yamano koji 山野晃史

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YAMANO Koji 山野晃史

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Researcher Number	30547526
Other IDs
Affiliation (Current)	2022: 東京医科歯科大学, 難治疾患研究所, 准教授 2022: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 研究員
Affiliation (based on the past Project Information) *help	2022: 東京医科歯科大学, 難治疾患研究所, 准教授 2017 – 2021: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主席研究員 2020: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2016: 公益財団法人東京都医学総合研究所, 生体分子先端研究分野, 主任研究員
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 44010:Cell biology-related / Basic Section 43030:Functional biochemistry-related Except Principal Investigator Complex systems
Keywords	Principal Investigator ユビキチン / ミトコンドリア / マイトファジー / オートファジー / RBR型リガーゼ / ユビキチンリガーゼ / タンパク質分解 / 細胞生物学 / Parkin / PINK1 / RBR型E3 / RBRリガーゼ … More Except Principal Investigator … More プロテアソーム / オートファジー / ユビキチン / タンパク質分解 / オルガネラ分解 / ケモテクノロジー / ケミカルバイオロジー / 細胞内分解 / PROTAC / キメラ化合物 / ステープルペプチド / 化合物スクリーニング Less

オートファジーアダプターをハブとした損傷ミトコンドリア分解機構Principal Investigator
- Principal Investigator
  
  山野晃史
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Medical and Dental University
Reconstitution of Parkin activation and recruitment to target membranePrincipal Investigator
- Principal Investigator
  
  YAMANO Koji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
ケモテクノロジーを利用したタンパク質分解制御
- Principal Investigator
  
  村田茂穂
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
Molecular mechanism for activation of RBR-type E3 ubiquitin ligasesPrincipal Investigator
- Principal Investigator
  
  YAMANO Koji
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science

All 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy2021
- Author(s)
  Kojima W, Yamano K, Kosako H, Imai K, Kikuchi R, Tanaka K, Matsuda N
- Journal Title
  
  Autophagy
  
  Volume: - Pages: 1-26
- DOI
  10.1080/15548627.2021.1874133
- NAID
  120007174412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11543, KAKENHI-PROJECT-20K06628, KAKENHI-PLANNED-18H05500, KAKENHI-PUBLICLY-19H04966, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18K06237
[Journal Article] Molecular mechanisms and physiological functions of mitophagy.2021
- Author(s)
  Onishi Mashun、Yamano Koji、Sato Miyuki、Matsuda Noriyuki、Okamoto Koji
- Journal Title
  
  EMBO J.
  
  Volume: 40 Pages: 1-1
- DOI
  10.15252/embj.2020104705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PUBLICLY-20H05324, KAKENHI-PROJECT-18H02435, KAKENHI-PROJECT-19F19816, KAKENHI-PROJECT-18K06237
[Journal Article] Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy.2020
- Author(s)
  Yamano Koji、Kikuchi Reika、Kojima Waka、Hayashida Ryota、Koyano Fumika、Kawawaki Junko、Shoda Takuji、Demizu Yosuke、Naito Mikihiko、Tanaka Keiji、Matsuda Noriyuki
- Journal Title
  
  J. Cell Biol.
  
  Volume: 219 Pages: 1-1
- DOI
  10.1083/jcb.201912144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-19K07009, KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-18H05502, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18K06237
[Journal Article] Two sides of a coin: physiological significance and molecular mechanisms for damage-induced mitochondrial localization of PINK1 and Parkin.2020
- Author(s)
  Matsuda Noriyuki、Yamano Koji
- Journal Title
  
  Neurosci. Res.
  
  Volume: in press Pages: 16-24
- DOI
  10.1016/j.neures.2020.03.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18K06237
[Journal Article] Two different axes CALCOCO2-RB1CC1 and OPTN-ATG9A initiate PRKN-mediated mitophagy.2020
- Author(s)
  Yamano Koji、Youle Richard J.
- Journal Title
  
  Autophagy
  
  Volume: 16 Pages: 2105-2107
- DOI
  10.1080/15548627.2020.1815457
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18K06237
[Journal Article] Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL.2019
- Author(s)
  Koyano, F., Yamano, K., Kosako, H., Tanaka, K., and Matsuda, N.
- Journal Title
  
  J Biol Chem.
  
  Volume: 294 Pages: 10300-10314
- DOI
  10.1074/jbc.ra118.006302
- NAID
  120006959752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-26000014, KAKENHI-PROJECT-18H02443
[Journal Article] Parkin-mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes.2019
- Author(s)
  Koyano, F., Yamano, K., Kosako, H., Kimura, K., Kimura, M., Fujiki, Y., Tanaka, K., and Matsuda, N.
- Journal Title
  
  EMBO Reports
  
  Volume: 20
- DOI
  10.15252/embr.201947728
- NAID
  120006942558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08635, KAKENHI-PROJECT-18K06237, KAKENHI-PROJECT-18K14708, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-17H03675, KAKENHI-PROJECT-26000014, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18H02443
[Journal Article] Endosomal Rab cycles regulate Parkin-mediated mitophagy.2018
- Author(s)
  Yamano, K., Wang, C., Sarraf, S. A., Munch, C., Kikuchi, R., Noda, N. N., Hizukuri, Y., Kanemaki, M. T., Harper, W., Tanaka, K., Matsuda, N., and Youle, R. J.
- Journal Title
  
  Elife
  
  Volume: 7
- DOI
  10.7554/elife.31326
- NAID
  120006457172
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15091, KAKENHI-PLANNED-25111004, KAKENHI-PROJECT-16K15095, KAKENHI-PROJECT-16K18545, KAKENHI-PROJECT-26000014, KAKENHI-PUBLICLY-18H04719, KAKENHI-PROJECT-18H02170, KAKENHI-PROJECT-18H02443
[Journal Article] Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30.2017
- Author(s)
  Sato, S., Okatsu, K., Saeki, Y., Yamano, K., Matsuda, M., Kaiho, A., Yamagata, A., Goto-Ito, S., Ishikawa, M., Hashimoto, Y., Tanaka, K., and Fukai, S.
- Journal Title
  
  Nat. Struct. Mol. Biol.
  
  Volume: 24 Pages: 911-919
- DOI
  10.1038/nsmb.3469
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15072, KAKENHI-PROJECT-25293027, KAKENHI-PROJECT-26293018, KAKENHI-PROJECT-16H04749, KAKENHI-PROJECT-16H04750, KAKENHI-PROJECT-15J10559, KAKENHI-PROJECT-16K18545, KAKENHI-PROJECT-26000014
[Journal Article] Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.2017
- Author(s)
  Matsuda, N., Kimura., M., Queliconi, B. B., Kojima, W., Mishima, M., Takagi, K., Koyano, F., Yamano, K., Mizushima, T., Ito, Y., and Tanaka, K.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Pages: 12816-12816
- DOI
  10.1038/s41598-017-13146-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H00847, KAKENHI-PUBLICLY-17H05887, KAKENHI-PUBLICLY-17H05888, KAKENHI-PROJECT-15H04339, KAKENHI-PROJECT-16F15387, KAKENHI-PROJECT-17J03737, KAKENHI-PROJECT-15K14494, KAKENHI-PROJECT-16K18545, KAKENHI-PROJECT-26000014
[Presentation] Critical Roles of Ubiquitin and Autophagy Adaptors in Mitochondria-Selective Degradation2020
- Author(s)
  Koji Yamano
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06237
[Presentation] Mitochondrial Degradation: Dance with Ubiquitin and Autophagy2019
- Author(s)
  Koji Yamano
- Organizer
  AUS-OsakaMito2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06237
[Presentation] ストレスに応答した損傷ミトコンドリアの選択的分解2019
- Author(s)
  山野晃史
- Organizer
  第14回日本臨床ストレス応答学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06237
[Presentation] Positive Feedback Ubiquitination Cycles upon Parkin-mediated Mitophagy2017
- Author(s)
  Koji Yamano
- Organizer
  2017 International Protein Metabolism & Disease Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18545
[Presentation] Positive Feedback Ubiquitylation Cycles upon Parkin-mediated Mitophagy2017
- Author(s)
  Koji Yamano
- Organizer
  OsakaMito2017 -International Workshop on Mitochondrial Dynamics-
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18545
[Presentation] ユビキチンコードによる損傷ミトコンドリアの標識2017
- Author(s)
  山野晃史, 松田憲之
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K18545
[Presentation] マイトファジーにおけるオートファゴソーム形成機構2016
- Author(s)
  山野晃史, 松田憲之, Richard J. Youle, 田中啓二
- Organizer
  第89回日本生化学会大会 3S01-4
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-16K18545
[Presentation] Autophagosome morphogenesis upon Parkin-mediated mitophagy2016
- Author(s)
  Koji Yamano, Richard J. Youle, Keiji Tanaka, and Noriyui Matsuda
- Organizer
  The 13th Conference of Asian Society for Mitochondrial Research and Medicine [ASMRM] and the 16th Conference of Japanese Society of Mitochondrial Research and Medicine [J-mit]
- Place of Presentation
  TKP Garden City Shinagawa, Tokyo
- Year and Date
  2016-11-01
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18545

1. 村田茂穂 (20344070)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. IMAI Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. MATSUDA Noriyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
4. NODA Nobuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SATO Ken

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. ISHIKAWA Minoru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. SAEKI Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. KAIHO Ai

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. SATO Yusuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. Okatsu Kei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. SYODA Takuji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 小迫英尊

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 檜作洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 鐘巻将人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 田中啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
16. 伊藤桜子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山形敦史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 伊藤隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 三島正規

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. QUELICONI BRUNO

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 小谷野史香

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 佐藤美由紀

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# of Collaborated Products: 1 results
23. 岡本浩二

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# of Collaborated Products: 1 results
24. 出水庸介

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# of Collaborated Products: 1 results
25. 内藤幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 伊藤拓水

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 藤木幸夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yamano koji 山野 晃史

YAMANO Koji 山野 晃史

Research Projects

Research Products

Co-Researchers

オートファジーアダプターをハブとした損傷ミトコンドリア分解機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstitution of Parkin activation and recruitment to target membranePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ケモテクノロジーを利用したタンパク質分解制御

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism for activation of RBR-type E3 ubiquitin ligasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mammalian BCAS3 and C16orf70 associate with the phagophore assembly site in response to selective and non-selective autophagy2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Molecular mechanisms and physiological functions of mitophagy.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical role of mitochondrial ubiquitination and the OPTN-ATG9A axis in mitophagy.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two sides of a coin: physiological significance and molecular mechanisms for damage-induced mitochondrial localization of PINK1 and Parkin.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Two different axes CALCOCO2-RB1CC1 and OPTN-ATG9A initiate PRKN-mediated mitophagy.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Parkin-mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Endosomal Rab cycles regulate Parkin-mediated mitophagy.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.2017

Author(s)

yamano koji 山野晃史

YAMANO Koji 山野晃史