MASAKI Tomoyuki 正木智之

Researcher Number	30457717
Affiliation (based on the past Project Information) *help	2008 – 2010: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Except Principal Investigator Human pathology
Keywords	Except Principal Investigator 免疫学 / 病理学 / 細胞・組織 / アレルギー・ぜんそく / RSウイルス / シグナル伝達 / ヒト鼻粘膜 / RSウィルス / TLR / タイト結合 / 自然免疫

Regulation of human nasal mucosal barrier by tight junctions via innate immunity
- Principal Investigator
  
  KOJIMA Takashi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Sapporo Medical University

All 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.2011
- Author(s)
  Ohkuni T, Kojima T, Ogasawara N, Masaki T, Fuchimoto J, Kamekura R, Koizumi JI, Ichimiya S, Murata M, Tanaka S, Himi T, Sawada N
- Journal Title
  
  Toxicol Appl Pharmacol. 250
  
  Pages: 29-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids.2011
- Author(s)
  Masaki T, Fuchimoto J, Obata K, Kurose M, Shintani T, Sawada N, Himi T
- Journal Title
  
  Acta Otolaryngol 131
  
  Pages: 116-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells.2010
- Author(s)
  Kojima T, Fuchimoto J, Yamaguchi H, Ito T, Takasawa A, Ninomiya T, Kikuchi S, Ogasawara N, Ohkuni T, Masaki T, Hirata K, Himi T, Sawada N
- Journal Title
  
  J Cell Physiol 225
  
  Pages: 720-733
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] PPARγ agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells.2010
- Author(s)
  Ogasawara N, Kojima T, Go M, Ohkuni T, Koizumi J, Kamekura R, Masaki T, Murata M, Tanaka S, Fuchimoto J, Himi T, Sawada N
- Journal Title
  
  Pharmacol Res 61
  
  Pages: 489-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] RSウィルス感染症と喘鳴・喘息2010
- Author(s)
  堤裕幸, 平川賢史, 正木智之, 氷見徹夫, 岡林環樹, 横田伸一, 藤井暢弘, 小島隆, 澤田典均
- Journal Title
  
  小児耳鼻咽喉科 31(3)
  
  Pages: 248-252
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro.2009
- Author(s)
  Ohkuni T, Kojima T, Ogasawara N, Masaki T, Ninomiya T, Kikuchi S, Go M, Takano K, Himi T, Sawada N
- Journal Title
  
  Med Mol Morphol 42
  
  Pages: 204-211
- NAID
  10027269508
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] ヒト鼻粘膜の機能解析から見えてくること2009
- Author(s)
  氷見徹夫, 郷充, 近藤敦, 高野賢一, 正木智之, 小泉純一, 亀倉隆太, 大國毅, 小笠原徳子, 小島隆, 澤田典均
- Journal Title
  
  耳鼻咽喉科展望 52
  
  Pages: 9-18
- NAID
  130004911712
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] Induction of JAM-A during differentiation of human THP-1 dendritic cells.2009
- Author(s)
  Ogasawara N, Kojima T, Go M, Fuchimoto J, Kamekura R, Koizumi J, Ohkuni T, Masaki T, Murata M, Tanaka S, Ichimiya S, Himi T, Sawada N
- Journal Title
  
  Biochem Biophys Res Commun 389
  
  Pages: 543-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Journal Article] An NF-κB signaling pathway via PKCδ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells.
- Author(s)
  Masaki T, Kojima T, Okabayashi T, Ogasawara N, Ohkuni T, Obata K, Takasawa A, Murata M, Tanaka S, Hirakawa S, Fuchimoto J, Ninomiya T, Fujii N, Tsutsumi H, Himi T, Sawada N
- Journal Title
  
  Mol Biol Cell in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] RSV感染鼻粘膜上皮細胞におけるIII型インターフェロンの重要性2010
- Author(s)
  岡林環樹, 小島隆, 正木智之, 横田伸一, 堤裕幸, 氷見徹夫, 澤田典均, 藤井暢弘
- Organizer
  2010日本インターフェロンサイトカイン学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] RSウイルス感染ヒト鼻粘膜上皮細胞におけるタイト結合の誘導2010
- Author(s)
  正木智之, 小島隆, 大國毅, 小笠原徳子, 氷見徹夫, 村田雅樹, 田中敏, 澤田典均
- Organizer
  第99回日本病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] RSウイルス感染ヒト鼻粘膜上皮細胞におけるタイト結合の誘導2010
- Author(s)
  正木智之, 小島隆, 大國毅, 小笠原徳子, 岡林環樹, 藤井暢弘, 堤裕幸, 澤田典均, 氷見徹夫
- Organizer
  第28回日本耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] ヒト鼻粘膜上皮細胞を用いたホップ水抽出物のTSLP産生抑制効果2010
- Author(s)
  渕本潤, 小島隆, 小林直之, 亀倉隆太, 郷充, 大國毅, 小笠原徳子, 正木智之, 伊藤一敏, 氷見徹夫, 澤田典均
- Organizer
  第49回日本鼻科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] RSウイルス感染によるヒト鼻粘膜上皮細胞のシグナル応答2010
- Author(s)
  正木智之, 小島隆, 大國毅, 小笠原徳子, 岡林環樹, 藤井暢弘, 堤裕幸, 澤田典均, 氷見徹夫
- Organizer
  第49回日本鼻科学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] 核内受容体PPAR-γを介したヒト鼻粘膜におけるタイト結合の発現調節機構2009
- Author(s)
  小笠原徳子, 小島隆, 郷充, 亀倉隆太, 大國毅, 正木智之, 村田雅樹, 田中敏, 千葉英樹, 氷見徹夫, 澤田典均
- Organizer
  第98回日本病理学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] 正常ヒト鼻粘膜上皮バリア調節機構へのTLRの関与2009
- Author(s)
  大國毅, 小島隆, 小笠原徳子, 正木智之, 氷見徹夫, 澤田典均
- Organizer
  第8回コネキシン研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590346
[Presentation] ウイルス感染とヒト鼻粘膜バリア2009
- Author(s)
  正木智之, 小島隆, 大國毅, 小笠原徳子, 澤田典均, 氷見徹夫
- Organizer
  第48回日本鼻科学会
- Place of Presentation
  島根
- Data Source
  KAKENHI-PROJECT-20590346

1. KOJIMA Takashi (30260764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
2. TANAKA Satoshi (30374250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. MURATA Masaki (10404592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 小笠原徳子 (00438061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. 山口洋志 (80457704)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

MASAKI Tomoyuki 正木 智之

Research Projects

Research Products

Co-Researchers

Regulation of human nasal mucosal barrier by tight junctions via innate immunity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids.2011

Author(s)

Journal Title

Data Source

[Journal Article] c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] PPARγ agonists upregulate the barrier function of tight junctions via a PKC pathway in human nasal epithelial cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] RSウィルス感染症と喘鳴・喘息2010

Author(s)

Journal Title

Data Source

[Journal Article] Expression and localization of tricellulin in human nasal epithelial cells in vivo and in vitro.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] ヒト鼻粘膜の機能解析から見えてくること2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Induction of JAM-A during differentiation of human THP-1 dendritic cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] An NF-κB signaling pathway via PKCδ regulates replication of respiratory syncytial virus in polarized normal human nasal epithelial cells.

Author(s)

Journal Title

Data Source

[Presentation] RSV感染鼻粘膜上皮細胞におけるIII型インターフェロンの重要性2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] RSウイルス感染ヒト鼻粘膜上皮細胞におけるタイト結合の誘導2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] RSウイルス感染ヒト鼻粘膜上皮細胞におけるタイト結合の誘導2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] ヒト鼻粘膜上皮細胞を用いたホップ水抽出物のTSLP産生抑制効果2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] RSウイルス感染によるヒト鼻粘膜上皮細胞のシグナル応答2010

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 核内受容体PPAR-γを介したヒト鼻粘膜におけるタイト結合の発現調節機構2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 正常ヒト鼻粘膜上皮バリア調節機構へのTLRの関与2009

Author(s)

MASAKI Tomoyuki 正木智之