Kushiyama Akifumi 櫛山暁史

… Alternative Names

KUSHIYAMA Akifumi 櫛山曉史

櫛山曉史クシヤマアキフミ

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Researcher Number	30435820
Other IDs	https://orcid.org/0000-0003-1385-7487
Affiliation (Current)	2025: 明治薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 明治薬科大学, 薬学部, 教授 2016 – 2018: 公益財団法人朝日生命成人病研究所, その他部局等, 教授(移行) 2014 – 2015: 公益財団法人朝日生命成人病研究所, その他部局等, 教授 2011 – 2013: 公益財団法人朝日生命成人病研究所, その他部局等, 准教授 2010: 公益財団法人朝日生命成人病研究所, 准教授 … More 2008 – 2009: The Institute for Adult Diseases, Asahi Life Foundation, その他部局, 准教授 2008: The Institute for Adult Diseases, Asahi Life Foundation, その他部局等, 准教授 2007: The Institute for Adult Diseases, Asahi Life Foundation, その他部局, 准教授 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 56060:Ophthalmology-related / Basic Section 59040:Nutrition science and health science-related / Circulatory organs internal medicine Except Principal Investigator Basic Section 56060:Ophthalmology-related / Basic Section 57030:Conservative dentistry-related / Basic Section 08030:Family and consumer sciences, and culture and living-related
Keywords	Principal Investigator キサンチンオキシダーゼ / 生活習慣病 / マクロファージ / 核酸代謝 / 尿酸代謝 / 尿酸 / ナノ粒子化点眼 / 虚血再灌流障害 / 糖尿病網膜症 / プリン体 … More / CKD / 肥満 / 非アルコール性脂肪肝炎 / 糖尿病 / プリン体代謝異常 / 分子血管病態 / Relmβ / 自然免疫 / NASH モデル / メタボリックシンドローム / インスリン抵抗性 / レジスチン様分子 / 分子血管病態学 / 粥状動脈硬化症 / RELMβ / 血管新生 / 血管内皮機能 / 動脈硬化症 … More Except Principal Investigator ペリサイト / パイロトーシス / 網膜神経血管連関 / 糖尿病網膜症 / 微細炎症 / 脂肪組織 / CCL19 / 動脈硬化 / 高脂肪 / マクロファージ / ccl19 / 血液生化学分析 / アンケート調査 / 食餌中の脂質含量 / 健康寿命 / 体重変化 / 臓器重量 / 遺伝子発現 / 動物実験 / 食の欧米化 / 生化学的分析 / 食物繊維 Less

The role of inflammatory Cell Death (Pyroptosis) in the Pathogenesis of Diabetic Retinopathy and Novel Nanoparticle Eye Drop Therapy
- Principal Investigator
  
  長岡泰司
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Asahikawa Medical College
Overcoming Diabetic Retinopathy through Local Control of Oxidative StressPrincipal Investigator
- Principal Investigator
  
  櫛山暁史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Meiji Pharmaceutical University
歯周病と動脈硬化―微細炎症合併日本人型軽度肥満モデルでの検討
- Principal Investigator
  
  岩下未咲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nagasaki University
  Kyushu University
Potentiality of dietary fiber for healthy longevity
- Principal Investigator
  
  Minami Michiko
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Tokyo Gakugei University
The essence of health disorder caused by purine bodies as the substratesPrincipal Investigator
- Principal Investigator
  
  Kushiyama Akifumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Meiji Pharmaceutical University
Related elucidation of the tissue-specific pudding metabolism state and lifestyle-related diseasePrincipal Investigator
- Principal Investigator
  
  Kushiyama Akifumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
Elucidation of pathogenesis of the onset of lifestyle-related diseases due to oxidative stress derived from diet componentsPrincipal Investigator
- Principal Investigator
  
  Kushiyama Akifumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
The role of resistin-like molecules in natural immune system involving insulin resistance.Principal Investigator
- Principal Investigator
  
  KUSHIYAMA Akifumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
Investigation for the effects of macrophage-derived resistin like molecule on development of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  KUSHIYAMA Akifumi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  公益財団法人朝日生命成人病研究所
   The Institute for Adult Diseases, Asahi Life Foundation
Investigation of roles of resistin like molecule beta in pathogenesis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  KUSHIYAMA Akifumi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases, Asahi Life Foundation

[Book] 最新基礎栄養学2019
- Author(s)
  南　道子、櫛山櫻、篠田粧子、大池秀明、西村直道、佐川まさの、阿部志磨子、江口昭彦、雨海照祥、原一雄
- Total Pages
  194
- Publisher
  医歯薬出版　第９版
- ISBN
  9784263707470
- Data Source
  KAKENHI-PROJECT-19K02314
[Book] 糖尿病の療養指導Q＆A vol.22019
- Author(s)
  櫛山暁史他
- Total Pages
  167
- Publisher
  医歯薬出版株式会社
- ISBN
- Data Source
  KAKENHI-PROJECT-16K09791
[Book] 『ここまで明らかになった！尿酸代謝ワールドと高尿酸血症の病態解明～診療と医学の最前線～』(動脈硬化（尿酸と血管リモデリング）の形成と進展　アテローム性動脈硬化)2015
- Author(s)
  櫛山暁史
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25461372
[Book] 生体の科学2014
- Author(s)
  櫛山暁史
- Publisher
  金原一郎医学医療振興財団
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] Dilation of porcine retinal arterioles to nobiletin, a polymethoxyflavonoid: Roles of nitric oxide and voltage-dependent potassium channel2023
- Author(s)
  Watanabe M, Miyata Y, Ohno A, Yokota H, Takase K, Hanaguri J, Kushiyama A, Yamagami S, Harino S, Nagaoka T
- Journal Title
  
  Exp Eye Res
  
  Volume: 233 Pages: 109548-109548
- DOI
  10.1016/j.exer.2023.109548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Identification of Prescribing Patterns in Hemodialysis Outpatients Taking Multiple Medications.2023
- Author(s)
  Nagano H, Tomori K, Koiwa M, Kobayashi S, Takahashi M, Makabe H, Okada H, Kushiyama A
- Journal Title
  
  Pharmacy (Basel)
  
  Volume: 11 Issue: 2 Pages: 43-43
- DOI
  10.3390/pharmacy11020043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Comparison of Weight Reduction, Change in Parameters and Safety of a Very Low Carbohydrate Diet in Comparison to a Low Carbohydrate Diet in Obese Japanese Subjects with Metabolic Disorders.2023
- Author(s)
  Kikuchi T, Kushiyama A, Yanai M, Kashiwado C, Seto T, Kasuga M.
- Journal Title
  
  Nutrients.
  
  Volume: 15 Issue: 6 Pages: 1342-1342
- DOI
  10.3390/nu15061342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Renally inappropriate medications in elderly outpatients and inpatients with an impaired renal function.2023
- Author(s)
  Kobayashi S, Sugama N, Nagano H, Takahashi M, Kushiyama A
- Journal Title
  
  Hosp Pract
  
  Volume: 51 Issue: 2 Pages: 76-81
- DOI
  10.1080/21548331.2023.2173412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] シームレスな「人体の構造と機能」の学習を実現するための医療系大学入学前後の学習項目の調査2023
- Author(s)
  本間典子・櫛山櫻・南道子
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 74 Pages: 418-428
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Analysis of Adverse Events of Cholinesterase Inhibitors and NMDA Receptor Antagonists on Arrhythmias Using the Japanese Adverse Drug Event Report Database2023
- Author(s)
  Kobayashi S, Sugama N, Nagano H, Miyamori A, Takahashi M, Kushiyama A.
- Journal Title
  
  Drugs Real World Outcomes
  
  Volume: 10 Issue: 2 Pages: 321-329
- DOI
  10.1007/s40801-023-00362-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells2023
- Author(s)
  Akasaka Y, Hasei S, Ohata Y, Kanna M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Ono H, Matsubara A, Hinata N, Asano T, Yamamotoya T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24(21) Issue: 21 Pages: 16011-16011
- DOI
  10.3390/ijms242116011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08655, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-23K27650
[Journal Article] A pilot study of diabetic retinopathy in a porcine model of maturity onset diabetes of the young type 3 (MODY3)2023
- Author(s)
  Takase K, Yokota H, Ohno A, Watanabe M, Kushiyama A, Kushiyama S, Yamagami S, Nagaoka T
- Journal Title
  
  Exp Eye Res.
  
  Volume: 227 Pages: 109379-109379
- DOI
  10.1016/j.exer.2022.109379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-22K09822, KAKENHI-PROJECT-20K09835
[Journal Article] The Effect of Sodium-Dependent Glucose Cotransporter 2 Inhibitor Tofogliflozin on Neurovascular Coupling in the Retina in Type 2 Diabetic Mice2022
- Author(s)
  Hanaguri Junya、Yokota Harumasa、Kushiyama Akifumi、Kushiyama Sakura、Watanabe Masahisa、Yamagami Satoru、Nagaoka Taiji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 3 Pages: 1362-1362
- DOI
  10.3390/ijms23031362
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Synergistic deterioration of prognosis associated with decreased grip strength and hyporesponse to erythropoiesis-stimulating agents in patients undergoing hemodialysis2022
- Author(s)
  Kobayashi S, Tanaka K, Hoshino J, Hara S, Kushiyama A, Tanaka Y, Motonishi S, Sakai K, Ozawa T.
- Journal Title
  
  Ren Fail
  
  Volume: 44 Issue: 1 Pages: 1801-1810
- DOI
  10.1080/0886022x.2022.2106873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Beneficial Effect of Long-Term Administration of Supplement With Trapa Bispinosa Roxb. and Lutein on Retinal Neurovascular Coupling in Type 2 Diabetic Mice2022
- Author(s)
  Hanaguri Junya、Yokota Harumasa、Kushiyama Akifumi、Kushiyama Sakura、Watanabe Masahisa、Yamagami Satoru、Nagaoka Taiji
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 13 Pages: 788034-788034
- DOI
  10.3389/fphys.2022.788034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Metabolism-dependent Vascular Pathophysiology in Adult Diseases2022
- Author(s)
  Kushiyama Akifumi、Takahashi Masahiro、Kushiyama Sakura、Kikuchi Takako、Asano Tomoichiro
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 5 Pages: 465-471
- DOI
  10.1248/yakushi.21-00176-3
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Concomitant Spatiotemporal Electrogram Dispersion and Low Voltage During Atrial Fibrillation Is Associated With Refractory Atrial Fibrillation After Catheter Ablation2022
- Author(s)
  Kawaji T, Aizawa T, Hojo S, Kushiyama A, Yaku H, Nakatsuma K, Kaneda K, Kato M, Yokomatsu T, Miki S
- Journal Title
  
  Circ Arrhythm Electrophysiol
  
  Volume: 15 Issue: 5 Pages: 340-340
- DOI
  10.1161/circep.121.010707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Recent Advances in the Studies of Metabolic Syndromes and Applications to the Development of New Drugs2022
- Author(s)
  Kushiyama Akifumi、Nakatsu Yusuke
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 142 Issue: 5 Pages: 447-448
- DOI
  10.1248/yakushi.21-00176-F
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2022-05-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases2022
- Author(s)
  Yamamotoya Takeshi、Hasei Shun、Akasaka Yasuyuki、Ohata Yukino、Nakatsu Yusuke、Kanna Machi、Fujishiro Midori、Sakoda Hideyuki、Ono Hiraku、Kushiyama Akifumi、Misawa Hidemi、Asano Tomoichiro
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 1966-1966
- DOI
  10.1038/s41598-022-05884-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K19380
[Journal Article] Effect of prorenin peptide vaccine on the early phase of diabetic retinopathy in a murine model of type 2 diabetes2022
- Author(s)
  Yokota Harumasa、Hayashi Hiroki、Hanaguri Junya、Yamagami Satoru、Kushiyama Akifumi、Nakagami Hironori、Nagaoka Taiji
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 1 Pages: e0262568-e0262568
- DOI
  10.1371/journal.pone.0262568
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K09835
[Journal Article] Different Kinetics of Activated Clotting Time Among Uninterrupted Oral Anticoagulants During Catheter Ablation Procedure.2022
- Author(s)
  Kawaji T, Morimoto T, Aizawa T, Hojo S, Kushiyama A, Yaku H, Nakatsuma K, Kaneda K, Kato M, Yokomatsu T, Miki S, Kimura T.
- Journal Title
  
  J Clin Pharmacol.
  
  Volume: 62 Issue: 6 Pages: 792-800
- DOI
  10.1002/jcph.2018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Fenofibrate Nano-Eyedrops Ameliorate Retinal Blood Flow Dysregulation and Neurovascular Coupling in Type 2 Diabetic Mice2022
- Author(s)
  Hanaguri Junya、Nagai Noriaki、Yokota Harumasa、Kushiyama Akifumi、Watanabe Masahisa、Yamagami Satoru、Nagaoka Taiji
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 2 Pages: 384-384
- DOI
  10.3390/pharmaceutics14020384
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] 若年層の食の課題と家庭科の食の授業2021
- Author(s)
  斎藤美奈子、櫛山櫻、南道子
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 72 Pages: 323-338
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] 高等学校家庭科における食生活への気づきをもたらす献立作成学習2021
- Author(s)
  斎藤美奈子、櫛山櫻、南道子
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 73 Pages: 346-37
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Prolyl isomerase Pin1 interacts with adipose triglyceride lipase and negatively controls both its expression and lipolysis2021
- Author(s)
  Yusuke Nakatsu, Takeshi Yamamotoya, Mizuki Okumura, Tetsuhiro Ishii, Mayu Kanamoto, Miki Naito, Mikako Nakanishi, Shunya Aoyama, Yasuka Matsunaga, Akifumi Kushiyama, Hideyuki Sakoda, Midori Fujishiro, Hiraku Ono, Tomoichiro Asano
- Journal Title
  
  Metabolism
  
  Volume: 15 Pages: 154459-154459
- DOI
  10.1016/j.metabol.2020.154459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-18K08502
[Journal Article] 運動習慣の有無による食品と栄養素の摂取状況2021
- Author(s)
  渕上美咲、南道子、櫛山櫻
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 72 Pages: 339-350
- NAID
  120007046367
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Synergistic association of the copper/zinc ratio under inflammatory conditions with diabetic kidney disease in patients with type 2 diabetes: The Asahi Diabetes Complications Study2021
- Author(s)
  Takao Toshiko、Yanagisawa Hiroyuki、Suka Machi、Yoshida Yoko、Onishi Yukiko、Tahara Tazu、Kikuchi Takako、Kushiyama Akifumi、Anai Motonobu、Takahashi Kazuyuki、Wakabayashi Sugawa Sayaka、Yamazaki Hiroki、Kawazu Shoji、Iwamoto Yasuhiko、Noda Mitsuhiko、Kasuga Masato
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 13 Issue: 2 Pages: 299
- DOI
  10.1111/jdi.13659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Carnosic Acid and Carnosol Activate AMPK, Suppress Expressions of Gluconeogenic and Lipogenic Genes, and Inhibit Proliferation of HepG2 Cells2021
- Author(s)
  Hasei S, Yamamotoya T, Nakatsu Y, Ohata Y, Itoga S, Nonaka Y, Matsunaga Y, Sakoda H, Fujishiro M, Kushiyama A, Asano T.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 8 Pages: 4040-4040
- DOI
  10.3390/ijms22084040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08580
[Journal Article] 拡張現実（AR）技術を用いた人体構造の理解を深めるための三次元教材の開発とその有効性2021
- Author(s)
  本間典子、櫛山櫻、南　道子
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 73 Pages: 239-254
- NAID
  120007184524
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Quantitative sonographic assessment of quadriceps muscle thickness for fall injury prediction in patients undergoing maintenance hemodialysis: an observational cohort study2021
- Author(s)
  Sai A, Tanaka K, Ohashi Y, Kushiyama A, Tanaka Y, Motonishi S, Sakai K, Hara S, Ozawa T.
- Journal Title
  
  BMC Nephrol
  
  Volume: 22 Issue: 1 Pages: 191-191
- DOI
  10.1186/s12882-021-02347-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] 学校現場における栄養に関する教育内容の変遷と課題―学習指導要領および教科書における食物繊維の記載に着目してー2021
- Author(s)
  櫛山櫻、斎　麻倫、南　道
- Journal Title
  
  東京学芸大学紀要
  
  Volume: 73 Pages: 363-374
- Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Pathological Role of Pin1 in the Development of DSS-Induced Colitis2021
- Author(s)
  Matsunaga Yasuka、Hasei Shun、Yamamotoya Takeshi、Honda Hiroaki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Ito Hisanaka、Okabe Takayoshi、Asano Tomoichiro、Nakatsu Yusuke
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 5 Pages: 1230-1230
- DOI
  10.3390/cells10051230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K22546, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-19H03693, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] Characteristics Associated with Early Worsening of Retinopathy in Patients with Type 2 Diabetes Diagnosed with Retinopathy at Their First Visit: A Retrospective Observational Study2021
- Author(s)
  Sugawa Sayaka Wakabayashi、Yoshida Yoko、Hikima Yusuke、Sato Haruhiko、Shimada Akira、Noda Mitsuhiko、Kushiyama Akifumi
- Journal Title
  
  Journal of Diabetes Research
  
  Volume: 2021 Pages: 1-9
- DOI
  10.1155/2021/7572326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes2021
- Author(s)
  Fujishiro Midori、Ishihara Hisamitsu、Ogawa Katsuhiko、Murase Takayo、Nakamura Takashi、Watanabe Kentaro、Sakoda Hideyuki、Ono Hiraku、Yamamotoya Takeshi、Nakatsu Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 8 Pages: 1052-1052
- DOI
  10.3390/biomedicines9081052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-20K08918, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-21K08580
[Journal Article] Decline in renal function associated with cardiovascular autonomic neuropathy positively coordinated with proteinuria in patients with type?2 diabetes2021
- Author(s)
  Muramatsu Taichi、Takahashi Masahiro、Kakinuma Rena、Sato Tomoyo、Yamamoto Mitsuyo、Akazawa Manabu、Tanaka Kentaro、Kikuchi Takako、Kushiyama Akifumi
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 13 Issue: 1 Pages: 102-111
- DOI
  10.1111/jdi.13625
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Retinal blood flow dysregulation precedes neural retinal dysfunction in type 2 diabetic mice2021
- Author(s)
  Hanaguri Junya、Yokota Harumasa、Watanabe Masahisa、Yamagami Satoru、Kushiyama Akifumi、Kuo Lih、Nagaoka Taiji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18401-18401
- DOI
  10.1038/s41598-021-97651-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K02314
[Journal Article] Prolyl isomerase Pin1 in metabolic reprogramming of cancer cells2020
- Author(s)
  Nakatsu Yusuke、Yamamotoya Takeshi、Ueda Koji、Ono Hiraku、Inoue Masa-Ki、Matsunaga Yasuka、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Matsubara Akio、Asano Tomoichiro
- Journal Title
  
  Cancer Letters
  
  Volume: 470 Pages: 106-114
- DOI
  10.1016/j.canlet.2019.10.043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-19K08982, KAKENHI-PROJECT-20H03732
[Journal Article] Effect of postprandial hyperglycemia at clinic visits on the incidence of retinopathy in patients with type?2 diabetes: An analysis using real‐world long‐term follow‐up data2020
- Author(s)
  Takao Toshiko、Takahashi Kazuyuki、Yoshida Yoko、Kushiyama Akifumi、Onishi Yukiko、Tahara Tazu、Shimmei Asuka、Kikuchi Takako、Suka Machi、Yanagisawa Hiroyuki、Iwamoto Yasuhiko、Kasuga Masato
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 4 Pages: 930-937
- DOI
  10.1111/jdi.13194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784
[Journal Article] Comparisons between dipeptidyl peptidase-4 inhibitors and other classes of hypoglycemic drugs using two distinct biomarkers of pancreatic beta-cell function: A meta-analysis2020
- Author(s)
  Takahashi Masahiro、Shibasaki Misa、Echizen Hirotoshi、Kushiyama Akifumi
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 7 Pages: e0236603-e0236603
- DOI
  10.1371/journal.pone.0236603
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784
[Journal Article] Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice2019
- Author(s)
  Inoue Masa-Ki、Matsunaga Yasuka、Nakatsu Yusuke、Yamamotoya Takeshi、Ueda Koji、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Iwashita Misaki、Sano Tomomi、Nishimura Fusanori、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Asano Tomoichiro
- Journal Title
  
  Diabetology & Metabolic Syndrome
  
  Volume: 11 Issue: 1 Pages: 57-57
- DOI
  10.1186/s13098-019-0454-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150
[Journal Article] Treatment of two mitochondrial disease patients with a combination of febuxostat and inosine that enhances cellular ATP2019
- Author(s)
  Kamatani Naoyuki、Kushiyama Akifumi、Toyo-oka Licht、Toyo-oka Teruhiko
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 64 Issue: 4 Pages: 351-353
- DOI
  10.1038/s10038-018-0558-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Journal Article] Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice2019
- Author(s)
  Mizuno Yu、Yamamotoya Takeshi、Nakatsu Yusuke、Ueda Koji、Matsunaga Yasuka、Inoue Masa-Ki、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Kikuchi Takako、Takahashi Masahiro、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 19 Pages: 4680-4680
- DOI
  10.3390/ijms20194680
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-19K11784, KAKENHI-PROJECT-19K17986, KAKENHI-PROJECT-17K16150
[Journal Article] Characteristics and Early Hypoglycemic Medications of Patients at Risk of Progression to Type 2 Diabetes in Japan: A Retrospective Cohort Study of Health Checkup and Claims Data2019
- Author(s)
  Kanai Norihito、Shono Aiko、Kushiyama Akifumi、Akazawa Manabu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 12 Pages: 2016-2023
- DOI
  10.1248/bpb.b19-00505
- NAID
  130007754618
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784
[Journal Article] Association of gait speed and grip strength with risk of cardiovascular events in patients on haemodialysis: a prospective study2019
- Author(s)
  Kuki Atsumi、Tanaka Kentaro、Kushiyama Akifumi、Tanaka Yoshihide、Motonishi Shuta、Sugano Yasuji、Furuya Toru、Ozawa Takashi
- Journal Title
  
  BMC Nephrology
  
  Volume: 20 Issue: 1
- DOI
  10.1186/s12882-019-1370-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11784
[Journal Article] Alpha-Blockers As Colorectal Cancer Chemopreventive: Findings from a Case?Control Study, Human Cell Cultures, and In Vivo Preclinical Testing2019
- Author(s)
  Suzuki Nobumi、Niikura Ryota、Ihara Sozaburo、Hikiba Yohko、Kinoshita Hiroto、Higashishima Naoko、Hayakawa Yoku、Yamada Atsuo、Hirata Yoshihiro、Nakata Ryo、Okamoto Makoto、Sano Munetaka、Kushiyama Akifumi、Ichinose Mari、Woods Susan L.、Worthley Daniel、Iwamoto Yasuhiko、Koike Kazuhiko
- Journal Title
  
  Cancer Prevention Research
  
  Volume: 12 Issue: 3 Pages: 185-194
- DOI
  10.1158/1940-6207.capr-18-0288
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09347, KAKENHI-PROJECT-18K07933, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K15928, KAKENHI-PROJECT-19K17478
[Journal Article] Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation2019
- Author(s)
  Ueda Koji、Nakatsu Yusuke、Yamamotoya Takeshi、Ono Hiraku、Inoue Yuki、Inoue Masa-Ki、Mizuno Yu、Matsunaga Yasuka、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Takahashi Shin-Ichiro、Matsubara Akio、Asano Tomoichiro
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 17 Pages: 1637-1648
- DOI
  10.18632/oncotarget.26691
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-25221204
[Journal Article] Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice:2019
- Author(s)
  Mizuno Y, Yamamotoya T, Nakatsu Y, Ueda K, Matsunaga Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kikuchi T, Takahashi M, Morii K, Sasaki Kg Masaki T, Asano T and Kushiyama A.
- Journal Title
  
  Int J Mol Sci,
  
  Volume: 20 Pages: 1-12
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02314
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications2018
- Author(s)
  Okubo Hirofumi、Kushiyama Akifumi、Nakatsu Yusuke、Yamamotoya Takeshi、Matsunaga Yasuka、Fujishiro Midori、Sakoda Hideyuki、Ohno Haruya、Yoneda Masayasu、Asano Tomoichiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 10 Pages: 3064-3064
- DOI
  10.3390/ijms19103064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model2018
- Author(s)
  Inoue Masa-Ki、Yamamotoya Takeshi、Nakatsu Yusuke、Ueda Koji、Inoue Yuki、Matsunaga Yasuka、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Suzuki Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 12 Pages: 3967-3967
- DOI
  10.3390/ijms19123967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages2018
- Author(s)
  Yamazaki Hiroki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Yamamotoya Takeshi、Nakatsu Yusuke、Kikuchi Takako、Kaneko Sunao、Tanaka Hirotoshi、Asano Tomoichiro
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2018 Pages: 1-12
- DOI
  10.1155/2018/3062319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-17K16158, KAKENHI-PROJECT-16H05330, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Serum uric acid is an independent predictor of new-onset diabetes after living-donor kidney transplantation2018
- Author(s)
  Tanaka Kentaro、Sakai Ken、Kushiyama Akifumi、Hara Shigeko、Hattori Masakazu、Ohashi Yasushi、Muramatsu Masaki、Kawamura Takeshi、Shishido Seiichiro、Aikawa Atsushi
- Journal Title
  
  Renal Replacement Therapy
  
  Volume: 4 Issue: 1
- DOI
  10.1186/s41100-018-0169-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Journal Article] Development of Pin1 inhibitors and their potential as therapeutic agents.2018
- Author(s)
  Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.
- Journal Title
  
  Curr Med Chem
  
  Volume: - Issue: 20 Pages: 1-1
- DOI
  10.2174/0929867325666181105120911
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09791
[Journal Article] Gut microbiota as a　therapeutic target for metabolic disorders.2018
- Author(s)
  Okubo H, Nakatsu Y, Kushiyama A, Yamamotoya T, Matsunaga Y, Inoue MK,　Fujishiro M, Sakoda H, Ohno H, Yoneda M, Ono H, Asano T.
- Journal Title
  
  Curr Med Chem.
  
  Volume: 25 Issue: 9 Pages: 984-1001
- DOI
  10.2174/0929867324666171009121702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K19538, KAKENHI-PROJECT-18K08502
[Journal Article] Gastrointestinal symptom prevalence depends on disease duration and gastrointestinal region in type 2 diabetes mellitus2017
- Author(s)
  Fujishiro M, Kushiyama A, Yamazaki H, Kaneko S, Koketsu Y, Yamamotoya T, Kikuchi T, Sakoda H, Suzuki R, Kadowaki T
- Journal Title
  
  World J Gastroenterol
  
  Volume: 23 Issue: 36 Pages: 6694
- DOI
  10.3748/wjg.v23.i36.6694
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150
[Journal Article] Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-13432-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.2017
- Author(s)
  Yusuke Nakatsu, Hiroki Kokubo, Batmunkh Bumdelger, Masao Yoshizumi, Takeshi Yamamotoya, Yasuka Matsunaga, Koji Ueda, Yuki Inoue, Masa-Ki Inoue, Midori Fujishiro, Akifumi Kushiyama, Hiraku Ono, Hideyuki Sakoda, and Tomoichiro Asano
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18(8) Issue: 8 Pages: 1704-1717
- DOI
  10.3390/ijms18081704
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08443, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion2017
- Author(s)
  Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T.
- Journal Title
  
  J Biol Chem.
  
  Volume: 292 Issue: 28 Pages: 11886-11895
- DOI
  10.1074/jbc.m117.780726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Glial fibrillary acidic protein (GFAP) is a novel biomarker for the prediction of autoimmune diabetes2017
- Author(s)
  Pang Z, Kushiyama A, Sun J, Kikuchi T, Yamazaki H, Iwamoto Y, Koriyama H, Yoshida S, Shimamura M, Higuchi M, Kawano T, Takami Y, Rakugi H, Morishita R, Nakagami H.
- Journal Title
  
  FASEB J.
  
  Volume: 31 Issue: 9 Pages: 4053
- DOI
  10.1096/fj.201700110r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09791
[Journal Article] Epicatechin downregulates adipose tissue CCL19 expression and thereby ameliorates diet-induced obesity and insulin resistance.2017
- Author(s)
  Sano T et al.
- Journal Title
  
  Nutr Metab Cardiovasc Dis
  
  Volume: 27 Issue: 3 Pages: 249-259
- DOI
  10.1016/j.numecd.2016.11.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H07067, KAKENHI-PROJECT-26463136, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11551, KAKENHI-PROJECT-16K11503
[Journal Article] Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.2016
- Author(s)
  Kushiyama A, Nakatsu Y, Matsunaga Y, Yamamotoya T, Mori K, Ueda K, Inoue Y, Sakoda H, Fujishiro M, Ono H, Asano T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2016 Pages: 8603164-8603164
- DOI
  10.1155/2016/8603164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K09791
[Journal Article] C-Peptide Level in Fasting Plasma and Pooled Urine Predicts HbA1c after Hospitalization in Patients with Type 2 Diabetes Mellitus.2016
- Author(s)
  Sonoda R, Tanaka K, Kikuchi T, Onishi Y, Takao T, Tahara T, Yoshida Y, Suzawa N, Kawazu S, Iwamoto Y, Kushiyama A.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 2 Pages: e0147303-e0147303
- DOI
  10.1371/journal.pone.0147303
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-16K09791
[Journal Article] Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.2016
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mori K, Sakoda H, Fujishiro M, Ono H, Kushiyama A, Asano T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 17 (9) Issue: 9 Pages: 1495-1495
- DOI
  10.3390/ijms17091495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H06427, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791
[Journal Article] Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.2016
- Author(s)
  Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20157-20157
- DOI
  10.1038/srep20157
- NAID
  120006796541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26860735, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16K09791
[Journal Article] Prediction of the effect on antihyperglycaemic action of sitagliptin by plasma active form glucagon-like peptide-1.2016
- Author(s)
  Kushiyama A, Kikuchi T, Tanaka K, Tahara T, Takao T, Onishi Y, Yoshida Y, Kawazu S, Iwamoto Y.
- Journal Title
  
  World J Diabetes
  
  Volume: 7 Issue: 11 Pages: 230-238
- DOI
  10.4239/wjd.v7.i11.230
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09791
[Journal Article] Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling.2015
- Author(s)
  Sano T, Iwashita M, Nagayasu S, Yamashita A, Shinjo T, Hashikata A, Asano T, Kushiyama A, Ishimaru N, Takahama Y, Nishimura F
- Journal Title
  
  Obesity
  
  Volume: 23 Issue: 7 Pages: 1460-1471
- DOI
  10.1002/oby.21127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15676, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26861816, KAKENHI-PROJECT-25293425
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang S, Nakatsu Y, Seno Y, Fujishiro M, Sakoda H, Kushiyama A, Mori K, Matsunaga Y, Yamamotoya T, Kamata H, Asano T.
- Journal Title
  
  Diabetol Metab Syndr.
  
  Volume: 7 Issue: 1 Pages: 104-104
- DOI
  10.1186/s13098-015-0102-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yasuka Matsunaga, Haruya Ohno, Masayasu Yoneda, Hideaki Kamata, Takanori Shinjo, Misaki Iwashita, Fusanori Nishimura, and Tomoichiro Asano
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume: 308 Issue: 2 Pages: 151-158
- DOI
  10.1152/ajpgi.00198.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 309(1) Issue: 1 Pages: G42-G51
- DOI
  10.1152/ajpgi.00443.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y, Matsunaga Y, Fukushima T, Tsuchiya Y, Sakoda H, Fujishiro M, Yamamotoya T, Kamata H, Matsubara A, Asano T.
- Journal Title
  
  PLoS One.
  
  Volume: 10 (6) Issue: 6 Pages: e0127467-e0127467
- DOI
  10.1371/journal.pone.0127467
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10591, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice2015
- Author(s)
  Ｓhinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F, Asano T.
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: ７ Issue: 1 Pages: 50-50
- DOI
  10.1186/s13098-015-0047-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15351, KAKENHI-PROJECT-25461372
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga Y, Nakatsu Y, Fukushima T, Okubo H, Iwashita M, Sakoda H, Fujishiro M, Yamamotoya T, Kushiyama A, Takahashi S, Tsuchiya Y, Kamata H, Tokunaga F, Iwai K, Asano T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2015 Issue: 1 Pages: 125380-125380
- DOI
  10.1155/2015/125380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670154, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-25253019
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 309(3) Issue: 3 Pages: E214-E223
- DOI
  10.1152/ajpendo.00553.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15K15351, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit2015
- Author(s)
  Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24255-24266
- DOI
  10.1074/jbc.m115.658559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-26660287, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] Role of elevated serum uric acid levels at the onset of overt nephropathy in the risk for renal function decline in patients with type 2 diabetes2014
- Author(s)
  Kentaro Tanaka, Shigeko Hara, Masakazu Hattori, Ken Sakai, Yukiko Onishi, Yoko Yoshida, Shoji Kawazu
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 1 Pages: 98-104
- DOI
  10.1111/jdi.12243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] Linking uric acid metabolism to diabetic complications.2014
- Author(s)
  Kushiyama A, Tanaka K, Hara S, Kawazu S.
- Journal Title
  
  World J Diabetes
  
  Volume: 15 Issue: 6 Pages: 787-795
- DOI
  10.4239/wjd.v5.i6.787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] 尿酸代謝と生活習慣病の新知見2014
- Author(s)
  櫛山　暁史
- Journal Title
  
  生体の科学
  
  Volume: 65 Pages: 11-11
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] he Inflammation-lipocalin2 axis may contribute to the development of chronic kidney disease.2014
- Author(s)
  Hashikata A, Yamashita A, Suzuki S, Nagayasu S, Shinjo T, Taniguchi A, Fukushima M, Nakai Y, Nin K, Watanabe N, Asano T, Abiko Y, Kushiyama A, Nagasaka S, Nishimura F.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: ２９ Issue: 3 Pages: 611-618
- DOI
  10.1093/ndt/gft449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293425, KAKENHI-PROJECT-25461372
[Journal Article] A 20-year trend of increasing obesity in young patients with poorly controlled type 2 diabetes at first diagnosis in urban Japan2013
- Author(s)
  Kushiyama A
- Journal Title
  
  J Diabet Invest.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047
[Journal Article] Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development2013
- Author(s)
  Kushiyama A
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice2013
- Author(s)
  Iwashita M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima T, Kumamoto S, Shinjo T, Kamata H, Nishimura F, Asano T
- Journal Title
  
  Adipocyte
  
  Volume: 2(1) Issue: 1 Pages: 28-32
- DOI
  10.4161/adip.21837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24792328
[Journal Article] Twenty-year trend of increasing obesity in young patients with poorly controlled type 2 diabetes at first diagnosis in urban Japan.2013
- Author(s)
  Kushiyama A, Yoshida Y, Kikuchi T, Suzawa N, Yamamoto M, Tanaka K, Okayasu M, Tahara T, Takao T, Onishi Y, Kawazu S.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 4 Issue: 6 Pages: 540-545
- DOI
  10.1111/jdi.12090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] Integrator complex plays anessential role inadipose differentiation2013
- Author(s)
  Otani Y, Nakatsu Y, Sakoda H, Fukushima T, Fujishiro M, Kushiyama A, Okubo H, Tsuchiya Y, Ohno H, Takahashi S, Nishimura F, Kamata H, Katagiri H, Asano T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 434 Issue: 2 Pages: 197-202
- DOI
  10.1016/j.bbrc.2013.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928
[Journal Article] Lactobacillus casei strain Shirota protects against non-alcoholic steatohepatitis development in a rodent model2013
- Author(s)
  Okubo H, Sakoda H, Kushiyama A, Fujishiro M, Nakatsu Y, Fukushima T, Matsunaga Y, Kamata H, Asahara T, Yoshida Y, Chonan O, Iwashita M, Nishimura F, Asano T
- Journal Title
  
  American Journal Physiolgy-Gastrointestinal and Liver Physiogy
  
  Volume: 305 Issue: 12 Pages: 911-918
- DOI
  10.1152/ajpgi.00225.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.2013
- Author(s)
  Zhang J, Nakatsu Y, Sinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  Ｊournal of Biological Chemistry
  
  Volume: 288 Issue: 28 Pages: 20692-20701
- DOI
  10.1074/jbc.m113.485730
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development.2013
- Author(s)
  Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 33 Issue: 8 Pages: 1986-1993
- DOI
  10.1161/atvbaha.113.301546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23591099, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PUBLICLY-25111705, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-25670762
[Journal Article] Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and atherosclerosis development2012
- Author(s)
  Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Issue: 2 Pages: 291-298
- DOI
  10.1161/atvbaha.111.234559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390238, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24790928
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.2012
- Author(s)
  Iwashita M, Sakoda H, Kushiyama A, Fujishiro M, Ohno H, Nakatsu Y, Fukushima T, Kumamoto S, Tsuchiya Y, Kikuchi T, Kurihara H, Akazawa H, Komuro I, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  American Journal of Physiology - Endocrinology and Metabolism
  
  Volume: 302 Issue: 3 Pages: 286-296
- DOI
  10.1152/ajpendo.00324.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23390213, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24790928
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuchi T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 53 Pages: 44526-44535
- DOI
  10.1074/jbc.m112.397133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24790928
[Journal Article] Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation : Potential link with metabolic complications2011
- Author(s)
  Nakarai, H, Yamashita, A, Nagayasu, S, Iwashita, M, Kumamoto, S, Ohyama, H, Hata, M, Soga, Y, Kushiyama, A, Asano, T, Abiko, Y, Nishimura, F
- Journal Title
  
  Innate Immunity
  
  Volume: 18 Issue: 1 Pages: 164-170
- DOI
  10.1177/1753425910393370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390497, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-23593076, KAKENHI-PROJECT-23791047
[Journal Article] Atrio-His (James) accessory pathway and infiltration of γδ T cells in the heart with MELAS2011
- Author(s)
  Matsuzaki G, Kushiyama A, Uto K, Shoda M, Seko Y
- Journal Title
  
  BMJ Case Rep
  
  Volume: 2011 Pages: bcr0920103359-bcr0920103359
- DOI
  10.1136/bcr.09.2010.3359
- Data Source
  KAKENHI-PROJECT-23791047
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis2011
- Author(s)
  Nakatsu Y, Sakoda H, Kushiyama A, Zhang J, Ono H, Fujishiro M, Kikuchi T, Fukushima T, Yoneda M, Ohno H, Horike N, Kanna M, Tsuchiya Y, Kamata H, Nishimura F, Isobe T, Ogihara T, Katagiri H, Oka Y, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 23 Pages: 20812-20822
- DOI
  10.1074/jbc.m110.206904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22248030, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity2011
- Author(s)
  Ohno H, Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Otani Y, Okubo H, Yoneda M, Fukushima T, Kamata H, Nishimura F, Kurihara H, Katagiri H, Oka Y, Asano T
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 300(5) Issue: 5 Pages: 1047-54
- DOI
  10.1152/ajpcell.00416.2010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047
[Journal Article] Risk of macrovascular disease stratified by stage of chronic kidney disease in type 2 diabetic patients: critical level of the estimated glomerular filtration rate and the significance of hyperuricemia2011
- Author(s)
  Tanaka K, Hara S, Kushiyama A, Ubara Y, Yoshida Y, Mizuiri S, Aikawa A, Kawatzu S
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15(3) Issue: 3 Pages: 391-7
- DOI
  10.1007/s10157-011-0420-6
- NAID
  10029005803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  櫛山暁史
- Journal Title
  
  Diabetes Research and Clinical Practice 87
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790756
[Journal Article] Regulation of gut-derived resistin-like molecule beta expression by nutrients2008
- Author(s)
  Fujio J, 櫛山暁史, 他
- Journal Title
  
  Diabetes Research and Clinical Practice 79
  
  Pages: 2-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Koketsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima Y, Ono H, Anai M, Kikuchi T, Fukuda T, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T
- Journal Title
  
  Am J Physiol Endocrinol Metab 294(4)
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptionaI activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.2008
- Author(s)
  Horike N, 櫛山暁史, 他
- Journal Title
  
  J Biol Chem 283
  
  Pages: 33902-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Regulation of gut-derived resistin-like molecule beta expression by nutrients.2008
- Author(s)
  Fujio J, Kushiyama A, Sakoda H, Fujishiro M, Ogihara T, Fukushima Y, Anai M, Horike N, Kamata H, Uchijima Y, Kurihara H, Asano T
- Journal Title
  
  Diabetes Res Clin Pract 79(1)
  
  Pages: 2-10
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Koketsu N, 櫛山暁史, 他
- Journal Title
  
  Am J Physiol Endocrinol Metab. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] AMP-activated protein kinase activation increases phosphorylation of glycogen synthase kinase 3beta and thereby reduces cAMP-responsive element transcriptional activity and phosphoenolpyruvate carboxykinase C gene expression in the liver.2008
- Author(s)
  Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T
- Journal Title
  
  J Biol Chem. 283(49)
  
  Pages: 33902-10
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells.2008
- Author(s)
  Egawa M, Kamata H, Kushiyama A, Sakoda H, Fujishiro M, Horike N, Yoneda M, Nakatsu Y, Ying G, Jun Z, Tsuchiya Y, Takata K, Kurihara H, Asano T
- Journal Title
  
  Placenta 29(12)
  
  Pages: 1003-8
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells.2008
- Author(s)
  Egawa M, 櫛山暁史, 他
- Journal Title
  
  Placenta 29
  
  Pages: 1003-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.2007
- Author(s)
  Ono H, Sakoda H, Fujishiro M, Anai M, Kushiyama A, Fukushima Y, Katagiri H, Ogihara T, Oka Y, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T
- Journal Title
  
  Am J Physiol Cell Physiol 293(5)
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Role of phosphatidylinositol 3-kinase activation on insulin action and its alteration in diabetic conditions.2007
- Author(s)
  Asano T, Fujishiro M, Kushiyama A, Nakatsu Y, Yoneda M, Kamata H, Sakoda H
- Journal Title
  
  Biol Pharm Bull 30(9)
  
  Pages: 1610-6
- NAID
  110006380237
- Data Source
  KAKENHI-PROJECT-19790644
[Journal Article] Physiological significance of resistin and resistin-like molecules in the inflammatory process and insulin resistance.2006
- Author(s)
  Asano T, Sakoda H, Fujishiro M, Anai M, Kushiyama A, Horike N, Kamata H, Ogihara T, Kurihara H, Uchijima Y
- Journal Title
  
  Curr Diabetes Rev. 2(4)
  
  Pages: 449-54
- Data Source
  KAKENHI-PROJECT-19790644
[Patent] ワクチン、医薬及び糖尿病合併症治療薬2021
- Inventor(s)
  櫛山暁史ほか
- Industrial Property Rights Holder
  櫛山暁史ほか
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-031201
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K11784
[Patent] ワクチン、医薬及び糖尿病合併症治療薬2021
- Inventor(s)
  長岡泰司、横田陽匡、山上聡、花栗潤哉、中神啓徳、林宏樹、櫛山暁史
- Industrial Property Rights Holder
  長岡泰司、横田陽匡、山上聡、花栗潤哉、中神啓徳、林宏樹、櫛山暁史
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-031201
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K11784
[Patent] 大腸癌、動脈硬化症又はメタボリックシンドロームの検出法2013
- Inventor(s)
  櫛山暁史
- Industrial Property Rights Holder
  櫛山暁史
- Industrial Property Rights Type
  特許
- Filing Date
  2013-02-28
- Data Source
  KAKENHI-PROJECT-23791047
[Patent] 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法2013
- Inventor(s)
  浅野知一郎、櫛山暁史
- Industrial Property Rights Holder
  広島大学・朝日生命成人病研究所
- Acquisition Date
  2013-03-29
- Data Source
  KAKENHI-PROJECT-23791047
[Patent] 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法2012
- Inventor(s)
  浅野知一郎、櫛山暁史
- Industrial Property Rights Holder
  広島大学・朝日生命成人病研究所
- Industrial Property Number
  2013-040964
- Filing Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-23791047
[Patent] 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法2007
- Inventor(s)
  櫛山暁史・浅野知一郎
- Industrial Property Rights Holder
  櫛山暁史・浅野知一郎
- Filing Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19790644
[Patent] 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法2007
- Inventor(s)
  櫛山暁史, 他1名
- Industrial Property Rights Holder
  櫛山暁史, 他1名
- Filing Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-21790756
[Patent] 大腸癌、動脈硬化症、又はメタボリックシンドロームの検出方法2007
- Inventor(s)
  浅野知一郎、櫛山暁史
- Industrial Property Rights Holder
  浅野知一郎、櫛山暁史
- Filing Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] 筋肉細胞のミトコンドリア形態変化と酸化ストレス及びアクチンの関与2023
- Author(s)
  馬場めぐみ、横山尚哉、高橋雅弘、山室大介、櫛山暁史
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 細胞における糖の違いによる炎症誘発効果の検討：2023
- Author(s)
  内田彩友美、高橋雅弘、冨田結惟、天池律樹、櫛山暁史
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 様々な血糖変動指標と2型糖尿病腎症発症進展の関連2023
- Author(s)
  藤坂紗彩、高橋雅弘、大塚美空、山之内美環、菊池貴子、櫛山暁史
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 糖尿病網膜症のバイオマーカーと代謝への介入2023
- Author(s)
  櫛山暁史
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 肥満糖尿病モデルマウスにおける運動療法の熱産生に対する効果2023
- Author(s)
  山口創大、高橋雅弘、鍵山菜菜子、畑山竣吏、天池律樹、冨田結惟、内田彩友美、櫛山暁史、
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 筋肉細胞におけるROS産生増加によるミトコンドリア形態変化への影響2023
- Author(s)
  馬塲めぐみ、横山尚哉、高橋雅弘、櫛山暁史
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] Analysis of trends in food and nutrition intake and eating habits of younger generation in modern Japan using quantification of the tendency toward the basic ”Washoku" pattern and "Japanese Dietary Pattern2023
- Author(s)
  Sakura Kushiyama, Minako Saito, Misaki Fuchigami, Eriko Yokoyama, Noriko Homma, Akifumi Kushiyama, Michiko Minami
- Organizer
  国際栄養学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] SGLT２阻害薬またはDPP4阻害薬開始後の肝線維化指標FIB-4 indexへの影響についての解析2023
- Author(s)
  菊池貴子、櫛山暁史
- Organizer
  第44回日本肥満学会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] J774.1マクロファージ様細胞における糖の違いによる代謝への影響2023
- Author(s)
  内田彩友美、高橋雅弘、冨田結惟、天池律樹、鍵山菜菜子、山口創大、畑山竣吏、野澤玲子、櫛山暁史
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 32.細胞質内Ca2＋濃度における小胞体ストレス応答のSGLT2の膜上発現量への影響2023
- Author(s)
  横山尚哉、櫛山暁史、高橋雅弘、馬塲めぐみ
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 高血糖・小胞体ストレス応答が与えるSGLT2発現・膜輸送への影響2023
- Author(s)
  横山尚哉、馬場めぐみ、山室大介、高橋雅弘、櫛山暁史
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] J774.1細胞における糖の違いによる炎症誘発効果の検討2023
- Author(s)
  内田彩友美、高橋雅弘、冨田結惟、天池律樹、櫛山暁史
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 細胞質内Ca2＋濃度における小胞体ストレス応答のSGLT2の膜上発現量への影響2023
- Author(s)
  横山尚哉、櫛山暁史、高橋雅弘、馬塲めぐみ
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-19K02314
[Presentation] 脂肪細胞のTrk-fused gene（TFG）はPPARγ発現量およびミトコンドリア機能を調節し，adipose expansionに重要である2021
- Author(s)
  山本屋武　長谷井竣　中津祐介　迫田秀之　藤城緑　櫛山暁史　浅野知一郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] エネルギーバランスへの介入とマクロファージの脂質受容体発現の関連2021
- Author(s)
  長沼彩佳、高橋雅弘、石橋瞳、吉川翔、福永珠未、池田舞花、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] データベースを用いた運動時の骨格筋における遺伝子発現解析2021
- Author(s)
  吉川翔、高橋雅弘、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 2型糖尿病患者における腱反射と腎機能低下の関連性の検討2021
- Author(s)
  村松泰地、高橋雅弘、柿沼怜奈、菊池貴子、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Luseogliflozinの治療におけるQOLの変化に関する検討（ルセフィQOL研究）第2報2021
- Author(s)
  櫛山暁史　朝長修　五十川陽洋　西村秀樹　長坂昌一郎　加藤光敏　折笠秀樹　岩本安彦
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 2型糖尿病を対象としたプリン体代謝関連物質の血管合併症発症および進展に対する影響の研究（続報）2021
- Author(s)
  藤城緑　櫛山暁史　小川克彦　渡邉健太郎　江頭富士子　岡本真由美　村瀬貴代　中村敬志　赤利精悟　迫田秀之　小野啓　山本屋武　中津祐介　浅野知一郎　石原寿光
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] プロリン異性化酵素Pin1は，ATGLの分解を促進することで脂肪分解活性を抑制する2021
- Author(s)
  中津祐介、山本屋武、青山俊也、長谷井竣、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第64回　日本糖尿病学会年次学術学会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] マウスマクロファージ様細胞J774.1におけるAICARによるエネルギーバランス変化に伴う泡沫化の抑制2021
- Author(s)
  石橋瞳、高橋雅弘、長沼彩佳、吉川翔、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] J774.1マクロファージのグルコース濃度による泡沫化調節機構2021
- Author(s)
  福永珠未、高橋雅弘、池田舞花、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] eGFR低下に対するCa拮抗薬の型とACEI/ARB併用の影響2021
- Author(s)
  中澤祐貴、高橋雅弘、東佳穂、水野亜美、菊池貴子、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] マクロファージ様細胞J774.1における基質となる糖の違いによるエネルギーバランスへの影響2021
- Author(s)
  内田彩友美1、高橋雅弘1、冨田結惟、天池律樹、福永珠未、野澤玲子、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] マクロファージ様細胞J774.1におけるタプシガルギンによる小胞体ストレスに伴う泡沫化への影響2021
- Author(s)
  冨田結惟、高橋雅弘、内田彩友美、天池律樹、福永珠未、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] ２型糖尿病患者のビグアナイド薬・DPP-4阻害薬・スルホニル尿素薬の使用と大腸がん発生リスクの関連2021
- Author(s)
  水野亜美、高橋雅弘、東佳穂、中澤祐貴、菊池貴子、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 代謝に依存した生活習慣病における血管障害2021
- Author(s)
  櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 2型糖尿病におけるDiabetic kidney disease(DKD)の進展と既往最大BMIの関連の検討2021
- Author(s)
  東佳穂、高橋雅弘、水野亜美、中澤祐貴、菊池貴子、櫛山暁史
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] ローズマリー抽出物carnosic acid, carnosolによる培養肝細胞のAMPK活性化及び代謝と細胞増殖抑制への作用2021
- Author(s)
  長谷井竣、山本屋武、中津祐介、大畠侑乃、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第64回　日本糖尿病学会年次学術学会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Trk-fused gene（TFG）の脂肪細胞における代謝制御機構の解明2021
- Author(s)
  山本屋武、長谷井竣、中津祐介、大畠侑乃、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第64回　日本糖尿病学会年次学術学会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] プロリン異性化酵素Pin1を介した肝星細胞の活性化制御機構の解明2021
- Author(s)
  青山峻也、中津祐介、山本屋武、長谷井竣、迫田秀之、藤城緑、櫛山暁史、浅野知一郎
- Organizer
  第64回　日本糖尿病学会年次学術学会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 非LDLの血管障害リスク～血糖・尿酸など～2019
- Author(s)
  櫛山　暁史
- Organizer
  第27回血管生物医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 都市部における2型糖尿病患者の初診時臨床像の変遷2019
- Author(s)
  吉田洋子、櫛山暁史、髙尾淑子、大西由希子、田原たづ、菊池貴子、高橋和之、震明あすか、春日雅人
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Relationship between plaque destabilization and glucose / nucleic acid metabolism.2019
- Author(s)
  Kushiyama A, Takahashi M, Nakagami H
- Organizer
  Inaugural Joint Scientific Meeting of AVBS/ANZMS/AAVBM
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] SGLT2阻害薬によるマウス糖尿病性腎障害の改善及び，腎Pin1発現量の是正とAMPK活性化の関与2019
- Author(s)
  井上賢紀、中津祐介、松永泰花、山本屋武、上田晃嗣、井上由貴、水野優、櫛山暁史、浅野知一郎
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] キサンチンオキシダーゼ阻害薬febuxostatによる糖尿病性腎症の改善とその機序の解明2019
- Author(s)
  水野優、中津祐介、山本屋武、上田晃嗣、井上賢紀、藤城緑、迫田秀之、櫛山暁史、浅野知一郎
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 2型糖尿病を対象としたプリン体代謝関連物質の血管合併症発症および進展に対する影響の研究2019
- Author(s)
  藤城緑、櫛山暁史、小川克彦、山口賢、渡邉健太郎、村瀬貴代、中村敬志、赤利精悟、山本屋武、中津祐介、浅野知一郎、石原寿光
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 糖尿病の病態における尿酸代謝の役割2019
- Author(s)
  櫛山暁史
- Organizer
  第52回日本痛風・核酸代謝学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 肥満症の成人に対する短期間の厳密な低糖質食（糖質50gまたは120g）介入による前向き研究結果2019
- Author(s)
  菊池貴子、櫛山暁史、春日雅人
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Novel therapeutics for diabetic retinopathy:2019
- Author(s)
  Kushiyama A
- Organizer
  Symposium on Interdisciplinary Approach for the Development of Novel Diagnosis and Treatment of Retinal Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Pin1 and Trk-fused gene（TFG）：novel regulators for β-cell mass and function2019
- Author(s)
  山本屋武、中津祐介、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第62回糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] 尿酸と尿酸産生の血管疾患マーカーとしての役割2019
- Author(s)
  櫛山暁史
- Organizer
  第83回日本循環器学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Luseogliflozinの治療におけるQOLの変化に関する検討（ルセフィQOL研究）2019
- Author(s)
  櫛山暁史、朝長修、五十川陽洋、西村秀樹、長坂昌一郎、加藤光敏、折笠秀樹、岩本安彦
- Organizer
  第62回糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K11784
[Presentation] Role of xanthine oxidoreductase from mesenchymal cells in retinal inflammation after pericyte breakdown2018
- Author(s)
  AKIFUMI KUSHIYAMA, TAKAKO KIKUCHI, HIROKI YAMAZAKI, TAKESHI YAMAMOTOYA, HIDEYUKI SAKODA, MIDORI FUJISHIRO, YUSUKE NAKATSU, AKIYOSHI UEMURA, TAKASHI SHIRAKURA, TOMOICHIRO ASANO, YASUHIKO IWAMOTO
- Organizer
  ADA　American Diabetes Association　78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] マクロファージ由来キサンチン酸化還元酵素の代謝・熱産生への関与2018
- Author(s)
  櫛山暁史, 菊池貴子, 藤城緑, 迫田秀之, 中村敬志, 村瀬貴代, 松永泰花, 山本屋武, 中津祐介, 浅野知一郎, 岩本安彦
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Xanthine Oxidoreductaseの組織特異的発現による代謝制御2018
- Author(s)
  櫛山暁史、菊池貴子、村瀬貴代、世良康如、藤城緑、山本屋武、中津祐介、中村敬志、本田浩章、春日雅人、浅野知一郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] ペリサイト障害モデルにおける血管透過性に対するキサンチンオキシダーゼの役割2018
- Author(s)
  櫛山暁史、菊池貴子、植村明嘉、福嶋葉子、櫛山櫻、浅野知一郎
- Organizer
  日本血管生物医学会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] ビグアナイド系薬剤服用患者のアドヒアランスに関する要因2018
- Author(s)
  谷口洸亮、櫛山暁史、末永みどり、庄野あい子、菊池貴子、岩本安彦、赤沢学
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Role of uric acid metabolism in pathogenesis of diabetes mellitus2018
- Author(s)
  AKIFUMI KUSHIYAMA
- Organizer
  3rd EAGER Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 妊娠中毒症を伴う妊娠および出産と 2 型糖尿病発症の関連2018
- Author(s)
  末永みどり, 櫛山暁史, 庄野あい子, 赤沢学
- Organizer
  日本薬学会　第138年会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 2型糖尿病を対象としたキサンチン酸化還元酵素の血管合併症発症および進展に対する影響に関する探索研究2018
- Author(s)
  藤城　緑、櫛山　暁史、山口　賢、渡邉　健太郎、江頭　富士子、岡本　真由美、村瀬　貴代、中村　敬志、山本屋　武、中津　祐介、浅野　知一郎、石原　寿光
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 糖尿病専門医による 2 型糖尿病患者の処方変更の実態2017
- Author(s)
  仙石悠紀子, 米川拓渡, 櫛山暁史, 山崎広貴, 菊池貴子, 庄野あい子, 金井紀仁, 赤沢学
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Inhibition of diabetic retinopathy by xanthine oxidase inhibitor2017
- Author(s)
  櫛山　暁史, 菊池貴子, 植村明嘉, 福嶋葉子,櫛山櫻, 岩本安彦, 浅野知一郎
- Organizer
  Molecular Cardiovascular Metabolic Conference
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 安全かつ効果的に結果にコミットできる減量方法の確立を目指して2017
- Author(s)
  櫛山暁史
- Organizer
  第38回日本肥満学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] ペリサイト障害モデルにおける網膜浮腫に対するキサンチンオキシダーゼ阻害の効果2017
- Author(s)
  櫛山　暁史, 菊池貴子, 植村明嘉, 福嶋葉子,櫛山櫻, 岩本安彦, 浅野知一郎
- Organizer
  第25回日本血管生物医学会学術集会(CVMW2017)
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Molecular mechanism of retinal edema by xanthine oxidase inhibitor2017
- Author(s)
  櫛山　暁史, 菊池貴子, 植村明嘉, 福嶋葉子,櫛山櫻, 岩本安彦, 浅野知一郎
- Organizer
  2017年度生命科学系学会合同年次大会（ConBIo2017）
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 糖尿病専門医院における患者背景のデータベース構築2017
- Author(s)
  米川拓渡, 沖村悠希, 梶山里奈, 小泉聖人,仙石悠紀子,宮下紗季,森田修司,金井紀仁,櫛山暁史,山崎広貴,菊池貴子, 赤沢学
- Organizer
  日本薬学会第137年会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 組織特異的キサンチンオキシダーゼによるインスリン感受性と慢性炎症の制御2017
- Author(s)
  櫛山　暁史, 菊池貴子, 植村明嘉, 福嶋葉子,櫛山櫻, 岩本安彦, 浅野知一郎
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Inhibition of endothelial sprouting by the xanthine oxidase inhibitor2016
- Author(s)
  Akifumi Kushiyama, Takako Kikuchi, Hiroki Yamazaki, Sakura Kushiyama, Yasuhiko Iwamoto, Tomoichiro Asano
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール(長崎)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 2型糖尿病患者男女における骨密度及び海綿骨スコアの変化2016
- Author(s)
  櫛山暁史、山崎広貴、藤田政子、菊池貴子、田原たづ、大西由希子、高尾淑子、吉田洋子、岩本安彦、板橋明
- Organizer
  第18回　骨粗しょう症学会
- Place of Presentation
  仙台　勝山館（宮城）
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] Anti-angiogenic effect of xanthine oxidase inhibition on endothelial cells2016
- Author(s)
  Akifumi Kushiyama, Takako Kikuchi, Hiroki Yamazaki, Yoko Fukushima, Akiyoshi Uemura, Yuichiro Arima, Koichi Nishiyama, Sakura Kushiyama, Yasuhiko Iwamoto, Tomoichiro Asano
- Organizer
  IVBM2016
- Place of Presentation
  Sheraton Boston Hotel (USA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 組織特異的キサンチン酸化還元酵素のインスリン抵抗性に果たす役割2016
- Author(s)
  櫛山暁史、菊池貴子、山崎広貴、藤田政子、嶋崎喜代子、櫛山櫻、浅野知一郎、西山功一、有馬勇一郎、栗原裕基
- Organizer
  MCCII
- Place of Presentation
  東京ドームホテル（東京）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 医療機関での取り組み－初診時療養指導と受診中断者への働きがけによる受診中断対策2016
- Author(s)
  吉田洋子　櫛山暁史　岩本安彦
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 血管新生におけるキサンチンオキシダーゼ阻害の血管内皮細胞への影響 Effect of xanthine oxidase inhibitor on endothelial cells during angiogenesis2016
- Author(s)
  櫛山暁史、菊池貴子、山崎広貴、福嶋葉子、植村明嘉、西山功一、有馬勇一郎、櫛山櫻、岩本安彦、浅野知一郎
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 糖尿病患者に対するMCG解析2016
- Author(s)
  櫛山暁史
- Organizer
  第57回　日本人間ドック学会学術大会
- Place of Presentation
  まつもと市民芸術館(長野)
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] 肝外キサンチンオキシダーゼのインスリン抵抗性への関与2016
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、岩本安彦、浅野知一郎
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-16K09791
[Presentation] フルクトースの誘導する炎症におけるマクロファージ由来キサンチン酸化還元酵素の役割2015
- Author(s)
  櫛山暁史
- Organizer
  第6回Molecular Cardiovascular Conference II
- Place of Presentation
  兵庫県
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、岩本安彦、浅野知一郎
- Organizer
  第58回日本糖尿病学会学術集会
- Place of Presentation
  山口県
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 尿酸代謝と粥状動脈硬化・高すぎる尿酸値と低すぎる尿酸値の動脈硬化リスク2015
- Author(s)
  櫛山暁史
- Organizer
  第47回　動脈硬化学会学術集会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Novel insights into anti-diabetic effects of sex hormone binding globulin (SHBG): anti-inflammatory actions on both adipocytes and macrophages2015
- Author(s)
  H Yamazaki, A Kushiyama, H Sakoda, M Fujishiro, T Asano
- Organizer
  Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  京都府
- Year and Date
  2015-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Extrahepatic xanthine oxidoreductase as a therapeutic target for diabetes mellitus and its complications2015
- Author(s)
  A Kushiyama, T Kikuchi, H Yamazaki, H Sakoda, Y Iwamoto, T Asano
- Organizer
  Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  京都府
- Year and Date
  2015-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Multifunctional Cardiography（MCG）を用いた2型糖尿病患者の心筋虚血の検出2013
- Author(s)
  常田智子，福井美弥子，新井恵，難波敏子，宮城よう子，吉川美帆，山本美津代，板橋明，田原たづ，吉田洋子，河津捷二，櫛山暁史
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本県
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Involvement of macrophage-derived　resistin like molecule β in atherosclerosis development2013
- Author(s)
  A. Kushiyama, T. Kikuchi, H. Sakoda, M. Fujishiro, K. Nishiyama, H. Kurihara, Y. Higashi, S. Kawazu, T. Asano
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 空腹時活性化GLP-1によるDPP4阻害薬シタグリプチンの効果予測2013
- Author(s)
  櫛山暁史，菊池貴子，大西由希子，田原たづ，髙尾淑子，山本万友美，須澤直木，吉田洋子，河津捷二
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本県
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 食事成分が誘引となる血管障害2013
- Author(s)
  櫛山暁史，菊池貴子，櫛山櫻，浅野知一郎，西山功一，栗原裕基
- Organizer
  第4回 Molecular Cardiovascular Conference II
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] インスリン抵抗性および大血管障害におけるマクロファージ由来resistin like molecule βの意義2012
- Author(s)
  櫛山暁史
- Organizer
  第24回分子糖尿病学シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] A 20-year trend of patients with type 2 diabetes at first diagnosis in urban Japan2012
- Author(s)
  櫛山暁史
- Organizer
  2012 IDF-WPR AASD
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] インスリン分泌能と関連する血糖変動指標の特徴2012
- Author(s)
  櫛山暁史
- Organizer
  第55回日本糖尿病学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] Mechanism of atherosclerosis development facilitated by resistin like molecule beta2011
- Author(s)
  櫛山　暁史
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  神戸ポートピアホテル(兵庫県　神戸市)
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] ２型糖尿病患者における骨折リスクに関する横断的研究2011
- Author(s)
  櫛山　暁史
- Organizer
  第１３回骨粗鬆症学会　健診・骨ドック分科会
- Place of Presentation
  神戸国際会議場（兵庫県　神戸市）
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] キサンチンオキシダーゼ経路のマクロファージ泡沫化と動脈硬化への関与（一般口演）2011
- Author(s)
  櫛山　暁史
- Organizer
  第５４回日本糖尿病学会学術総会
- Place of Presentation
  札幌プリンスホテル（北海道　札幌市）
- Data Source
  KAKENHI-PROJECT-23791047
[Presentation] マクロファージから分泌されるレジスチン様分子β(RELMβ)の生理的意義とインスリン抵抗性の発症機序2010
- Author(s)
  櫛山暁史, 迫田秀之, 菊池貴子, 大西由希子, 佃克則, 藤城緑, 纐纈優子, 櫛山櫻, 佐藤博和, 菊池方利, 大野晴也, 大久保博史, 張君, 郭瑩, 中津祐介, 河津捷二, 浅野知一郎
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] マクロファージから分泌されるレジスチン様分子β(RELMβ)の生理的意義とインスリン抵抗性の発症機序2010
- Author(s)
  櫛山暁史, 迫田秀之, 菊池貴子, 大西由希子, 佃克則, 藤城緑, 纐纈優子, 櫛山櫻, 佐藤博和, 菊池方利, 大野晴也, 大久保博史, 張君, 郭瑩, 中津祐介, 河津捷二, 浅野知一郎
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] インスリン抵抗性を誘導するレジスチンファミリー分子(resistin, RELMβ)の動脈硬化への独立した役割の解析2009
- Author(s)
  櫛山暁史, 迫田秀之, 藤城緑, 纐纈優子, 菊池貴子, 大西由希子, 佃克則, 佐藤博和, A.Viana, 高城直幸, 飯塚正樹, 櫛山櫻, 油谷浩幸, 栗原裕基, 菊池方利, 浅野知一郎
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪府
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] 腸管およびマクロファージに由来するレジスチン様分子βは動脈硬化・インスリン抵抗性の進展及び発がんに関与する2009
- Author(s)
  櫛山暁史
- Organizer
  分子生物学会2009
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] 腸管およびマクロファージに由来するレジスチン様分子βは動脈硬化・インスリン抵抗性の進展及び発がんに関与する2009
- Author(s)
  櫛山暁史, 菊池貴子, 大西由希子, 佃克則, 河津捷二, 佐藤博和, 迫田秀之, 藤城緑, 纐纈優子, 仙谷和弘, 大上直秀, 石垣泰, 片桐秀樹, 浅野知一郎
- Organizer
  分子生物学会
- Place of Presentation
  神奈川県
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] インスリン抵抗性を誘導するレジスチンファミリー分子(resistin、RELMβ)の動脈硬化への独立した役割の解析2009
- Author(s)
  櫛山暁史
- Organizer
  第52回日本糖尿病学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21790756
[Presentation] Functionally distinct roles of each member of the resistin family in insulin resistance and atherosclerosis2008
- Author(s)
  櫛山暁史, 他
- Organizer
  68^<th> ADA scientific session
- Place of Presentation
  San Francisco, USA
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] インスリン抵抗性を誘導するレジスチンファミリー(resistin/RELMβ)は各々異なった機序で動脈硬化に関与する2008
- Author(s)
  櫛山暁史, 浅野知一郎, 迫田秀之, 藤城緑, 纐纈優子, 福田武俊, 佃克則, 大西由希子, Amelia, 犬飼浩一, 菊池方利
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] インスリン抵抗性を誘導するレジスチンファミリー(resistin/RELMβ)は各々異なった機序で動脈硬化に関与する2008
- Author(s)
  櫛山暁史, 他
- Organizer
  第51回日本糖尿病学会学術総会
- Place of Presentation
  Tokyo
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] Functionally distinct roles of each member of the resistin family in insulin resistance and atherosclerosis2008
- Author(s)
  A. Kushiyama, H. Sakoda, M. Fujishiro, H. Ohno, M. Yoneda, Y. Nakatsu, H. Kamata, M. Kikuchi, T. Asano
- Organizer
  68th American Diabetes Association Scientific Sessions
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] Resistin-like molecule(RELM)βは内皮機能障害及び炎症反応を介して動脈硬化に関与する2007
- Author(s)
  櫛山暁史, 浅野知一郎, 迫田秀之, 藤城緑, 纐纈優子, 穴井元暢, 油谷浩幸, 栗原裕基, 菊池方利
- Organizer
  BMB2007
- Place of Presentation
  神奈川県
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] 腸管由来RELM(resistin like molecules)βは動脈硬化・メタボリック症候群に関与する2007
- Author(s)
  櫛山暁史, 他
- Organizer
  第50回日本糖尿病学会学術総会
- Place of Presentation
  Sendai
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] Resistin like molecule beta induces atherosclerosis via directly impairing vascular endothelial function and priming inflammation as a mediator of immune-response2007
- Author(s)
  櫛山暁史, 他
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] Increased RELMβ expression in saturated fatty acid-treated colonic cells: possible involvement of toll-like receptors2007
- Author(s)
  A. Y. I VIANA, 櫛山暁史, 他
- Organizer
  13th international congress of immunology
- Place of Presentation
  Rio de Janeiro
- Year and Date
  2007-08-21
- Data Source
  KAKENHI-PROJECT-19790644
[Presentation] Involvement of Resistin-like molecule β in the development of non-alcoholic steatohepatitis
- Author(s)
  Akifumi Kushiyama, Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Toshiaki Fukushima, Shin-ichiro Takahashi, Tomoichiro Asano
- Organizer
  第74回米国糖尿病学会議
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] マクロファージresistin like moleculeβによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 食事成分に起因する組織特異的キサンチン酸化還元酵素を介した核酸代謝と酸化ストレス
- Author(s)
  櫛山暁史、菊池貴子、藤田政子、櫛山櫻、浅野知一郎、西山功一、栗原裕基
- Organizer
  第5回MCC（Molecular Cardiovascular Conference） II
- Place of Presentation
  大阪
- Year and Date
  2014-09-04 – 2014-09-05
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] resistin like moleculeβを介したマクロファージ分化と炎症
- Author(s)
  櫛山暁史　菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Macrophage resistin-like molecule β is involved in atherosclerosis development.
- Author(s)
  Akifumi Kushiyama, Takako Kikuchi, Hideyuki Sakoda, Koichi Nishiyama, Hiroki Kurihara, Tomoichiro Asano, Shoji Kawazu
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 糖代謝に伴う核酸代謝由来酸化ストレスと臓器障害
- Author(s)
  櫛山暁史、櫛山櫻、菊池貴子、栗原裕基、浅野知一郎、河津捷二
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25461372

1. ASANO Tomoichiro (70242063)

# of Collaborated Projects: 3 results

# of Collaborated Products: 37 results
2. SAKODA Hideyuki (50376464)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
3. KURIHARA Hiroki (20221947)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
4. 長岡泰司 (00333691)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 横田陽匡 (60431417)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 長井紀章 (90411579)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Minami Michiko (70272432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 岩下未咲 (80611326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西村英紀 (80208222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 木村航 (60452182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 川辺淳一 (10400087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHIZUMI Masao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NAKATSU Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
14. ONO Hiraku

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
15. YAMASHITA Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 石丸直澄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 安孫子宜光

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 山本屋武

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
19. 小久保博樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 鎌田英明

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
22. 福嶋俊明

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
23. 松原昭郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 栗原由紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 片桐秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 石原寿光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 早河翼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kushiyama Akifumi 櫛山 暁史

KUSHIYAMA Akifumi 櫛山 曉史

櫛山 曉史 クシヤマ アキフミ

Research Projects

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Co-Researchers

The role of inflammatory Cell Death (Pyroptosis) in the Pathogenesis of Diabetic Retinopathy and Novel Nanoparticle Eye Drop Therapy

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Overcoming Diabetic Retinopathy through Local Control of Oxidative StressPrincipal Investigator

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歯周病と動脈硬化―微細炎症合併日本人型軽度肥満モデルでの検討

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Potentiality of dietary fiber for healthy longevity

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The essence of health disorder caused by purine bodies as the substratesPrincipal Investigator

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Related elucidation of the tissue-specific pudding metabolism state and lifestyle-related diseasePrincipal Investigator

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Elucidation of pathogenesis of the onset of lifestyle-related diseases due to oxidative stress derived from diet componentsPrincipal Investigator

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The role of resistin-like molecules in natural immune system involving insulin resistance.Principal Investigator

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Investigation for the effects of macrophage-derived resistin like molecule on development of atherosclerosisPrincipal Investigator

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Investigation of roles of resistin like molecule beta in pathogenesis of atherosclerosisPrincipal Investigator

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[Book] 最新基礎栄養学2019

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[Book] 糖尿病の療養指導Q＆A vol.22019

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[Book] 『ここまで明らかになった！尿酸代謝ワールドと高尿酸血症の病態解明～診療と医学の最前線～』(動脈硬化（尿酸と血管リモデリング）の形成と進展 アテローム性動脈硬化)2015

Author(s)

Kushiyama Akifumi 櫛山暁史

KUSHIYAMA Akifumi 櫛山曉史

櫛山曉史クシヤマアキフミ

[Book] 『ここまで明らかになった！尿酸代謝ワールドと高尿酸血症の病態解明～診療と医学の最前線～』(動脈硬化（尿酸と血管リモデリング）の形成と進展　アテローム性動脈硬化)2015

[Journal Article] シームレスな「人体の構造と機能」の学習を実現するための医療系大学入学前後の学習項目の調査2023