Kawahata Hirohisa 川畑浩久

… Alternative Names

川畑浩久カワハタヒロヒサ

KAWAHATA Hirohisa 川畑浩久

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Researcher Number	30454680
Other IDs
Affiliation (Current)	2025: 森ノ宮医療大学, 医療技術学部, 教授
Affiliation (based on the past Project Information) *help	2024 – 2025: 森ノ宮医療大学, 医療技術学部, 教授 2018 – 2021: 森ノ宮医療大学, 保健医療学部, 教授 2015 – 2016: 森ノ宮医療大学, 保健医療学部, 教授 2013 – 2014: 森ノ宮医療大学, 保健医療学部, 准教授 2010 – 2014: 森ノ宮医療大学, 保健医療学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related / General internal medicine (including Psychosomatic medicine) Except Principal Investigator General internal medicine (including Psychosomatic medicine) / Basic Section 59010:Rehabilitation science-related / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator HIF1-α / HIF-1 / 線維化 / 関節拘縮 / 変形性関節症 / レニン・アンジオテンシン系 / 滑膜線維化 / アンギオテンシン II / NF-kB / HIF-1α … More / アンギオテンシンII / レニン・アンギオテンシン系 / アンギオテンシンII （AngII） / レニン・アンギオテンシン（RA）系 / Ang II 1型受容体(AT1R) / アンギオテンシンII (AngII) / レニン・アンギオテンシン(RA)系 / 滑膜組織 / HIF1α / ＣＴＧＦ / HIF / VEGF / CTGF / デコイ核酸医薬 / 滑膜 … More Except Principal Investigator 軟骨細胞 / レニンーアンジオテンシン系 / 運動療法 / 膝蓋下脂肪体 / 低酸素 / 線維化 / 変形性膝関節症 / アンジョテンシン受容体拮抗薬 / アンジオテンシン受容体拮抗薬 / 軟骨代謝 / アポトーシス / 軟骨変性 / 軟骨細胞代謝 / 変形性関節症 / 高血圧 / アンジオテンシン受容体拮抗剤 / アンジオテンシンII / 老年医学 / 骨折修復 / 骨芽細胞 / ARB / RA系 / アンジオテンシンII受容体拮抗薬 / 骨リモデリング / 骨粗鬆症 / サイトカイン / NFkB / 転写因子 / 炎症 / 東洋医学 / 内科学一般 / マクロファージ / 炎症性サイトカイン / 創傷治癒 / 筋肉再生 / 炎症性腸疾患 / 鍼灸刺激 / 東洋医療 Less

RA系による滑膜線維化メカニズムの解明：関節疾患と高血圧の分子相関メカニズムPrincipal Investigator
- Principal Investigator
  
  川畑浩久
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Morinomiya University of Medical Sciences
Development of the prevention exercise of osteoarthritis of the knee -focused on the hypoxia and fibrosis of the infrapatella fat pad-
- Principal Investigator
  
  工藤慎太郎
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Morinomiya University of Medical Sciences
Role of the RA system in disuse joint contracture: a new strategy to maintain ADLs in the elderlyPrincipal Investigator
- Principal Investigator
  
  Kawahata Hirohisa
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Morinomiya University of Medical Sciences
Angiotensin II Modulates Hypertrophic Differentiation and Apoptosis of Chondrocytes: Relationship of hypertension to Osteoarthrosis
- Principal Investigator
  
  Aoki Motokuni
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Elucidation of the molecular mechanisms that the axis of the HIF-1 in the joint contracture: the development of new molecular therapeutic formulationPrincipal Investigator
- Principal Investigator
  
  KAWAHATA Hirohisa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Role of RAS in bone remodeling and protective effect of ARB on bone density
- Principal Investigator
  
  AOKI Motokuni
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences
Effect of acupuncture on the molecular mechanism of inflammation via transcription factor, NFkB.
- Principal Investigator
  
  MATSUKUMA Hideaki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Morinomiya University of Medical Sciences

All 2021 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse2015
- Author(s)
  Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
- Journal Title
  
  Hypertension Research
  
  Volume: 38(6) Issue: 6 Pages: 382-393
- DOI
  10.1038/hr.2015.18
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460928
[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.2015
- Author(s)
  Kawahata H, Sotobayashi D, Aoki M, Shimizu H, Nakagami H, Ogihara T, Morishita R.
- Journal Title
  
  Ｈｙｐｅｒｔｅｎｓｉｏｎ　Ｒｅｓｅａｒｃｈ
  
  Volume: 19
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460928
[Journal Article] Anti-inflammatory effect of electro-acupuncture via rduction in clonic pristalsis in a mouse model of inflammatory bowel disease.2013
- Author(s)
  Yutani T, Kawahata H, Sotobayashi D, Kawanami H, Matsukuma H, Aoki M.
- Journal Title
  
  Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry.
  
  Volume: 13(2) Issue: 2 Pages: 122-131
- DOI
  10.2174/1871522211313020006
- Data Source
  KAKENHI-PROJECT-22590670
[Journal Article] 関節拘縮における滑膜の分子生物学的変化とLIPUSによる治療介入の検討2012
- Author(s)
  外林大輔,川畑浩久,吉川徹,穴田夏希,細田明菜,根來信也,青木元邦
- Journal Title
  
  兵庫学術誌
  
  Volume: 38号 Pages: 87-94
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 変形性膝関節症における膝蓋下脂肪体の線維化と低酸素状態の関連性2021
- Author(s)
  北川崇、平川佳祐、北野雅之、川畑浩久、工藤慎太郎
- Organizer
  第4回日本整形内科学研究会学術集会/第2回日本ファシア会議
- Data Source
  KAKENHI-PROJECT-18K07485
[Presentation] Relationship between Hypoxia and progression of fibrosis in infrapatellar pat pad with knee osteoarthritis.2021
- Author(s)
  Kitagawa T, Kawahata H, Tsusumi M, Kudo S
- Organizer
  16th Congress of the EACA (European Association of Clinical Anatomy
- Data Source
  KAKENHI-PROJECT-18K07485
[Presentation] Effect of angiotensin II on differentiation and apoptosis of chondrocytes in cartilage formation in the process of fracture healing2015
- Author(s)
  26.Hirohisa Kawahata, Motokuni Aoki, Ryuichi Morishita, Toshio Ogihara
- Organizer
  11th Asia Pacific Congress of Hypertension
- Place of Presentation
  Bali, Indonesia
- Year and Date
  2015-06-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460928
[Presentation] レニンーアンジオテンシン系が骨形成系・軟骨細胞分化・骨折修復過程に及ぼす影響についての検討2014
- Author(s)
  川畑浩久、青木元邦
- Organizer
  日本抗加齢医学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-06
- Data Source
  KAKENHI-PROJECT-26460928
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響-炎症性腸疾患への補完医療確立に向けて-2013
- Author(s)
  湯谷達、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] 関節拘縮における関節内病変についての組織学的・分子生物学的検討2013
- Author(s)
  川畑浩久、青木元邦、森下竜一、荻原俊男
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 灸刺激が創傷治癒過程に与える影響2013
- Author(s)
  川波博、湯谷達、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  福岡
- Year and Date
  2013-06-09
- Data Source
  KAKENHI-PROJECT-22590670
[Presentation] レニン―アンジオテンシン系が骨折修復過程に与える影響についての検討2013
- Author(s)
  青木元邦,川畑浩久,森下竜,荻原俊男
- Organizer
  第55回日本老年医学会
- Place of Presentation
  大阪国際会議場．大阪
- Data Source
  KAKENHI-PROJECT-23590902
[Presentation] レニンーアンジオテンシン系が骨折修復過程に与える影響についての検討2013
- Author(s)
  青木元邦、川畑浩久、荻原俊男
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2013-06-06
- Data Source
  KAKENHI-PROJECT-23590902
[Presentation] 関節拘縮における滑膜の分子生物学的変化とLIPUSによる治療介入の検討2012
- Author(s)
  川畑浩久,外林大輔,根來信也,葉山直史,吉川徹
- Organizer
  第21回日本柔道整復接骨医学会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 関節拘縮の進展メカニズムに関する検討2012
- Author(s)
  青木元邦,外林大輔,川畑浩久
- Organizer
  第12回日本抗加齢医学会総会
- Place of Presentation
  神奈川パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24590906
[Presentation] 腸炎モデルマウスに対する鍼刺激の影響-炎症性腸疾患への補完医療確立に向けて-2012
- Author(s)
  湯谷達、浅野真里絵、川畑浩久、青木元邦
- Organizer
  全日本鍼灸学会学術大会
- Place of Presentation
  三重
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22590670

1. AOKI Motokuni (00346214)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. HIRONORI Nakagami (20325369)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. OGIHARA Toshio (60107042)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. MATSUKUMA Hideaki (70518638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 工藤慎太郎 (70737915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 堤真大 (10821853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 河西謙吾 (00989717)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 角田晃啓 (80557314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kawahata Hirohisa 川畑 浩久

川畑 浩久 カワハタ ヒロヒサ

KAWAHATA Hirohisa 川畑 浩久

Research Projects

Research Products

Co-Researchers

RA系による滑膜線維化メカニズムの解明：関節疾患と高血圧の分子相関メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the prevention exercise of osteoarthritis of the knee -focused on the hypoxia and fibrosis of the infrapatella fat pad-

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of the RA system in disuse joint contracture: a new strategy to maintain ADLs in the elderlyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Angiotensin II Modulates Hypertrophic Differentiation and Apoptosis of Chondrocytes: Relationship of hypertension to Osteoarthrosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanisms that the axis of the HIF-1 in the joint contracture: the development of new molecular therapeutic formulationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of RAS in bone remodeling and protective effect of ARB on bone density

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of acupuncture on the molecular mechanism of inflammation via transcription factor, NFkB.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Continuous infusion of angiotensin II modulates hypertrophic differentiation and apoptosis of chondrocytes in cartilage formation in a fracture model mouse.2015

Author(s)

Journal Title

Data Source

[Journal Article] Anti-inflammatory effect of electro-acupuncture via rduction in clonic pristalsis in a mouse model of inflammatory bowel disease.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 関節拘縮における滑膜の分子生物学的変化とLIPUSによる治療介入の検討2012

Author(s)

Journal Title

Data Source

[Presentation] 変形性膝関節症における膝蓋下脂肪体の線維化と低酸素状態の関連性2021

Author(s)

Organizer

Data Source

[Presentation] Relationship between Hypoxia and progression of fibrosis in infrapatellar pat pad with knee osteoarthritis.2021

Author(s)

Organizer

Data Source

[Presentation] Effect of angiotensin II on differentiation and apoptosis of chondrocytes in cartilage formation in the process of fracture healing2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Kawahata Hirohisa 川畑浩久

川畑浩久カワハタヒロヒサ

KAWAHATA Hirohisa 川畑浩久