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Tanaka Akito  田中 明人

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TANAKA AKITO  田中 明人

AKITO Tanaka  田中 明人

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Researcher Number 30454789
Affiliation (Current) 2022: 兵庫医科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2011 – 2019: 兵庫医療大学, 薬学部, 教授
2007 – 2009: Hyogo University of Health Sciences, 薬学部, 教授
Review Section/Research Field
Principal Investigator
Drug development chemistry / Living organism molecular science
Except Principal Investigator
Drug development chemistry / Basic Section 37030:Chemical biology-related
Keywords
Principal Investigator
アフィニティ樹脂 / ターゲット探索 / 生理活性物質 / 光反応 / 抗がん剤 / PCA-1 / 創薬化学 / 前立腺癌 / 前立腺がん / 活性発現の分子機構 … More / 創薬ターゲット / 代謝安定性 / xenograftモデル / 経口剤 / PCA-1阻害剤 / 癌 / 創薬 … More
Except Principal Investigator
PCA-1 / ALKBH3 / 抗がん剤 / 前立腺がん / Docetaxel / 併用効果 / 悪性中皮腫 / MESO-4 / PCA-1 / ALKBH3 / 前立腺癌 / 中皮腫 / Cisplatin / 前立腺 / アレルギー / アフィニティ樹脂 / Rab Less
  • Research Projects

    (6 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (6 People)
  •  アフィニティ技術により同定した新規標的分子Rabを制御する抗アレルギー薬の創製

    • Principal Investigator
      所 美雪 (馬渕美雪)
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 37030:Chemical biology-related
    • Research Institution
      Hyogo University of Health Sciences
  •  新規抗がん剤を目指した経口/点滴投与で有効なPCA-1阻害剤探索研究Principal Investigator

    • Principal Investigator
      田中 明人
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hyogo University of Health Sciences
  •  Drug discovery research for clinical application of PCA-1 inhibitors

    • Principal Investigator
      TOKORO(MABUCHI) Miyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hyogo University of Health Sciences
  •  Design and synthesis of novel PCA-1 inhibitor for clinical anticancer drugPrincipal Investigator

    • Principal Investigator
      TANAKA AKITO
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hyogo University of Health Sciences
  •  Development of versatile method for identification of the target protein using affinity resins with photo-labile linkerPrincipal Investigator

    • Principal Investigator
      TANAKA AKITO
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Living organism molecular science
    • Research Institution
      Hyogo University of Health Sciences
  •  Development of novel photo-cleavable linker for the target identification of bio-active compound using affinity resinsPrincipal Investigator

    • Principal Investigator
      AKITO Tanaka
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Hyogo University of Health Sciences

All 2018 2017 2015 2014 2012 2011 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Novel Metabolically Stable PCA-1/ALKBH3 Inhibitor Has Potent Antiproliferative Effects on DU145 Cells In Vivo.2018

    • Author(s)
      Ueda M, Shimizu T, Mabuchi M, Horiike K, Kitae K, Hase H, Ueda Y, Tsujikawa K, Tanaka A
    • Journal Title

      Anticancer Res

      Volume: 38 Pages: 211-218

    • DOI

      10.21873/anticanres.12210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07186, KAKENHI-PROJECT-15K08036
  • [Journal Article] Systematic Trial for Evaluating Docetaxel in a Human Prostate Cancer Cell DU145 Xenograft Model.2017

    • Author(s)
      MIYUKI MABUCHI, MASAHIRO UEDA, YURI YOSHIDA, KOTA HORIIKE, KENTA YAMAOKA, SYUHEI NAKAO, TADASHI SHIMIZU, YUKO UEDA, KAZUTAKE TSUJIKAWA, AKITO TANAKA
    • Journal Title

      Anticancer Res.

      Volume: 37 Pages: 1665-1676

    • DOI

      10.21873/anticanres.11496

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460164, KAKENHI-PROJECT-15K08036, KAKENHI-PROJECT-16K07186
  • [Journal Article] Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK506.2015

    • Author(s)
      Mabuchi M, Shimizu T, Ueda M, Mitamura K, Ikegawa S, Tanaka A.
    • Journal Title

      Bioorg Med Chem Lett.

      Volume: 25 Pages: 2788-2792

    • DOI

      10.1016/j.bmcl.2015.05.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460211, KAKENHI-PROJECT-15K08036
  • [Journal Article] 創薬シーズ探索の魅力2012

    • Author(s)
      田中明人
    • Journal Title

      化学工業

      Volume: 63 Pages: 249-257

    • Data Source
      KAKENHI-PROJECT-23510269
  • [Journal Article] 21世紀の化学の夢2011

    • Author(s)
      田中明人
    • Journal Title

      学術の動向

      Volume: 5 Pages: 58-61

    • Data Source
      KAKENHI-PROJECT-23510269
  • [Journal Article] Improvement of monolithic solid material byutilization of spacer for identification of the target using affinity resins.2009

    • Author(s)
      E. Iwaoka, T. Mori, T. Shimizu, K. Hosoya, A. Tanaka
    • Journal Title

      Med.Chem.Lett 19

      Pages: 1469-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599025
  • [Journal Article] Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins2009

    • Author(s)
      Emiko Iwaoka, Tomoko Mori, Tadashi Shimizu, Ken Hosoya, Akito Tanaka
    • Journal Title

      Bioorg. Med. Chem. Lett. 19

      Pages: 1469-1472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599025
  • [Journal Article] Properties of flaky affinity resin with co-continuous structure.2008

    • Author(s)
      T. Mori, A. Tanaka, T. Kubo, K. Kaya, M. Sakamoto, K. Hosoya
    • Journal Title

      Bioorg. Med. Chem. 16

      Pages: 1983-1991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599025
  • [Journal Article] Properties of flaky affinity resin with co-continuous structure2008

    • Author(s)
      T. Mori, A. Tanaka, T. kubo, K. Kaya, M. Sakamoto, K. Hosoya
    • Journal Title

      Bioorg.Med.Chem 16

      Pages: 1983-1991

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19599025
  • [Presentation] 前立腺癌治療薬を目指したprostate cancer antigen-1(PCA-1/ALKBH3)阻害剤HUHS015のデザインと合成2014

    • Author(s)
      中尾周平, 清水忠, 馬渕美雪, 上田昌宏, 上田裕子, 辻川和丈, 田中明人
    • Organizer
      第32回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-26460164
  • [Presentation] 前立腺癌治療薬を目指した創薬研究:新規PCA-1阻害剤HUHS015の塩検討による体内動態改善およびXenograft model薬効向上研究2014

    • Author(s)
      馬渕美雪, 清水忠, 笹川由香, 中尾周平, 上田昌宏, 上田裕子,辻川和丈, 田中明人
    • Organizer
      第32回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2014-11-26
    • Data Source
      KAKENHI-PROJECT-26460164
  • [Presentation] アフィニティ樹脂用固相担体AquaFirmusTM 開発研究1:既存固相担体(Toyopearl、Affigel、SCNEGDE gel)との比較研究2012

    • Author(s)
      馬渕美雪 、清水忠、竹内由生子、上田昌宏、中尾周平、伊藤嘉洋、西崎知之、磯貝隆夫、田中明人
    • Organizer
      第7回ケミカルバイオロジー学会
    • Place of Presentation
      京都大学百周年記念ホール(京都)
    • Data Source
      KAKENHI-PROJECT-23510269
  • [Presentation] AffiGelR並みに非特異的蛋白吸着が少ないメタクリレート系固相担体"AquaFirmus"の開発2009

    • Author(s)
      馬渕美雪、岩岡恵美子2、市山高明、高橋晃樹、清水忠、西崎知之、磯貝隆夫、田中明人
    • Organizer
      第4回ケミカルバイオロジー学会
    • Place of Presentation
      神戸市産業振興センター
    • Year and Date
      2009-05-18
    • Data Source
      KAKENHI-PROJECT-19599025
  • [Presentation] AffiGeIR並みに非特異的蛋白吸着が少ないメタクリレート系固相担体“AquaFirmus"の開発

    • Author(s)
      馬渕美雪、岩岡恵美子、市山高明、高橋晃樹、清水忠、西崎知之、磯貝隆夫、田中明人
    • Organizer
      第4回ケミカルバイオロジー学会
    • Place of Presentation
      神戸市産業振興センター(神戸)
    • Data Source
      KAKENHI-PROJECT-19599025
  • 1.  TOKORO MIYUKI (60714897)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  TSUJIKAWA KAZUTAKE (10207376)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  INOUE TAKASHI (20263204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  山下 政克 (00311605)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SHIMIZU Tadashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  三田村 邦子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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