Menjyu Toshi 毛受暁史

… Alternative Names

MENJYU Toshi 毛受暁史

毛受暁史メンジュトシ

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Researcher Number	30527081
Other IDs	https://orcid.org/0000-0002-7341-6002
Affiliation (Current)	2024: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 京都大学, 医学研究科, 准教授 2018 – 2019: 京都大学, 医学研究科, 講師 2018: 京都大学, 医学研究科, 特定病院助教 2017: 京都大学, 医学(系)研究科(研究院), その他 2016: 京都大学, 医学研究科, 特定病院助教 … More 2014 – 2016: 京都大学, 医学(系)研究科(研究院), 助教 2015: 京都大学, 大学院医学研究科, 助教 2013: 京都大学, 医学(系)研究科 2010: 京都大学, 医学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Respiratory surgery / Basic Section 55040:Respiratory surgery-related Except Principal Investigator Respiratory surgery / General surgery / Thoracic surgery / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Keywords	Principal Investigator EGFR / 浸潤転移 / 肺癌 / 上皮間葉転換 / 浸潤転移能 / Grb2 / GEP100 / Arf6 / EMT / スタチン … More / 変異p53 / 上皮間葉転換　（EMT) / 薬剤耐性 / p53 / 肺癌悪性化 / 変異p53誘導 / 上皮間葉転換（EMT) / RNA-seq / p53変異 / 薬剤スクリーニング / Transgenic mouse / 上皮間葉転換（EMT） / p53遺伝子変異 / Arf6活性化 / 予後不良 / EPB41L5 / AMAP1 / EGFR陽性肺腺癌 / ＥＭＴ / 肺腺癌 / Ｇｒｂ２ / Ａｒｆ６ / ＧＥＰ１００ / ＥＧＦＲ / 上皮間葉転換、ＥＭＴ / アダプター分子 … More Except Principal Investigator 肺癌 / 遺伝子発現 / 治療 / シグナル経路 / 上皮間葉転換 / 変異型p５３ / 上皮間葉転換（EMT / 浸潤転移 / 変異型p53遺伝子 / スタチン / EGFR / 上皮間葉転換（EMT） / p53 / Focal Adhesion Pathway / 薬剤耐性 / 耐性化メカニズム / ビノレルビン / 薬剤耐性化株 / FA PatHway / クラスター解析 / コピー数異常 / 胸腺腫瘍 / コピー数 / 胸腺上皮性腫瘍 / DNAコピー数変化 / トランスクリプトーム / 胸腺癌 / PC14 / H460 / Lewis株 / HARA細胞 / in vivo selection法 / 特異的抗体 / EMT / 肺癌転移能 / Kinome / 粘膜免疫 / 制御性T細胞 / 癌ワクチン / 癌免疫 / 悪性化進展 / 線維芽細胞 / リンパ節転移モデル / 移植免疫 / 抗体関連拒絶 / 抗ドナー特異抗体 / リンパ組織新生 / BOS / RAS / 慢性拒絶 / 肺移植 / sh RNA / ｓｈＲＮＡ / ＦＧＦＲ / shRNA / 遺伝子治療 / ベクター / アデノウィルス / ｓｈRNA / FGFR / 融合遺伝子 / ALK / 腺癌 / 原発性肺癌 Less

The elucidation of mechanisms and the development of novel therapeutic methods for mutant p53-induced EMT in lung cancerPrincipal Investigator
- Principal Investigator
  
  毛受暁史
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Kyoto University
The elucidation of key signaling pathways and the establishment of treatment strategies for mutant p53-induced epithelio-mesenchymal transition in lung cancer
- Principal Investigator
  
  Date Hiroshi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyoto University
The elucidation of the novel therapy specific for lung cancer targeting Arf6-induced EMTPrincipal Investigator
- Principal Investigator
  
  Menju Toshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
The elucidation of the clinical significance and the mechanisms of acquired drug resistance with activated FA pathway in cancer cells
- Principal Investigator
  
  園部誠
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
Comprehensive analyses of transcriptome and DNA copy number variations in thymic cancer
- Principal Investigator
  
  Date Hiroshi
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
The impact of locally produced anti-donor specific antibody in de novo intrapulmonary lymphoid tissue on RAS, the sever form of chronic rejection after lung transplantation
- Principal Investigator
  
  Sato Masaaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
  Kyoto University
The identification of targeting molecules for EMT-activating signals from ErbB family receptor in lung cancerPrincipal Investigator
- Principal Investigator
  
  MENJU Toshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
臨床と基礎をつなぐ視点からの肺癌悪性化進展における繊維芽細胞、繊維化の役割解明
- Principal Investigator
  
  大政貢
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
Cancer inhalation therapy: a novel platform for cancer vaccine utilizing the mucosal immune system in the airways
- Principal Investigator
  
  Sato Masaaki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  The University of Tokyo
  Kyoto University
Comprehensive kinome analysis of metastatic activity in lung cancer cells
- Principal Investigator
  
  DATE Hiroshi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory surgery
- Research Institution
  Kyoto University
Gene therapy using FGFR-inhibiting vector against lung squamous cell carcinoma
- Principal Investigator
  
  DATE Horoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
Detection of new fusion partner genes with ALK gene
- Principal Investigator
  
  SONOBE Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University

All 2023 2022 2021 2019 2018 2017 2016 2015 2014 2012 2011 2010

All Journal Article Presentation

[Journal Article] A novel cell-based assay for the high-throughput screening of epithelial?mesenchymal transition inhibitors: Identification of approved and investigational drugs that inhibit epithelial?mesenchymal transition2023
- Author(s)
  Ishikawa Hiroyuki、Menju Toshi、Toyazaki Toshiya、Miyamoto Hideaki、Chiba Naohisa、Noguchi Misa、Tamari Shigeyuki、Miyata Ryo、Yutaka Yojiro、Tanaka Satona、Yamada Yoshito、Nakajima Daisuke、Ohsumi Akihiro、Hamaji Masatsugu、Okuno Yukiko、Date Hiroshi
- Journal Title
  
  Lung Cancer
  
  Volume: 175 Pages: 36-46
- DOI
  10.1016/j.lungcan.2022.11.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03770
[Journal Article] Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor2022
- Author(s)
  Miyata Ryo、Hasegawa Koichi、Menju Toshi、Yoshizawa Akihiko、Watanabe Akira、Hirai Toyohiro、Date Hiroshi、Sato Atsuyasu
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 9 Pages: 104912-104912
- DOI
  10.1016/j.isci.2022.104912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03770
[Journal Article] Nrf2/p?Fyn/ABCB1 axis accompanied by p?Fyn nuclear accumulation plays pivotal roles in vinorelbine resistance in non?small cell lung cancer2022
- Author(s)
  Tamari Shigeyuki、Menju Toshi、Toyazaki Toshiya、Miyamoto Hideaki、Chiba Naohisa、Noguchi Misa、Ishikawa Hiroaki、Miyata Ryo、Kayawake Hidenao、Tanaka Satona、Yamada Yoshito、Yutaka Yojiro、Nakajima Daisuke、Ohsumi Akihiro、Hamaji Masatsugu、Date Hiroshi
- Journal Title
  
  Oncology Reports
  
  Volume: 48 Issue: 4 Pages: 1-5
- DOI
  10.3892/or.2022.8386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03770
[Journal Article] High programmed death ligand 1 expression in carcinomatous components predicts a poor prognosis in pulmonary pleomorphic carcinoma2022
- Author(s)
  Noguchi Misa、Menju Toshi、Nakajima Naoki、Yoshizawa Akihiko、Ohsumi Akihiro、Nakajima Daisuke、Hamaji Masatsugu、Haga Hironori、Date Hiroshi
- Journal Title
  
  Surgery Today
  
  Volume: 52 Issue: 7 Pages: 1090-1095
- DOI
  10.1007/s00595-021-02439-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03770
[Journal Article] Lung cancer and epithelial-mesenchymal transition2021
- Author(s)
  Toshi Menju, Hiroshi Date
- Journal Title
  
  General Thoracic and Cardiovascular Surgery
  
  Volume: 5 Issue: 5 Pages: 781-789
- DOI
  10.1007/s11748-021-01595-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03770
[Journal Article] Prognostic impact of microscopic vessel invasion and visceral pleural invasion and their correlations with epithelial-mesenchymal transition, cancer stemness, and treatment failure in lung adenocarcinoma.2019
- Author(s)
  Neri, S., T. Menju, T. Sowa, Y. Yutaka, D. Nakajima, M. Hamaji, A. Ohsumi, T. F. Chen-Yoshikawa, T. Sato, M. Sonobe, A. Yoshizawa, H. Haga and H. Date
- Journal Title
  
  Lung Cancer
  
  Volume: 128 Pages: 13-19
- DOI
  10.1016/j.lungcan.2018.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10781, KAKENHI-PROJECT-18K19578
[Journal Article] The Ratios of monounsaturated to saturated phosphatidylcholines in lung adenocarcinoma microenvironment analyzed by Liquid Chromatography-Mass spectrometry and imaging Mass spectrometry.2019
- Author(s)
  Muranishi, Y., T. Sato, S. Ito, J. Satoh, A. Yoshizawa, S. Tamari, Y. Ueda, Y. Yutaka, T. Menju, T. Nakamura and H. Date
- Journal Title
  
  Scientific Reports
  
  Volume: 1 Issue: 1 Pages: 8916-8916
- DOI
  10.1038/s41598-019-45506-3
- NAID
  120006777029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10781, KAKENHI-PROJECT-18K19578
[Journal Article] P40 expression in small cell lung cancer: The presence of p40-positive cells does not always indicate squamous differentiation.2019
- Author(s)
  Nakajima, N., A. Yoshizawa, K. Moriyoshi, M. Sonobe, T. Menju, S. Sumiyoshi, H. Date and H. Haga
- Journal Title
  
  Thoracic Cancer
  
  Volume: 11 Issue: 5 Pages: 3410-3432
- DOI
  10.1111/1759-7714.13062
- NAID
  120006624101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10781
[Journal Article] Prognostic Significance of Phosphorylated Fyn in Patients with Lung Adenocarcinoma after Lung Resection2019
- Author(s)
  Nishikawa S, Menju T, Takahashi K, Miyata R, Sonobe M, Yoshizawa A, Date H
- Journal Title
  
  ATCS
  
  Volume: 25 Issue: 5 Pages: 246-252
- DOI
  10.5761/atcs.oa.19-00078
- NAID
  130007731493
- ISSN
  1341-1098, 2186-1005
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10781
[Journal Article] Prognostic Significance of Phosphorylated Fyn in Patients with Lung Adenocarcinoma after Lung Resection.2019
- Author(s)
  Nishikawa, S., T. Menju, K. Takahashi, R. Miyata, M. Sonobe, A. Yoshizawa and H. Date
- Journal Title
  
  Annals of Thoracic Cardiovascular Surgery
  
  Volume: 5 Pages: 246-252
- NAID
  130007731493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19578
[Journal Article] Statins may have double-edged effects in patients with lung adenocarcinoma after lung resection2019
- Author(s)
  Nishikawa Shigeto、Menju Toshi、Takahashi Koji、Miyata Ryo、Chen Yoshikawa Toyofumi Fengshi、Sonobe Makoto、Yoshizawa Akihiko、Sabe Hisataka、Sato Tosiya、Date Hiroshi
- Journal Title
  
  Cancer Management and Research
  
  Volume: Volume 11 Pages: 3419-3432
- DOI
  10.2147/cmar.s200819
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02608, KAKENHI-PROJECT-17K10781, KAKENHI-PROJECT-18K19578
[Journal Article] Adjuvant vinorelbine and cisplantin after complete resection of stage II and III non-small cell lung cancer: long-term follow-up of our study of Japanease patients.2018
- Author(s)
  371.Sonobe M, Hamaji M, Motoyama H, Menju T, Aoyama A, Chen-Yoshikawa TF, Sato T, Date H.
- Journal Title
  
  Surgery Today
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10782
[Journal Article] horacoscopic rebiopsy to detect T790M mutation after postoperative recurrence.2018
- Author(s)
  376.Hamaji M, Motoyama H, Menju T, Chen-Yoshikawa TF, Sonobe M, Kim YH, Date H.
- Journal Title
  
  Interact Cardiovasc Thorac Surg
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10782
[Journal Article] Second malignancy versus recurrence after complete resection of thymoma.2018
- Author(s)
  373.Hamaji M, Sozu T, Machida R, Omasa M, Menju T, Aoyama A, Sato T, Chen-Yoshikawa TF, Sonobe M, Date H.
- Journal Title
  
  Asian Cardiovasc Thorac Ann
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10782
[Journal Article] The synergistic role of ATP-dependent drug efflex pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer.2018
- Author(s)
  368.Nakanishi T, Menju T, Nishikawa S, Takahashi K, Miyata R, Shikuma K, Sowa T, Imamura N, Hamaji M, Motoyama H, Hijiya K, Aoyama A, Sato T, Chen-Yoshikawa TF, Sonobe M, Date H.
- Journal Title
  
  Cancer Medicne
  
  Volume: 7(2) Pages: 408-19
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10782
[Journal Article] Clinicopathologic significance of epithelio-mesenchymal transition in human lung adenocarcinomas: an integrative analysis, inclusive of genetic alterations, on 256 surgically resected cases2017
- Author(s)
  Toshi Menju, Terumasa Sowa, Makoto Sonobe, Ryo Miyata, Koji Takahashi, Shigeto Nishikawa, Takao Nakanishi, Shinya Neri1, Hiroyuki Cho1, Masatsugu Hamaji, Kyoko Hijiya, Hideki Motoyama, Akihiro Aoyama, Toyofumi F. Chen-Yoshikawa, Toshihiko Sato, Akihiko Yoshizawa, Hironori Haga, Hiroshi Date
- Journal Title
  
  Cancer Treatment and Research Communications
  
  Volume: 12 Pages: 62-68
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10781
[Journal Article] Association of Local Intrapulmonary Production of Antibodies Specific to Donor Major Histocompatibility Complex Class I with the Progression of Chronic Rejection of Lung Allografts.2017
- Author(s)
  Miyamoto E, Motoyama H, Sato M, Aoyama A, Menju T, Shikuma K, Sowa T, Yoshizawa A, Saito M, Takahagi A, Tanaka S, Takahashi M, Ohata K, Kondo T, Hijiya K, Chen-Yoshikawa TF, Date H.
- Journal Title
  
  Transplantation
  
  Volume: 印刷中 Issue: 5 Pages: e156-e165
- DOI
  10.1097/tp.0000000000001665
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293286, KAKENHI-PROJECT-17H01581, KAKENHI-PROJECT-15K10253
[Journal Article] The synergistic role of ATP-Dependent Drug efflux pnmp and focal adhesion signaling pathways in vinorelbine resistance in lung cancer2017
- Author(s)
  Takao Nakanishi,Toshi Menjyu, Makoto Sonobe, 　他14名
- Journal Title
  
  Cancer Medicine
  
  Volume: - Pages: 408-419
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10782
[Journal Article] Is volumetric 3-dimensional computed tomography useful to predict histological tumour invasiveness? Analysis of 211 lesions of cT1N0M0 lung adenocarcinoma.2016
- Author(s)
  Shikuma K, Menju T, Chen F, Kubo T, Muro S, Sumiyoshi S, Ohata K, Sowa T, Nanaknishi T, Cho H, Neri S, Aoyama A, Sato T, Sonobe M, Date H.
- Journal Title
  
  Interact Cardiovasc Thorac Surg
  
  Volume: 22(6) Pages: 831-8
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15636
[Journal Article] Surgical and non-surgical management of repeat pulmonary metastasis from sarcoma following first pulmonary metastatectomy.2016
- Author(s)
  Hamaji M, Chen F, Miyamoto E, Kondo T, Ohata K, Motoyama H, Hijiya K, Menju T, Aoyama A, Sato T, Sonobe M, Date H.
- Journal Title
  
  Surg Today
  
  Volume: 46(11) Pages: 1296-1300
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15636
[Journal Article] Trametinib plus 4-methylumbelliferone exhibits antitumor effects by ERK blockade and CD44 downregulation and affects PD1 and PD-L1 in malignant pleural mesothelioma.2016
- Author(s)
  Cho H, Matsumoto S, Fujita Y, Kuroda A, Menju T, Sonobe M, Kondo N, Torii I, Nakano T, Lara PN, Gandara DR, Date H, Hasegawa S.
- Journal Title
  
  J Thorac Oncol
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K15636
[Journal Article] UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1alpha2015
- Author(s)
  Goto Y, Zeng L, YeomCJ, Zhu Y, Morinibu A, Shinoyam K, Kobayashi M, Hirota K, Itasaka S, Yoshimura M, Tanimoto K, Sowa T, Menju T, Sonobe M, Kakeya H, Toi M, Date H, Hammond EM, Hiraoka M, Harada H.
- Journal Title
  
  Nat Commun
  
  Volume: 6 Issue: 1 Pages: 1-10
- DOI
  10.1038/ncomms7153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592322, KAKENHI-PROJECT-24592336, KAKENHI-PROJECT-24659563, KAKENHI-PROJECT-25861088, KAKENHI-PROJECT-26461886, KAKENHI-PROJECT-26462125, KAKENHI-PROJECT-26670555, KAKENHI-PROJECT-26670558, KAKENHI-PROJECT-26670693, KAKENHI-PROJECT-15K10551, KAKENHI-PROJECT-15K15577, KAKENHI-PROJECT-25462457, KAKENHI-PROJECT-26293276
[Journal Article] Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition.2014
- Author(s)
  Lin SH, Wang J, Saintigny P, Wu CC, Giri U, Zhang J, Menju T, Diao L, Byers L, Weinstein JN, Coombes KR, Girard L, Komaki R, Wistuba II, Date H, Minna JD, Heymach JV.
- Journal Title
  
  BMC Genomics
  
  Volume: Dec 8;15 Issue: 1 Pages: 1079-1079
- DOI
  10.1186/1471-2164-15-1079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462125
[Journal Article] A meta-analysis of debulking surgery versus surgical biopsy for unresectable thymoma.2014
- Author(s)
  Sato M, Aoyama A, Yamda T, Menjyu T, Chen F, Sato T, Sonobe M, Omasa M, Date H
- Journal Title
  
  Eur J Cardiovasc Surg
  
  Volume: Epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293286
[Journal Article] Virtual-assisted lung mapping: outcome of 100 consective cases in a single institute.2014
- Author(s)
  376.Sato M, Yamada T, Menju T, Aoyama A, Sato T, Chen F, Sonobe M, Omasa M, Date H.
- Journal Title
  
  Eur J Cardiovasc Surg
  
  Volume: Epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293286
[Journal Article] Indentification of subsets of patients with favorable prognosis after recurrence in completely resected non-small cell lung cancer.2014
- Author(s)
  335.Sonobe M, Yamada T, Sato M, Menju T, Aoyama A, Sato T, Chen F, Omasa M, Bando T, Date H.
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 21(8) Pages: 2546-54
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462125
[Journal Article] Impact of KRAS and EGFR gene mutations on recurrence and survival in patients with surgically resected lung adenocarcinomas2012
- Author(s)
  Sonobe M, Kobayashi M, Ishikawa M, Kikuchi R, Nakayama E, Takahashi T, Menju T, Takenaka K, Miyahara R, Huang CL, Okubo K, Bando T, Date H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 19 Suppl 3
- Data Source
  KAKENHI-PROJECT-23659666
[Journal Article] Intratumoral Wnt2B expression affects tumor proliferation and survival in malignant pleural mesothelioma patients2012
- Author(s)
  Kobayashi M, Huang CL, Sonobe M, Kikuchi R, Ishikawa M, Kitamura J, Miyahara R, Menju T, Iwakiri S, Itoi K, Yasumizu R, Date H
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 3 Pages: 952-958
- Data Source
  KAKENHI-PROJECT-23659666
[Journal Article] Expression of IGF1R is associated with tumor differentiation and survival in patients with lung adenocarcinoma2012
- Author(s)
  Kikuchi R, Sonobe M, Kobayashi M, Ishikawa M, Kitamura J, Nakayama E, Menju T, Miyahara R, Huang CL, Date H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 3 Pages: 412-420
- Data Source
  KAKENHI-PROJECT-23659666
[Journal Article] Clinicopathologic features of non-small cell lung cancer with EML4-ALK fusion gene2010
- Author(s)
  Takahashi T, Sonobe M, Kobayashi M, Yoshizawa A, Menju T, Nakayama E, Mino N, Iwakiri S, Sato K, Miyahara R, Okubo K, Manabe T, Date H
- Journal Title
  
  Ann Surg Oncol
  
  Volume: 17 Pages: 889-897
- NAID
  120002036596
- Data Source
  KAKENHI-PROJECT-22591563
[Presentation] Arf6-related Invasive Pathway Deteriorated Patients’ Prognosis in Mutant EGFR Lung Adenocarcinoma2019
- Author(s)
  Toshi Menju, Misa Noguchi, Shigeyuki Tamari, Hiroyuki Ishikawa, Ryo Miyata, Koji Takahashi, Shigeto Nishikawa, Satona Tanaka, Yoshito Yamada, Yojiro Yutaka, Daisuke Nakajima, Fengshi-Toyofumi Chen-Yoshikawa, Toshihiko Sato, Hiroshi Date
- Organizer
  WCLC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19578
[Presentation] 上皮間葉転換を標的とした肺癌新規治療法の開発2019
- Author(s)
  毛受暁史、西川滋人、曽和晃正２、千葉直久、宮本英明、玉里滋幸、野口未紗、石川浩之、宮田亮、伊達洋至
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19578
[Presentation] 上皮間葉転換を標的とした肺癌新規治療法の開発2019
- Author(s)
  毛受暁史、西川滋人、曽和晃正２、千葉直久、宮本英明、玉里滋幸、野口未紗、石川浩之、宮田亮、伊達洋至
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] 上皮間葉転換を標的とした肺癌新規治療法の開発2019
- Author(s)
  毛受暁史、西川滋人、曽和晃正、玉里滋幸、野口未紗、石川浩之、宮田亮、田中里奈、山田義人、豊洋次郎、中島大輔、大角明宏、濱路政嗣、佐藤寿彦、陳豊史、伊達洋至
- Organizer
  第72回日本胸部外科学会定期学術集会、
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] Arf6-related Invasive Pathway Deteriorated Patients’ Prognosis in Mutant EGFR Lung Adenocarcinoma2019
- Author(s)
  Toshi Menju, Misa Noguchi, Shigeyuki Tamari, Hiroyuki Ishikawa, Ryo Miyata, Koji Takahashi, Shigeto Nishikawa, Satona Tanaka, Yoshito Yamada, Yojiro Yutaka, Daisuke Nakajima, Fengshi-Toyofumi Chen-Yoshikawa, Toshihiko Sato, Hiroshi Date
- Organizer
  WCLC2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] 上皮間葉転換を標的とした肺癌新規治療法の開発2019
- Author(s)
  毛受暁史、西川滋人、曽和晃正、玉里滋幸、野口未紗、石川浩之、宮田亮、田中里奈、山田義人、豊洋次郎、中島大輔、大角明宏、濱路政嗣、佐藤寿彦、陳豊史、伊達洋至
- Organizer
  第72回日本胸部外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-18K19578
[Presentation] Suppression of mutant-p53-induced EMT by statins have double-edged effects on the patients with lung adenocarcinoma according to p53 mutation status2019
- Author(s)
  S.Nishikawa, T.Menju, T.Sowa, K.Takahashi, R.Miyata, H.Ishikawa, D.Nakajima, M.Hamaji, H.Motoyama, A.Aoyama, T.sato, F.Chen-Yoshikawa, M.Sonobe, H.Date
- Organizer
  American Association for Cancer Research, Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19578
[Presentation] Arf6-related Invasive Pathway Deteriorated Patients’ Prognosis in Mutant EGFR Lung Adenocarcinoma2018
- Author(s)
  Toshi Menjyu
- Organizer
  6th American Association for Cancer Research-Japanese Cancer Association Special Joint Conference, Poster
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] EGFR-Grb2結合は、GEP100-Arf6経路を介した肺癌浸潤転移能を亢進する2017
- Author(s)
  毛受暁史
- Organizer
  第76回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] EGFR-Grb2-GEP100 complex promoted its invasive and metastatic potential via Arf6 pathway in lung adenocarcinoma2017
- Author(s)
  Toshi Menjyu
- Organizer
  18th World Conference on Lung Cancer
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10781
[Presentation] GEP100-Arf6 pathway enhanced by Grb2 expression plays important roles for node-metastasis of lung cancer2016
- Author(s)
  毛受　暁史
- Organizer
  アメリカ癌学会
- Place of Presentation
  ニューオーリンズ、USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462125
[Presentation] GEP100-Arf6経路におけるGrb2アダプター分子の意義2016
- Author(s)
  毛受　暁史
- Organizer
  第３３回日本呼吸器外科学会総会
- Place of Presentation
  京都市、日本
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-26462125
[Presentation] GEP100-Arf6 pathway enhanced by Grb2 expression plays important roles for node-metastasis and EMT activation of lung cancer2016
- Author(s)
  毛受　暁史
- Organizer
  第２４回ヨーロッパ癌学会
- Place of Presentation
  マンチェスター、UK
- Year and Date
  2016-07-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462125
[Presentation] Grb2 promotes cancer invasiveness via EGF-induced GEP100-Arf6 pathway Grb2はEGF刺激によるGEP100-Arf6経路活性化を介した腫瘍浸潤転移能を促進する2015
- Author(s)
  Toshi Menju, Naoto Imamura, Shinya Neri, Hiroyuki Cho, Takao Nakanishi, Kei Shikuma, Terumasa Sowa, Makoto Sonobe, Hisataka Sabe, Hiroshi Date
- Organizer
  第１８回欧州癌治療学会
- Place of Presentation
  ウィーン、オーストリア
- Year and Date
  2015-09-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462125
[Presentation] Clinicopathological analysis on EMT activation in lung adenocarcinoma 肺腺癌切除検体におけるEMT活性化に伴う臨床病理学的解析2015
- Author(s)
  Toshi Menju, Terumasa Sowa, Shinya Neri, Takao Nakanishi, Hiroyuki Cho, Kei Shikuma, Kyoko Hijiya, Hideki Motoyama, Akihiro Aoyama, Fengshi Chen, Makoto Sonobe, Toshihiko Sato, Mitsugu Oomasa, *Akihiko Yoshizawa, *Hironori Haga, Hiroshi Date
- Organizer
  第１６回世界肺癌学会総会
- Place of Presentation
  デンバー、コロラド州、USA
- Year and Date
  2015-09-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462125
[Presentation] 非小細胞肺癌におけるFGFR2 発現の検討2011
- Author(s)
  菊地柳太郎、喜多村次郎、石川将史、小林正嗣、中山英、毛受暁史、園部誠、宮原亮、黄政龍、伊達洋至
- Organizer
  第28回日本呼吸器外科学会総会
- Place of Presentation
  大分
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-23659666
[Presentation] Overexpression of FGFR2 gene is associated with advanced stage squamous cell carcinoma of the lung2011
- Author(s)
  Kikuchi R, Huang CL, Miyahara R, Sonobe M, Menju T, Kobayashi M, Ishikawa M, Kitamura J, Date H
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlang, U.S.A.
- Year and Date
  2011-04-02
- Data Source
  KAKENHI-PROJECT-23659666
[Presentation] 悪性胸膜中皮腫においてWnt2B は腫瘍増殖に影響する2011
- Author(s)
  小林正嗣、黄政龍、喜多村次郎、菊地柳太郎、石川将史、毛受暁史、園部誠、宮原亮、伊達洋至
- Organizer
  第28回日本呼吸器外科学会総会
- Place of Presentation
  大分
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-23659666
[Presentation] The intratumoral Wnt2B expression affects tumor progression in malignant pleural mesotheliomas2011
- Author(s)
  Kobayashi M, Huang CL, Miayahara R, Sonobe M, Menju T, Kikuchi R, Ishikawa M, Kitamura J, Itoi K, Date H
- Organizer
  AACR 102nd Annual Meeting
- Place of Presentation
  Orlang, U.S.A.
- Year and Date
  2011-04-02
- Data Source
  KAKENHI-PROJECT-23659666
[Presentation] 非小細胞肺癌における EML4-ALK 融合遺伝子の臨床病理学的検討2010
- Author(s)
  小林正嗣、園部誠、石川将史、菊地柳太郎、喜多村次郎、中山英、毛受暁史、高橋剛士、大久保憲一、伊達洋至
- Organizer
  第27回日本呼吸器外科学会総会
- Place of Presentation
  仙台
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22591563

1. SONOBE Makoto (00432378)

# of Collaborated Projects: 8 results

# of Collaborated Products: 25 results
2. DATE Herushi (60252962)

# of Collaborated Projects: 5 results

# of Collaborated Products: 17 results
3. Sato Masaaki (00623109)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. Aoyama Akihiro (60379047)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. TAKAHASHI Tiyoshi (90527079)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 宮原亮 (20335285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 黄政龍 (10271511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. 大政貢 (80379049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤篤靖 (30706677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. MIYAMOTO Ei

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. TAKAHAGI Akihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KAWASHIMA Mitsuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SABE Hisataka

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. 廣田喜一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 佐邉寿孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Menjyu Toshi 毛受 暁史

MENJYU Toshi 毛受 暁史

毛受 暁史 メンジュ トシ

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The elucidation of mechanisms and the development of novel therapeutic methods for mutant p53-induced EMT in lung cancerPrincipal Investigator

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The elucidation of the novel therapy specific for lung cancer targeting Arf6-induced EMTPrincipal Investigator

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The identification of targeting molecules for EMT-activating signals from ErbB family receptor in lung cancerPrincipal Investigator

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[Journal Article] A novel cell-based assay for the high-throughput screening of epithelial?mesenchymal transition inhibitors: Identification of approved and investigational drugs that inhibit epithelial?mesenchymal transition2023

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[Journal Article] Lung fibrogenic microenvironment in mouse reconstitutes human alveolar structure and lung tumor2022

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[Journal Article] Nrf2/p?Fyn/ABCB1 axis accompanied by p?Fyn nuclear accumulation plays pivotal roles in vinorelbine resistance in non?small cell lung cancer2022

Menjyu Toshi 毛受暁史

MENJYU Toshi 毛受暁史

毛受暁史メンジュトシ