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Kiyotani Kazuma  清谷 一馬

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KIYOTANI Kazuma  清谷 一馬

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Researcher Number 30433642
Affiliation (Current) 2022: 公益財団法人がん研究会, がんプレシジョン医療研究センター 免疫ゲノム医療開発プロジェクト, 主任研究員
Affiliation (based on the past Project Information) *help 2018 – 2021: 公益財団法人がん研究会, がんプレシジョン医療研究センター 免疫ゲノム医療開発プロジェクト, 主任研究員
2012: 徳島大学, 疾患プロテオゲノム研究センター, 助教
2011: 徳島大学, 疾患ゲノム研究センター, 助教
2008 – 2010: The Institute of Physical and Chemical Research, 遺伝情報解析チーム, 研究員
2007: The Institute of Physical and Chemical Research, 薬理遺伝学研究チーム, 研究員
Review Section/Research Field
Principal Investigator
Medical pharmacy / Tumor diagnosis / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 50:Oncology and related fields
Except Principal Investigator
Basic Section 56030:Urology-related / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Basic Section 56040:Obstetrics and gynecology-related
Keywords
Principal Investigator
遺伝子多型 / ネオアンチゲン / T細胞受容体 / チトクロームP450 / 相互作用 / 酵素活性 / SNP / 薬物代謝酵素 / トランスポーター / タモキシフェン … More / 乳がん / GWAS / ゲノムワイド関連解析 / 個人差 / 次世代シーケンサー / がんゲノム / TNBC / 変異 / 腫瘍浸潤T細胞 / ネオ抗原 / 翻訳後修飾 / ネオセルフ抗原 / LC-MS/MS … More
Except Principal Investigator
腫瘍免疫 / バイオマーカー / 免疫チェックポイント阻害剤 / 腎癌 / 婦人科癌肉腫 / ゲノム情報 / 免疫微小環境 / T細胞受容体レパトワ / 免疫ゲノム / がん肉腫 / TCRレパトワ / 免疫細胞プロファイリング / 癌肉腫 / ハイパーミューテーター / レパトワ解析 / 免疫チェックポイント阻害薬 / 泌尿器科癌 / TCRシーケンス / エクソソーム / 間質反応 / 内分泌療法 / CDK4/6 / 三次元培養 / バイオインフォ―マティクス / バイオインフォーマティクス / 腎細胞がん / 次世代シークエンサー / マルチオミックス / 質量分析 / マルチオミックス解析 / CDK4/6阻害剤 / 食道胃接合部腺癌 / マクロサテライト不安定性 / 免疫回避機構 / 網羅的解析 / ニボルマブ / マイクロサテライト不安定性 / 子宮頸癌 / WEE1阻害薬 Less
  • Research Projects

    (13 results)
  • Research Products

    (98 results)
  • Co-Researchers

    (40 People)
  •  CDK4/6阻害剤による抗腫瘍免疫応答活性化の解析と新規多剤併用免疫療法への応用

    • Principal Investigator
      小林 隆之
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  遺伝子改変ネオアンチゲン特異的T細胞による泌尿器癌個別化免疫療法の開発

    • Principal Investigator
      加藤 大悟
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  新規免疫治療創出を目指したMSI-low上部消化管腺癌の網羅的免疫・ゲノム解析

    • Principal Investigator
      今村 裕
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  子宮頸癌におけるWEE1阻害薬の検討およびその免疫環境の評価

    • Principal Investigator
      池田 悠至
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Nihon University
  •  間質応答を利用したホルモン受容体陽性乳がんの治療戦略の構築

    • Principal Investigator
      上野 貴之
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  マルチオミックス解析による腎がん新規治療標的の探索と治療選択アルゴリズム開発

    • Principal Investigator
      氏家 剛
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  腫瘍浸潤T細胞が認識するがん特異的抗原の網羅的解析Principal Investigator

    • Principal Investigator
      清谷 一馬
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Immunogenomic landscape of gynecologic carcinosarcoma

    • Principal Investigator
      Mori Seiichi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Japanese Foundation for Cancer Research
  •  Identification of predictive biomarkers for immune checkpoint inhibitors using T cell receptor repertoire analysis

    • Principal Investigator
      Kato Taigo
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Osaka University
  •  Investigation of neo-self antigens derived from proteins with post-translational modificationPrincipal Investigator

    • Principal Investigator
      Kiyotani Kazuma
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Japanese Foundation for Cancer Research
  •  次世代シークエンサーによる新規乳がん関連遺伝子の探索Principal Investigator

    • Principal Investigator
      清谷 一馬
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor diagnosis
    • Research Institution
      The University of Tokushima
  •  Identification of polymorphisms in drug-transporter genes associated with clinical outcome of adjuvant tamoxifen therapy for breast cancer patientsPrincipal Investigator

    • Principal Investigator
      KIYOTANI Kazuma
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokushima
      The Institute of Physical and Chemical Research
  •  Effects of protein/protein interaction on activity of drug metabolizing enzymesPrincipal Investigator

    • Principal Investigator
      KIYOTANI Kazuma
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      The Institute of Physical and Chemical Research

All 2021 2020 2019 2018 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Peripheral T cell receptor repertoire features predict durable responses to anti-PD-1 inhibitor monotherapy in advanced renal cell carcinoma.2021

    • Author(s)
      Kato T, Kiyotani K, Tomiyama E, Koh Y, Matsushita M, Hayashi Y, Nakano K, Ishizuya Y, Wang C, Hatano K, Kawashima A, Ujike T, Fujita K, Nonomura N, Uemura M.
    • Journal Title

      Oncoimmunology

      Volume: 10 Pages: 1862948-1862948

    • DOI

      10.1080/2162402x.2020.1862948

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K09133
  • [Journal Article] Immunogenomic landscape of gynecologic carcinosarcoma.2021

    • Author(s)
      Gotoh Osamu、Kiyotani Kazuma、Chiba Tomohiro、Sugiyama Yuko、Takazawa Yutaka、Nemoto Kensaku、Kato Kazuyoshi、Tanaka Norio、Nomura Hidetaka、Hasegawa Kosei、Fujiwara Keiichi、Takamatsu Shiro、Matsumura Noriomi、Noda Tetsuo、Mori Seiichi
    • Journal Title

      Gynecol Oncol

      Volume: 160 Pages: 547-556

    • DOI

      10.1016/j.ygyno.2020.11.030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09634, KAKENHI-PROJECT-20K21665, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K07338
  • [Journal Article] T-cell complexity and density are associated with sensitivity to neoadjuvant chemoradiotherapy in patients with rectal cancer2021

    • Author(s)
      Akiyoshi T, Gotoh O, Tanaka N, Kiyotani K, Yamamoto N, Ueno M, Fukunaga Y, Mori S.
    • Journal Title

      Cancer Immunol Immunother

      Volume: 70 Pages: 509-518

    • DOI

      10.1007/s00262-020-02705-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K07338, KAKENHI-PROJECT-18K08635, KAKENHI-PROJECT-18K08664
  • [Journal Article] Monitoring epidermal growth factor receptor C797S mutation in Japanese non?small cell lung cancer patients with serial cell‐free DNA evaluation using digital droplet PCR2021

    • Author(s)
      Ariyasu Ryo、Uchibori Ken、Sasaki Takaaki、Tsukahara Mika、Kiyotani Kazuma、Yoshida Ryohei、Ono Yusuke、Kitazono Satoru、Ninomiya Hironori、Ishikawa Yuichi、Mizukami Yusuke、Yanagitani Noriko、Fujita Naoya、Nishio Makoto、Katayama Ryohei
    • Journal Title

      Cancer Science

      Volume: -

    • DOI

      10.1111/cas.14879

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K21554, KAKENHI-PROJECT-19H03446, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-19H03524, KAKENHI-PROJECT-18K15936
  • [Journal Article] SARS-CoV-2 genomic variations associated with mortality rate of COVID-192020

    • Author(s)
      Toyoshima Y, Nemoto K, Matsumoto S, Nakamura Y, Kiyotani K.
    • Journal Title

      Journal of Human Genetics

      Volume: 65 Pages: 1075-1082

    • DOI

      10.1038/s10038-020-0808-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Journal Article] A Potential Mechanism of Anticancer Immune Response Coincident With Immune-related Adverse Events in Patients With Renal Cell Carcinoma.2020

    • Author(s)
      Kato T, Tomiyama E, Koh Y, Matsushita M, Hayashi Y, Nakano K, Ishizuya YU, Wang C, Hatano K, Kawashima A, Ujike T, Kawasaki K, Morii E, Gotoh K, Eguchi H, Kiyotani K, Fujita K, Nonomura N, Uemura M.
    • Journal Title

      Anticancer research

      Volume: 40 Pages: 4875-4883

    • DOI

      10.21873/anticanres.14490

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K09133
  • [Journal Article] Cooperation of genes in HPV16 E6/E7-dependent cervicovaginal carcinogenesis trackable by endoscopy and independent of exogenous estrogens or carcinogens2020

    • Author(s)
      Paula Bottinger, Kiyotani Kazuma, et al.
    • Journal Title

      Carcinogenesis

      Volume: . Pages: 1605-1615

    • DOI

      10.1093/carcin/bgaa027

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485, KAKENHI-PROJECT-19H03522
  • [Journal Article] Intranodal administration of neoantigen peptide-loaded dendritic cell vaccine elicits epitope-specific T cell responses and clinical effects in a patient with chemorefractory ovarian cancer with malignant ascites2020

    • Author(s)
      Morisaki Takashi、Hikichi Tetsuro、Onishi Hideya、Morisaki Takafumi、Kubo Makoto、Hirano Tatsuya、Yoshimura Sachiko、Kiyotani Kazuma、Nakamura Yusuke
    • Journal Title

      Immunol Invest

      Volume: 13 Pages: 1778721-1778721

    • DOI

      10.1080/08820139.2020.1778721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09047, KAKENHI-PROJECT-19K09124, KAKENHI-PROJECT-19K22662, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K08620, KAKENHI-PROJECT-18K08682, KAKENHI-PROJECT-18K08788
  • [Journal Article] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy2020

    • Author(s)
      Chan Hiu Ting、Nagayama Satoshi、Chin Yoon Ming、Otaki Masumi、Hayashi Rie、Kiyotani Kazuma、Fukunaga Yosuke、Ueno Masashi、Nakamura Yusuke、Low Siew‐Kee
    • Journal Title

      Molecular Oncology

      Volume: 14 Pages: 1719-1730

    • DOI

      10.1002/1878-0261.12727

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07709, KAKENHI-PROJECT-19H03522
  • [Journal Article] Bioinformatic prediction of potential T cell epitopes for SARS-Cov-22020

    • Author(s)
      Kiyotani K, Toyoshima Y, Nemoto K, Nakamura Y.
    • Journal Title

      Journal of Human Genetics

      Volume: 65 Pages: 569-575

    • DOI

      10.1038/s10038-020-0771-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Journal Article] TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patients.2019

    • Author(s)
      Tatsuo Matsuda, Eisaku Miyauchi, Yu-Wen Hsu, Satoshi Nagayama, Kazuma Kiyotani, Makda Zewde, Jae-Hyun Park, Taigo Kato, Makiko Harada, Shimpei Matsui, Masashi Ueno, Kazumasa Fukuda, Nobuaki Suzuki, Shoichi Hazama, Hiroaki Nagano, Hiroya Takeuchi, Wickii T. Vigneswaran, Yuko Kitagawa, Yusuke Nakamura
    • Journal Title

      OncoImmunology

      Volume: 8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] Identification of neoantigen-specific T cells and their targets: implications for immunotherapy of head and neck squamous cell carcinoma2019

    • Author(s)
      Ren Lili、Leisegang Matthias、Deng Boya、Matsuda Tatsuo、Kiyotani Kazuma、Kato Taigo、Harada Makiko、Park Jae-Hyun、Saloura Vassiliki、Seiwert Tanguy、Vokes Everett、Agrawal Nishant、Nakamura Yusuke
    • Journal Title

      OncoImmunology

      Volume: 8

    • DOI

      10.1080/2162402x.2019.1568813

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] Secreted PD-L1 variants mediate resistance to PD-L1 blockade therapy in non-small cell lung cancer.2019

    • Author(s)
      Gong B., Kiyotani K., Sakata S., Nagano S., Kumehara S., Baba S., Besse B., Yanagitani N., Friboulet L., Nishio M., Takeuchi K., Kawamoto H., Fujita N., *Katayama R.
    • Journal Title

      Journal of Experimental Medicine

      Volume: 216 Pages: 982-1000

    • DOI

      10.1084/jem.20180870

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07205, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06327, KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
  • [Journal Article] Tamoxifen Metabolism and Breast Cancer Recurrence: A Question Unanswered by CYPTAM2019

    • Author(s)
      Goetz MP, Suman VJ, Nakamura Y, Kiyotani K, Jordan VC, Ingle JN.
    • Journal Title

      Journal of Clinical Oncology

      Volume: 37 Pages: 1982-1983

    • DOI

      10.1200/jco.19.00504

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
  • [Journal Article] Diagnostic utility of STAT6YE361 expression in classical Hodgkin lymphoma and related entities2019

    • Author(s)
      Slambrouck CV, Huh J, Suh C, Song JY, Menon MP, Sohani AR, Duffield AS, Goldberg RC, Dama P, Kiyotani K, Godfrey J, Fitzpatrick C, Kline J, Smith SM, Jaffe ES, Hartmann S, Venkataraman G.
    • Journal Title

      Modern Pathology

      Volume: 33 Pages: 834-845

    • DOI

      10.1038/s41379-019-0428-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
  • [Journal Article] Significant differences in T cell receptor repertoires in lung adenocarcinomas with and without epidermal growth factor receptor mutations2019

    • Author(s)
      Miyauchi Eisaku、Matsuda Tatsuo、Kiyotani Kazuma、Low Siew-Kee、Hsu Yu-Wen、Tsukita Yoko、Ichinose Masakazu、Sakurada Akira、Okada Yoshinori、Saito Ryoko、Nakamura Yusuke
    • Journal Title

      Cancer Science

      Volume: 110 Pages: 867-874

    • DOI

      10.1111/cas.13919

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15332, KAKENHI-PROJECT-18K19485
  • [Journal Article] Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors2019

    • Author(s)
      Schreiber K, Karrison G, Wolf SP, Kiyotani K, Steiner M, Littmann ER, Pamer EG, Kammertoens T, Schreiber H, Leisegang M.
    • Journal Title

      Cancer Immunology Research

      Volume: 8 Pages: 192-202

    • DOI

      10.1158/2326-6066.cir-19-0567

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-18K19485
  • [Journal Article] A pilot study of durvalumab and tremelimumab and immunogenomic dynamics in metastatic breast cancer2018

    • Author(s)
      Santa-Maria Cesar August、Kato Taigo、Park Jae-Hyun、Kiyotani Kazuma、Rademaker Alfred、Shah Ami N.、Gross Leeaht、Blanco Luis Z.、Jain Sarika、Flaum Lisa、Tellez Claudia、Stein Regina、Uthe Regina、Gradishar William J.、Cristofanilli Massimo、Nakamura Yusuke、Giles Francis J.
    • Journal Title

      Oncotarget

      Volume: 9 Pages: 18985-18996

    • DOI

      10.18632/oncotarget.24867

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] Immunoglobulin profiling identifies unique signatures in patients with Kawasaki disease during intravenous immunoglobulin treatment2018

    • Author(s)
      Ko Tai-Ming、Kiyotani Kazuma、Chang Jeng-Sheng、Park Jae-Hyun、Yin Yew Poh、Chen Yuan-Tsong、Wu Jer-Yuarn、Nakamura Yusuke
    • Journal Title

      Human Molecular Genetics

      Volume: 27 Pages: 2671-2677

    • DOI

      10.1093/hmg/ddy176

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] The era of immunogenomics/immunopharmacogenomics2018

    • Author(s)
      Zewde Makda、Kiyotani Kazuma、Park Jae-Hyun、Fang Hua、Yap Kai Lee、Yew Poh Yin、Alachkar Houda、Kato Taigo、Mai Tu H.、Ikeda Yuji、Matsuda Tatsuo、Liu Xiao、Ren Lili、Deng Boya、Harada Makiko、Nakamura Yusuke
    • Journal Title

      Journal of Human Genetics

      Volume: 63 Pages: 865-875

    • DOI

      10.1038/s10038-018-0468-1

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] Induction of Neoantigen-Specific Cytotoxic T Cells and Construction of T-cell Receptor?Engineered T Cells for Ovarian Cancer2018

    • Author(s)
      Matsuda Tatsuo、Leisegang Matthias、Park Jae-Hyun、Ren Lili、Kato Taigo、Ikeda Yuji、Harada Makiko、Kiyotani Kazuma、Lengyel Ernst、Fleming Gini F.、Nakamura Yusuke
    • Journal Title

      Clinical Cancer Research

      Volume: 24 Pages: 5357-5367

    • DOI

      10.1158/1078-0432.ccr-18-0142

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Journal Article] A Commentary on Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.2013

    • Author(s)
      Kiyotani K, et al.
    • Journal Title

      J Hum Genet

      Volume: (In press)

    • DOI

      10.1038/jhg.2012.142

    • NAID

      10031156424

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24501342
  • [Journal Article] The Malaysian NPC Study Group, Ching-Ching Ng. Identification of a functional variant in SPLUNC1 associated with nasopharyngeal carcinoma susceptibility among Malaysian Chinese2012

    • Author(s)
      Poh-Yin Yew, Taisei Mushiroda, Kazuma Kiyotani, Gopala Krishnan Govindasamy, Lee-Fah Yap, Soo-Hwang Teo, Paul Vey-Hong Lim, Selvaratnam Govindaraju, Kananathan Ratnavelu, Choon-Kook Sam, Yoke-Yeow Yap, Alan Soo-Beng Khoo, Kin-Choo Pua, Yusuke Nakamura
    • Journal Title

      Mol Carcinog

      Volume: (in press)

    • DOI

      10.1002/mc.21857

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] CYP2B6 genotype is a strong predictor of systemic exposure to efavirenz in HIV-infected Zimbabweans2012

    • Author(s)
      Milimo Maimbo, Kazuma Kiyotani, Taisei Mushiroda, Collen Masimirembwa, Yusuke Nakamura
    • Journal Title

      Eur J Clin Pharmacol

      Volume: 68 Pages: 267-271

    • DOI

      10.1007/s00228-011-1118-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] A genome-wide association study identifies four genetic markers for hematological toxicities in cancer patients receiving gemcitabine therapy.2012

    • Author(s)
      Kazuma Kiyotani*, Satoko Uno*, Taisei Mushiroda, Atsushi Takahashi, Michiaki Kubo, Naoki Mitsuhata, Shinomi Ina, Chikashi Kihara, Yasutoshi Kimura, Hiroki Yamaue, Koichi Hirata, Yusuke Nakamura, Hitoshi Zembutsu
    • Journal Title

      Pharmacogenet Genomics.

      Volume: 22 Pages: 229-235

    • DOI

      10.1097/fpc.0b013e32834e9eba

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-24300338
  • [Journal Article] Dose-adjustment study of tamoxifen based on CYP2D6 genotypes in Japanese breast cancer patients2012

    • Author(s)
      Kiyotani, K., et.al.
    • Journal Title

      Breast Cancer Res Treat

      Volume: 131(1) Pages: 137-145

    • DOI

      10.1007/s10549-011-1777-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22116010, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23390037, KAKENHI-PROJECT-221S0001
  • [Journal Article] Pharmacogenomics of tamoxifen : roles of drug metabolizing enzymes and transporters2012

    • Author(s)
      Kiyotani K, et al
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 28 Pages: 122-131

    • NAID

      130004463222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] A genome-wide association study identifies locus at 10q22 associated with clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients in Japanese.2012

    • Author(s)
      K.Kiyotani, T.Mushiroda, T.Tsunoda, T.Morizono, N.Hosono, M.Kubo, Y.Tanigawara, CK.Imamura, DA.Flockhart, F.Aki, K.Hirata, Y.Takatsuka, M.Okazaki, S.Ohsumi, T.Yamakawa, M.Sasa, Y.Nakamura, H.Zembutsu
    • Journal Title

      Hum Mol Genet.

      Volume: (オンライン出版済) Pages: 1665-1672

    • DOI

      10.1093/hmg/ddr597

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134008, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23390037, KAKENHI-PROJECT-24300338
  • [Journal Article] Different effects of TERT, TP63, and CYP2A6 polymorphism on individual risk of tobacco-related lung cancer in male Japanese smokers2011

    • Author(s)
      Makiko Shimizu*, Kazuma Kiyotani*, Hideo Kunitoh, Tetsuya Kamataki, Hiroshi Yamazaki
    • Journal Title

      J.Cancer Ther

      Volume: 2 Pages: 690-696

    • DOI

      10.4236/jct.2011.25093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23790200
  • [Journal Article] A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese2011

    • Author(s)
      Iida A
    • Journal Title

      Human Molecular Genetics

      Volume: 20 Pages: 3684-3692

    • DOI

      10.1093/hmg/ddr268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21229011, KAKENHI-PLANNED-22110005, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22129005, KAKENHI-PROJECT-22590923, KAKENHI-PROJECT-22790179, KAKENHI-PROJECT-23500433
  • [Journal Article] Human cytochrome P450 1A1 is a novel target gene of liver X receptorα2011

    • Author(s)
      Norihito Shibahara, Yuiko Masunaga, Shunsuke Iwano, Hiroshi Yamazaki, Kazuma Kiyotani, Tetsuya Kamataki
    • Journal Title

      Drug Metab Pharmacokinet

      Volume: 26 Pages: 451-457

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Limited effects of frequent CYP2D6^*36-^*10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population.2010

    • Author(s)
      Kiyotani K, et al
    • Journal Title

      Int J Environ Res Public Health

      Volume: 7 Pages: 1065-1068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Biomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population2010

    • Author(s)
      Taku Nagano, Makiko Shimizu, Kazuma Kiyotani, Tetsuya Kamataki, Ryohji Takano, Norie Murayama, Fumiaki Shono, Hiroshi Yamazaki
    • Journal Title

      Int J Environ Res Public Healthi

      Volume: 7 Pages: 2953-2964

    • DOI

      10.3390/ijerph7072953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Development of new HLA-B* 3505 genotyping method using Invader assay2010

    • Author(s)
      Naoya Hosono, Soranun Chantarangsu, Kazuma Kiyotani, Sadaaki Takata, Yumiko Tsuchiya, Surakameth Mahasirimongkol, Wasun Chantratita, Taisei Mushiroda, Yusuke Nakamura, Michiaki Kubo
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 630-633

    • DOI

      10.1097/fpc.0b013e32833ddc0a

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Lessons for pharmacogenomics studies : association study between CYP2D6 genotype and tamoxifen response2010

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Fuminori Aki, Okazaki Yutaka, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 565-568

    • DOI

      10.1097/fpc.0b013e32833af231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen TherEfapy for Breast Cancer Patients.2010

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, David A. Flockhart, Zeruesenay Desta, Todd C. Skaar, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
    • Journal Title

      J Clin Oncol 28

      Pages: 1287-1293

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Significant Effect of Polymorphisms in CYP2D6 and ABCC2 on Clinical Outcomes of Adjuvant Tamoxifen Therapy for Breast Cancer Patients2010

    • Author(s)
      Kiyotani K, et al.
    • Journal Title

      Journal of Clinical Oncology (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Limited effects of frequent CYP2D6* 36-* 10 tandem duplication allele on in vivo dextromethorphan metabolism in a Japanese population2010

    • Author(s)
      Kazuma Kiyotani, Makiko Shimizu, Toshio Kumai, Tetsuya Kamataki, Shinichi Kobayashi, Hiroshi Yamazaki
    • Journal Title

      Eur J Clin Pharmacol

      Volume: 66 Pages: 1065-1068

    • DOI

      10.1007/s00228-010-0876-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Lessons for pharmacogenomics studies : association study between CYP2D6 genotype and tamoxifen response.2010

    • Author(s)
      Kiyotani K, et al
    • Journal Title

      Pharmacogenet Genomics

      Volume: 20 Pages: 565-568

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Journal Article] Two novel CYP2D6*10 haplotypes as possible causes of a poor metabolic phenotype in Japanese.2009

    • Author(s)
      Masayuki Matsunaga, Hiroshi Yamazaki, Kazuma Kiyotani, Shunsuke Iwano, Junji Saruwatari, Kazuko Nakagawa, Akiko Soyama, Shogo Ozawa, Jun-ichi Sawada, Eiji Kashiyama, Moritoshi Kinoshita, Tetsuya Kamataki
    • Journal Title

      Drug Metab Dispos 37

      Pages: 699-701

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.2008

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura
    • Journal Title

      Cancer Sci 99

      Pages: 967-972

    • NAID

      10024006132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.2008

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Mitsunori Sasa, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Hitoshi Zembutsu
    • Journal Title

      Cancer Sci 99

      Pages: 995-999

    • NAID

      10024006283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Association of genetic polymorphisms in SLCOIB3 and ABCC2 with docetaxel-induced leukopenia2008

    • Author(s)
      Kiyotani K, et. al.
    • Journal Title

      Cancer Science (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Journal Article] Impact of CYP2D6*10 on recurrence-free survival in breast cancer patients received adjuvant tamoxifen therapy2008

    • Author(s)
      Kiyotani K, et. al.
    • Journal Title

      Cancer Science (in press)

    • NAID

      10024006283

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients2020

    • Author(s)
      Kazuma Kiyotani, Yusuke Nakamura
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] リンパ節中の腫瘍反応性T細胞の同定と機能解析2020

    • Author(s)
      清谷一馬、岡村和美、建智博、長山聡、中村祐輔
    • Organizer
      第24回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Screening of cancer-reactive T cells in lymph nodes in colorectal cancer patients2020

    • Author(s)
      Kazuma Kiyotani, Kazumi Okamura, Satoshi Nagayama, Yusuke Nakamura
    • Organizer
      AACR Annual Meeting 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] T細胞受容体レパトア解析を用いた免疫チェックポイント阻害剤早期奏効予測バイオマーカーの探索2020

    • Author(s)
      加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
    • Organizer
      第108回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] T cell receptor sequencing predict early response for immune-check point inhibitors in urological cancer2020

    • Author(s)
      Taigo Kato, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Kazuma Kiyotani, Motohide Uemura, Norio Nonomura
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] 進行性腎細胞癌における免疫チェックポイント阻害剤早期奏効予測のための血液バイオマーカーの開発2020

    • Author(s)
      加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
    • Organizer
      第23回日本免疫治療学会
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] Elucidation of early predictive biomarker in urological cancer patients with immune checkpoint inhibitors using T cell receptor sequencing2020

    • Author(s)
      加藤大悟、冨山栄輔、洪陽子、松下慎、中野剛佑、林裕次郎、波多野浩士、河嶋厚成、氏家剛、藤田和利、清谷一馬、植村元秀、野々村祝夫
    • Organizer
      第24回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] Identification of early predictive biomarker for immune checkpoint inhibitors by T cell receptor repertoire analysis in advanced kidney cancer patients2020

    • Author(s)
      Taigo Kato, Kazuma Kiyotani, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura
    • Organizer
      American Urological Association Annual Conference 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] Combined targeting of tumor-stroma and cancer cells by T cells is essential for eradication of solid tumors2020

    • Author(s)
      Steven P. Wolf, Vasiliki Anastasopoulou, Madeline Steiner, Markus I. Diehl, Kimberley Borutta, Boris Engels, Poh Yin Yew, Kazuma Kiyotani, Yusuke Nakamura, Karin Schreiber, Hans Schreiber, Matthias Leisegang
    • Organizer
      第79回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Elucidation of early predictive biomarker in urological cancer patients with immune checkpoint inhibitors using T cell receptor sequencing2020

    • Author(s)
      Taigo Kato, Kazuma Kiyotani, Eisuke Tomiyama, Yoko Koh, Makoto Matsusita, Yujiro Hayashi, Kosuke Nakano, Yu Ishizuya, Cong Wang, Koji Hatano, Atsunari Kawashima, Takeshi Ujike, Kazutoshi Fujita, Motohide Uemura, Norio Nonomura
    • Organizer
      第58回日本癌治療学会
    • Data Source
      KAKENHI-PROJECT-18K09133
  • [Presentation] ゲノムシーケンスデータからのネオアンチゲン予測と特異的T細胞の誘導2020

    • Author(s)
      清谷一馬、中村祐輔
    • Organizer
      第24回バイオ治療法研究会学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Secreted PD-L1 variants caused by aberrant splicing mediate antiPD-L1 antibody resistance.2019

    • Author(s)
      Gong B, Kiyotani K, Sakata S, Nishio M, Takeuchi K, Kawamoto H, Fujita N, Katayama R.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Identification of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019

    • Author(s)
      Kiyotani K
    • Organizer
      6th Annual Meeting of Colegio Mexicano para la Investigacion del Cancer
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] TCR repertoires in lung adenocarcinomas with and without EGFR mutation.2019

    • Author(s)
      Miyauchi E, Matsuda T, Kiyotani K, Low SK, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Nakamura Y.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Progress and future of cancer immunotherapy2019

    • Author(s)
      Kiyotani K
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Screening of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019

    • Author(s)
      Kiyotani K, Nakamura Y.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Comparison of TCR repertoires between cancer tissues and lymph nodes in colorectal cancer patients.2019

    • Author(s)
      Kiyotani K, Matsuda T, Miyauchi E, Hsu Y, Nagayama S, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y.
    • Organizer
      AACR Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.2019

    • Author(s)
      Chan HT, Nagayama S, Chin YM, Hayashi R, Kiyotani K, Nakamura Y, Low SK
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Progress and future of cancer immunotherapy2019

    • Author(s)
      Kiyotani K
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] Comparison of TCR repertoires between cancer tissues and lymph nodes in colorectal cancer patients.2019

    • Author(s)
      Kiyotani K, Matsuda T, Miyauchi E, Hsu Y, Nagayama S, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y.
    • Organizer
      AACR Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Screening of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019

    • Author(s)
      Kiyotani K, Nakamura Y.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Clinical significance of clonal hematopoiesis in the interpretation of blood liquid biopsy.2019

    • Author(s)
      Chan HT, Nagayama S, Chin YM, Hayashi R, Kiyotani K, Nakamura Y, Low SK.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Secreted PD-L1 variants caused by aberrant splicing mediate antiPD-L1 antibody resistance.2019

    • Author(s)
      Gong B, Kiyotani K, Sakata S, Nishio M, Takeuchi K, Kawamoto H, Fujita N, Katayama R.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Identification of cancer-reactive/neoantigen-specific T cells in peripheral blood and tumor tissues of cancer patients.2019

    • Author(s)
      Kiyotani K
    • Organizer
      6th Annual Meeting of Colegio Mexicano para la Investigacion del Cancer
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] TCR repertoires in lung adenocarcinomas with and without EGFR mutation.2019

    • Author(s)
      Miyauchi E, Matsuda T, Kiyotani K, Low SK, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Nakamura Y.
    • Organizer
      第78回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19H03522
  • [Presentation] T cell receptor repertoire analysis of lung adenocarcinoma harboring EGFR mutations2018

    • Author(s)
      Miyauchi E, Matsuda T, Hsu Y, Tsukita Y, Ichinose M, Sakurada A, Okada Y, Saito R, Kiyotani K, Nakamura Y
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] NGSデータからのネオアンチゲン予測アルゴリズム開発および特異的T細胞の誘導2018

    • Author(s)
      清谷一馬
    • Organizer
      第31回日本バイオセラピィ学会学術集会総会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] TCR sequencing analysis of cancer tissues and lymph nodes in colorectal cancer patients2018

    • Author(s)
      Kiyotani K, Matsuda T, Nagayama S, Miyauchi E, Hsu Y, Zewde M, Park JH, Kato T, Harada M, Suzuki N, Nagano H, Hazama S, Nakamura Y
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Establishment of T-cell receptor-engineered T cells: Inplications for head and neck squemous carcinoma2018

    • Author(s)
      Ren L, Matsuda T, Deng B, Kiyotani K, Kato T, Park JH, Agrawal N, Nakamura Y
    • Organizer
      第77回日本癌学会
    • Data Source
      KAKENHI-PROJECT-18K19485
  • [Presentation] Excume sequencing of triple-negative breast cancer2012

    • Author(s)
      Kiyotani K, et al.
    • Organizer
      第71回 日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(北海道)
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-24501342
  • [Presentation] Association between polymorphisms in CYP2D6 and ABCC2 and clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients2010

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
    • Organizer
      The American Society of Human Genetics 60th Annual Meeting(ASHG2010)
    • Place of Presentation
      Washington DC
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] タモキシフェンの乳がん再発予防効果に関連する薬物トランスポーターの遺伝子多型2010

    • Author(s)
      清谷一馬, 莚田泰誠, 今村知世, 細野直哉, 角田達彦, 久保充明, 谷川原祐介, 安藝史典, 平田公一, 高塚雄一, 岡崎稔, 大住省三, 山川卓, 笹三徳, 中村祐輔, 前佛均
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      大宮(大宮ソニックシティ)
    • Year and Date
      2010-10-28
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] タモキシフェンの乳がん再発予防効果に及ぼすCYP2D6およびABCC2遺伝子多型の影響2010

    • Author(s)
      清谷一馬, 莚田泰誠, 今村知世, 細野直哉, 角田達彦, 久保充明, 谷川原祐介, 平田公一, 大住省三, 笹三徳, 中村祐輔, 前佛均
    • Organizer
      第31回日本臨床薬理学会年会
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] Effects of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients2010

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Chiyo K. Imamura, Naoya Hosono, Tatsuhiko Tsunoda, Michiaki Kubo, Yusuke Tanigawara, Fuminori Aki, Koichi Hirata, Yuichi Takatsuka, Minoru Okazaki, Shozo Ohsumi, Takashi Yamakawa, Mitsunori Sasa, Yusuke Nakamura, Hitoshi Zembutsu
    • Organizer
      日本薬物動態学会第25回年会(東京)
    • Place of Presentation
      大宮(大宮ソニックシティ)
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] Association between polymorphisms in CYP2D6 and ABCC2 and clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.2010

    • Author(s)
      Kiyotani K, et al
    • Organizer
      American Society of Human Genetics 60th Annual Meeting (ASHG2010)
    • Place of Presentation
      Washington DC
    • Year and Date
      2010-11-03
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] Effects of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.2010

    • Author(s)
      Kiyotani K, et al
    • Organizer
      日本薬物動態学会第25回年会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] タモキシフェンの乳がん再発予防効果に及ぼすCYP2D6およびABCC2遺伝子多型の影響2010

    • Author(s)
      清谷一馬, ら
    • Organizer
      第31回 日本臨床薬理学会年会
    • Place of Presentation
      京都
    • Year and Date
      2010-12-03
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] タモキシフェンの乳がん再発予防効果に関連する薬物トランスポーターの遺伝子多型2010

    • Author(s)
      清谷一馬, ら
    • Organizer
      日本人類遺伝学会第55回大会
    • Place of Presentation
      大宮
    • Year and Date
      2010-10-28
    • Data Source
      KAKENHI-PROJECT-22790179
  • [Presentation] Effects of polymorphisms in CYP2D6 and PK-related genes on clinical efficacy of adjuvant tamoxifen treatment in Japanese breast cancer patients.2009

    • Author(s)
      Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Takashi Yamakawa, Koichi Hirata, Minoru Okazaki, Shozo Ohsumi, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Tatsuhiko Tsunoda, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
    • Organizer
      Cold Spring Harbor Laboratory Pharmacogenomics meeting
    • Place of Presentation
      London
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Association of polymorphisms of CYP2D6 and other PK-related genes on recurrence-free survival in Japanese breast cancer patients receiving adjuvant tamoxifen therapy.2009

    • Author(s)
      Kazuma Kiyotani, Taisei Mushiroda, Mitsunori Sasa, Takashi Yamakawa, Koichi Hirata, Minoru Okazaki, Shozo Ohsumi, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Tatsuhiko Tsunoda, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura, Hitoshi Zembutsu
    • Organizer
      59th Annual Meeting, the American society of Human Genetics
    • Place of Presentation
      Honolulu
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] CYP2D6 genotyping for functional gene dosage analysis by allele copy number detection.2009

    • Author(s)
      Naoya Hosono, Mamoru Kato, Kazuma Kiyotani, Taisei Mushiroda, Keiko Yamazaki, Tatsuhiko Tsunoda, Hitoshi Zembutsu, Yusuke Nakamura, Michiaki Kubo
    • Organizer
      59th Annual Meeting, the American society of Human Genetics
    • Place of Presentation
      Honolulu
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] 乳がん患者におけるタモキシフェンの再発予防効果と薬物代謝酵素の遺伝子型2009

    • Author(s)
      清谷一馬, ら
    • Organizer
      日本人類遺伝学会 第54回年会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-24
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Association of polymorphisms of CYP2D6 and other PK-related genes on recurrence-free survival in Japanese breast cancer patients receiving adjuvant tamoxifen therapy2009

    • Author(s)
      清谷一馬, et al
    • Organizer
      59th Annual Meeting, the American society of Human Genetics
    • Place of Presentation
      Honolulu
    • Year and Date
      2009-10-22
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Effects of polymorphisms in CYP2D6 and PK-related genes on clinical efficacy of adjuvant tamoxifen treatment in Japanese breast cancer patients2009

    • Author(s)
      清谷一馬, et al
    • Organizer
      Cold Spring Harbor Laboratory Pharmacogenomics meeting
    • Place of Presentation
      London
    • Year and Date
      2009-09-13
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] 乳がん患者におけるタモキシフェンの再発予防効果と薬物代謝酵素の遺伝子型.2009

    • Author(s)
      清谷一馬, 莚田泰誠, 笹三徳, 山川卓, 平田公一, 岡崎稔, 大住省三, 高塚雄一, 角田達彦, 細野直哉, 久保充明, 前佛均, 中村祐輔
    • Organizer
      日本人類遺伝学会第54回大会
    • Place of Presentation
      東京
    • Year and Date
      2009-09-24
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] 乳がん患者におけるタモキシフェンの再発予防効果に及ぼすCYP2D6遺伝子型の影響2008

    • Author(s)
      清谷一馬, ら
    • Organizer
      日本臨床薬理学会 第29回年会
    • Place of Presentation
      新宿
    • Year and Date
      2008-12-05
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Effects of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy.2008

    • Author(s)
      Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Koichi Hirata, Minoru Okazaki, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
    • Organizer
      The American Society of Human Genetics 58th Annual Meeting (ASHG2008)
    • Place of Presentation
      Philadelphia
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Effects of CYP2D6*10 on recurrence-free survival in breast cancer patients receiving adjuvant tamoxifen therapy2008

    • Author(s)
      Kiyotani K, et al
    • Organizer
      58^<th> Annual Meeting, the American society of Human Genetics
    • Place of Presentation
      Philadelphia
    • Year and Date
      2008-11-12
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] ドセタキセルの副作用に関連するSLCO1B3およびABCC2遺伝子多型.2008

    • Author(s)
      清谷一馬, 莚田泰誠, 久保充明, 前佛均, 杉山雄一, 中村祐輔
    • Organizer
      日本人類遺伝学会第53回大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] 乳がん患者におけるタモキシフェンの再発予防効果に及ぼすCYP2D6遺伝子型の影響.2008

    • Author(s)
      清谷一馬, 前佛均, 莚田泰誠, 中村祐輔
    • Organizer
      第29回日本臨床薬理学会年会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] ドセタキセルの副作用に関連するSLCO1B3およびABCC2遺伝子多型2008

    • Author(s)
      清谷一馬, ら
    • Organizer
      日本人類遺伝学会 第53回年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-09-29
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Clinical outcome with Adjuvant tamoxifen relative to patient CYP2D6 genotypes.2008

    • Author(s)
      Kazuma Kiyotani, Hitoshi Zembutsu, Taisei Mushiroda, Mitsunori Sasa, Koichi Hirata, Minoru Okazaki, Yuichi Takatsuka, Yoshimi Bando, Ikuko Sumitomo, Naoya Hosono, Michiaki Kubo, Yusuke Nakamura
    • Organizer
      日本薬物動態学会第23回年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] Clinical Outcome with Adjuvant Tamoxifen Relative to Patient CYP2D6 Genotypes2008

    • Author(s)
      清谷一馬, ら
    • Organizer
      日本薬物動態学会 第23回年会
    • Place of Presentation
      熊本
    • Year and Date
      2008-10-31
    • Data Source
      KAKENHI-PROJECT-19790132
  • [Presentation] mPCR-RETINAおよびリアルタイムPCRを用いたCYP2D6ジェノタイピング方法の確立.2008

    • Author(s)
      細野直哉, 久保充明, 加藤護, 角田達彦, 莚田泰誠, 清谷一馬, 佐藤寛子, 網谷花枝, 高田定暁, 前佛均, 中村祐輔
    • Organizer
      日本人類遺伝学会第53回大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19790132
  • 1.  Mori Seiichi (10334814)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  Kato Taigo (70648021)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  植村 元秀 (40631015)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 4.  吉丸 哲郎 (80424729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  朝長 毅 (80227644)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  上野 貴之 (40452362)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  戸井 雅和 (10207516)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  杉本 昌弘 (30458963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  LOW SIEWKEE (40634720)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  氏家 剛 (00738875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  阿部 雄一 (30731632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  黒田 大祐 (60756732)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  小林 隆之 (50625738)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  北野 滋久 (60402682)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  今村 裕 (70583045)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  池田 悠至 (80713453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KATSUNO Masahisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  MATSUMURA Noriomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  RYOUHEI Katayama
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 20.  NISHIO makoto
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  YANAGITANI noriko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  TAKEUCHI kengo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  ONISHI Hideya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  清水 万紀子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  祖父江 元
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  飯田 有俊
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  前佛 均
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 28.  谷川原 祐介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 29.  後藤 理
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  秋吉 高志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  上野 雅資
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  坂田 征士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  藤田 直也
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  角田 達彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  森崎 隆
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  中村 雅史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 37.  水上 裕輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 38.  小野 裕介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  石川 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  内堀 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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