Hosogi Shigekuni 細木誠之

… Alternative Names

HOSOGI Shigekuni 細木誠之

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Researcher Number	30433254
Other IDs
Affiliation (Current)	2025: 京都薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 京都薬科大学, 薬学部, 准教授 2018 – 2023: 京都薬科大学, 薬学部, 准教授 2015 – 2017: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2015: 京都府立医科大学, 大学院医学研究科, 講師 2014: 京都府立医科大学, 医学(系)研究科(研究院), その他 … More 2014: 京都府立医科大学, 医学(系)研究科(研究院), 客員講師 2014: 京都府立医科大学, 大学院医学研究科, 客員講師 2012 – 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2012: 京都府立医科大学, 医学(系)研究科, 講師 2010: 京都府立医科大学, 医学研究科, 助教 Less
Review Section/Research Field	Principal Investigator General physiology / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator General physiology / Basic Section 58010:Medical management and medical sociology-related / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 28040:Nanobioscience-related / Orthopaedic surgery / Respiratory organ internal medicine
Keywords	Principal Investigator クロライドイオン / COPD / ＣOPD / 気道線毛運動 / pH制御イオン輸送体 / 気道線毛細胞 / pH / 高ＣO2 / 気道上皮線毛細胞 / ｐＨ … More / 粘液線毛クリアランス / プロトンダイナミクス / proton dynamics / 癌幹細胞 / chloride ion / autophagy / リソソーム / オートファジー … More Except Principal Investigator pH / ビッグデータ / 大規模保険請求情報 / 医療ビッグデータ / 臨床疫学 / 薬剤疫学 / 保険請求情報 / リアルワールドデータ / 肺繊維症 / ドーパミン受容体 / ブレオマイシン / ドーパミン / ブレオマイシンマウスモデル / 肺線維症 / Cancer cell / Imaging / Reactive Oxygen Species / redox biology / nano-sensor / hydrogen peroxides / SERS / nanosensor / cell surface pH / cell surface / Hydrogen peroxide / Nanosensors / Raman spectroscopy / インスリン抵抗性 / 組織間質液 / 糖尿病 / Cl-チャネル / KCC / NKCC / 細胞接着因子 / WNKキナーゼ / 細胞運動 / 細胞接着 / 細胞増殖 / 細胞内Cl-濃度 / プロスタシン / Rac1 / 食塩感受性高血圧 / プロテアーゼ活性 / ケルセチン / Na+再吸収 / ENaC / フラボノイド / エクソゾーム / がん免疫 / 細胞内小器官 / 骨肉種 / マクロファージ / 免疫療法 / エキソゾーム / 微粒子 / 光線力学的治療法 / アクリジンオレンジ / 骨肉腫 / 肺水腫 / シグナリングアッセイ / アポトーシス / 肺胞上皮 / CD14 / エンドトキシン肺損傷 / TLR Less

気道上皮前駆細胞の細胞老化に対する超硫黄分子を標的とした革新的治療法の開発Principal Investigator
- Principal Investigator
  
  細木誠之
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kyoto Pharmaceutical University
Verification of clinical usefulness obtained in basic and clinical research with real-world data
- Principal Investigator
  
  Muraki Yuichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Kyoto Pharmaceutical University
Elucidation of the pathogenesis of pulmonary fibrosis mediated by dopamine receptors and development of novel therapeutic agents
- Principal Investigator
  
  Kawahito Yutaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyoto Prefectural University of Medicine
Nanometer scale resolution imaging of pH and reactive oxygen species on the outer membrane surface for fast and effective cell discrimination in cancer tissues.
- Principal Investigator
  
  Puppulin Leonardo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 28040:Nanobioscience-related
- Research Institution
  Kanazawa University
Development of airway mucociliary transport system activation therapy targeting ion transporters in COPDPrincipal Investigator
- Principal Investigator
  
  Hosogi Shigekuni
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Pharmaceutical University
  Kyoto Prefectural University of Medicine
the pH reguration system is new target of cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  Hosogi Shigekuni
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
Molecular mechanisms of cancer metastasis induced by disrupting the WNK kinase mediated cytosolic Cl- homeostasis
- Principal Investigator
  
  Miyazaki Hiroaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
Continuous pH measurement of interstitial fluid and clarification of pathogenic mechanism of insulin resistance by ISFET pH sensor
- Principal Investigator
  
  MARUNAKA Yoshinori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
Inhibitory mechanism of quercetin on ENaC in salt-sensitive hypertension
- Principal Investigator
  
  NIISATO Naomi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
The regulation of cytosolic chloride ion concentration which regulates autophagy system via regulation of lysosome acidity is a new target for cancer therapyPrincipal Investigator
- Principal Investigator
  
  HOSOGI SHIGEKUNI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kyoto Prefectural University of Medicine
Challenging study of immunotherapy for osteosarcoma usingmicroparticles induced by photodynamic therapy
- Principal Investigator
  
  KUSUZAKI Katsuyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Heian Jogakuin(St.Agnes')University
TLR gene expression in e ndotoxin-induced lung injury
- Principal Investigator
  
  IWASAKI Yoshinobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kyoto Prefectural University of Medicine

All 2023 2021 2019 2018 2017 2015 2014 2013 2012 2011 2009 2008 Other

All Journal Article Presentation Book Other

[Book] In Sarcoma Edited by Bulter EJ: Nova Science Publisher Inc.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Manamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Total Pages
  5
- Publisher
  New concept of limb salvage surgery in musculoskeletal sarcomas with acridine orange therapy
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] Plasma membrane anchored nanosensor for quantifying endogenous production of H2O2 in living cells2021
- Author(s)
  Hosogi Shigekuni、Marunaka Yoshinori、Ashihara Eishi、Yamada Tadaaki、Sumino Ayumi、Tanaka Hideo、Puppulin Leonardo
- Journal Title
  
  Biosensors and Bioelectronics
  
  Volume: 179 Pages: 113077-113077
- DOI
  10.1016/j.bios.2021.113077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05228, KAKENHI-PROJECT-18K19422, KAKENHI-PROJECT-18H03182
[Journal Article] Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells2019
- Author(s)
  Inui TA, Murakami K, Yasuda M, Hirano S, Ikeuchi Y, Kogiso H, Hosogi S, Inui T, MARUNAKA Y, Nakahari T
- Journal Title
  
  Pflugers Archiv - European Journal of Physiology
  
  Volume: 471 Issue: 8 Pages: 1127-1142
- DOI
  10.1007/s00424-019-02280-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03182, KAKENHI-PROJECT-17K08545
[Journal Article] Carbocisteine stimulated an increase in ciliary bend angle via a decrease in [Cl-]i in mouse airway cilia2019
- Author(s)
  Ikeuchi Y, Kogiso H, Hosogi S, Tanaka S, Shimamoto C, Matsumura H, Inui T, MARUNAKA Y, Nakahari T.
- Journal Title
  
  Pflugers Arch
  
  Volume: 471 Issue: 2 Pages: 365-380
- DOI
  10.1007/s00424-018-2212-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03182, KAKENHI-PROJECT-17K08545
[Journal Article] Seihai-to (TJ-90)-induced activation of airway ciliary beatings of mice: Ca2+ modulation of cAMP-Stimulated Ciliary Beatings via PDE1.2018
- Author(s)
  Kogiso H, Ikeuchi Y, Sumiya M, Hosogi S, Tanaka S, Shimamoto C, Inui T, MARUNAKA Y, Nakahari T.
- Journal Title
  
  nt J Mol Sci.
  
  Volume: 19 Issue: 3 Pages: 658-670
- DOI
  10.3390/ijms19030658
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Journal Article] A low [Ca2+]i-induced enhancement of cAMP-activated ciliary beating by PDE1A inhibition in mouse airway cilia.2017
- Author(s)
  Kogiso H, Hosogi S, Ikeuchi Y, Tanaka S, Shimamoto C, Matsumura H, Nakano T, Sano KI, Inui T, Marunaka Y, Nakahari T.
- Journal Title
  
  Pflugers Arch - Eur J Physiol
  
  Volume: 469 Issue: 9 Pages: 1215-1227
- DOI
  10.1007/s00424-017-1988-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Journal Article] Low pH of interstitial fluid around hippocampus of the brain in diabetic OLETF rats2014
- Author(s)
  Yoshinori Marunaka, Kanji Yoshimoto, Wataru Aoi, Shigekuni Hosogi, Hiroshi Ikegaya
- Journal Title
  
  Molecular and Cellular Therapies
  
  Volume: 2:6 Issue: 1 Pages: 1-4
- DOI
  10.1186/2052-8426-2-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25282199, KAKENHI-PROJECT-25670111
[Journal Article] Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell2014
- Author(s)
  Shigekuni Hosogi
- Journal Title
  
  Journal of cellular and molecular medicine
  
  Volume: 18 Issue: 6 Pages: 1-10
- DOI
  10.1111/jcmm.12257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790220
[Journal Article] cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell2014
- Author(s)
  細木誠之
- Journal Title
  
  Journal of cellular and molecular medicine
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790220
[Journal Article] Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell2014
- Author(s)
  Hosogi S, Kusuzaki K, Inui T, Wang X, MARUNAKA Y
- Journal Title
  
  J Cell Mol Med
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670111
[Journal Article] Improvement of insulin resistance, blood pressure and interstitial pH in early developmental stage of insulin resistance in OLETF rats by intake of propolis extracts.2013
- Author(s)
  Aoi W,Hosogi S, Niisato N, Yokoyama N, Hayata H, Miyazaki H, Kusuzaki K, Fukuda T, Fukui M, Nakamura N, Marunaka Y
- Journal Title
  
  BBRC
  
  Volume: 432 Pages: 650-653
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] A regulatory role of K^+-Cl^- cotransporter in the cell cycle progression of breast cancer MDA-MB-231 cells.2013
- Author(s)
  Kitagawa M, Niisato N, Shiozaki A, Ohta-Fujimoto M, Hosogi S, Miyazaki H, Ichikawa D, Otsuji E, Marunaka Y.
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 539巻 Issue: 1 Pages: 92-98
- DOI
  10.1016/j.abb.2013.06.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J03299, KAKENHI-PROJECT-24590283, KAKENHI-PROJECT-25460297, KAKENHI-PROJECT-25670111
[Journal Article] Trarlslationalresearch of photodynamic therapy with acridine orange which targets cancer acidity.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Nanamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 18 Pages: 1414-11420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] .Translationalresearch of photodynamic therapy with acridine orange which targets cancer acidity.2012
- Author(s)
  Kusuzaki K, Ashihara E, Hosogi S, Matsubara T, Satonaka H, Manamura T, Matsumine A, Murata H, Sudo A, Uchida A, Murata H, Baldini N, Fais S, Marunaka Y.
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 18 Pages: 1414-11420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] An inhibitor of Na/H(+) exchanger, ethy1-isopropyl amiloride (EIPA), diminishes proliferation of MKN28 human gastric cancer cells by decreasirlg the cytosolic Cl(-) concentration via DIDS-sensitive pathways。2012
- Author(s)
  Hosogi S, Miyazaki H, Nakajima KI, Ashihara E, Niisato N, Kusuzaki K, Marunaka Y.
- Journal Title
  
  Cell Physiol Biochem.
  
  Volume: 30 Pages: 1241-1253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659730
[Journal Article] An inhibitor of Na+/H+ exchanger (NHE), ethyl-isopropyl amiloride (EIPA), diminished proliferation of MNK28 human gastric cancer cells by decreasing the cytosolic Cl- concentration via DIDS-sensitive pathways.2012
- Author(s)
  Hosogi S
- Journal Title
  
  Cell Physiol Biochem
  
  Volume: 30 Issue: 5 Pages: 1241-1253
- DOI
  10.1159/000343315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591404, KAKENHI-PROJECT-24590283
[Journal Article] Phase II trial of weekly gemcitabine and split-dose cisplatin for advanced non-small-cell lung cancer.2009
- Author(s)
  HIRAMATSU ATSUSHI, IWASAKI YOSHINOBU, KOYAMA YASUNORI, TAMIYA NOBUYO, HOSOGI SHIGEKUNI, NAKANISHI MASAKI, KOHNO YOSHIHITO, UEDA MIKIO, ARIMOTO TAICHIRO, MARUNAKA YOSHINORI
- Journal Title
  
  Jpn J Clin Oncol 39(12)
  
  Pages: 779-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590932
[Journal Article] Effect of inducible nitric oxide synthase on apoptosis in Candida-induced acute lung iniury.2008
- Author(s)
  HOSOGI SHIGEKUNI
- Journal Title
  
  Biomedical Research 29・5
  
  Pages: 10-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590932
[Journal Article] Effect of inducible nitric oxide synthase on apoptosis2008
- Author(s)
  HOSOGI SHIGEKUNI, IWASAKI YOSHINOBU, YAMADA TAKAHIRO, KOMATANI-TAMIYA NOBUYO, HIRAMATSU ATSUSHI, KOHNO YOSHIHITO, UEDA MIKIO, ARIMOTO TAICHIRO, MARUNAKA YOSHINORI
- Journal Title
  
  Candida-induced acute lung injury 29
  
  Pages: 257-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590932
[Presentation] ドセタキセルを投与された肺がん患者における呼吸器感染症の発現状況の評価: 基礎研究で得られた仮説に対する大規模保険請求情報を用いた検証2023
- Author(s)
  豕瀬諒、後藤良太、細木誠之、芦原英司、村木優一
- Organizer
  第143回日本薬学会
- Data Source
  KAKENHI-PROJECT-21K10290
[Presentation] ヒト初代培養気道線毛細胞の線毛運動とイオン輸送解析2019
- Author(s)
  細木誠之　田宮暢代　瀬古友理恵　千原佑介　今林達哉　芦原英司　高山浩一
- Organizer
  第59回日本呼吸器学会学術講演会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Presentation] Epithelial ion secretion of human bronchial ciliary epithelium2019
- Author(s)
  Shigekuni Hosogi, Leonardo Puppulin, Hideo Tanaka, Eishi Ashihara
- Organizer
  The 9th Federation of Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Presentation] ヒト気道培養細胞における抗がん剤負荷時の線毛運動評価2019
- Author(s)
  田宮暢代、細木誠之、瀬古友利恵、千原佑介、今林達哉、髙山浩一
- Organizer
  第59回日本呼吸器学会学術講演会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Presentation] Ambroxol-Stimulated Increases in CBA and CBF in Airway Ciliary Cells of Mice2017
- Author(s)
  Hosogi S, Nakahari T, Marunaka Y.
- Organizer
  Dynein 2017 international workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Presentation] Ambroxol-Stimulated Increases in CBA and CBF Via pHi Increase and [Cl-]i Decrease in Airway Ciliary Cells of Mice2017
- Author(s)
  Hosogi S, Nakahari T, Marunaka Y
- Organizer
  American thoracic society 2017 international conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08545
[Presentation] Carbonic anhydrase iX inhibitors: new therapeu c tools for osteosarcoma treatment2015
- Author(s)
  F. Perut, F. Carta, G. Bonuccelli, G. Grisendi, G. Di Pompo, S. Avnet, F.V. Sbrana, S. Hosogi, K. Kusuzaki, M. Dominici, C.T. Supuran, N. Baldini
- Organizer
  2nd Annual MeetIng of the International Society of Cancer Metabolism
- Place of Presentation
  イタリア　ベネチア
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460301
[Presentation] Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell2014
- Author(s)
  Hosogi S, Marunaka Y, Niisato N, Miyazaki H.
- Organizer
  The 91st Annual Meeting of the Physiological Society of Japan
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-24590283
[Presentation] 細胞内クロライドイオンがリソソームpHを制御しオートファジーを制御する2014
- Author(s)
  Shigekuni Hosogi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学
- Data Source
  KAKENHI-PROJECT-24790220
[Presentation] Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell.2014
- Author(s)
  Hosogi S, Miyazaki H, Kusuzaki K, Niisato N, MARUNAKA Y.
- Organizer
  The Physiological Society of Japan
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-25670111
[Presentation] 細胞内クロライドイオンがリソソームpH を制御しオートファジーを制御する2014
- Author(s)
  細木誠之、丸中良典、新里直美、楠崎克之、宮崎裕明
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学、鹿児島
- Data Source
  KAKENHI-PROJECT-25460297
[Presentation] Regulation of lysosomal pH and autophagy by cytosolic chloride ions2013
- Author(s)
  Hosogi S, MARUNAKA Y
- Organizer
  Japan-Italy Joint Symposium on "Ionic Dynamics in Normal and Tumor Tissues
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25670111
[Presentation] What is the role of interstitial pH in diabetes mellitus? Improving action of propolis on DM symptom via pH regulation2013
- Author(s)
  MARUNAKA Y, Aoi W, Hosogi S, Niisato N, Yokoyama N, Hayata H, Miyazaki H, Kusuzaki K, Taruno A, Nomura T.
- Organizer
  The 16th International Symposium on Molecular Medicine
- Place of Presentation
  Creta Maris, Hersonissos, Crete, Greece
- Invited
- Data Source
  KAKENHI-PROJECT-25670111
[Presentation] 細胞内クロライドイオンがリソソームpHを制御し、オートファジーを制御する。2013
- Author(s)
  細木誠之
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24790220
[Presentation] Action of quercetin on cell Function via regulation of chloride ion transport.2013
- Author(s)
  MARUNAKA Y, Niisato N, Miyazaki H, Nakajima K, Hosogi S, Tarnu A, Yokoyama N
- Organizer
  The 13th International Conference on Functional and Medical Foods with Bioactive Compounds: Science and Practice
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25670111
[Presentation] C1-channeI/transporters as new targets for cancer therapies based on disruption of autophagy ability via modification of lysosome acidification.2012
- Author(s)
  Hosogis
- Organizer
  3^rd Symposium of the Internal Society for Proton Dynamics in Cancer
- Place of Presentation
  Kyoto Japan
- Data Source
  KAKENHI-PROJECT-23659730
[Presentation] An inhibitor of Na+/H+ exchanger (NHE), ethy1-isopropyl amiloride (EIPA), diminishes proliferation of MKN 28 human gastric cancer cells by decreasing the intracellular Cl- conce「1t「atiorl via DIDS-sensitive pathway2011
- Author(s)
  Hosogi S.
- Organizer
  2^nd Symposium of the Internal Society for Proton Dynamics in Cancer
- Place of Presentation
  Nice France
- Data Source
  KAKENHI-PROJECT-23659730
[]

1. MARUNAKA Yoshinori (00127036)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. NIISATO Naomi (00237645)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. MIYAZAKI Hiroaki (30360027)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. HOSOGI Shigekuni (30405261)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IWASAKI Yoshinobu (00203373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ARIMOTO Taichiro (30457965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. UEDA Mikio (40457966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KUSUZAKI Katsuyuki (30177993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. ASHIHARA Eishi (70275197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. NAKAJIMA Kenichi (40398392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOKOYAMA Noriko (40112958)

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12. HIDESHIMA Sho (10580433)

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13. Puppulin Leonardo (40771580)

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14. Kawahito Yutaka (50336731)

# of Collaborated Projects: 1 results

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15. Muraki Yuichi (50571452)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 中張隆司 (20189020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
17. 山田忠明 (00507048)

# of Collaborated Projects: 1 results

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18. 中村誠宏 (20411035)

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19. 河野正孝 (60405256)

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20. 豕瀬諒 (10868152)

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21. プップリンレオナルド

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22. 青井渉

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Hosogi Shigekuni 細木 誠之

HOSOGI Shigekuni 細木 誠之

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気道上皮前駆細胞の細胞老化に対する超硫黄分子を標的とした革新的治療法の開発Principal Investigator

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Development of airway mucociliary transport system activation therapy targeting ion transporters in COPDPrincipal Investigator

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the pH reguration system is new target of cancer stem cellsPrincipal Investigator

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The regulation of cytosolic chloride ion concentration which regulates autophagy system via regulation of lysosome acidity is a new target for cancer therapyPrincipal Investigator

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[Book] In Sarcoma Edited by Bulter EJ: Nova Science Publisher Inc.2012

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[Journal Article] Plasma membrane anchored nanosensor for quantifying endogenous production of H2O2 in living cells2021

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[Journal Article] Ciliary beating amplitude controlled by intracellular Cl- and a high rate of CO2 production in ciliated human nasal epithelial cells2019

Hosogi Shigekuni 細木誠之

HOSOGI Shigekuni 細木誠之