Saka Kanju 坂幹樹

… Alternative Names

SAKA Kanju 坂幹樹

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Researcher Number	30447388
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 技術専門職員
Affiliation (based on the past Project Information) *help	2016 – 2023: 東京大学, 大学院医学系研究科(医学部), 技術専門職員 2012 – 2014: 東京大学, 医学(系)研究科(研究院), 技術専門職員 2013: 東京大学, 医学系研究科 2012 – 2013: 東京大学, 医学(系)研究科(研究院), その他 2010: 東京大学, 大学院・医学系研究科, 技術職員 2007 – 2008: The University of Tokyo, 大学院・医学系研究科, 技術専門職員
Review Section/Research Field	Principal Investigator Legal medicine / Basic Section 58040:Forensics medicine-related Except Principal Investigator Legal medicine / Society medicine, Nursing, and related fields
Keywords	Principal Investigator in silico / QSAR / 予測モデル / 腐敗試料 / 数値モデル / 定量的構造物性相関 / 腐敗血液 / 内部標準物質 / 定量分析 / ノンターゲット薬毒物スクリーニング … More / LC-QTOF-MS / 保持時間予測 / 薬毒物データベース / ノンターゲット薬物スクリーニング / 社会医学 / 法医中毒学 / 致死濃度 / 危険ドラッグ / 血中致死濃度 / 構造物性相関 / 回収率 / 液-液抽出 / 生体試料 / 法医学 / 定量的構造物性（活性）相関 / 薬毒物分析 / 薬物分析 / マトリックス効果 / カルボン酸 / ガスクロマトグラフィー … More Except Principal Investigator 法医中毒学 / 定量法 / 標準化 / Lidocaine / 定量方法 / 腐敗組織 / 内部標準法 / 標準添加法 / QuEChERS法 / LC-MS/MS / GC-MS / NAGINATA / 薬毒物スクリーニング / 心理的ストレス / 心臓性突然死 / 心筋収縮帯 / 虚血再灌流 / 心筋梗塞 / 身体拘束 / 心理ストレス / 心筋虚血 / 心臓突然死 / 不整脈 / ギャップ結合 / コネクシン43 Less

Mathematical model of internal standard selection criteria for accurate quantitative analysisPrincipal Investigator
- Principal Investigator
  
  坂幹樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  The University of Tokyo
Development of a non-target drug screening system using in silico predictionPrincipal Investigator
- Principal Investigator
  
  SAKA Kanju
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58040:Forensics medicine-related
- Research Institution
  The University of Tokyo
Challenging study to establish a standard method for the determination of drugs in special samples containing putrefied tissue
- Principal Investigator
  
  Kudo Keiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Society medicine, Nursing, and related fields
- Research Institution
  Kurume University
  Kyushu University
Development of prediction model of fatal blood concentrations for designer drugsPrincipal Investigator
- Principal Investigator
  
  Saka Kanju
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo
Building of the equation predict an optimal condition for drug analysis in biological samplePrincipal Investigator
- Principal Investigator
  
  SAKA Kanju
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo
Development of a reliable semiquantitative screening method for forensic samples
- Principal Investigator
  
  KUDO KDIKO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Legal medicine
- Research Institution
  Kyushu University
Research on the molecular mechanism underlying sudden cardiac deaths due to toxic substanses, ischemia and emotional stress
- Principal Investigator
  
  YOSHIDA Ken-ichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo
The study of the method for improving sensitivity of gaschromatography by carboxylic acid additionPrincipal Investigator
- Principal Investigator
  
  SAKA Kanju
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  The University of Tokyo

[Book] 薬毒物情報インデックス2014
- Author(s)
  鈴木修、大野曜吉、須崎紳一郎、花尻（木倉）瑠璃、林田眞喜子、工藤恵子、栗崎恵美子、新津ひさえ、寺田賢、梶原正弘、斉藤剛、奈女良昭、福家千昭、石井晃、坂幹樹、他
- Total Pages
  716
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-24590850
[Journal Article] Detection of lisdexamfetamine and its metabolite d-amphetamine in urine and gastric contents collected from a cadaver at forensic autopsy2023
- Author(s)
  Torimitsu Suguru、Saka Kanju、Noritake Kanako、Namera Akira、Makino Yohsuke、Yamaguchi Rutsuko、Iwase Hirotaro
- Journal Title
  
  Forensic Toxicology
  
  Volume: 41 Issue: 2 Pages: 309-317
- DOI
  10.1007/s11419-022-00654-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10604
[Journal Article] Ropinirole involved in a fatal case: blood and urinary concentrations2022
- Author(s)
  Nagasawa Sayaka、Yamaguchi Rutsuko、Saka Kanju、Torimitsu Suguru、Chiba Fumiko、Yajima Daisuke、Inokuchi Go、Motomura Ayumi、Kira Kei、Yamagishi Yoshikazu、Ogra Yasumitsu、Iwase Hirotaro
- Journal Title
  
  Forensic Toxicology
  
  Volume: 40 Issue: 1 Pages: 173-179
- DOI
  10.1007/s11419-021-00593-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679, KAKENHI-PROJECT-19K19380
[Journal Article] Simple and simultaneous quantification of cyanide, ethanol, and 1-propanol in blood by headspace GC-MS/NPD with Deans switch dual detector system2022
- Author(s)
  Saka Kanju、Kudo Keiko、Namera Akira、Fujii Yusuke、Noritake Kanako、Torimitsu Suguru、Makino Yohsuke、Iwase Hirotaro
- Journal Title
  
  Science & Justice
  
  Volume: 62 Issue: 2 Pages: 193-202
- DOI
  10.1016/j.scijus.2022.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679
[Journal Article] Association between sexual activity-related death and non-prescription use of phosphodiesterase type 5 inhibitors2021
- Author(s)
  Nagasawa Sayaka、Saka Kanju、Yamagishi Yoshikazu、Yajima Daisuke、Chiba Fumiko、Yamaguchi Rutsuko、Torimitsu Suguru、Iwase Hirotaro
- Journal Title
  
  Legal Medicine
  
  Volume: 48 Pages: 101815-101815
- DOI
  10.1016/j.legalmed.2020.101815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679, KAKENHI-PROJECT-19K19481
[Journal Article] Effects of putrefaction on the quantitative analyses of diphenhydramine in blood and tissues: model experiments by the routine matrix-matched calibration method and standard addition method with different internal standards2021
- Author(s)
  Kudo Keiko、Saka Kanju、Waters Brian、Hara Kenji、Matsusue Aya、Kashiwagi Masayuki、Kubo Shin-ichi
- Journal Title
  
  Forensic Toxicology
  
  Volume: 39 Issue: 2 Pages: 437-450
- DOI
  10.1007/s11419-021-00580-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679
[Journal Article] 法医剖検診断のための質量分析計（MS）を用いた薬毒物スクリーニングと定量検査－現在の流れと今後の方向性2020
- Author(s)
  工藤恵子、坂幹樹、久保真一
- Journal Title
  
  法医病理
  
  Volume: 26 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679
[Journal Article] 法医剖検診断のための質量分析計 (MS) を用いた薬毒物スクリーニングと定量検査　ー現在の流れと今後の方向性2020
- Author(s)
  工藤恵子、坂幹樹、久保真一
- Journal Title
  
  法医病理
  
  Volume: 26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19819
[Journal Article] A Fatal Case of Poisoning with Fentanyl Transdermal Patches in Japan2019
- Author(s)
  Nara Akina、Yamada Chiho、Saka Kanju、Kodama Takanori、Yoshida Masaki、Iwahara Kaori、Takagi Tetsuya
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: 64 Issue: 6 Pages: 1936-1942
- DOI
  10.1111/1556-4029.14127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679
[Journal Article] Olanzapine‐Induced Fatal Ketoacidosis with Pneumomediastinum and Subcutaneous Emphysema2019
- Author(s)
  Torimitsu Suguru、Makino Yohsuke、Saka Kanju、Fujii Yusuke、Abe Hiroko、Chiba Fumiko、Yamaguchi Rutsuko、Iwase Hirotaro
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: 64 Issue: 3 Pages: 930-933
- DOI
  10.1111/1556-4029.13942
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K10679
[Journal Article] Forensic analysis using ultra-high-performance liquid chromatography-tandem mass spectrometry with solid-phase extraction of α-solanine and α-chaconine in whole blood2019
- Author(s)
  Nara Akina、Saka Kanju、Yamada Chiho、Kodama Takanori、Takagi Tetsuya
- Journal Title
  
  Forensic Toxicology
  
  Volume: 37 Issue: 1 Pages: 197-206
- DOI
  10.1007/s11419-018-0452-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09200
[Journal Article] Fatal intoxication with 1,1-difluoroethane (DFE) due to inhalation of a spray cleaner: analysis by GC-MS2019
- Author(s)
  Torimitsu Suguru、Fujii Yusuke、Saka Kanju、Abe Hiroko、Makino Yohsuke、Chiba Fumiko、Iwase Hirotaro
- Journal Title
  
  Forensic Toxicology
  
  Volume: 37 Issue: 1 Pages: 245-249
- DOI
  10.1007/s11419-018-0435-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09200
[Journal Article] Fatal Poisoning with Both Dichlorvos and Phenthoate2018
- Author(s)
  Nara Akina、Yamada Chiho、Kodama Takanori、Saka Kanju、Takagi Tetsuya
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: 63 Issue: 6 Pages: 1928-1931
- DOI
  10.1111/1556-4029.13781
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09200
[Journal Article] High-Throughput Functional Evaluation of Variants of Unknown Significance inERBB22018
- Author(s)
  Nagano Masaaki、Kohsaka Shinji、Ueno Toshihide、Kojima Shinya、Saka Kanju、Iwase Hirotaro、Kawazu Masahito、Mano Hiroyuki
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 24 Issue: 20 Pages: 5112-5122
- DOI
  10.1158/1078-0432.ccr-18-0991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07250, KAKENHI-PROJECT-16K09200
[Journal Article] Experimental Study on the Postmortem Redistribution of the Substituted Phenethylamine, 25B-NBOMe2017
- Author(s)
  Shintani-Ishida Kaori、Saka Kanju、Nakamura Mami、Yoshida Ken-ichi、Ikegaya Hiroshi
- Journal Title
  
  Journal of Forensic Sciences
  
  Volume: 63 Issue: 2 Pages: 588-591
- DOI
  10.1111/1556-4029.13583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09200, KAKENHI-PROJECT-16K09215
[Journal Article] A case of fatal intoxication due to the new designer drug 25B-NBOMe2015
- Author(s)
  Ken-ichi Yoshida, Kanju Saka, Kaori Shintani-Ishida, Hideyuki Maeda, Makoto Nakajima, Shu-ichi Hara, Masahide Ueno, Katsunori Sasaki, Hirotaro Iwase, Tetsuya Sakamoto
- Journal Title
  
  Forensic Toxicology
  
  Volume: 印刷中 Issue: 2 Pages: 396-401
- DOI
  10.1007/s11419-015-0276-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850, KAKENHI-PROJECT-25293162
[Journal Article] Rapid and simultaneous extraction of acidic and basic drugs from human whole blood for reliable semi-quantitative NAGINATA drug screening by GC-MS2014
- Author(s)
  Kudo K, Usumoto Y, Usui K, Hayashida M, Kurisaki E, Saka K, Tsuji A, Ikeda N
- Journal Title
  
  Forensic Toxicology
  
  Volume: 32 Issue: 1 Pages: 97-104
- DOI
  10.1007/s11419-013-0215-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850, KAKENHI-PROJECT-24659338, KAKENHI-PROJECT-24790637
[Journal Article] MDMA induces cardiac contractile dysfunction through autophagy upregulation and lysosome destabilization in rats2014
- Author(s)
  Shintani-Ishida K, Saka K, Yamaguchi K, Hayashida M, Nagai H, Takemura G, Yoshida K
- Journal Title
  
  Biochimca et Biophysica Acta
  
  Volume: 1842 Issue: 5 Pages: 691-700
- DOI
  10.1016/j.bbadis.2014.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850, KAKENHI-PROJECT-24659334, KAKENHI-PROJECT-25293162
[Journal Article] Sudden death after sustained restraint following self-administration of the designer drug α-pyrrolidinovalerophenone2014
- Author(s)
  Nagai H, Saka K, Nakajima M, Maeda H, Kuroda R, Igarashi A, Tsujimura-Ito T, Nara A, Komori M, Yoshida K
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 172 Issue: 1 Pages: 263-265
- DOI
  10.1016/j.ijcard.2013.12.262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850
[Journal Article] Rapid and simultaneous extraction of acidic and basic drugs from human whole blood for reliable semi-quantitative NAGINATA drug screening by GC-MS2014
- Author(s)
  K. Kudo, Y. Usumoto, K. Usui, M. Hayashida, E. Kurisaki, K. Saka, A. Tsuji, N. Ikeda
- Journal Title
  
  Forensic Toxicol
  
  Volume: 32 Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659338
[Journal Article] Small focal coagulation necrosis in the myocardium of a young methamphetamine user2013
- Author(s)
  Kuroda R, Nakajima M, Nagai H, Maeda H, Kashima J, Saka K, Shintani-Ishida K, Igarashi A, Yoshida K
- Journal Title
  
  International Journal of Cardiology
  
  Volume: 164 Issue: 1 Pages: e5-e6
- DOI
  10.1016/j.ijcard.2012.09.145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850, KAKENHI-PROJECT-25293162
[Journal Article] Relationship between the matrix effect and the physicochemical properties of analytes in gas chromatography2013
- Author(s)
  Saka K, Kudo K, Hayashida M, Kurisaki E, Niitsu H, Terada M, Yamaguchi K, Yoshida K
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 405 Issue: 30 Pages: 9879-9888
- DOI
  10.1007/s00216-013-7433-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850, KAKENHI-PROJECT-24659338
[Journal Article] Relationship between the matrix effect and physicochemical properties of analytes in gas chromatography2013
- Author(s)
  K. Saka, K. Kudo, M. Hayashida, E. Kurisaki, H. Niitsu, M. Terada, K. Yamaguchi, K. Yoshida
- Journal Title
  
  Anal Bioanal Chem
  
  Volume: 405 Pages: 9879-9888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659338
[Journal Article] An autopsy case of acute carbon monoxide poisoning with fatal hypnotic drugs in the blood2013
- Author(s)
  Fujii Y, Funakoshi T, Uchida K, Watanabe M, Saka K, Uemura K
- Journal Title
  
  International Medical Journal
  
  Volume: 20 Pages: 587-588
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850
[Journal Article] Acute fatal poisoning with Tolfenpyrad2013
- Author(s)
  Hikiji W, Yamaguchi K, Saka K, Hayashida M, Ohno Y, Fukunaga T
- Journal Title
  
  Journal of Forensic and Legal Medicine
  
  Volume: 20 Issue: 8 Pages: 962-964
- DOI
  10.1016/j.jflm.2013.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850
[Journal Article] Analysis of tolfenpyrad and its metabolites in plasma in a tolfenpyrad poisoning case2012
- Author(s)
  Yamaguchi K, Hikiji W, Takino M, Saka K, Hayashida M, Fukunaga T, Ohno Y
- Journal Title
  
  Journal of Analytical Toxicology
  
  Volume: 36 Issue: 7 Pages: 529-537
- DOI
  10.1093/jat/bks060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590850
[Journal Article] Identification of active ingredients in dietary supplements using non non-destructive mass spectrometry and liquid chromatography-mass spectrometry.2009
- Author(s)
  Saka K, Yoshida K(6名中6番目)
- Journal Title
  
  Forensic Sci Int. 191
  
  Pages: 5-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390193
[Journal Article] Determination of amobarbital and phenobarbital in serum by gas chromatography-mass spectrometry with addition of formic acid to the solvent2008
- Author(s)
  Kanju Saka
- Journal Title
  
  Journal of Chromatography B 869
  
  Pages: 9-15
- NAID
  10028001848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590669
[Journal Article] Biochemical blood markers and sampling sites in forensic autopsy.2008
- Author(s)
  Uemura K, Shintani-Ishida K, Saka K, Nakajima M, Ikegaya H, Kikuchi Y, Yoshida K
- Journal Title
  
  J Forensic Leg Med 15
  
  Pages: 312-317
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390193
[Journal Article] Determination of amobarbital and phenobarbital in serum by gas chroma tography-mass spectrometry with addition of formic acid to the solvent2008
- Author(s)
  Saka K, Uemura K, Shintani-Ishida K, Yoshida K
- Journal Title
  
  J Chromatogr B. 869
  
  Pages: 9-15
- NAID
  10028001848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390193
[Journal Article] A death due to perirenal hematoma complicating extracorporeal shockwave lithotripsy.2008
- Author(s)
  Uemura K, Takahashi S, Shintani-shida K, Nakajima M, Saka K, Yoshida K
- Journal Title
  
  J Forensic Sci. 53
  
  Pages: 469-471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390193
[Journal Article] Determination of amobarbitaland phenobarbital in serum by gaschromatography-mass spectrometry withaddition of formic acid to the solvent2008
- Author(s)
  Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
- Journal Title
  
  J Chromatogr B. 869
  
  Pages: 9-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590669
[Journal Article] Acetic acid improves thesensitivity of theophylline analysis by gaschromatography-mass spectrometry2007
- Author(s)
  Saka K, Uemura K, Shintani-Ishida K, Yoshida K.
- Journal Title
  
  J Chromatogr B. 846
  
  Pages: 240-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590669
[Journal Article] Autopsy report on pseudo-Bartter syndrome with renal calcification induced by diuretics and diet pills.
- Author(s)
  Unuma K, Tojo A ; Harada K, Saka K ; Nakajima M ; Ishii T ; Fujita T, Yoshida K.
- Journal Title
  
  BMJ Report. (on-line journal)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] Development of criteria for selecting internal standards for quantifying flunitrazepam and 7-aminoflunitrazepam in putrefied blood samples2023
- Author(s)
  Saka Kanju、Noritake Kanako、Makino Yohsuke、Torimitsu Suguru、Yamaguchi Rutsuko、Chiba Fumiko、Tsuneya Shigeki、Iwase Hirotaro
- Organizer
  The 60th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT2023)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10604
[Presentation] トラマドールとベンラファキシン代謝物について2023
- Author(s)
  坂幹樹
- Organizer
  第11回法医中毒研究会勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-22K10604
[Presentation] Simple and simultaneous quantification of cyanide, ethanol, and 1-propanol in blood by headspace GC-MS/NPD with a Deans switch2022
- Author(s)
  Kanju Saka, Keiko Kudo, Akira Namera, Yusuke Fujii, Kanako Noritake, Suguru Torimitsu, Yohsuke Makino, Hirotaro Iwase
- Organizer
  The 59th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K10604
[Presentation] LC-QTOF-MS + in silico 予測を用いた血中薬毒物ノンターゲットスクリーニング法の構築2021
- Author(s)
  坂　幹樹
- Organizer
  薬毒物分析Webinar～薬毒物分析に悩めるあなたへ～
- Invited
- Data Source
  KAKENHI-PROJECT-19K10679
[Presentation] 状況に応じた定量分析-レボメプロマジン-2021
- Author(s)
  坂幹樹
- Organizer
  第10回法医中毒研究会セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K10679
[Presentation] Development of a non-target drug screening system in blood using LC-QTOF-MS with in silico approachs2019
- Author(s)
  Saka K, Nakazono Y, Kudo K, Imoto E, Iida T, Minohata T, Furuta K, Fujii Y, Makino Y, Iwase H
- Organizer
  The 57th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10679
[Presentation] 腐敗組織を含む特殊試料中薬物の標準的定量法の確立（第1報）2019
- Author(s)
  工藤恵子、坂幹樹、副島美貴子、池田典昭、久保真一、神田芳郎
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] Development of a non-target drug screening system in blood using LC-QTOF-MS with in silico approachs.2019
- Author(s)
  Saka K, Nakazono Y, Kudo K, Imoto E, Iida T, Minohata T, Furuta K, Fujii Y, Makino Y, Iwase H
- Organizer
  The 57th Annual Meeting of the International Association of Forensic Toxicologists (TIAFT2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] 検出器スイッチングを用いたシアン化物、アルコール類、その他の揮発性化合物のヘッドスペースGCによる一斉分析2019
- Author(s)
  坂幹樹、工藤恵子、奈女良昭、太田瀬亮、滝埜昌彦、藤井祐介、槇野陽介、岩瀬博太郎
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] 検出器スイッチングを用いたシアン化物、アルコール類、その他の揮発性化合物のヘッドスペースGCによる一斉分析2019
- Author(s)
  坂幹樹, 工藤恵子, 奈女良昭, 太田瀬亮, 滝埜昌彦, 藤井祐介, 槇野陽介, 岩瀬博太郎
- Organizer
  日本法中毒学会第38年会
- Data Source
  KAKENHI-PROJECT-19K10679
[Presentation] 法医中毒学へのin silicoモデル活用事例：マトリックス効果予測・保持時間予測・薬物血中致死濃度予測2018
- Author(s)
  坂幹樹
- Organizer
  情報計算化学生物学会（CBI学会）
- Invited
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] 薬物の血中致死濃度予測モデルの検討2018
- Author(s)
  坂幹樹, 工藤恵子, 槇野陽介，池田典昭，岩瀬博太郎
- Organizer
  日本法中毒学会第37年会
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] A state-of-the-art retention time prediction model for non-target drug screening2018
- Author(s)
  Saka K, Nakazono Y, Kudo K, Minohata T, Hirano I, Furuta K, Fujii Y, Makino Y, Ikeda N, Iwase H
- Organizer
  24th Congress of the International Academy of Legal Medicine (IALM)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] A state-of the-art retention time prediction model for non-target drug screening.2018
- Author(s)
  Saka K, Nakazono Y, Kudo K, Minohata T, Hirano I, Furuta K, Fujii Y, Makino Y, Ikeda N, Iwase H,
- Organizer
  24th Congress of the International Academy of Legal Medicine (IALM)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] In silico modeling to predict fatal blood concentrations of drugs (preliminary study)2018
- Author(s)
  Saka K, Kudo K, Makino Y, Ikeda N, Iwase H
- Organizer
  56TH Annual meeting of the international association of forensic toxicologists (TIAFT) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] In silico modeling to predict fatal blood concentrations of new drugs2018
- Author(s)
  Saka K, Kudo K, Makino Y, Ikeda N, Iwase H
- Organizer
  The 56th annual meeting of the International Association of Forensic Toxicologists,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] 薬物の血中致死濃度予測モデルの検討2018
- Author(s)
  坂　幹樹、工藤恵子、槇野陽介、池田典昭、岩瀬博太郎
- Organizer
  日本法中毒学会第37年会
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] In silicoを用いたノンターゲット血中薬物スクリーニング法の構築（第2報）.2017
- Author(s)
  坂　幹樹，中園裕紀子, 工藤恵子, 箕畑俊和, 兼城昌敏，平野一郎，古田一匡，藤井祐介，槇野陽介，池田典昭，岩瀬博太郎．
- Organizer
  日本法中毒学会第36年会. 講演要旨集. 2017; p81, 東京.
- Data Source
  KAKENHI-PROJECT-17K19819
[Presentation] In silicoを用いたノンターゲット血中薬物スクリーニング法の構築（第2報）2017
- Author(s)
  坂幹樹, 中園裕紀子, 工藤恵子, 箕畑俊和, 兼城昌敏, 平野一郎, 古田一匡, 藤井祐介, 槇野陽介，池田典昭，岩瀬博太郎
- Organizer
  日本法中毒学会第36年会
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] ACD/MS Structure ID Suite, ACD/ChromGeniusを用いたLC/MS血中薬物スクリーニング法の構築2016
- Author(s)
  坂　幹樹
- Organizer
  ACD/Labs日本ユーザー会2016
- Place of Presentation
  品川インターシティC棟富士通マーケティング本社（東京都港区）
- Year and Date
  2016-10-18
- Invited
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] In silicoによるLC/MSを用いた血中薬物スクリーニング法の構築2016
- Author(s)
  坂　幹樹
- Organizer
  日本法中毒学会第35年会
- Place of Presentation
  大阪産業創造館（大阪府大阪市）
- Year and Date
  2016-07-01
- Data Source
  KAKENHI-PROJECT-16K09200
[Presentation] 危険ドラッグ25B-NBOMe中毒例における血中濃度の経時測定2015
- Author(s)
  坂　幹樹
- Organizer
  第99次日本法医学会学術全国集会
- Place of Presentation
  高知市文化プラザ　かるぽーと（高知県高知市）
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-24590850
[Presentation] Rapid and simultaneous extraction of acidic and basic drugs using modified QuEChERS method and protein–lipid removal filter cartridge2014
- Author(s)
  K. Kudo, Y. Usumoto, K. Usui, M. Hayashida, E. Kurisaki, K. Saka, A. Tsuji, N. Ikeda
- Organizer
  9^<th> International Symposium on Advances in Legal Medicine
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-24659338
[Presentation] Rapid and simultaneous extraction of acidic and basic drugs using modified QuEChERS method and protein–lipid removal filter cartridge2014
- Author(s)
  Kudo K, Usumoto Y, Usui K, Hayashida M, Kurisaki E • Saka K, Tsuji A, Ikeda N
- Organizer
  9th International Symposium on Advances in Legal Medicine
- Place of Presentation
  Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-24659338
[Presentation] MDMA及びその活性代謝物(DHMA, DHA)のLC-MS/MS同時定量のための前処理法の検討2013
- Author(s)
  坂幹樹,新谷香,山口晃志,林田眞喜子,大野曜吉,吉田謙一
- Organizer
  第82回日本法医学会学術関東地方会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24659338
[Presentation] タイから輸入された痩せ薬主成分分析2008
- Author(s)
  坂幹樹、鵜沼香奈、小沼純貴、浅井重博、新谷香、中嶋信、笠原麻美、吉田謙一
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京大学鉄門記念講堂(東京都文京区)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] タイのダイエット薬を服用中であった女性の突然死の1剖検例2008
- Author(s)
  鵜沼香奈、原田一樹、坂幹樹、中嶋信、高橋香、高橋麻衣子、藤乗嗣泰、吉田謙一
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京大学鉄門記念講堂(東京都文京区)
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] タイから輸入された痩せ薬の主成分分析2008
- Author(s)
  坂幹樹,鵜沼香奈,小沼純貴,浅井重博,新谷香,中嶋信,笠原麻美,吉田謙一
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京大学鉄門記念講堂
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] タイから輸入された痩せ薬の主成分分析2008
- Author(s)
  坂幹樹
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京都文京区東京大学医学部教育研究棟鉄門記念講堂
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590669
[Presentation] Gap junctionsは心筋虚血再灌流時におけるcontraction bandの細胞間伝播に関与する2008
- Author(s)
  新谷香,鵜沼香奈,高橋香,坂幹樹,吉田謙一
- Organizer
  第92次日本法医学会総会
- Place of Presentation
  長崎ブリッグホール
- Year and Date
  2008-04-24
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] タイのダイエット薬を服用中であった女性の突然死の1剖検例2008
- Author(s)
  鵜沼香奈,原田一樹,坂幹樹,中嶋信,高橋香,高橋麻衣子,藤乗嗣泰,吉田謙一
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京大学鉄門記念講堂
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] Gap Junctions は心筋虚血再灌流時におけるcontraction bandの細胞間伝播に関与する2008
- Author(s)
  新谷香、鵜沼香奈、高橋香、坂幹樹、吉田謙一
- Organizer
  第92次日本法医学会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市)
- Year and Date
  2008-04-24
- Data Source
  KAKENHI-PROJECT-20390193
[Presentation] タイから輸入された痩せ薬の主成分分析2008
- Author(s)
  坂幹樹
- Organizer
  第77回日本法医学会関東地方会
- Place of Presentation
  東京都文京区東京大学医学部教育研究棟鉄門記念講堂
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590669
[Presentation] MDMA及びその活性代謝物（DHMA, DHA）のLC-MS/MS同時定量のための前処理法の検討
- Author(s)
  坂幹樹, 新谷香, 山口晃志, 林田眞喜子, 大野曜吉, 吉田謙一
- Organizer
  第82回日本法医学会学術関東地方会
- Place of Presentation
  横浜市　はまぎんホールヴィアマーレ
- Data Source
  KAKENHI-PROJECT-24590850

1. YOSHIDA KEN-ICHI (40166947)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. SHINTANI Kaori (50345047)

# of Collaborated Projects: 4 results

# of Collaborated Products: 13 results
3. UEMURA KOICHI (30244586)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. KUDO KDIKO (10186405)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
5. UEYAMA Takashi (50264875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Hiroko (00053299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HARADA Kazuki (00253146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. HAYASHIDA Makiko (60164977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 辻彰子 (10171993)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 池田典昭 (60176097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. IWASE hirotaro

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
12. 林田真喜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
13. 上野敏秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saka Kanju 坂 幹樹

SAKA Kanju 坂 幹樹

Research Projects

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Co-Researchers

Mathematical model of internal standard selection criteria for accurate quantitative analysisPrincipal Investigator

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Development of a non-target drug screening system using in silico predictionPrincipal Investigator

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Challenging study to establish a standard method for the determination of drugs in special samples containing putrefied tissue

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Development of prediction model of fatal blood concentrations for designer drugsPrincipal Investigator

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Building of the equation predict an optimal condition for drug analysis in biological samplePrincipal Investigator

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Development of a reliable semiquantitative screening method for forensic samples

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Research on the molecular mechanism underlying sudden cardiac deaths due to toxic substanses, ischemia and emotional stress

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The study of the method for improving sensitivity of gaschromatography by carboxylic acid additionPrincipal Investigator

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[Book] 薬毒物情報インデックス2014

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[Journal Article] Detection of lisdexamfetamine and its metabolite d-amphetamine in urine and gastric contents collected from a cadaver at forensic autopsy2023

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[Journal Article] Ropinirole involved in a fatal case: blood and urinary concentrations2022

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[Journal Article] Simple and simultaneous quantification of cyanide, ethanol, and 1-propanol in blood by headspace GC-MS/NPD with Deans switch dual detector system2022

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[Journal Article] Association between sexual activity-related death and non-prescription use of phosphodiesterase type 5 inhibitors2021

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[Journal Article] Effects of putrefaction on the quantitative analyses of diphenhydramine in blood and tissues: model experiments by the routine matrix-matched calibration method and standard addition method with different internal standards2021

Author(s)

Saka Kanju 坂幹樹

SAKA Kanju 坂幹樹

[Journal Article] 法医剖検診断のための質量分析計 (MS) を用いた薬毒物スクリーニングと定量検査　ー現在の流れと今後の方向性2020