Tanaka Akito 田中明人

… Alternative Names

TANAKA AKITO 田中明人

AKITO Tanaka 田中明人

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Researcher Number	30454789
Affiliation (Current)	2023: 兵庫医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021: 兵庫医療大学, 薬学部, 教授 2011 – 2019: 兵庫医療大学, 薬学部, 教授 2007 – 2009: Hyogo University of Health Sciences, 薬学部, 教授
Review Section/Research Field	Principal Investigator Drug development chemistry / Living organism molecular science Except Principal Investigator Basic Section 37030:Chemical biology-related / Drug development chemistry
Keywords	Principal Investigator 前立腺がん / 前立腺癌 / 創薬化学 / PCA-1 / 抗がん剤 / 光反応 / 生理活性物質 / ターゲット探索 / アフィニティ樹脂 / 創薬 … More / 癌 / PCA-1阻害剤 / 経口剤 / xenograftモデル / 代謝安定性 / 創薬ターゲット / 活性発現の分子機構 … More Except Principal Investigator Rab / アフィニティ樹脂 / アレルギー / 前立腺 / Cisplatin / 中皮腫 / 前立腺癌 / ＡＬＫＢＨ３ / ＰＣＡ－１ / MESO-4 / 悪性中皮腫 / 併用効果 / Docetaxel / 前立腺がん / 抗がん剤 / ALKBH3 / PCA-1 Less

アフィニティ技術により同定した新規標的分子Rabを制御する抗アレルギー薬の創製
- Principal Investigator
  
  所美雪 (馬渕美雪)
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37030:Chemical biology-related
- Research Institution
  Hyogo University of Health Sciences
Investigation of novel oral/ intraveneous PCA-1 inhibitors of for cancerPrincipal Investigator
- Principal Investigator
  
  Tanaka Akito
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences
Drug discovery research for clinical application of PCA-1 inhibitors
- Principal Investigator
  
  TOKORO(MABUCHI) Miyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences
Design and synthesis of novel PCA-1 inhibitor for clinical anticancer drugPrincipal Investigator
- Principal Investigator
  
  TANAKA AKITO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences
Development of versatile method for identification of the target protein using affinity resins with photo-labile linkerPrincipal Investigator
- Principal Investigator
  
  TANAKA AKITO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hyogo University of Health Sciences
Development of novel photo-cleavable linker for the target identification of bio-active compound using affinity resinsPrincipal Investigator
- Principal Investigator
  
  AKITO Tanaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Hyogo University of Health Sciences

All 2018 2017 2015 2014 2012 2011 2009 2008 Other

All Journal Article Presentation

[Journal Article] Novel Metabolically Stable PCA-1/ALKBH3 Inhibitor Has Potent Antiproliferative Effects on DU145 Cells In Vivo.2018
- Author(s)
  Ueda M, Shimizu T, Mabuchi M, Horiike K, Kitae K, Hase H, Ueda Y, Tsujikawa K, Tanaka A
- Journal Title
  
  Anticancer Res.
  
  Volume: 38 Issue: 1 Pages: 211-218
- DOI
  10.21873/anticanres.12210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07186, KAKENHI-PROJECT-15K08036
[Journal Article] Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model2017
- Author(s)
  MIYUKI MABUCHI, MASAHIRO UEDA, YURI YOSHIDA, KOTA HORIIKE, KENTA YAMAOKA, SYUHEI NAKAO, TADASHI SHIMIZU, YUKO UEDA, KAZUTAKE TSUJIKAWA, AKITO TANAKA
- Journal Title
  
  anticancer research
  
  Volume: 37 Issue: 4 Pages: 1665-1676
- DOI
  10.21873/anticanres.11496
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460164, KAKENHI-PROJECT-15K08036, KAKENHI-PROJECT-16K07186
[Journal Article] 3.Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK5062015
- Author(s)
  Mabuchi M, Shimizu T, Ueda M, Mitamura K, Ikegawa S, Tanaka A.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 25 Issue: 14 Pages: 2788-2792
- DOI
  10.1016/j.bmcl.2015.05.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460211, KAKENHI-PROJECT-15K08036
[Journal Article] 創薬シーズ探索の魅力2012
- Author(s)
  田中明人
- Journal Title
  
  化学工業
  
  Volume: 63 Pages: 249-257
- Data Source
  KAKENHI-PROJECT-23510269
[Journal Article] 21世紀の化学の夢2011
- Author(s)
  田中明人
- Journal Title
  
  学術の動向
  
  Volume: 5 Pages: 58-61
- Data Source
  KAKENHI-PROJECT-23510269
[Journal Article] Improvement of monolithic solid material byutilization of spacer for identification of the target using affinity resins.2009
- Author(s)
  E. Iwaoka, T. Mori, T. Shimizu, K. Hosoya, A. Tanaka
- Journal Title
  
  Med.Chem.Lett 19
  
  Pages: 1469-1472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599025
[Journal Article] Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins2009
- Author(s)
  Emiko Iwaoka, Tomoko Mori, Tadashi Shimizu, Ken Hosoya, Akito Tanaka
- Journal Title
  
  Bioorg. Med. Chem. Lett. 19
  
  Pages: 1469-1472
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599025
[Journal Article] Properties of flaky affinity resin with co-continuous structure.2008
- Author(s)
  T. Mori, A. Tanaka, T. Kubo, K. Kaya, M. Sakamoto, K. Hosoya
- Journal Title
  
  Bioorg. Med. Chem. 16
  
  Pages: 1983-1991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599025
[Journal Article] Properties of flaky affinity resin with co-continuous structure2008
- Author(s)
  T. Mori, A. Tanaka, T. kubo, K. Kaya, M. Sakamoto, K. Hosoya
- Journal Title
  
  Bioorg.Med.Chem 16
  
  Pages: 1983-1991
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19599025
[Presentation] 前立腺癌治療薬を目指したprostate cancer antigen-1(PCA-1/ALKBH3)阻害剤HUHS015のデザインと合成2014
- Author(s)
  中尾周平,　清水忠,　馬渕美雪,　上田昌宏,　上田裕子,　辻川和丈,　田中明人
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460164
[Presentation] 前立腺癌治療薬を目指した創薬研究：新規PCA-1阻害剤HUHS015の塩検討による体内動態改善およびXenograft model薬効向上研究2014
- Author(s)
  馬渕美雪, 清水忠, 笹川由香, 中尾周平, 上田昌宏, 上田裕子,辻川和丈,　田中明人
- Organizer
  第32回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26460164
[Presentation] アフィニティ樹脂用固相担体AquaFirmusTM 開発研究１：既存固相担体（Toyopearl、Affigel、SCNEGDE gel）との比較研究2012
- Author(s)
  馬渕美雪、清水忠、竹内由生子、上田昌宏、中尾周平、伊藤嘉洋、西崎知之、磯貝隆夫、田中明人
- Organizer
  第7回ケミカルバイオロジー学会
- Place of Presentation
  京都大学百周年記念ホール（京都）
- Data Source
  KAKENHI-PROJECT-23510269
[Presentation] AffiGelR並みに非特異的蛋白吸着が少ないメタクリレート系固相担体"AquaFirmus"の開発2009
- Author(s)
  馬渕美雪、岩岡恵美子2、市山高明、高橋晃樹、清水忠、西崎知之、磯貝隆夫、田中明人
- Organizer
  第4回ケミカルバイオロジー学会
- Place of Presentation
  神戸市産業振興センター
- Year and Date
  2009-05-18
- Data Source
  KAKENHI-PROJECT-19599025
[Presentation] AffiGeIR並みに非特異的蛋白吸着が少ないメタクリレート系固相担体“AquaFirmus"の開発
- Author(s)
  馬渕美雪、岩岡恵美子、市山高明、高橋晃樹、清水忠、西崎知之、磯貝隆夫、田中明人
- Organizer
  第4回ケミカルバイオロジー学会
- Place of Presentation
  神戸市産業振興センター(神戸)
- Data Source
  KAKENHI-PROJECT-19599025

1. TOKORO MIYUKI (60714897)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. TSUJIKAWA KAZUTAKE (10207376)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. INOUE TAKASHI (20263204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山下政克 (00311605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. SHIMIZU Tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 三田村邦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Akito 田中 明人

TANAKA AKITO 田中 明人

AKITO Tanaka 田中 明人

Research Projects

Research Products

Co-Researchers

アフィニティ技術により同定した新規標的分子Rabを制御する抗アレルギー薬の創製

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of novel oral/ intraveneous PCA-1 inhibitors of for cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drug discovery research for clinical application of PCA-1 inhibitors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Design and synthesis of novel PCA-1 inhibitor for clinical anticancer drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of versatile method for identification of the target protein using affinity resins with photo-labile linkerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel photo-cleavable linker for the target identification of bio-active compound using affinity resinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Novel Metabolically Stable PCA-1/ALKBH3 Inhibitor Has Potent Antiproliferative Effects on DU145 Cells In Vivo.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 3.Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK5062015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 創薬シーズ探索の魅力2012

Author(s)

Journal Title

Data Source

[Journal Article] 21世紀の化学の夢2011

Author(s)

Journal Title

Data Source

[Journal Article] Improvement of monolithic solid material byutilization of spacer for identification of the target using affinity resins.2009

Author(s)

Journal Title

Data Source

[Journal Article] Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins2009

Author(s)

Journal Title

Data Source

[Journal Article] Properties of flaky affinity resin with co-continuous structure.2008

Author(s)

Journal Title

Data Source

[Journal Article] Properties of flaky affinity resin with co-continuous structure2008

Author(s)

Journal Title

Tanaka Akito 田中明人

TANAKA AKITO 田中明人

AKITO Tanaka 田中明人