KIYOTANI Kazuma 清谷一馬

… Alternative Names

清谷一馬キヨタニカズマ

Kiyotani Kazuma 清谷一馬

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Researcher Number	30433642
Other IDs
Affiliation (Current)	2023: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所難病・免疫ゲノム研究センター, 副センター長 2023: 公益財団法人がん研究会, がんプレシジョン医療研究センター免疫ゲノム医療開発プロジェクト, グループリーダー
Affiliation (based on the past Project Information) *help	2023: 公益財団法人がん研究会, その他部局等, 研究員 2018 – 2021: 公益財団法人がん研究会, がんプレシジョン医療研究センター免疫ゲノム医療開発プロジェクト, 主任研究員 2012: 徳島大学, 疾患プロテオゲノム研究センター, 助教 2011: 徳島大学, 疾患ゲノム研究センター, 助教 2008 – 2010: The Institute of Physical and Chemical Research, 遺伝情報解析チーム, 研究員 2007: The Institute of Physical and Chemical Research, 薬理遺伝学研究チーム, 研究員
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor diagnosis / Medium-sized Section 50:Oncology and related fields Except Principal Investigator Basic Section 56030:Urology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator 遺伝子多型 / ネオアンチゲン / T細胞受容体 / チトクロームP450 / 相互作用 / 酵素活性 / SNP / 薬物代謝酵素 / トランスポーター / タモキシフェン … More / 乳がん / GWAS / ゲノムワイド関連解析 / 個人差 / 次世代シーケンサー / がんゲノム / TNBC / 変異 / 腫瘍浸潤T細胞 / ネオ抗原 / 翻訳後修飾 / ネオセルフ抗原 / LC-MS/MS … More Except Principal Investigator 腫瘍免疫 / 免疫チェックポイント阻害剤 / バイオマーカー / 腎癌 / 婦人科癌肉腫 / ゲノム情報 / 免疫微小環境 / T細胞受容体レパトワ / 免疫ゲノム / がん肉腫 / TCRレパトワ / 免疫細胞プロファイリング / 癌肉腫 / ハイパーミューテーター / レパトワ解析 / 免疫チェックポイント阻害薬 / 泌尿器科癌 / TCRシーケンス / エクソソーム / 腎がん / マルチオミックス解析 / リキッドバイオプシー / 腎細胞がん / 個別化医療 / マルチオミックス / プロテオゲノミクス / がん組織 / 血液バイオマーカー / 次世代シークエンサー / 質量分析 / 間質反応 / 内分泌療法 / CDK4/6 / 三次元培養 / バイオインフォ―マティクス / バイオインフォーマティクス / 食道胃接合部腺癌 / マイクロサテライト不安定性 / マクロサテライト不安定性 / 免疫回避機構 / 網羅的解析 / ニボルマブ / 子宮頸癌 / WEE1阻害薬 / CDK4/6阻害剤 / 免疫療法 / ネオアンチゲン / 遺伝子改変T細胞 Less

腫瘍およびリンパ節のがん反応性T細胞の機能・表現型の網羅的解析Principal Investigator
- Principal Investigator
  
  清谷一馬
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
CDK4/6阻害剤による抗腫瘍免疫応答活性化の解析と新規多剤併用免疫療法への応用
- Principal Investigator
  
  小林隆之
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
遺伝子改変ネオアンチゲン特異的T細胞による泌尿器癌個別化免疫療法の開発
- Principal Investigator
  
  加藤大悟
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
新規免疫治療創出を目指したMSI-low上部消化管腺癌の網羅的免疫・ゲノム解析
- Principal Investigator
  
  今村裕
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
子宮頸癌におけるWEE1阻害薬の検討およびその免疫環境の評価
- Principal Investigator
  
  池田悠至
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nihon University
Exploration of novel therapeutic targets for renal cancer by multi-omics analysis and development of treatment algorithm
- Principal Investigator
  
  Ujike Takeshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Comprehensive analysis of cancer-specific antigens recognized by tumor-infiltrating T cellsPrincipal Investigator
- Principal Investigator
  
  KIYOTANI Kazuma
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
間質応答を利用したホルモン受容体陽性乳がんの治療戦略の構築
- Principal Investigator
  
  上野貴之
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Japanese Foundation for Cancer Research
Immunogenomic landscape of gynecologic carcinosarcoma
- Principal Investigator
  
  Mori Seiichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Japanese Foundation for Cancer Research
Identification of predictive biomarkers for immune checkpoint inhibitors using T cell receptor repertoire analysis
- Principal Investigator
  
  Kato Taigo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Osaka University
Investigation of neo-self antigens derived from proteins with post-translational modificationPrincipal Investigator
- Principal Investigator
  
  Kiyotani Kazuma
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Japanese Foundation for Cancer Research
次世代シークエンサーによる新規乳がん関連遺伝子の探索Principal Investigator
- Principal Investigator
  
  清谷一馬
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  The University of Tokushima
Identification of polymorphisms in drug-transporter genes associated with clinical outcome of adjuvant tamoxifen therapy for breast cancer patientsPrincipal Investigator
- Principal Investigator
  
  KIYOTANI Kazuma
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
  The Institute of Physical and Chemical Research
Effects of protein/protein interaction on activity of drug metabolizing enzymesPrincipal Investigator
- Principal Investigator
  
  KIYOTANI Kazuma
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The Institute of Physical and Chemical Research

All 2022 2021 2020 2019 2018 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Perioperative circulating tumor DNA enables the identification of patients with poor prognosis in upper tract urothelial carcinoma2022
- Author(s)
  Nakano K, Koh Y, Yamamichi G, Yumiba S, Tomiyama E, Matsushita M, Hayashi Y, Wang C, Ishizuya Y, Yamamoto Y, Kato T, Hatano K, Kawashima A, Ujike T, Fujita K, Kiyotani K, Katayama K, Yamaguchi R, Imoto S, Imamura R, Nonomura N, Uemura M
- Journal Title
  
  Cancer Science
  
  Volume: -
- DOI
  10.1111/cas.15334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K12215, KAKENHI-PROJECT-19H03522
[Journal Article] Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy2021
- Author(s)
  Nagayama S, Low SK, Kiyotani K, Nakamura Y.
- Journal Title
  
  Cancers
  
  Volume: 12 Pages: 4803-4803
- DOI
  10.3390/cancers13194803
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20K07709
[Journal Article] Personalized immunotherapy in cancer precision medicine2021
- Author(s)
  Kiyotani K, Toyoshima Y, Nakamura Y
- Journal Title
  
  Cancer Biology and Medicine
  
  Volume: 18 Pages: 955-965
- DOI
  10.20892/j.issn.2095-3941.2021.0032
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] Immunogenomics in personalized cancer treatments2021
- Author(s)
  Kiyotani K, Toyoshima Y, Nakamura Y.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Pages: 901-907
- DOI
  10.1038/s10038-021-00950-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] Efficacy of Intranodal Neoantigen Peptide-pulsed Dendritic Cell Vaccine Monotherapy in Patients With Advanced Solid Tumors: A Retrospective Analysis2021
- Author(s)
  Morisaki T, Morisaki T, Kubo M, Onishi H, Hirano T, Morisaki S, Eto M, Monji K, Takeuchi A, Nakagawa S, Tanaka H, Koya N, Umebayashi M, Tsujimura K, Yew PY, Yoshimura S, Kiyotani K, Nakamura Y
- Journal Title
  
  Anticancer Research
  
  Volume: 41(8) Pages: 4101-4115
- DOI
  10.21873/anticanres.15213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-21K08672
[Journal Article] Neoantigens elicit T cell responses in breast cancer2021
- Author(s)
  Morisaki T, Kubo M, Umebayashi M, Yew PY, Yoshimura S, Park JH, Kiyotani K, Kai M, Yamada M, Oda Y, Nakamura Y, Morisaki T, Nakamura M.
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 13590-13590
- DOI
  10.1038/s41598-021-91358-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] Monitoring epidermal growth factor receptor C797S mutation in Japanese non-small cell lung cancer patients with serial cell‐free DNA evaluation using digital droplet PCR2021
- Author(s)
  Ariyasu Ryo、Uchibori Ken、Sasaki Takaaki、Tsukahara Mika、Kiyotani Kazuma、Yoshida Ryohei、Ono Yusuke、Kitazono Satoru、Ninomiya Hironori、Ishikawa Yuichi、Mizukami Yusuke、Yanagitani Noriko、Fujita Naoya、Nishio Makoto、Katayama Ryohei
- Journal Title
  
  Cancer Science
  
  Volume: - Pages: 2371-2380
- DOI
  10.1111/cas.14879
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03446, KAKENHI-PROJECT-18K15936, KAKENHI-PROJECT-20K21554, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-20K07671
[Journal Article] Peripheral T cell receptor repertoire features predict durable responses to anti-PD-1 inhibitor monotherapy in advanced renal cell carcinoma.2021
- Author(s)
  Kato T, Kiyotani K, Tomiyama E, Koh Y, Matsushita M, Hayashi Y, Nakano K, Ishizuya Y, Wang C, Hatano K, Kawashima A, Ujike T, Fujita K, Nonomura N, Uemura M.
- Journal Title
  
  Oncoimmunology
  
  Volume: 10 Pages: 1862948-1862948
- DOI
  10.1080/2162402x.2020.1862948
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K09133
[Journal Article] Immunogenomic landscape of gynecologic carcinosarcoma.2021
- Author(s)
  Gotoh Osamu、Kiyotani Kazuma、Chiba Tomohiro、Sugiyama Yuko、Takazawa Yutaka、Nemoto Kensaku、Kato Kazuyoshi、Tanaka Norio、Nomura Hidetaka、Hasegawa Kosei、Fujiwara Keiichi、Takamatsu Shiro、Matsumura Noriomi、Noda Tetsuo、Mori Seiichi
- Journal Title
  
  Gynecol Oncol
  
  Volume: 160 Pages: 547-556
- DOI
  10.1016/j.ygyno.2020.11.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09634, KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K07338, KAKENHI-PROJECT-21H02793
[Journal Article] Genomic and Pathological Characterization of Multiple Renal Cell Carcinoma Regions in Patient With Tuberous Sclerosis Complex: A Case Report2021
- Author(s)
  Yamamoto Tetsuya、Kato Taigo、Hatano Koji、Kawashima Atsunari、Ujike Takeshi、Fukuhara Shinichiro、Kiuchi Hiroshi、Imamura Ryoichi、Ibuki Naokazu、Kiyotani Kazuma、Kurashige Masako、Morii Eichi、Fujita Kazutoshi、Nonomura Norio、Uemura Motohide
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 691996-691996
- DOI
  10.3389/fonc.2021.691996
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K16585, KAKENHI-PROJECT-19H03522
[Journal Article] T-cell complexity and density are associated with sensitivity to neoadjuvant chemoradiotherapy in patients with rectal cancer2021
- Author(s)
  Akiyoshi T, Gotoh O, Tanaka N, Kiyotani K, Yamamoto N, Ueno M, Fukunaga Y, Mori S.
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 70 Pages: 509-518
- DOI
  10.1007/s00262-020-02705-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K07338, KAKENHI-PROJECT-18K08635, KAKENHI-PROJECT-18K08664
[Journal Article] Genomic alterations in gynecological malignancies: histotype-associated driver mutations, molecular subtyping schemes, and tumorigenic mechanisms2021
- Author(s)
  Mori S, Gotoh O, Kiyotani K, Low SK
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 66 Pages: 853-868
- DOI
  10.1038/s10038-021-00940-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-21H02793
[Journal Article] Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma2021
- Author(s)
  Wei T, Leisegang M, Xia M, Kiyotani K, Li N, Zeng C, Deng C, Jiang J, Harada M, Agrawal N, Li L, Qi H, Nakamura Y, Ren L.
- Journal Title
  
  OncoImmunology
  
  Volume: 10 Pages: 1929726-1929726
- DOI
  10.1080/2162402x.2021.1929726
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] SARS-CoV-2 genomic variations associated with mortality rate of COVID-192020
- Author(s)
  Toyoshima Y, Nemoto K, Matsumoto S, Nakamura Y, Kiyotani K.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65 Pages: 1075-1082
- DOI
  10.1038/s10038-020-0808-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] A Potential Mechanism of Anticancer Immune Response Coincident With Immune-related Adverse Events in Patients With Renal Cell Carcinoma.2020
- Author(s)
  Kato T, Tomiyama E, Koh Y, Matsushita M, Hayashi Y, Nakano K, Ishizuya YU, Wang C, Hatano K, Kawashima A, Ujike T, Kawasaki K, Morii E, Gotoh K, Eguchi H, Kiyotani K, Fujita K, Nonomura N, Uemura M.
- Journal Title
  
  Anticancer research
  
  Volume: 40 Pages: 4875-4883
- DOI
  10.21873/anticanres.14490
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K09133
[Journal Article] Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens2020
- Author(s)
  Paula Bottinger, Kiyotani Kazuma, et al.
- Journal Title
  
  Carcinogenesis
  
  Volume: . Pages: 1605-1615
- DOI
  10.1093/carcin/bgaa027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485, KAKENHI-PROJECT-19H03522
[Journal Article] Intranodal administration of neoantigen peptide-loaded dendritic cell vaccine elicits epitope-specific T cell responses and clinical effects in a patient with chemorefractory ovarian cancer with malignant ascites2020
- Author(s)
  Morisaki Takashi、Hikichi Tetsuro、Onishi Hideya、Morisaki Takafumi、Kubo Makoto、Hirano Tatsuya、Yoshimura Sachiko、Kiyotani Kazuma、Nakamura Yusuke
- Journal Title
  
  Immunol Invest
  
  Volume: 13 Pages: 1778721-1778721
- DOI
  10.1080/08820139.2020.1778721
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788
[Journal Article] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy2020
- Author(s)
  Chan Hiu Ting、Nagayama Satoshi、Chin Yoon Ming、Otaki Masumi、Hayashi Rie、Kiyotani Kazuma、Fukunaga Yosuke、Ueno Masashi、Nakamura Yusuke、Low Siew‐Kee
- Journal Title
  
  Molecular Oncology
  
  Volume: 14 Pages: 1719-1730
- DOI
  10.1002/1878-0261.12727
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07709, KAKENHI-PROJECT-19H03522
[Journal Article] Bioinformatic prediction of potential T cell epitopes for SARS-Cov-22020
- Author(s)
  Kiyotani K, Toyoshima Y, Nemoto K, Nakamura Y.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65 Pages: 569-575
- DOI
  10.1038/s10038-020-0771-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03522
[Journal Article] TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.2019
- Author(s)
  Tatsuo Matsuda, Eisaku Miyauchi, Yu-Wen Hsu, Satoshi Nagayama, Kazuma Kiyotani, Makda Zewde, Jae-Hyun Park, Taigo Kato, Makiko Harada, Shimpei Matsui, Masashi Ueno, Kazumasa Fukuda, Nobuaki Suzuki, Shoichi Hazama, Hiroaki Nagano, Hiroya Takeuchi, Wickii T. Vigneswaran, Yuko Kitagawa, Yusuke Nakamura
- Journal Title
  
  OncoImmunology
  
  Volume: 8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma2019
- Author(s)
  Ren Lili、Leisegang Matthias、Deng Boya、Matsuda Tatsuo、Kiyotani Kazuma、Kato Taigo、Harada Makiko、Park Jae-Hyun、Saloura Vassiliki、Seiwert Tanguy、Vokes Everett、Agrawal Nishant、Nakamura Yusuke
- Journal Title
  
  OncoImmunology
  
  Volume: 8
- DOI
  10.1080/2162402x.2019.1568813
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer.2019
- Author(s)
  Gong B., Kiyotani K., Sakata S., Nagano S., Kumehara S., Baba S., Besse B., Yanagitani N., Friboulet L., Nishio M., Takeuchi K., Kawamoto H., Fujita N., *Katayama R.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 216 Pages: 982-1000
- DOI
  10.1084/jem.20180870
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM2019
- Author(s)
  Goetz MP, Suman VJ, Nakamura Y, Kiyotani K, Jordan VC, Ingle JN.
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 37 Pages: 1982-1983
- DOI
  10.1200/jco.19.00504
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] Diagnostic utility of STAT6YE361 expression in classical Hodgkin lymphoma and related entities2019
- Author(s)
  Slambrouck CV, Huh J, Suh C, Song JY, Menon MP, Sohani AR, Duffield AS, Goldberg RC, Dama P, Kiyotani K, Godfrey J, Fitzpatrick C, Kline J, Smith SM, Jaffe ES, Hartmann S, Venkataraman G.
- Journal Title
  
  Modern Pathology
  
  Volume: 33 Pages: 834-845
- DOI
  10.1038/s41379-019-0428-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations2019
- Author(s)
  Miyauchi Eisaku、Matsuda Tatsuo、Kiyotani Kazuma、Low Siew-Kee、Hsu Yu-Wen、Tsukita Yoko、Ichinose Masakazu、Sakurada Akira、Okada Yoshinori、Saito Ryoko、Nakamura Yusuke
- Journal Title
  
  Cancer Science
  
  Volume: 110 Pages: 867-874
- DOI
  10.1111/cas.13919
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15332, KAKENHI-PROJECT-18K19485
[Journal Article] Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors2019
- Author(s)
  Schreiber K, Karrison G, Wolf SP, Kiyotani K, Steiner M, Littmann ER, Pamer EG, Kammertoens T, Schreiber H, Leisegang M.
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 8 Pages: 192-202
- DOI
  10.1158/2326-6066.cir-19-0567
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
[Journal Article] A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer2018
- Author(s)
  Santa-Maria Cesar August、Kato Taigo、Park Jae-Hyun、Kiyotani Kazuma、Rademaker Alfred、Shah Ami N.、Gross Leeaht、Blanco Luis Z.、Jain Sarika、Flaum Lisa、Tellez Claudia、Stein Regina、Uthe Regina、Gradishar William J.、Cristofanilli Massimo、Nakamura Yusuke、Giles Francis J.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Pages: 18985-18996
- DOI
  10.18632/oncotarget.24867
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment2018
- Author(s)
  Ko Tai-Ming、Kiyotani Kazuma、Chang Jeng-Sheng、Park Jae-Hyun、Yin Yew Poh、Chen Yuan-Tsong、Wu Jer-Yuarn、Nakamura Yusuke
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Pages: 2671-2677
- DOI
  10.1093/hmg/ddy176
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] The era of immunogenomics/immunopharmacogenomics2018
- Author(s)
  Zewde Makda、Kiyotani Kazuma、Park Jae-Hyun、Fang Hua、Yap Kai Lee、Yew Poh Yin、Alachkar Houda、Kato Taigo、Mai Tu H.、Ikeda Yuji、Matsuda Tatsuo、Liu Xiao、Ren Lili、Deng Boya、Harada Makiko、Nakamura Yusuke
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 63 Pages: 865-875
- DOI
  10.1038/s10038-018-0468-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor?Engineered T Cells for Ovarian Cancer2018
- Author(s)
  Matsuda Tatsuo、Leisegang Matthias、Park Jae-Hyun、Ren Lili、Kato Taigo、Ikeda Yuji、Harada Makiko、Kiyotani Kazuma、Lengyel Ernst、Fleming Gini F.、Nakamura Yusuke
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 24 Pages: 5357-5367
- DOI
  10.1158/1078-0432.ccr-18-0142
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Journal Article] A Commentary on Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.2013
- Author(s)
  Kiyotani K, et al.
- Journal Title
  
  J Hum Genet
  
  Volume: (In press)
- DOI
  10.1038/jhg.2012.142
- NAID
  10031156424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24501342
[Journal Article] Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese2012
- Author(s)
  Poh-Yin Yew, Taisei Mushiroda, Kazuma Kiyotani, Gopala Krishnan Govindasamy, Lee-Fah Yap, Soo-Hwang Teo, Paul Vey-Hong Lim, Selvaratnam Govindaraju, Kananathan Ratnavelu, Choon-Kook Sam, Yoke-Yeow Yap, Alan Soo-Beng Khoo, Kin-Choo Pua, Yusuke Nakamura
- Journal Title
  
  Mol Carcinog
  
  Volume: (in press)
- DOI
  10.1002/mc.21857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans2012
- Author(s)
  Milimo Maimbo, Kazuma Kiyotani, Taisei Mushiroda, Collen Masimirembwa, Yusuke Nakamura
- Journal Title
  
  Eur J Clin Pharmacol
  
  Volume: 68 Pages: 267-271
- DOI
  10.1007/s00228-011-1118-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.2012
- Author(s)
  Kazuma Kiyotani*, Satoko Uno*, Taisei Mushiroda, Atsushi Takahashi, Michiaki Kubo, Naoki Mitsuhata, Shinomi Ina, Chikashi Kihara, Yasutoshi Kimura, Hiroki Yamaue, Koichi Hirata, Yusuke Nakamura, Hitoshi Zembutsu
- Journal Title
  
  Pharmacogenet Genomics.
  
  Volume: 22 Pages: 229-235
- DOI
  10.1097/fpc.0b013e32834e9eba
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-24300338
[Journal Article] Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients2012
- Author(s)
  Kiyotani, K., et.al.
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 131(1) Pages: 137-145
- DOI
  10.1007/s10549-011-1777-7
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22116010, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23390037, KAKENHI-PROJECT-221S0001
[Journal Article] Pharmacogenomics of tamoxifen : roles of drug metabolizing enzymes and transporters2012
- Author(s)
  Kiyotani K, et al
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 28 Pages: 122-131
- NAID
  130004463222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.2012
- Author(s)
  K.Kiyotani, T.Mushiroda, T.Tsunoda, T.Morizono, N.Hosono, M.Kubo, Y.Tanigawara, CK.Imamura, DA.Flockhart, F.Aki, K.Hirata, Y.Takatsuka, M.Okazaki, S.Ohsumi, T.Yamakawa, M.Sasa, Y.Nakamura, H.Zembutsu
- Journal Title
  
  Hum Mol Genet.
  
  Volume: (オンライン出版済) Pages: 1665-1672
- DOI
  10.1093/hmg/ddr597
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22134008, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23390037, KAKENHI-PROJECT-24300338
[Journal Article] Different effects of TERT, TP63, and CYP2A6 polymorphism on individual risk of tobacco-related lung cancer in male Japanese smokers.2011
- Author(s)
  Makiko Shimizu*, Kazuma Kiyotani*, Hideo Kunitoh, Tetsuya Kamataki, Hiroshi Yamazaki
- Journal Title
  
  J.Cancer Ther
  
  Volume: 2 Pages: 690-696
- DOI
  10.4236/jct.2011.25093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23790200
[Journal Article] A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese2011
- Author(s)
  Iida A
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 20 Pages: 3684-3692
- DOI
  10.1093/hmg/ddr268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-22590923, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23500433
[Journal Article] Human cytochrome P450 1A1 is a novel target gene of liver X receptorα2011
- Author(s)
  Norihito Shibahara, Yuiko Masunaga, Shunsuke Iwano, Hiroshi Yamazaki, Kazuma Kiyotani, Tetsuya Kamataki
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: 26 Pages: 451-457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Limited effects of frequent CYP2D6^*36-^*10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population.2010
- Author(s)
  Kiyotani K, et al
- Journal Title
  
  Int J Environ Res Public Health
  
  Volume: 7 Pages: 1065-1068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Biomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population2010
- Author(s)
  Taku Nagano, Makiko Shimizu, Kazuma Kiyotani, Tetsuya Kamataki, Ryohji Takano, Norie Murayama, Fumiaki Shono, Hiroshi Yamazaki
- Journal Title
  
  Int J Environ Res Public Healthi
  
  Volume: 7 Pages: 2953-2964
- DOI
  10.3390/ijerph7072953
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Development of new HLA-B* 3505 genotyping method using Invader assay2010
- Author(s)
  Naoya Hosono, Soranun Chantarangsu, Kazuma Kiyotani, Sadaaki Takata, Yumiko Tsuchiya, Surakameth Mahasirimongkol, Wasun Chantratita, Taisei Mushiroda, Yusuke Nakamura, Michiaki Kubo
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 20 Pages: 630-633
- DOI
  10.1097/fpc.0b013e32833ddc0a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Lessons for pharmacogenomics studies : association study between CYP2D6 genotype and tamoxifen response2010
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Fuminori Aki, Okazaki Yutaka, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 20 Pages: 565-568
- DOI
  10.1097/fpc.0b013e32833af231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen TherEfapy for Breast Cancer Patients.2010
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, David A. Flockhart, Zeruesenay Desta, Todd C. Skaar, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
- Journal Title
  
  J Clin Oncol 28
  
  Pages: 1287-1293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen Therapy for Breast Cancer Patients2010
- Author(s)
  Kiyotani K, et al.
- Journal Title
  
  Journal of Clinical Oncology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Limited effects of frequent CYP2D6* 36-* 10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population2010
- Author(s)
  Kazuma Kiyotani, Makiko Shimizu, Toshio Kumai, Tetsuya Kamataki, Shinichi Kobayashi, Hiroshi Yamazaki
- Journal Title
  
  Eur J Clin Pharmacol
  
  Volume: 66 Pages: 1065-1068
- DOI
  10.1007/s00228-010-0876-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Lessons for pharmacogenomics studies : association study between CYP2D6 genotype and tamoxifen response.2010
- Author(s)
  Kiyotani K, et al
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 20 Pages: 565-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790179
[Journal Article] Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese.2009
- Author(s)
  Masayuki Matsunaga, Hiroshi Yamazaki, Kazuma Kiyotani, Shunsuke Iwano, Junji Saruwatari, Kazuko Nakagawa, Akiko Soyama, Shogo Ozawa, Jun-ichi Sawada, Eiji Kashiyama, Moritoshi Kinoshita, Tetsuya Kamataki
- Journal Title
  
  Drug Metab Dispos 37
  
  Pages: 699-701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.2008
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura
- Journal Title
  
  Cancer Sci 99
  
  Pages: 967-972
- NAID
  10024006132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.2008
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Mitsunori Sasa, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Hitoshi Zembutsu
- Journal Title
  
  Cancer Sci 99
  
  Pages: 995-999
- NAID
  10024006283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Association of genetic polymorphisms in SLCOIB3 and ABCC2 with docetaxel-induced leukopenia2008
- Author(s)
  Kiyotani K, et. al.
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Journal Article] Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients received adjuvant tamoxifen therapy2008
- Author(s)
  Kiyotani K, et. al.
- Journal Title
  
  Cancer Science (in press)
- NAID
  10024006283
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] T細胞受容体レパトア解析を用いた免疫チェックポイント阻害剤奏効予測マーカーの開発.2021
- Author(s)
  加藤大悟, 波多野浩士, 河嶋厚成, 植村元秀, 清谷一馬, 中村祐輔, 野々村祝夫.
- Organizer
  第34回日本バイオセラピィ学会学術集会総会.
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Screening of targetable neoantigens shared by multiple cancer patients.2021
- Author(s)
  Kiyotani K, Nakamura Y.
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Epigenetic alteration of SALL3 contributes to chemoresistance in triple-negative breast cancer.2021
- Author(s)
  Matsushita Y, Komatsu M, Kiyotani K, Niinuma T, Suzuki H, Yoshimaru T, Tajima A, Imoto I, Honda J, Furukawa Y, Nakamura Y, Miyoshi Y, Sasa M, Katagiri T.
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Early dynamics of T cell clonotypes as potential surrogate biomarker for immune checkpoint inhibitors.2021
- Author(s)
  Kato T, Kiyotani K, Yamamoto A, Uemura T, Yamamichi G, Tomiyama E, Koh Y, Matsushita M, Hatano K, Kawashima A, Uemura M, Nonomura N.
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Generation of neoantigen-specific T cells for adoptive cell transfer for treating head and neck squamous cell carcinoma.2021
- Author(s)
  Lili R, Wei T, Leisegang M, Xia M, Kiyotani K, Li N, Zeng C, Deng C, Jiang J, Harada M, Agrawal N, Li L, Qi H, Nakamura Y.
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients2020
- Author(s)
  Kazuma Kiyotani, Yusuke Nakamura
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] リンパ節中の腫瘍反応性T細胞の同定と機能解析2020
- Author(s)
  清谷一馬、岡村和美、建智博、長山聡、中村祐輔
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Screening of cancer-reactive T cells in lymph nodes in colorectal cancer patients2020
- Author(s)
  Kazuma Kiyotani, Kazumi Okamura, Satoshi Nagayama, Yusuke Nakamura
- Organizer
  AACR Annual Meeting 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] T細胞受容体レパトア解析を用いた免疫チェックポイント阻害剤早期奏効予測バイオマーカーの探索2020
- Author(s)
  加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
- Organizer
  第108回日本泌尿器科学会総会
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] T cell receptor sequencing predict early response for immune-check point inhibitors in urological cancer2020
- Author(s)
  Taigo Kato, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Kazuma Kiyotani, Motohide Uemura, Norio Nonomura
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] 進行性腎細胞癌における免疫チェックポイント阻害剤早期奏効予測のための血液バイオマーカーの開発2020
- Author(s)
  加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
- Organizer
  第23回日本免疫治療学会
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] Elucidation of early predictive biomarker in urological cancer patients with immune checkpoint inhibitors using T cell receptor sequencing2020
- Author(s)
  加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
- Organizer
  第24回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] Identification of early predictive biomarker for immune checkpoint inhibitors by T cell receptor repertoire analysis in advanced kidney cancer patients2020
- Author(s)
  Taigo Kato, Kazuma Kiyotani, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura
- Organizer
  American Urological Association Annual Conference 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] Combined targeting of tumor-stroma and cancer cells by T cells is essential for eradication of solid tumors2020
- Author(s)
  Steven P. Wolf, Vasiliki Anastasopoulou, Madeline Steiner, Markus I. Diehl, Kimberley Borutta, Boris Engels, Poh Yin Yew, Kazuma Kiyotani, Yusuke Nakamura, Karin Schreiber, Hans Schreiber, Matthias Leisegang
- Organizer
  第79回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Elucidation of early predictive biomarker in urological cancer patients with immune checkpoint inhibitors using T cell receptor sequencing2020
- Author(s)
  Taigo Kato, Kazuma Kiyotani, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura
- Organizer
  第58回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-18K09133
[Presentation] ゲノムシーケンスデータからのネオアンチゲン予測と特異的T細胞の誘導2020
- Author(s)
  清谷一馬、中村祐輔
- Organizer
  第24回バイオ治療法研究会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Secreted PD-L1 variants caused by aberrant splicing mediate antiPD-L1 antibody resistance.2019
- Author(s)
  Gong B, Kiyotani K, Sakata S, Nishio M, Takeuchi K, Kawamoto H, Fujita N, Katayama R.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Identification of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019
- Author(s)
  Kiyotani K
- Organizer
  6th Annual Meeting of Colegio Mexicano para la Investigacion del Cancer
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] TCR repertoires in lung adenocarcinomas with and without EGFR mutation.2019
- Author(s)
  Miyauchi E, Matsuda T, Kiyotani K, Low SK, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Nakamura Y.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Progress and future of cancer immunotherapy2019
- Author(s)
  Kiyotani K
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Screening of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019
- Author(s)
  Kiyotani K, Nakamura Y.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Comparison of TCR repertoires between cancer tissues and lymph nodes in colorectal cancer patients.2019
- Author(s)
  Kiyotani K, Matsuda T, Miyauchi E, Hsu Y, Nagayama S, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y.
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.2019
- Author(s)
  Chan HT, Nagayama S, Chin YM, Hayashi R, Kiyotani K, Nakamura Y, Low SK
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Progress and future of cancer immunotherapy2019
- Author(s)
  Kiyotani K
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] Comparison of TCR repertoires between cancer tissues and lymph nodes in colorectal cancer patients.2019
- Author(s)
  Kiyotani K, Matsuda T, Miyauchi E, Hsu Y, Nagayama S, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y.
- Organizer
  AACR Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Screening of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019
- Author(s)
  Kiyotani K, Nakamura Y.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.2019
- Author(s)
  Chan HT, Nagayama S, Chin YM, Hayashi R, Kiyotani K, Nakamura Y, Low SK.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Secreted PD-L1 variants caused by aberrant splicing mediate antiPD-L1 antibody resistance.2019
- Author(s)
  Gong B, Kiyotani K, Sakata S, Nishio M, Takeuchi K, Kawamoto H, Fujita N, Katayama R.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Identification of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019
- Author(s)
  Kiyotani K
- Organizer
  6th Annual Meeting of Colegio Mexicano para la Investigacion del Cancer
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] TCR repertoires in lung adenocarcinomas with and without EGFR mutation.2019
- Author(s)
  Miyauchi E, Matsuda T, Kiyotani K, Low SK, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Nakamura Y.
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19H03522
[Presentation] T cell receptor repertoire analysis of lung adenocarcinoma harboring EGFR mutations2018
- Author(s)
  Miyauchi E, Matsuda T, Hsu Y, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Kiyotani K, Nakamura Y
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] NGSデータからのネオアンチゲン予測アルゴリズム開発および特異的T細胞の誘導2018
- Author(s)
  清谷一馬
- Organizer
  第31回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] TCR sequencing analysis of cancer tissues and lymph nodes in colorectal cancer patients2018
- Author(s)
  Kiyotani K, Matsuda T, Nagayama S, Miyauchi E, Hsu Y, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Establishment of T-cell receptor-engineered T cells: Inplications for head and neck squemous carcinoma2018
- Author(s)
  Ren L, Matsuda T, Deng B, Kiyotani K, Kato T, Park JH, Agrawal N, Nakamura Y
- Organizer
  第77回日本癌学会
- Data Source
  KAKENHI-PROJECT-18K19485
[Presentation] Excume sequencing of triple-negative breast cancer2012
- Author(s)
  Kiyotani K, et al.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-24501342
[Presentation] Association between polymorphisms in CYP2D6 and ABCC2 and clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients2010
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
- Organizer
  The American Society of Human Genetics 60th Annual Meeting(ASHG2010)
- Place of Presentation
  Washington DC
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] タモキシフェンの乳がん再発予防効果に関連する薬物トランスポーターの遺伝子多型2010
- Author(s)
  清谷一馬, 莚田泰誠, 今村知世, 細野直哉, 角田達彦, 久保充明, 谷川原祐介, 安藝史典, 平田公一, 高塚雄一, 岡崎稔, 大住省三, 山川卓, 笹三徳, 中村祐輔, 前佛均
- Organizer
  日本人類遺伝学会第55回大会
- Place of Presentation
  大宮(大宮ソニックシティ)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] タモキシフェンの乳がん再発予防効果に及ぼすCYP2D6およびABCC2遺伝子多型の影響2010
- Author(s)
  清谷一馬, 莚田泰誠, 今村知世, 細野直哉, 角田達彦, 久保充明, 谷川原祐介, 平田公一, 大住省三, 笹三徳, 中村祐輔, 前佛均
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都(国立京都国際会館)
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] Effects of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients2010
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
- Organizer
  日本薬物動態学会第25回年会(東京)
- Place of Presentation
  大宮(大宮ソニックシティ)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] Association between polymorphisms in CYP2D6 and ABCC2 and clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.2010
- Author(s)
  Kiyotani K, et al
- Organizer
  American Society of Human Genetics 60th Annual Meeting (ASHG2010)
- Place of Presentation
  Washington DC
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] Effects of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.2010
- Author(s)
  Kiyotani K, et al
- Organizer
  日本薬物動態学会第25回年会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] タモキシフェンの乳がん再発予防効果に及ぼすCYP2D6およびABCC2遺伝子多型の影響2010
- Author(s)
  清谷一馬, ら
- Organizer
  第31回日本臨床薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2010-12-03
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] タモキシフェンの乳がん再発予防効果に関連する薬物トランスポーターの遺伝子多型2010
- Author(s)
  清谷一馬, ら
- Organizer
  日本人類遺伝学会第55回大会
- Place of Presentation
  大宮
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-22790179
[Presentation] Effects of polymorphisms in CYP2D6 and PK-related genes on clinical efficacy of adjuvant tamoxifen treatment in Japanese breast cancer patients.2009
- Author(s)
  Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Takashi Yamakawa, Koichi Hirata, Minoru Okazaki, Shozo Ohsumi, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Tatsuhiko Tsunoda, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
- Organizer
  Cold Spring Harbor Laboratory Pharmacogenomics meeting
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Association of polymorphisms of CYP2D6 and other PK-related genes on recurrence-free survival in Japanese breast cancer patients receiving adjuvant tamoxifen therapy.2009
- Author(s)
  Kazuma Kiyotani, Taisei Mushiroda, Mitsunori Sasa, Takashi Yamakawa, Koichi Hirata, Minoru Okazaki, Shozo Ohsumi, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Tatsuhiko Tsunoda, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Hitoshi Zembutsu
- Organizer
  59th Annual Meeting, the American society of Human Genetics
- Place of Presentation
  Honolulu
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] CYP2D6 genotyping for functional gene dosage analysis by allele copy number detection.2009
- Author(s)
  Naoya Hosono, Mamoru Kato, Kazuma Kiyotani, Taisei Mushiroda, Keiko Yamazaki, Tatsuhiko Tsunoda, Hitoshi Zembutsu, Yusuke Nakamura, Michiaki Kubo
- Organizer
  59th Annual Meeting, the American society of Human Genetics
- Place of Presentation
  Honolulu
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] 乳がん患者におけるタモキシフェンの再発予防効果と薬物代謝酵素の遺伝子型2009
- Author(s)
  清谷一馬, ら
- Organizer
  日本人類遺伝学会第54回年会
- Place of Presentation
  東京
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Association of polymorphisms of CYP2D6 and other PK-related genes on recurrence-free survival in Japanese breast cancer patients receiving adjuvant tamoxifen therapy2009
- Author(s)
  清谷一馬, et al
- Organizer
  59th Annual Meeting, the American society of Human Genetics
- Place of Presentation
  Honolulu
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Effects of polymorphisms in CYP2D6 and PK-related genes on clinical efficacy of adjuvant tamoxifen treatment in Japanese breast cancer patients2009
- Author(s)
  清谷一馬, et al
- Organizer
  Cold Spring Harbor Laboratory Pharmacogenomics meeting
- Place of Presentation
  London
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] 乳がん患者におけるタモキシフェンの再発予防効果と薬物代謝酵素の遺伝子型.2009
- Author(s)
  清谷一馬, 莚田泰誠, 笹三徳, 山川卓, 平田公一, 岡崎稔, 大住省三, 高塚雄一, 角田達彦, 細野直哉, 久保充明, 前佛均, 中村祐輔
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  東京
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] 乳がん患者におけるタモキシフェンの再発予防効果に及ぼすCYP2D6遺伝子型の影響2008
- Author(s)
  清谷一馬, ら
- Organizer
  日本臨床薬理学会第29回年会
- Place of Presentation
  新宿
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Effects of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.2008
- Author(s)
  Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Koichi Hirata, Minoru Okazaki, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
- Organizer
  The American Society of Human Genetics 58th Annual Meeting (ASHG2008)
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Effects of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy2008
- Author(s)
  Kiyotani K, et al
- Organizer
  58^<th> Annual Meeting, the American society of Human Genetics
- Place of Presentation
  Philadelphia
- Year and Date
  2008-11-12
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] ドセタキセルの副作用に関連するSLCO1B3およびABCC2遺伝子多型.2008
- Author(s)
  清谷一馬, 莚田泰誠, 久保充明, 前佛均, 杉山雄一, 中村祐輔
- Organizer
  日本人類遺伝学会第53回大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] 乳がん患者におけるタモキシフェンの再発予防効果に及ぼすCYP2D6遺伝子型の影響.2008
- Author(s)
  清谷一馬, 前佛均, 莚田泰誠, 中村祐輔
- Organizer
  第29回日本臨床薬理学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] ドセタキセルの副作用に関連するSLCO1B3およびABCC2遺伝子多型2008
- Author(s)
  清谷一馬, ら
- Organizer
  日本人類遺伝学会第53回年会
- Place of Presentation
  横浜
- Year and Date
  2008-09-29
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Clinical outcome with Adjuvant tamoxifen relative to patient CYP2D6 genotypes.2008
- Author(s)
  Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Koichi Hirata, Minoru Okazaki, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] Clinical Outcome with Adjuvant Tamoxifen Relative to Patient CYP2D6 Genotypes2008
- Author(s)
  清谷一馬, ら
- Organizer
  日本薬物動態学会第23回年会
- Place of Presentation
  熊本
- Year and Date
  2008-10-31
- Data Source
  KAKENHI-PROJECT-19790132
[Presentation] mPCR-RETINAおよびリアルタイムPCRを用いたCYP2D6ジェノタイピング方法の確立.2008
- Author(s)
  細野直哉, 久保充明, 加藤護, 角田達彦, 莚田泰誠, 清谷一馬, 佐藤寛子, 網谷花枝, 高田定暁, 前佛均, 中村祐輔
- Organizer
  日本人類遺伝学会第53回大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19790132

1. Mori Seiichi (10334814)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. Kato Taigo (70648021)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 植村元秀 (40631015)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. Ujike Takeshi (00738875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 吉丸哲郎 (80424729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 朝長毅 (80227644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 阿部雄一 (30731632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 黒田大祐 (60756732)

# of Collaborated Projects: 1 results

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9. 上野貴之 (40452362)

# of Collaborated Projects: 1 results

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10. 戸井雅和 (10207516)

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11. 杉本昌弘 (30458963)

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12. LOW SIEWKEE (40634720)

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# of Collaborated Products: 3 results
13. 今村裕 (70583045)

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14. 池田悠至 (80713453)

# of Collaborated Projects: 1 results

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15. 小林隆之 (50625738)

# of Collaborated Projects: 1 results

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16. 北野滋久 (60402682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ONISHI Hideya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. KATSUNO Masahisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. RYOUHEI Katayama

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. MATSUMURA Noriomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. NISHIO makoto

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# of Collaborated Products: 1 results
22. YANAGITANI noriko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. TAKEUCHI kengo

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# of Collaborated Products: 1 results
24. KATAYAMA Norihiro

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# of Collaborated Products: 1 results
25. 森崎隆

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# of Collaborated Products: 2 results
26. 清水万紀子

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# of Collaborated Products: 1 results
27. 祖父江元

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# of Collaborated Products: 1 results
28. 飯田有俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 石川雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 内堀健

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# of Collaborated Products: 1 results
31. 藤田直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 水上裕輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 小野裕介

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# of Collaborated Products: 1 results
34. 前佛均

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# of Collaborated Products: 2 results
35. 谷川原祐介

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# of Collaborated Products: 2 results
36. 後藤理

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# of Collaborated Products: 1 results
37. 杉山裕子

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# of Collaborated Products: 1 results
38. 倉重真沙子

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# of Collaborated Products: 1 results
39. 秋吉高志

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40. 上野雅資

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# of Collaborated Products: 1 results
41. 坂田征士

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42. 角田達彦

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# of Collaborated Products: 1 results
43. 中村雅史

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# of Collaborated Products: 1 results
44. 片山琴絵

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KIYOTANI Kazuma 清谷 一馬

清谷 一馬 キヨタニ カズマ

Kiyotani Kazuma 清谷 一馬

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腫瘍およびリンパ節のがん反応性T細胞の機能・表現型の網羅的解析Principal Investigator

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Comprehensive analysis of cancer-specific antigens recognized by tumor-infiltrating T cellsPrincipal Investigator

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Investigation of neo-self antigens derived from proteins with post-translational modificationPrincipal Investigator

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次世代シークエンサーによる新規乳がん関連遺伝子の探索Principal Investigator

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Identification of polymorphisms in drug-transporter genes associated with clinical outcome of adjuvant tamoxifen therapy for breast cancer patientsPrincipal Investigator

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Effects of protein/protein interaction on activity of drug metabolizing enzymesPrincipal Investigator

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KIYOTANI Kazuma 清谷一馬

清谷一馬キヨタニカズマ

Kiyotani Kazuma 清谷一馬