FUKUSHIMA Keizo 福島恵造

… Alternative Names

福島恵造フクシマケイゾウ

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Researcher Number	30454474
Other IDs
Affiliation (Current)	2025: 神戸学院大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 神戸学院大学, 薬学部, 准教授 2019 – 2023: 神戸学院大学, 薬学部, 講師 2012 – 2018: 神戸学院大学, 薬学部, 助教 2011: 神戸学院大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 59040:Nutrition science and health science-related / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Medical pharmacy
Keywords	Principal Investigator シスプラチン / 薬物動態 / 個別化設計 / 投与速度 / 脂肪乳剤 / 副作用 / Pharmcometrics / 慢性腎障害 / Pharmacometrics / 母集団解析 … More / 慢性腎毒性 / 反復投与 / 腎毒性 / PKPD modeling / cisplatin / PKPD解析 / 強制利尿法 / 腎障害 / 栄養療法 / 小腸萎縮 / 中心静脈栄養 / 薬物代謝酵素 / P糖タンパク / バンコマイシン / 薬物代謝 / TPN / 代謝 / 吸収 / 経腸静脈栄養 / 消化管萎縮 … More Except Principal Investigator 免疫抑制剤 / 治療薬物モニタリング / 赤血球移行 / TDM / 血中濃度 / 超臨界抽出-クロマトグラフィー/質量分析システム / 造血幹細胞移植 / 母集団薬物動態解析 / タクロリムス / 脂質・蛋白酸化 / 脂質・蛋白過酸化 / 酸化ストレス / 薬物動態変動 Less

脂肪乳剤個別化投与速度設計の臨床実装を目的とした多施設共同研究Principal Investigator
- Principal Investigator
  
  福島恵造
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kobe Gakuin University
造血幹細胞移植における赤血球数変動を考慮したタクロリムスの全血中濃度再評価
- Principal Investigator
  
  杉岡信幸
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kobe Gakuin University
Prediction of cisplatin-induced nephrotoxicity in multicycle and exploration of risk factorsPrincipal Investigator
- Principal Investigator
  
  Fukushima Keizo
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Kobe Gakuin University
Pharmakokinetic-pharmacodynamic analysis of cisplatin with hydration and mannitol diuresisPrincipal Investigator
- Principal Investigator
  
  Fukushima Keizo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kobe Gakuin University
Pharmacokinetic assessment of intestinal atrophy induced by long-term parenteral nutritionPrincipal Investigator
- Principal Investigator
  
  FUKUSHIMA Keizo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kobe Gakuin University
Elucidation of the mechanism of pharmacokinetic change by lipid-, protein-oxidation and glycation, and its clinical application
- Principal Investigator
  
  SUGIOKA Nobuyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kobe Gakuin University

All 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011

All Journal Article Presentation

[Journal Article] Comparison of cisplatin-induced nephrotoxicity between single-dose and split-dose administration to rats2022
- Author(s)
  Fukushima Keizo、Futatsugi Azusa、Maekawa Maiko、Naito Saya、Okada Akira、Sugioka Nobuyuki
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 147 Pages: 112619-112619
- DOI
  10.1016/j.biopha.2022.112619
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06771
[Journal Article] Population pharmacokinetics of tacrolimus in umbilical cord blood transplant patients focusing on the variation in red blood cell counts2021
- Author(s)
  Yoshida S, Fujimoto A, Fukushima K, Ando M, Irie K, Hirano T, Miyasaka M, Shimomura Y, Ishikawa T, Ikesue H, Muroi N, Hashida T, Sugioka N.
- Journal Title
  
  J Clin Pharm Ther .
  
  Volume: 46 Issue: 1 Pages: 190-197
- DOI
  10.1111/jcpt.13279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07180
[Journal Article] Pharmacokinetic-Pharmacodynamic Analysis of Cisplatin with Hydration and Mannitol Diuresis: The Contribution of Urine Cisplatin Concentration to Nephrotoxicity.2018
- Author(s)
  Fukushima K, Okada A, Oe H, Hirasaki M, Hamori M, Nishimura A, Shibata N, Sugioka N.
- Journal Title
  
  Eur J Drug Metab Pharmacokinet
  
  Volume: 43 Issue: 2 Pages: 193-203
- DOI
  10.1007/s13318-017-0436-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18941
[Journal Article] Population Pharmacokinetic-Toxicodynamic Modeling and Simulation of Cisplatin-Induced Acute Renal Injury in Rats: Effect of Dosing Rate on Nephrotoxicity.2016
- Author(s)
  Fukushima K, Okada A, Sasaki K, Kishimoto S, Fukushima S, Hamori M, Nishimura A, Shibata N, Shirai T, Terauchi R, Kubo T, Sugioka N.
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 105 Issue: 1 Pages: 324-332
- DOI
  10.1016/j.xphs.2015.10.022
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18941
[Journal Article] Effect of Intestinal Atrophy and Hepatic Impairment Induced by Parenteral Nutrition on Drug Absorption and Disposition in Rats.2013
- Author(s)
  Fukushima K, Miki T, Nakamoto K, Nishimura A, Koyama H, Ichikawa H, Shibata N, Tokuyama S, Sugioka N.
- Journal Title
  
  JPEN J Parenter Enteral Nutr.
  
  Volume: ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790178
[Journal Article] Effects of obesity induced by high-fat diet on the pharmacokinetics of cyclosporine A in rats.2011
- Author(s)
  Fukushima K, Yoshida K, Ito Y, Takada K, Sugioka N.
- Journal Title
  
  Biomed Prev Nutri.
  
  Volume: 1 Issue: 3 Pages: 195-201
- DOI
  10.1016/j.bionut.2011.06.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590211
[Journal Article] Effects of obesity induced by high-fat diet on the pharmacokinetics of cyclosporine A in rats2011
- Author(s)
  Fukushima K, Yoshida K, Ito Y, Takada K, Sugioka N
- Journal Title
  
  Biomed Prev Nutri
  
  Volume: 1(3) Pages: 195-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590211
[Presentation] タクロリムスの全血/血漿中濃度比モデルのin vitro-in vivo外挿性の比較2023
- Author(s)
  奥遥乃、御木駿斗、坂元笑菜、中谷汀歩、二木梓、西村亜佐子、福島恵造、芝田信人、杉岡信幸
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] 糖尿病モデルラットにおけるタクロリムスの脳移行性評価2023
- Author(s)
  奥遥乃、吉川真衣、横田詩子、二木梓、福島恵造、杉岡信幸
- Organizer
  第11回日本くすりと糖尿病学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] In vitroデータを用いたin vivoタクロリムスの全血/血漿中濃度比の予測2022
- Author(s)
  奥　遥乃、二木　梓、安永　明弘、森本　紗加、岩佐　蓉子、池内　綾菜、坂元　笑菜、羽森　真美、西村　亜佐子、福島　恵造、芝田　信人、杉岡　信幸
- Organizer
  第143回日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] 超臨界抽出-クロマトグラフィー/質量分析システムを用いた全血および血漿中タクロリムス濃度の超高感度定量方法開発と応用2021
- Author(s)
  西村亜佐子、岩佐蓉子、池内綾菜、福島恵造、杉岡信幸、羽森真美、芝田信人
- Organizer
  第142年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] Cisplatin反復投与時における腎障害の予測2020
- Author(s)
  丸岡由奈、堀田拓海、福島恵造、杉岡信幸
- Organizer
  第140年会日本薬学会 2020年 3月 (京都)
- Data Source
  KAKENHI-PROJECT-18K06771
[Presentation] 造血幹細胞移植患者におけるタクロリムスの母集団薬物動態解析及び移植レジメンの影響評価2020
- Author(s)
  奥　遥乃、吉田早希、福島恵造、入江　慶、平野達也、室井延之、池末裕明、橋田　亨、杉岡信幸
- Organizer
  第141年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] 一括投与時と分割投与時のCisplatin誘発性腎毒性の比較検討2020
- Author(s)
  前川真衣子、内藤清、福島恵造、杉岡信幸
- Organizer
  第140年会日本薬学会 2020年 3月 (京都)
- Data Source
  KAKENHI-PROJECT-18K06771
[Presentation] 造血幹細胞移植におけるタクロリムスの母集団薬物動態解析2019
- Author(s)
  藤中俊輔、吉田早希、磯部ひかる、福島恵造、安藤基純、平野達也、下村良充、池末裕明、室井延之、石川隆之、橋田亨、杉岡信幸
- Organizer
  第140年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] PopPKPD Analysis of Cisplatin Induced Nephrotoxicity: An Apoptotic Signal Transduction-Indirect Response Model2019
- Author(s)
  Keizo Fukushima
- Organizer
  第二回Pharmacometrics Japan Conference 2019
- Data Source
  KAKENHI-PROJECT-18K06771
[Presentation] シスプラチン反復投与時における腎障害の進行予測および影響因子の探索2019
- Author(s)
  堀田拓海, 井澤春香, 福島恵造, 池村舞, 安藤基純, 富井啓介, 池末裕明, 橋田亮, 杉岡信幸
- Organizer
  第29回　日本医療薬学会年会　2019年 11月 (福岡)
- Data Source
  KAKENHI-PROJECT-18K06771
[Presentation] 超臨界抽出-クロマトグラフィー/質量分析システムを用いた血中タクロリムス濃度測定方法の開発と応用2019
- Author(s)
  西村亜佐子、福島恵造、杉岡信幸、羽森真美、芝田信人
- Organizer
  第140年会日本薬学会
- Data Source
  KAKENHI-PROJECT-19K07180
[Presentation] 強制利尿法の用量が抗がん剤cisplatinの薬物動態および腎障害軽減作用に及ぼす影響.2017
- Author(s)
  岡田章, 大江裕之, 平崎実花, 中西真那, 藤田まい, 福島恵造, 杉岡信幸.
- Organizer
  第137年会日本薬学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K18941
[Presentation] 薬物体内動態における酸化ストレスの影響2014
- Author(s)
  中村有里, 大西優里, 岡田章, 福島恵造, 杉岡信幸.
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-23590211
[Presentation] TPN誘発性消化管萎縮におけるバンコマイシンの吸収動態変動2014
- Author(s)
  林頼子, 岡田章, 中本賀寿夫, 福島恵造, 徳山尚吾, 杉岡信幸.
- Organizer
  日本薬学会
- Place of Presentation
  熊本市総合体育館
- Data Source
  KAKENHI-PROJECT-24790178
[Presentation] 酸化ストレス病態下におけるシクロスポリンの血球移行率の変動2013
- Author(s)
  宮崎綾, 石野愛弓, 大西優里, 国府孝敏, 牛込秀隆, 吉村了勇, 福島恵造, 杉岡信幸
- Organizer
  第23回日本医療薬学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590211
[Presentation] 長期中心静脈栄養施行時における薬物療法の動態学的アセスメント2013
- Author(s)
  福島恵造, 三木隆弘, 岡田章, 中本賀寿夫, 小山光, 西村亜佐子, 芝田信人, 徳山尚吾, 杉岡信幸.
- Organizer
  日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学
- Data Source
  KAKENHI-PROJECT-24790178
[Presentation] TPN誘導性消化管萎縮時における薬物吸収動態変動2013
- Author(s)
  福島恵造、三木隆弘、山崎彩加、小山光、中本賀寿夫、徳山尚吾、杉岡信幸
- Organizer
  日本薬学会第１３３年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24790178
[Presentation] An exploratory study of pharmacokinetics in rats with intestinal atrophy induced by long-term total parenteral nutrition2012
- Author(s)
  Miki Takahiro, Keizo Fukushima, Ayaka Yamazaki, Hikaru Koyama, Kazuo Nakamoto, Shogo Tokuyama, Nobuyuki Sugioka
- Organizer
  27th JSSX Annual Meeting in Chiba (日本薬物動態学会　第２７回年回　千葉)
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-24790178

1. SUGIOKA Nobuyuki (40418934)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. USHIGOME Hidetaka (90405283)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 芝田信人 (60319449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

FUKUSHIMA Keizo 福島 恵造

福島 恵造 フクシマ ケイゾウ

Research Projects

Research Products

Co-Researchers

脂肪乳剤個別化投与速度設計の臨床実装を目的とした多施設共同研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

造血幹細胞移植における赤血球数変動を考慮したタクロリムスの全血中濃度再評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Prediction of cisplatin-induced nephrotoxicity in multicycle and exploration of risk factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pharmakokinetic-pharmacodynamic analysis of cisplatin with hydration and mannitol diuresisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pharmacokinetic assessment of intestinal atrophy induced by long-term parenteral nutritionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of pharmacokinetic change by lipid-, protein-oxidation and glycation, and its clinical application

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comparison of cisplatin-induced nephrotoxicity between single-dose and split-dose administration to rats2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Population pharmacokinetics of tacrolimus in umbilical cord blood transplant patients focusing on the variation in red blood cell counts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pharmacokinetic-Pharmacodynamic Analysis of Cisplatin with Hydration and Mannitol Diuresis: The Contribution of Urine Cisplatin Concentration to Nephrotoxicity.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Population Pharmacokinetic-Toxicodynamic Modeling and Simulation of Cisplatin-Induced Acute Renal Injury in Rats: Effect of Dosing Rate on Nephrotoxicity.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Intestinal Atrophy and Hepatic Impairment Induced by Parenteral Nutrition on Drug Absorption and Disposition in Rats.2013

Author(s)

Journal Title

Data Source

[Journal Article] Effects of obesity induced by high-fat diet on the pharmacokinetics of cyclosporine A in rats.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of obesity induced by high-fat diet on the pharmacokinetics of cyclosporine A in rats2011

Author(s)

Journal Title

Data Source

[Presentation] タクロリムスの全血/血漿中濃度比モデルのin vitro-in vivo外挿性の比較2023

Author(s)

Organizer

Data Source

[Presentation] 糖尿病モデルラットにおけるタクロリムスの脳移行性評価2023

Author(s)

FUKUSHIMA Keizo 福島恵造

福島恵造フクシマケイゾウ