Yamasaki Keishi 山崎啓之

… Alternative Names

YAMASAKI Keishi 山崎啓之

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Researcher Number	30435143
Other IDs
Affiliation (Current)	2025: 崇城大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2024: 崇城大学, 薬学部, 教授 2009 – 2011: Sojo University, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Physical pharmacy Except Principal Investigator Basic Section 47060:Clinical pharmacy-related
Keywords	Principal Investigator ドラッグデリバリー / アルブミン / 抗がん剤治療 / ナノ粒子 / 細網内皮系回避 / ドラッグデリバリーシステム / 脂肪酸 / 肺胞 / コンジュゲート / 薬物デリバリー … More / タンパク結合 / 吸入 / 肺内動態 / α_1-酸性糖タンパク質 / 薬物輸送 / 血清アルブミン / 膜インターフェイス … More Except Principal Investigator アルブミン / 一酸化窒素 / 膵臓がん / ドラッグデリバリー / NOラジカル / 膵がん / フェニル酪酸 / ニトロ化合物 / オートファジー / がん治療 / 細胞死 Less

Development of NO donors with high albumin affinity for treatment of pancreatic cancer
- Principal Investigator
  
  西弘二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Sojo University
Development of albumin-binding fatty acid-modified nanoparticles for effective cancer therapyPrincipal Investigator
- Principal Investigator
  
  山崎啓之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Sojo University
Development of albumin-binding nitric oxide donors for treatment of pancreatic cancer
- Principal Investigator
  
  Nishi Koji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Sojo University
Development of albumin-coated stealth nanoparticles for effective anticancer therapyPrincipal Investigator
- Principal Investigator
  
  Yamasaki Keishi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Sojo University
Development of novel drug delivery system by controlling of albumin disposition in lungPrincipal Investigator
- Principal Investigator
  
  Yamasaki Keishi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sojo University
Study on the serum protein-mediated drug transport in biological membrane interfacePrincipal Investigator
- Principal Investigator
  
  YAMASAKI Keishi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Sojo University

All 2023 2022 2021 2020 2019 2018 2017 2011 2009

All Journal Article Presentation Patent

[Journal Article] Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural?Chemical Investigation2022
- Author(s)
  Hirata Kenshiro、Kawai Akito、Chuang Victor Tuan Giam、Sakurama Keiki、Nishi Koji、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 5 Pages: 4413-4419
- DOI
  10.1021/acsomega.1c06220
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16060, KAKENHI-PROJECT-20K06995
[Journal Article] Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts2022
- Author(s)
  Beppu Takuro、Nishi Koji、Imoto Shuhei、Araki Waka、Setoguchi Itaru、Ueda Ayaka、Suetsugi Naho、Ishima Yu、Ikeda Tokunori、Otagiri Masaki、Yamasaki Keishi
- Journal Title
  
  Oncology Reports
  
  Volume: 48 Issue: 4 Pages: 178-178
- DOI
  10.3892/or.2022.8393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K07193, KAKENHI-PROJECT-21K19716, KAKENHI-PROJECT-20K06995
[Journal Article] Trimethoxy trityl groups as a potent substituent for anti-cancer cytidine analog prodrugs.2022
- Author(s)
  Ito C, Taguchi K, Moroi Y, Enoki Y, Tokuda R, Yamasaki K, Imoto S, Matsumoto K
- Journal Title
  
  J Pharm Sci
  
  Volume: 111 Issue: 8 Pages: 2201-2209
- DOI
  10.1016/j.xphs.2022.04.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] An in vitro comparative study of the binding of caspofungin and micafungin to plasma proteins.2022
- Author(s)
  Yamasaki K, Sakurama K, Nishi K, Tsukigawa K, Seo H, Otagiri M, Taguchi K
- Journal Title
  
  J Pharm Pharmacol
  
  Volume: 74 Issue: 1 Pages: 88-93
- DOI
  10.1093/jpp/rgab157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin2022
- Author(s)
  Kawai Akito、Kobashigawa Yoshihiro、Hirata Kenshiro、Morioka Hiroshi、Imoto Shuhei、Nishi Koji、Chuang Victor Tuan Giam、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  ACS Omega
  
  Volume: 7 Issue: 34 Pages: 29944-29951
- DOI
  10.1021/acsomega.2c02929
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16060, KAKENHI-PROJECT-20K06995
[Journal Article] Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure2022
- Author(s)
  Yamasaki Keishi、Teshima Honoka、Yukizawa Reina、Kuyama Koki、Tsukigawa Kenji、Nishi Koji、Otagiri Masaki、Kawai Akito
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 66 Issue: 1 Pages: 951-961
- DOI
  10.1021/acs.jmedchem.2c01790
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16060, KAKENHI-PROJECT-20K06995
[Journal Article] Effect of Fatty Acids and Uremic Toxins on the Binding of Nateglinide, an Insulin Secretagogue, to Site II on Human Serum Albumin2022
- Author(s)
  Nishi K, Yano A, Tsukigawa K, Chuang VTG, Otagiri M, Yamasaki K.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 6 Pages: 803-805
- DOI
  10.1248/bpb.b22-00116
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] In vitro and in vivo assessment of Atemoya fruit (Annona atemoya) for food-drug interactions.2022
- Author(s)
  Yamasaki K, Fujisaki-Hirakawa M, Taguchi K, Kadowaki D, Tsukigawa K, Nishi K, Otagiri M, Seo H
- Journal Title
  
  Eur J Drug Metab Pharmacokinet
  
  Volume: 47 Issue: 2 Pages: 177-185
- DOI
  10.1007/s13318-021-00739-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] The Nitrated Form of Nateglinide Induces Apoptosis in Human Pancreatic Cancer Cells Through a Caspase-dependent Mechanism.2022
- Author(s)
  Nishi K, Imoto S, Beppu T, Uchibori S, Yano A, Ishima YU, Ikeda T, Tsukigawa K, Otagiri M, Yamasaki K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 42 Issue: 3 Pages: 1333-1338
- DOI
  10.21873/anticanres.15601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07193, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-20K06995
[Journal Article] Possible Role of Electrolytes on the Formation of Precipitates during the Infusion of Nafamostat Mesilate in Hemodialysis2021
- Author(s)
  Yamasaki Keishi、Nishi Koji、Tsukigawa Kenji、Taguchi Kazuaki、Otagiri Masaki、Seo Hakaru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 2 Pages: 259-265
- DOI
  10.1248/bpb.b20-00808
- NAID
  130007979659
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-02-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] Effects of Uremic Toxins on the Binding of Aripiprazole to Human Serum Albumin2021
- Author(s)
  Koji Nishi, Keiki Sakurama, Hiroshi Watanabe, Toru Maruyama, Keishi Yamasaki, Masaki Otagiri
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 437-441
- DOI
  10.1248/bpb.b20-00929
- NAID
  130007993459
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-20K06995
[Journal Article] Interaction of Benzbromarone with Subdomains IIIA and IB/IIA on Human Serum Albumin as the Primary and Secondary Binding Regions2021
- Author(s)
  Yamasaki Keishi、Kawai Akito、Sakurama Keiki、Udo Nagiko、Yoshino Yuta、Saito Yuki、Tsukigawa Kenji、Nishi Koji、Otagiri Masaki
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 18 Issue: 3 Pages: 1061-1070
- DOI
  10.1021/acs.molpharmaceut.0c01004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K16060, KAKENHI-PROJECT-20K06995
[Journal Article] Pharmacokinetics of 4′-cyano-2′-deoxyguanosine, a novel nucleoside analog inhibitor of the resistant hepatitis B virus, in a rat model of chronic kidney disease2021
- Author(s)
  Hashimoto Mai、Taguchi Kazuaki、Imoto Shuhei、Yamasaki Keishi、Mitsuya Hiroaki、Otagiri Masaki
- Journal Title
  
  Journal of Infection and Chemotherapy
  
  Volume: 27 Issue: 5 Pages: 702-706
- DOI
  10.1016/j.jiac.2020.12.014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Evaluation of cytochrome P450-based drug metabolism in hemorrhagic shock rats that were transfused with native and an artificial red blood cell preparation, Hemoglobin-vesicles2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Sakai Hiromi、Ohtsuki Sumio、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 5 Pages: 417-424
- DOI
  10.1016/j.dmpk.2020.06.004
- NAID
  50014592883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Characterization of the Interaction of Daptomycin With Site II on Human Serum Albumin2020
- Author(s)
  Yamasaki Keishi、Sakurama Keiki、Nishi Koji、Watanabe Hiroshi、Maruyama Toru、Seo Hakaru、Otagiri Masaki、Taguchi Kazuaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 9 Pages: 2919-2924
- DOI
  10.1016/j.xphs.2020.06.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-20K06995
[Journal Article] Synthesis and In Vitro Assessment of pH-Sensitive Human Serum Albumin Conjugates of Pirarubicin2020
- Author(s)
  Tsukigawa Kenji、Imoto Shuhei、Yamasaki Keishi、Nishi Koji、Tsutsumi Toshihiko、Yokoyama Shoko、Ishima Yu、Otagiri Masaki
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Issue: 1 Pages: 22-22
- DOI
  10.3390/ph14010022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K16467, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-20K06995
[Journal Article] Effects of Oxidation of Human Serum Albumin on the Binding of Aripiprazole2020
- Author(s)
  Sakurama Keiki、Nishi Koji、Chuang Victor Tuan Giam、Hashimoto Mai、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 6 Pages: 1023-1026
- DOI
  10.1248/bpb.b20-00205
- NAID
  130007850247
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Pharmacokinetic Properties of Orally Administered 4′-Cyano-2′-deoxyguanosine, a Novel Nucleoside Analog Inhibitor of the Hepatitis B Virus, in Viral Liver Injury Model Rats2020
- Author(s)
  Hashimoto Mai、Taguchi Kazuaki、Imoto Shuhei、Yamasaki Keishi、Mitsuya Hiroaki、Otagiri Masaki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 43 Issue: 9 Pages: 1426-1429
- DOI
  10.1248/bpb.b20-00372
- NAID
  130007894989
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2020-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] Assessing cytochrome P450-based drug-drug interactions with hemoglobin-vesicles, an artificial red blood cell preparation, in healthy rats2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Sakai Hiromi、Ohtsuki Sumio、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 35 Issue: 5 Pages: 425-431
- DOI
  10.1016/j.dmpk.2020.06.005
- NAID
  50014592884
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Cell uptake and anti-tumor effect of liposomes containing encapsulated paclitaxel-bound albumin against breast cancer cells in 2D and 3D cultured models.2020
- Author(s)
  Okamoto Y, Taguchi K, Imoto S, Chuang VTG, Yamasaki K, Otagiri M
- Journal Title
  
  J Drug Deliv Sci Tech
  
  Volume: 55 Pages: 101381-101381
- DOI
  10.1016/j.jddst.2019.101381
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Hepatic Cytochrome P450 Profiles in Hemorrhagic Shock Model Rats After Transfusion With Stored Red Blood Cells2020
- Author(s)
  Tokuno Masahiro、Taguchi Kazuaki、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 109 Issue: 11 Pages: 3490-3495
- DOI
  10.1016/j.xphs.2020.08.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20K06995
[Journal Article] Possible roles of intestinal P-glycoprotein and cytochrome P450 3A on the limited oral absorption of irinotecan2020
- Author(s)
  Yamasaki Keishi、Hidaka Muneaki、Kawano Yohei、Furuya Yumiko、Ono Hiroshige、Arimori Kazuhiko
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 73 Issue: 2 Pages: 178-184
- DOI
  10.1093/jpp/rgaa009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06995
[Journal Article] Further Evidence Regarding the Important Role of Chlorine Atoms of Aripiprazole on Binding to the Site II Area of Human Albumin.2019
- Author(s)
  Sakurama K, Nishi K, Imoto S, Hashimoto M, Komatsu T, Morita Y, Taguchi K, Otagiri M, Yamasaki K
- Journal Title
  
  J Pharm Sci
  
  Volume: 108 Issue: 5 Pages: 1890-1895
- DOI
  10.1016/j.xphs.2018.11.045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Investigation of anti-tumor effect of doxorubicin-loaded human serum albumin nanoparticles prepared by a desolvation technique.2019
- Author(s)
  Kimura K, Yamasaki K, Nishi K, Taguchi K, Otagiri M
- Journal Title
  
  Cancer Chemother Pharmacol.
  
  Volume: 83 Issue: 6 Pages: 1113-1120
- DOI
  10.1007/s00280-019-03832-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17K08261
[Journal Article] Preparation, Characterization, and in Vitro/in Vivo Evaluation of Paclitaxel-Bound Albumin-Encapsulated Liposomes for the Treatment of Pancreatic Cancer2019
- Author(s)
  Okamoto Yuko、Taguchi Kazuaki、Sakuragi Mina、Imoto Shuhei、Yamasaki Keishi、Otagiri Masaki
- Journal Title
  
  ACS Omega
  
  Volume: 4 Issue: 5 Pages: 8693-8700
- DOI
  10.1021/acsomega.9b00537
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17K08261
[Journal Article] Enhanced dissolution and oral bioavailability of praziquantel by emulsification with human serum albumin followed by spray drying.2019
- Author(s)
  Yamasaki K, Taguchi K, Nishi K, Otagiri M, Seo H
- Journal Title
  
  Eur J Pharm Sci
  
  Volume: 139 Pages: 105064-105064
- DOI
  10.1016/j.ejps.2019.105064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Processing grapefruit juice with γ‐cyclodextrin attenuates its inhibitory effect on cytochrome P450 3A activity2019
- Author(s)
  Yamasaki Keishi、Iohara Daisuke、Oyama Yoko、Nishizaki Narumi、Kawazu Seitaro、Nishi Koji、Kadowaki Daisuke、Taguchi Kazuaki、Otagiri Masaki、Seo Hakaru
- Journal Title
  
  Journal of Pharmacy and Pharmacology
  
  Volume: 72 Issue: 3 Pages: 356-363
- DOI
  10.1111/jphp.13212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06774, KAKENHI-PROJECT-17K08261
[Journal Article] Interaction of Aripiprazole with Human α1-Acid Glycoprotein.2019
- Author(s)
  Nishi K, Sakurama K, Kobashigawa Y, Morioka H, Udo N, Hashimoto M, Imoto S, Yamasaki K, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 108 Issue: 12 Pages: 3911-3916
- DOI
  10.1016/j.xphs.2019.09.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] α1-Acid Glycoprotein Has the Potential to Serve as a Biomimetic Drug Delivery Carrier for Anticancer Agents.2019
- Author(s)
  Matsusaka K, Ishima Y, Maeda H, Kinoshita R, Ichimizu S, Taguchi K, Giam Chuang VT, Nishi K, Yamasaki K, Otagiri M, Watanabe H, Maruyama T
- Journal Title
  
  J Pharm Sci.
  
  Volume: 108(11) Issue: 11 Pages: 3592-3598
- DOI
  10.1016/j.xphs.2019.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-17K08261
[Journal Article] Biomimetic carbon monoxide delivery based on hemoglobin vesicles ameliorates acute pancreatitis in mice via the regulation of macrophage and neutrophil activity.2018
- Author(s)
  Taguchi K, Nagao S, Maeda H, Yanagisawa H, Sakai H, Yamasaki K, Wakayama T, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Drug Deliv
  
  Volume: 25 Issue: 1 Pages: 1266-1274
- DOI
  10.1080/10717544.2018.1477860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-17K08481, KAKENHI-PROJECT-18H02604
[Journal Article] Pharmacokinetic properties of a novel inosine analog, 4'-cyano-2'-deoxyinosine, after oral administration in rats.2018
- Author(s)
  Hashimoto M, Taguchi K, Ishiguro T, Kohgo S, Imoto S, Yamasaki K, Mitsuya H, Otagiri M
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 6 Pages: e0198636-e0198636
- DOI
  10.1371/journal.pone.0198636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites.2018
- Author(s)
  Yamasaki K, Nishi K, Anraku M, Taguchi K, Maruyama T, Otagiri M
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 14 Pages: 155-160
- DOI
  10.1016/j.bbrep.2018.05.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-17K08480
[Journal Article] Analysis of the binding of aripiprazole to human serum albumin: The importance of a chloro-group in the chemical structure.2018
- Author(s)
  Sakurama K, Kawai A, Tuan Giam Chuang V, Kanamori Y, Osa M, Taguchi K, Seo H, Maruyama T, Imoto S, Yamasaki K, Otagiri M
- Journal Title
  
  ACS Omega
  
  Volume: 3 Issue: 10 Pages: 13790-13797
- DOI
  10.1021/acsomega.8b02057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-15K16128
[Journal Article] Glutamine deprivation enhances acetyl-CoA carboxylase inhibitor-induced death of human pancreatic cancer cells.2018
- Author(s)
  Nishi K, Suzuki M, Yamamoto N, Matsumoto A, Iwase Y, Yamasaki K, Otagiri M, Yumita N
- Journal Title
  
  Anticancer Res
  
  Volume: 38 Issue: 12 Pages: 6683-6689
- DOI
  10.21873/anticanres.13036
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-17K08429, KAKENHI-PROJECT-18K12086, KAKENHI-PROJECT-16K01381
[Journal Article] Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core.2018
- Author(s)
  Okamoto Y, Taguchi K, Yamasaki K, Sakuragi M, Kuroda S, Otagiri M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 107 Issue: 1 Pages: 436-445
- DOI
  10.1016/j.xphs.2017.08.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-16H06314
[Journal Article] Pharmacokinetics studies of 4'-cyano-2'-deoxyguanosine, a potent inhibitor of the hepatitis B virus, in rats.2018
- Author(s)
  Hashimoto M, Taguchi K, Ishiguro T, Kohgo S, Imoto S, Yamasaki K, Mitsuya H, Otagiri M.
- Journal Title
  
  J Pharm Pharmacol
  
  Volume: 70 Issue: 6 Pages: 723-731
- DOI
  10.1111/jphp.12897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Crystal structure analysis of human serum albumin complexed with sodium 4-phenylbutyrate.2018
- Author(s)
  Kawai A, Yamasaki K, Enokida T, Miyamoto S, Otagiri M.
- Journal Title
  
  Biochem Biophys Rep
  
  Volume: 13 Pages: 78-82
- DOI
  10.1016/j.bbrep.2018.01.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-15K16128
[Journal Article] Effect of Endogenous Substances on the Binding of Sodium 4- Phenylbutyrate to Human Serum Albumin.2018
- Author(s)
  Yamasaki K, Nishi K, Enokida T, Taguchi K, Otagiri M
- Journal Title
  
  Acta Chim Pharm Indica
  
  Volume: 8 Pages: 1-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Preparation and <i>in Vitro</i> Analysis of Human Serum Albumin Nanoparticles Loaded with Anthracycline Derivatives2018
- Author(s)
  Kimura K, Yamasaki K, Nakamura H, Haratake M, Taguchi K, Otagiri M.
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 66 Issue: 4 Pages: 382-390
- DOI
  10.1248/cpb.c17-00838
- NAID
  130006602056
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Interaction of Protizinic Acid with Human Serum Albumin: Site-to-Site Displacement of Protizinic Acid by Ibuprofen.2017
- Author(s)
  Nishi K, Yamasaki K, Otagiri M
- Journal Title
  
  Acta Chim Pharm Indica
  
  Volume: 7 Pages: 1-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Species Differences in the Binding of Sodium 4-Phenylbutyrate to Serum Albumin.2017
- Author(s)
  Yamasaki K, Enokida T, Taguchi K, Miyamura S, Kawai A, Miyamoto S, Maruyama T, Seo H, Otagiri M.
- Journal Title
  
  J Pharm Sci
  
  Volume: 106 Issue: 9 Pages: 2860-2867
- DOI
  10.1016/j.xphs.2017.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-15K16128
[Journal Article] The Use of Hemoglobin Vesicles for Delivering Medicinal Gas for the Treatment of Intractable Disorders.2017
- Author(s)
  Taguchi K, Yamasaki K, Sakai H, Maruyama T, Otagiri M
- Journal Title
  
  J Pharm Sci
  
  Volume: 106 Issue: 9 Pages: 2392-2400
- DOI
  10.1016/j.xphs.2017.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-17K08481, KAKENHI-PROJECT-17H02087
[Journal Article] Long chain fatty acids alter the interactive binding of ligands to the two principal drug binding sites of human serum albumin.2017
- Author(s)
  Yamasaki K, Hyodo S, Taguchi K, Nishi K, Yamaotsu N, Hirono S, Chuang VTG, Seo H, Maruyama T, Otagiri M.
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 6 Pages: 1-15
- DOI
  10.1371/journal.pone.0180404
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions.2017
- Author(s)
  Kawai A, Chuang VTG, Kouno Y, Yamasaki K, Miyamoto S, Anraku M, Otagiri M.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1865 Issue: 8 Pages: 979-984
- DOI
  10.1016/j.bbapap.2017.04.004
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261, KAKENHI-PROJECT-17K08480, KAKENHI-PROJECT-15K16128
[Journal Article] Recombinant Human Serum Albumin Containing 3 Copies of Domain I, Has Significant <i>in Vitro</i> Antioxidative Capacity Compared to the Wild-Type2017
- Author(s)
  Matsushita S, Nishi K, Iwao Y, Ishima Y, Watanabe H, Taguchi K, Yamasaki K, Maruyama T, Otagiri M.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 10 Pages: 1813-1817
- DOI
  10.1248/bpb.b17-00528
- NAID
  130006110574
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08261
[Journal Article] Histidine146 of human serum albumin plays a prominent role at the interface of subdomains IA and IIA in allosteric ligand binding2011
- Author(s)
  Kaneko K, Chuang VT, Minomo A, Yamasaki K, Bhagavan NV, Maruyama T, Otagiri M
- Journal Title
  
  IUBMB Life
  
  Volume: 63 Pages: 277-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Journal Article] Competitive Displacement of Serum Protein Binding of Radiopharmaceuticals with Amino Acid Infusion Investigated with N-Isopropyl-p-123I-Iodoamphetamine2009
- Author(s)
  Kuga N, Shikano N, Takamura N, Nishii R, Yamasaki K, Kobayashi M, Nagamachi S, Tamura S, Kawai K
- Journal Title
  
  J. Nucl. Med
  
  Volume: 50 Pages: 1378-1383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590054
[Patent] sj2001UU2020
- Inventor(s)
  西弘二、山崎啓之、井本修平、小田切優樹、別府拓豪
- Industrial Property Rights Holder
  西弘二、山崎啓之、井本修平、小田切優樹、別府拓豪
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-010513
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] 酸性環境応答性を有するアルブミン結合型抗がん剤の抗腫瘍効果2023
- Author(s)
  月川　健士、井本　修平、今村　思音、入江　直樹、安藤　綾乃、西　弘二、小田切　優樹、山崎　啓之
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ニトロ化フェニル酪酸のヒト膵臓がん細胞死誘導におけるオートファジー阻害の関与2023
- Author(s)
  有村　吉史、西　弘二、別府　拓豪、森川　颯馬、松元　綾菜、月川　健士、小田切　優樹、山崎　啓之
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ニトロ化フェニル酪酸のヒト膵臓がん細胞死誘導におけるオートファジー阻害の関与2023
- Author(s)
  有村吉史、西弘二、別府拓豪、森川颯馬、松元綾菜、月川健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化イブプロフェンベンジルリンカーの細胞死誘導効果2022
- Author(s)
  有村吉史、西弘二、別府拓豪、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化イブプロフェンエチルリンカーの細胞死誘導効果2022
- Author(s)
  末次奈穂、別府拓豪、西弘二、月川健士、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] 酸応答性プロドラッグ置換基としてのメトキシトリチル基の有用性評価2022
- Author(s)
  田口　和明、伊藤　千尋、井本　修平、諸井　良江、榎木　裕紀、山崎　啓之、松元　一明
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ベンズブロマロンのヒト血清アルブミンへの結合に及ぼす尿酸および遊離脂肪酸の影響2022
- Author(s)
  山崎啓之、河合聡人、雪澤玲奈、齋藤友紀、月川健士、西弘二、小田切優樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] アルブミン結合能を利用した脂肪酸修飾ピラルビシン封入リポソームの調製と評価2022
- Author(s)
  長谷川　喬史、岡本　侑子、西　弘二、月川　健士、井本　修平、小田切　優樹、田口　和明、山崎　啓之
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] Structural basis of the change in the interaction between mycophenolic acid and subdomain IIA of human serum albumin during renal failure.2022
- Author(s)
  山崎　啓之、手島　帆乃香、雪澤　玲奈、久山　晃輝、月川　健士、西　弘二、小田切　優樹、河合　聡人
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] Effects of myristate on the induced circular dichroism spectra of aripiprazole bound to human serum albumin: A structural-chemical investigation2022
- Author(s)
  小田切　優樹、平田　憲史郎、河合　聡人、Victor　Tuan　Giam　Chuang、櫻間　啓基、西　弘二、山崎　啓之
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] アルブミンを利用した脂肪酸修飾ピラルビシンナノ粒子の調製とリポソームへの応用2022
- Author(s)
  長谷川　喬史、月川　健士、西　弘二、井本　修平、田口　和明、小田切　優樹、山崎　啓之
- Organizer
  第39回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2021
- Author(s)
  西弘二、別府拓豪、井本修平、異島優、月川健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導メカニズムの解明2021
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞におけるニトロ化フェニル酪酸のオートファジー阻害効果2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞におけるニトロ化フェニル酪酸の細胞死誘導メカニズムの解明と抗腫瘍効果の評価2021
- Author(s)
  別府拓豪, 西弘二, 井本修平, 異島優, 月川健士, 小田切優樹, 山崎啓之
- Organizer
  日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞におけるニトロ化ナテグリニドの細胞死誘導効果2021
- Author(s)
  西弘二、別府拓豪、井本修平、異島優、月川健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導メカニズムの解明2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島優、月川健士、小田切優樹、山崎啓之
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] 酸性環境応答性を有するアルブミン結合型抗がん剤の作製と抗がん効果2021
- Author(s)
  月川健士、井本修平、西弘二、堤敏彦、横山祥子、小田切優樹、山崎啓之
- Organizer
  第37回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] 肝マクロファージを標的としたレドックス応答性ナノラジカルスカベンジャーの開発と肝疾患治療への応用2021
- Author(s)
  安田健吾, 木下遼, 前田仁志, 皆吉勇紀, 櫻木美菜, 山崎啓之, 水田夕稀, 異島優, 石田竜弘, 渡邊博志, 丸山徹
- Organizer
  日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞におけるニトロ化フェニル酪酸の細胞死誘導メカニズムの解明と抗腫瘍効果の評価2021
- Author(s)
  別府拓豪、西弘二、井本修平、異島　優、月川　健士、小田切優樹、山崎啓之
- Organizer
  第38回日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] 慢性腎不全患者におけるアリピプラゾールの血漿タンパク質結合能評価2021
- Author(s)
  平田憲史郎, 池田徳典, 渡邊博志, 丸山徹, 田中元子, 内田友二, 櫻間啓基, 西弘二, 山崎啓之, 小田切優樹
- Organizer
  日本薬学会九州山口支部大会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] Investigation of the interaction between 4-phenylbutyric acid and cyclodextrins2021
- Author(s)
  Kindness Commey、中武灯、西　弘二、月川健士、庵原　大輔、平山　文俊、小田切優樹、山崎啓之
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] マクロファージ及び線維芽細胞を標的可能なレドックス応答性ナノラジカルスカベンジャーの開発と肝疾患治療への応用2021
- Author(s)
  安田健吾、木下遼、前田仁志、皆吉勇紀、櫻木美奈、水田夕稀、山崎啓之、異島優、石田竜弘、渡邊博志、丸山徹
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-20K06995
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2020
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2020
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] アルブミンとの混合噴霧乾燥によるプラジカンテル粒子の調製と溶出性・経口吸収性評価2020
- Author(s)
  山崎啓之、田口和明、西弘二、小田切優樹、瀬尾量
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ヒト膵がん細胞に対するニトロ化フェニル酪酸の細胞死誘導効果2020
- Author(s)
  別府拓豪、西弘二、井本修平、小田切優樹、山崎啓之
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07193
[Presentation] 脱溶媒法によるラクトフェリンナノ粒子に与える調製パラメーターの影響2020
- Author(s)
  田口和明、橋本麻衣、中山真雪、榎木裕紀、西弘二、松元一明、瀬尾量、小田切優樹、山崎啓之
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 血清アルブミンを活用した環境応答性高分子化抗がん剤の作製と評価2019
- Author(s)
  月川健士、井本修平、山崎啓之、堤敏彦、横山祥子、小田切優樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 脱溶媒和法により調製したドキソルビシン封入ヒト血清アルブミンナノ粒子の抗腫瘍効果に関する検討2019
- Author(s)
  山崎啓之, 木村虎太郎, 西弘二, 猪原彩希, 大島千佳, 井本修平, 田口和明, 小田切優樹
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] B型肝炎ウイルス新規候補治療薬 4'-CN-2'-deoxyguanosine の急性肝傷害モデルラットにおける体内動態解析2019
- Author(s)
  橋本麻衣、田口和明、井本修平、山崎啓之、満屋裕明、小田切優樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] グレープフルーツのCYP3A活性阻害におよぼすシクロデキストリン処理の影響2019
- Author(s)
  山崎啓之, 小山陽子, 西崎成美, 河津誠太郎, 庵原大輔, 田口和明, 門脇大介, 小田切優樹, 瀬尾量
- Organizer
  第29回日本医療薬学会年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 健常ラット及び出血性ショックラットに対するヘモグロビン小胞体輸血が肝チトクロームP450の発現量に与える影響2019
- Author(s)
  小田切優樹、得能正裕、山崎啓之、大槻純男、酒井宏水、田口和明
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ヒトα1-酸性糖タンパク質に対するアリピプラゾールの結合特性評価2019
- Author(s)
  西弘二、櫻間啓基、井本修平、山崎啓之、小田切優樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ドキソルビシン封入ヒト血清アルブミンナノ粒子のin vitroおよびin vivo機能評価2019
- Author(s)
  山崎啓之、木村虎太郎、西弘二、田口和明、小田切優樹
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ヒト血清アルブミン分子上サイトⅡへのアリピプラゾール結合における塩素原子の重要性2018
- Author(s)
  櫻間啓基、井本修平、河合聡人、田口和明、瀬尾、小田切優樹、山崎啓之
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 脱溶媒和法により調製したドキソルビシン封入ヒト血清アルブミンナノ粒子の機能評価2018
- Author(s)
  山崎啓之、木村虎太郎、田口和明、中村秀明、原武衛、小田切優樹
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 各種病態時におけるダプトマイシンのタンパク結合変化のin vitroでの予測2018
- Author(s)
  山崎啓之、櫻間啓基、田口和明、瀬尾量、小田切優樹
- Organizer
  日本薬剤学会　第33年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ヘモグロビン小胞体大量投与が薬物の体内動態に与える影響2018
- Author(s)
  西川紗綾、得能正裕、田口和明、山崎啓之、酒井宏水、小田切優樹
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 抗がん剤用DDSキャリアとしてのアルブミンナノ粒子の有用性評価2018
- Author(s)
  山崎啓之, 木村虎太郎, 中村秀明, 原武衛, 田口和明, 小田切優樹
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] パクリタキセル－アルブミン内包リポソームの膵臓がん治療への応用2018
- Author(s)
  田口和明、岡本侑子、櫻木美菜、山崎啓之、小田切優樹
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 一酸化炭素結合型ヘモグロビン小胞体の抗炎症作用機序の解明と急性膵炎治療への応用2018
- Author(s)
  田口和明、永尾紗理、前田仁志、酒井宏水、山崎啓之、丸山徹、小田切優樹
- Organizer
  日本薬剤学会　第33年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ダプトマイシンのタンパク結合特性と生体内変動因子の影響2017
- Author(s)
  櫻間啓基、田口和明、瀬尾量、小田切優樹、山崎啓之
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] パクリタキセル-アルブミン内包リポソームの作製と有用性評価2017
- Author(s)
  岡本侑子、田口和明、櫻木美菜、山崎啓之、小田切優樹
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 抗がん剤封入ヒト血清アルブミンナノ粒子の物性評価とin vitro評価2017
- Author(s)
  木村虎太郎、山崎啓之、田口和明、中村秀明、原武衛、小田切優樹
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 抗がん剤封入アルブミンナノ粒子の調製とin vitro評価2017
- Author(s)
  山崎桃子、木村虎太郎、山崎啓之、田口和明、中村秀明、原武衛、小田切優樹
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 急性膵炎に対する一酸化炭素結合型ヘモグロビン小胞体の有用性評価2017
- Author(s)
  田口和明、永尾紗理、酒井宏水、山崎啓之、丸山徹、小田切優樹
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] ヘモグロビン小胞体の難治性炎症疾患治療薬としての応用使用2017
- Author(s)
  田口和明，永尾紗理，酒井宏水，山崎啓之，丸山　徹，小田切優樹
- Organizer
  第24回日本血液代替物学会年次大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] Antioxidative property of recombinant human serum albumin containing 3 copies of domain I in vitro.2017
- Author(s)
  Koji Nishi, Sadaharu Matsushita, Yasunori Iwao, Yu Ishima, Hiroshi Watanabe, Kazuaki Taguchi, Keishi Yamasaki, Toru Maruyama, Masaki Otagiri
- Organizer
  AFPS2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] アリピプラゾールのヒト血清アルブミン結合に関する検討2017
- Author(s)
  金森陽子、櫻間啓基、長美友、田口和明、瀬尾量、小田切優樹、山崎啓之
- Organizer
  第34回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] フェニル酪酸ナトリウムの動物種アルブミンへの結合特性評価2017
- Author(s)
  榎田泰介、山崎啓之、田口和明、宮本秀一、小田切優樹
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] Comparative study of sodium 4-phenylbutyrate binding to albumins from different species.2017
- Author(s)
  Keishi Yamasaki, Taisuke Enokida, Akito Kawai, Shuichi Miyamoto, Kazuaki Taguchi, Toru Maruyama, Hakaru Seo, Masaki Otagiri
- Organizer
  AFPS2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] X線結晶構造解析に基づくオクタン酸ナトリウムおよびN-アセチル-L-メチオニンのヒト血清アルブミン安定化機構の解明2017
- Author(s)
  山崎啓之, 河合聡人, 河野陽介, 宮本秀一, 田口和明, 安楽　誠, 小田切優樹
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] 4-フェニル酪酸ナトリウムの血清アルブミン結合における種差2017
- Author(s)
  山崎啓之、榎田泰介、田口和明、宮村重幸、河合聡人、宮本秀一、丸山徹、瀬尾量、小田切優樹
- Organizer
  薬物動態学会第32年会
- Data Source
  KAKENHI-PROJECT-17K08261
[Presentation] In vitro evaluation for antioxidant activities of dietary supplements2009
- Author(s)
  Yamasaki K
- Organizer
  Asian Federation for Pharmaceutical Sciences
- Place of Presentation
  九州大学
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21590054
[Presentation] In vitro evaluation for antioxidant activities of dietary supplements.2009
- Author(s)
  Yamasaki K
- Organizer
  Asian Federation for Pharmaceutical Sciences
- Place of Presentation
  九州大学
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-21590054

1. Nishi Koji (00398249)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 井本修平 (20447189)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. OTAGIRI Masaki (80120145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 異島優 (00457590)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. SEO Hakaru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. KADOWAKI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. WATANABE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MARUYAMA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 河合聡人

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 田口和明

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
11. 前田仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamasaki Keishi 山崎 啓之

YAMASAKI Keishi 山崎 啓之

Research Projects

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Co-Researchers

Development of NO donors with high albumin affinity for treatment of pancreatic cancer

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Development of albumin-binding fatty acid-modified nanoparticles for effective cancer therapyPrincipal Investigator

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Development of albumin-binding nitric oxide donors for treatment of pancreatic cancer

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Development of albumin-coated stealth nanoparticles for effective anticancer therapyPrincipal Investigator

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Development of novel drug delivery system by controlling of albumin disposition in lungPrincipal Investigator

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Study on the serum protein-mediated drug transport in biological membrane interfacePrincipal Investigator

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[Journal Article] Effects of Myristate on the Induced Circular Dichroism Spectra of Aripiprazole Bound to Human Serum Albumin: A Structural?Chemical Investigation2022

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[Journal Article] Novel nitric oxide donor, nitrated phenylbutyrate, induces cell death of human pancreatic cancer cells and suppresses tumor growth of cancer xenografts2022

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[Journal Article] Trimethoxy trityl groups as a potent substituent for anti-cancer cytidine analog prodrugs.2022

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[Journal Article] An in vitro comparative study of the binding of caspofungin and micafungin to plasma proteins.2022

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[Journal Article] Chlorine Atoms of an Aripiprazole Molecule Control the Geometry and Motion of Aripiprazole and Deschloro-aripiprazole in Subdomain IIIA of Human Serum Albumin2022

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[Journal Article] Structural Basis of the Change in the Interaction Between Mycophenolic Acid and Subdomain IIA of Human Serum Albumin During Renal Failure2022

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[Journal Article] Effect of Fatty Acids and Uremic Toxins on the Binding of Nateglinide, an Insulin Secretagogue, to Site II on Human Serum Albumin2022

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[Journal Article] In vitro and in vivo assessment of Atemoya fruit (Annona atemoya) for food-drug interactions.2022

Yamasaki Keishi 山崎啓之

YAMASAKI Keishi 山崎啓之