• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

KOHYAMA JUN  神山 淳

ORCIDConnect your ORCID iD *help
… Alternative Names

神山 淳  コウヤマ ジュン

KOHYAMA Jun  神山 淳

Less
Researcher Number 30437511
Other IDs
Affiliation (Current) 2023: 慶應義塾大学, 医学部(信濃町), 准教授
Affiliation (based on the past Project Information) *help 2019 – 2022: 慶應義塾大学, 医学部(信濃町), 准教授
2016 – 2017: 慶應義塾大学, 医学部(信濃町), 准教授
2015 – 2016: 慶應義塾大学, 医学部, 准教授
2014: 慶應義塾大学, 医学部, 特任講師
2007 – 2009: Nara Institute of Science and Technology, バイオサイエンス研究科, 助教
2008: 奈良先端科技大, バイオサイエンス研究科, 助教
Review Section/Research Field
Principal Investigator
Nerve anatomy/Neuropathology / General medical chemistry / Orthopaedic surgery / Pathological medical chemistry / Basic Section 52050:Embryonic medicine and pediatrics-related
Keywords
Principal Investigator
神経幹細胞 / アストロサイト / エピジェネティクス / 骨形成因子 / REST / NRSF / 胚性幹細胞 / DNAメチル化 / ES細胞 / アストロサイ … More / 脊髄損傷 / Notchシグナル / 神経科学 / オリゴデンドロサイト前駆細胞 / 細胞間相互作用 / 神経変性疾患 / バイオインフォマティクス / ニューロン / 試験管内モデル / 共培養 / シグナル伝達 / iPS細胞 / 脳オルガノイド / iPS細胞由来脳オルガノイド / CHARGE症候群 / CHARGE症候群 / iPS細胞由来脳オルガノイド溝田 / 1細胞RNA-Seq / 1細胞ATAC-Seq Less
  • Research Projects

    (5 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (8 People)
  •  Unraveling mechanism of pathogenesis in CHAREGE syndrome using iPSC-derived brain organoidPrincipal Investigator

    • Principal Investigator
      神山 淳
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Keio University
  •  Development of new technology to analyze cellular interaction between neuron and glial cellsPrincipal Investigator

    • Principal Investigator
      KOHYAMA JUN
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Keio University
  •  Crosstalk between immune system and nervous system in the pathogenesis of spinal cord injuryPrincipal Investigator

    • Principal Investigator
      KOHYAMA JUN
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University
  •  Site-specific epigenetic regulation in cell fate decision of neural progenitor cellsPrincipal Investigator

    • Principal Investigator
      KOHYAMA Jun
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General medical chemistry
    • Research Institution
      Nara Institute of Science and Technology
  •  神経系細胞の分化形質及び可塑性を規定する分子群の解析Principal Investigator

    • Principal Investigator
      神山 淳
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Nerve anatomy/Neuropathology
    • Research Institution
      Nara Institute of Science and Technology

All 2022 2020 2018 2017 2016 2015 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury2022

    • Author(s)
      Kitagawa Takahiro、Nagoshi Narihito、Kamata Yasuhiro、Kawai Momotaro、Ago Kentaro、Kajikawa Keita、Shibata Reo、Sato Yuta、Imaizumi Kent、Shindo Tomoko、Shinozaki Munehisa、Kohyama Jun、Shibata Shinsuke、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki
    • Journal Title

      Stem Cell Reports

      Volume: 17 Pages: 127-142

    • DOI

      10.1016/j.stemcr.2021.12.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03623, KAKENHI-PROJECT-19H03983
  • [Journal Article] Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury2022

    • Author(s)
      Shibata Reo、Nagoshi Narihito、Kajikawa Keita、Ito Shuhei、Shibata Shinsuke、Shindo Tomoko、Khazaei Mohamad、Nori Satoshi、Kohyama Jun、Fehlings Michael G.、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki
    • Journal Title

      Journal of Neurotrauma

      Volume: 39 Pages: 667-682

    • DOI

      10.1089/neu.2021.0225

    • Data Source
      KAKENHI-PROJECT-19H03623
  • [Journal Article] A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury2020

    • Author(s)
      Kamata Yasuhiro、Isoda Miho、Sanosaka Tsukasa、Shibata Reo、Ito Shuhei、Okubo Toshiki、Shinozaki Munehisa、Inoue Mitsuhiro、Koya Ikuko、Shibata Shinsuke、Shindo Tomoko、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki、Nagoshi Narihito、Kohyama Jun
    • Journal Title

      STEM CELLS Translational Medicine

      Volume: 10 Pages: 398-413

    • DOI

      10.1002/sctm.20-0269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03623, KAKENHI-PROJECT-18K14840
  • [Journal Article] Chromatin remodeler CHD7 regulates the stem cell identity of human neural progenitors2018

    • Author(s)
      Chai MuhChyi、Sanosaka Tsukasa、Okuno Hironobu、Zhou Zhi、Koya Ikuko、Banno Satoe、Andoh-Noda Tomoko、Tabata Yoshikuni、Shimamura Rieko、Hayashi Tetsutaro、Ebisawa Masashi、Sasagawa Yohei、Nikaido Itoshi、Okano Hideyuki、Kohyama Jun
    • Journal Title

      Genes & Development

      Volume: 32 Pages: 165-180

    • DOI

      10.1101/gad.301887.117

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26713047, KAKENHI-PROJECT-16K15240
  • [Journal Article] Low immunogenicity of mouse induced pluripotent stem cell-derived neural stem/progenitor cells2017

    • Author(s)
      Itakura Go、Ozaki Masahiro、Nagoshi Narihito、Kawabata Soya、Nishiyama Yuichiro、Sugai Keiko、Iida Tsuyoshi、Kashiwagi Rei、Ookubo Toshiki、Yastake Kaori、Matsubayashi Kohei、Kohyama Jun、Iwanami Akio、Matsumoto Morio、Nakamura Masaya、Okano Hideyuki
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 1-13

    • DOI

      10.1038/s41598-017-13522-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26713047
  • [Journal Article] Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells2017

    • Author(s)
      Iida T, Iwanami A, Sanosaka T, Kohyama J, Miyoshi H, Nagoshi N, Kashiwagi R, Toyama Y, Matsumoto M, Nakamura M, Okano H.
    • Journal Title

      STEM CELLS

      Volume: 35 Pages: 1316-1327

    • DOI

      10.1002/stem.2581

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10422, KAKENHI-PROJECT-26713047
  • [Journal Article] Grafted Human iPS Cell-Derived Oligodendrocyte Precursor Cells Contribute to Robust Remyelination of Demyelinated Axons after Spinal Cord Injury.2016

    • Author(s)
      Kawabata S, Takano M, Numasawa-Kuroiwa Y, Itakura G, Kobayashi Y, Nishiyama Y, Sugai K, Nishimura S, Iwai H, Isoda M, Shibata S, Kohyama J, Iwanami A, Toyama Y, Matsumoto M, Nakamura M, Okano H,
    • Journal Title

      Stem Cell Reports

      Volume: 6(1) Pages: 1-8

    • DOI

      10.1016/j.stemcr.2015.11.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462714, KAKENHI-PROJECT-26713047
  • [Journal Article] TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus.2015

    • Author(s)
      Matsuda T., Murao N., Katano Y., Juliandi B., Kohyama J., Akira S., Kawai T. & Nakashima K
    • Journal Title

      Nature communications

      Volume: 6 Pages: 1-10

    • DOI

      10.1038/ncomms7514

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-13J09007, KAKENHI-PUBLICLY-25110721, KAKENHI-PUBLICLY-25123714, KAKENHI-PROJECT-26670236, KAKENHI-PROJECT-26713047, KAKENHI-PUBLICLY-15H01381, KAKENHI-PROJECT-15H06474, KAKENHI-PROJECT-26293107
  • [Journal Article] BMP-induced REST regulates the establishment and maintenance of astrocytic identity.2010

    • Author(s)
      Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H, Nakashima K.
    • Journal Title

      J Cell Biol. 189(1)

      Pages: 159-170

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790230
  • [Journal Article] Astrocyte differentiation of neural precursor cells is enhanced by retinoic acid through a change in epigenetic modification.2009

    • Author(s)
      Asano H, Aonuma M, Sanosaka T, Kohyama J, Namihira M, Nakashima K.
    • Journal Title

      Stem Cells. 27(11)

      Pages: 2744-2752

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790230
  • [Journal Article] MeCP2は成体脳における分化可塑性を制御する2009

    • Author(s)
      神山淳, 中島欽一
    • Journal Title

      実験医学 27(6)

    • Data Source
      KAKENHI-PROJECT-20790230
  • [Journal Article] Neuronal differentiation of neural precursor cells is promoted by the methyl-CpG-binding protein MeCP22009

    • Author(s)
      Tsujimura K, Abematsu M, Kohyama J, Namihira M, Nakashima K.
    • Journal Title

      Exp Neurol. 219(1)

      Pages: 104-111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790230
  • [Journal Article] Epigenetic mechanisms regulating neural cell fate determination.2009

    • Author(s)
      Nakashima K, Kohyama J, Namihira M, Gage FH, Okano H, Sawamoto K.
    • Journal Title

      No To Hattatsu. 41(6)

      Pages: 411-414

    • NAID

      10026133121

    • Data Source
      KAKENHI-PROJECT-20790230
  • [Presentation] マウス脊髄損傷モデルにおけるエピジェネティック修飾関連因子の解析

    • Author(s)
      43.堀桂子, 神山淳, 坂野聡重, 岩波明生, 岡野栄之, 戸山芳昭, 中村雅也
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      城山観光ホテル(鹿児島県鹿児島市)
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-26713047
  • 1.  IWANAMI Akio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  OKANO Hideyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  NAKAMURA Masaya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  IIDA Tsuyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  KAWAI Taro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  芝田 晋介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  中島 欽一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  松田 泰斗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to connect your ORCID iD to this researcher?
* This action can be performed only by the researcher themselves.

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi