)
  木村成志　麻生康弘　薮内健一　石橋正人　堀　大滋　軸丸美香　松原悦朗
- Organizer
  第61回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 高齢者における認知機能障害と生活習慣因子2020
- Author(s)
  木村成志, 麻生康弘, 薮内健一, 松原悦朗
- Organizer
  第39回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 脳内アミロイド蓄積および脳機能低下予防における睡眠の重要性2020
- Author(s)
  木村成志
- Organizer
  第2回日本脳サプリメント学会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 地域在住高齢者における生活習慣の年齢および性別による影響2019
- Author(s)
  木村成志, 麻生康弘, 薮内健一, 石橋正人, 堀大滋, 軸丸美香, 松原悦朗
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 神経核内封入体病(NIID)の2症例2019
- Author(s)
  堀　大滋　木村成志　松原悦朗
- Organizer
  第60回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] Creutzfeldt-Jakob Disease(CJD)における脳血流SPECT所見の検討2019
- Author(s)
  中道淳仁, 木村成志, 松原悦朗
- Organizer
  第24回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] アディポネクチンとAD病態の関連2019
- Author(s)
  木村成志　麻生康弘　薮内健一　堀　大滋　石橋正人　軸丸美香　松原悦朗
- Organizer
  第60回日本神経学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 軽度認知障害におけるMoCA-JとPET画像の関連2019
- Author(s)
  和田敦子, 木村成志, 麻生康弘, 薮内健一, 石橋正人, 堀大滋, 軸丸美香, 松原悦朗
- Organizer
  第38回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07916
[Presentation] 脳内アミロイド蓄積と認知機能・脳萎縮・脳糖代謝の関連2018
- Author(s)
  木村成志, 佐々木雄基, 藪内健一, 堀大滋, 麻生泰弘, 軸丸美香, 石橋正人, 松原悦朗
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] アミロイドPET陽性の早期認知症に対する薬物療法の効果2018
- Author(s)
  木村成志　松原悦朗
- Organizer
  第８回日本認知症予防学会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 血管危険因子と脳内アミロイド蓄積および脳糖代謝の関連2018
- Author(s)
  中道淳仁, 木村成志, 佐々木雄基, 藪内健一, 堀大慈, 麻生泰弘, 松原悦朗
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 若年性アルツハイマー型認知症と晩発性アルツハイマー型認知症の臨床・画像的比較検討2018
- Author(s)
  角華織, 木村成志, 麻生泰弘, 石橋正人, 軸丸美香, 松原悦朗
- Organizer
  第５９回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 若年性アルツハイマー型認知症と晩発性アルツハイマー型認知症の臨床・画像的比較検討2018
- Author(s)
  堀大滋, 木村成志, 衞藤圭純, 岩尾槙太郎, 角華織, 中道淳仁, 藤岡秀康, 佐々木雄基, 藪内健一, 松原悦朗
- Organizer
  第５９回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 地域在宅高齢者に対する認知症啓発および検診の重要性2018
- Author(s)
  木村成志, 軸丸美香, 麻生泰弘, 堀大滋, 松原悦朗, 藤野孝雄
- Organizer
  第115回日本内科学会総会・講演会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 軽度認知障害における画像バイオマーカーの検討2018
- Author(s)
  木村成志, 佐々木雄基, 堀大滋, 藪内健一, 麻生泰弘, 軸丸美香, 石橋正人, 松原悦朗
- Organizer
  第５９回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Wernicke脳症急性期における99mTc-ECD脳血流SPECT所見の検討2018
- Author(s)
  麻生泰弘, 安部芳武, 木村成志, 佐々木雄基, 堀大滋, 渡部優子, 石橋正人, 藪内健一, 軸丸美香, 松原悦朗
- Organizer
  第37回日本認知症学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] MCI due to ADにおける無症候性白質病変の臨床的意義2018
- Author(s)
  麻生泰弘, 相川未希, 衞藤圭純, 岩尾槙太郎, 角華織, 中道淳仁, 藤岡秀康, 佐々木雄基, 堀大滋, 天野優子, 石橋正人, 木村有希, 藪内健一, 軸丸美香, 木村成志, 松原悦朗
- Organizer
  第５９回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] 脳血流SPECTにより脳内アミロイド沈着の予測は可能か?2017
- Author(s)
  木村有希, 佐々木雄基, 堀大滋, 片山徹二, 麻生泰弘, 仲田崇, 軸丸美香, 花岡拓哉, 木村成志, 松原悦朗
- Organizer
  第114日本内科学会総会・講演会
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Characteristics of patient population of dementia with Lewy bodies (DLB) and Parkinson’s disease with dementia (PDD) exhibiting frontal hypoperfusion in bran perfusion SPECT.2017
- Author(s)
  Yabuuchi K, Kimura N, Miura Y, Matsubara E.
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Relationship between white matter lesions and cognitive function in subjects with mild cognitive impairment.2017
- Author(s)
  Aso Y, Arita Y, Miura S, Iwao K, Sumi K, Nakamichi A, Fujioka K, Sasaki Y, Hori D, Amano Y, Ishibashi M, Yabuuchi L, Abe Y, Jikumaru M, Kimura N, Matsubara E.
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Predicting brain amyloid-β deposition using easy Z-score analysis.2017
- Author(s)
  Kimura N, takemaru M, Aso Y, Hanaoka T, Matsubara E.
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Relationship between cytokine levels in the cerebrospinal fluid and 11C-Pittsburgh compound B retention in patients with mild cognitive impairment.2017
- Author(s)
  Abe Y, Kimura N, Takahashi R, Gotou M, Matsubara E.
- Organizer
  XXIII World Congress of Neurology
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] Treatable dementia(治癒の期待できる認知症)の再考神経内科の立場から　認知症と間違われやすい病態『treatable dementiaを見逃さない』.2016
- Author(s)
  木村成志.
- Organizer
  第17回日本早期認知症学会
- Place of Presentation
  熊本鶴屋ホール（熊本県，熊本市）
- Year and Date
  2016-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] AD発症リスクの解明を目指した臼杵市研究.2016
- Author(s)
  木村成志.
- Organizer
  第57回日本神経学会総会
- Place of Presentation
  神戸コンベンションセンター（兵庫県，神戸市）
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K09248
[Presentation] アミロイド画像施行症例でのplasma biomarker の候補.2015
- Author(s)
  木村成志
- Organizer
  第34回日本認知症学会学術集会.
- Place of Presentation
  リンクステーションホール青森(青森県，青森市)
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 無症候性白質病変がアルツハイマー型認知症（ＡＤ）の脳血流に及ぼす影響2015
- Author(s)
  木村有希、天野優子、石橋正人、竹丸誠、麻生泰弘、花岡拓哉、木村成志、松原悦朗
- Organizer
  第112回日本内科学会総会
- Place of Presentation
  みやこめっせ（京都府，京都）
- Year and Date
  2015-04-10
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] Typical ADとMixed ADの臨床と診断.2015
- Author(s)
  木村成志, 石橋正人, 安部芳武, 佐々木雄基, 松原悦朗.
- Organizer
  第56回日本神経学会学術大会.
- Place of Presentation
  朱鷺メッセ(新潟県，新潟市)
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 地域における認知症早期診断体制の構築2013
- Author(s)
  木村成志
- Organizer
  第32回日本認知症学会学術集会
- Place of Presentation
  キッセイ文化ホール（長野県）
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] アルツハイマー型認知症における無症候性大脳白質病変の臨床的意義2013
- Author(s)
  木村成志
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] GNE結合蛋白の検索2013
- Author(s)
  中村憲一郎、竹丸誠、麻生泰弘、木村成志、平野照之、熊本俊秀
- Organizer
  第54回日本神経学会学術大会
- Place of Presentation
  東京
- Year and Date
  2013-05-30
- Data Source
  KAKENHI-PROJECT-23591251
[Presentation] 慢性潅流モデルラットの脳梁に対する網羅的遺伝子解析と蛋白質局在の検討2013
- Author(s)
  麻生泰弘、竹丸　誠、中村憲一郎、木村成志、平野照之、藤木　稔、熊本俊
- Organizer
  日本神経学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-23591251
[Presentation] GNE結合蛋白の検索2013
- Author(s)
  中村憲一郎、竹丸　誠、麻生泰弘、木村成志、平野照之、熊本俊秀
- Organizer
  日本神経学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-23591251
[Presentation] Role of ubiquitin-proteasome proteolysis in muscle fiber destruction in experimental chloroquine-induced myopathy.2010
- Author(s)
  Kumamoto T, Kimura N, Oniki T, Nomura M, Nakamura K, Abe Y, Hazama Y, Ueyama H
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] Expression of VCP in (muscle fibers of) experimental chloroquine-induced myopathy.2010
- Author(s)
  Aso Y, Sawada K, Masuda T, Hazama Y, Nakamura K, Kimura N, Kumamoto T
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples.
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] Expression of VCP in (muscle fibers of) experimental chloroquine-induced myopathy.2010
- Author(s)
  Aso Y, Sawada K, Masuda T, Hazama Y, Nakamura K, Kimura N, Kumamoto T
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] 神経・筋サルコイドーシスの診断基準の評価と今後の課題2010
- Author(s)
  熊本俊秀、増田曜章、岡崎敏郎、花岡拓哉、荒川竜樹、迫祐介、木村成志
- Organizer
  第51回日本神経学会総会
- Place of Presentation
  東京
- Year and Date
  2010-05-16
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] サルコイドーシスの経過中に四肢筋力低下、筋萎縮を認め、慢性ミオパチー型筋サルコイドーシスと考えられた1例2010
- Author(s)
  竹丸誠、岡崎敏郎、近澤亮、薮内健一、花岡拓哉、中村憲一郎、荒川竜樹、木村成志、熊本俊秀
- Organizer
  第30回日本サルコイドーシス/肉芽腫性疾患学会総会
- Place of Presentation
  浜松
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] Role of ubiquitin-proteasome proteolysis in muscle fiber destruc-tion in experimental chloroquine-induced myopathy.2010
- Author(s)
  Kumamoto T, Kimura N, Oniki T, Nomura M, Nakamura K, Abe Y, Hazama Y, Ueyama H
- Organizer
  12th International Congress on Neuromuscular Diseases
- Place of Presentation
  Naples.
- Year and Date
  2010-07-18
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] 空胞形成ミオパチーの筋崩壊における-酸化窒素合成酵素と酸化ストレスの動態2009
- Author(s)
  増田曜章、兒玉憲人、新川雄高、迫祐介、中村憲一郎、木村成志、熊本俊秀
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] ALSの脊髄前角運動ニューロンにおけるpNFの蓄積および細胞変性へのユビキチン・プロテアゾーム系の関与2009
- Author(s)
  木村成志、野村有希、増田曜章、岡崎敏郎、迫祐介、花岡拓哉、中村憲一郎、荒川竜樹、熊本俊秀
- Organizer
  第50回日本神経病理学会学術研究会
- Place of Presentation
  高松
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] 空胞形成ミオパチーの筋崩壊における一酸化窒素合成酵素と酸化ストレスの動態2009
- Author(s)
  増田曜章、兒玉憲人、新川雄高、迫祐介、中村憲一郎、木村成志、熊本俊秀
- Organizer
  第50回日本神経学会総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] IGFによるrimmed vacuolar myopathyの治療の試み2008
- Author(s)
  迫祐介、高柳義和、安部芳武、中村憲一郎、木村成志、熊本俊秀
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-20591005
[Presentation] IGF-1 and rimmed vacuolar myopathy2007
- Author(s)
  Hazaraa, Y., Kozai, Y., Nakamura, K., Kimura, N., Kumamoto, T
- Organizer
  47th Annual Meeting of Japanese Society of Neurology
- Place of Presentation
  Nagoya
- Year and Date
  2007-05-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590952
[Presentation] :神経サルコイドーシスに伴う水頭症に対しステロイド治療は効果不十分でシャント術が奏効した1例．
- Author(s)
  石橋正人, 藤岡秀康, 佐々木雄基, 天野優子, 木村有希, 竹丸誠, 麻生泰弘, 花岡拓哉, 木村成志, 平野照之, 松原悦朗, 札場博貴, 武田裕, 内田晋, 上田徹, 藤木稔．
- Organizer
  第32回日本神経治療学会総会．
- Place of Presentation
  東京都文京区　東京ドームホテル
- Year and Date
  2014-11-20 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 筋萎縮性側索硬化症における神経症候と予後の関係．
- Author(s)
  中村憲一郎, 佐々木雄基, 天野優子, 木村有希, 石橋正人, 近澤亮, 藪内健一, 竹丸　誠, 麻生泰弘, 木村成志, 平野照之, 松原悦朗．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 確定診断に2度の脳生検を要した頭蓋内悪性腫瘍の臨床的検討．
- Author(s)
  麻生泰弘, 佐々木雄基, 堀　大滋, 天野優子, 石橋正人, 木村有希, 近澤亮, 藪内健一,木村成志, 平野照之, 松原悦朗．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] Corticobasal syndromeの言語機能に関する臨床画像検討．
- Author(s)
  佐々木雄基, 木村成志, 石橋正人, 堀　大滋, 天野優子, 近澤亮, 木村有希, 藪内健一, 麻生泰弘, 平野照之, 松原悦朗, 有須梨乃, 渡辺香織, 松浦祐也, 片岡晶志．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 大分県臼杵市における認知症ネットワーク構築．
- Author(s)
  木村成志.
- Organizer
  第4回日本認知症予防学会学術集会．
- Place of Presentation
  東京都江戸川区　タワーホール船堀
- Year and Date
  2014-09-26 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] Aβオリゴマー抗体は神経細胞内外でAβオリゴマーを無毒化している．
- Author(s)
  竹丸　誠, 佐々木雄基, 天野優子, 木村有希, 近澤亮, 石橋正人, 藪内健一,麻生泰弘, 中村憲一郎, 木村成志, 平野照之, 松原悦朗．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 進行性核上性麻痺における認知機能障害と脳血流の関連
- Author(s)
  木村成志, 佐々木雄基, 天野優子, 石橋正人, 木村有希, 近澤亮, 藪内健一, 竹丸　誠, 麻生泰弘, 中村憲一郎, 平野照之, 松原悦朗．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905
[Presentation] 抗NMDA受容体脳炎4例の検討．
- Author(s)
  藪内健一, 佐々木雄基, 天野優子,石橋正人, 木村有希, 近澤亮, 竹丸　誠, 麻生泰弘, 中村憲一郎, 木村成志, 平野照之, 松原悦朗．
- Organizer
  第55回日本神経学会学術大会．
- Place of Presentation
  福岡県福岡市　福岡国際会議場
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25460905

1. HANAOKA Takuya (40433057)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. KUMAMOTO Toshihide (40134936)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
3. NAKAMURA Kenichiro (70608372)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
4. Aso Yasuhiro (80555194)

# of Collaborated Projects: 3 results

# of Collaborated Products: 43 results
5. OKAZAKI Toshio (00464438)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. ARAKAWA Ryuki (90363548)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. MASUDA Teruaki (50464459)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. HAZAMA Yusuke (80448547)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. 松原悦朗 (70219468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
10. 大林光念 (90361899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. ZOU Kun

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 東海林幹夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Noriyuki 木村 成志

KIMURA Noriyuki 木村 成志

Research Projects

Research Products

Co-Researchers

慢性炎症やNVU障害によるglymphatic system機能低下を介した脳内Aβ蓄積機構の解明Principal Investigator

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Establishment of differential diagnosis and optimal treatment of dementia focusing on peripheral neuropathy

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Elucidation of pathological progression mechanism based on NVU dysfunction and neuroinflammation in Alzheimer's diseasePrincipal Investigator

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Elucidation of the pathological mechanism by which long-term sleep causes brain dysfunction

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Clarifying pathophysiology of Alzheimer's disease based on systemic chronic inflammation and neurovascular unit dysfunctionPrincipal Investigator

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The role of neurovascular unit in pathogenesis of Alzheimer's diseasePrincipal Investigator

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The role of white matter lesions in the pathophysiology of ADPrincipal Investigator

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distal myopathy with abnormal GNE gene

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Treatment of distal myopathy caused by GNE gene aberration

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Pathomechanism and treatment of distal myopathy with rimmed vacuoles and GNE gene aberration

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[Book] サルコードーシス診療の手引き20232023

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[Book] 軽度認知障害(MCI)診療マニュアル2023

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[Book] Brain Nursing2020

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Kimura Noriyuki 木村成志

KIMURA Noriyuki 木村成志