OHTA Rieko 太田里永子

Researcher Number	30452460
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2021: 名古屋市立大学, 医薬学総合研究院(医学), 研究員 2014 – 2019: 愛知県がんセンター(研究所), その他部局等, 研究員 2018: 名古屋市立大学, 大学院医学研究科, 研究員 2014 – 2017: 愛知県がんセンター(研究所), 腫瘍免疫学部, 研究員 2012 – 2013: 名古屋市立大学, 医学(系)研究科(研究院), 助教 2011: 名古屋市立大学, 大学院・医学研究科, 助教 2010: Nagoya City University, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 抗体 / 腫瘍免疫 / MUC1 / 補体 / 口腔癌 / TCR / T細胞受容体 / 膜侵襲複合体 / がん特異的TCR / 親和性の成熟 … More / Ｔ細胞受容体 / 細胞障害性T細胞 / アジュバント / ワクチン … More Except Principal Investigator 口腔癌 / 頭頸部癌 / 制御性T細胞 / 補体 / C5a / 歯周病 / 腹膜透析 Less

Affinity maturation of cancer-specific TCRs by in vitro cell display methods and their application to drug discovery.Principal Investigator
- Principal Investigator
  
  OHTA RIEKO
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya City University
Elucidation of cancer growth mechanisms by C5a-C5aR axis
- Principal Investigator
  
  Imai Masaki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagoya City University
The development of targeted molecular therapy with RAGE on the Oral Squamous Cell CarcinomaPrincipal Investigator
- Principal Investigator
  
  Ohta Rieko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Aichi Cancer Center Research Institute
Influence of periodontal disease-causing bacteria infection on peritoneal dialysis
- Principal Investigator
  
  IMAI Masaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagoya City University
Development of novel vaccine for oral cancer utilizing endogenous adjuvantPrincipal Investigator
- Principal Investigator
  
  OHTA Rieko
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Nagoya City University

All 2020 2019 2018 2017 2016 2015 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Improving TCR affinity on 293T cells2019
- Author(s)
  Ohta Rieko、Demachi-Okamura Ayako、Akatsuka Yoshiki、Fujiwara Hiroshi、Kuzushima Kiyotaka
- Journal Title
  
  Journal of Immunological Methods
  
  Volume: 466 Pages: 1-8
- DOI
  10.1016/j.jim.2018.11.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07285, KAKENHI-PROJECT-18K08341, KAKENHI-PROJECT-18K08361, KAKENHI-PROJECT-16K07192, KAKENHI-PROJECT-17K07238
[Journal Article] Interleukin-17A-Producing T Lymphocytes in Chronic Active Epstein-Barr Virus Infection.2013
- Author(s)
  Ohta R
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 57 Issue: 2 Pages: 139-144
- DOI
  10.1111/1348-0421.12010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659081, KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23792148, KAKENHI-PROJECT-24659493, KAKENHI-PROJECT-24791055
[Journal Article] Human herpesvirus 6-associated encephalopathy in a child with dravet syndrome2013
- Author(s)
  Hiraiwa-Sofue A, Ito Y, Ohta R, Kimura H, Okumura A
- Journal Title
  
  Neuropediatrics
  
  Volume: 44 Issue: 03 Pages: 155-158
- DOI
  10.1055/s-0032-1327772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23591518, KAKENHI-PROJECT-23591564
[Journal Article] Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria2012
- Author(s)
  Murakami, Y., N. Inoue, T. Shichishima, R. Ohta, H. Noji, Y. Maeda, J. Nishimura, Y. Kanakura and T. Kinoshita
- Journal Title
  
  Br. J. Haematol
  
  Volume: 156 Issue: 3 Pages: 383-387
- DOI
  10.1111/j.1365-2141.2011.08914.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247018, KAKENHI-PROJECT-21590326, KAKENHI-PROJECT-22390194, KAKENHI-PROJECT-22591044, KAKENHI-PROJECT-22591067, KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23590363
[Journal Article] Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza2011
- Author(s)
  Ohta R, Torii Y, Imai M, Kimura H, Okada N, Ito Y
- Journal Title
  
  Microbiol Immunol
  
  Volume: 55 Issue: 3 Pages: 191-198
- DOI
  10.1111/j.1348-0421.2011.00309.x
- NAID
  10031121459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23792148
[Journal Article] Increased levels of cytokines and high-mobility group box 1 are associated with the development of severe pneumonia, but not acute encephalopathy, in 2009 H1N1 influenza-infected children2011
- Author(s)
  Ito Y, Torii Y, Ohta R, Imai M, Hara S, Kawano Y, et al
- Journal Title
  
  Cytokine
  
  Volume: 56 Issue: 2 Pages: 180-187
- DOI
  10.1016/j.cyto.2011.07.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791813, KAKENHI-PROJECT-23591564, KAKENHI-PROJECT-23792148
[Presentation] 新規活性型カルボキシペプチダーゼRの一次構造予測2020
- Author(s)
  河村剛至、太田里永子、山本博之、今井優樹、安野伸浩
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K07285
[Presentation] Expression of complement anaphylatoxin receptor in the various subsets of dendritic cells2019
- Author(s)
  Masaki Imai, Rieko Ohta, Sayuri Yamazaki
- Organizer
  第48回　日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-17K11679
[Presentation] Expression of complement anaphylatoxin receptor in the various subsets of dendritic cells2019
- Author(s)
  Masaki Imai, Rieko Ohta, Sayuri Yamazaki
- Organizer
  第４８回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K07285
[Presentation] ヒト培養細胞を用いたTCR親和性成熟システムの樹立2018
- Author(s)
  太田里永子、岡村文子、赤塚美樹、葛島清隆
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07285
[Presentation] ミエロイド系細胞における補体アナフィラトキシン受容体の発現解析。2018
- Author(s)
  今井優樹、辻村幸平、太田里永子、山崎小百合
- Organizer
  第28回日本樹状細胞研究会
- Data Source
  KAKENHI-PROJECT-17K11679
[Presentation] 補体活性化による腫瘍の分子標的治療薬の開発2017
- Author(s)
  太田里永子、葛島清隆、藤田禎三、岡田秀親、今井優樹
- Organizer
  第53回日本補体学会
- Data Source
  KAKENHI-PROJECT-17K11679
[Presentation] 補体活性化による腫瘍の分子標的治療薬の開発2017
- Author(s)
  太田里永子, 葛島清隆, 藤田禎三, 岡田秀親, 今井優樹
- Organizer
  第54回補体学会学術集会
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] The complement anaphylatoxin C5adesArg still induce the acute inflammatory response.2016
- Author(s)
  Imai M, Odanaka M, Takayama S, Ohta R, Yamazaki S
- Organizer
  The XXVI International Complement Workshop
- Place of Presentation
  Hotel Nikko Kanazawa（金沢市）
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] The complement anaphylatoxin C5adesArg still induce the acute inflammatory response.2016
- Author(s)
  Imai M, Odanaka M, Takayama S, Ohta R, Yamazaki S
- Organizer
  The Cold Spring Harbor Asia conference on Frontiers of Immunology in Health & Disease
- Place of Presentation
  Awaji Yumebutai Conference Center（淡路市）
- Year and Date
  2016-10-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] C5adesArg still induce the acute inflammatory response.2016
- Author(s)
  Imai M, Odanaka M, Takayama S, Ohta R, Yamazaki S.
- Organizer
  The XXVI International Complement Workshop
- Place of Presentation
  ホテル日航金沢（石川県・金沢市）
- Year and Date
  2016-09-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] 好中球エラスターゼによる新規カルボキシペプチダーゼRの生成2016
- Author(s)
  河村剛至, 太田里永子, 山本博之, 今井優樹, 松浦凌太, 松山悟, 佐古兼一,羽二生久夫, 岡田秀親, 松田佳和
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜他(横浜市)
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] Enhancement of Complement-Dependent Mechanisms of Tumor Cell Lysis by Targeted Bispecific Antibodies2016
- Author(s)
  Ohta R, Imai M, Kuwahara K, Fujita T, Okada H, Kuzushima K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] C5adesArg still induce the acute inflammatory response.2016
- Author(s)
  Imai M, Odanaka M, Takayama S, Ohta R, Yamazaki S.
- Organizer
  The Cold Spring Harbor Asia conference on Frontiers of Immunology in Health & Disease
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県・淡路市）
- Year and Date
  2016-10-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] Differential roles of complement anaphylatoxin C5a and C5adesArg.2015
- Author(s)
  Takayama S, Odanaka M, Ohta R, Imai M, Yamazaki S
- Organizer
  第44回日本免疫学会総会・学術集会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] Differential roles of complement anaphylatoxin C5a and C5adesArg2015
- Author(s)
  Takayama shoryu, Odanaka mizuyu, Ohta Rieko, Imai Masaki, Yamazaki Sayuri
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] Analysis of C5a receptor expression on the various subsets of dendritic cells.2015
- Author(s)
  Tsujimura K, Ohta R, Imai M, Yamazaki S.
- Organizer
  14th International Workshop on Langerhans Cells
- Place of Presentation
  Kyoto International Community House (Kyoto)
- Year and Date
  2015-11-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] Analysis of C5a receptor expression on the various subsets of dendritic cells2015
- Author(s)
  Kohei Tsujimura , Rieko Ohta , Masaki Imai, Sayuri Yamazaki
- Organizer
  LC2015 14th International Workshop on Langerhans Cells
- Place of Presentation
  kyoto international community house (京都市）
- Year and Date
  2015-11-05
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] 好中球エラスターゼにより活性化する新規カルボキシペプチダーゼRの解析2015
- Author(s)
  河村剛至, 太田里永子, 今井優樹, 大澤真以, 塩見友祐, 羽二生久夫, 岡田秀親, 岡田則子, 松田佳和
- Organizer
  第５２回日本補体学会学術集会
- Place of Presentation
  名古屋大学医学部付属病院中央診療棟３階講堂（名古屋市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] C5a第２レセプターC5L2の発現解析2015
- Author(s)
  辻村幸平, 太田里永子, 今井優樹, 山崎小百合
- Organizer
  第５２回日本補体学会学術集会
- Place of Presentation
  名古屋大学医学部付属病院中央診療棟３階講堂（名古屋市）
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] 好中球エラスターゼにより活性化する新規カルボキシペプチダーゼＲの解析2015
- Author(s)
  河村剛至、太田里永子、今井優樹、大澤真以、今井由美、塩見友祐、賀来美和子、佐古兼一、羽二生久夫、岡田秀親、岡田則子、松田佳和
- Organizer
  第52回日本補体学会
- Place of Presentation
  名古屋大学医学部　(名古屋)
- Year and Date
  2015-08-21
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] ヒトにおける MUC1-C3d ワクチンのアジュバント効果の解析2013
- Author(s)
  太田里永子, 神田輝, 安藤史代, 今井優樹
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  国立大学法人旭川医科大学(北海道)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Enhancement of anti-tumor immunity by MUC1-C3d fusion protein2013
- Author(s)
  Rieko Ohta, Fumiyo Ando and Masaki Imai
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] ヒトにおける MUC1-C3d ワクチンのアジュバント効果の解析2013
- Author(s)
  太田里永子, 神田輝, 安藤史代, 今井優樹
- Organizer
  第50回補体シンポジウム
- Place of Presentation
  国立大学法人旭川医科大学（北海道）
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Enhancement of anti-tumor immunity by MUC1-C3d fusion protein2013
- Author(s)
  Ohta R, Ando F and Imai M
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  日幕張メッセ(千葉県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Enhancing antibody immunotherapy by orally administered herbal medicine Juzen-taiho-to2012
- Author(s)
  Imai M, Ohta R and Okada N
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] 口腔癌に対する抗MUC1 モノクローナル抗体の抗腫瘍活性と補体制御膜因子の影響2012
- Author(s)
  今井優樹, 太田里永子, 岡田則子
- Organizer
  第49回補体シンポジウム
- Place of Presentation
  大阪府立成人病センター(大阪府)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Enhancing antibody immunotherapy by orally administered herbal medicine Juzen-taiho-to.2012
- Author(s)
  Imai, M. Ohta, R. Okada, N.
- Organizer
  第４１回日本免疫学会学術集会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza2011
- Author(s)
  Imai M, Ohta R, Okada N
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] 発作性夜間血色素尿症をはじめとするGPI欠損症について2011
- Author(s)
  村上良子, 井上徳光, 七島勉, 太田里永子, 野地秀義, 前田裕輔, 西村純一, 木下タロウ
- Organizer
  第48回補体シンポジウム
- Place of Presentation
  名古屋市立大学(愛知県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] H1N1 インフルエンザの重症化における補体アナフィラトキシン及びHMGB1の関与2011
- Author(s)
  太田里永子, 伊藤嘉規, 鳥居ゆか, 木村宏, 岡田則子, 今井優樹
- Organizer
  第48回補体シンポジウム
- Place of Presentation
  名古屋市立大学医学部(愛知県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] H1N1インフルエンザの重症化における補体アナフィラトキシン及びHMGB1の関与2011
- Author(s)
  太田里永子, 伊藤嘉規, 鳥居ゆか, 木村宏, 岡田則子, 今井優樹
- Organizer
  第48回補体シンポジウム
- Place of Presentation
  名古屋市立大学(愛知県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza2011
- Author(s)
  Imai, M., Ohta, R., Okada, N.
- Organizer
  日本免疫学会総会・学術集会
- Place of Presentation
  幕張メッセ(千葉県)
- Data Source
  KAKENHI-PROJECT-22791813
[Presentation] 線溶抑制を起こさずに炎症を抑制する変異型proCPR作製の試み
- Author(s)
  河村剛至、太田里永子、今井優樹、大澤真以、今井由美、塩見友祐、賀来美和子、佐古兼一、羽二生久夫、松田佳和
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他(神戸市)
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] The production of a recombinant bispecific monoclonal antibody against both the complement inhibitor CD59 and the tumor-associated antigen MUC1
- Author(s)
  Ohta R, Imai M
- Organizer
  第43回日本免疫学会総会・学術集会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] 線溶抑制を起こさずに炎症を抑制する変異型proCPR作製の試み
- Author(s)
  河村剛至,太田里永子,今井優樹,大澤真以,今井由美,羽二生久夫,松田佳和.
- Organizer
  日本薬学会第１３５年会
- Place of Presentation
  神戸学院大学（神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] 好中球エラスターゼによるプロカルボキシペプチダーゼＲ活性化機構の解析
- Author(s)
  河村剛至,大澤真以,今井由美,松田佳和,太田里永子,今井優樹,羽二生久夫,岡田則子,岡田秀親
- Organizer
  第51回補体シンポジウム
- Place of Presentation
  神戸常盤大学(神戸市)
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-26462848
[Presentation] 好中球エラスターゼによるプロカルボキシペプチダーゼＲ活性化機構の解析
- Author(s)
  河村剛至、大澤真以、今井由美、松田佳和、太田里永子、今井優樹、羽二生久夫、岡田則子、岡田秀親
- Organizer
  第51回補体シンポジウム
- Place of Presentation
  神戸常盤大学　(神戸市)
- Year and Date
  2014-08-22 – 2014-08-23
- Data Source
  KAKENHI-PROJECT-26462849
[Presentation] The production of a recombinant bispecific monoclonal antibody against both the complement inhibitor CD59 and the tumor-associated antigen MUC1.
- Author(s)
  Ohta R and Imai M.
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-26462848

1. IMAI Masaki (30440936)

# of Collaborated Projects: 4 results

# of Collaborated Products: 25 results
2. 山崎小百合 (70567255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 葛島清隆 (30311442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 岡村文子 (10546948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MIZUNO Masashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MURAKAMI Yoshiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 前田裕輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 木下タロウ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OHTA Rieko 太田 里永子

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Affinity maturation of cancer-specific TCRs by in vitro cell display methods and their application to drug discovery.Principal Investigator

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Elucidation of cancer growth mechanisms by C5a-C5aR axis

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The development of targeted molecular therapy with RAGE on the Oral Squamous Cell CarcinomaPrincipal Investigator

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Influence of periodontal disease-causing bacteria infection on peritoneal dialysis

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Development of novel vaccine for oral cancer utilizing endogenous adjuvantPrincipal Investigator

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[Journal Article] Improving TCR affinity on 293T cells2019

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[Journal Article] Interleukin-17A-Producing T Lymphocytes in Chronic Active Epstein-Barr Virus Infection.2013

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[Journal Article] Human herpesvirus 6-associated encephalopathy in a child with dravet syndrome2013

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[Journal Article] Deregulated expression of HMGA2 is implicated in clonal expansion of PIGA deficient cells in paroxysmal nocturnal haemoglobinuria2012

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[Journal Article] Serum concentrations of complement anaphylatoxins and proinflammatory mediators in patients with 2009 H1N1 influenza2011

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[Journal Article] Increased levels of cytokines and high-mobility group box 1 are associated with the development of severe pneumonia, but not acute encephalopathy, in 2009 H1N1 influenza-infected children2011

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[Presentation] 新規活性型カルボキシペプチダーゼRの一次構造予測2020

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[Presentation] Expression of complement anaphylatoxin receptor in the various subsets of dendritic cells2019

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[Presentation] Expression of complement anaphylatoxin receptor in the various subsets of dendritic cells2019

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[Presentation] ヒト培養細胞を用いたTCR親和性成熟システムの樹立2018

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OHTA Rieko 太田里永子