UENO NOBUHIRO 上野伸展

… Alternative Names

UENO Nobuhiro 上野伸展

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Researcher Number	30436000
Other IDs	https://orcid.org/0000-0001-5448-4766
Affiliation (Current)	2026: 旭川医科大学, 医学部, 特任講師
Affiliation (based on the past Project Information) *help	2017 – 2025: 旭川医科大学, 医学部, 特任講師 2011 – 2016: 旭川医科大学, 医学部, 助教 2010: 旭川医科大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Basic Section 55060:Emergency medicine-related / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 腸内細菌 / ポリリン酸 / 腸内細菌叢 / 過敏性腸症候群 / プロバイオティクス Except Principal Investigator プロバイオティクス / 腸内細菌 / 腸内細菌叢 / 炎症性腸疾患 / ポリリン酸 … More / 消化器癌 / 抗菌ペプチド / 腸管免疫 / 皮膚腸管連関 / 腸－肺連関 / ARDS / 腸ー肺連関 / Dysbiosis / 腸管バリア / 多臓器不全 / 重症急性膵炎 / 急性膵炎 / 敗血症 / 腸管保護 / 抗腫瘍 / ビフィズス菌 / 乳酸菌 / 麹菌 / 大腸腫瘍 / Heptelidic acid / フェリクローム / 認識機構 / 口腔内細菌 / バレット食道 / 食道癌 / 大腸癌 / 腸炎 / トランスポーター / バイオフィルム Less

Reg3を介した皮膚腸管連関の制御機構解明
- Principal Investigator
  
  堂腰達矢
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
A research on ARDS treatment based on the mechanism of gut-lung axis by molecules derived from probiotics
- Principal Investigator
  
  Takauji Shuhei
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Hokkaido University
  Asahikawa Medical College
Identifications and functional analyses of beneficial bacteria-derived bioactive molecules
- Principal Investigator
  
  Fujiya Mikihiro
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Novel therapy for sepsis with probiotic-derived intestinal barriers enhancing molecules
- Principal Investigator
  
  Takauji Shuhei
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Asahikawa Medical College
Development of novel preventive and therapeutic substance derived from oral flora or probiotics
- Principal Investigator
  
  Moriichi Kentaro
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
An analysis of the mechanisms through which bacteria-derived bioactive molecules protect the intestine in enteritis models and primary cultured cells
- Principal Investigator
  
  Fujiya Mikihiro
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
The alteration of microbiota and the efficiency of treatment for IBS model mice by the novel probiotics, Lactobacillus brevis SB88Principal Investigator
- Principal Investigator
  
  Ueno Nobuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Cytoprotective effects of bioactive molecules derived from bacteria in the intestinal biofilm
- Principal Investigator
  
  KOHGO Yutaka
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College

All 2021 2020 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

[Journal Article] Polyphosphate, derived from the probiotic Lactobacillus brevis, modulates the intestinal microbiome and attenuates acute pancreatitis.2021
- Author(s)
  Takauji S, Konishi H, Fujiya M, Ueno N, Tanaka H, Sato H, Isozaki S, Kashima S, Moriichi K, Mizukami Y, Okumura T.
- Journal Title
  
  Dig Dis Sci
  
  Volume: - Issue: 11 Pages: 1-1
- DOI
  10.1007/s10620-020-06747-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-18K08906, KAKENHI-PROJECT-20H03655
[Journal Article] Bacteria-derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis-associated cancer.2021
- Author(s)
  Iwama T, Fujiya M, Konishi H, Tanaka H, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T.
- Journal Title
  
  Cancer Cell Int
  
  Volume: 21 Issue: 1 Pages: 21-21
- DOI
  10.1186/s12935-020-01723-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K17419
[Journal Article] Probiotic Aspergillus oryzae produces anti-tumor mediator and exerts anti-tumor effects in pancreatic cancer through the p38 MAPK signaling pathway.2021
- Author(s)
  Konishi H, Isozaki S, Kashima S, Moriichi K, Ichikawa S, Yamamoto K, Yamamura C, Ando K, Ueno N, Akutsu H, Ogawa N, Fujiya M.
- Journal Title
  
  Sci Rep
  
  Volume: 11 Issue: 1 Pages: 11070-11070
- DOI
  10.1038/s41598-021-90707-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19H03345, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17419
[Journal Article] Probiotic derived polyphosphate accelerates intestinal epithelia wound healing through inducing platelet-derived mediators.2021
- Author(s)
  Isozaki S, Konishi H, Fujiya M, Tanaka H, Murakami Y, Kashima S, Ando K, Ueno N, Moriichi K, Okumura T.
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2021:5582943 Issue: 1 Pages: 1-14
- DOI
  10.1155/2021/5582943
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K17419
[Journal Article] Probiotic-derived ferrichrome inhibits the growth of refractory pancreatic cancer cells.2020
- Author(s)
  Kita A, Fujiya M, Konishi H, Tanaka H, Kashima S, Iwama T, Ijiri M, Murakami Y, Takauji S, Goto T, Sakatani A, Ando K, Ueno N, Ogawa N, Okumura T.
- Journal Title
  
  Int J Oncol
  
  Volume: 57 Issue: 3 Pages: 721-732
- DOI
  10.3892/ijo.2020.5096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17419, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-18K15770
[Journal Article] A Case of Alpha-Fetoprotein-Producing Adenocarcinoma of the Esophagogastric Junction in which Long-Term Survival Was Achieved by Means of Individualized Multidisciplinary Therapy2018
- Author(s)
  Tanaka Kazuyuki、Fujiya Mikihiro、Ijiri Masami、Takahashi Keitaro、Ando Katsuyoshi、Nomura Yoshiki、Ueno Nobuhiro、Kashima Shin、Goto Takuma、Sasajima Junpei、Ito Takahiro、Moriichi Kentaro、Mizukami Yusuke、Tanabe Hiroki、Okumura Toshikatsu
- Journal Title
  
  Journal of Gastrointestinal Cancer
  
  Volume: - Issue: 3 Pages: 617-620
- DOI
  10.1007/s12029-018-0078-3
- NAID
  120006496820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15911, KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-17K09472
[Journal Article] An elevated expression of serum exosomal microRNA-191, -21, -451a of pancreatic neoplasm is considered to be efficient diagnostic marker2018
- Author(s)
  Goto Takuma、Fujiya Mikihiro、Konishi Hiroaki、Sasajima Junpei、Fujibayashi Shugo、Hayashi Akihiro、Utsumi Tatsuya、Sato Hiroki、Iwama Takuya、Ijiri Masami、Sakatani Aki、Tanaka Kazuyuki、Nomura Yoshiki、Ueno Nobuhiro、Kashima Shin、Moriichi Kentaro、Mizukami Yusuke、Kohgo Yutaka、Okumura Toshikatsu
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 1-11
- DOI
  10.1186/s12885-018-4006-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-17K15912, KAKENHI-PROJECT-17K15913, KAKENHI-PROJECT-16H06607, KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-15K19306
[Journal Article] Ferrichrome identified from Lactobacillus casei ATCC334 induces apoptosis through its iron-binding site in gastric cancer cells2017
- Author(s)
  Ijiri Masami、Fujiya Mikihiro、Konishi Hiroaki、Tanaka Hiroki、Ueno Nobuhiro、Kashima Shin、Moriichi Kentaro、Sasajima Junpei、Ikuta Katsuya、Okumura Toshikatsu
- Journal Title
  
  Tumor Biology
  
  Volume: 39 Issue: 6 Pages: 101042831771131-101042831771131
- DOI
  10.1177/1010428317711311
- NAID
  120006473651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06607, KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-15K19306
[Journal Article] 上部消化管内視鏡を用いたクローン病診断における「竹の節状外観」の臨床的意義2016
- Author(s)
  田邊裕貴, 横田欽一, 野村好紀, 安藤勝祥, 坂谷慧, 田中一之, 堂腰達矢, 嘉島伸, 上野伸展, 稲場勇平, 伊藤貴博, 須藤大輔, 太田勝久, 一石英一郎, 佐藤貴一, 大竹孝明, 高後裕, 盛一健太郎, 藤谷幹浩．
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 113 Pages: 1208-1215
- NAID
  130005162983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460956
[Journal Article] Soluble bioactive microbial mediators regulate proteasomal degradation and autophagy to protect against inflammation-induced stress.2016
- Author(s)
  Inaba Y, Ueno N, Numata M, Zhu X, Messer JS, Boone DL, Fujiya M, Kohgo Y, Musch MW, Chang EB.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 311 Issue: 4 Pages: G634-G647
- DOI
  10.1152/ajpgi.00092.2016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956
[Journal Article] Probiotic-derived ferrichrome inhibits colon cancer progression via JNK-mediated apoptosis2016
- Author(s)
  Hiroaki Konishi, Mikihiro Fujiya, Hiroki Tanaka, Nobuhiro Ueno, Kentaro Moriichi, Junpei Sasajima, Katsuya Ikuta, Hiroaki Akutsu, Hiroki Tanabe, Yutaka Kohgo
- Journal Title
  
  Nature Communications
  
  Volume: 7:12365 Issue: 1 Pages: 12365-12365
- DOI
  10.1038/ncomms12365
- NAID
  120006305684
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06607, KAKENHI-PROJECT-15K09446, KAKENHI-PROJECT-26460956
[Journal Article] A meta-analysis of efficacy and adverse events of cold vs. hot polypectomy.2016
- Author(s)
  Fujiya M, Sato H, Ueno N, Sakatani A, Tanaka K, Dokoshi T, Fujibayashi S, Nomura Y, Kashima S, Gotoh T, Sasajima J, Moriichi K, Watari J, Kohgo Y.
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 21 Issue: 23 Pages: 5436-44
- DOI
  10.3748/wjg.v22.i23.5436
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-15K19306
[Journal Article] Lactobacillus brevis-derived polyphosphate inhibits colon cancer progression through the induction of cell apoptosis.2016
- Author(s)
  Sakatani A, Fujiya M, Ueno N, Kashima S, Sasajima J, Moriichi K, Ikuta K, Tanabe H, Kohgo Y.
- Journal Title
  
  Anticancer Res
  
  Volume: 36 Pages: 591-598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460956
[Journal Article] Polyphosphate, an active molecule derived from probiotic Lactobacillus brevis, improves the fibrosis in murine colitis.2015
- Author(s)
  Kashima S, Fujiya M, Konishi H, Ueno N, Inaba Y, Moriichi K, Tanabe H, Ikuta K, Ohtake T, Kohgo Y.
- Journal Title
  
  Transl Res.
  
  Volume: in press Issue: 2 Pages: 00069-9
- DOI
  10.1016/j.trsl.2015.02.002
- NAID
  120005837997
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460923, KAKENHI-PROJECT-25860516, KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-25460969, KAKENHI-PROJECT-26860490
[Journal Article] Heterogeneous nuclear ribonucleoprotein A1 improves the intestinal injury by regulating apoptosis via trefoil factor 2 in mice with anti-CD3-induced enteritis.2015
- Author(s)
  Ando K, Fujiya M, Konishi H, Ueno N, Inaba Y, Moriichi K, Ikuta K, Tanabe H, Ohtake T, Kohgo Y.
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 21 Issue: 7 Pages: 1541-1552
- DOI
  10.1097/mib.0000000000000401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-25460969
[Journal Article] Efficacy and adverse events of EMR and endoscopic submucosal dissection for the treatment of colon neoplasms: a meta-analysis of studies comparing EMR and endoscopic submucosal dissection.2015
- Author(s)
  Fujiya M, Tanaka K, Dokoshi T, Tominaga M, Ueno N, Inaba Y, Ito T, Moriichi K, Kohgo Y.
- Journal Title
  
  Gastrointest Endosc.
  
  Volume: 81 Issue: 3 Pages: 583-95
- DOI
  10.1016/j.gie.2014.07.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460923, KAKENHI-PROJECT-26460956
[Journal Article] Probiotic-derived polyphosphate improves the intestinal barrier function through the caveolin-dependent endocytic pathway.2015
- Author(s)
  Tanaka K, Fujiya M, Konishi H, Ueno N, Sasajima J, Moriichi K, Ikuta K, Tanabe H, Kohgo Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 467 Issue: 3 Pages: 541-548
- DOI
  10.1016/j.bbrc.2015.09.159
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956, KAKENHI-PROJECT-15K19306, KAKENHI-PROJECT-15K19307, KAKENHI-PROJECT-26860490
[Journal Article] Decreased vessel networks and irregular vessel on narrow band imaging are useful findings to distinguish intestinal lymphoma from lymphoid hyperplasia.2014
- Author(s)
  Fujiya M, Kashima S, Ikuta K, Dokoshi T, Sakatani A, Tanaka K, Ando K, Ueno N, Tominaga M, Inaba Y, Ito T, Moriichi K, Tanabe H, Saitoh Y, Kohgo Y.
- Journal Title
  
  Gastrointestinal Endoscopy
  
  Volume: in press Issue: 6 Pages: 1064-71
- DOI
  10.1016/j.gie.2014.03.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590931, KAKENHI-PROJECT-25460923, KAKENHI-PROJECT-26460956
[Journal Article] microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1.2014
- Author(s)
  Fujiya M, Konishi H, Kamel M.K.M, Ueno N, Inaba Y, Moriichi K, Tanabe H, Ikuta K, Ohtake T, Kohgo Y.
- Journal Title
  
  Oncogene
  
  Volume: in press Issue: 40 Pages: 4847-56
- DOI
  10.1038/onc.2013.429
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931, KAKENHI-PROJECT-24790671, KAKENHI-PROJECT-26460956
[Journal Article] Probiotic treatments for induction and maintenance of remission in inflammatory bowel diseases: A meta-analysis of randomized controlled trials.2014
- Author(s)
  Fujiya M, Ueno N, Kohgo Y.
- Journal Title
  
  Clin J Gastroenterol
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1007/s12328-013-0440-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931
[Journal Article] TU-100 (Daikenchuto) and Ginger Ameliorate Anti-CD3 Antibody Induced T Cell-Mediated Murine Enteritis: Microbe-Independent Effects Involving Akt and NF-κB Suppression.2014
- Author(s)
  Ueno N, Hasebe T, Kaneko A, Yamamoto M, Wang Y, Fujiya M, Kohgo Y, Kono T, Musch MW, Chang EB.
- Journal Title
  
  PloS One
  
  Volume: 23 Issue: 5 Pages: e97456-e97456
- DOI
  10.1371/journal.pone.0097456
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460956
[Journal Article] Infliximab extends the duration until the first surgery in patients with Crohn's disease2013
- Author(s)
  Sakatani A, Fujiya M, Ito T, Inaba Y, Ueno N, Kashima S, Tominaga M, Moriichi K, Okamoto K, Tanabe H, Ikuta K, Ohtake T, Kono T, Furukawa H, Ashida T, Kohgo Y
- Journal Title
  
  Biomed Research International
  
  Volume: 2013 Pages: 879491-879491
- NAID
  120006517749
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Reduction of E-cadherin by Human Defensin-5 in Esophageal Squamous Cells.2013
- Author(s)
  Nomura Y, Tanabe H, Moriichi K, Igawa S, Ando K, Ueno N, Kashima S, Tominaga M, Goto T, Inaba Y, Ito T, Ishida-Yamamoto A, Fujiya M, Kohgo Y.
- Journal Title
  
  Biochem Bioph Res Co
  
  Volume: 439 Issue: 1 Pages: 71-77
- DOI
  10.1016/j.bbrc.2013.08.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931
[Journal Article] Reduction of E-cadherin by Human Defensin-5 in Esophageal Squamous Cells2013
- Author(s)
  Nomura Y, Tanabe H, Moriichi K, Igawa S, Ando K, Ueno N, Kashima S, Tominaga M, Goto T, Inaba Y, Ito T, Ishida-Yamamoto A, Fujiya M, Kohgo Y
- Journal Title
  
  Biochem Bioph Res Co
  
  Volume: 439(1) Pages: 71-77
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Infliximab extends the duration until the first surgery in patients with Crohn’s disease.2013
- Author(s)
  Sakatani A, Fujiya M, Ito T, Inaba Y, Ueno N, Kashima S, Tominaga M, Moriichi K, Okamoto K, Tanabe H, Ikuta K, Ohtake T, Kono T, Furukawa H, Ashida T, Kohgo Y.
- Journal Title
  
  Biomed Research International
  
  Volume: 2013 Pages: 879491-879491
- DOI
  10.1155/2013/879491
- NAID
  120006517749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931, KAKENHI-PROJECT-24790671
[Journal Article] microRNA-146b improves intestinal injury in mouse colitis by activating NF-kB and improving epithelial barrier function.2013
- Author(s)
  Nata T, Fujiya M, Ueno N, Moriichi K, Konishi H, Tanabe H, Ohtake T, Ikuta K, Kohgo Y.
- Journal Title
  
  Journal of Gene Medicine
  
  Volume: 15 Issue: 6-7 Pages: 249-260
- DOI
  10.1002/jgm.2717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931
[Journal Article] Back-to-Back Comparison of Auto-Fluorescence Imaging (AFI) versus High Resolution White Light Colonoscopy for Adenoma Detection.2012
- Author(s)
  Moriichi K, Fujiya M, Sato R, Watari J, Nomura Y, Nata T, Ueno N, Maeda S, Kashima S, Itabashi K, Ishikawa C, Inaba Y, Ito T, Okamoto K, Tanabe H, Mizukami Y, Saitoh Y, Kohgo Y.
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 12 Issue: 1 Pages: 75-75
- DOI
  10.1186/1471-230x-12-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931
[Journal Article] Pseudo-diverticular formation due to a cytomegalovirus infection in the colorectum.2012
- Author(s)
  Muto M, Sato R, Fujiya M, Tanaka K, Serikawa S, Hayashi A, Konno Y, Sakamoto J, Nishikawa T, Oikawa K, Ueno N, Ikuta K, Mizukami Y, Tanno S, Watari J, Kohgo Y.
- Journal Title
  
  Digestive Endoscopy
  
  Volume: 24 Issue: 3 Pages: 193-193
- DOI
  10.1111/j.1443-1661.2011.01188.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931
[Journal Article] Competence and sporulation factor derived from Bacillus subtilis improves epithelial cell injury in intestinal inflammation via immunomodulation and cytoprotection2012
- Author(s)
  Okamoto K, Fujiya M, Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y
- Journal Title
  
  Int J Colorectal Diseases
  
  Volume: (in press) Issue: 8 Pages: 1039-46
- DOI
  10.1007/s00384-012-1416-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-22590754, KAKENHI-PROJECT-23590931
[Journal Article] Competence and sporulation factor derived from Bacillus subtilis improves epithelial cell injury in intestinal inflammation via immunomodulation and cytoprotection2012
- Author(s)
  Okamoto K, Fujiya M, Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y
- Journal Title
  
  Int J Colorectal Diseases
  
  Volume: 27(8) Pages: 1039-46
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Heat-killed body of Lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function2011
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: 17(11) Pages: 2235-2250
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Probiotic-derived polyphosphate enhances the epithelial barrier function and maintains intestinal homeostasis through integrin-p38 MAPK pathway2011
- Author(s)
  Segawa S, Fujiya M, Konishi H, Ueno N, Kobayashi N, Shigyo T, Kohgo Y
- Journal Title
  
  PloS One
  
  Volume: 6(8)
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Obscure gastrointestinal bleeding occurring 50 years after an appendectomy2011
- Author(s)
  Kashima S, Nata T, Fujiya M, Moriichi K, Nomura Y, Ueno N, Itabashi K, Ishikawa C, Inaba Y, Ito T, Okamoto K, Mizukami Y, Ebisawa Y, Chisato N, Kono T, Tokusashi Y, Miyokawa N, Yamada M, Kohgo Y
- Journal Title
  
  Gut
  
  Volume: 60(10) Issue: 10 Pages: 1344-1344
- DOI
  10.1136/gut.2009.205526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Heat-killed body of Lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function.
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y.
- Journal Title
  
  Inflammatory Bowel Diseases
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148
[Journal Article] Musch MW, Chang EB. Daikenchuto, a Japanese traditional medicine, blocks DSS-induced intestinal inflammation and damage
- Author(s)
  Ueno N, Hasebe T, Kaneko A, Yamamoto M, Wang Y, Fujiya M, Kohgo Y, Kono T
- Journal Title
  
  PloS One
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22390148
[Patent] 腸管保護剤2014
- Inventor(s)
  高後裕,藤谷幹浩,上野伸展,瀬川修一,小林直之
- Industrial Property Rights Holder
  旭川医科大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2014-04-15
- Data Source
  KAKENHI-PROJECT-22390148
[Patent] 腸管保護剤2011
- Inventor(s)
  高後裕,藤谷幹浩,上野伸展,瀬川修一,小林直之
- Industrial Property Rights Holder
  旭川医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-03-28
- Overseas
- Data Source
  KAKENHI-PROJECT-22390148
[Patent] 特許2010
- Inventor(s)
  高後裕, 藤谷幹浩, 上野伸展, 瀬川修一, 小林直之
- Industrial Property Rights Holder
  国立大学法人旭川医科大学,サッポロビール株式会社
- Industrial Property Number
  2010-089469
- Filing Date
  2010-04-08
- Acquisition Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 乳酸菌由来長鎖ポリリン酸は血小板活性化を介して腸管上皮の創傷治癒を促進する2020
- Author(s)
  磯崎翔太郎、藤谷幹浩、小西弘晃、田中宏樹、村上雄紀、杉山雄哉、安藤勝祥、上野伸展、後藤拓磨、嘉島伸、高氏修平、盛一健太郎、田邊裕貴、水上裕輔、奥村利勝
- Organizer
  第57回消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07927
[Presentation] 乳酸菌由来分子を用いた新規炎症性腸疾患治療薬の開発2018
- Author(s)
  藤谷幹浩、上野伸展、嘉島伸、田中一之、坂谷慧、垂石正樹、奥村利勝
- Organizer
  厚生労働科学研究難治性疾患克服研究事業「難治性炎症性腸管障害に関する調査研究」平成29年度第2 回総会
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] 乳酸菌由来分子を用いた新規炎症性腸疾患治療薬の開発2017
- Author(s)
  藤谷幹浩、上野伸展、嘉島伸、田中一之、坂谷慧、垂石正樹、奥村利勝．
- Organizer
  厚生労働科学研究難治性疾患克服研究事業「難治性炎症性腸管障害に関する調査研究」平成29年度第1回総会
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] 乳酸菌由来フェリクロームによる抗腫瘍メカニズムの解析2017
- Author(s)
  井尻学見、藤谷幹浩、上野伸展、奥村利勝
- Organizer
  第45回日本消化器免疫学会
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Ferrichrome, a tumor suppressive molecule derived from Lactobacillus casei, inhibits the progression of colorectal cancer via the endoplasmic reticulum stress pathway.2017
- Author(s)
  Konishi H, Fujiya M, Ijiri M, Tanaka K, Fujibayashi S, Goto T, Kashima S, Ando K, Takahashi K, Ueno N, Sasajima J, Moriichi K, Tanaka H, Ikuta K, Okumura T.
- Organizer
  DDW 2017 (AGA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] PD.1 Translational medicineへの展開を目指した腸疾患研究「菌由来の活性物質であるポリリン酸を用いた新規炎症性腸疾患治療薬の開発」2016
- Author(s)
  上野伸展、藤谷幹浩．
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] 菌由来の活性物質であるポリリン酸を用いた新規炎症性腸疾患治療薬の開発2016
- Author(s)
  上野伸展、藤谷幹浩．
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Evaluation of the disease activity in UC by white light and autofluorescence imaging.2016
- Author(s)
  Ijiri M, Fujiya M, Iwama T, Sakatani A, Ueno N, Okumura T.
- Organizer
  The 4th Annual Meeting of Asian Organization for Crohn’s & Colitis
- Place of Presentation
  Kyoto
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] The pre-operative use of infliximab prevents the shortening of the small intestine in patients with Crohn’s disease.2016
- Author(s)
  Sakatani A, Fujiya M, Iwama T, Ijiri M, Ueno N, Okumura T.
- Organizer
  The 4th Annual Meeting of Asian Organization for Crohn’s & Colitis
- Place of Presentation
  Kyoto
- Year and Date
  2016-07-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Evaluation of disease activity in patients with UC by white light, magnifying and autofluorescence imaging.2016
- Author(s)
  Moriichi K, Fujiya M, Iwama T, Sato H, Utsumi T, Ijiri M, Tanaka K, Sakatani A, Fujibayashi S, Nomura Y, Ueno N, Kashima S, Goto T, Sasajima J.
- Organizer
  DDW 2016 (ASGE)
- Place of Presentation
  San Diego
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] 乳酸菌由来長鎖ポリリン酸による腸管免疫の制御2015
- Author(s)
  藤谷幹浩、嘉島　伸、小西弘晃、上野伸展、高後　裕．
- Organizer
  第52回日本消化器免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2015-07-30
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Long-term oral dietary administration of a new probiotic, Lactobacillus brevis SBC8803, alters gut the microbiota and ameliorates DSS-induced colitis in mice.2014
- Author(s)
  Ueno N, Fujiya M, Segawa S, Konishi H, Sakatani A, Tanaka K, Dokoshi T, Ando K, Kashima S, Inaba Y, Ito T, Moriichi K, Shigyo T, Kohgo Y.
- Organizer
  DDW 2014 (AGA)
- Place of Presentation
  Chicago
- Year and Date
  2014-05-06
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Long-term oral dietary administration of a new probiotic, Lactobacillus brevis SBC8803, alters gut the microbiota and ameliorates DSS-induced colitis in mice.2014
- Author(s)
  Ueno N, Fujiya M, Segawa S, Konishi H, Sakatani A, Tanaka K, Dokoshi T, Ando K, Kashima S, Inaba Y, Ito T, Moriichi K, Shigyo T, Kohgo Y.
- Organizer
  DDW 2014 (AGA)
- Place of Presentation
  Chicago
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Long-term oral dietary administration of a new probiotic, Lactobacillus brevis SBC8803, alters gut the microbiota and ameliorates DSS-induced colitis in mice2014
- Author(s)
  Ueno N, Fujiya M, Segawa S, Konishi H, Sakatani A, Tanaka K, Dokoshi T, Ando K, Kashima S, Inaba Y, Ito T, Moriichi K, Shigyo T, Kohgo Y
- Organizer
  DDW 2014 (AGA)
- Place of Presentation
  Chicago
- Year and Date
  2014-05-06
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Host-microbial interaction in BD」A novel host-microbial interaction via the uptake of probiotic-derived molecules by intestinal epithelia.2014
- Author(s)
  Fujiya M, Ueno N, Kohgo Y.
- Organizer
  JDDW 2014 (第56回日本消化器病学会、第88回日本消化器内視鏡学会、第12回日本消化器外科学会)
- Place of Presentation
  Kobe
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] A probiotic-derived polyphosphate improves the fibrosis in a murine model of chronic colitis via the regulation of inflammation- and fibrosis-associated mediators.2014
- Author(s)
  Fujiya M, Konishi H, Ueno N, Inaba Y, Moriichi K, Kohgo Y.
- Organizer
  GI Research Academy 2014
- Place of Presentation
  Tokyo
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Oral dietary administration of heat-killed Lactobacillus brevis SBC8803 alters the gut microbiome and ameliorates experimental colitis in mice.2014
- Author(s)
  Ueno N, Fujiya M, Konishi H, Sakatani A, Tanaka K, Dokoshi T, Ando K, Kashima S, Inaba Y, Moriichi K, Kohgo Y.
- Organizer
  2014 Advanced in Inflammatory Bowel Disease
- Place of Presentation
  Orland
- Year and Date
  2014-12-04
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] MicroRNA-18a induces apoptosis in colon cancer cells through the autophagosomal degradation of hnRNP A1.2014
- Author(s)
  Konishi H, Fujiya M, Ando K, Tanaka K, Sakatani A, Dokoshi T, Inaba Y, Fujibayashi S, Goto T, Kashima S, Ueno N, Sasajima J, Ito T, Tanaka H, Ikuta K, Kohgo Y.
- Organizer
  DDW 2014 (AGA)
- Place of Presentation
  Chicago
- Year and Date
  2014-05-06
- Data Source
  KAKENHI-PROJECT-26460956
[Presentation] Treatment with the heat-killed body of Lactobacillus brevis SBC8803 ameliorates intestinal injury in a dextran sulfate sodium-induced chronic colitis model by enhancing the intestinal barrier function.2013
- Author(s)
  Ueno N, Fujiya M, Segawa S, Dokoshi T, Ando K, Inaba Y, Moriichi K, Tanabe H, Kobayashi N, Shigyo T, Kohgo Y.
- Organizer
  1st annual meeting of Asian Organization for Crohn's & Colitis (AOCC)
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] A probiotic-derived polyphosphate improves chronic inflammation and fibrosis via caveolin-dependent endocytosis.2013
- Author(s)
  Konishi H, Fujiya M, Segawa S, Kashima S, Ueno N, Tanaka K, Sakatani A, Dokoshi T, Ando K, Tominaga M, Inaba Y, Ito T, Tanabe H, Moriichi K, Kohgo Y.
- Organizer
  DDW 2013 (AGA)
- Place of Presentation
  Orland
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Probiotic-derived polyphosphate inhibits colon cancer progression through the inactivation of the ERK pathway and the induction of cancer cell apoptosis.2013
- Author(s)
  Sakatani A, Fujiya M, Konishi H, Segawa S, Kashima S, Ueno N, Tanaka K, Dokoshi T, Ando K, Tominaga M, Inaba Y, Ito T, Tanabe H, Moriichi K, Kohgo Y.
- Organizer
  DDW 2013 (AGA)
- Place of Presentation
  Orland
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] A probiotic-derived polyphosphate improves chronic inflammation and fibrosis via caveolin-dependent endocytosis2013
- Author(s)
  Konishi H, Fujiya M, Segawa S, Kashima S, Ueno N, Tanaka K, Sakatani A, Dokoshi T, Ando K, Tominaga M, Inaba Y, Ito T, Tanabe H, Moriichi K, Kohgo Y
- Organizer
  DDW 2013 (AGA)
- Place of Presentation
  Orland
- Year and Date
  2013-05-21
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] A probiotic-derived polyphosphate improves chronic inflammation and fibrosis via caveolin-dependent endocytosis.2013
- Author(s)
  Fujiya M, Segawa S, Ueno N, Inaba Y, Moriichi K, Kohgo Y.
- Organizer
  GI Research Academy 2013
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Probiotic-derived polyphosphate inhibits colon cancer progression through the inactivation of the ERK pathway and the induction of cancer cell apoptosis2013
- Author(s)
  Sakatani A, Fujiya M, Konishi H, Segawa S, Kashima S, Ueno N, Tanaka K, Dokoshi T, Ando K, Tominaga M, Inaba Y, Ito T, Tanabe H, Moriichi K, Kohgo Y
- Organizer
  DDW 2013 (AGA)
- Place of Presentation
  Orland
- Year and Date
  2013-05-21
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Polyphosphate is a novel active molecule derived from Lactobacillus brevis that contributes to the maintenance of intestinal homeostasis and the improvement of intestinal injury in acute and chronic experimental colitis2012
- Author(s)
  Fujiya M, Ueno N, Sakatani A, Dokoshi T, Ando K, Nomura Y, Kashima S, Tominaga M, Inaba Y, Ito T, Moriichi K, Kikuchi Y, Okamoto K, Tanabe H, Segawa S, Kobayashi N, Shigyo T, Kohgo Y
- Organizer
  DDW 2012 (AGA)
- Place of Presentation
  San Diego
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] The novel host-probiotics interaction through activation of intestinal epithelial autophagy2012
- Author(s)
  Inaba Y, Fujiya M, Ueno N, Chang EB, Kohgo Y
- Organizer
  The 5th Korea-Japan Inflammatory Bowel Disease Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2012-01-28
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Lactobacillus brevis Culture Supernatant Induces Cytoprotective Small Heat Shock Protein HSP27 and Increase Intestinal Barrier Function by Activating the p38 MAPK Pathway2011
- Author(s)
  Segawa S, Fujiya M, Konishi H, Ueno N, Kobayashi N, Shigyo T, Kohgo Y
- Organizer
  15th International Congress of Mucosal Immunology (ICMI2011)
- Place of Presentation
  Paris
- Year and Date
  2011-07-05
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 麦芽乳酸菌(Lactobacillus brevis)SBC8803死菌はDSS慢性腸炎モデルマウスを改善する2011
- Author(s)
  安藤勝祥, 上野伸展, 藤谷幹浩, 瀬川修一, 稲場勇平, 盛一健太郎, 高後裕
- Organizer
  第48回日本消化器免疫学会総会
- Place of Presentation
  金沢
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 麦芽乳酸菌(Lactobacillus brevis)SBC8803死菌の生理活性の解明2011
- Author(s)
  藤谷幹浩, 上野伸展, 高後裕
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 腸内細菌由来のポリ燐酸を介した新しい宿主-細菌相互作用の解明と腸炎治療への応用2011
- Author(s)
  藤谷幹浩, 上野伸展, 瀬川修一, 稲場勇平, 岡本耕太郎, 高後裕
- Organizer
  第19回浜名湖シンポジウム
- Place of Presentation
  浜松
- Year and Date
  2011-12-23
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Lactobacillus brevis Culture Supernatant Induces Cytoprotective Small Heat Shock Protein HSP27 and Increase Intestinal Barrier Function by Activating the p38 MAPK Pathway2011
- Author(s)
  Segawa S, Fujiya M, Konishi H, Ueno N, Kobayashi N, Shigyo T, Kohgo Y
- Organizer
  15th International Congress of Mucosal Immunology (ICMI 2011)
- Place of Presentation
  Paris
- Year and Date
  2011-07-05
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] シンポジウム「小腸病態研究の進歩一腸内細菌と免疫応答」新規乳酸菌由来の活性物質による腸管保護作用の解析と腸炎治療への応用2011
- Author(s)
  藤谷幹浩、上野伸展、瀬川修一、稲場勇平、岡本耕太郎、高後裕
- Organizer
  第49回小腸研究会
- Place of Presentation
  東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Lactobacillus Brevis SBC8803 Culture Supernatant Induces Cytoprotective Small Heat Shock Protein HSP27 in Human Intestinal Epithelial CaCo2/Bbe Cells by ctivating the p38 MAPK Pathway and Alleviates DSS-Induced Acute Colitis in C57BL/6 Mice2010
- Author(s)
  Segawa S, Fujiya M, Ueno N, Kobayashi N, Ito K, Kohgo Y
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Heat-Killed Body of Lactobacillus brevis SBC8803 Contributes to Maintain Intestinal Homeostasis and Improve Intestinal Injury in a Murine Model of Colitis.2010
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Inaba Y, Moriichi K, Tanabe H, Mizukami. Y, Kobayashi N, Ito K, Kohgo Y.
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Heat-killed Lactobaccilus brevis SBC8803 improves intestinal injury in a murine model of colitis by protecting the intestinal epithelia and regulating pro-inflammatory cytokines.2010
- Author(s)
  Ueno N, Fujiya M, Kohgo Y.
- Organizer
  2nd International Forum (Japanese Society of Gastroenteroloey)
- Place of Presentation
  Niigata
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Heat-Killed Body of Lactobacillus brevis SBC8803 Contributes to Maintain Intestinal Homeostasis and Improve Intestinal Injury in a Murine Model of Colitis.2010
- Author(s)
  Ueno N, Fujiya M, Kohgo Y.
- Organizer
  US-Japan GI Excutive meeting
- Place of Presentation
  Tokyo
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Competence and Sporulation Factor Derived From Bacillus Subtilis Improves Epithelial Cell Injury in Intestinal Inflammation via Immunomodulation and Cytoprotection2010
- Author(s)
  Okamoto K, Fujiya M, Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Heat-Killed Body of Lactobacillus brevis SBC8803 Contributes to Maintain Intestinal Homeostasis and Improve Intestinal Injury in a Murine Model of Colitis2010
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Inaba Y, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Lactobacillus Brevis SBC8803 Culture Supernatant Induces Cytoprotective Small Heat Shock Protein HSP27 in Human Intestinal Epithelial CaCo2/Bbe Cells by ctivating the p38 MAPK Pathway and Alleviates DSS-Induced Acute Colitis in C57BL/6 Mice.2010
- Author(s)
  Segawa S, Fujiya M, Ueno N, Kobayashi N, Ito K, Kohgo Y.
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 慢性腸炎における腸管障害や線維化に対する乳酸菌由来長鎖ポリリン酸の有用性
- Author(s)
  嘉島伸，藤谷幹浩，上野伸展，井尻学見，岡田哲弘、坂谷慧，田中一之，堂腰達矢，安藤勝祥，富永素矢，稲場勇平，伊藤貴博，田邊裕貴，高後裕
- Organizer
  第99回日本消化器病学会総会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Polyphosphate is a novel active molecule derived from Lactobacillus brevis that contributes to the maintenance of intestinal homeostasis and the improvement of intestinal injury in acute and chronic experimental colitis.
- Author(s)
  Fujiya M, Ueno N, Sakatani A, Dokoshi T, Ando K, Nomura Y, Kashima S, Tominaga M, Inaba Y, Ito T, Moriichi K, Kikuchi Y, Okamoto K, Tanabe H, Segawa S, Kobayashi N, Shigyo T, Kohgo Y.
- Organizer
  DDW 2012 (AGA)
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] 乳酸菌由来長鎖ポリリン酸による慢性腸炎および腸管線維化の改善効果．
- Author(s)
  藤谷幹浩、小西弘晃，嘉島　伸，瀬川修一、上野伸展，稲場勇平，岡本耕太郎，高後　裕．
- Organizer
  第50回小腸研究会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Polyphosphate derived from Lactobacillus contributes to the maintenance of intestinal homeostasis and the improvement of intestinal injury in experimental colitis.
- Author(s)
  Fujiya M, Segawa S, Ueno N, Inaba Y, Moriichi K, Tanabe H, Kohgo Y.
- Organizer
  10th Asian IBD Symposium
- Place of Presentation
  Seoul
- Data Source
  KAKENHI-PROJECT-22390148
[Presentation] Oral dietary administration of heat-killed Lactobacillus brevis SBC8803 alters the gut microbiome and ameliorates experimental colitis in mice
- Author(s)
  Nobuhiro Ueno
- Organizer
  Crohn's and Colitis Foundation of America (CCFA)
- Place of Presentation
  orlando. FL. USA
- Year and Date
  2014-12-04 – 2014-12-06
- Data Source
  KAKENHI-PROJECT-26860490
[Presentation] A polyphosphate derived from Lactobacillus brevis improves the intestinal barrier function and injury in acute and chronic experimental colitis.
- Author(s)
  Fujiya M, Konishi H, Ueno N, Inaba Y, Ito T, Moriichi K, Tanabe H, Segawa S, Shigyo T, Kohgo Y.
- Organizer
  13th International Conference of FFC
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-22390148

1. FUJIYA Mikihiro (80322915)

# of Collaborated Projects: 5 results

# of Collaborated Products: 75 results
2. Moriichi Kentaro (70455715)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
3. Takauji Shuhei (20793897)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 小西弘晃 (30777181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
5. KOHGO Yutaka (10133183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 44 results
6. ASHIDA Toshifumi (50261409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. OHTAKE Takaaki (10359490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. MAEMOTO Atsuo (40400113)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 稲場勇平 (30447099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
10. 堂腰達矢 (50624178)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂谷慧 (20624175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 井川哲子 (30548821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 安藤勝祥

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 水上裕輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 笹島順平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

UENO NOBUHIRO 上野 伸展

UENO Nobuhiro 上野 伸展

Research Projects

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Reg3を介した皮膚腸管連関の制御機構解明

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A research on ARDS treatment based on the mechanism of gut-lung axis by molecules derived from probiotics

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Identifications and functional analyses of beneficial bacteria-derived bioactive molecules

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Novel therapy for sepsis with probiotic-derived intestinal barriers enhancing molecules

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Development of novel preventive and therapeutic substance derived from oral flora or probiotics

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An analysis of the mechanisms through which bacteria-derived bioactive molecules protect the intestine in enteritis models and primary cultured cells

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The alteration of microbiota and the efficiency of treatment for IBS model mice by the novel probiotics, Lactobacillus brevis SB88Principal Investigator

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Cytoprotective effects of bioactive molecules derived from bacteria in the intestinal biofilm

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[Journal Article] Polyphosphate, derived from the probiotic Lactobacillus brevis, modulates the intestinal microbiome and attenuates acute pancreatitis.2021

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[Journal Article] Bacteria-derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis-associated cancer.2021

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[Journal Article] Probiotic Aspergillus oryzae produces anti-tumor mediator and exerts anti-tumor effects in pancreatic cancer through the p38 MAPK signaling pathway.2021

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[Journal Article] Probiotic derived polyphosphate accelerates intestinal epithelia wound healing through inducing platelet-derived mediators.2021

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[Journal Article] Probiotic-derived ferrichrome inhibits the growth of refractory pancreatic cancer cells.2020

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[Journal Article] A Case of Alpha-Fetoprotein-Producing Adenocarcinoma of the Esophagogastric Junction in which Long-Term Survival Was Achieved by Means of Individualized Multidisciplinary Therapy2018

Author(s)

UENO NOBUHIRO 上野伸展

UENO Nobuhiro 上野伸展