Yamanaka Hitoki 山中仁木

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YAMANAKA Hitoki 山中仁木

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Researcher Number	30533921
Other IDs
External Links
Affiliation (Current)	2022: 信州大学, 学術研究院総合人間科学系, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2021: 信州大学, 学術研究院総合人間科学系, 准教授 2013 – 2016: 長崎大学, 先導生命科学研究支援センター, 助教 2010: 長崎大学, 医歯薬学総合研究科, 助教 2010: Nagasaki University, 大学院・医歯薬学総合研究科, 助教 2009: Nagasaki University, 先導生命科学研究支援センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Applied veterinary science / Veterinary medical science Except Principal Investigator Functional basic dentistry / Oral Science and related fields / Eating habits
Keywords	Principal Investigator ヘリコバクター属菌 / 大腸粘膜 / マウス / 腸内細菌叢 / ゲノム解析 / 人獣共通感染症 / プリオン / リコンビナントプリオン蛋白 / ワクチン / 免疫学的治療法 … More / 盲腸粘膜 / 粘膜固有層リンパ球 / ヘルパーT細胞反応 / 感染防御機構 / 生殖器 / ATP分泌性腸球菌 / Helicobacter属菌 / MIT 01-6451菌 / 垂直感染 / 病原性 / 腸管粘膜 / リンパ球 / MIT01-6451菌 / 性状 / 盲結腸粘膜 / 粘膜バリア / 抗菌ペプチド / 盲大腸粘膜 / ゲノム配列 / 炎症 / 腸粘膜IgA / 腸粘膜恒常性 … More Except Principal Investigator カルシウム / ATP / リン / 小腸 / ビタミンD / 石灰化 / カルシウム輸送 / 骨 / 恒常性 / ピロリン酸 / 細胞外小胞 / エクソソーム / 吸収 / 栄養 / 消化管 / 腸 / 腸上皮 / カルシウム吸収 / ビタミンＤ Less

Role of mucosal IgA induced by the enterohepatic Helicobacter species infection in intestinal homeostasisPrincipal Investigator
- Principal Investigator
  
  山中仁木
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Shinshu University
Mechanisms of ulcerative colitis focusing on mucosal barrier disorder caused by bacteria possessed flagellaPrincipal Investigator
- Principal Investigator
  
  Yamanaka Hitoki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Shinshu University
ATP dependent exosomes calcification and organ tropism
- Principal Investigator
  
  MASUYAMA Ritsuko
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Oral Science and related fields
- Research Institution
  Nagasaki University
study of the intestinal sensing of food elements - autonomy absorption mechanism to produce robust characteristics of the calcium metabolism
- Principal Investigator
  
  Ritsuko MASUYAMA
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Ritsumeikan University
  Nagasaki University
The roles of vitamin D dependent novel phosphate sensing-system on calcium metabolism and local calcification.
- Principal Investigator
  
  MASUYAMA Ritsuko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nagasaki University
Pathogenicity of Helicobacter species and role for development of inflammatory bowel disesasesPrincipal Investigator
- Principal Investigator
  
  YAMANAKA Hitoki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Nagasaki University
Basic study for development of prion vaccines and immunotherapeutic methods using the newly immunogensPrincipal Investigator
- Principal Investigator
  
  YAMANAKA Hitoki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  Nagasaki University

All 2020 2019 2018 2016 2015 2014 2013 2011 2010 Other

All Journal Article Presentation Book

[Book] 糖尿病・内分泌代謝科「ビタミンDの内分泌学」（担当：「ビタミンDの組織特異的作用」）2020
- Author(s)
  増山律子、山中仁木
- Publisher
  科学評論社
- ISBN
- Data Source
  KAKENHI-PROJECT-18K06019
[Book] 実験動物感染症と感染症動物モデルの現状(担当：ヘリコバクター属菌感染について)2016
- Author(s)
  山中仁木、大沢一貴
- Total Pages
  137
- Publisher
  公益社団法人日本実験動物学会
- Data Source
  KAKENHI-PROJECT-25450444
[Journal Article] Backcrossing to an appropriate genetic background improves the birth rate of carbohydrate sulfotransferase 14 gene-deleted mice2020
- Author(s)
  SHIMADA Shin、YOSHIZAWA Takahiro、TAKAHASHI Yuki、NITAHARA-KASAHARA Yuko、OKADA Takashi、NOMURA Yoshihiro、YAMANAKA Hitoki、KOSHO Tomoki、MATSUMOTO Kiyoshi
- Journal Title
  
  Experimental Animals
  
  Volume: 69 Issue: 4 Pages: 407-413
- DOI
  10.1538/expanim.19-0150
- NAID
  130007938664
- ISSN
  0007-5124, 1341-1357, 1881-7122
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08745, KAKENHI-PROJECT-19H03616, KAKENHI-PROJECT-18K06019
[Journal Article] 実験動物マウスおよびラットにおける薬剤耐性菌2020
- Author(s)
  山中仁木
- Journal Title
  
  実験動物ニュース
  
  Volume: 69 Pages: 130-133
- Data Source
  KAKENHI-PROJECT-18K06019
[Journal Article] ビタミンDの組織特異的作用2020
- Author(s)
  山中仁木、増山律子
- Journal Title
  
  糖尿病・内分泌代謝科
  
  Volume: 1 Pages: 12-17
- Data Source
  KAKENHI-PROJECT-17H01967
[Journal Article] 実験動物におけるピロリ菌以外のヘリコバクター属菌2019
- Author(s)
  山中仁木
- Journal Title
  
  信州医学雑誌
  
  Volume: 67 Pages: 81-89
- NAID
  130007655258
- Data Source
  KAKENHI-PROJECT-18K06019
[Journal Article] Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice2019
- Author(s)
  Yamanaka H, Kadomatsu R, Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Ohsawa K
- Journal Title
  
  Journal of Veterinary Science
  
  Volume: 20
- DOI
  10.4142/jvs.2019.20.e13
- NAID
  120006987736
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06019
[Journal Article] Phosphate-dependent luminal ATP metabolism regulates transcellular calcium transport in intestinal epithelial cells2018
- Author(s)
  Uekawa Atsushi、Yamanaka Hitoki、Lieben Liesbet、Kimira Yoshifumi、Uehara Mariko、Yamamoto Yoko、Kato Shigeaki、Ito Kosei、Carmeliet Geert、Masuyama Ritsuko
- Journal Title
  
  The FASEB Journal
  
  Volume: 32 Pages: 1903-1915
- DOI
  10.1096/fj.201700631r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16286, KAKENHI-PROJECT-18K06019, KAKENHI-PROJECT-17H01967, KAKENHI-PROJECT-17K19771
[Journal Article] Helicobacter sp. MIT 01-6451 infection during fetal and neonatal life in laboratory mice2015
- Author(s)
 Yamanaka H, Nakanishi T, Takagi T, Ohsawa M, Kubo N, Yamamoto N, Takemoto T, Ohsawa K
- Journal Title
 
 Experimental Animals
 
 Volume: 64 Issue: 4 Pages: 375-382
- DOI
 10.1538/expanim.15-0034
- NAID
 130005104846
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-25450444
[Journal Article] Identification and Characterization ofVancomycin-resistant Enterococcus species Frequently Isolated from Laboratory Mice2014
- Author(s)
 Yamanaka H, Takagi T, Ohsawa M, Yamamoto N, Kubo N, Takemoto T, Sasano S, Masuyama R, Ohsawa K
- Journal Title
 
 Experimental Animals
 
 Volume: 63 Issue: 3 Pages: 297-304
- DOI
 10.1538/expanim.63.297
- NAID
 130004677820
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-25450444, KAKENHI-PROJECT-26462816
[Journal Article] Pressure-assisted dissociation and degradation of “proteinase K-resistant” fibrils prepared by seeding with scrapie-infected hamster prion protein2014
- Author(s)
  Akasaka K, Maeno A, Murayama T, Tachibana H, Fujita Y, Yamanaka H, Nishida N, Atarashi R.
- Journal Title
  
  Prion
  
  Volume: 8(4) Pages: 314-318
- DOI
  10.4161/pri.32081
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23300127, KAKENHI-PROJECT-24570180, KAKENHI-PROJECT-25450444, KAKENHI-PROJECT-25640029
[Journal Article] Prevalence of an Unidentified Helicobacter Species in Laboratory Mice and its Distribution in the Hepatobiliary System and Gastrointestinal Tract2013
- Author(s)
 Yamanaka H, Arita M, Oi R, Ohsawa M, Mizushima M, Takagi T, Kubo N, Yamamoto N, Takemoto T, Ohsawa K
- Journal Title
 
 Experimental Animals
 
 Volume: 62 Issue: 2 Pages: 109-116
- DOI
 10.1538/expanim.62.109
- NAID
 10031163550
- ISSN
 0007-5124, 1341-1357, 1881-7122
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-25450444
[Journal Article] Ultrasensitive human prion detection in cerebrospinal fluid by real-time quaking-induced conversion.2011
- Author(s)
  Atarashi R, Satoh K, Sano K, Fuse T, Yamaguchi N, Ishibashi D, Matsubara T, Nakagaki T, Yamanaka H, Shirabe S, Yamada M, Mizusawa H, Kitamoto T, Klug G, McGlade A, Collins SJ, Nishida N.
- Journal Title
  
  Nat Med 17(2)
  
  Pages: 175-178
- NAID
  120006984771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21780277
[Journal Article] ペストDNAワクチン開発の検討2010
- Author(s)
  山中仁木
- Journal Title
  
  九州実験動物雑誌
  
  Volume: 26 Pages: 1-17
- Data Source
  KAKENHI-PROJECT-21780277
[Journal Article] A parenteral DNA vaccine protects against pneumonic plague.2010
- Author(s)
  Yamanaka, H., et al.
- Journal Title
  
  Vaccine
  
  Volume: 28(18) Pages: 3219-3230
- NAID
  120006984257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21780277
[Journal Article] A parenteral DNA vaccine protects against pneumonic plague.2010
- Author(s)
  Yamanaka H, Hoyt T, Yang X, Bowen R, Golden S, Crist K, Becker T, Maddaloni M, Pascual DW.
- Journal Title
  
  Vaccine 28(18)
  
  Pages: 3219-3230
- NAID
  120006984257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21780277
[Journal Article] ペストDNAワクチン開発の検討2010
- Author(s)
  山中仁木
- Journal Title
  
  九州実験動物雑誌 26
  
  Pages: 1-17
- Data Source
  KAKENHI-PROJECT-21780277
[Presentation] 筋拘縮型エーラスダンロス症候群の疾患モデル動物としてのChst14 遺伝子欠損マウスの解析2020
- Author(s)
  吉沢隆浩、嶋田新、高橋有希、水本秀二、山田修平、山中仁木、古庄知己、松本清司
- Organizer
  第67回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] Helicobacter japonicus infection contributes the development of potent mucosal barrier systems2019
- Author(s)
  山中仁木、増山律子、大沢一貴
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] ピロリ菌以外のヘリコバクター属菌ーこれまでの知見ー2019
- Author(s)
  山中仁木
- Organizer
  第8回実験動物科学シンポジウム「動物モデルを用いた感染症研究」（主催　日本実験動物学会）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] ヘリコバクター属菌感染による生体への影響とは2018
- Author(s)
  山中仁木
- Organizer
  日本実験動物医学会シンポジウム（第65回日本実験動物学会総会）
- Invited
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] 細胞外液リン量に応答するATP依存性カルシウム吸収機構の検討2018
- Author(s)
  山中仁木, 増山律子
- Organizer
  第36回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] ビタミンD応答性ATP代謝による腸上皮粘膜免疫制御2018
- Author(s)
  山中仁木, 増山律子
- Organizer
  第4回Neo Vitamin D Workshop学術集会
- Data Source
  KAKENHI-PROJECT-18K06019
[Presentation] Luminal phosphate regulates transcellular calcium transport in the intestinal epithelial cells.2016
- Author(s)
  Ritsuko Masuyama, Hitoki Yamanaka, Liesbet Lieben, Geert Carmeliet, Kosei Ito
- Organizer
  IBMS 2nd Herbert Fleisch workshop
- Place of Presentation
  Brugge (Belgium)
- Year and Date
  2016-02-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462816
[Presentation] Infection with Helicobacter species and its pathogenicity in laboratory mice2016
- Author(s)
  山中仁木
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター(大阪府大阪市)
- Year and Date
  2016-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] Helicobacter sp. MIT 01-6451 のマウスにおける垂直感染について2015
- Author(s)
  山中仁木、中西太、髙木利一、大沢牧子、久保憲昭、山本直土、嶽本剛平、大沢一貴
- Organizer
  第62回日本実験動物学会総会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] 小腸上皮ATP分解系によるカルシウム吸収調節機序の検討2014
- Author(s)
  増山律子, 上川篤志, 小原悠, 山中仁木, 伊藤公成
- Organizer
  第68回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学（札幌市）
- Year and Date
  2014-05-30
- Data Source
  KAKENHI-PROJECT-26462816
[Presentation] Isolation and characterization of Helicobacter sp. MIT 01-6451 frequently detected in SPF mice2014
- Author(s)
  Hitoki Yamanaka
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  タワーホール船堀(東京都江戸川区)
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] 国内飼養マウスで高頻度に検出される Helicobacter sp. MIT 01-6451の分離培養と性状解析2013
- Author(s)
  山中仁木, 末松貴史, 大沢牧子, 水島めぐみ, 髙木利一, 久保憲昭, 山本直土, 嶽本剛平, 大沢一貴
- Organizer
  第60回日本実験動物学会総会
- Place of Presentation
  つくば国際会議場(茨城県つくば市)
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] Helicobacter sp. MIT01-6451の分離培養と消化器系以外の組織からの検出について2013
- Author(s)
  山中仁木, 大井隆之介, 末松貴史, 大沢牧子, 髙木利一, 久保憲昭, 山本直土, 嶽本剛平, 大沢一貴
- Organizer
  第31回九州実験動物研究会総会
- Place of Presentation
  熊本県山鹿市　八千代座
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] 実験用マウスから検出されたバンコマイシン耐性腸球菌の病原関連因子の検索2013
- Author(s)
  山中仁木, 髙木利一, 大沢牧子, 山本直土, 佐々野笑行, 久保憲昭, 嶽本剛平, 大沢一貴
- Organizer
  第156回日本獣医学会学術集会
- Place of Presentation
  国立大学法人　岐阜大学(岐阜県岐阜市)
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] Distribution of unidentified Helicobacter spp.in the gastrointestinal tract and the hepatobiliary system of laboratory mice.2010
- Author(s)
  Yamanaka, H., et al.
- Organizer
  The 4th AFLAS Congress Meeting
- Place of Presentation
  台北国際コンベンションセンター(台湾・台北)
- Data Source
  KAKENHI-PROJECT-21780277
[Presentation] Distribution of unidentified Helicobacter spp.in the gastrointestinal tract and the hepatobiliary system of laboratory mice.2010
- Author(s)
  Yamanaka H, Arita M, Ohsawa M, Mizushima M, Kubo N, Takagi T, Yamamoto N, Ohsawa K.
- Organizer
  The 4th AFLAS Congress Meeting
- Place of Presentation
  台北(台湾)
- Data Source
  KAKENHI-PROJECT-21780277
[Presentation] 実験用マウスから分離されたバンコマイシン耐性腸球菌の薬剤感受性と保有する耐性関連遺伝子の検索
- Author(s)
  山中仁木、門松立樹、髙木利一、嶽本剛平、大沢牧子、松田ちあき、山本直土、久保憲昭、大沢一貴
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  国立大学法人　北海道大学(札幌市)
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] ネズミ盲腸蟯虫のイベルメクチン噴霧による駆虫方法の再検討
- Author(s)
  久保憲昭、山本直土、金子末廣、坂本雅志、山中仁木、大沢一貴
- Organizer
  第32回九州実験動物研究会総会
- Place of Presentation
  宮崎観光ホテル(宮崎市)
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] 長崎大学動物実験施設における新規導入機器と使用経験の紹介
- Author(s)
  山本直土、久保憲昭、金子末廣、坂本雅志、山中仁木、大沢一貴
- Organizer
  第32回九州実験動物研究会総会
- Place of Presentation
  宮崎観光ホテル(宮崎市)
- Year and Date
  2014-10-25 – 2014-10-26
- Data Source
  KAKENHI-PROJECT-25450444
[Presentation] Helicobacter sp. MIT 01-6451 infection during fetal and neonatal life of laboratory mice
- Author(s)
  Hitoki Yamanaka
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場(岐阜市)
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25450444

1. MASUYAMA Ritsuko (60297596)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
2. OHSAWA Kazutaka (90244756)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. 小守壽文 (00252677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 池郁生 (40183157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KASAHARA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. ATARASHI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 古庄知己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 吉沢隆浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 松本健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡田尚已

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 高橋淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 野村義宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 西田教行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 赤坂一之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamanaka Hitoki 山中 仁木

YAMANAKA Hitoki 山中 仁木

Research Projects

Research Products

Co-Researchers

Role of mucosal IgA induced by the enterohepatic Helicobacter species infection in intestinal homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of ulcerative colitis focusing on mucosal barrier disorder caused by bacteria possessed flagellaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ATP dependent exosomes calcification and organ tropism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

study of the intestinal sensing of food elements - autonomy absorption mechanism to produce robust characteristics of the calcium metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of vitamin D dependent novel phosphate sensing-system on calcium metabolism and local calcification.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pathogenicity of Helicobacter species and role for development of inflammatory bowel disesasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study for development of prion vaccines and immunotherapeutic methods using the newly immunogensPrincipal Investigator

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[Book] 糖尿病・内分泌代謝科「ビタミンDの内分泌学」（担当：「ビタミンDの組織特異的作用」）2020

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[Book] 実験動物感染症と感染症動物モデルの現状(担当：ヘリコバクター属菌感染について)2016

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[Journal Article] Backcrossing to an appropriate genetic background improves the birth rate of carbohydrate sulfotransferase 14 gene-deleted mice2020

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[Journal Article] 実験動物マウスおよびラットにおける薬剤耐性菌2020

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[Journal Article] ビタミンDの組織特異的作用2020

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[Journal Article] 実験動物におけるピロリ菌以外のヘリコバクター属菌2019

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[Journal Article] Antimicrobial resistance profiles of vancomycin-resistant Enterococcus species isolated from laboratory mice2019

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Yamanaka Hitoki 山中仁木

YAMANAKA Hitoki 山中仁木