• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Toda Munetoyo  戸田 宗豊

ORCIDConnect your ORCID iD *help
Researcher Number 30550727
Affiliation (Current) 2025: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授
2022: 京都府立医科大学, 医学(系)研究科(研究院), 准教授
2021 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 講師
2019 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教
2017 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 助教 … More
2015: 京都府立医科大学, 医学(系)研究科(研究院), 助教(特任講座)
2014: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教
2013: 京都府立医科大学, 医学(系)研究科(研究院), 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 56060:Ophthalmology-related / Ophthalmology
Except Principal Investigator
Basic Section 56060:Ophthalmology-related
Keywords
Principal Investigator
再生医療 / 角膜内皮細胞 / 移植・再生医療 / 細胞表面マーカー / エネルギー代謝 / 相転移 / 細胞相転移 / miRNA
Except Principal Investigator
角膜内皮細胞 / 細胞老化 … More / 角膜内皮 / リバーストランスレーショナルリサーチ / 再生医療 / NMN / ミトコンドリア / 微小環境 / メカノバイオロジー / 機能 / 角膜内皮疾患 / cilia / 培養細胞 / DSAEK / サル / ヒト / 細胞周期 / 一次繊毛 / Fuchs角膜内皮ジストロフィ / Bullous Keratopathy / Corneal Endothelial Cell / primary cilia Less
  • Research Projects

    (8 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (10 People)
  •  Elucidation of the mechanism of cellular degeneration by aqueous humor factors in cornea and trabecular meshwork

    • Principal Investigator
      山下 智子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A study of the adaptability of cultured human corneal endothelial cells to the post-transplant microenvironmentPrincipal Investigator

    • Principal Investigator
      戸田 宗豊
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A reverse translational research developed from cultured human corneal endothelial cell infusion therapy

    • Principal Investigator
      木下 茂
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Integral analysis of the cellular microenvironment aiming in vivo control of corneal endothelial cell fate

    • Principal Investigator
      上野 盛夫
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Establishment of a screening method for cultured human corneal endothelial cells maintaining long-term in vivo stability.Principal Investigator

    • Principal Investigator
      Toda Munetoyo
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Relationship between primary cilia and corneal endothelial disease in corneal endothelial cells and their function

    • Principal Investigator
      谷岡 秀敏
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Establishment of an in vivo cell differentiation method that induces an undifferentiated human corneal endothelial subpopulation to mature corneal endothelial cellsPrincipal Investigator

    • Principal Investigator
      Toda Munetoyo
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The development of a new way to regulate the cell state transition of cultured human corneal endothelial cells in regards to the possible RNA interference in infant corneasPrincipal Investigator

    • Principal Investigator
      Toda Munetoyo
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Kyoto Prefectural University of Medicine

All 2024 2023 2022 2020 2019 2016 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] Donor Corneal Endothelial Cell Maturity and Its Impact on Graft Survival in Glaucoma Patients Undergoing Corneal Transplantation2024

    • Author(s)
      Kitazawa Koji、Toda Munetoyo、Ueno Morio、Wakimasu Koichi、Tomioka Yasufumi、Uehara Asako、Sotozono Chie、Kinoshita Shigeru
    • Journal Title

      American Journal of Ophthalmology

      Volume: 262 Pages: 1-9

    • DOI

      10.1016/j.ajo.2024.01.033

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09725
  • [Journal Article] The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation2023

    • Author(s)
      Kitazawa Koji、Toda Munetoyo、Ueno Morio、Uehara Asako、Sotozono Chie、Kinoshita Shigeru
    • Journal Title

      Ophthalmology Science

      Volume: 3 Issue: 2 Pages: 100239-100239

    • DOI

      10.1016/j.xops.2022.100239

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09725, KAKENHI-PROJECT-21K09748
  • [Journal Article] Quiescent innate and adaptive immune responses maintain the long-term integrity of corneal endothelium reconstituted through allogeneic cell injection therapy2022

    • Author(s)
      Toda Munetoyo、Ueno Morio、Yamada Jun、Hiraga Asako、Asada Kazuko、Hamuro Junji、Sotozono Chie、Kinoshita Shigeru
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1

    • DOI

      10.1038/s41598-022-22522-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09725
  • [Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure2022

    • Author(s)
      UENO MORIO、TODA MUNETOYO、NUMA KOHSAKU、TANAKA HIROSHI、IMAI KOJIRO、BUSH JOHN、TERAMUKAI SATOSHI、OKUMURA NAOKI、KOIZUMI NORIKO、YAMAMOTO AKIHISA、TANAKA MOTOMU、SOTOZONO CHIE、HAMURO JUNJI、KINOSHITA SHIGERU
    • Journal Title

      American Journal of Ophthalmology

      Volume: 237 Pages: 267-277

    • DOI

      10.1016/j.ajo.2021.11.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00661, KAKENHI-PROJECT-20H01870, KAKENHI-PROJECT-21K09725, KAKENHI-PLANNED-19H05719
  • [Journal Article] Cellular Interplay Through Extracellular Vesicle miR-184 Alleviates Corneal Endothelium Degeneration2022

    • Author(s)
      Yamashita Tomoko、Asada Kazuko、Ueno Morio、Hiramoto Nao、Fujita Tomoko、Toda Munetoyo、Sotozono Chie、Kinoshita Shigeru、Hamuro Junji
    • Journal Title

      Ophthalmology Science

      Volume: 2 Issue: 4 Pages: 100212-100212

    • DOI

      10.1016/j.xops.2022.100212

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09725
  • [Journal Article] Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells2020

    • Author(s)
      Hamuro Junji、Numa Kohsaku、Fujita Tomoko、Toda Munetoyo、Ueda Koji、Tokuda Yuichi、Mukai Atushi、Nakano Masakazu、Ueno Morio、Kinoshita Shigeru、Sotozono Chie
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 61 Issue: 2 Pages: 10-10

    • DOI

      10.1167/iovs.61.2.10

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K11461, KAKENHI-PROJECT-18K16962
  • [Journal Article] In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots2019

    • Author(s)
      Toda Munetoyo、Yukawa Hiroshi、Yamada Jun、Ueno Morio、Kinoshita Shigeru、Baba Yoshinobu、Hamuro Junji
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 60 Issue: 12 Pages: 4008-4020

    • DOI

      10.1167/iovs.19-27788

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-17H02731, KAKENHI-PROJECT-17K10529, KAKENHI-PROJECT-17K11461
  • [Presentation] ミトコンドリア標的薬による培養ヒト角膜内皮細胞に対するミトコンドリア機能向上効果2024

    • Author(s)
      山下智子、戸田宗豊、木下茂
    • Organizer
      第128回 日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-23K27753
  • [Presentation] ヒト角膜内皮細胞の培養下における健常性を規定する因子の探索2024

    • Author(s)
      戸田宗豊、山下智子、北澤耕司、外園千絵、木下茂
    • Organizer
      第128回 日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09725
  • [Presentation] The maturity of donor corneal endothelial cell influences graft survival.2023

    • Author(s)
      7.Kitazawa K, Toda M, Ueno M, Uehara A, Sotozono C, Kinoshita S.
    • Organizer
      The 16th Korea-China-Japan Ophthalmologist
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K27753
  • [Presentation] ドナー角膜内皮細胞の健常性に影響を及ぼす要因の探索2019

    • Author(s)
      戸田宗豊、丸山悠子、上原朝子、北澤耕司、上野盛夫、羽室淳爾、外園千恵、木下茂
    • Organizer
      第123回 日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11461
  • [Presentation] 量子ドット標識ナノ技術による前房内注入培養ヒト角膜内皮細胞の生体内動態の解析2019

    • Author(s)
      戸田宗豊、湯川博、山田潤、上野盛夫、有本知子、外園千恵、馬場嘉信、木下茂、羽室淳爾
    • Organizer
      角膜カンファランス 2019
    • Data Source
      KAKENHI-PROJECT-17K11461
  • [Presentation] Factors influencing the health and longevity of donor corneal endothelial cells2019

    • Author(s)
      Munetoyo Toda, Koji Kitazawa, Morio Ueno, Yuko Maruyama, Asako Uehara, Chie Sotozono, Junji Hamuro, and Shigeru Kinoshita
    • Organizer
      Annual meeting of ARVO 2019
    • Data Source
      KAKENHI-PROJECT-17K11461
  • [Presentation] Metabolic plastisity in the cell-state homeostasis and differentiation of cultured human corneal endothelial cells.2016

    • Author(s)
      J. Hamuro, M. Ueno, K. Asada, M. Toda, M. Montoya, C. Sotozono, S. Kinoshita
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients.2016

    • Author(s)
      M. Ueno, M. Toda, A. Hiraga, K. Wakimasu, N. Koizumi, N. Okumura, K. Asada, C. Sotozono, J. Hamuro, S. Kinoshita
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] The role of dysregulated expression of miRs in the pathogenesis of bullous keratopathy and Fuchs' endothelial corneal dystrophy.2016

    • Author(s)
      K. Asada, M. Ueno, M. Toda, A. Hiraga, M. Montoya, C. Sotozono, S. Kinoshita, J. Hamuro
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Regulation of Mitochondrial respiration under cell culture stress in human corneal endothelial cells.2016

    • Author(s)
      S. Kinoshita, M. Ueno, K. Asada, M. Toda, K. Nagata, C. Sotozono, N. Kosaka, T. Ochiya, J. Hamuro
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] 角膜内皮細胞機能不全におけるepigeneticな細胞機能制御2016

    • Author(s)
      浅田和子、上野盛夫、戸田宗豊、平賀朝子、落谷孝広、外園千恵、木下茂、羽室淳爾
    • Organizer
      第120回 日本眼科学会総会
    • Place of Presentation
      仙台国際センター・東北大学百周年記念会館(宮城県仙台市)
    • Year and Date
      2016-04-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] 水疱性角膜症患者の血清中および前房水中サイトカインプロファイルの検討2016

    • Author(s)
      上野盛夫、戸田宗豊、平賀朝子、小泉範子、奥村直毅、浅田和子、外園千恵、羽室淳爾、木下茂
    • Organizer
      第120回 日本眼科学会総会
    • Place of Presentation
      仙台国際センター・東北大学百周年記念会館(宮城県仙台市)
    • Year and Date
      2016-04-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Quantifying the adhesion strength of human corneal endothelial cells in an in vitro model.2016

    • Author(s)
      H. Tanaka, A. Yamamoto, M. Toda, J. Hamuro, C. Sotozono, S. Kinoshita, M. Ueno, M. Tanaka
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] MiRNA profiles qualify epigenetic features of human corneal endothelial cells2016

    • Author(s)
      羽室淳爾、上野盛夫、浅田和子、戸田宗豊、外園千恵、木下茂
    • Organizer
      第120回 日本眼科学会総会
    • Place of Presentation
      仙台国際センター・東北大学百周年記念会館(宮城県仙台市)
    • Year and Date
      2016-04-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Allogeneic sensitization and tolerance induction post corneal endothelial cell injection into the anterior chamber.2016

    • Author(s)
      J. Yamada, M. Ueno, M. Toda, K. Shinomiya, C. Sotozono, S. Kinoshita, J. Hamuro
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] The cell homogeneity is indispensible for regenerative medicine by cultivated human corneal endothelial cells.2016

    • Author(s)
      M. Toda, M. Ueno, A. Hiraga, K. Asada, M. Montoya, C. Sotozono, J. Hamuro, S. Kinoshita
    • Organizer
      ARVO 2016 Annual Meeting
    • Place of Presentation
      Seattle (WA, U.S.A.)
    • Year and Date
      2016-05-01
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] 培養ヒト角膜内皮細胞亜集団の特性解析2016

    • Author(s)
      戸田宗豊、上野盛夫、平賀朝子、浅田和子、外園千恵、木下茂、羽室淳爾
    • Organizer
      第120回 日本眼科学会総会
    • Place of Presentation
      仙台国際センター・東北大学百周年記念会館(宮城県仙台市)
    • Year and Date
      2016-04-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Identification of differentiated mature cultured human corneal endothelial cells and their distinct cell propensity from other immature subpopulations2014

    • Author(s)
      M. Toda, M. Ueno, K. Ujihara, K. Asada, T. Nakamura, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Orlando. FL. U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] The integral analysis of senescence-associated secretory pathway and microRNA secretion of cultured human corneal endothelial cells relating to their functions, cell senescence, and epithelial-mesenchymal transition2014

    • Author(s)
      M. Ueno, K. Asada, M. Toda, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Orlando. FL. U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Distinct energy metabolism between cultured mature human corneal endothelial cells and their phenotype transitioned cells2014

    • Author(s)
      K. Asada, M. Toda, M. Ueno, K. Ujihara, A. Mukai, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Orlando. FL. U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] The integral analysis of gene signatures and miRNA expression of cultured human endothelial cells relating to their functions, cell senescence , epithelial mesenchymal transition and fibrosis2013

    • Author(s)
      K. Asada, M. Toda, M. Hagiya, K. Nakata, M. Ueno, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2013 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Seattle. WA. U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments2013

    • Author(s)
      M. Toda, K. Nakata, K. Asada, M. Hagiya, M. Ueno, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2013 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Seattle. WA. U.S.A.
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] nvestigation of the donor tissue information on the phenotypes of cultivated human corneal endothelium.

    • Author(s)
      H. Tanaka, M. Ueno, M. Toda, J. Hamuro, K. Yoshii, N. Koizumi, N. Okumura, S. Kinoshita, M. Montoya, B. Iliakis
    • Organizer
      2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Denver. CO. U.S.A.
    • Year and Date
      2015-05-03 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] The different binding properties of cultured human corneal endothelial cell subpopulations to Descemet’s membrane components.

    • Author(s)
      M. Toda, M. Ueno, A. Hiraga, K. Asada, T. Nakamura, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
    • Organizer
      2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Denver. CO. U.S.A.
    • Year and Date
      2015-05-03 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • [Presentation] Analysis of cytokines in serum and aqueous humor in patients with bullous keratopath.

    • Author(s)
      M. Ueno, M. Toda, A. Hiraga, N. Tobita, H. Nakagawa, C. Sotozono, N. Koizumi, K. Asada, J. Hamuro, S. Kinoshita
    • Organizer
      2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
    • Place of Presentation
      Denver. CO. U.S.A.
    • Year and Date
      2015-05-03 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-25670736
  • 1.  上野 盛夫 (40426531)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  山下 智子 (70470250)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  外園 千恵 (30216585)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  木下 茂 (30116024)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  HAMURO JUNJI (80536095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 19 results
  • 6.  谷岡 秀敏 (90171834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  北澤 耕司 (10760803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  田中 求 (00706814)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  UEDA Koji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  馬場 嘉信
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi