Sakashita Tomohiro 坂下智博

Researcher Number	30455654
Other IDs
Affiliation (based on the past Project Information) *help	2016: 北海道大学, 医学研究科, 助教 2014 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator サイクリンD1 / 頭頸部外科学 / cyclin D1標的sgRNA / cyclin D1標的RNA / 遺伝子標的治療 / cyclin D1 / 頭頸部癌

The gene tartgeting therapy with the use of sgRNA targeting cyclin D1 for head and neck cancerPrincipal Investigator
- Principal Investigator
  
  Sakashita Tomohiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Hokkaido University

All 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Comparison of hearing outcomes after treatment for early-stage external auditory canal cancer.2016
- Author(s)
  Morita S, Nakamaru Y, Homma A, Sakashita T, Hatakeyama H, Masuya M, Fukuda S.
- Journal Title
  
  Head Neck.
  
  Volume: 38 Suppl 1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Journal Article] The Outcomes of Surgery and Chemoradiotherapy for Temporal Bone Cancer.2016
- Author(s)
  Morita S, Homma A, Nakamaru Y, Sakashita T, Hatakeyama H, Kano S, Fukuda A, Fukuda S.
- Journal Title
  
  Otol Neurotol.
  
  Volume: 37 Pages: 1174-1182
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Journal Article] Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis.2016
- Author(s)
  Suzuki T, Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Suzuki F, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume: 273 Pages: 3331-3336
- NAID
  120006347189
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Journal Article] A retrospective study of G-tube use in Japanese patients treated with concurrent chemoradiotherapy for hypopharyngeal cancer.2016
- Author(s)
  Homma A, Hatakeyama H, Mizumachi T, Kano S, Sakashita T, Kuramoto R, Nakamaru Y, Onimaru R, Tsuchiya K, Yoshida D, Yasuda K, Shirato H, Fukuda S.
- Journal Title
  
  Plos One
  
  Volume: 11 Issue: 8 Pages: e0161734-e0161734
- DOI
  10.1371/journal.pone.0161734
- NAID
  120005866840
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462591, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma.2016
- Author(s)
  Tsushima N, Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Kakizaki T, Suzuki T, Fukuda S.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume: 273 Pages: 3987-3992
- NAID
  120006360053
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Journal Article] Clinical outcomes of weekly cisplatin chemoradiotherapy for patients with pyriform sinus cancer.2015
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Furusawa J, Kano S, Mizumachi T, Iizuka S, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.
- Journal Title
  
  Int J Clin Oncol.
  
  Volume: 20 Issue: 6 Pages: 1081-1085
- DOI
  10.1007/s10147-015-0821-8
- NAID
  120005890011
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] Comparison of acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas: A single-institution retrospective study in Japan.2015
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Furusawa J, Kano S, Mizumachi T, Iizuka S, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Fukuda S.
- Journal Title
  
  Acta Otolaryngologica
  
  Volume: 135 Issue: 8 Pages: 853-858
- DOI
  10.3109/00016489.2015.1030772
- NAID
  120005820705
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] The role of initial neck dissection for patients with node-positive oropharyngeal squamous cell carcinomas2014
- Author(s)
  T. Sakashita, A. Homma, R. Hayashi, K. Kawabata, K. Yoshino, S. Iwae, Y. Hasegawa, K. Nibu, T. Kato, K. Shiga, K. Matsuura, N. Monden, M. Fuji
- Journal Title
  
  Oral Oncology
  
  Volume: 40 Issue: 7 Pages: 211-215
- DOI
  10.1016/j.oraloncology.2014.03.003
- NAID
  120005464719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592521, KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-24592613, KAKENHI-PROJECT-26861352
[Journal Article] Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy.2014
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Kano S, Mizumachi T, Furusawa J, Yoshida D, Fujima N, Onimaru R, Tsuchiya K, Yasuda K, Shirato H, Suzuki F, Fukuda S.
- Journal Title
  
  Br J Oral Maxillofac Surg
  
  Volume: 52 Issue: 4 Pages: 323-328
- DOI
  10.1016/j.bjoms.2014.01.018
- NAID
  120005476154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Journal Article] The potential diagnostic role of the number of ultrasonographic characteristics for patients with thyroid nodules evaluated as bethesdaI-v.2014
- Author(s)
  Sakashita T, Homma A, Hatakeyama H, Mizumachi T, Kano S, Furusawa J, Iizuka S, Hoshino K, Hatanaka KC, Oba K, Fukuda S.
- Journal Title
  
  Front Oncol.
  
  Volume: 4 Pages: 261-261
- DOI
  10.3389/fonc.2014.00261
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592587, KAKENHI-PROJECT-26861352, KAKENHI-PROJECT-26861353
[Presentation] 舌癌N0症例における予防的頸部郭清術の役割と潜在的頸部転移陽性率に関する検討2016
- Author(s)
  坂下智博、本間明宏、対馬那由多、福田諭
- Organizer
  第29回口腔咽頭科学会
- Place of Presentation
  松江テルサ（島根県松江市）
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] The multi-institutional dose-finding trial of superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for patients with locally advanced maxillary sinus cancer (JCOG1212, RADPLAT-MSC)2016
- Author(s)
  Tomohiro Sakashita, Akihiro Homma, Rikiya Onimaru, Kazuto Matsuura, Hirotaka Shinomiya, Ryuichi Hayashi, Kiyoto Shiga, Hiroyuki Tachibana, Masato Fujii
- Organizer
  European society for medical oncology (ESMO) congress 2016
- Place of Presentation
  Copenhagen（Denmark）
- Year and Date
  2016-10-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] The role of cyclin D1 in surgical margins as a potential prognostic indicator.2015
- Author(s)
  Tomohiro Sakashita, Nobuhiko Oridate, Akihiro Homma, Hiromitsu Hatakeyama, , Satoshi Kano, Takatsugu Mizumachi, Satoshi Fukuda.
- Organizer
  4th Congress of Asian Society of Head and Neck Oncology/ 39th Annual Meeting of Japan Society for Head and Neck Cancer
- Place of Presentation
  Kobe International Conference Center(Kobe, Japan.)
- Year and Date
  2015-06-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] The different nature of mucositis between cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy in malignancies of the upper aerodigestive tracts.2015
- Author(s)
  Tomohiro Sakashita, Akihiro Homma, Hiromitsu Hatakeyama, Satoshi Kano, Takatsugu Mizumachi, Tomohiko Kakizaki, Nayuta Tsushima, Takayoshi Suzuki, Rikiya Onimaru, Kazuhiko Tsuchiya, Koichi Yasuda, Hiroki Shirato, and Satoshi Fukuda
- Organizer
  13th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery.
- Place of Presentation
  Hitotsubashi Hall,National Center of Science Building (Tokyo, Japan.)
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] Acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas.2015
- Author(s)
  Tomohiro Sakashita, Akihiro Homma, Hiromitsu Hatakeyama, Satoshi Kano, Takatsugu Mizumachi, Tomohiko Kakizaki, Nayuta Tsushima, Takayoshi Suzuki, Rikiya Onimaru, Kazuhiko Tsuchiya, Koichi Yasuda, Hiroki Shirato, and Satoshi Fukuda
- Organizer
  23rd Asia Pacific Cancer Conference
- Place of Presentation
  Grand Hyatt Hotel(Bali, Indonesia.)
- Year and Date
  2015-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] 術前細胞診にて悪性が確定しなかった甲状腺結節におけるエコー陽性所見の数と悪性リスクの関係について2014
- Author(s)
  4.坂下智博、本間明宏、畠山博充、水町貴諭、加納里志、古沢純、飯塚さとし、干野季美子、畑中佳奈子、福田諭
- Organizer
  第47回日本甲状腺外科学会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] 北海道大学における頭頸部癌治療の実際とセツキシマブ併用放射線治療の位置づけ2014
- Author(s)
  坂下智博
- Organizer
  弘前頭頸部癌セミナー
- Place of Presentation
  弘前大学医学部（青森県弘前市）
- Year and Date
  2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] 眼窩骨壁浸潤を伴う進行上顎洞癌における治療別生存率比較～眼窩内容温存全摘術の妥当性について～
- Author(s)
  坂下智博、林隆一、本間明宏、松浦一登、加藤健吾、川端一嘉、松塚崇、岩江信法、大上研二、藤井正人
- Organizer
  第38回日本頭頸部癌学会総会
- Place of Presentation
  東京ファッションタウンビル（東京都江東区）
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-26861352
[Presentation] 頸部転移を有する中咽頭扁平上皮癌における初回頸部郭清術の意義
- Author(s)
  3.坂下智博、本間明宏、林隆一、岩江信法、藤井正人
- Organizer
  第27回日本口腔咽頭科学会総会
- Place of Presentation
  ホテルライフォート札幌（北海道札幌市）
- Year and Date
  2014-09-11 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26861352

1. KATO Kengo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. HATAKEYAMA Hiromitsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 松浦一登

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 本間明宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Sakashita Tomohiro 坂下 智博

Research Projects

Research Products

Co-Researchers

The gene tartgeting therapy with the use of sgRNA targeting cyclin D1 for head and neck cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Comparison of hearing outcomes after treatment for early-stage external auditory canal cancer.2016

Author(s)

Journal Title

Data Source

[Journal Article] The Outcomes of Surgery and Chemoradiotherapy for Temporal Bone Cancer.2016

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A retrospective study of G-tube use in Japanese patients treated with concurrent chemoradiotherapy for hypopharyngeal cancer.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The role of prophylactic neck dissection and tumor thickness evaluation for patients with cN0 tongue squamous cell carcinoma.2016

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Clinical outcomes of weekly cisplatin chemoradiotherapy for patients with pyriform sinus cancer.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Comparison of acute toxicities associated with cetuximab-based bioradiotherapy and platinum-based chemoradiotherapy for head and neck squamous cell carcinomas: A single-institution retrospective study in Japan.2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The role of initial neck dissection for patients with node-positive oropharyngeal squamous cell carcinomas2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Salvage operations for patients with persistent or recurrent cancer of the maxillary sinus after superselective intra-arterial infusion of cisplatin with concurrent radiotherapy.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The potential diagnostic role of the number of ultrasonographic characteristics for patients with thyroid nodules evaluated as bethesdaI-v.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 舌癌N0症例における予防的頸部郭清術の役割と潜在的頸部転移陽性率に関する検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The multi-institutional dose-finding trial of superselective intra-arterial infusion of cisplatin and concomitant radiotherapy for patients with locally advanced maxillary sinus cancer (JCOG1212, RADPLAT-MSC)2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The role of cyclin D1 in surgical margins as a potential prognostic indicator.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Sakashita Tomohiro 坂下智博