okada mami 岡田麻美

… Alternative Names

Okada-Tsuchioka Mami 岡田麻美

OKADA-TSUCHIOKA Mami 岡田麻美

OKADA Mami 岡田麻美

土岡麻美

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Researcher Number	30517280
Other IDs
Affiliation (Current)	2025: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, 研究員(移行)
Affiliation (based on the past Project Information) *help	2016 – 2024: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, 研究員(移行) 2017: 国立病院機構呉医療センター, 中国がんセンター臨床研究部, 研究員 2012 – 2014: 独立行政法人国立病院機構(呉医療センター臨床研究部), その他部局等, 研究員 2010: 国立病院機構呉医療センター, 臨床研究部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 52030:Psychiatry-related / Biological pharmacy Except Principal Investigator Psychiatric science / Basic Section 21030:Measurement engineering-related
Keywords	Principal Investigator うつ病 / アストロサイト / 精神神経科学 / エクソソーム / thrombospondin-1 / 電気けいれん療法 / シナプス新生 / プロテオミクス / 脳組織 / sEV … More / バイオマーカー / リキッドバイオプシー / トランスレーショナルリサーチ / Thrombospondin-1 … More Except Principal Investigator アストロサイト / グリア / 抗うつ薬 / DNA分解酵素 / インピーダンス計測 / 交流電気浸透 / 生体分子 / 誘電泳動 / リゾホスファチジン酸受容体１ / 抗うつ薬受容体 / うつ病 / プロテオミクス / 繊維芽細胞成長因子受容体 / アフィニティクロマトグラフィ / 神経栄養因子 / 精神薬理学 Less

脳組織中細胞外小胞のプロテオミクスによる新規うつ病関連分子の探索と臨床への応用Principal Investigator
- Principal Investigator
  
  岡田麻美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
DNA修飾粒子を用いたDNA分解酵素検出法の開発
- Principal Investigator
  
  江口正徳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 21030:Measurement engineering-related
- Research Institution
  National Institute of Technology (KOSEN), Kure College
脳由来エクソソームの細胞種特異的・高感度回収技術の構築とうつ病バイオマーカー探索Principal Investigator
- Principal Investigator
  
  岡田麻美
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
An Exploratory research on biomarkers of depression based on astrocyte-derived exosomesPrincipal Investigator
- Principal Investigator
  
  Okada-Tsuchioka Mami
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Study on the astrocyte-derived TSP-1 as an ECT target molecule of refractory depression.Principal Investigator
- Principal Investigator
  
  Okada-Tsuchioka Mami
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
A pharmacological and clinical study of G protein-coupled antidepressant receptors on astrocytes
- Principal Investigator
  
  Takebayashi Minoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Investigation of the thrombospondin-1 as a novel therapeutic target molecule for depression.Principal Investigator
- Principal Investigator
  
  OKADA-TSUCHIOKA Mami
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Department of Clinical Research, National Hospital Organization Kure Medical Center
Identification of novel targets related to induce expression of neurotrophic factors at antidepressant in glia
- Principal Investigator
  
  TAKEBAYASHI Minoru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  国立病院機構呉医療センター精神科
   Department of Clinical Research, National Hospital Organization Kure Medical Center

[Journal Article] Tetraspanin heterogeneity of small extracellular vesicles in human biofluids and brain tissue2022
- Author(s)
  Okada-Tsuchioka Mami、Kajitani Naoto、Omori Wataru、Kurashige Takashi、Boku Shuken、Takebayashi Minoru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 627 Pages: 146-151
- DOI
  10.1016/j.bbrc.2022.08.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07501, KAKENHI-PROJECT-21K07536, KAKENHI-PROJECT-18H02756
[Journal Article] Differential anatomical and cellular expression of lysophosphatidic acid receptor 1 in adult mouse brain2020
- Author(s)
  Kajitani Naoto、Okada-Tsuchioka Mami、Kano Kuniyuki、Omori Wataru、Boku Shuken、Aoki Junken、Takebayashi Minoru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 531 Issue: 2 Pages: 89-95
- DOI
  10.1016/j.bbrc.2020.05.068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02756, KAKENHI-PROJECT-18K07620
[Journal Article] Lysophosphatidic acid induces thrombospondin‐1 production in primary cultured rat cortical astrocytes2020
- Author(s)
  Hisaoka‐Nakashima Kazue、Yokoe Toshiki、Watanabe Shintaro、Nakamura Yoki、Kajitani Naoto、Okada‐Tsuchioka Mami、Takebayashi Minoru、Nakata Yoshihiro、Morioka Norimitsu
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: in press Issue: 4 Pages: 849-864
- DOI
  10.1111/jnc.15227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02756, KAKENHI-PROJECT-18K07620
[Journal Article] Shared preventive factors associated with relapse after a response to electroconvulsive therapy in four major psychiatric disorders.2019
- Author(s)
  Omori Wataru、Itagaki Kei、Kajitani Naoto、Abe Hiromi、Okada‐Tsuchioka Mami、Okamoto Yasumasa、Takebayashi Minoru
- Journal Title
  
  Psychiatry and Clinical Neurosciences
  
  Volume: 印刷中 Issue: 8 Pages: 494-500
- DOI
  10.1111/pcn.12859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07620, KAKENHI-PROJECT-18K15534
[Journal Article] Antidepressant amitriptyline‐induced matrix metalloproteinase‐9 activation is mediated by Src family tyrosine kinase, which leads to glial cell line‐derived neurotrophic factor mRNA expression in rat astroglial cells.2019
- Author(s)
  Abe Hiromi、Kajitani Naoto、Okada‐Tsuchioka Mami、Omori Wataru、Yatsumoto Masahide、Takebayashi Minoru
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 印刷中 Issue: 3 Pages: 156-163
- DOI
  10.1002/npr2.12055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07620, KAKENHI-PROJECT-18K15534, KAKENHI-PROJECT-18H02756
[Journal Article] Decreased serum levels of thrombospondin‐1 in female depressed patients2019
- Author(s)
  Okada‐Tsuchioka Mami、Omori Wataru、Kajitani Naoto、Shibasaki Chiyo、Itagaki Kei、Takebayashi Minoru
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 40 Issue: 1 Pages: 39-45
- DOI
  10.1002/npr2.12088
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07620, KAKENHI-PROJECT-18K15534
[Journal Article] Possible Association between Serum Matrix Metalloproteinase-9 (MMP-9) Levels and Relapse in Depressed Patients following Electroconvulsive Therapy (ECT)2017
- Author(s)
  Shibasaki Chiyo、Itagaki Kei、Abe Hiromi、Kajitani Naoto、Okada-Tsuchioka Mami、Takebayashi Minoru
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume: 21 Issue: 3 Pages: 236-241
- DOI
  10.1093/ijnp/pyx086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18883, KAKENHI-PROJECT-16K19796
[Journal Article] Factors associated with relapse after a response to electroconvulsive therapy in unipolar versus bipolar depression.2017
- Author(s)
  Itagaki K, Takebayashi M, Shibasaki C, Kajitani N, Abe H, Okada-Tsuchioka M, Yamawaki S.
- Journal Title
  
  Journal of Affective Disorders.
  
  Volume: 208 Pages: 113-119
- DOI
  10.1016/j.jad.2016.08.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K18883, KAKENHI-PROJECT-16K19796
[Journal Article] The expression of glial cell line-derived neurotrophic factor mRNA by antidepressants involves matrix metalloproteinase-9 activation in rat astroglial cells2016
- Author(s)
  Abe H, Hisaoka-Nakashima K, Kajitani N, Okada-Tsuchioka M, Yano R, Itagaki K, Shibasaki C, Morioka N, Nakata Y, Takebayashi M
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 479 Issue: 4 Pages: 907-912
- DOI
  10.1016/j.bbrc.2016.09.070
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09819, KAKENHI-PROJECT-16K08270, KAKENHI-PROJECT-16K18883, KAKENHI-PROJECT-16K19796
[Journal Article] Altered serum levels of matrix metalloproteinase-2, -9 in response to electroconvulsive therapy for mood disorders2016
- Author(s)
  Shibasaki C, Takebayashi M, Itagaki K, Abe H, Kajitani N, Okada-Tsuchioka M, Yamawaki S
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume: 19 Issue: 9 Pages: pyw019-pyw019
- DOI
  10.1093/ijnp/pyw019
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09819
[Journal Article] Identification of lysophosphatidic acid receptor 1 in astroglial cells as a target for glial cell line-derived neurotrophic factor expression induced by antidepressants.2016
- Author(s)
  Kajitani, N., Miyano, K., Okada-Tsuchioka, M., Abe, H., Itagaki, K., Hisaoka-Nakashima, K., Morioka, N., Uezono, Y., Takebayashi, M.
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 53 Pages: 27364-27370
- DOI
  10.1074/jbc.m116.753871
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08686, KAKENHI-PROJECT-15K09819, KAKENHI-PROJECT-16K08270, KAKENHI-PROJECT-16K18883, KAKENHI-PROJECT-16K19796
[Journal Article] Fibroblast growth factor 2 mRNA expression evoked by amitriptyline involves ERK-dependent EGR1 production in rat primary cultured astrocytes2015
- Author(s)
  Kajitani N, Hisaoka-Nakashima K, Okada-Tsuchioka M, Hosoi M,Yokoe T, Morioka N, Nakata Y , Takebayashi M
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 135 Pages: 27-37
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09819
[Journal Article] ricyclic antidepressant amitriptyline-induced glial cell line-derived neurotrophic factor production involves pertussis toxin-sensitive Gi/oactivation in astroglial cells2015
- Author(s)
  Hisaoka-Naashima K, Miyano K, Matsumoto C, Kajitani N , Abe H, Okada-Tsuchioka M, Yokoyama A, Uezono Y, Morioka N, Nakata Y, Takebayashi M
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 290 Pages: 13678-13691
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09819
[Journal Article] Electroconvulsive seizure induces thrombospondin-1 in the adult rat hippocampus.2014
- Author(s)
  Mami Okada-Tsuchioka, Masahiro Segawa, Naoto Kajitani, Kazue Hisaoka-Nakashima, Chiyo Shibasaki, Shigeru Morinobu, Minoru Takebayashi
- Journal Title
  
  Progress in Neuro-Psychopharmacology & Biological Psychiatry
  
  Volume: 48 Pages: 236-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790106
[Journal Article] 中枢神経系におけるtransactivation機構の情報伝達系としての役割2009
- Author(s)
  土岡麻美
- Journal Title
  
  日本神経精神薬理学雑誌
  
  Volume: 21 Pages: 91-97
- NAID
  10025185761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591384
[Patent] ビオチン誘導体又はその生理学的に許容される塩、その製造方法及びそれを用いたアフィニティクロマトグラフィ用材並びにタンパク質の分離方法2008
- Inventor(s)
  竹林実、土岡麻美
- Industrial Property Rights Holder
  竹林実、土岡麻美
- Industrial Property Number
  2008-335333
- Filing Date
  2008-12-26
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] AC-Electroosmosis Based Device for Collection of Extracellular Vesicles2023
- Author(s)
  Ibuki Machi, Taisuke Motoyama, Mami Okada, Naoto Kajitani, and Masanori Eguchi
- Organizer
  The 1st KOSEN Research International Symposium (KRIS)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K04148
[Presentation] AC-Electroosmosis Based Device for Collection of Extracellular Vesicles2023
- Author(s)
  Ibuki Machi, Taisuke Motoyama, Mami Okada, Naoto Kajitani, and Masanori Eguchi
- Organizer
  The 1st KOSEN Research International Symposium (KRIS)
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] A Development of EVs Detection Device Based on AC Electroosmosis2023
- Author(s)
  Ibuki Machi, Masanori Eguchi, Shinichi Tanaka, Mami Okada, and Naoto Kajitani
- Organizer
  Molecular Plasmonics 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] A Development of EVs Detection Device Based on AC Electroosmosis2023
- Author(s)
  Ibuki Machi, Masanori Eguchi, Shinichi Tanaka, Mami Okada, and Naoto Kajitani
- Organizer
  Molecular Plasmonics 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K04148
[Presentation] ヒト生体液および脳組織由来小型細胞外小胞におけるテトラスパニン不均一性の検討2023
- Author(s)
  岡田麻美、梶谷直人、大盛　航、倉重毅志、町野彰彦、朴　秀賢、竹林　実
- Organizer
  第10回日本細胞外小胞学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] 交流電界を用いた生体細胞と細胞外小胞の分離2022
- Author(s)
  甲斐萌華，町依蕗，江口正徳，岡田麻美，梶谷直人
- Organizer
  化学とマイクロ・ナノシステム学会第46回研究会（CHEMINAS 46）
- Data Source
  KAKENHI-PROJECT-22K04148
[Presentation] 交流電気浸透流を用いたエクソソーム収集デバイスの開発2022
- Author(s)
  町　依蕗，二重谷　光輝，甲斐　萌華，中岡　佑輔，江口　正徳，岡田　麻美，梶谷　直人
- Organizer
  第34回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-22K04148
[Presentation] 交流電界を用いた生体細胞と細胞外小胞の分離2022
- Author(s)
  甲斐萌華，町依蕗，江口正徳，岡田麻美，梶谷直人
- Organizer
  化学とマイクロ・ナノシステム学会第46回研究会（CHEMINAS 46）
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] 交流電気浸透流を用いたエクソソーム収集デバイスの開発2022
- Author(s)
  町　依蕗，二重谷　光輝，甲斐　萌華，中岡　佑輔，江口　正徳，岡田　麻美，梶谷　直人
- Organizer
  第34回バイオエンジニアリング講演会
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] 誘電泳動現象を用いた生体細胞単離法に関する研究2021
- Author(s)
  中岡佑輔、岡田麻美、梶谷直人、江口正徳
- Organizer
  化学とマイクロ・ナノシステム学会第43回研究会（CHEMINAS 43）
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] Development of rapid technology of Antigen-Antibody reaction by employing Dielectrophoresis.2021
- Author(s)
  中岡佑輔、岡田麻美、梶谷直人、江口正徳
- Organizer
  第31回日本MRS年次大会(MRSJ2021)
- Data Source
  KAKENHI-PROJECT-21K07536
[Presentation] 血清トロンボスポンジン-1（TSP-1）は女性うつ病患者において減少する2020
- Author(s)
  岡田麻美、大盛　航、梶谷直人、柴崎千代、板垣　圭、町野彰彦、竹林　実
- Organizer
  第50回日本神経精神薬理学会年会　第42会日本生物学的精神医学会年会　第4回日本精神薬学会総会・学術集会　NPBPPP2020合同年会 ONLINE
- Data Source
  KAKENHI-PROJECT-18K07620
[Presentation] 血清トロンボスポンジン-1(TSP-1)は女性うつ病患者において減少する2019
- Author(s)
  岡田麻美、大盛　航、梶谷直人、柴崎千代、板垣　圭、町野彰彦、竹林　実
- Organizer
  第38回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-18K07620
[Presentation] グリアにおける抗うつ薬受容体としてのLPA1の可能性-抗うつ薬のLPA1への直接作用に関する検討-2018
- Author(s)
  岡田麻美、宮野加奈子、梶谷直人、安部裕美、大盛　航、板垣　圭、上園保仁、竹林　実
- Organizer
  第5回サイコグリア研究会
- Data Source
  KAKENHI-PROJECT-18K07620
[Presentation] Identification of lysophosphatidic acid receptor 1 in astrocytes as a target for glial cell line-derived neurotrophic factor expression induced by antidepressants2017
- Author(s)
  Kajitani N, Miyano K, Okada-Tsuchioka M, Abe H, Omori W, Itagaki K, Uezono Y, Takebayashi M
- Organizer
  47th Annual Meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] アストロサイトを標的とした新たな抗うつ薬の作用点としてのLPA1の可能性2017
- Author(s)
  岡田麻美、梶谷直人、宮野加奈子、安部裕美、大盛　航、板垣　圭、上園保仁、竹林　実
- Organizer
  第36回躁うつ病の薬理・生化学的研究懇話会
- Data Source
  KAKENHI-PROJECT-16K18883
[Presentation] Reduced serum and cerebrospinal fluid levels of autotaxin in major depressive disorder2017
- Author(s)
  Itagaki K, Abe H, Shibasaki C, Omori W, Kajitani N, Abe H, Okada-Tsuchioka M, Hattori K, Yoshida S, Kunugi H, Takebayashi M
- Organizer
  47th Annual Meeting of Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] Antidepressant amitriptyline activates matrix metalloproteinase in astroglial cells: involvement in glial cell line-derived neurotrophic factor expression2016
- Author(s)
  Abe H, Hisaoka-Nakashima K, Kajitani N, Okada-Tsuchioka, Itagaki K, Shibasaki C, Morioka N, Nakata Y, Takebayashi M
- Organizer
  30th CINP World Congress of Neuropsychopharmacology
- Place of Presentation
  ソウル
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] グリアから謎解く精神疾患のトランスレーショナルリサーチ研究　～気分障害とアストロサイトの観点から～2016
- Author(s)
  竹林　実, 岡田麻美, 柴崎千代, 板垣　圭, 梶谷直人, 安部裕美, 宮野加奈子, 中島一恵, 森岡徳光, 上園保仁
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学学会大会　合同大会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] Antidepressants activate matorix metalloprotease (MMP) in astroglial cells: involvement in glial cell line-derived neurotrophic factor (GDNF) expression.2015
- Author(s)
  Abe H, Hisaoka-Nakashima K, Kajitani N, Okada-Tsuchioka, Itagaki K, Morioka N, Nakata Y, Takebayashi M
- Organizer
  45th Annual Meeting of Society for Neuroscience
- Place of Presentation
  アメリカ　シカゴ
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] 気分障害のマトリックスメタロプロテアーゼ（MMP）に着目したバイオマーカーおよび創薬に向けた研究2015
- Author(s)
  竹林　実、柴崎千代、安部裕美、板垣　圭、梶谷直人、岡田麻美、中島一恵、森岡徳光、仲田義啓
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同大会
- Place of Presentation
  東京
- Year and Date
  2015-09-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K09819
[Presentation] 電気けいれん刺激(ECS)は成体ラット海馬においてシナプス新生作用を有するアストロサイト分泌性thrombospondin-1(TSP-1)を誘導する2013
- Author(s)
  岡田（土岡）麻美、瀬川昌弘、梶谷直人、柴崎千代、安部裕美、中島（久岡）一恵、森信　繁、竹林　実
- Organizer
  第23回日本臨床精神神経薬理学会・第43回日本神経精神薬理学会合同年会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Data Source
  KAKENHI-PROJECT-24790106
[Presentation] リルゾールはグリア細胞において繊維芽細胞増殖因子受容体(FGFR)を介してグリア細胞株由来神経栄養因子(GDNF)を産生する2010
- Author(s)
  土岡麻美、久岡一恵、矢野遼也、梶谷直人、竹林実
- Organizer
  第29回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] 抗うつ薬はラット初代培養アストロサイトにおいてFGF-2の発現を増加させる2010
- Author(s)
  梶谷直人、久岡一恵、森岡徳光、土岡麻美、矢野遼也、竹林実、仲田義啓
- Organizer
  第13回創薬・薬理フォーラム岡山
- Place of Presentation
  広島
- Year and Date
  2010-08-11
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] 抗うつ薬はグリアにおいてFGF受容体を活性化してGDNFを産生する2010
- Author(s)
  久岡一恵、竹林実、土岡麻美、矢野遼也、梶谷直人、森岡徳光、仲田義啓
- Organizer
  第117回日本薬理学会近畿部会
- Place of Presentation
  徳島
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] ラット初代培養アストロサイトにおいて抗うつ薬が神経栄養因子・成長因子の発現に及ぼす影響2010
- Author(s)
  梶谷直人、久岡一恵、森岡徳光、土岡麻美、朴秀賢、中川伸、仲田義啓、竹林実
- Organizer
  第29回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] ラット初代培養アストロサイトにおいて抗うつ薬はFGF-2の発現を増加させる2009
- Author(s)
  梶谷直人、久岡一恵、森岡徳光、中村明陽、土岡麻美、朴秀賢、中川伸、仲田義啓、竹林実
- Organizer
  第19回日本臨床精神神経薬理学会・第39回日本神経精神薬理学会合同大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] グリアにおける抗うつ薬の新規ターゲット分子同定の試み2009
- Author(s)
  土岡麻美、久岡一恵、仲田義啓、竹林実
- Organizer
  第28回躁うつ病の薬理・生化学的研究懇話会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] 抗うつ薬はFGF受容体を介してグリアからのGDNF産生を誘導する2008
- Author(s)
  久岡一恵、土岡麻美、長島悟史、藤田康孝、竹林実
- Organizer
  第18回日本臨床精神神経薬理学会・第38回日本神経精神薬理学会合同年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591384
[Presentation] How does electroconvulsive therapy work for depression? -Involvement of astrocyte-derived synaptogenic factor, thrombospondin-1-
- Author(s)
  Mami Okada-Tsuchioka, Naoto Kajitani, Hiromi Abe, Chiyo Shibasaki, Minoru Takebayashi
- Organizer
  The 7th Kure International Medical Forum (K-INT) in 2014
- Place of Presentation
  Convention Hall, National Hospital Organization, Kure Medical Center Chugoku Cancer Center
- Year and Date
  2014-07-10 – 2014-07-13
- Data Source
  KAKENHI-PROJECT-24790106
[]
[]

1. TAKEBAYASHI Minoru (60304440)

# of Collaborated Projects: 2 results

# of Collaborated Products: 19 results
2. HISAOKA Kazue (20393431)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 江口正徳 (60613594)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. NAKATA Yoshihiro (40133152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
5. MIYANO KANAKO (50597888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. HASHIMOTO ERI (30301401)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. UKAI WATARU (40381256)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 上園保仁 (20213340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. 梶谷直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

okada mami 岡田 麻美

Okada-Tsuchioka Mami 岡田 麻美

OKADA-TSUCHIOKA Mami 岡田 麻美

OKADA Mami 岡田 麻美

土岡 麻美

Research Projects

Research Products

Co-Researchers

脳組織中細胞外小胞のプロテオミクスによる新規うつ病関連分子の探索と臨床への応用Principal Investigator

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DNA修飾粒子を用いたDNA分解酵素検出法の開発

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脳由来エクソソームの細胞種特異的・高感度回収技術の構築とうつ病バイオマーカー探索Principal Investigator

Principal Investigator

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An Exploratory research on biomarkers of depression based on astrocyte-derived exosomesPrincipal Investigator

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Study on the astrocyte-derived TSP-1 as an ECT target molecule of refractory depression.Principal Investigator

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A pharmacological and clinical study of G protein-coupled antidepressant receptors on astrocytes

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Investigation of the thrombospondin-1 as a novel therapeutic target molecule for depression.Principal Investigator

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Identification of novel targets related to induce expression of neurotrophic factors at antidepressant in glia

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[Journal Article] Tetraspanin heterogeneity of small extracellular vesicles in human biofluids and brain tissue2022

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[Journal Article] Differential anatomical and cellular expression of lysophosphatidic acid receptor 1 in adult mouse brain2020

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[Journal Article] Lysophosphatidic acid induces thrombospondin‐1 production in primary cultured rat cortical astrocytes2020

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[Journal Article] Shared preventive factors associated with relapse after a response to electroconvulsive therapy in four major psychiatric disorders.2019

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[Journal Article] Antidepressant amitriptyline‐induced matrix metalloproteinase‐9 activation is mediated by Src family tyrosine kinase, which leads to glial cell line‐derived neurotrophic factor mRNA expression in rat astroglial cells.2019

Author(s)

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DOI

okada mami 岡田麻美

Okada-Tsuchioka Mami 岡田麻美

OKADA-TSUCHIOKA Mami 岡田麻美

OKADA Mami 岡田麻美

土岡麻美