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Kojima Fumiaki  小島 史章

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KOJIMA Fumiaki  小島 史章

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Researcher Number 30550545
Other IDs
Affiliation (Current) 2025: 北里大学, 医療衛生学部, 准教授
Affiliation (based on the past Project Information) *help 2014 – 2024: 北里大学, 医療衛生学部, 准教授
2010 – 2013: 旭川医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47040:Pharmacology-related / General pharmacology / Neurochemistry/Neuropharmacology
Except Principal Investigator
General pharmacology / Rehabilitation science/Welfare engineering
Keywords
Principal Investigator
プロスタノイド / 皮膚免疫 / 乾癬 / 遺伝子欠損マウス / 多発性硬化症 / プロスタグランジンE2 / 受容体欠損マウス / ミクログリア / EP4 / プロスタグロンジンE2 / 脳血栓症 / 中枢・末梢神経薬理学 … More
Except Principal Investigator
… More 心筋梗塞 / プロスタノイド / リハビリテーション科学 / 神経科学 / 生理学 / 脳・神経 / 心虚血再還流傷害 / 心臓 / 糖質コルチコイド / 血小板 / 脳血栓 / 腎線維化 / 循環器疾患 / 循環器系疾患 / 循環器 / トロンボキサン / プロスタグランジン Less
  • Research Projects

    (8 results)
  • Research Products

    (123 results)
  • Co-Researchers

    (10 People)
  •  プロスタグランジンE合成酵素のトリプルネガティブ乳がんにおける役割解明Principal Investigator

    • Principal Investigator
      小島 史章
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kitasato University
  •  Role of microsomal prostaglandin E synthase-1 in the development of psoriasis.Principal Investigator

    • Principal Investigator
      小島 史章
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Kitasato University
  •  Role of prostanoid in demyelination and remyelination.Principal Investigator

    • Principal Investigator
      Kojima Fumiaki
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kitasato University
  •  The study on reorganization of neuronal circuit function after cerebral infarction with or without limitation of movement

    • Principal Investigator
      Ishibashi Hitoshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Kitasato University
  •  Regulation of cardiac prostanoid synthesis by glucocorticoid and its pathophysiological meaning

    • Principal Investigator
      USHIKUBI Fumitaka
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Asahikawa Medical College
  •  Role of the prostanoid in cisplatin-induced nephropathyPrincipal Investigator

    • Principal Investigator
      KOJIMA Fumiaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kitasato University
      Asahikawa Medical College
  •  Roles of the prostanoids in the pathogenesis of cardiovascular diseases

    • Principal Investigator
      USHIKUBI Fumitaka
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Asahikawa Medical College
  •  The roles of prostanoid receptor in cerebral infarctionPrincipal Investigator

    • Principal Investigator
      KOJIMA Fumiaki
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Asahikawa Medical College

All 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Book

  • [Book] Arachidonic Acid: Sources, Biosynthesis and Health Effects. "Effects of Adipokines on Prostaglandin E2 Production by Rheumatoid Synovial Fibroblasts."2014

    • Author(s)
      Natsuko Kusunoki, Fumiaki Kojima, Shinichi Kawai.
    • Publisher
      Nova Science Publishers, Inc
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Book] Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in the pathophysiology of osteoarthritis, 'Understanding Osteoarthritis from Bench to Bedside'2011

    • Author(s)
      Fumiaki Kojima, Mohit Kapoor
    • Publisher
      Edited by Johanne Martel-Pelletier & Jean-Pierre Pelletier. Research Signpost
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes.2023

    • Author(s)
      Kawakami Fumitaka、Imai Motoki、Isaka Yuki、Cookson Mark R.、Maruyama Hiroko、Kubo Makoto、Farrer Matthew J.、Kanzaki Makoto、Kawashima Rei、Maekawa Tatsunori、Tamaki Shun、Kurosaki Yoshifumi、Kojima Fumiaki、Ohba Kenichi、Ichikawa Takafumi
    • Journal Title

      FEBS Open Bio

      Volume: 13 Issue: 12 Pages: 2200-2214

    • DOI

      10.1002/2211-5463.13717

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06603, KAKENHI-PROJECT-22K07993, KAKENHI-PROJECT-23K06874, KAKENHI-PROJECT-23K07422, KAKENHI-PROJECT-20K08294, KAKENHI-PROJECT-21H04857
  • [Journal Article] The KCNQ channel inhibitor XE991 suppresses nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglion neurons2022

    • Author(s)
      Sato Aya、Kojima Fumiaki、Hayashi Toru、Arichi Shiho、Maruo Yoshihiro、Ishibashi Hitoshi、Eto Kei
    • Journal Title

      Pharmacological Reports

      Volume: 74 Issue: 4 Pages: 745-751

    • DOI

      10.1007/s43440-022-00375-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K06603, KAKENHI-PROJECT-19K07287
  • [Journal Article] Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate?induced colitis in mice lacking microsomal prostaglandin E synthase-12022

    • Author(s)
      Kojima Fumiaki、Sekiya Hiroki、Hioki Yuka、Kashiwagi Hitoshi、Kubo Makoto、Nakamura Masaki、Maehana Shotaro、Imamichi Yoshitaka、Yuhki Koh-ichi、Ushikubi Fumitaka、Kitasato Hidero、Ichikawa Takafumi
    • Journal Title

      Inflammation and Regeneration

      Volume: 42 Issue: 1 Pages: 1-24

    • DOI

      10.1186/s41232-021-00188-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-20K08294, KAKENHI-PROJECT-21K06603
  • [Journal Article] Complete genome sequencing and comparative genomic analysis of KPC-2-producing Klebsiella pneumoniae isolated from a hospital sewage water in Japan.2021

    • Author(s)
      Ryotaro Eda, Shotaro Maehana, Aki Hirabayashi, Masaki Nakamura, Takashi Furukawa, Shinsuke Ikeda, Kouji Sakai, Fumiaki Kojima, Kazunari Sei, Masato Suzuki, Hidero Kitasato.
    • Journal Title

      J Glob Antimicrob Resist.

      Volume: 24 Pages: 180-182

    • DOI

      10.1016/j.jgar.2020.12.007

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-19K04668, KAKENHI-PROJECT-20K07509, KAKENHI-PROJECT-18K04645
  • [Journal Article] Natural factories that manufacture antimicrobial resistance genes: quadruple blaGES-carrying plasmids in Aeromonas and Pseudomonas species.2021

    • Author(s)
      Shotaro Maehana, Ryotaro Eda, Aki Hirabayashi, Nagi Niida, Masaki Nakamura, Takashi Furukawa, Shinsuke Ikeda, Fumiaki Kojima, Kouji Sakai, Kazunari Sei, Hidero Kitasato, Masato Suzuki.
    • Journal Title

      Int J Antimicrob Agents.

      Volume: 28 Issue: 5 Pages: 106327-106327

    • DOI

      10.1016/j.ijantimicag.2021.106327

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-19K04668, KAKENHI-PROJECT-20K07509
  • [Journal Article] Panton-Valentine Leukocidin Induces Cytokine Release and Cytotoxicity Mediated by the C5a Receptor on Rabbit Alveolar Macrophages2021

    • Author(s)
      Shinya Harada, Hayato Kawada, Shotaro Maehana, Hidehito Matsui, Makoto Kubo, Fumiaki Kojima, Hidero Kitasato, Masato Katagiri.
    • Journal Title

      Jpn J Infect Dis

      Volume: 74 Issue: 4 Pages: 352-358

    • DOI

      10.7883/yoken.JJID.2020.657

    • NAID

      130008066545

    • ISSN
      1344-6304, 1884-2836
    • Year and Date
      2021-07-31
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance <i>via</i> Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes2020

    • Author(s)
      Motoki Imai, Fumitaka Kawakami, Makoto Kubo, Makoto Kanzaki, Hiroko Maruyama, Rei Kawashima, Tatsunori Maekawa, Yoshifumi Kurosaki, Fumiaki Kojima, Takafumi Ichikawa.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 43 Issue: 11 Pages: 1660-1668

    • DOI

      10.1248/bpb.b20-00377

    • NAID

      130007934043

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2020-11-01
    • Language
      English
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-19K07944, KAKENHI-PROJECT-19K08379, KAKENHI-PROJECT-20K08294, KAKENHI-PROJECT-17K09392, KAKENHI-PROJECT-20H04118
  • [Journal Article] Real-time visualization of intratumoral necrosis using split-luciferase reconstitution by protein trans-splicing.2020

    • Author(s)
      Go Kagiya Ayaka Sato Ryohei Ogawa Masanori Hatashita Mana Kato Makoto Kubo Fumiaki Kojima Fumitaka Kawakami Yukari Nishimura Naoya Abe Fuminori Hyodo.
    • Journal Title

      Mol Ther Oncolytics.

      Volume: 20 Pages: 48-58

    • DOI

      10.1016/j.omto.2020.12.001

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-18K07768, KAKENHI-PROJECT-21K07654
  • [Journal Article] Inhibition of Interleukin-6 Signaling Attenuates Aortitis, Left Ventricular Hypertrophy and Arthritis in Interleukin-1 Receptor Antagonist Deficient Mice.2020

    • Author(s)
      Yoshiko Hada, Haruhito A. Uchida, Tomoyuki Mukai, Fumiaki Kojima, Masashi Yoshida, Hidemi Takeuchi, Yuki Kakio, Nozomu Otaka,Yoshitaka Morita, Jun Wada.
    • Journal Title

      Clin. Sci. (Lond).

      Volume: 134 Issue: 20 Pages: 2771-2787

    • DOI

      10.1042/cs20201036

    • NAID

      120007168219

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-19H03675, KAKENHI-PROJECT-18K08398
  • [Journal Article] Histamine depolarizes rat intracardiac ganglion neurons through the activation of TRPC non-selective cation channels.2020

    • Author(s)
      Aya Sato, Shiho Arichi, Fumiaki Kojima, Toru Hayashi, Tatsuko Ohba, Dennis Lawrence Cheung, Kei Eto, Madoka Narushima, Hideji Murakoshi, Yoshihiro Maruo, Yuichi Kadoya, Junichi Nabekura, Hitoshi Ishibashi.
    • Journal Title

      Eur J Pharmacol.

      Volume: 886 Pages: 173536-173536

    • DOI

      10.1016/j.ejphar.2020.173536

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-18K07818, KAKENHI-PROJECT-19K07287, KAKENHI-PROJECT-17H01530, KAKENHI-PUBLICLY-19H05434, KAKENHI-PROJECT-20H00500
  • [Journal Article] Prostaglandin F2α facilitates platelet activation by acting on prostaglandin E2 receptor subtype EP3 and thromboxane A2 receptor TP in mice.2019

    • Author(s)
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Shuh Narumiya, Fumitaka Ushikubi.
    • Journal Title

      Thrombosis and Haemostasis.

      Volume: in press

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] Prostaglandin F2α Facilitates Platelet Activation by Acting on Prostaglandin E2 Receptor Subtype EP3 and Thromboxane A2 Receptor TP in Mice2019

    • Author(s)
      Kashiwagi Hitoshi、Yuhki Koh-ichi、Imamichi Yoshitaka、Kojima Fumiaki、Kumei Shima、Tasaki Yoshikazu、Narumiya Shuh、Ushikubi Fumitaka
    • Journal Title

      Thrombosis and Haemostasis

      Volume: 119 Issue: 08 Pages: 1311-1320

    • DOI

      10.1055/s-0039-1688906

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-17K11214, KAKENHI-PROJECT-18K15739
  • [Journal Article] Interleukin-24 Transduction Modulates Human Prostate Cancer Malignancy Mediated by Regulation of Anchorage Dependence2019

    • Author(s)
      MAEHANA SHOTARO、MATSUMOTO YUTA、KOJIMA FUMIAKI、KITASATO HIDERO
    • Journal Title

      Anticancer Research

      Volume: 39 Issue: 7 Pages: 3719-3725

    • DOI

      10.21873/anticanres.13520

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K08604, KAKENHI-PROJECT-19K16841
  • [Journal Article] Roles of prostanoids in the regulation of platelet function.2018

    • Author(s)
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Shuh Narumiya, Fumitaka Ushikubi.
    • Journal Title

      Thromb Haemost Res.

      Volume: 2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] Prostaglandin I2 suppresses the development of diet-induced nonalcoholic steatohepatitis in mice2018

    • Author(s)
      Kumei Shima、Yuhki Koh-Ichi、Kojima Fumiaki、Kashiwagi Hitoshi、Imamichi Yoshitaka、Okumura Toshikatsu、Narumiya Shuh、Ushikubi Fumitaka
    • Journal Title

      The FASEB Journal

      Volume: 32 Issue: 5 Pages: 2354-2365

    • DOI

      10.1096/fj.201700590r

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] Cigarette Smoke Extract Inhibits Platelet Aggregation by Suppressing Cyclooxygenase Activity2017

    • Author(s)
      Kashiwagi Hitoshi、Yuhki Koh-ichi、Imamichi Yoshitaka、Kojima Fumiaki、Kumei Shima、Higashi Tsunehito、Horinouchi Takahiro、Miwa Soichi、Narumiya Shuh、Ushikubi Fumitaka
    • Journal Title

      TH Open

      Volume: 01 Issue: 02 Pages: e122-e129

    • DOI

      10.1055/s-0037-1607979

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] mPGES1-Dependent Prostaglandin E2(PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2Production2017

    • Author(s)
      Maseda Damian、Johnson Elizabeth M.、Nyhoff Lindsay E.、Baron Bridgette、Kojima Fumiaki、Wilhelm Ashley J.、Ward Martin R.、Woodward Jerold G.、Brand David D.、Crofford Leslie J.
    • Journal Title

      The Journal of Immunology

      Volume: 200 Issue: 2 Pages: 725-736

    • DOI

      10.4049/jimmunol.1601808

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Journal Article] The novel prostaglandin I2 mimetic ONO-1301 escapes desensitization in an anti-platelet effect due to its inhibitory action on thromboxane A2 synthesis in mice.2015

    • Author(s)
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Shima Kumei, Yoshiki Sakai, Shuh Narumiya Fumitaka Ushikubi.
    • Journal Title

      J Pharmacol Exp Ther.

      Volume: 353 Pages: 269-278

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] 虚血による神経障害の分子メカニズム プロスタノイドの役割2014

    • Author(s)
      小島史章、結城幸一、柏木仁、粂井志麻、牛首文隆
    • Journal Title

      日本臨牀

      Volume: 72 Pages: 121-125

    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] Reduced T-cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by non-hematopoietic cells.2013

    • Author(s)
      Fumiaki Kojima, Andrey Frolov, Rahul Matnani, Jerold G. Woodward, Leslie J. Crofford
    • Journal Title

      J Immunol.

      Volume: 191 Issue: 10 Pages: 4979-4988

    • DOI

      10.4049/jimmunol.1301942

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] PG/LT system and inflammation2012

    • Author(s)
      Fumiaki Kojima, Koh-ichi Yuhki, Hitoshi Kashiwagi, Shima Kumei, Fumitaka Ushikubi
    • Journal Title

      Nippon Rinsho

      Volume: 70 Pages: 231-235

    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] エイコサノイド2012

    • Author(s)
      結城幸一、柏木仁、小島史章、牛首文隆
    • Journal Title

      臨床検査

      Volume: 56 Pages: 145-150

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice.2012

    • Author(s)
      Nakagawa N, Yuhki K, Kawabe J, Fujino T, Takahata O, Kabara M, Abe K, Kojima F, Kashiwagi H, Hasebe N, Kikuchi K, Sugimoto Y, Narumiya S, Ushikubi F.
    • Journal Title

      Kidney Int.

      Volume: 82 Pages: 158-171

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] The intrinsic prostaglandin E_2-EP_4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice2012

    • Author(s)
      Nakagawa N, Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
    • Volume
      82
    • Pages
      158-171
    • Data Source
      KAKENHI-PROJECT-22390045
  • [Journal Article] プロスタノイド受容体欠損マウスを用いた心血管系におけるプロスタノイドの作用2012

    • Author(s)
      結城幸一、柏木仁、小島史章、牛首文隆
    • Journal Title

      血栓と循環

      Volume: 20 Pages: 4-8

    • Data Source
      KAKENHI-PROJECT-24790246
  • [Journal Article] Potential role of microsomal prostaglandin E synthase-1 in rheumatoid arthritis.2011

    • Author(s)
      Fumiaki Kojima
    • Journal Title

      Inflammation and Regeneration.

      Volume: 31 Pages: 157-166

    • NAID

      130004943782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular system: Novel insights from knockout mouse studies2011

    • Author(s)
      Yuhki K, Kojima F, Kashiwagi H, Ushikubi F, et al
    • Journal Title

      Pharmacol Ther

      Volume: 129 Pages: 195-205

    • Data Source
      KAKENHI-PROJECT-22390045
  • [Journal Article] Potential role of microsomal prostaglandin E synthase-1 in rheumatoid arthritis2011

    • Author(s)
      Fumiaki Kojima, Rahul G. Matnani, Shinichi Kawai, Fumitaka Ushikubi, Leslie J. Crofford
    • Journal Title

      Inflamm Regen

      Volume: 31 Pages: 157-166

    • NAID

      130004943782

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Genetic deletion of mPGES-1 abolishes PGE2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration2011

    • Author(s)
      Seetha U. Monrad, Fumiaki Kojima, Mohit Kapoor, Emma L. Kuan, Sujata Sarkar, Gwendalyn Randolph, Leslie J. Crofford
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids

      Volume: 84 Pages: 113-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] mPGES-1 null mice are resistant to bleomycin-induced skin fibrosis2011

    • Author(s)
      Matthew R McCann, Roxana Monemdjou, Parisa Ghassemi-Kakroodi, Hassan Fahmi, Gemma Perez, Shangxi Liu, Xu Shi-wen, Sunil K Parapuram, Fumiaki Kojima, Christopher P Denton, David J Abraham, Johanne Martel-Pelletier, Leslie J Crofford, Andrew Leask, Mohit Kapoor
    • Journal Title

      Arthritis Res Ther

      Volume: 13

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] III.病因と病態生理メタボリックシンドローム発症にかかわるその他の液性および神経性因子内因性カンナビノイド系2011

    • Author(s)
      結城幸一、柏木仁、小島史章、牛首文隆
    • Journal Title

      日本臨牀

      Volume: 増刊号69 Pages: 331-335

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Genetic deletion of mPGES-1 abolishes PGE_2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration.2011

    • Author(s)
      Seetha U.Monrad, Fumiaki Kojima
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids.

      Volume: 84 Pages: 113-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Potential roles of microsomal prostaglandin E synthase-1 in rheumatoid arthritis2011

    • Author(s)
      Kojima F, Ushikubi F, Crofford LJ, et al
    • Journal Title

      Inflamm Regen

      Volume: 31 Pages: 157-166

    • NAID

      130004943782

    • Data Source
      KAKENHI-PROJECT-22390045
  • [Journal Article] Genetic deletion of mPGES-1 abolishes PGE_2 production in murine dend ritic cells and alters the cjrtokine profile, but does not affect maturation or migration2011

    • Author(s)
      Seetha U.Monrad, Fumiaki Kojima
    • Journal Title

      Prostaglandins Leukot Essent Fatty Acids

      Volume: 84 Pages: 113-121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Somatic cell plasticity and Niemann-Pick Type C2 protein : Fibroblast activation2011

    • Author(s)
      Chad Csepeggi, Min Jiang, Fumiaki Kojima, Leslie J. Crofford, Andrey Frolov
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 2078-87

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases : Novel insights from knockout mouse studies2011

    • Author(s)
      Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Jun-ichi Kawabe, Takayuki Fujino, Shuh Narumiya, Fumitaka Ushikubi
    • Journal Title

      Pharmacol Ther

      Volume: 129 Pages: 195-205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] プロスタノイド受容体ノックアウトマウス2011

    • Author(s)
      結城幸一、柏木仁、小島史章、牛首文隆
    • Journal Title

      The Lipid

      Volume: 22 Pages: 4-11

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Selective activation of the prostaglandin E2 receptor subtype EP2 or EP4 leads to inhibition of platelet aggregation2010

    • Author(s)
      Shuhko Kuriyama, Hitoshi Kashiwagi, Koh-ichi Yuhki, Fumiaki Kojima, Takehiro Yamada, Takayuki Fujino, Akiyoshi Hara, Koji Takayama, Takayuki Maruyama, Akitoshi Yoshida, Shuh Narumiya, Fumitaka Ushikubi
    • Journal Title

      Thromb Haemost

      Volume: 104 Pages: 796-803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] プロスタグランジンE1およびE2とその代謝産物2010

    • Author(s)
      小島史章、結城幸一、柏木仁、牛首文隆
    • Journal Title

      日本臨牀

      Volume: 68 Pages: 20-24

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Selective activation of the prostaglandin E_2 receptor subtype EP_2 or EP_4 leads to inhibition of platelet aggregation2010

    • Author(s)
      Kuriyama S, Kashiwagi H, Yuhki K, Kojima F, Ushikubi F, et al
    • Journal Title

      Thromb Haemost

      Volume: 104 Pages: 796-803

    • Data Source
      KAKENHI-PROJECT-22390045
  • [Journal Article] 炎症・免疫分野とノーベル賞1992年生理・医学賞:生体制御機構としての可逆的蛋白リン酸化の発見(受賞者:Edmond H. Fischer, Edwin G. Krebs)・1994年生理・医学賞:G蛋白質およびそれらの細胞内情報伝達における役割(受賞者:Alfred G. Gilman, Martin Rodbell).2010

    • Author(s)
      結城幸一、小島史章、柏木仁、牛首文隆
    • Journal Title

      炎症と免疫

      Volume: 18 Pages: 73-78

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] プロスタグランジンI2とその代謝産物2010

    • Author(s)
      結城幸一、小島史章、柏木仁、牛首文隆
    • Journal Title

      日本臨牀

      Volume: 68 Pages: 29-32

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Adiponectin Stimulates Prostaglandin E2 Production in Rheumatoid Synovial Fibroblasts2010

    • Author(s)
      Natsuko Kusunoki, Kanako Kitahara, Fumiaki Kojima, Nahoko Tanaka, Kaichi Kaneko, Hirahito Endo, Toru Suguro, Shinichi Kawai
    • Journal Title

      Arthritis Rheum

      Volume: 62 Pages: 1641-1649

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] Roles of prostanoids in the pathogenesis of cardiovascular diseases2010

    • Author(s)
      Koh-ichi Yuhki, Hitoshi Kashiwagi, Fumiaki Kojima, Jun-ichi Kawabe, Fumitaka Ushikubi
    • Journal Title

      Int. Angiol

      Volume: 29 Pages: 19-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] プロスタグランジンE_1およびE_2とその代謝産物2010

    • Author(s)
      小島史章
    • Journal Title

      日本臨牀

      Volume: 68 Pages: 20-24

    • Data Source
      KAKENHI-PROJECT-22700388
  • [Journal Article] The intrinsic prostaglandin E2-EP4 system of the renal tubular epithelium limits the development of tubulointerstitial fibrosis in mice

    • Author(s)
      Naoki Nakagawa, Koh-ichi Yuhki, Jun-ichi Kawabe, Takayuki Fujino, Osamu Takahata, Maki Kabara, Kazutoshi Abe, Fumiaki Kojima, Hitoshi Kashiwagi, Naoyuki Hasebe, Kenjiro Kikuchi, Yukihiko Sugimoto, Shuh Narumiya, Fumitaka Ushikubi
    • Journal Title

      Kidney Int

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Role of the microsomal prostaglandin E synthase-1 in psoriasis.2023

    • Author(s)
      Yuka Hioki, Hiroki Enomoto, Yu Onodera, Saki Miura, Hikaru Itabashi, Yoshiko Iizuka, Shotaro Maehana, Makoto Kubo, Takafumi Ichikawa, Fumiaki Kojima.
    • Organizer
      第143回 日本薬学会年会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 2022年度における医療排水および下水処理場から検出される広域β-ラクタム耐性菌の実態2023

    • Author(s)
      小山真子、石村菜穂子、江田諒太郎、伊澤紘輝、小島史章、久保誠、前花祥太郎
    • Organizer
      第17回 日本臨床検査学教育学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] イミキモド誘発乾癬様病態に対して膜型プロスタグランジンE合成酵素-1は保護的に働く.2023

    • Author(s)
      日置優花、西村里菜、倉島杏奈、榎本大樹、飯塚佳子、前花祥太郎、久保 誠、市川尊文、小島史章.
    • Organizer
      第147回 日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] Genetic deletion of microsomal prostaglandin E synthase-1 suppresses cuprizone-induced demyelination and motor dysfunction in mice2023

    • Author(s)
      Yuka Hioki, Fumiaki Kojima, Riko Mutaguchi, Kei Eto, Masanori Ogata, Sachie Sasaki-Hamada, Takafumi Ichikawa, Hitoshi Ishibashi
    • Organizer
      Neuroscience 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] Role of microsomal prostaglandin E synthase-1 in skin inflammation and T-cell immune response of imiquimod-induced psoriasis in mice2023

    • Author(s)
      Yuka Hioki, Mayu Aono, Ayana Kijino, Yuga Kurashina, Anna Kurashima, Rina Nishimura, Yoshiko Iizuka, Shotaro Maehana, Makoto Kubo, Takafumi Ichikawa, Fumiaki Kojima
    • Organizer
      第97回 薬理学会年会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 医療排水より検出されたメロペネム・チゲサイクリン両剤耐性菌の薬剤耐性の解析2023

    • Author(s)
      石村菜穂子、江田諒太郎,伊澤紘輝、小山真子、鈴木仁人、小島史章、久保誠、前花祥太郎
    • Organizer
      第17回 日本臨床検査学教育学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 乾癬様病態モデルを用いた皮膚における膜型プロスタグランジンE合成酵素-1の役割解析2023

    • Author(s)
      日置優花、西村里菜、倉島杏奈、青野真夕、雉野朱那、飯塚佳子、前花祥太郎、久保誠、市川尊文、小島史章
    • Organizer
      第17回 日本臨床検査学教育学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] T細胞免疫に着目したイミキモド誘発乾癬病態における膜型プロスタグランジンE合成酵素-1の役割解析2023

    • Author(s)
      日置優花、西村里菜、倉島杏奈、倉科勇雅、青野真夕、雉野朱那、飯塚佳子、前花祥太郎、久保誠、市川尊文、小島史章
    • Organizer
      第149回 日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 膜型プロスタグランジンE合成酵素-1の乾癬病態に対する保護的作用2023

    • Author(s)
      日置優花、西村里菜、倉島杏奈、榎本大樹、飯塚佳子、前花祥太郎、久保 誠、市川尊文、小島史章
    • Organizer
      第44回 日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 乾癬病態における膜型プロスタグランジンE合成酵素-1の役割の解析2023

    • Author(s)
      日置優花、西村里菜、倉島杏奈、倉科勇雅、青野真夕、雉野朱那、飯塚佳子、前花祥太郎、久保 誠、市川尊文、小島史章
    • Organizer
      第36回 北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 関東の臨床および病院排水から得られたIMP-1産生Enterobacter属の比較解析2022

    • Author(s)
      石村菜穂子、江田諒太郎、鈴木仁人、小島史章、北里英郎、前花祥太郎.
    • Organizer
      第16回日本臨床検査学教育学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 臨床および病院排水から得られたIMP-1産生Enterobacter属の比較解析.2022

    • Author(s)
      石村菜穂子、江田諒太郎、鈴木仁人、小島史章、前花祥太郎、久保 誠.
    • Organizer
      第35回北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] Role of the microsomal prostaglandin E synthase-1 in imiquimod-induced psoriasis-like skin inflammation.2022

    • Author(s)
      Yuka Hioki, Hiroki Enomoto, Saki Miura, Yu Onodera, Hikaru Itabashi, Yoshiko Iizuka, Shotaro Maehana, Makoto Kubo, Hidero Kitasato, Takafumi Ichikawa, Fumiaki Kojima.
    • Organizer
      第96回 薬理学会年会・第43回 臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] デキストラン硫酸ナトリウム誘発腸炎におけるT細胞免疫系の制御を介した膜型プロスタグランジンE合成酵素-1の役割2022

    • Author(s)
      日置優花、関谷広樹、久保 誠、牛首文隆、北里英郎、市川尊文、小島史章.
    • Organizer
      第43回日本炎症・再生医学会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] ウサギ肺胞マクロファージ(AM)に対するPanton-Valentine leukocidin(PVL)の作用2022

    • Author(s)
      原田真也、川田逸人、前花祥太郎、松井秀仁、久保 誠、小島史章、北里英郎、片桐真人、横場正典.
    • Organizer
      第62回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 膜型プロスタグランジンE合成酵素-1欠損マウスを用いたイミキモド誘発乾癬様病態の解析2022

    • Author(s)
      日置優花、榎本大樹、三浦早貴、小野寺 優、飯塚佳子、前花祥太郎、久保 誠、北里英郎、市川尊文、小島史章.
    • Organizer
      第35回北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] デキストラン硫酸ナトリウム誘発腸炎モデルマウスを用いた炎症性腸疾患における膜型プロスタグランジンE合成酵素-1の役割解析2022

    • Author(s)
      日置優花、関谷広樹、久保誠、牛首文隆、北里英郎、市川尊文、小島史章.
    • Organizer
      第146回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] プロスタグランジンE2生合成系に着目した乾癬様病態モデルマウスの病態解析2022

    • Author(s)
      日置優花、榎本大樹、三浦早貴、小野寺優、久保誠、飯塚佳子、前花祥太郎、北里英郎、市川尊文、小島史章.
    • Organizer
      第16回日本臨床検査学教育学会学術大会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] ウサギ肺胞マクロファージ(AM)を用いたPanton-Valentine leukocidin(PVL)の作用2021

    • Author(s)
      原田真也, 川田逸人, 前花祥太郎, 松井秀仁, 久保 誠, 小島史章, 北里英郎, 片桐真人
    • Organizer
      第61回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 腸管炎症・免疫系におけるプロスタグランジンE合成酵素の役割2021

    • Author(s)
      小島史章
    • Organizer
      第13回 北里大学医療衛生学部附属再生医療細胞デザイン研究施設シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Action of Panton-Valentine leukocidin on rabbit alveolar macrophages.2021

    • Author(s)
      原田真也、川田逸人、前花祥太郎、松井秀仁、久保 誠、小島史章、北里英郎、片桐真人、横場正典.
    • Organizer
      The 25th Congress of the Asian Pacific Society of Respirology.
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] T細胞免疫系の制御を介した膜型プロスタグランジンE合成酵素-1のデキストラン硫酸ナトリウム誘発腸炎に対する保護的役割2021

    • Author(s)
      日置優花、関谷広樹、三島絵梨香、北浦咲耶子、久保誠、北里英郎、市川尊文、小島史章.
    • Organizer
      145回 薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Action of Panton-Valentine leukocidin on rabbit alveolar macrophages.2021

    • Author(s)
      原田真也、川田逸人、前花祥太郎、松井秀仁、久保 誠、小島史章、北里英郎、片桐真人、横場正典.
    • Organizer
      The 25th Congress of the Asian Pacific Society of Respirology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] T細胞免疫系の制御を介した膜型プロスタグランジンE合成酵素-1のデキストラン硫酸ナトリウム誘発腸炎に対する保護的役割2021

    • Author(s)
      日置優花、関谷広樹、三島絵梨香、北浦咲耶子、久保誠、北里英郎、市川尊文、小島史章.
    • Organizer
      145回 薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 放射線による腫瘍内低酸素細胞アポトーシスの可視化とその経時変化2021

    • Author(s)
      青柳美希、小川良平、畑下昌範、兵藤文紀、久保誠、小島史章、川上文貴、鍵谷豪.
    • Organizer
      北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] ウサギ肺胞マクロファージ(AM)を用いたPanton-Valentine leukocidin(PVL)の作用2021

    • Author(s)
      原田真也, 川田逸人, 前花祥太郎, 松井秀仁, 久保 誠, 小島史章, 北里英郎, 片桐真人
    • Organizer
      第61回日本呼吸器学会学術講演会
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] 放射線による腫瘍内低酸素細胞アポトーシスの可視化とその経時変化2021

    • Author(s)
      青柳美希、小川良平、畑下昌範、兵藤文紀、久保誠、小島史章、川上文貴、鍵谷豪.
    • Organizer
      北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-21K06603
  • [Presentation] The prostaglandin E2-EP4 system protects the liver in Concanavalin A-induced hepatitis.2020

    • Author(s)
      Yoshitaka Imamichi, Koh-ichi Yuhki, Hitoshi Kashiwagi, Shima Kumei, Katsura Nakanishi, Fumiaki Kojima, Shuh Narumiya, Fumitaka Ushikubi.
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Inhibition of Interleukin-6 Signaling Attenuates Aortitis and Cardiomyocyte Hypertrophy in Interleukin-1 Receptor Antagonist Deficient Mice.2020

    • Author(s)
      Yoshiko Hada, Haruhito A. Uchida, Tomoyuki Mukai, Fumiaki Kojima, Nozomu Otaka, Hidemi Takeuchi, Masashi Yoshida, Yoshitaka Morita, Yoichiro Iwakura, Jun Wada.
    • Organizer
      Arteriosclerosis, Thrombosis and Vascular Biology / Peripheral Vascular Disease (ATVB|PVD) 2020 Scientific Sessions (ATVB/PVD 2020)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Role of the microsomal prostaglandin E synthase-1 in cuprizone-induced demyelination and motor dysfunction.2020

    • Author(s)
      Fumiaki Kojima, Hiroki Sekiya, Hayato Kawada, Hitoshi Kashiwagi, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumitaka Ushikubi, Hidero Kitasato, Takafumi Ichikawa.
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Role of the prostaglandin E2-EP4 system in Concanavalin A-induced hepatitis2019

    • Author(s)
      Yoshitaka Imamichi1, Ko-ichi Yuhki, Hitoshi Kashiwagi, Shima Kumei, Fumiaki Kojima, Katsura Nakanishi, Shuh Narumiya, Fumitaka Ushikubi
    • Organizer
      日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] プロスタノイド生合成系に着目した炎症性腸疾患の病態形成機序の解明2019

    • Author(s)
      小島史章
    • Organizer
      第32回北里大学大学院医療系研究科研究フォーラム
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Inhibition of Interleukin-6 Signaling on Aortitis in Interleukin-1 Receptor Antagonist Deficient Mice.2019

    • Author(s)
      Yoshiko Hada, Haruhito A. Uchida, Tomoyuki Mukai, Fumiaki Kojima, Nozomu Otaka, Yasuhiro Onishi, Yoshitaka Morita, Yoichiro Iwakura, Jun Wada.
    • Organizer
      Arteriosclerosis, Thrombosis and Vascular Biology / Peripheral Vascular Disease (ATVB|PVD) 2019 Scientific Sessions (ATVB/PVD 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 炎症性腸疾患における膜型プロスタグランジンE合成酵素-1の役割2018

    • Author(s)
      関谷広樹、守田なつみ、中村仁美、青木 結、久保 誠、市川尊文、北里英郎、小島史章
    • Organizer
      北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Potentiating effect of prostaglandin F2a on platelet aggregation in mice.2018

    • Author(s)
      Hitoshi Kashiwagi, Koh-ichi Yuhki, Yoshitaka Imamichi, Fumiaki Kojima, Shima Kumei, Shuh Narumiya, Fumitaka Ushikubi.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] Up-regulation of colonic Th1/Th17 cytokines is associated with increased severity of experimental colitis in mice lacking microsomal prostaglandin E synthase-1.2018

    • Author(s)
      Hiroki Sekiya, Masaki Nakamura, Shotaro Maehana, Hitoshi Kashiwagi, Yoshitaka Imamichi, Koh-ichi Yuhki, Fumitaka Ushikubi, Takafumi Ichikawa, Hidero Kitasato, Fumiaki Kojima.
    • Organizer
      18th World Congress of Basic and Clinical Pharmacology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] トリニトロベンゼンスルホン酸誘発腸炎モデルにおける膜型プロスタグランジンE合成酵素-1の保護的役割2017

    • Author(s)
      関谷広樹、河喜多智美、中村正樹、前花祥太郎、市川尊文、北里英郎、小島史章
    • Organizer
      炎症再生医学会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] デキストラン硫酸ナトリウム誘発腸炎モデルにおけるTh1/Th17系の制御を介したmPGES-1/PGE2系の保護的役割2017

    • Author(s)
      関谷広樹、市川尊文、北里英郎、小島史章
    • Organizer
      炎症再生医学会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 炎症性腸疾患様マウスモデルを用いた膜型プロスタグランジンE合成酵素-1の役割2017

    • Author(s)
      関谷広樹、鈴木沙織、京極美帆、倉本大輔、市川尊文、北里英郎、小島史章
    • Organizer
      日本炎症性腸疾患学会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 炎症性腸疾患におけるTh17/Th1系の制御を介した膜型プロスタグランジンE合成酵素-1の保護的役割2017

    • Author(s)
      関谷広樹、鈴木沙織、京極美帆、倉本大輔、市川尊文、北里英郎、小島史章
    • Organizer
      北里大学バイオサイエンスフォーラム
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 炎症性腸疾患における膜型プロスタグランジンE合成酵素-1の役割2017

    • Author(s)
      関谷広樹、河喜多智美、鈴木沙織、京極美帆、倉本大輔、市川尊文、北里英郎、小島史章
    • Organizer
      薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17K08604
  • [Presentation] 非アルコール性脂肪性肝炎におけるプロスタグランジン I2の役割解明2015

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木 仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場 (愛知県 名古屋市)
    • Year and Date
      2015-03-18
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] タバコ煙抽出液は血小板凝集を抑制する2015

    • Author(s)
      柏木仁、結城幸一、小島史章、粂井志麻、成宮周、牛首文隆
    • Organizer
      第88回日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場 (愛知県 名古屋市)
    • Year and Date
      2015-03-20
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 非アルコール性脂肪性肝炎におけるプロスタノイドの役割解明2014

    • Author(s)
      結城幸一、粂井志麻、柏木 仁、小島史章、成宮 周、牛首文隆
    • Organizer
      第65回日本薬理学会北部会
    • Place of Presentation
      コラッセふくしま (福島県 福島市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] Protective effect of the postaglandin I2-IP signal through the suppression of cytokines expression in nonalcoholic steatohepatitis.2014

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Fumitaka Ushikubi
    • Organizer
      Digestive Disease Week (DDW) 2014
    • Place of Presentation
      McCormick Place Convention Center (Chicago, IL)
    • Year and Date
      2014-05-03
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 炎症・免疫性疾患病態におけるプロスタノイド産生系・受容体シグナル系の役割2014

    • Author(s)
      小島史章
    • Organizer
      第5回 Okayama Young Investigator’s Seminar
    • Place of Presentation
      岡山大学 (岡山県 岡山市)
    • Year and Date
      2014-11-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] タバコ煙抽出液の血小板凝集抑制作用2014

    • Author(s)
      柏木仁、結城幸一、小島 史章、粂井志麻、牛首文隆
    • Organizer
      第65回日本薬理学会北部会
    • Place of Presentation
      コラッセふくしま (福島県 福島市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] シスプラチン誘発急性腎障害におけるプロスタグランジンE2受容体サブタイプEP1の役割2013

    • Author(s)
      小島史章
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22390045
  • [Presentation] プロスタグランジンI2の非アルコール性脂肪性肝炎の発症・進展における役割解明2012

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] トロンボキサンA2合成酵素の阻害は連用に伴うプロスタグランジンI2受容体アゴニストの作用減弱を抑制する2012

    • Author(s)
      柏木仁、結城幸一、小島史章、酒井芳紀、成宮周、牛首文隆
    • Organizer
      第85回日本薬理学会年会
    • Place of Presentation
      国立京都国際会館(京都)
    • Year and Date
      2012-03-14
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] 腎間質線維化におけるプロスタグランジンE2-EP4系の役割2011

    • Author(s)
      中川直樹、結城幸一、小島史章、柏木仁、藤野貴行、川辺淳一、長谷部直幸、牛首文隆
    • Organizer
      第63回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(仙台)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Facilitated progression of nonalcoholic steatohepatitis in mice lacking the prostaglandin I2 receptor2011

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Shuh Narumiya, Fumitaka Ushikubi
    • Organizer
      Keystone Symposia, Lipid Biology and Lipotoxicity
    • Place of Presentation
      INEC Killarney (Ireland)
    • Year and Date
      2011-05-17
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] トロンボキサンA2合成酵素の阻害はプロスタグランジンI2受容体の脱感作を抑制する2011

    • Author(s)
      柏木仁、結城幸一、小島史章、酒井芳紀、牛首文隆
    • Organizer
      第63回日本薬理学会北部会
    • Place of Presentation
      江陽グランドホテル(仙台)
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] プロスタグランジンI2の非アルコール性脂肪性肝炎の発症・進展における役割解明2011

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] 関節リウマチにおける膜型PGE合成酵素-1の役割2010

    • Author(s)
      小島史章
    • Organizer
      日本炎症・再生医学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Reduced T-cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice2010

    • Author(s)
      Rahul G. Matnani, Fumiaki Kojima, Jerold G. Woodward, Leslie J. Crofford
    • Organizer
      74th American College of Rheumatology (ACR) National Scientific Meeting
    • Place of Presentation
      Georgia World Congress Center (Georgia)
    • Year and Date
      2010-11-09
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] プロスタグランジンI2の非アルコール性脂肪性肝炎の発症・進展における役割解明2010

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木仁、奥村利勝、牛首文隆
    • Organizer
      第38回薬物活性シンポジウム・第20回日本循環薬理学会
    • Place of Presentation
      札幌市教育文化会館(北海道)
    • Year and Date
      2010-11-12
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Prostaglandin E_2 exacerbates ischemic brain injury via the EP_4 receptor subtype in mice subjected to a middle cerebral artery occlusion.2010

    • Author(s)
      Fumiaki Kojima
    • Organizer
      Keystone Symposia, Bioactive Lipids : Biochemistry and Diseases
    • Place of Presentation
      ウェスティン都ホテル京都(京都府)
    • Year and Date
      2010-06-09
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Prostaglandin E2 exacerbates ischemic brain injury via the EP4 receptor subtype in mice subjected to a middle cerebral artery occlusion2010

    • Author(s)
      Fumiaki Kojima, Akimasa Ri, Koh-ichi Yuhki, Yasuhiro Suzuki, Hitoshi Kashiwagi, Shuh Narumiya, Fumitaka Ushikubi
    • Organizer
      Keystone Symposia, Bioactive Lipids : Biochemistry and Diseases
    • Place of Presentation
      ウェスティン都ホテル京都(京都府)
    • Year and Date
      2010-06-09
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Prostaglandin E2 receptor subtype EP2 and EP4 emerge as novel targets for anti-platelet therapy2010

    • Author(s)
      Hitoshi Kashiwagi, Shuhko Kuriyama, Koh-ichi Yuhki, Fumiaki Kojima, Takayuki Maruyama, Shuh Narumiya, Fumitaka Ushikubi
    • Organizer
      Keystone Symposia, Bioactive Lipids: Biochemistry and Diseases
    • Place of Presentation
      ウェスティン都ホテル京都 (京都府)
    • Year and Date
      2010-06-08
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] プロスタグランジンE2受容体サブタイプEP4の抗血小板療法ターゲットとしての可能性2010

    • Author(s)
      柏木仁、栗山周子、結城幸一、小島史章、成宮周、牛首文隆
    • Organizer
      第38回薬物活性シンポジウム・第20回日本循環薬理学会
    • Place of Presentation
      札幌市教育文化会館(北海道)
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] 関節リウマチにおける膜型PGE合成酵素-の役割2010

    • Author(s)
      小島史章
    • Organizer
      第3回日本炎症・再生医学会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-08-05
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] 非アルコール性脂肪性肝炎の発症進展におけるプロスタグランジンI2の役割解明2010

    • Author(s)
      粂井志麻、結城幸一、柏木仁、小島史章、奥村利勝、牛首文隆
    • Organizer
      第61回日本薬理学会北部会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2010-09-10
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Prostaglandin E2 protects the heart from ischemia-reperfusion injury via its receptor subtype EP32010

    • Author(s)
      Koh-ichi Yuhki, Chun-Yang Xiao, Akiyoshi Hara, Hitoshi Kashiwagi, Fumiaki Kojima, Shuh Narumiya, Fumitaka Ushikubi
    • Organizer
      Keystone Symposia, Bioactive Lipids : Biochemistry and Diseases
    • Place of Presentation
      ウェスティン都ホテル京都(京都府)
    • Year and Date
      2010-06-09
    • Data Source
      KAKENHI-PROJECT-22700388
  • [Presentation] Protective effect of the postaglandin I2-IP signal through the suppression of cytokines expression in nonalcoholic steatohepatitis.

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Fumitaka Ushikubi.
    • Organizer
      Digestive Disease Week (DDW) 2014
    • Place of Presentation
      McCormick Place Convention Center (Chicago, IL)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 関節炎における膜型プロスタグランジンE2合成酵素-1の役割

    • Author(s)
      小島史章
    • Organizer
      第12回リウマチ膠原病 よつやセミナー
    • Place of Presentation
      京王プラザホテル(東京)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] Protective effect of the postaglandin I2-IP signal in MCD diet-induced nonalcoholic steatohepatitis in mice

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Shuh Narumiya, Fumitaka Ushikubi.
    • Organizer
      Digestive Disease Week (DDW) 2013
    • Place of Presentation
      Orange County Convention Center (Orlando, FL)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 非アルコール性脂肪性肝炎におけるプロスタグランジン I2 の役割解明

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木 仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      87回日本薬理学会年会
    • Place of Presentation
      東北大学百周年記念会館川内萩ホール、仙台国際センター(仙台)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 非アルコール性脂肪性肝炎の発症・進展におけるプロスタグランジンI2の役割解明

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木 仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      第64回日本薬理学会北部会
    • Place of Presentation
      朱鷺メッセ新潟コンベンションセンター(新潟)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] プロスタグランジンI2受容体アゴニストの連用に伴う血小板機能抑制作用の減弱はトロンボキサンA2合成酵素阻害薬の併用により回避できる

    • Author(s)
      柏木仁、結城幸一、小島史章、粂井志麻、酒井芳紀、成宮周、牛首文隆
    • Organizer
      第23回日本循環薬理学会
    • Place of Presentation
      福岡大学メディカルホール(福岡)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] Protective effect of the postaglandin I2-IP signal in MCD diet-induced nonalcoholic steatohepatitis in mice.

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Fumitaka Ushikubi.
    • Organizer
      Digestive Disease Week (DDW) 2013
    • Place of Presentation
      Orange County Convention Center (Orlando, FL)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] Roles of the prostaglandin I2-IP system in the development of nonalcoholic steatohepatitis.

    • Author(s)
      Shima Kumei, Koh-ichi Yuhki, Fumiaki Kojima, Hitoshi Kashiwagi, Toshikatsu Okumura, Shuh Narumiya, Fumitaka Ushikubi.
    • Organizer
      JST-CREST International Symposium. Frontiers in Immunology & I inflammation: From Molecules to Disease.
    • Place of Presentation
      一橋記念講堂(東京)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] トロンボキサンA2は連用に伴うプロスタグランジンI2受容体アゴニストであるベラプロストの抗血小板作用減弱において重要な役割を担う

    • Author(s)
      柏木仁、結城幸一、小島史章、粂井志麻、酒井芳紀、成宮周、牛首文隆
    • Organizer
      87回日本薬理学会年会
    • Place of Presentation
      東北大学百周年記念会館川内萩ホール、仙台国際センター(仙台)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] シスプラチン誘発急性腎障害におけるプロスタグランジンE2受容体サブタイプEP1の役割

    • Author(s)
      小島史章、結城幸一、柏木 仁、粂井志麻、成宮周、牛首文隆
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24790246
  • [Presentation] 非アルコール性脂肪性肝炎の発症・進展におけるプロスタグランジン I2 の役割解明

    • Author(s)
      粂井志麻、結城幸一、小島史章、柏木 仁、奥村利勝、成宮周、牛首文隆
    • Organizer
      第86回日本薬理学会年会
    • Place of Presentation
      福岡国際会議場(福岡)
    • Data Source
      KAKENHI-PROJECT-24790246
  • 1.  KASHIWAGI Hitoshi (60510609)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 2.  USHIKUBI Fumitaka (50243035)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  YUHKI Koh-ichi (80302420)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  Ishibashi Hitoshi (50311874)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  江藤 圭 (30545257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  秋田 久直 (70118777)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  市川 尊文 (30245378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 8.  内田 治仁 (00550857)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  坂本 信一 (70422235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  鍵谷 豪 (30524243)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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