Takai Hideki 高井英樹

… Alternative Names

TAKAI Hideki 高井英樹

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Researcher Number	30453898
Other IDs
Affiliation (Current)	2023: 日本大学, 松戸歯学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 日本大学, 松戸歯学部, 准教授 2020 – 2021: 日本大学, 松戸歯学部, 准教授 2015 – 2019: 日本大学, 松戸歯学部, 講師 2015: 日本大学, 松戸歯学部, 専任講師 2014: 日本大学, 松戸歯学部, 助教 … More 2012 – 2013: 日本大学, 歯学部, 助教 2010 – 2011: 日本大学, 松戸歯学部, 助教 2008: 日本大学, 松戸歯学部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology Except Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontology / Periodontal dentistry
Keywords	Principal Investigator 転写因子 / 分化誘導 / miRNA / 歯周組織構成細胞 / 歯根膜線維芽細胞 Except Principal Investigator 接合上皮 / 歯周病 / 歯周炎 / 転写調節 / 歯肉上皮細胞 … More / TNF-α / FDC-SP / ODAM / アメロチン / 炎症 / 歯周組織再生 / 骨シアロタンパク質 / 転写因子 / 遺伝子発現 / 骨芽細胞 / 石灰化 / 遺伝子プロモーター / 診断マーカー / 唾液 / エクソソーム / 歯周病治療 / IKKβ / miR-200b / マイクロRNA / IL-1β / 予防 / 上皮 / 結合組織 / 歯肉 / miR-223 / IKKα / MKP-5 / IL-6 / IL-1 / 炎症性サイトカイン / miRNA / 歯肉線維芽細胞 / タンパク質発現 / サイトカイン / microRNA / 発現調節 / 細胞外マトリックス / アンドロゲン受容体 / アンドロゲン / ホルモン / 成長因子 Less

Elucidation of the roles of junctional epithelial proteins and salivary exosomes as diagnostic markers for periodontal disease
- Principal Investigator
  
  小方頼昌
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
miRNAを用いた転写因子制御による歯周組織関連細胞の分化誘導Principal Investigator
- Principal Investigator
  
  高井英樹
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
接合上皮発現タンパク質の発現制御による歯周病治療戦略
- Principal Investigator
  
  小方頼昌
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
Induction of differentiation of periodontal tissue constituent cells by regulating expression of miRNAPrincipal Investigator
- Principal Investigator
  
  TAKAI Hideki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Nihon University
Strategy for prevention of periodontal disease by controlling protein expressions of junctional epithelium expressed proteins
- Principal Investigator
  
  OGATA Yorimasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Nihon University
Analysis of transcription factors involved in the differentiation induction of periodontal tissue constituent cellsPrincipal Investigator
- Principal Investigator
  
  TAKAI Hideki
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Nihon University
Mechanistic analysis of onset and progress of periodontitis causing microRNA
- Principal Investigator
  
  OGATA Yorimasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Nihon University
Analysis of involved specific transcription factor to differentiation Induction at periodontal tissue component cellsPrincipal Investigator
- Principal Investigator
  
  HIDEKI Takai
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontology
- Research Institution
  Nihon University
Mechanism of transcriptional regulation of extracellular matrix and transcription factors which control periodontal regeneration.
- Principal Investigator
  
  OGATA Yorimasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Nihon University
Mechanism of gene expression of bone sialoprotein and transcription factors which control periodontal regeneration
- Principal Investigator
  
  OGATA Yorimasa
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Nihon University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Epstein-Barr Virus Promotes the Production of Inflammatory Cytokines in Gingival Fibroblasts and RANKL-Induced Osteoclast Differentiation in RAW264.7 Cells.2022
- Author(s)
  Yokoe S, Hasuike A, Watanabe N, Tanaka H, Karahashi H, Wakuda S, Takeichi O, Kawato T, Takai H, Ogata Y, Sato S, Imai K
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 23(2) Issue: 2 Pages: 80-80
- DOI
  10.3390/ijms23020809
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10078, KAKENHI-PROJECT-20K09945, KAKENHI-PROJECT-20K09980
[Journal Article] TNF-α regulates the composition of the basal lamina and cell-matrix adhesions in gingival epithelial cells2022
- Author(s)
  Mezawa M, Tsuruya Y, Yamaguchi A, Yamazaki-Takai M, Kono T, Okada H, McCulloch CA, Ogata Y
- Journal Title
  
  Cell Adhesion & Migration
  
  Volume: 16 Issue: 1 Pages: 13-24
- DOI
  10.1080/19336918.2022.2029237
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09945
[Journal Article] Transcriptional regulation of human odontogenic ameloblast-associated protein gene by tumor necrosis factor-α2022
- Author(s)
  Tsuruya Y, Yamaguchi A, Yamazaki-Takai M, Mezawa M, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  Inflammation Research
  
  Volume: 71 Issue: 1 Pages: 119-129
- DOI
  10.1007/s00011-021-01523-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09945, KAKENHI-PROJECT-21K16976
[Journal Article] MicroRNA-141 and miR-200a induce the chondrogenic cell fate in human periodontal ligament cells by targeting TWIST2 and KLF122021
- Author(s)
  Hideki Takai, Andre J. van Wijnen, Yorimasa Ogata
- Journal Title
  
  Gene Reports
  
  Volume: 25 Pages: 101414-101414
- DOI
  10.1016/j.genrep.2021.101414
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09922
[Journal Article] Prospective Longitudinal Changes in the Periodontal Inflamed Surface Area Following Active Periodontal Treatment for Chronic Periodontitis2021
- Author(s)
  Nomura Y, Morozumi T*, Saito A, Yoshimura A, Kakuta E, Suzuki F, Nishimura F, Takai H, Kobayashi H, Noguchi K, Takahashi K, Tabeta K, Umeda M, Minabe M, Fukuda M, Sugano N, Hanada N, Yoshinari N, Sekino S, Takashiba S, Sato S, Nakamura T, Sugaya T, Nakayama Y, Ogata Y, Numabe Y, Nakagawa T
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 6 Pages: 1165-1165
- DOI
  10.3390/jcm10061165
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-19K10124, KAKENHI-PROJECT-20K10303, KAKENHI-PROJECT-20K09945
[Journal Article] Anti-heat shock protein 70 levels in gingival crevicular fluid of Japanese patients with chronic periodontitis2020
- Author(s)
  Takai H, Furuse N, Ogata Y
- Journal Title
  
  Journal of Oral Science
  
  Volume: 62 Issue: 3 Pages: 281-284
- DOI
  10.2334/josnusd.19-0159
- NAID
  130007863797
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09945
[Journal Article] Optimal Examination Sites for Periodontal Disease Evaluation: Applying the Item Response Theory Graded Response Model2020
- Author(s)
  Nomura Y, Morozumi T*, Fukuda M, Hanada N, Kakuta E, Kobayashi H, Minabe M, Nakamura T, Nakayama Y, Nishimura F, Noguchi K, Numabe Y, Ogata Y, Saito A, Sato S, Sekino S, Sugano N, Sugaya T, Suzuki F, Takahashi K, Takai H, Takashiba S, Umeda M, Yoshie H, Yoshimura A, Yoshinari N, Nakagawa T
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 11 Pages: 3754-3754
- DOI
  10.3390/jcm9113754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11984, KAKENHI-PROJECT-19K10124, KAKENHI-PROJECT-19K10454, KAKENHI-PROJECT-19K10471, KAKENHI-PROJECT-20K09942, KAKENHI-PROJECT-20K09945
[Journal Article] MiR-200b suppresses TNF-α-induced AMTN production in human gingival epithelial cells.2020
- Author(s)
  Yamazaki-Takai M, Takai H, Iwai Y, Noda K, Mezawa M, Tsuruya Y, Yamaguchi A, Nakayama Y, Ogata Y
- Journal Title
  
  Odontology
  
  Volume: 109 Issue: 2 Pages: 403-410
- DOI
  10.1007/s10266-020-00555-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09945
[Journal Article] Effects of Initial Periodontal Therapy on Heat Shock Protein 70 Levels in Gingival Crevicular Fluid from Periodontitis Patients.2020
- Author(s)
  Furuse N, Takai H, Ogata Y
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 10 Pages: 3072-3072
- DOI
  10.3390/jcm9103072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09945
[Journal Article] IL-1β enhances cell adhesion through laminin 5 and β4 integrin in gingival epithelial cells2019
- Author(s)
  Mezawa M, Tsuruya Y, Yamazaki-Takai M, Takai H, Nakayama Y, McCulloch CA, Ogata Y.
- Journal Title
  
  Journal of Oral Science
  
  Volume: 61 Issue: 4 Pages: 491-497
- DOI
  10.2334/josnusd.18-0434
- NAID
  130007751577
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09582, KAKENHI-PROJECT-17K11994
[Journal Article] Induction of chondrogenic or mesenchymal stem cells from human periodontal ligament cells through inhibition of Twist2 or Klf122019
- Author(s)
  Takai H, Van Wijnen AJ, Ogata Y.
- Journal Title
  
  Journal of Oral Science
  
  Volume: 61 Issue: 2 Pages: 313-320
- DOI
  10.2334/josnusd.18-0224
- NAID
  130007664889
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09583, KAKENHI-PROJECT-17K11994
[Journal Article] Negative feedback by SNAI2 regulates TGFβ1-induced amelotin gene transcription in epithelial-mesenchymal transition.2019
- Author(s)
  Nakayama Y, Tsuruya Y, Noda K, Yamazaki-Takai M, Iwai Y, Ganss B, Ogata Y.
- Journal Title
  
  J Cell Physiol.
  
  Volume: 234 Issue: 7 Pages: 11474-11489
- DOI
  10.1002/jcp.27804
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09582, KAKENHI-PROJECT-17K11994
[Journal Article] IL-1β and TNF-α regulate mouse amelotin gene transcription in gingival epithelial cells.2018
- Author(s)
  Noda K, Yamazaki M, Iwai Y, Matsui S, Kato A, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  J Oral Sci
  
  Volume: 60 Issue: 3 Pages: 388-398
- DOI
  10.2334/josnusd.17-0388
- NAID
  130007485938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-18K09582
[Journal Article] Transcriptional regulation of human amelotin gene by interleukin-1β.2018
- Author(s)
  Yamazaki M, Mezawa M, Noda K, Iwai Y, Matsui S, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 6 Pages: 974-985
- DOI
  10.1002/2211-5463.12434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-18K09582
[Journal Article] MiR-200b attenuates IL-6 production through IKKβ and ZEB1 in human gingival fibroblasts.2018
- Author(s)
  Matsui S, Zhou L, Nakayama Y, Mezawa M, Kato A, Suzuki N, Tanabe N, Nakayama T, Suzuki Y, Kamio N, Takai H, Ogata Y
- Journal Title
  
  Inflamm Res
  
  Volume: 67 Issue: 11-12 Pages: 965-973
- DOI
  10.1007/s00011-018-1192-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-18K05980, KAKENHI-PROJECT-18K09582, KAKENHI-PROJECT-18K09920, KAKENHI-PUBLICLY-17H05824, KAKENHI-PROJECT-16K11526
[Journal Article] Effects of interleukin-1β on human follicular dendritic cell-secreted protein gene expression in periodontal ligament cells2018
- Author(s)
  Iwai Y, Noda K, Yamazaki M, Mezawa M, Takai H, Nakayama Y, Kitagawa M, Takata T, Ogata Y
- Journal Title
  
  Journal of Oral Science
  
  Volume: 60 Issue: 4 Pages: 601-610
- DOI
  10.2334/josnusd.17-0473
- NAID
  130007553038
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-18K09582
[Journal Article] Tumor necrosis factor-α regulates human follicular dendritic cell-secreted protein gene transcription in gingival epithelial cells.2018
- Author(s)
  Iwai Y, Noda K, Yamazaki M, Kato A, Mezawa M, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  Genes Cells
  
  Volume: 23 Issue: 3 Pages: 161-171
- DOI
  10.1111/gtc.12561
- Open Access
- Data Source
  KAKENHI-PROJECT-17K11994
[Journal Article] Tumor necrosis factor-α stimulates human amelotin gene transcription in gingival epithelial cells.2018
- Author(s)
  Yamazaki M, Iwai Y, Noda K, Matsui S, Kato A, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  Inflammation Res
  
  Volume: 67 Issue: 4 Pages: 351-361
- DOI
  10.1007/s00011-017-1126-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11994, KAKENHI-PROJECT-18K09582
[Journal Article] Insulin-like growth factor-II regulates bone sialoprotein gene transcription.2016
- Author(s)
  Choe J, Sasaki Y, Zhou L, Takai H, Nakayama Y, Ogata Y
- Journal Title
  
  Odontology
  
  Volume: 104
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Effects of initial periodontal therapy on interleukin-1β level in gingival crevicular fluid and clinical periodontal parameters2015
- Author(s)
  Oh H, Hirano J, Takai H, Ogata Y
- Journal Title
  
  Journal of Oral Science
  
  Volume: 57 Issue: 2 Pages: 67-71
- DOI
  10.2334/josnusd.57.67
- NAID
  130005076037
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Proinflammatory cytokines induce amelotin transcription in human gingival fibroblasts2014
- Author(s)
  Nakayama Y, Takai H, Matsui S, Matsumura H, Zhou L, Kato A, Bernhard Ganss B, Ogata Y
- Journal Title
  
  Journal of Oral Science
  
  Volume: 56 Issue: 4 Pages: 261-268
- DOI
  10.2334/josnusd.56.261
- NAID
  130004705235
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Unliganded estrogen receptor alpha stimulates bone sialoprotein gene expression.2014
- Author(s)
  H. Takai, H. Matsumura, S. Matsui, KM. Kim, M. Mezawa, Y. Nakayama, Y. Ogata
- Journal Title
  
  Gene
  
  Volume: 539 Issue: 1 Pages: 50-57
- DOI
  10.1016/j.gene.2014.01.063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Effects of interleukin-11 on the expression of human bone sialoprotein gene2014
- Author(s)
  H. Matsumura, Y. Nakayama, H. Takai, Y. Ogata
- Journal Title
  
  J Bone Miner Metab
  
  Volume: 32 Issue: 2 Pages: 1-12
- DOI
  10.1007/s00774-014-0576-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Transcriptional regulation of amelotin gene by proinflammatory cytokines in gingival fibroblasts.2014
- Author(s)
  Nakayama Y, Takai H, Matsui S, Zhou L, Abiko Y, Ganss B, Ogata Y.
- Journal Title
  
  Connect Tissue Res
  
  Volume: 55 Suppl 1 Issue: sup1 Pages: 18-20
- DOI
  10.3109/03008207.2014.923848
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] MicroRNA expression in inflamed and noninflamed gingival tissues from Japanese patients2014
- Author(s)
  Ogata Y, Matsui S, Kato A, Zhou L, Nakayama Y, Takai H
- Journal Title
  
  J Oral Sci
  
  Volume: 56 Pages: 253-260
- NAID
  130004705234
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Osteogenic transcription factors and proto-oncogene regulate bone sialoprotein gene transcription2013
- Author(s)
  H. Takai, M. Mezawa, J. Choe, Y. Nakayama, Y. Ogata
- Journal Title
  
  J Oral Science
  
  Volume: 55 Pages: 209-215
- NAID
  130003366676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25463229
[Journal Article] Protamine stimulates bone sialoprotein gene expression.2013
- Author(s)
  Zhou L, Matsumura H, Mezawa M, Takai H, Nakayama Y, Mitarai M, Ogata Y.
- Journal Title
  
  Gene
  
  Volume: 516 Issue: 2 Pages: 228-237
- DOI
  10.1016/j.gene.2012.12.056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592319
[Journal Article] Aggregatibacter actinomycetemcomitans lipopolysaccharide regulates bone sialoprotein gene transcription.2012
- Author(s)
  Li X, Zhou L, Takai H, Sasaki Y, Mezawa M, Li Z, Wang Z, Yang L, Wang S, Matsumura H, Kaneko T, Yoshimura A, Ogata Y.
- Journal Title
  
  J Cell Biochem
  
  Volume: 113 Issue: 9 Pages: 2822-2834
- DOI
  10.1002/jcb.24157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592319, KAKENHI-PROJECT-24593126
[Journal Article] Fibroblast growth factor 2 and forskolin induce mineralization-associated genes in two kinds of osteoblast-like cells.2012
- Author(s)
  Nakayama Y, Yang L, Takai H, Kaneko H, Abiko Y, Ogata Y.
- Journal Title
  
  J Oral Sci
  
  Volume: 54 Pages: 251-259
- NAID
  130002070048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592319
[Journal Article] Parathyroid hormone regulation of the human bone sialoprotein gene transcription is mediated through two cAMP response elements2009
- Author(s)
  S. Araki, M. Mezawa, Y. Sasaki, L. Yang, Z. Li, H. Takai, Y. Nakayama, Y. Ogata
- Journal Title
  
  J. Cell. Biochem 106
  
  Pages: 618-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] Regulation of human bone sialoprotein gene transcription by platelet-derived growth factor-BB2009
- Author(s)
  M. Mezawa, S. Araki, H. Takai, Y. Sasaki, S. Wang, X. Li, D. Kim, Y. Nakayama, Y. Ogata
- Journal Title
  
  Gene 435
  
  Pages: 80-87
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] AP1 Binding Site is Another Target of FGF2 Regulation of Bone Sialoprotein Gene Transcription2008
- Author(s)
  H. Takai, S. Araki, M. Mezawa, D. Kim, X. Li, L. Yang, Z. Li, Z. Wang, Y. Nakayama and Y. Ogata
- Journal Title
  
  Gene 410
  
  Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] AP1 binding site is another target of FGF2 regulation of bone sialoprotein gene transcription.2008
- Author(s)
  Hideki Takai, et al.
- Journal Title
  
  Gene 410
  
  Pages: 97-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] 骨シアロタンパク質(BSP)遺伝子の転写に対するアンドロゲン受容体の効果2007
- Author(s)
  高井英樹, 小方頼昌
- Journal Title
  
  日本歯周病学会会誌 49
  
  Pages: 27-36
- NAID
  10027094023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] 骨シアロタンパク質(BSP)遺伝子の転写に対するアンドドゲン受容体の効果2007
- Author(s)
  高井英樹, 小方頼昌
- Journal Title
  
  日本歯周誌 49
  
  Pages: 27-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] Androgen Receptor Stimulates Bone Sialoprotein(BSP)Gene Transcription via cAMP Response Element and Activator Protein/Glucocorticoid Respose Element.2007
- Author(s)
  Hideki Takai, et. al.
- Journal Title
  
  Journal of Cellular Biochenistry 102
  
  Pages: 240-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] Effects of Quercetin and Quercetin 3-Glucuronide on the Expression of Bone Sialoprotein Gene2007
- Author(s)
  D. Kim, H. Takai, M. Arai, S. Araki, M. Mezawa, Y. Kawai, K. Murota, J. Terao and Y. Ogata
- Journal Title
  
  Journal of Cellular Biochemistry 101
  
  Pages: 790-800
- NAID
  130004570777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] Androgen Receptor stimulates Bone Sialoprotein (BSP) Gene Transcription via cAMP response element and activator protein 1/glucocorticoid response elements2007
- Author(s)
  H. Takai, Y. Nakayama, D. Kim, M. Arai, S. Araki, M. Mezawa, Y. Nakajima, N. Kato, H. Masunaga and Y. Ogata
- Journal Title
  
  Journal of Cellular Biochemistry 102
  
  Pages: 240-251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390563
[Journal Article] Androgen receptor stimulates bone sialoprotein (BSP) gene transcription via CAMP response element and activator protein 1/Glucocorticoid response elements.2007
- Author(s)
  Takai Hideki, et al.
- Journal Title
  
  Journal of Cellular Biochemistry (印刷中)
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] 歯周基本治療前後における唾液中のエクソソーム内の成分の変化2021
- Author(s)
  山口亜利彩，鶴屋祐人，高井瑞穂，目澤優，高井英樹，中山洋平，小方賴昌
- Organizer
  第64回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] 歯肉線維芽細胞に高発現する転写因子阻害によるヒト歯肉線維芽細胞からの骨形成細胞へ2021
- Author(s)
  高井英樹、小方賴昌
- Organizer
  第64回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-21K09922
[Presentation] FDC-SP遺伝子発現に対するIL-6の影響2021
- Author(s)
  鶴屋祐人，山口亜利彩，高井瑞穂，目澤優，高井英樹，中山洋平，小方賴昌
- Organizer
  第64回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] 歯周基本治療が歯周病患者の唾液中エクソソーム内の成分に与える影響2021
- Author(s)
  山口亜利彩，鶴屋祐人，金振宇，高井瑞穂, 高井英樹，中山洋平，小方賴昌
- Organizer
  第64回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] ニフェジピンによる薬物性歯肉増殖症歯肉における接合上皮特異的遺伝子の発現2020
- Author(s)
  中山洋平，井上英子，加藤彩子，岩井泰伸，高井瑞穂，鶴屋祐人，山口亜利彩，能田佳祐，小方頼昌
- Organizer
  第63回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] GRADEアプローチを用いた診療ガイドライン策定の試み ① インプラント周囲炎に対する外科的処置時に経口抗菌療法は有効ですか？2020
- Author(s)
  高井英樹、目澤優、中山洋平、小方頼昌、高橋慶壮
- Organizer
  第63回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] 歯周炎が唾液中のエクソソーム内の成分に及ぼす影響2020
- Author(s)
  3.山口　亜利彩，鶴屋　祐人，高井　瑞穂，目澤　優，高井　英樹，中山　洋平，小方　賴昌
- Organizer
  第63回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] IL-1βとTNF-αは歯肉上皮細胞におけるODAM遺伝子の転写を調節する2020
- Author(s)
  鶴屋祐人，山口亜利彩，高井瑞穂，目澤優，高井英樹，中山洋平，小方賴昌
- Organizer
  第63回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-20K09945
[Presentation] MiR-200b inhibits IL-6 expression through IKKβ and ZEB1 in human gingival fibroblasts.2019
- Author(s)
  Ogata Y, Nakayama Y, Mezawa M, Suzuki N, Tanabe N, Nakayama T, Suzuki Y, Kamio N, Kato A, Takai H, Matsui S
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] miR-200bはヒト歯肉上皮細胞におけるアメロチン遺伝子発現を抑制する2019
- Author(s)
  高井瑞穂、能田佳祐、岩井泰伸、目澤優、高井英樹、中山洋平、小方頼昌
- Organizer
  第62回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] SNAI2は上皮間葉移行におけるTGFβ1誘導AMTN遺伝子の発現を負に調節する2019
- Author(s)
  中山洋平、鶴屋祐人、能田佳祐、高井瑞穂、岩井泰伸、小方頼昌
- Organizer
  第62回春季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Twist2またはKif12阻害によるヒト歯根膜細胞からの軟骨形成または間葉系幹細胞への誘導2019
- Author(s)
  高井英樹、小方頼昌
- Organizer
  第62回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] miR-150はヒト歯肉上皮細胞においてMKP-5を介してマウスアメロチン遺伝子発現を調節する2019
- Author(s)
  能田佳祐、高井瑞穂、岩井泰伸、目澤優、高井英樹、中山洋平、小方頼昌
- Organizer
  第62回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] 炎症性サイトカインによるODAM転写調節機構の解析2019
- Author(s)
  鶴屋祐人、山口亜利彩、能田佳祐、高井瑞穂、目澤優、高井英樹、中山洋平、小方頼昌
- Organizer
  第62回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Twist2またはKlf12阻害によるヒト歯根膜細胞からの軟骨形成または間葉系幹細胞への誘導2019
- Author(s)
  高井英樹、小方頼昌
- Organizer
  第62回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09583
[Presentation] 炎症性サイトカインがエクソソームに及ぼす影響2019
- Author(s)
  山口亜利彩、鶴屋祐人、能田佳祐、高井瑞穂、目澤優、高井英樹、中山洋平、小方頼昌
- Organizer
  第62回秋季日本歯周病学会
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Induction of chondrogenic or mesenchymal stem cells from human periodontal ligament cells through inhibition of Twist2 or Klf122019
- Author(s)
  Takai H, Ogata Y
- Organizer
  13th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09583
[Presentation] miRNAによる歯根膜細胞の軟骨細胞への分化誘導2018
- Author(s)
  高井英樹、小方頼昌
- Organizer
  第61回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09583
[Presentation] MicroRNA expression in inflamed gingival tissues and effects of miR-200b on the expression of Interleukin-6 in human gingival fibroblasts.2018
- Author(s)
  Ogata Y, Nakayama Y, Kato A, Mezawa M, Suzuki N, Tanabe N, Nakayama T, Suzuki Y, Kamio N, Takai H, Matsui S
- Organizer
  EuroPerio9
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Effects of TNF-α on the expression human FDC-SP gene in gingival epithelial cells.2017
- Author(s)
  Iwai Y, Noda K, Yamazaki M, Matsui S, Kato A, Takai H, Nakayama Y, Ogata Y
- Organizer
  12th International Conference on the Chemistry and Biology of Mineralized Tissues
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] MicroRNA expression in inflamed gingival tissues and the effects of miR-223 on expression of inflammatory cytokines in human gingival fibroblasts.2017
- Author(s)
  Ogata Y, Nakayama Y, Kato A, Mezawa M, Suzuki N, Tanabe N, Nakayama T, Suzuki Y, Kamio N, Takai H, Matsui S
- Organizer
  12th Asian Pacific Society of Periodontology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Comparative study of transcriptional regulation of bone sialoprotein in osteoblast- and cementoblast-like cells.2017
- Author(s)
  Noda K, Yamazaki M, Iwai Y, Matsui S, Kato A, Takai H, Nakayama Y, Ogata Y
- Organizer
  12th International Conference on the Chemistry and Biology of Mineralized Tissues
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] Inflammatory cytokines regulate human AMTN gene transcription in gingival epithelial cells.2017
- Author(s)
  Yamazaki M, Iwai Y, Noda K, Matsui S, Kato A, Takai H, Nakayama Y, Ogata Y
- Organizer
  12th International Conference on the Chemistry and Biology of Mineralized Tissues
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11994
[Presentation] 歯周組織構成細胞関連転写因子の抑制による軟骨芽細胞への誘導2016
- Author(s)
  高井英樹
- Organizer
  第144回春季日本歯科保存学会
- Place of Presentation
  栃木県総合文化センター（栃木県・宇都宮）
- Year and Date
  2016-06-09
- Data Source
  KAKENHI-PROJECT-15K20631
[Presentation] 歯周組織構成細胞関連転写因子の抑制による軟骨および間葉系幹細胞への誘導2016
- Author(s)
  高井英樹
- Organizer
  第59回秋季日本歯周病学会
- Place of Presentation
  朱鷺メッセ（新潟・新潟）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K20631
[Presentation] Inhibition of periodontal tissue-related transcription factors induces differentiation of chondrocyte2016
- Author(s)
  Hideki Takai
- Organizer
  102nd Annual Meeting of the AAP
- Place of Presentation
  San Diego (America）
- Year and Date
  2016-09-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K20631
[Presentation] 歯周組織構成細胞関連転写因子の抑制による軟骨芽細胞への誘導2015
- Author(s)
  高井英樹
- Organizer
  第58回秋季日本歯周病学会
- Place of Presentation
  アクトシティー浜松（静岡県・浜松市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K20631
[Presentation] Effects of miRNAs on the expression of inflammatory cytokines in human gingival fibroblasts.2015
- Author(s)
  Sari Matsui, Hideki Takai and Yorimasa Ogata
- Organizer
  EuroPerio8
- Place of Presentation
  London （England）
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] 慢性歯周炎歯肉で発現が増加したmiR-223による炎症性サイトカイン発現の調節．2015
- Author(s)
  松井沙莉、高井英樹、小方頼昌
- Organizer
  第58回春季日本歯周病学会学術大会
- Place of Presentation
  幕張メッセ（千葉県千葉市）
- Year and Date
  2015-05-15
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] Proinflammatory Cytokines Induce Amelotin Transcription in Human Gingival Fibroblasts.2013
- Author(s)
  Y. Nakayama, H. Takai, S. Matsui, L. Zhou, Y. Abiko, B. Ganss, Y. Ogata
- Organizer
  11th ICCBMT
- Place of Presentation
  Wisconsin, USA
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] Inhibition of stem cell-specific transcription factors induces differentiation of preosteoblasts.2013
- Author(s)
  Ｈ. Takai ＡＪ. van Wijnen, Y. Ogata
- Organizer
  IADR-APR 2013
- Place of Presentation
  Bangkok,Thailand
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] Melatonin Regulates Human Bone Sialoprotein Gene Transcription.2013
- Author(s)
  Ｈ. Matsumura, Y. Nakayama, H. Takai, Y. Ogata
- Organizer
  IADR-APR 2013
- Place of Presentation
  Bangkok,Thailand
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] Mitotic transcription factor circuits control the molecular phenotype of mesenchymal cells.2012
- Author(s)
  Takai H, van Wijnen AJ, Ogata Y.
- Organizer
  JADR meeting
- Place of Presentation
  Niigata
- Data Source
  KAKENHI-PROJECT-22592319
[Presentation] Mitotic transcription factor circuits control the molecular phenotype of mesenchymal cells.2012
- Author(s)
  Hideki Takai
- Organizer
  Japanese Association for Dental Research
- Place of Presentation
  Niigata, Japan
- Data Source
  KAKENHI-PROJECT-22592319
[Presentation] Transcriptional Regulation of Bone Sialoprotein Gene by Aggregatibacter actinomycetemcomitans Lipopolysaccharide.2012
- Author(s)
  Ogata Y, Takai H, Zhou L, Matsumura H, Li X.
- Organizer
  IADR meeting
- Place of Presentation
  Brazil
- Data Source
  KAKENHI-PROJECT-22592319
[Presentation] Androgen Receptor Regulates Bone Sialoprotein Gene Expression2008
- Author(s)
  H, Takai, Y, Nakayama, D, Kim, S, Araki, M, Mezawa, N, Kato, Y, Ogata
- Organizer
  IADR General Session
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] Androgen Receptor Regulates Bone Sialoprotein Gene Expression.2008
- Author(s)
  Hideki Takai, et al.
- Organizer
  International Association for Dental Research
- Place of Presentation
  Toronto, Canada
- Year and Date
  2008-07-03
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] cAMP Regulates BSP Expression in Human Breast Cancer Cells2008
- Author(s)
  D. Kim, H. Takai, N. Kato, Y. Sasaki, S. Wang, Y. Nakayama, Y. Ogata
- Organizer
  IADR General Session
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] Insulin-like growth Factor-I regulates bone sialoprotein gene expression2007
- Author(s)
  Y. Nakayama, N. Kato, H. Takai, D. Kim, M. Arai, S. Araki, M.Mezawa, Y. Ogata
- Organizer
  9th International Conference of Chemistry and Biology of Mineralized Tissues
- Place of Presentation
  Austin USA
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] Regulation of human bone sialoprotein gene transcription by platelet-derived growth factor2007
- Author(s)
  M. Mezawa, S. Araki, D. Kim, H. Takai, Z. Wang, X. Li, N. Kato, Y.Nakayama, Y. Ogata
- Organizer
  9th International Conference of Chemistry and Biology of Mineralized Tissues
- Place of Presentation
  Austin USA
- Data Source
  KAKENHI-PROJECT-18390563
[Presentation] Regulation of Amelotin gene transcription by Proinflammatory Cytokines in Gingival Fibroblasts
- Author(s)
  Nakayama Y, Takai H, Matsui S, Zhou L, Abiko Y, Ganss B, Ogata Y
- Organizer
  54th General Session of Korean Academy of Periodontology
- Place of Presentation
  Seoul
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25463229
[Presentation] Effects of Osteogenic Transcription Factors and Proto-oncogene on Bone Sialoprotein Gene Transcription
- Author(s)
  Takai H, Mezawa M, Nakayama Y, Ogata Y
- Organizer
  92nd General Session & Exhibition of the IADR
- Place of Presentation
  Cape Town, South Africa
- Year and Date
  2014-06-25 – 2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-25463229

1. OGATA Yorimasa (90204065)

# of Collaborated Projects: 8 results

# of Collaborated Products: 63 results
2. NAKAYAMA Yohei (30434088)

# of Collaborated Projects: 5 results

# of Collaborated Products: 44 results
3. NAKAO Sumi (20102577)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MASUNAGA Hiroshi (40229381)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. MATSUMURA Hiroyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. MATSUI Sari

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. KATO Ayako

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MOROZUMI Toshiya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 高橋直紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 今井健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takai Hideki 高井 英樹

TAKAI Hideki 高井 英樹

Research Projects

Research Products

Co-Researchers

Elucidation of the roles of junctional epithelial proteins and salivary exosomes as diagnostic markers for periodontal disease

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miRNAを用いた転写因子制御による歯周組織関連細胞の分化誘導Principal Investigator

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接合上皮発現タンパク質の発現制御による歯周病治療戦略

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Induction of differentiation of periodontal tissue constituent cells by regulating expression of miRNAPrincipal Investigator

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Strategy for prevention of periodontal disease by controlling protein expressions of junctional epithelium expressed proteins

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Analysis of transcription factors involved in the differentiation induction of periodontal tissue constituent cellsPrincipal Investigator

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Mechanistic analysis of onset and progress of periodontitis causing microRNA

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Analysis of involved specific transcription factor to differentiation Induction at periodontal tissue component cellsPrincipal Investigator

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Mechanism of transcriptional regulation of extracellular matrix and transcription factors which control periodontal regeneration.

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Mechanism of gene expression of bone sialoprotein and transcription factors which control periodontal regeneration

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[Journal Article] Epstein-Barr Virus Promotes the Production of Inflammatory Cytokines in Gingival Fibroblasts and RANKL-Induced Osteoclast Differentiation in RAW264.7 Cells.2022

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[Journal Article] TNF-α regulates the composition of the basal lamina and cell-matrix adhesions in gingival epithelial cells2022

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[Journal Article] Transcriptional regulation of human odontogenic ameloblast-associated protein gene by tumor necrosis factor-α2022

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Takai Hideki 高井英樹

TAKAI Hideki 高井英樹