Watanabe Yoshihiro 渡部佳弘

… Alternative Names

WATANABE YOSHIHIRO 渡部佳弘

WATANABE Yoshihiro 渡部佳弘

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Researcher Number	30445374
Other IDs	https://orcid.org/0000-0002-1582-1245
Affiliation (Current)	2025: 国際医療福祉大学, 国際医療福祉大学成田病院, 講師
Affiliation (based on the past Project Information) *help	2024: 国際医療福祉大学, 国際医療福祉大学成田病院, 講師 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 共同研究員 2015 – 2016: 慶應義塾大学, 医学部, 助教 2015: 慶應義塾大学, 医学部, 共同研究員 2012 – 2013: 慶應義塾大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator ELPS / TORS / 経口的手術 / 咽喉頭腫瘍 / 頭頸部内視鏡手術 / 中咽頭顔 / 下咽頭顔 / 中咽頭癌 / 下咽頭癌 / 経口切除 … More / COX2 / TOVS / 頭頸部癌 / 咽頭癌 … More Except Principal Investigator 癌幹細胞 / 頭頸部癌 / EMT（上皮間葉転換） / 頸部リンパ節転移 / 多変量解析 / Cox2 / E-cadherin / 転移 / 頭頸部扁平上皮癌 / 低酸素応答因子 / 低酸素誘導因子 / 転写因子 / 唾液腺癌 / Flt-4 / 間葉上皮転換（MET） / EMT（上皮-間葉移行） / 頭頸部扁平上皮癌（HNSCC） / 分子標的治療 / 癌転移 / 上皮間葉移行 / 後発性リンパ節転移 / 細胞遊走運動 / 独立予後因子 / 生存率 / 転写抑制因子 / 細胞遊走能 / EMT(上皮間葉転換) Less

Research to improve the technique and introduce safety of endoscopic laryngopharyngeal surgeryPrincipal Investigator
- Principal Investigator
  
  渡部佳弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  International University of Health and Welfare
Analysis of COX-2 expression and elucidation of anticancer drug resistance mechanism in head and neck cancersPrincipal Investigator
- Principal Investigator
  
  WATANABE YOSHIHIRO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Analysis of HIF1-alpa expression for head and neck cancer metastasis
- Principal Investigator
  
  Ozawa Hiroyuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Control of metastasis and cancer stem-like cell property by inducing MET (mesenchymal-epithelial transition) in head and neck cancer
- Principal Investigator
  
  IMANISHI YORIHISA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
  Kyorin University
A study of head and neck cancer treatment targeting signaling pathway to induce the cancer stem cells and the Epithelial-mesenchymal transition
- Principal Investigator
  
  SATO Yoichiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University
Study to control metastasis of HNSCC by targeting molecular mechanisms leading to epithelial-mesenchymal transition (EMT)
- Principal Investigator
  
  IMANISHI Yorihisa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Keio University

All 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ　oral tongue squamous cell carcinoma2015
- Author(s)
  Noboru Habu
- Journal Title
  
  BMC cancer
  
  Volume: 18 Issue: 1 Pages: 730-730
- DOI
  10.1186/s12885-015-1732-9
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25861587, KAKENHI-PROJECT-24592614, KAKENHI-PROJECT-25462692
[Journal Article] Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma2014
- Author(s)
  Ryoichi Fujii, Yorihisa Imanishi, Katsushi Shibata, Nobuya Sakai, Koji Sakamoto, Seiji Shigetomi, Noboru Habu, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Hiroyuki Ozawa, Toshiki Tomita, Kaori Kameyama, Masato Fujii, and Kaoru Ogawa
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 33 Issue: 1 Pages: 40-40
- DOI
  10.1186/1756-9966-33-40
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462692
[Journal Article] 経口直達的下咽頭喉頭部分切除術における手技的工夫2013
- Author(s)
  今西順久，羽生　昇，佐藤陽一郎，渡部佳弘，他
- Journal Title
  
  頭頸部外科
  
  Volume: 23 Pages: 181-191
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] The Cox2 and EP2 inhibition suppress EMT and the expression of Cox2 and E-cadherin involved into pharyngeal carcinoma2017
- Author(s)
  渡部佳弘
- Organizer
  第76回日本癌学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] 咽頭扁平上皮癌におけるCox2及びEP2選択的阻害によるEMT抑制効果とE-cadherinとCox2発現の2017
- Author(s)
  渡部佳弘
- Organizer
  第118回日本耳鼻咽喉科学会
- Place of Presentation
  広島国際会議場・ANAクラウンプラザホテル広島（広島県広島市）
- Year and Date
  2017-05-19
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] Anti-cancer effects of selective Cox-2 and EP2 inhibition through suppression of EMT and the clinical implications of overexpression of Cox-2 and downregulation of E-cadherin in pharyngeal squamous cell carcinoma2017
- Author(s)
  Yoshihiro Watanabe
- Organizer
  American Association for Cancer Research annual meeting 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] 咽頭扁平上皮癌におけるCox2及びEP2選択的阻害によるEMT抑制効果とE-cadherinとCox2発現の評価2017
- Author(s)
  渡部佳弘
- Organizer
  第118回日本耳鼻咽喉科学会
- Invited
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] The functional and clinicopathological analysis of hypoxia inducible factor-1α (HIF1-α) in head and neck squamous cell carcinoma.2017
- Author(s)
  Ikari Y, Ozawa H, Imanishi Y, Tomita T, Sekimizu M, Watanabe Y, Ito F, Saito S, Ogawa K
- Organizer
  AACR annual meeting 2017
- Place of Presentation
  Washington DC, USA
- Year and Date
  2017-04-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462623
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞マーカーの発現とその臨床的意義に関する検討2016
- Author(s)
  羽生　昇，今西順久，坂本耕二，藤井良一，重冨征爾，大塚邦憲，佐藤陽一郎，渡部佳弘，徳丸　裕，藤井正人，小川　郁
- Organizer
  第22回東大・慶應ジョイントカンファレンス
- Place of Presentation
  興和創薬本社ホール（東京都中央区）
- Year and Date
  2016-02-18
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] Expression of stem cell markers Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delayed neck metastasis in stage I/II tongue squamous cell carcinoma2016
- Author(s)
  Noboru Habu, Yorihisa Imanishi, Kaori Kameyama, Masayuki Shimoda, Yutaka Tokumaru, Koji Sakamoto, Ryoichi Fujii, Seiji Shigetomi, Kuninori Otsuka, Yoichiro Sato, Yoshihiro Watanabe, Hiroyuki Ozawa, Toshiki Tomita, Masato Fujii, Kaoru Ogawa
- Organizer
  American Association for Cancer Research (AACR) 2016 Annual Meeting
- Place of Presentation
  New Orleans (USA)
- Year and Date
  2016-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 咽頭扁平上皮癌におけるCox2-inhibitionとE-cadherin発現制御に関する検討2016
- Author(s)
  渡部佳弘
- Organizer
  第４０回頭頸部癌学会
- Place of Presentation
  ソニックシティ（埼玉県さいたま市）
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] 咽頭扁平上皮癌におけるCox2-inhibitionとE-cadherin発現制御に関する検討2016
- Author(s)
  渡部佳弘，今西順久，小澤宏之，藤井良一，羽生　昇，佐藤陽一郎，関水真理子，伊藤文展，猪狩雄一，斎藤　真，小川　郁
- Organizer
  第4回南関東頭頸部腫瘍懇話会
- Place of Presentation
  ベルサール新宿グランド（東京都新宿区）
- Year and Date
  2016-03-31
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 咽頭扁平上皮癌におけるCox2-inhibitionとE-cadherin発現制御に関する検討2016
- Author(s)
  渡部佳弘
- Organizer
  第４０回日本頭頸部癌学会
- Place of Presentation
  さいたまソニックシティ（埼玉県さいたま市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15K20225
[Presentation] 頭頸部癌における同所移植転移モデルの確立とHIF１αの転移への関与について2015
- Author(s)
  小澤宏之　伊藤文展　渡部佳弘　関水真理子　冨田俊樹　小川郁
- Organizer
  第39頭頸部癌学会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-06-04
- Data Source
  KAKENHI-PROJECT-26462623
[Presentation] 頭頸部扁平上皮癌における選択的Cox-2阻害によるE-cadherin発現回復とEMT（epithelial-to-mesenchymal transition）の臨床的関連2015
- Author(s)
  藤井良一，今西順久，柴田克志，酒井伸也，坂本耕二，重冨征爾，羽生　昇，大塚邦憲，佐藤陽一郎，渡部佳弘，小澤宏之，冨田俊樹，亀山香織，藤井正人，小川　郁
- Organizer
  2015年度慶應義塾大学医学部耳鼻咽喉科学教室総会講演会
- Place of Presentation
  ベルサール新宿グランド（東京都新宿区）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における選択的Cox-2阻害によるE-cadherin発現回復とEMT (epithelial-to-mesenchymal transition)の臨床的関連2015
- Author(s)
  藤井良一，今西順久，柴田克志，酒井伸也，坂本耕二，重冨征爾，羽生　昇，大塚邦憲，佐藤陽一郎，渡部佳弘，小澤宏之，冨田俊樹，亀山香織，藤井正人，小川　郁
- Organizer
  第21回　東大・慶應ジョイントカンファレンス
- Place of Presentation
  東京
- Year and Date
  2015-02-12
- Data Source
  KAKENHI-PROJECT-25462692
[Presentation] 頭頸部扁平上皮癌における癌幹細胞様細胞マーカーの発現とその臨床的意義に関する検討2013
- Author(s)
  羽生昇, 今西順久, 坂本耕二, 大塚邦憲, 佐藤陽一郎, 渡部佳弘, 小川郁, 徳丸裕, 藤井正人
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-24791806
[Presentation] 頭頸部扁平上皮癌におけるがん幹細胞様細胞の存在とmarker の発現に関する検討2013
- Author(s)
  羽生昇, 今西順久, 徳丸裕, 冨田俊樹, 坂本耕二, 重冨征爾, 佐藤陽一郎, 渡部佳弘, 藤井正人, 小川郁
- Organizer
  第114回日本耳鼻咽喉科学会総会
- Place of Presentation
  札幌
- Year and Date
  2013-05-18
- Data Source
  KAKENHI-PROJECT-24791806

1. IMANISHI Yorihisa (80255538)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. SATO Yoichiro (40624440)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. FUJII Ryoichi (30348742)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. SHIGETOMI Seiji (30365366)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. HABU Noboru (60365369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. OOTSUKA Kuninori (40465026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. SAKAMOTO Koji (80338136)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. OZAWA Hiroyuki (30327621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
9. SEKIMIZU Mariko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IKARI Yuichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAITO Shin

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Chung Christine

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Watanabe Yoshihiro 渡部 佳弘

WATANABE YOSHIHIRO 渡部 佳弘

WATANABE Yoshihiro 渡部 佳弘

Research Projects

Research Products

Co-Researchers

Research to improve the technique and introduce safety of endoscopic laryngopharyngeal surgeryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of COX-2 expression and elucidation of anticancer drug resistance mechanism in head and neck cancersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of HIF1-alpa expression for head and neck cancer metastasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Control of metastasis and cancer stem-like cell property by inducing MET (mesenchymal-epithelial transition) in head and neck cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of head and neck cancer treatment targeting signaling pathway to induce the cancer stem cells and the Epithelial-mesenchymal transition

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study to control metastasis of HNSCC by targeting molecular mechanisms leading to epithelial-mesenchymal transition (EMT)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ oral tongue squamous cell carcinoma2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Restoration of E-cadherin expression by selective Cox-2 inhibition and the clinical relevance of the epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 経口直達的下咽頭喉頭部分切除術における手技的工夫2013

Author(s)

Journal Title

Data Source

[Presentation] The Cox2 and EP2 inhibition suppress EMT and the expression of Cox2 and E-cadherin involved into pharyngeal carcinoma2017

Author(s)

Organizer

Data Source

[Presentation] 咽頭扁平上皮癌におけるCox2及びEP2選択的阻害によるEMT抑制効果とE-cadherinとCox2発現の2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Anti-cancer effects of selective Cox-2 and EP2 inhibition through suppression of EMT and the clinical implications of overexpression of Cox-2 and downregulation of E-cadherin in pharyngeal squamous cell carcinoma2017

Author(s)

Organizer

Data Source

[Presentation] 咽頭扁平上皮癌におけるCox2及びEP2選択的阻害によるEMT抑制効果とE-cadherinとCox2発現の評価2017

Author(s)

Organizer

Data Source

[Presentation] The functional and clinicopathological analysis of hypoxia inducible factor-1α (HIF1-α) in head and neck squamous cell carcinoma.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Watanabe Yoshihiro 渡部佳弘

WATANABE YOSHIHIRO 渡部佳弘

WATANABE Yoshihiro 渡部佳弘

[Journal Article] Expression of Oct3/4 and Nanog in the head and neck squamous carcinoma cells and its clinical implications for delyaed neck metastasis in stageⅠ/Ⅱ　oral tongue squamous cell carcinoma2015