Nasu Ryo 那須亮

… Alternative Names

NASU Ryo 那須亮

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Researcher Number	30466859
Other IDs	https://orcid.org/0000-0002-4108-7021
Affiliation (Current)	2024: 千葉大学, 大学院医学研究院, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 千葉大学, 大学院医学研究院, 講師 2016 – 2020: 千葉大学, 大学院医学研究院, 特任助教 2015: 東海大学, 医学部, 助教 2013 – 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2012: 東京大学, 分子細胞生物学研究所, 研究員 2008 – 2011: The University of Tokyo, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor biology / Tumor biology / Cell biology Except Principal Investigator Transformative Research Areas, Section (III) / Biological Sciences
Keywords	Principal Investigator がん免疫 / がん免疫療法 / 所属リンパ節 / 腫瘍特異的CD8T細胞 / CD69 / LGR5 / Wntシグナル / 癌幹細胞 / 癌 / クロマチン … More / 分化運命決定 / 1細胞解析 / 腫瘍内T細胞分化 / 腫瘍内CD8T細胞分化 / 分化型CD8T細胞 / 幹細胞様CD8T細胞 / 免疫逃避機構 / 免疫チェックポイント阻害剤 / 細胞傷害性T細胞 / 腫瘍免疫 / Axin1 / APC / 膠芽腫 / がん幹細胞 / がん / デスモソーム / CD133 / 卵巣明細胞癌 / MDM2 / p53 / 細胞死 / 癌抑制遺伝子 / C-Jun / JmiC / HP1 / JmjC / c-Jun / 細胞周期 … More Except Principal Investigator 自然免疫型T細胞 / 抗腫瘍免疫 / 組織特異性 / 腫瘍免疫 / γδT細胞 / CD69 / T細胞 / β-catenin / B9L / Sam68 / 細胞運動 / Dlg / G蛋白質 / GEF / 血管新生 / 神経突起伸長 / 癌抑制遺伝子 / RICS / カドヘリン / beta-catenin / 細胞運動・浸潤 / 細胞がん化 / Wnt / がん幹細胞 / Asef / APC / p53 / 増殖 / アポトーシス / がん遺伝子 / がん抑制遺伝子 Less

Development of immunotherapy that controls the fate determination of tumor-specific CD8T cells in tumor-draining lymph nodesPrincipal Investigator
- Principal Investigator
  
  那須亮
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Mechanisms of immune homeostasis and responses based on T cell mediated self-recognition
- Principal Investigator
  
  木村元子
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Chiba University
Development of cancer immunotherapy based on understanding of intratumoral T-cell differentiation originating from stem-like CD8T cellsPrincipal Investigator
- Principal Investigator
  
  Nasu Ryo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Development of new cancer immunotherapy that targets the CD69-Myl9/12 systemPrincipal Investigator
- Principal Investigator
  
  Nasu Ryo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Chiba University
Development of novel treatment strategies targeting the R-spondin-LGR-APC axis in glioblastoma stem cellsPrincipal Investigator
- Principal Investigator
  
  NASU Ryo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Chiba University
  Tokai University
Development of therapy that targets ovarian clear cell carcinoma stem cellsPrincipal Investigator
- Principal Investigator
  
  NASU Ryo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto Prefectural University of Medicine
  The University of Tokyo
Study of the function of the nuclear protein LDOC1 in the regulation of MDM2-mediated p53 ubiquitinationPrincipal Investigator
- Principal Investigator
  
  NASU Ryo
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo
Study on the function of the transcriptional repressor Fbl10 in the regulation of c-JunPrincipal Investigator
- Principal Investigator
  
  NASU Ryo
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Molecular mechanism of tumor cell growth
- Principal Investigator
  
  AKIYAMA Tetsu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、 Kiuchi Masahiro、 Aoki Ami、Wang Yangsong, Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、 Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22H05189
[Journal Article] CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、Kiuchi Masahiro、Aoki Ami、Wang Yangsong、Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 11 Issue: 8 Pages: 1085-1099
- DOI
  10.1158/2326-6066.cir-22-0406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15485, KAKENHI-PROJECT-23K19462, KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-23K24147, KAKENHI-PROJECT-23K24441, KAKENHI-PROJECT-19H05650
[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023
- Author(s)
  Koyama-Nasu Ryo、Kimura Motoko Y.、 Kiuchi Masahiro、 Aoki Ami、Wang Yangsong, Mita Yukiyoshi、Hasegawa Ichita、Endo Yukihiro、Onodera Atsushi、Hirahara Kiyoshi、 Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Cancer Immunology Research
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07234
[Journal Article] The cellular and molecular basis of CD69 function in anti-tumor immunity2022
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Hasegawa Ichita、Endo Yukihiro、Nakayama Toshinori、Kimura Motoko Y
- Journal Title
  
  International Immunology
  
  Volume: 34 Issue: 11 Pages: 555-561
- DOI
  10.1093/intimm/dxac024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07234, KAKENHI-PLANNED-22H05189, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03464
[Journal Article] IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation2021
- Author(s)
  Sarkar Murshed H.、Yagi Ryoji、Endo Yukihiro、Koyama-Nasu Ryo、Wang Yangsong、Hasegawa Ichita、Ito Toshihiro、Junttila Ilkka S.、Zhu Jinfang、Kimura Motoko Y.、Nakayama Toshinori
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: e0260204-e0260204
- DOI
  10.1371/journal.pone.0260204
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21537, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-21K07234, KAKENHI-PROJECT-19H05650
[Journal Article] Essential Role for CD30-Transglutaminase 2 Axis in Memory Th1 and Th17 Cell Generation2020
- Author(s)
  Suzuki Akane S.、Yagi Ryoji、Kimura Motoko Y.、Iwamura Chiaki、Shinoda Kenta、Onodera Atsushi、Hirahara Kiyoshi、Tumes Damon J.、Koyama-Nasu Ryo、Iismaa Siiri E.、Graham Robert M.、Motohashi Shinichiro、Nakayama Toshinori
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 11 Pages: 1536-1536
- DOI
  10.3389/fimmu.2020.01536
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08769, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K23838
[Journal Article] CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy2020
- Author(s)
  Hara Ayaka、Koyama-Nasu Ryo、Takami Mariko、Toyoda Takahide、Aoki Takahiro、Ihara Fumie、Kobayashi Masayoshi、Hirono Seiichiro、Matsutani Tomoo、Nakayama Toshinori、Iwadate Yasuo、Motohashi Shinichiro
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 5 Pages: 1239-1254
- DOI
  10.1007/s00262-020-02742-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07652, KAKENHI-PROJECT-20K17952, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K18379, KAKENHI-PROJECT-19K09451, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19H05650
[Journal Article] Activated invariant natural killer T cells directly recognize leukemia cells in a CD1d‐independent manner2020
- Author(s)
  Aoki Takahiro、Takami Mariko、Takatani Tomozumi、Motoyoshi Kiwamu、Ishii Ayana、Hara Ayaka、Toyoda Takahide、Okada Reona、Hino Moeko、Koyama‐Nasu Ryo、Kiuchi Masahiro、Hirahara Kiyoshi、Kimura Motoko Y.、Nakayama Toshinori、Shimojo Naoki、Motohashi Shinichiro
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 7 Pages: 2223-2233
- DOI
  10.1111/cas.14428
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07652, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21537, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-18H02892, KAKENHI-PROJECT-20H03464, KAKENHI-PROJECT-20H03685, KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-19K18379
[Journal Article] A new therapeutic target: the CD69-Myl9 system in immune responses2019
- Author(s)
  Kimura Motoko Y.、Koyama-Nasu Ryo、Yagi Ryoji、Nakayama Toshinori
- Journal Title
  
  Seminars in Immunopathology
  
  Volume: - Issue: 3 Pages: 349-358
- DOI
  10.1007/s00281-019-00734-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07165, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-18K07257, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18K19466
[Journal Article] ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis2019
- Author(s)
  Yusuke Endo, Atsushi Onodera, Kazushige Obata-Ninomiya, Ryo Koyama-Nasu, Hikari K. Asou, Toshihiro Ito, Takeshi Yamamoto, Toshio Kanno, Takahiro Nakajima, Kenji Ishiwata, Hirotaka Kanuka, Damon J. Tumes, Toshinori Nakayama
- Journal Title
  
  Nature Metabolism
  
  Volume: 1(2) Issue: 2 Pages: 261-275
- DOI
  10.1038/s42255-018-0025-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18K07257
[Journal Article] SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity2018
- Author(s)
  Funato K, Hayashi T, Echizen K, Negishi L, Shimizu N, Koyama-Nasu R, Nasu-Nishimura Y, Morishita Y, Tabar V, Todo T, Ino Y, Mukasa A, Saito N & Akiyama T.
- Journal Title
  
  EMBO Reports
  
  Volume: 19 Issue: 11 Pages: 45587-45587
- DOI
  10.15252/embr.201745587
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07257, KAKENHI-ORGANIZER-17H06324, KAKENHI-PLANNED-17H06325, KAKENHI-PROJECT-17H01537, KAKENHI-PROJECT-16K15641, KAKENHI-PROJECT-17H04300
[Journal Article] Crucial role of CD69 in anti-tumor immunity through regulating the exhaustion of tumor-infiltrating T cells2018
- Author(s)
  Mita Y, Kimura MY, Hayashizaki K, Koyama-Nasu R, Ito T, Motohashi S, Okamoto Y & Nakayama T
- Journal Title
  
  International Immunology
  
  Volume: 30 Issue: 12 Pages: 559-567
- DOI
  10.1093/intimm/dxy050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07257, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18H02892
[Journal Article] Anti-tumor immunity via the superoxide-eosinophil axis induced by a lipophilic component of Mycobacterium lipomannan2017
- Author(s)
  Ito Toshihiro、Hirahara Kiyoshi、Onodera Atsushi、Koyama-Nasu Ryo、Yano Ikuya、Nakayama Toshinori
- Journal Title
  
  Int. Immunol
  
  Volume: 29 Issue: 9 Pages: 411-421
- DOI
  10.1093/intimm/dxx051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-15K08522
[Journal Article] Imbalanced expression of polycistronic miRNA in acute myeloid leukemia.2017
- Author(s)
  Kotaki R, Higuchi H, Ogiya D, Katahira Y, Kurosaki N, Yukihira N, Ogata J, Yamamoto H, Mohamad Alba S, Azhim A, Kitajima T, Inoue S, Morishita K, Ono K, Koyama-Nasu R, Kotani A.
- Journal Title
  
  Int J Hematol.
  
  Volume: 106 Issue: 6 Pages: 811-819
- DOI
  10.1007/s12185-017-2314-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17H04212, KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-17K19590, KAKENHI-PUBLICLY-17H05599
[Journal Article] miRNAs in Normal and Malignant Hematopoiesis2017
- Author(s)
  Ryutaro Kotaki, Ryo Koyama-Nasu, Natsuko Yamakawa, Ai Kotani
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18(7) Issue: 7 Pages: 1495-1495
- DOI
  10.3390/ijms18071495
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04212, KAKENHI-PROJECT-15K06838
[Journal Article] Integrative Network Analysis Combined with Quantitative Phosphoproteomics Reveals TGFBR2 as a Novel Regulator of Glioblastoma Stem Cell Properties2016
- Author(s)
  Narushima Y, Kozuka-Hata H, Koyama-Nasu R, Tsumoto K, Inoue J, Akiyama T & Oyama M.
- Journal Title
  
  Molecular and Cellular Proteomics
  
  Volume: 15 Issue: 3 Pages: 1017-1031
- DOI
  10.1074/mcp.m115.049999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06838, KAKENHI-PROJECT-26505001, KAKENHI-PLANNED-22117002, KAKENHI-PUBLICLY-15H01176, KAKENHI-ORGANIZER-22117001, KAKENHI-PROJECT-25249115, KAKENHI-PROJECT-26290036
[Journal Article] SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity.2015
- Author(s)
  Hiraoka K, Hayashi T, Kaneko R, Nasu-Nishimura Y, Koyama-Nasu R, Kawasaki Y, Akiyama T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 460 Issue: 2 Pages: 4097-4109
- DOI
  10.1016/j.bbrc.2015.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24501313, KAKENHI-PROJECT-25290043
[Journal Article] Thr160 of Axin1 is critical for the formation and function of the β-catenin destruction complex.2015
- Author(s)
  Koyama-Nasu R, Hayashi T, Nasu-Nishimura Y, Akiyama T, Yamanaka R
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 459 Issue: 3 Pages: 411-415
- DOI
  10.1016/j.bbrc.2015.02.118
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24501313, KAKENHI-PROJECT-24390347, KAKENHI-PROJECT-26670646
[Journal Article] 5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex2014
- Author(s)
  Hiroki Takai, Tetsu Akiyama et al.
- Journal Title
  
  Cell Reports
  
  Volume: 9 Issue: 1 Pages: 48-60
- DOI
  10.1016/j.celrep.2014.08.071
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J10908, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24390340, KAKENHI-PROJECT-24501313, KAKENHI-PUBLICLY-25134702, KAKENHI-PROJECT-25620125, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26253073, KAKENHI-PROJECT-26293321, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26702035, KAKENHI-PLANNED-23114003, KAKENHI-PLANNED-26113003
[Journal Article] PCDH10 is required for the tumorigenicity of glioblastoma cells2014
- Author(s)
  Kanae Echizen, Mitsutoshi Nakada , Tomoatsu Hayashi, Hemragul Sabit, Takuya Furuta, Miyuki Nakai, Ryo Koyama-Nasu, Yukiko Nishimura, Kenzui Taniue, Yasuyuki Morishita, Shinji Hirano, Kenta Terai, Tomoki Todo, Yasushi Ino, Akitake Mukasa, Shunsaku Takayanagi, Ryohei Ohtani, Nobuhito Saito, Tetsu Akiyama
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 444 Issue: 1 Pages: 13-18
- DOI
  10.1016/j.bbrc.2013.12.138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-23390343, KAKENHI-PROJECT-23592117, KAKENHI-PROJECT-24501313, KAKENHI-PUBLICLY-25134702, KAKENHI-PROJECT-25430037, KAKENHI-PROJECT-25670138, KAKENHI-PROJECT-25830073, KAKENHI-PROJECT-26253073
[Journal Article] The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells2013
- Author(s)
  R Koyama-Nasu, R Haruta, Y Nasu-Nishimura, K Taniue, Y Katou, K Shirahige, T Todo, Y Ino, A Mukasa, N Saito, M Matsui, R Takahashi, A Hoshino-Okubo, H Sugano, E Manabe, K Funato and T Akiyam
- Journal Title
  
  Oncogene
  
  Volume: 33 Issue: 17 Pages: 2236-2244
- DOI
  10.1038/onc.2013.168
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24501313, KAKENHI-PROJECT-25670138, KAKENHI-PROJECT-25830073, KAKENHI-PROJECT-26253073
[Journal Article] The cancer stem cell marker CD133 interacts with plakoglobin and controls desmoglein-2 protein levels.2013
- Author(s)
  Koyama-Nasu R, Takahashi R, Yanagida S, Nasu-Nishimura Y, Oyama M, Kozuka-Hata H, Haruta R, Manabe E, Hoshino-Okubo A, Omi H, Yanaihara N, Okamoto A, Tanaka T, and Akiyama T.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 1 Pages: e53710-e53710
- DOI
  10.1371/journal.pone.0053710
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24501313
[Journal Article] The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells2013
- Author(s)
  R Koyama-Nasu, Y Nasu-Nishimura, T Todo, Y Ino, N Saito, H Aburatani, K Funato, K Echizen, H Sugano, R Haruta, M Matsui, R Takahashi, E Manabe, T Oda and T Akiyama
- Journal Title
  
  Oncogene
  
  Volume: 32 Issue: 33 Pages: 3840-3845
- DOI
  10.1038/onc.2012.399
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112004, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24501313, KAKENHI-PROJECT-25670138
[Journal Article] Global proteome analysis of glioblastoma stem cells by high-resolution mass spectrometry2012
- Author(s)
  Kozuka-Hata H, Nasu-Nishimura Y, Koyama-Nasu R, Ao-Kondo H, Tsumoto K, Akiyama T & Oyama M
- Journal Title
  
  Current Topics in Peptide & Protein Research
  
  Volume: 13 Pages: 1-47
- Data Source
  KAKENHI-PROJECT-24501313
[Journal Article] Phosphoproteome of human glioblastoma initiating cells reveals novel signaling regulators encoded by the transcriptome.2012
- Author(s)
  Kozuka-Hata H, Nasu-Nishimura Y, Koyama-Nasu R, Ao-Kondo H, Tsumoto K, Akiyama T, and Oyama M.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 8 Pages: e43398-e43398
- DOI
  10.1371/journal.pone.0043398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510254, KAKENHI-PROJECT-24501313
[Journal Article] PX-RICS mediates ER-to-Golgi transport of the N-cadherin/-catenin complex.2008
- Author(s)
  Nakamura T., Hayashi T., Nasu-Nishimura Y., Sakaue F., Okabe T., Ohwada S., Matsuura K., Akiyama T.
- Journal Title
  
  Genes Dev. 22
  
  Pages: 1244-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] Role of the Rho GTPase-activating protein RICS in neurite outgrowth.2006
- Author(s)
  Nasu-Nishimura Y.
- Journal Title
  
  Genes Cells 11
  
  Pages: 607-614
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] Role of the Rho GTPhase-activating protein RICS in neurite outgrowth.
- Author(s)
  Nasu-Nishimura, Y.
- Journal Title
  
  Genes Cells (in press.)
- Data Source
  KAKENHI-PROJECT-17014011
[Presentation] Role of CD69 on thymic regulatory T cell development2024
- Author(s)
  Endo, Y., Hasegawa, I., Ueno, T., Sasayama, T., Wang, Y., Kano, S., Nasu,R., Kimura, M.Y.
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] The role of central tolerance during tumor progression2024
- Author(s)
  Wang, Y., Nasu, R., Hasegawa, I., Endo, Y., Kano, S., Kimura, M.Y.
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 controls tumor-specific CD8T-cell fate in tumor-draining lymph nodes2024
- Author(s)
  Nasu, R., Wang, Y., Endo, Y., Hasegawa, I., Mita, Y., Motohashi, S., Nakayama, T., Kimura, M.Y.
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates tumor-specific CD8 T cell differentiation in tumor-draining lymph nodes2024
- Author(s)
  Ryo Nasu, Yangsong Wang, Yukihiro Endo, Ichita Hasegawa, Yukiyoshi Mita, Shinichiro Motohashi, Toshinori Nakayama, Motoko Y. Kimura
- Organizer
  第52回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] Role of CD69 in long-term maintenance of IL-17 producing gd T cells2024
- Author(s)
  Hasegawa, I., Endo, Y., Wang, Y., Kano S., Iijima Y., Nasu, R., Kimura, M.Y.
- Organizer
  Dr. Toshinori Nakayama Memorial cMAV-cSIMVa Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates tumor-specific CD8 T cell differentiation in tumor-draining lymph nodes2024
- Author(s)
  Nasu, R., Wang, Y., Endo, Y., Hasegawa, I., Mita, Y., Motohashi, S., Nakayama, T., Kimura, M.Y.
- Organizer
  The 52nd Annual Meeting of The Japanese Society for Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates anti-tumor CD8T cell responses2023
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] IL-17産生gd型T細胞の恒常性維持におけるCD69分子の機能について2023
- Author(s)
  Hasegawa, I., Endo, Y., Wang, Y., Kano S., Iijima Y., Nasu, R., Kimura, M.Y.
- Organizer
  学術変革領域研究(A) 令和5年度若手ワークショップ
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Role of CD69 on thymic regulatory T cell development2023
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Role of CD69 in long-term maintenance of IL-17 producing gd T cells2023
- Author(s)
  Hasegawa, I., Endo, Y., Wang, Y., Kano S., Iijima Y., Nasu, R., Kimura, M.Y.
- Organizer
  学術変革領域研究(A) R5年度学術会議
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Does tumor affect thymic T cell generation?2023
- Author(s)
  Wang, Y., Nasu, R., Hasegawa, I., Endo, Y., Kano S., Kimura, M.Y.
- Organizer
  第32回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] The essential role of central tolerance in tumor progression2023
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  International Symposium for Future Mucosal Vaccines
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 controls differentiation of tumor-specific CD8T cells in tumor-draining lymph nodes2023
- Author(s)
  Ryo Nasu, Yangsong Wang, Yukihiro Endo, Ichita Hasegawa, Yukiyoshi Mita, Shinichiro Motohashi, Toshinori Nakayama, Motoko Y. Kimura
- Organizer
  第82回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] CD69 controls differentiation of tumor-specific CD8T cells in tumor-draining lymph nodes2023
- Author(s)
  Nasu, R., Wang, Y., Endo, Y., Hasegawa, I., Mita, Y., Motohashi, S., Nakayama, T., Kimura, M.Y.
- Organizer
  The 82nd annual meeting of the japanese cancer association
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69による制御性T細胞分化制御2023
- Author(s)
  遠藤将大, 上野達矢, 長谷川一太, Wang Yangsong, 加納舜佳, 那須亮, 木村元子
- Organizer
  第32回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] 腫瘍特異的CD8T細胞の分化運命決定機構2022
- Author(s)
  那須亮, Wang Yangsong, 長谷川一太, 遠藤将大, 中山俊憲, 木村元子.
- Organizer
  KTCC第31回学術集会
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] 胸腺内制御性R細胞分化におけるCD69の役割2022
- Author(s)
  遠藤将大、上野達矢、長谷川一太、Wang Yangsong、那須亮、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] The essential role of central tolerance in tumor progression2022
- Author(s)
  Wang Yangsong、Koyama-Nasu Ryo、 Hasegawa Ichita、Endo Yukihiro、Kano Shunka, Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] Role of CD69 on thymic regulatory T cell development2022
- Author(s)
  Endo Yukihiro、Ueno Tatsuya、Hasegawa Ichita、Wang Yangsong、Koyama-Nasu Ryo、 Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates anti-tumor CD8T cell responses2022
- Author(s)
  Koyama-Nasu Ryo、Wang Yangsong、Endo Yukihiro、Hasegawa Ichita、Ueno Tatsuya、Mita Yukiyoshi、Motohashi Shinichiro、Nakayama Toshinori、Kimura Motoko Y.
- Organizer
  第51回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69 regulates anti-tumor CD8T cell responses2022
- Author(s)
  Ryo Nasu, Yangsong Wang, Yukihiro Endo, Ichita Hasegawa, Atsushi Onodera, Shinichiro Motohashi, Toshinori Nakayama, Motoko Y. Kimura
- Organizer
  第51回日本免疫学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] 腫瘍特異的CD8T細胞の分化運命決定機構2022
- Author(s)
  那須亮、Wang Yangsong、長谷川一太、遠藤将大、中山俊憲、木村元子
- Organizer
  第31回Kyoto T Cell Congerence学術集会
- Data Source
  KAKENHI-PLANNED-22H05189
[Presentation] CD69-Myl9システムと炎症制御2021
- Author(s)
  木村元子, 横山将也, 小林弘信, 林﨑浩史, 遠藤将大, Wang Yangsong, 長谷川一太, 那須亮, 中山俊憲
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] CD69 regulates anti-tumor immunity2021
- Author(s)
  Kimura M., Nasu R., Mita Y., Wang Y., Endo Y., Hasegawa I., Motohashi S., Nakayama T.
- Organizer
  The 50th Annual Meeting of the Japanese Society for Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07234
[Presentation] Inhibition of acetyl-CoA carboxylase enhances memory Th2 cell generation and Th2 mediated anti-tumor immunity2019
- Author(s)
  那須亮、遠藤祐介、伊藤俊広、木村元子、中山俊憲
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] がん免疫療法の新たなターゲットとしてのCD69の可能性2019
- Author(s)
  木村元子、那須亮、三田恭義、中山俊憲
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] 膠芽腫に発現するCD1d分子はNKT細胞を用いた免疫療法における有望な標的となる2019
- Author(s)
  原彩佳、那須亮、高見真理子、廣野誠一郎、松谷智郎,、中山俊憲,、岩立康男、本橋新一郎
- Organizer
  第23回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] CD1d expression in glioblastoma is a promising target for NKT cell- based cancer immunotherapy2019
- Author(s)
  Hara, A., Nasu, R., Takami, M., Hirono, S., Matsutani, T., Nakayama, T., Iwadate, Y., Motohashi, S.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] CD1d expression in glioblastoma is a promising target for NKT cell- based cancer immunotherapy2019
- Author(s)
  Hara, A., Nasu, R., Takami, M., Hirono, S., Matsutani, T., Nakayama, T., Iwadate, Y., Motohashi, S.
- Organizer
  EMBO workshop CD1-MR1
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] nti-tumor immunity via the superoxide-eosinophil axis induced by lipophilic component of Mycobacterium lipomannan2018
- Author(s)
  Ito T, Hirahara K, Nasu R, Yano I, Motohashi S & Nakayama T
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] Crucial role for CD69 in anti-tumor immunity2018
- Author(s)
  Mita Y, Kimura M, Nasu R, Motohashi S, Okamoto Y & Nakayama T
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] CD69による抗腫瘍免疫制御2018
- Author(s)
  三田恭義, 木村元子, 那須亮, 本橋新一郎, 岡本美孝, 中山俊憲
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] 好酸球およびエフェクター記憶 Th2 細胞の活性化によるMycobacterium lipomannanの抗腫瘍免疫2018
- Author(s)
  伊藤俊広, 平原潔, 那須亮, 小野寺淳, 矢野郁也, 本橋新一郎, 中山俊憲
- Organizer
  第22回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K07257
[Presentation] Functional and comprehensive investigation of microRNA targeting Notch receptors2016
- Author(s)
  那須亮, 奥山一生, 扇屋大輔, 穂積勝人, 村田暁彦, 安藤潔, 幸谷愛
- Organizer
  第14回幹細胞シンポジウム
- Place of Presentation
  兵庫県立淡路夢舞台国際会議場 (兵庫県淡路市))
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] Identification of Notch-targeting miRNA that regulates B cell development and has therapeutic potential in T-ALL.2016
- Author(s)
  那須亮, 奥山一生, 扇屋大輔, 穂積勝人, 村田暁彦, 安藤潔, 幸谷愛
- Organizer
  第20回造血器腫瘍研究会
- Place of Presentation
  かずさアーク (千葉)
- Year and Date
  2016-02-12
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] 高深度定量リン酸化プロテオミクスと大規模インタラクトーム情報を基盤とする膠芽腫幹細胞情報伝達系の統合ネットワーク解析2016
- Author(s)
  秦裕子, 成島悠太, 廣木朋子, 那須亮, 津本浩平, 井上純一郎, 秋山徹, 尾山大明
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市)
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] 高精度定量リン酸化プロテオミクスに基づく統合ネットワーク解析による膠芽腫幹細胞分化制御因子の同定2015
- Author(s)
  成島悠太, 秦裕子, 那須亮, 津本浩平, 井上純一郎, 秋山徹, 尾山大明
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (兵庫)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] Identification of Notch-targeting miRNA that regulates B cell development and has therapeutic potential in T-ALL.2015
- Author(s)
  那須亮, 奥山一生, 扇屋大輔, 穂積勝人, 村田暁彦, 安藤潔, 幸谷愛
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場 (愛知)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] mTOR阻害剤を用いた膠芽腫幹細胞プロテオーム及びリン酸化プロテオームに関する統合摂動実験2015
- Author(s)
  秦裕子, 廣木朋子, 那須亮, 津本浩平, 井上純一郎, 秋山徹, 尾山大明
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (兵庫)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06838
[Presentation] The SOX2-pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells2012
- Author(s)
  那須亮、春田諒、西村教子、谷上賢端、加藤由起、白髭克彦、藤堂具紀、稲生靖、武笠晃丈、齊藤延人、松井真弓、髙橋理那、大久保明美、菅野陽元、真鍋瑛美、船戸洸佑、秋山徹
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡(福岡)
- Data Source
  KAKENHI-PROJECT-24501313
[Presentation] The cancer stem cell marker CD133 is required for desmosome formation2012
- Author(s)
  那須亮、髙橋理那、柳田聡、西村教子、尾山大明、秦裕子、春田諒、眞鍋瑛美、大久保明美、尾見裕子、矢内原臨、岡本愛光、田中忠男、秋山徹
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌(北海道)
- Data Source
  KAKENHI-PROJECT-24501313
[Presentation] The molecular mechanisms of the regulation of Wnt signaling in glioblastoma stem cells2011
- Author(s)
  那須亮、西村教子、川崎善博、藤堂具紀、稲生靖、武笠晃丈、高柳俊作、斉藤延人、新井健明、眞鍋瑛美、秋山徹
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22700871
[Presentation] The critical role of cyclin D2 in glioblastoma stem cells2010
- Author(s)
  那須亮、西村教子、藤堂具紀、稲生靖、齊藤延人、油谷浩幸、船戸洸佑、越前佳奈恵、春田諒、松井真弓、高橋理那、小田健昭、秋山徹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場、リーガロイヤルホテル大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22700871
[Presentation] The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun2008
- Author(s)
  那須亮
- Organizer
  第21回内藤コンファレンス「細胞核ダイナミクスとRNA[1]」
- Place of Presentation
  八ヶ岳ロイヤルホテル
- Year and Date
  2008-06-25
- Data Source
  KAKENHI-PROJECT-20770154
[Presentation] The F-box protein Fbl10 is a novel transcriptional repressor of c-Jun
- Author(s)
  Ryo Koyama-Nasu, Gregory David, Michele Pagano, Naoko Tanese
- Organizer
  第21回内藤コンファレンス「細胞核ダイナミクスとrna[I]」
- Data Source
  KAKENHI-PROJECT-20770154

1. 岩立康男 (70272309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. 本橋新一郎 (60345022)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. AKIYAMA Tetsu (70150745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. KAWASAKI Yoshihiro (10376642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAMURA Tsutomu (30302798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 木村元子 (00345018)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
7. OYAMA Masaaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. IWAMURA Chiaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 平原潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 尾野亘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 秦裕子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 高見真理子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 幸谷愛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 木内政宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 八木良二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小野寺淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nasu Ryo 那須 亮

NASU Ryo 那須 亮

Research Projects

Research Products

Co-Researchers

Development of immunotherapy that controls the fate determination of tumor-specific CD8T cells in tumor-draining lymph nodesPrincipal Investigator

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Mechanisms of immune homeostasis and responses based on T cell mediated self-recognition

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Development of cancer immunotherapy based on understanding of intratumoral T-cell differentiation originating from stem-like CD8T cellsPrincipal Investigator

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Development of new cancer immunotherapy that targets the CD69-Myl9/12 systemPrincipal Investigator

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Development of novel treatment strategies targeting the R-spondin-LGR-APC axis in glioblastoma stem cellsPrincipal Investigator

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Development of therapy that targets ovarian clear cell carcinoma stem cellsPrincipal Investigator

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Study of the function of the nuclear protein LDOC1 in the regulation of MDM2-mediated p53 ubiquitinationPrincipal Investigator

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Study on the function of the transcriptional repressor Fbl10 in the regulation of c-JunPrincipal Investigator

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Molecular mechanism of tumor cell growth

Principal Investigator

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Research Institution

[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023

Author(s)

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Data Source

[Journal Article] CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes2023

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[Journal Article] CD69 imposes tumor-specific CD8+ T cell fate in tumor-draining lymph nodes2023

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[Journal Article] The cellular and molecular basis of CD69 function in anti-tumor immunity2022

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[Journal Article] IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation2021

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Nasu Ryo 那須亮

NASU Ryo 那須亮