Kasai Tomonari 笠井智成

… Alternative Names

Researcher Number	30530191
Other IDs
Affiliation (Current)	2021: 岡山大学, 中性子医療研究センター, 准教授
Affiliation (based on the past Project Information) *help	2021: 岡山大学, 学内共同利用施設等, 准教授 2019: 岡山大学, 中性子医療研究センター, 特任准教授 2018: 東京工科大学, 応用生物学部, 准教授 2016 – 2017: 岡山大学, 自然科学研究科, 特別契約職員(講師) 2014 – 2016: 岡山大学, 自然科学研究科, 講師 2013: 岡山大学, 自然科学研究科, 助教 2012: 岡山大学, 自然科学研究科, 技術補佐員
Review Section/Research Field	Principal Investigator Nanomaterials/Nanobioscience / Basic Section 27040:Biofunction and bioprocess engineering-related Except Principal Investigator Tumor biology / Biomedical engineering/Biomaterial science and engineering / Basic Section 42040:Laboratory animal science-related
Keywords	Principal Investigator 三次元細胞培養 / ドラッグデリバリーシステム / 酸化鉄マイクロチューブ / ヒト癌由来細胞株 / チューブ状酸化鉄 / L-BIOX / HepG2細胞 / 細胞塊 / 多孔質構造 / シリカ … More Except Principal Investigator がん幹細胞 / iPS細胞 / 人工多能性幹細胞 / 動物モデル / 薬物送達システム / 分子標的薬 / 抗がん剤 / 根本的治療 / 細胞死 / 制がん剤 / 根本治療 / VEGFR-2 阻害剤 / キナーゼ阻害剤 / 網羅的解析 / 阻害剤 / 肝がん / 実験動物モデル / 肝がん幹細胞 / 肝胆膵がん / オルガノイド / 多能性幹細胞 Less

悪性がん根治を実現するBNCTの新規ホウ素薬剤創出とモデル作製Principal InvestigatorOngoing
- Principal Investigator
  
  笠井智成
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  Okayama University
Preparation of and drug discovery studies by hepatobiliary pancreatic cancer stem cell models derived from organoid and induced pluripotent stem cellsOngoing
- Principal Investigator
  
  岩崎良章
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Okayama University
Establishment and application of animal model of liver cancer stem cell using induced pluripotent stem cells
- Principal Investigator
  
  IWASAKI Yoshiaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
Analysis of molecular mechanisms involved in the conversion of iPSs into cancer stem cells
- Principal Investigator
  
  Seno Masaharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
Development of the strategy for fundamental therapy of cancer using iPS derived Cancer Stem cell models
- Principal Investigator
  
  Seno Masaharu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Okayama University
An analysis of bacteria, which produce 'Biotech-materials'Principal Investigator
- Principal Investigator
  
  KASAI Tomonari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Okayama University

All 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment2018
- Author(s)
  Oo AKK, Calle AS, Nair N, Mahmud H, Vaidyanath A, Yamauchi J, Khayrani AC, Du J, Alam MJ, Seno A, Mizutani A, Murakami H, Iwasaki Y, Chen L, Kasai T, Seno M
- Journal Title
  
  Transl Oncol
  
  Volume: 11 Pages: 653-663
- DOI
  10.1016/j.tranon.2018.03.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07116
[Journal Article] A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment2017
- Author(s)
  Neha Nair, Anna Sanchez Calle, Maram Hussein Zahra, Marta Prieto-Vila, Aung Ko Ko Oo, Laura Hurley, Arun Vaidyanath, Akimasa Seno, Junko Masuda, Yoshiaki Iwasaki, Hiromi Tanaka, Tomonari Kasai, Masaharu Seno
- Journal Title
  
  Scientific Reports
  
  Volume: 7
- DOI
  10.1038/s41598-017-07144-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07116
[Journal Article] Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting2017
- Author(s)
  Masuda J, Kawamoto H, Strober W, Takayama E, Mizutani A, Murakami H, Ikawa T, Kitani A, Maeno N, Shigehiro T, Satoh A, Seno A, Arun V, Kasai T, Fuss IJ, Katsura Y, Seno M
- Journal Title
  
  Appl Biochem Biotechnol.
  
  Volume: 180 Pages: 1559-1573
- DOI
  10.1007/s12010-016-2187-4
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04743, KAKENHI-PROJECT-15J08264, KAKENHI-PROJECT-26640079, KAKENHI-PROJECT-15K11096
[Journal Article] A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm).2016
- Author(s)
  Calle AS, Nair N, Oo AK, Prieto-Vila M, Koga M, Khayrani AC, Hussein M, Hurley L, Vaidyanath A, Seno A, Iwasaki Y, Calle M, Kasai T, Seno M
- Journal Title
  
  Am J Cancer Res
  
  Volume: 6 Pages: 2799-2815
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm)2016
- Author(s)
  Calle AS, Nair N, Oo AK, Prieto-Vila M, Koga M, Khayrani AC, Hussein M, Hurley L, Vaidyanath A, Seno A, Iwasaki Y, Calle M, Kasai T, Seno M
- Journal Title
  
  Am J Cancer Res
  
  Volume: 6 Pages: 2799-2815
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] iPSC-derived cancer stem cells provide a model of tumor vasculature.2016
- Author(s)
  Prieto-Vila M, Yan T, Calle AS, Nair N, Hurley L, Kasai T, Kakuta H, Masuda J, Murakami H, Mizutani A, Seno M.
- Journal Title
  
  Am J Cancer Res
  
  Volume: 6 Pages: 1906-1921
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map.2016
- Author(s)
  Seno A, Kasai T, Ikeda M, Vaidyanath A, Masuda J, Mizutani A, Murakami H, Ishikawa T, Seno M
- Journal Title
  
  Cancer Inform
  
  Volume: 15 Pages: 163-178
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] A Unique Procedure to Identify Cell Surface Markers Through a Spherical Self-Organizing Map Applied to DNA Microarray Analysis2016
- Author(s)
  Y. Sugii, T. Kasai, M. Ikeda, A. Vaidyanath, K. Kumon, A. Mizutani, A. Seno, H. Tokutaka, T. Kudoh, M. Seno
- Journal Title
  
  Biomarkers in Cancer
  
  Volume: 8 Pages: 17-23
- DOI
  10.4137/bic.s33542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26410120, KAKENHI-PROJECT-26640079
[Journal Article] iPSC-derived cancer stem cells provide a model of tumor vasculature.2016
- Author(s)
  Prieto-Vila M, Yan T, Calle AS, Nair N, Hurley L, Kasai T, Kakuta H, Masuda J, Murakami H, Mizutani A, Seno M.
- Journal Title
  
  Am J Cancer Res
  
  Volume: 6 Pages: 1906-1921
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map.2016
- Author(s)
  Seno A, Kasai T, Ikeda M, Vaidyanath A, Masuda J, Mizutani A, Murakami H, Ishikawa T, Seno M
- Journal Title
  
  Cancer Inform
  
  Volume: 15 Pages: 163-178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] Insight into Cancer Stem Cell Niche; Lessons from Cancer Stem Cell Models Generated In Vitro2015
- Author(s)
  MizutaniA, Yan T, Vaidyanath A, Masuda J, Seno A, Kasai T, Murakami H, Seno M
- Journal Title
  
  Stem Cell Biology and Regenerative Medicine (Springer International Publishing)
  
  Volume: 1 Pages: 211-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] Sperical Self-organizing Map Detects MYBL1 as Candidate Gene for Triple-Negative Breast Cancer2015
- Author(s)
  M. Ikeda, K. Kumon, K. Omoto, Y. Sugii, A. Mizutani, A. Vaidyanath, T. Kudoh, T. Kasai, S. Masuda, M. Seno
- Journal Title
  
  Neuroscience and Biomedical Engineering
  
  Volume: 3 Pages: 94-101
- DOI
  10.2174/2213385203666151026235610
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26410120, KAKENHI-PROJECT-26640079, KAKENHI-PROJECT-25242045
[Journal Article] Insight into Cancer Stem Cell Niche; Lessons from Cancer Stem Cell Models Generated In Vitro2015
- Author(s)
  MizutaniA, Yan T, Vaidyanath A, Masuda J, Seno A, Kasai T, Murakami H, Seno M
- Journal Title
  
  Stem Cell Biology and Regenerative Medicine (Springer International Publishing)
  
  Volume: 1 Pages: 211-226
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] In vitro anti-proliferative and anti-angiogenic activities of thalidomide dithiocarbamate analogs.2014
- Author(s)
  El-Aarag BY, Kasai T, Zahran MA, Zakhary NI, Shigehiro T, Sekhar SC, Agwa HS, Mizutani A, Murakami H, Kakuta H, Seno M.
- Journal Title
  
  International Immunopharmacology
  
  Volume: 2 Pages: 283-92
- DOI
  10.1016/j.intimp.2014.05.007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510151, KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26640079
[Journal Article] Mouse induced pluripotent stem cell microenvironment generates epithelial-mesenchymal transition in mouse Lewis lung cancer cells.2014
- Author(s)
  Chen L, Mizutani A, Kasai T, Yan T, Jin G, Vaidyanath A, El-Aarag BY, Liu Y, Kudoh T, Salomon DS, Fu L, Seno M.
- Journal Title
  
  American Journal of Cancer Research
  
  Volume: 1 Pages: 80-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] Efficient Drug Delivery of Paclitaxel Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes Preparation2014
- Author(s)
  Shigehiro T, Kasai T, Murakami M, Sekhar SC, Tominaga Y, Okada M, Kudoh T, Mizutani A, Murakami H, Salomon DS, Mikuni K, Mandai T, Hamada H, Seno
- Journal Title
  
  PLS One
  
  Volume: 9
- DOI
  10.1371/journal.pone.0107976
- NAID
  120005477121
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510151, KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26410120, KAKENHI-PROJECT-26640079
[Journal Article] Characterization of Cancer Stem-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Transformed by Tumor-Derived Extracellular Vesicles2014
- Author(s)
  Yan T, Mizutani A, Chen L, Takaki M, Hiramoto Y, Matsuda S, Shigehiro T, Kasai T, Kudoh T, Murakami H, Masuda J, Hendrix MJ, Strizzi L, Salomon DS, Fu L, Seno M.
- Journal Title
  
  Anticancer Research
  
  Volume: 5 Pages: 572-584
- DOI
  10.7150/jca.8865
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24501315, KAKENHI-PROJECT-24510151, KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26410120, KAKENHI-PROJECT-26640079
[Journal Article] Cancer stem cells maintain a hierarchy of differentiation by creating their niche2014
- Author(s)
  Matsuda S, Yan T, Mizutani A, Sota T, Hiramoto Y, Prieto-Vila M, Chen L, Satoh A, Kudoh T, Kasai T, Murakami H, Fu L, Salomon DS, Seno M
- Journal Title
  
  International Journal of Cancer
  
  Volume: 00 Pages: 0-0
- DOI
  10.1002/ijc.28648
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23570167, KAKENHI-PROJECT-23650598, KAKENHI-PROJECT-24501315, KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26640079
[Journal Article] Mouse induced pluripotent stem cell microenvironment generates epithelial-mesenchymal transition in mouse Lewis lung cancer cells.2014
- Author(s)
  Chen L, Mizutani A, Kasai T, Yan T, Jin G, Vaidyanath A, El-Aarag BY, Liu Y, Kudoh T, Salomon DS, Fu L, Seno M.
- Journal Title
  
  American Journal of Cancer Research
  
  Volume: 1 Pages: 80-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] Cancer stem cells converted from pluripotent stem cells and the cancerous niche.2014
- Author(s)
  Kasai T, Chen L, Mizutani A, Kudoh T, Murakami H, Fu L, Seno M
- Journal Title
  
  Journal of Stem Cells & Regenerative Medicine
  
  Volume: 1 Pages: 2-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24510151
[Journal Article] Cancer stem cells converted from pluripotent stem cells and the cancerous niche.2014
- Author(s)
  Kasai T, Chen L, Mizutani A, Kudoh T, Murakami H, Fu L, Seno M
- Journal Title
  
  Journal of Stem Cells & Regenerative Medicine
  
  Volume: 1 Pages: 2-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25242045
[Journal Article] Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells.2014
- Author(s)
  El-Ghlban S, Kasai T, Shigehiro T, Yin HX, Sekhar S, Ida M, Sanchez A, Mizutani A, Kudoh T, Murakami H, Seno M
- Journal Title
  
  Biomed Research International
  
  Volume: - Pages: 152659-152659
- DOI
  10.1155/2014/152659
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510151, KAKENHI-PROJECT-25242045, KAKENHI-PROJECT-26640079
[Journal Article] Cancer stem cells converted from pluripotent stem cells and the cancerous niche.2014
- Author(s)
  Kasai T, Chen L, Mizutani A, Kudoh T, Murakami H, Fu L, Seno M
- Journal Title
  
  Journal of Stem Cells & Regenerative Medicine
  
  Volume: 1 Pages: 2-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640079
[Journal Article] Chlorotoxin fused to IgG-Fc inhibits glioblastoma cell motility via receptor-mediated endocytosis2013
- Author(s)
  T. Kasai and M. Okada, et al.
- Journal Title
  
  J.Drug Deliv
  
  Volume: 2012
- DOI
  10.1155/2012/975763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J08532, KAKENHI-PROJECT-23650598, KAKENHI-PROJECT-24510151
[Journal Article] Identification of caveolin-1 as a potential causative factor in the generation of trastuzumab resistance in breast cancer cells.2013
- Author(s)
  Sekhar SC, Kasai T, Satoh A, Shigehiro T, Mizutani A, Murakami H, El-Aarag BY, Salomon DS, Massaguer A, de Llorens R, Seno M
- Journal Title
  
  J Cancer.
  
  Volume: 4 Pages: 391-401
- DOI
  10.7150/jca.6470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23570167, KAKENHI-PROJECT-24510151
[Patent] がんの非ヒトモデル動物及びその作製方法、がん幹細胞及びその製造方法2016
- Inventor(s)
  妹尾昌治、笠井智成、岩崎良章、大原利章、廣畑　聡、加来田博貴
- Industrial Property Rights Holder
  国立大学法人　岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-16K07116
[Presentation] ヒトiPS細胞から作製するがん幹細胞モデル2016
- Author(s)
  五味真知、星川健太、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 化学物質によるがん幹細胞誘導性メカニズムの解明2016
- Author(s)
  松本拓馬、佐々田沙紀、池田雅志、Anna Sanchez Calle、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 胚様体形成させたiPS細胞から誘導するがん幹細胞2016
- Author(s)
  古賀めぐみ, Anna Sanchez Calle, 岩崎良章, 笠井智成, 妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Exploration of Target Molecules and Related Pathways Affecting the Conversion of iPSCs into Cancer Stem Cells by Chemical Compounds2016
- Author(s)
  Takayuki Kudoh, Saki Sasada, Junko Masuda, Masashi Ikeda, Takuma Matsumoto, Anna Sanchez Calle, Neha Nair, Mami Asakura, Tomonari Kasai, Masaharu Seno
- Organizer
  第５回生命医薬情報学連合大会
- Place of Presentation
  東京
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] 胚様体形成させたiPS細胞から誘導するがん幹細胞2016
- Author(s)
  古賀めぐみ、Anna Sanchez Calle、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] Exploration of Target Molecules and Related Pathways Affecting the Conversion of iPSCs into Cancer Stem Cells by Chemical Compounds2016
- Author(s)
  Takayuki Kudoh, Saki Sasada, Junko Masuda, Masashi Ikeda, Takuma Matsumoto, Anna Sanchez Calle, Neha Nair, Mami Asakura, Tomonari Kasai, Masaharu Seno
- Organizer
  第５回生命医薬情報学連合大会
- Place of Presentation
  東京
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] iPSC derived CSC model with lung metastasis developed in the microenvironment of lung carcinoma.2016
- Author(s)
  Aung Ko Ko Oo, Tomonori Kasai, Arun Vaidyanath, H.B. Mahmud, Neha Nair, Anna S. Calle, Masaharu Seno.
- Organizer
  ASCB annual meeting 2016
- Place of Presentation
  サンフランシスコ　アメリカ
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] The significance of c-Kit proto-oncogene in iCSC-derived PDAC model2016
- Author(s)
  Anna Sanchez Calle, Kenta Hoshikawa, Neha Nair, Marta Prieto-Vila, Arun Vaidyanath, Tomonari Kasai, Masaharu Seno
- Organizer
  AACR Annual meeting 2016
- Place of Presentation
  ニューオリンズ　アメリカ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] iPSC derived CSC model with lung metastasis developed in the microenvironment of lung carcinoma.2016
- Author(s)
  Aung Ko Ko Oo, Tomonori Kasai, Arun Vaidyanath, H.B. Mahmud, Neha Nair, Anna S. Calle, Masaharu Seno.
- Organizer
  ASCB annual meeting 2016
- Place of Presentation
  サンフランシスコ　アメリカ
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 胚様体形成させたiPS細胞から誘導するがん幹細胞2016
- Author(s)
  古賀めぐみ、Anna Sanchez Calle、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07116
[Presentation] ヒトiPS細胞から作製するがん幹細胞モデル2016
- Author(s)
  五味真知、星川健太、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07116
[Presentation] The significance of c-Kit proto-oncogene in iCSC-derived PDAC model2016
- Author(s)
  Anna Sanchez Calle, Kenta Hoshikawa, Neha Nair, Marta Prieto-Vila, Arun Vaidyanath, Tomonari Kasai, Masaharu Seno
- Organizer
  AACR Annual meeting 2016
- Place of Presentation
  ニューオリンズ　アメリカ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Cancer stem cells as the novel origin of cancer-associated fibroblast-like cells2016
- Author(s)
  Neha Nair, Arun Vaidyanath, Kenta Hoshikawa, Anna Sanchez Calle, Tomonari Kasai, Masaharu Seno
- Organizer
  AACR Annual meeting 2016
- Place of Presentation
  ニューオリンズ　アメリカ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] TALE-転写因子技術を利用したTcf3遺伝子発現の抑制2016
- Author(s)
  増田潤子、河本宏、高山英次、水谷昭文、村上宏、伊川友活、前野成実、重廣司、佐藤あやの、妹尾彬正、Arun Vaidyanath、笠井智成、桂義元、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] ヒトiPS細胞から作製するがん幹細胞モデル2016
- Author(s)
  五味真知、星川健太、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] 化学物質によるがん幹細胞誘導性メカニズムの解明2016
- Author(s)
  松本拓馬, 佐々田沙紀, 池田雅志, Anna Sanchez Calle, 笠井智成, 妹尾昌治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Cancer stem cells as the novel origin of cancer-associated fibroblast-like cells2016
- Author(s)
  Neha Nair, Arun Vaidyanath, Kenta Hoshikawa, Anna Sanchez Calle, Tomonari Kasai, Masaharu Seno
- Organizer
  AACR Annual meeting 2016
- Place of Presentation
  ニューオリンズ　アメリカ
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Daunorubicin induced caspase-independent apoptosis in a cancer stem model cell.2016
- Author(s)
  Akifumi Mizutani, Kazuki Aizawa, Ryoma Onoue, Junko Masuda, Akimasa Seno, Arun Vaidyanath, Tomonari Kasai, Hiroshi Murakami, Masaharu Seno
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Exploration of Target Molecules Affecting the Conversion of iPS Cells into Cancer Stem Cells Using Chemical Compound Library2015
- Author(s)
  Takayuki Kudoh, Tomonari Kasai, Saki Sasada, Kenta Hoshikawa, Takuma Matsumoto, Anna Sanchez Calle, Arun Vaidyanath, Masaharu Seno
- Organizer
  CBI学会2015年大会
- Place of Presentation
  東京
- Year and Date
  2015-10-27
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 多能性幹細胞から作るがん幹細胞モデル2015
- Author(s)
  笠井智成、バイディナードアルン、竹尻崇人、村上知加恵、ナイルネハ、サンチェス　カレ　アンナ、妹尾彬正、水谷昭文、工藤孝幸、陳凌、妹尾昌治
- Organizer
  第74 回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] がん幹細胞ニッチでのがん幹細胞自己複製促進2015
- Author(s)
  恩賀咲、平本祐樹、松田修一、村上宏、増田潤子、Arun Vaidyanath、笠井智成、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Acquisition of immortalization prior to malignancy during the miPS-CSC generation2015
- Author(s)
  Prieto Vila M, Shigehiro T, Sanchez Calle A, Kasai T, Murakami H, Mizutani A, Seno M
- Organizer
  第74 回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Acquisition of immortalization prior to malignancy during the miPS-CSC generation2015
- Author(s)
  Prieto Vila M, Shigehiro T, Sanchez Calle A, Kasai T, Murakami H, Mizutani A, Seno M
- Organizer
  第74 回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] がん幹細胞miPS-LLCcmが形成する微小環境によるNanogタンパク質の局在変化2015
- Author(s)
  公文一輝、本山大暉、増田潤子、Marta Prieto Vila、相澤一輝、尾上稜馬、笠井智成、村上宏、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] 多能性幹細胞から作るがん幹細胞モデル2015
- Author(s)
  笠井智成、バイディナードアルン、竹尻崇人、村上知加恵、ナイルネハ、サンチェス　カレ　アンナ、妹尾彬正、水谷昭文、工藤孝幸、陳凌、妹尾昌治
- Organizer
  第74 回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] シグナル伝達阻害剤によるがん幹細胞誘導メカニズムの解析2015
- Author(s)
  佐々田沙紀、星川健太、松本拓馬、Anna Sanchez Calle、水谷昭文、Arun Vaidyanath、増田潤子、笠井智成、妹尾昌治
- Organizer
  第38 回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] がん幹細胞ニッチでのがん幹細胞自己複製促進2015
- Author(s)
  恩賀咲、平本祐樹、松田修一、村上宏、増田潤子、Arun Vaidyanath、笠井智成、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 乳癌と正常組織を識別する遺伝子セットの網羅的探索2015
- Author(s)
  池田雅志、Arun Vaidyanath、公文一輝、水谷昭文、妹尾彬正、工藤孝幸、笠井智成、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 肝臓がんへ分化するがん幹細胞モデルの作成2015
- Author(s)
  堤愛姫、竹尻崇人、水谷昭文、Arun Vaidyanath、大原利章、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第38 回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Exploration of Target Molecules Affecting the Conversion of iPS Cells into Cancer Stem Cells Using Chemical Compound Library2015
- Author(s)
  Takayuki Kudoh, Tomonari Kasai, Saki Sasada, Kenta Hoshikawa, Takuma Matsumoto, Anna Sanchez Calle, Arun Vaidyanath, Masaharu Seno
- Organizer
  CBI学会2015年大会
- Place of Presentation
  東京
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] マウスiPS細胞由来がん幹細胞におけるダウノルビシンによるp53経路の活性化2015
- Author(s)
  相澤一輝、宗田龍幸、谷口早紀、尾上稜馬、村上宏、増田潤子、Arun Vaidyanath、笠井智成、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] 化学物質のがん幹細胞誘導性に関するin vitroにおける簡易評価技術の開発2015
- Author(s)
  佐々田沙紀、星川健太、松本拓馬、Anna Sanchez Calle、Arun Vaidyanath、増田潤子、笠井智成、妹尾昌治
- Organizer
  日本動物実験代替法学会　第28回大会
- Place of Presentation
  横浜
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] 化学物質のがん幹細胞誘導性に関するin vitroにおける簡易評価技術の開発2015
- Author(s)
  佐々田沙紀、星川健太、松本拓馬、Anna Sanchez Calle、Arun Vaidyanath、増田潤子、笠井智成、妹尾昌治
- Organizer
  日本動物実験代替法学会　第28回大会
- Place of Presentation
  横浜
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] がん幹細胞miPS-LLCcmが形成する微小環境によるNanogタンパク質の局在変化2015
- Author(s)
  公文一輝、本山大暉、増田潤子、Marta Prieto Vila、相澤一輝、尾上稜馬、笠井智成、村上宏、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] マウスiPS細胞由来がん幹細胞におけるダウノルビシンによるp53経路の活性化2015
- Author(s)
  相澤一輝、宗田龍幸、谷口早紀、尾上稜馬、村上宏、増田潤子、Arun Vaidyanath、笠井智成、水谷昭文、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 肝臓がんへ分化するがん幹細胞モデルの作成2015
- Author(s)
  堤愛姫、竹尻崇人、水谷昭文、Arun Vaidyanath、大原利章、岩崎良章、笠井智成、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] 乳癌と正常組織を識別する遺伝子セットの網羅的探索2015
- Author(s)
  池田雅志、Arun Vaidyanath、公文一輝、水谷昭文、妹尾彬正、工藤孝幸、笠井智成、妹尾昌治
- Organizer
  第38 回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] シグナル伝達阻害剤によるがん幹細胞誘導メカニズムの解析2015
- Author(s)
  佐々田沙紀、星川健太、松本拓馬、Anna Sanchez Calle、水谷昭文、Arun Vaidyanath、増田潤子、笠井智成、妹尾昌治
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] iPS 細胞から作るがん幹細胞ライブラリー-抗がん剤スクリーニングプラットフォームとして-2014
- Author(s)
  笠井智成、本庶仁子、公文一輝、星川健太、竹尻崇人、朝倉真実、水谷昭文、村上宏、妹尾昌治
- Organizer
  化学療法基盤支援活動第3 回シンポジウム
- Place of Presentation
  沖縄
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] iPS 細胞から作るがん幹細胞ライブラリー-抗がん剤スクリーニングプラットフォームとして-2014
- Author(s)
  笠井智成、本庶仁子、公文一輝、星川健太、竹尻崇人、朝倉真実、水谷昭文、村上宏、妹尾昌治
- Organizer
  化学療法基盤支援活動第3 回シンポジウム
- Place of Presentation
  沖縄
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Anti-cancer activity of immunoliposomes encapsulated effective amount of glycosylated paclitaxel with novel loading strategy2014
- Author(s)
  Tsukasa Shigehiro, Tomonari Kasai, Akifumi Mizutani, Hiroshi Murakami, Katsuhiko Mikuni, Tadakatsu Mandai, Hiroki Hamada, Masaharu Seno
- Organizer
  American Association for Cancer Research Annual Meeting 2014
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] iPS 細胞から作るがん幹細胞ライブラリー-抗がん剤スクリーニングプラットフォームとして-2014
- Author(s)
  笠井智成、本庶仁子、公文一輝、星川健太、竹尻崇人、朝倉真実、水谷昭文、村上宏、妹尾昌治
- Organizer
  化学療法基盤支援活動第3 回シンポジウム
- Place of Presentation
  沖縄
- Year and Date
  2014-05-12
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] In vitro niche created by cancer stem-like cells derived from mouse induced pluripotent stem cell2013
- Author(s)
  A. Mizutani, S. Matsuda, T. Yan, T. Sota, T. Kasai, T. Kudoh, H. Murakami, M. Seno.
- Organizer
  American association for cancer research AACR annual meeting 2013
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] A novel remote loading method with solubility gradient to encapsulate effevtive amount of taxanes into liposomes.2013
- Author(s)
  T. Shigehiro, T. Kasai, A. Mizutani, H. Murakami, K. Mikuni, T. Mandai, H. Hamada, M. Seno.
- Organizer
  American association for cancer research AACR annual meeting 2013
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] ヒアルロン酸を用いたCD44高発現細胞の濃縮2013
- Author(s)
  位田弥希子、笠井智成、村上宏、水谷昭文、妹尾昌治
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] 高効率に糖修飾パクリタキセルを封入したイムノリポソームによる抗がん活性評価2013
- Author(s)
  重廣司、笠井智成、富永有貴、水谷昭文、村上宏、三國克彦、萬代忠勝、濱田博喜、妹尾昌治
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] Chlorotoxin-Fc fusion inhibits release of MMP-2 from pancreatic cancer cells (PANC-1)2013
- Author(s)
  EL-Ghlban S., Kasai T., Kanao S., Mizutani A., Murakami H., Seno M.
- Organizer
  第３６回　日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] Development of the system to target CD44 protein for treatment of glioma2012
- Author(s)
  M.Ida, T.Kasai, Y.Sugii, T.Kudoh, A.Mizutani, H.Murakami, M.Seno
- Organizer
  日本分子生物学会　第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] Preparation and evaluation of HER2 targeting immunoliposomes with paclitaxel glycoside2012
- Author(s)
  T.Shigehiro, T.Kasai, T.Matsumoto, M.Okada, A.Mizutani, T.Kudoh, H.Murakami, K.Mikuni, T.Mandai, H.Hamada, M.Seno
- Organizer
  日本分子生物学会　第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] パクリタキセルグリコシド内封リポソームによるHER2過剰発現がん細胞の標的2012
- Author(s)
  重廣司、笠井智成、岡田将史、水谷昭文、工藤孝幸、三國克彦、萬代忠勝、妹尾昌治
- Organizer
  日本癌学会　第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] A new three dimensional culturing system to obtain scarce proteins and peptides2012
- Author(s)
  Y.Tomoda, T.Kasai, Y.Miyawaki, H.Hashimoto, T.Suzuki, T.Kudoh, J.Takada, M.Seno
- Organizer
  日本分子生物学会　第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] Influence of caveolin-1 in ligand based targeting of ErbB2 in breast cancer cell line SKBR32012
- Author(s)
  S.Sekhar, T.Kasai, T.Hashizume, T.Kudoh, A.Mizutani, A.Satoh, H.Murakami, M.Seno
- Organizer
  日本分子生物学会　第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived exosomes/microvesicles
- Author(s)
  Yan T, Masuda J, Mizutani A, Chen L, Shigehiro T, Matsuda S, Kasai T, Kudoh T, Murakami H, Hendrix MJ, Strizzi L, Salomon DS, Seno M
- Organizer
  AACR Annual meeting 2014
- Place of Presentation
  サンディエゴ　アメリカ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] がん幹細胞ニッチにおけるがん幹細胞の自己複製制御機構の解析
- Author(s)
  平本祐樹、渡邉直哉、松田修一、Yan T、Marta P Vila、水谷昭文、村上宏、笠井智成、妹尾昌治
- Organizer
  第37 回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] Cancer stem cells maintain a hierarchy of differentiation by creating their niche
- Author(s)
  Mizutani A, Matsuda S, Yan T, Prieto-Vila M, Chen L, Satoh A, Kasai T, Masuda J, Kudoh T, Murakami H, Fu L, Salomon DS, Seno M
- Organizer
  AACR Annual meeting 2014
- Place of Presentation
  サンディエゴ　アメリカ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] ヒトiPS 細胞から作るがん幹細胞
- Author(s)
  笠井智成、水谷昭文、工藤孝幸、佐藤あやの、陳凌、妹尾昌治
- Organizer
  第37 回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] Cancer stem cells maintain a hierarchy of differentiation by creating their niche
- Author(s)
  Mizutani A, Matsuda S, Yan T, Prieto-Vila M, Chen L, Satoh A, Kasai T, Masuda J, Kudoh T, Murakami H, Fu L, Salomon DS, Seno M
- Organizer
  AACR Annual meeting 2014
- Place of Presentation
  サンディエゴ　アメリカ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] ヒトiPS 細胞から作るがん幹細胞
- Author(s)
  笠井智成、水谷昭文、工藤孝幸、佐藤あやの、陳凌、妹尾昌治
- Organizer
  第37 回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26640079
[Presentation] Characterization of cancer stem-like cells derived from mouse induced pluripotent stem cells transformed by tumor-derived exosomes/microvesicles
- Author(s)
  Yan T, Masuda J, Mizutani A, Chen L, Shigehiro T, Matsuda S, Kasai T, Kudoh T, Murakami H, Hendrix MJ, Strizzi L, Salomon DS, Seno M
- Organizer
  AACR Annual meeting 2014
- Place of Presentation
  サンディエゴ　アメリカ
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-25242045
[Presentation] ヒトiPS 細胞から作るがん幹細胞
- Author(s)
  笠井智成、水谷昭文、工藤孝幸、佐藤あやの、陳凌、妹尾昌治
- Organizer
  第37 回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24510151
[Presentation] がん幹細胞ニッチにおけるがん幹細胞の自己複製制御機構の解析
- Author(s)
  平本祐樹、渡邉直哉、松田修一、Yan T、Marta P Vila、水谷昭文、村上宏、笠井智成、妹尾昌治
- Organizer
  第37 回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25242045

1. SENO Masaharu (90243493)

# of Collaborated Projects: 3 results

# of Collaborated Products: 82 results
2. IWASAKI Yoshiaki (00314667)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. 工藤孝幸 (00346412)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
4. 水谷昭文 (50598331)

# of Collaborated Projects: 2 results

# of Collaborated Products: 47 results
5. 村上宏 (90260174)

# of Collaborated Projects: 2 results

# of Collaborated Products: 34 results
6. HASHIMOTO Hideki (60579556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 日沼州司 (60550522)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 加来田博貴 (80362961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 浜田博喜 (10164914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 増田潤子 (20424674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
11. TAKAYAMA Eiji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 佐藤あやの

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 河本宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kasai Tomonari 笠井 智成

笠井 智成 カサイ トモナリ

KASAI Tomonari 笠井 智成

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悪性がん根治を実現するBNCTの新規ホウ素薬剤創出とモデル作製Principal InvestigatorOngoing

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Preparation of and drug discovery studies by hepatobiliary pancreatic cancer stem cell models derived from organoid and induced pluripotent stem cellsOngoing

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Establishment and application of animal model of liver cancer stem cell using induced pluripotent stem cells

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Analysis of molecular mechanisms involved in the conversion of iPSs into cancer stem cells

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Development of the strategy for fundamental therapy of cancer using iPS derived Cancer Stem cell models

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An analysis of bacteria, which produce 'Biotech-materials'Principal Investigator

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[Journal Article] Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment2018

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[Journal Article] A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment2017

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[Journal Article] Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting2017

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[Journal Article] A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm).2016

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[Journal Article] A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm)2016

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[Journal Article] iPSC-derived cancer stem cells provide a model of tumor vasculature.2016

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[Journal Article] Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map.2016

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[Journal Article] A Unique Procedure to Identify Cell Surface Markers Through a Spherical Self-Organizing Map Applied to DNA Microarray Analysis2016

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[Journal Article] iPSC-derived cancer stem cells provide a model of tumor vasculature.2016

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Kasai Tomonari 笠井智成

笠井智成カサイトモナリ

KASAI Tomonari 笠井智成