ZHANG Erquan 張尓泉

Researcher Number	30456727
Affiliation (based on the past Project Information) *help	2016 – 2019: 三重大学, 医学系研究科, 助教 2011 – 2015: 三重大学, 医学(系)研究科(研究院), 助教 2014: 三重大学, 大学院医学系研究科, 助教 2009 – 2011: 三重大学, 大学院・医学系研究科, 助教
Review Section/Research Field	Principal Investigator Anesthesiology / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 生理学 / 組織 / 肺高血圧症 / pulmonary hypertension / 国際情報交流 / H2S / VILI / 硫化水素 / 人工呼吸器誘発肺傷害 Except Principal Investigator 一酸化窒素 … More / 肺高血圧 / モノクロタリン / 外科 / TRPV4 / イオンチャネル / ＴＲＰＶ / TRPV / 肺高血圧症 / uncoupled NOS / 低酸素 / Febuxostat / フェブキソスタット / キサンチンオキシダーゼ / スーパーオキシド / NaHS / 慢性低酸素 / 硫化水素ナトリウム / 硫化水素 / トロンボモジュリン Less

Analysis of TRPV channel in experimantal pulmonary hypertension and treatment
- Principal Investigator
  
  Maruyama Kazuo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Mie University
Treatment with NO-dependent activated nitrite in experimental pulmonary hypertensionPrincipal Investigator
- Principal Investigator
  
  Zhang Erquan
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Mie University
Role of superoxide in pulmonary hypertension and treatment with xanthine oxidase inhibition
- Principal Investigator
  
  Yokochi Ayumu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Mie University
pulmonary hypertension and hydrogen sulfate
- Principal Investigator
  
  MARUYAMA Kazuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Mie University
Effects of hydrogen sulfide on ventilator induced lung injuryPrincipal Investigator
- Principal Investigator
  
  ZHANG Erquan
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Mie University
Therapeutic target for pulmonary hypertension based on coagulative and inflammatory cascade analysis
- Principal Investigator
  
  MARUYAMA Kazuo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Mie University

All 2019 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] 呼吸管理　Q &　A　　　２７章　　NO吸入療法とは2013
- Author(s)
  丸山一男、張尓泉、丸山淳子
- Total Pages
  308
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-24592333
[Book] クリティカルケアにおける呼吸管理　　１．呼吸生理2013
- Author(s)
  丸山一男、張尓泉、横地　歩
- Total Pages
  276
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-24592333
[Book] 呼吸の生理.クリテイカルケアにおける呼吸管理.編集:氏家良人2013
- Author(s)
  丸山一男、張尓泉、横地歩
- Publisher
  克誠堂出版
- Data Source
  KAKENHI-PROJECT-23592283
[Book] PULMONARY　HYPERTENSION　　4. Nitric oxide in pathophysiology and treatment of pulmonary hypertension2013
- Author(s)
  Junko Maruyama, Yokochi A,　Zhang E, Sawada H,　Maruyama K.
- Total Pages
  233
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-24592333
[Book] Gas Biology Research in Clinical Practice2011
- Author(s)
  Maruyama K, Zhang K, Maruyama J
- Publisher
  KARGER, Basel
- Data Source
  KAKENHI-PROJECT-21592003
[Book] Gas Biology Research in Clinical Practice2011
- Author(s)
  Yoshikawa, et al. eds. Kazuo Maruyama, Erquan Zhang, Junko Maruayma
- Publisher
  Kargar Basel
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] Potential Contribution of Phenotypically Modulated Smooth Muscle Cells and Related Inflammation in the Development of Experimental Obstructive Pulmonary Vasculopathy in Rats.2015
- Author(s)
  Otsuki S, Sawada H, Yodoya N, Shinohara T, Kato T, Ohashi H, Zhang E, Imanaka-Yoshida K, Shimpo H, Maruyama K, Komada Y, Mitani Y.
- Journal Title
  
  PLoS One.
  
  Volume: 10 Issue: 2 Pages: 0118655-0118655
- DOI
  10.1371/journal.pone.0118655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591573, KAKENHI-PROJECT-24591574, KAKENHI-PROJECT-24592333, KAKENHI-PROJECT-24791057, KAKENHI-PROJECT-26461606, KAKENHI-PROJECT-15K09688
[Journal Article] Macitentan reverses early obstructive pulmonary vasculopathy in rats: early intervention in overcoming the survivin-mediated resistance to apoptosis.2015
- Author(s)
  Shinohara T, Sawada H, Otsuki S, Yodoya N, Kato T, Ohashi H, Zhang E, Saitoh S, Shimpo H, Maruyama K, Komada Y, Mitani Y.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol.
  
  Volume: 308(6) Issue: 6 Pages: L523-L538
- DOI
  10.1152/ajplung.00129.2014
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591574, KAKENHI-PROJECT-24592333, KAKENHI-PROJECT-24791057, KAKENHI-PROJECT-26461606, KAKENHI-PROJECT-15K09688
[Journal Article] Sarpogrelate hydrochloride, a serotonin 5HT2A receptor antagonist, ameliorates the development of chronic hypoxic pulmonary hypertension in rats2015
- Author(s)
  Zhang E, Maruyama J, et al.
- Journal Title
  
  J Anesth
  
  Volume: 29 Issue: 5 Pages: 715-723
- DOI
  10.1007/s00540-015-2015-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592333, KAKENHI-PROJECT-15K09199, KAKENHI-PROJECT-15K09688, KAKENHI-PROJECT-26461606
[Journal Article] Effect of thrombomodulin on the development of monocrotaline-induced pulmonary hypertension2014
- Author(s)
  Yamada Y, Maruyama J, Zhang E, Okada A, Yokochi A, Sawada H, Mitani Y, Hayashi T, Suzuki K, Maruyama K
- Journal Title
  
  J Anesth
  
  Volume: 28 Pages: 26-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592283
[Journal Article] Thrombomodulin protects against lung damage created by high level of oxygen with large tidal volume mechanical ventilation in rats.2014
- Author(s)
  Iwashita Y, Zhang E, Maruyama J, Yokochi A, Yamada Y, Sawada H, Mitani Y, Imai H, Suzuki K, Maruyama K.
- Journal Title
  
  J Intensice Care
  
  Volume: 2 Issue: 1 Pages: 57-57
- DOI
  10.1186/s40560-014-0057-0
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24592333
[Journal Article] 周術期の輸液管理2014
- Author(s)
  丸山一男、横地　歩、張　尓泉、岩下義明、藤岡正紀、今井　寛
- Journal Title
  
  救急医学
  
  Volume: ３７ Pages: 1895-1907
- Data Source
  KAKENHI-PROJECT-24592333
[Journal Article] Effect of thrombomodulin on the development of monocrotaline-induced pulmonary hypertension.2014
- Author(s)
  Yamada Y, Maruyama J, Zhang E, Maruyama K. et al
- Journal Title
  
  J Anesth
  
  Volume: 28(1) Issue: 1 Pages: 26-33
- DOI
  10.1007/s00540-013-1663-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591166, KAKENHI-PROJECT-24591574, KAKENHI-PROJECT-24592333, KAKENHI-PROJECT-24791056
[Journal Article] Age and sex dependency of monocrotaline-induced pulmonary hypertension2014
- Author(s)
  Maruyama J, Zhang E, Yokochi A, Okada A, Maruyama K.
- Journal Title
  
  Experimental & Clinical Cardiology
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592333
[Journal Article] Nitric oxide in the pathophysiology and treatment of pulmonary hypertension2013
- Author(s)
  Maruyama J, Yokochi A, Zhang E, Sawada H, Maruyama K.
- Journal Title
  
  Pulmonary Hypertension
  
  Volume: (ISBN 980-953-307-704-3)(InTech)
- DOI
  10.5772/55680
- ISBN
  9789535111658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591166, KAKENHI-PROJECT-23592283
[Journal Article] 周術期輸液とは2012
- Author(s)
  丸山一男、張尓泉、横地歩
- Journal Title
  
  内科
  
  Volume: 109 Pages: 240-244
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] 水・電解質と肺2012
- Author(s)
  張　尓泉
- Journal Title
  
  呼吸器ケア
  
  Volume: 11 Pages: 12-19
- Data Source
  KAKENHI-PROJECT-24592333
[Journal Article] 分離肺換気時の先読ポイント2011
- Author(s)
  張尓泉、横地歩、丸山一男
- Journal Title
  
  Ope nursing
  
  Volume: 26 Pages: 857-862
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] 筋弛緩薬と呼吸管理2011
- Author(s)
  丸山一男、張尓泉、山田康晴、横地歩、今井寛
- Journal Title
  
  人工呼吸
  
  Volume: 28 Pages: 161-167
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] 人工呼吸器関連の先読みポイント2011
- Author(s)
  山田康晴、張尓泉、横地歩、丸山一男
- Journal Title
  
  Ope nursing
  
  Volume: 26 Pages: 850-856
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] NO吸入療法2010
- Author(s)
  丸山一男、張尓泉、山田康晴、丸山淳子
- Journal Title
  
  救急医学
  
  Volume: 34 Pages: 1328-1333
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] Colforsin-induced vasodilation in chronic hypoxic pulmonary hypertension in rats2010
- Author(s)
  Yokochi A, Maruyama J, Zhang E, Mitani Y, Maruyama K
- Journal Title
  
  J Anesth
  
  Volume: 24(3) Pages: 432-440
- NAID
  10026545645
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] ALI/ARDSに対する一酸化窒素(NO)吸入療法とは?2010
- Author(s)
  丸山一男、張尓泉
- Journal Title
  
  救急・集中治療
  
  Volume: 22 Pages: 1259-1265
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] Effect of all-trans-retinoic acid on the development of chronic hypoxia -induced pulmonary hypertension2010
- Author(s)
  Zhang E, Maruyama J, Mitani Y, Yokochi A, Maruyama K
- Journal Title
  
  Circ J
  
  Volume: 74(8) Pages: 1696-1703
- NAID
  10026566030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] 一酸化窒素(NO)の臨床応用・治療効果2009
- Author(s)
  丸山一男、張尓泉、山田康晴、丸山淳子
- Journal Title
  
  ICUとCCU
  
  Volume: 33 Pages: 969-979
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] 成人でのNO吸入2009
- Author(s)
  丸山一男、張尓泉、山田康晴、丸山淳子
- Journal Title
  
  臨床麻酔
  
  Volume: 33 Pages: 984-994
- Data Source
  KAKENHI-PROJECT-21592003
[Journal Article] Ventilator-induced Lung Injury(VILI)に関する基礎研究2009
- Author(s)
  張尓泉、横地歩、岡田アムポン、他
- Journal Title
  
  臨床麻酔
  
  Volume: 33 Pages: 863-868
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] Role of BMPR2 Mutation in Monocrotaline-induced Pulmonary Hypertension: Analysis Using Rats with a Crispr/Cas9-induced Truncating BMPR2 mutation.2019
- Author(s)
  Kabwe JC, Sawada H, Mitani Y, Oshita H, Zhang E, Maruyama J, Hirayama M, Maruyama K
- Organizer
  Japanese Circulation Society. 2019. 3. 31. Yokohama Japan
- Data Source
  KAKENHI-PROJECT-17K11075
[Presentation] モノクロタリン（MCT)誘発性肺高血圧症に対するトロンボモジュリン（TM)の抑制効果の検討2014
- Author(s)
  張　尓泉、山田康晴、丸山淳子、大元文香、横地　歩、丸山一男
- Organizer
  第６１回日本麻酔科学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24592333
[Presentation] 従圧式人工呼吸におけるVILIラットモデルの作成.抄録集(2013) P.1812014
- Author(s)
  山田康晴、丸山淳子、張尓泉、上野浩明、小林睦、岩下義明、横地歩、澤田博文、大元文香、原田慎一、陳通、南波里奈、今井寛、丸山一男
- Organizer
  第35回日本呼吸療法医学会学術総会
- Place of Presentation
  東京
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] モノクロタリン（MCT)誘起性肺高血圧発症に対するトロンボモジュリン（TM）の抑制効果の検討2014
- Author(s)
  張尓泉、山田康晴、丸山淳子、横地歩、大元文香、丸山一男
- Organizer
  麻酔学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] 慢性低酸素曝露肺高血圧に対するH2Sによる血管病変の抑制効果2013
- Author(s)
  張　尓泉、南波里奈、陳　通、横地　歩、丸山淳子、丸山一男
- Organizer
  第６０回日本麻酔科学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24592333
[Presentation] 従圧式人工呼吸におけるVILIラットモデルの作成2013
- Author(s)
  山田康晴、丸山淳子、張尓泉、横地歩、澤田博文、丸山一男
- Organizer
  日本呼吸療法医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] モノクロタリン(MCT)誘発性肺高血圧発症に対するトロンボモジュリン(TM)の抑制効果の検討.麻酔(2014)Vol.63 P.63.(抄録)2013
- Author(s)
  張尓泉、山田康晴、丸山淳子、横地歩、大元文香、丸山一男
- Organizer
  第61回日本麻酔科学会
- Place of Presentation
  横浜
- Year and Date
  2013-07-21
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] 従圧式人工呼吸におけるVILIラットモデルの作成2013
- Author(s)
  山田康晴、丸山淳子、張　尓泉、上野浩明、小林　睦、岩下義明、横地　歩、澤田博文、大元文香、原田慎一、陳　通、南波里奈、今井　寛、丸山一男
- Organizer
  第35回日本呼吸療法医学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24592333
[Presentation] 慢性低酸素暴露肺高血圧に対するH2Sによる血管病変の抑制効果.麻酔(2013)Vol.62 P.75.(抄録)2013
- Author(s)
  張尓泉、南波里奈、陳通、横地歩、丸山淳子丸山一男
- Organizer
  第60回日本麻酔科学会
- Place of Presentation
  札幌
- Year and Date
  2013-05-23
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] 慢性低酸素暴露肺高血圧に対するH2Sによる血管病変の抑制効果2013
- Author(s)
  張尓泉,南波里奈、陳通、横地歩、丸山淳子、丸山一男
- Organizer
  麻酔学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] ラットにおけるVentilator-induced Lung Injury (VILI)の発生条件2011
- Author(s)
  張尓泉
- Organizer
  第３３回　日本呼吸療法学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23592283
[Presentation] 低酸素性肺高血圧発症におけるInterleukin-17(IL-17)の関与2011
- Author(s)
  中西雄紀、丸山淳子、張尓泉、横地歩、丸山一男
- Organizer
  日本麻酔科学会第58回学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] ラットにおけるVILI(Ventilator induced lung Injury)の発生条件2011
- Author(s)
  橋本祐樹、張尓泉、井波亜紗、大橋ひとみ、丸山淳子、山田康晴、大森彩加、丸山一男
- Organizer
  第33回日本呼吸療法医学会総会ポスター発表
- Place of Presentation
  横浜
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] シロスタゾールによるモノクロタリン誘起肺高血圧発症抑制効果2010
- Author(s)
  張尓泉, 他
- Organizer
  日本麻酔科学会
- Place of Presentation
  博多
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] 塩酸サルボグレラートによる低酸素性肺高血圧血管病変抑制作用2010
- Author(s)
  張尓泉, 丸山淳子, 横地歩, 他
- Organizer
  日本心血管作動物質学会
- Place of Presentation
  名古屋
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] シロスタゾールによるモノクロタリン誘起肺高血圧発症抑制作用2010
- Author(s)
  張尓泉、丸山淳子、横地歩、丸山一男
- Organizer
  第57回日本麻酔科学会ポスター発表
- Place of Presentation
  福岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-21592003
[Presentation] 肺高血圧血管病変に対するトロンボモジュリンによる抑制効果
- Author(s)
  張　尓泉、山田　康晴、丸山淳子、横地　歩、丸山一男
- Organizer
  日本麻酔科学会
- Place of Presentation
  横浜
- Year and Date
  2014-05-15 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-24592333
[Presentation] モノクロタリン誘起肺高血圧におけるeNOS発現とシロスタゾールによる発現抑制作用
- Author(s)
  張　尓泉
- Organizer
  日本麻酔科学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24592333

1. MARUYAMA Kazuo (20181828)

# of Collaborated Projects: 6 results

# of Collaborated Products: 39 results
2. MARUYAMA Junko (50263017)

# of Collaborated Projects: 6 results

# of Collaborated Products: 38 results
3. SAWADA Hirofumi (30362354)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. YOKICHI Ayumu (60359768)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
5. MITANI Yoshihide (60273380)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. KATO Taichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ZHANG Erquan 張 尓泉

Research Projects

Research Products

Co-Researchers

Analysis of TRPV channel in experimantal pulmonary hypertension and treatment

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Treatment with NO-dependent activated nitrite in experimental pulmonary hypertensionPrincipal Investigator

Principal Investigator

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Role of superoxide in pulmonary hypertension and treatment with xanthine oxidase inhibition

Principal Investigator

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Research Institution

pulmonary hypertension and hydrogen sulfate

Principal Investigator

Project Period (FY)

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Effects of hydrogen sulfide on ventilator induced lung injuryPrincipal Investigator

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Therapeutic target for pulmonary hypertension based on coagulative and inflammatory cascade analysis

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 呼吸管理 Q & A ２７章 NO吸入療法とは2013

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[Book] クリティカルケアにおける呼吸管理 １．呼吸生理2013

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[Book] 呼吸の生理.クリテイカルケアにおける呼吸管理.編集:氏家良人2013

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[Book] PULMONARY HYPERTENSION 4. Nitric oxide in pathophysiology and treatment of pulmonary hypertension2013

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[Book] Gas Biology Research in Clinical Practice2011

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[Book] Gas Biology Research in Clinical Practice2011

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[Journal Article] Potential Contribution of Phenotypically Modulated Smooth Muscle Cells and Related Inflammation in the Development of Experimental Obstructive Pulmonary Vasculopathy in Rats.2015

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[Journal Article] Macitentan reverses early obstructive pulmonary vasculopathy in rats: early intervention in overcoming the survivin-mediated resistance to apoptosis.2015

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[Journal Article] Sarpogrelate hydrochloride, a serotonin 5HT2A receptor antagonist, ameliorates the development of chronic hypoxic pulmonary hypertension in rats2015

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ZHANG Erquan 張尓泉

[Book] 呼吸管理　Q &　A　　　２７章　　NO吸入療法とは2013

[Book] クリティカルケアにおける呼吸管理　　１．呼吸生理2013

[Book] PULMONARY　HYPERTENSION　　4. Nitric oxide in pathophysiology and treatment of pulmonary hypertension2013