Toda Munetoyo 戸田宗豊

Researcher Number	30550727
Affiliation (Current)	2023: 京都府立医科大学, 医学(系)研究科(研究院), 特任准教授
Affiliation (based on the past Project Information) *help	2023: 京都府立医科大学, 医学(系)研究科(研究院), 准教授 2021 – 2022: 京都府立医科大学, 医学(系)研究科(研究院), 講師 2019 – 2020: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 2017 – 2018: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2015: 京都府立医科大学, 医学(系)研究科(研究院), 助教(特任講座) 2014: 京都府立医科大学, 医学(系)研究科(研究院), 特任助教 2013: 京都府立医科大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 再生医療 / 角膜内皮細胞 / 移植・再生医療 / 細胞表面マーカー / エネルギー代謝 / 相転移 / 細胞相転移 / miRNA Except Principal Investigator 角膜内皮 / リバーストランスレーショナルリサーチ … More / 細胞老化 / 再生医療 / 微小環境 / メカノバイオロジー / 機能 / 角膜内皮疾患 / 角膜内皮細胞 / cilia / 培養細胞 / DSAEK / 一次繊毛 / サル / ヒト / 細胞周期 / primary cilia Less

Reverse translarional research based on cultured human corneal endothelial cell injection therapy
- Principal Investigator
  
  木下茂
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Integral analysis of the cellular microenvironment aiming in vivo control of corneal endothelial cell fate
- Principal Investigator
  
  上野盛夫
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of a screening method for cultured human corneal endothelial cells maintaining long-term in vivo stability.Principal Investigator
- Principal Investigator
  
  戸田宗豊
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Relationship between primary cilia and corneal endothelial disease in corneal endothelial cells and their function
- Principal Investigator
  
  谷岡秀敏
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Establishment of an in vivo cell differentiation method that induces an undifferentiated human corneal endothelial subpopulation to mature corneal endothelial cellsPrincipal Investigator
- Principal Investigator
  
  Toda Munetoyo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine
The development of a new way to regulate the cell state transition of cultured human corneal endothelial cells in regards to the possible RNA interference in infant corneasPrincipal Investigator
- Principal Investigator
  
  Toda Munetoyo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2022 2020 2019 2016 2014 2013 Other

All Journal Article Presentation

[Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure2022
- Author(s)
  UENO MORIO、TODA MUNETOYO、NUMA KOHSAKU、TANAKA HIROSHI、IMAI KOJIRO、BUSH JOHN、TERAMUKAI SATOSHI、OKUMURA NAOKI、KOIZUMI NORIKO、YAMAMOTO AKIHISA、TANAKA MOTOMU、SOTOZONO CHIE、HAMURO JUNJI、KINOSHITA SHIGERU
- Journal Title
  
  American Journal of Ophthalmology
  
  Volume: 237 Pages: 267-277
- DOI
  10.1016/j.ajo.2021.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00661, KAKENHI-PROJECT-20H01870, KAKENHI-PROJECT-21K09725
[Journal Article] Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells2020
- Author(s)
  Hamuro Junji、Numa Kohsaku、Fujita Tomoko、Toda Munetoyo、Ueda Koji、Tokuda Yuichi、Mukai Atushi、Nakano Masakazu、Ueno Morio、Kinoshita Shigeru、Sotozono Chie
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 61 Issue: 2 Pages: 10-10
- DOI
  10.1167/iovs.61.2.10
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0116, KAKENHI-PROJECT-17K11461, KAKENHI-PROJECT-18K16962
[Journal Article] In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots2019
- Author(s)
  Toda Munetoyo、Yukawa Hiroshi、Yamada Jun、Ueno Morio、Kinoshita Shigeru、Baba Yoshinobu、Hamuro Junji
- Journal Title
  
  Investigative Opthalmology & Visual Science
  
  Volume: 60 Issue: 12 Pages: 4008-4020
- DOI
  10.1167/iovs.19-27788
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06354, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-17H02731, KAKENHI-PROJECT-17K10529, KAKENHI-PROJECT-17K11461
[Presentation] ドナー角膜内皮細胞の健常性に影響を及ぼす要因の探索2019
- Author(s)
  戸田宗豊、丸山悠子、上原朝子、北澤耕司、上野盛夫、羽室淳爾、外園千恵、木下茂
- Organizer
  第123回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-17K11461
[Presentation] 量子ドット標識ナノ技術による前房内注入培養ヒト角膜内皮細胞の生体内動態の解析2019
- Author(s)
  戸田宗豊、湯川博、山田潤、上野盛夫、有本知子、外園千恵、馬場嘉信、木下茂、羽室淳爾
- Organizer
  角膜カンファランス 2019
- Data Source
  KAKENHI-PROJECT-17K11461
[Presentation] Factors influencing the health and longevity of donor corneal endothelial cells2019
- Author(s)
  Munetoyo Toda, Koji Kitazawa, Morio Ueno, Yuko Maruyama, Asako Uehara, Chie Sotozono, Junji Hamuro, and Shigeru Kinoshita
- Organizer
  Annual meeting of ARVO 2019
- Data Source
  KAKENHI-PROJECT-17K11461
[Presentation] Metabolic plastisity in the cell-state homeostasis and differentiation of cultured human corneal endothelial cells.2016
- Author(s)
  J. Hamuro, M. Ueno, K. Asada, M. Toda, M. Montoya, C. Sotozono, S. Kinoshita
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients.2016
- Author(s)
  M. Ueno, M. Toda, A. Hiraga, K. Wakimasu, N. Koizumi, N. Okumura, K. Asada, C. Sotozono, J. Hamuro, S. Kinoshita
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] The role of dysregulated expression of miRs in the pathogenesis of bullous keratopathy and Fuchs' endothelial corneal dystrophy.2016
- Author(s)
  K. Asada, M. Ueno, M. Toda, A. Hiraga, M. Montoya, C. Sotozono, S. Kinoshita, J. Hamuro
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Regulation of Mitochondrial respiration under cell culture stress in human corneal endothelial cells.2016
- Author(s)
  S. Kinoshita, M. Ueno, K. Asada, M. Toda, K. Nagata, C. Sotozono, N. Kosaka, T. Ochiya, J. Hamuro
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] 角膜内皮細胞機能不全におけるepigeneticな細胞機能制御2016
- Author(s)
  浅田和子、上野盛夫、戸田宗豊、平賀朝子、落谷孝広、外園千恵、木下茂、羽室淳爾
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター・東北大学百周年記念会館（宮城県仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] 水疱性角膜症患者の血清中および前房水中サイトカインプロファイルの検討2016
- Author(s)
  上野盛夫、戸田宗豊、平賀朝子、小泉範子、奥村直毅、浅田和子、外園千恵、羽室淳爾、木下茂
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター・東北大学百周年記念会館（宮城県仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Quantifying the adhesion strength of human corneal endothelial cells in an in vitro model.2016
- Author(s)
  H. Tanaka, A. Yamamoto, M. Toda, J. Hamuro, C. Sotozono, S. Kinoshita, M. Ueno, M. Tanaka
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] MiRNA profiles qualify epigenetic features of human corneal endothelial cells2016
- Author(s)
  羽室淳爾、上野盛夫、浅田和子、戸田宗豊、外園千恵、木下茂
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター・東北大学百周年記念会館（宮城県仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Allogeneic sensitization and tolerance induction post corneal endothelial cell injection into the anterior chamber.2016
- Author(s)
  J. Yamada, M. Ueno, M. Toda, K. Shinomiya, C. Sotozono, S. Kinoshita, J. Hamuro
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] The cell homogeneity is indispensible for regenerative medicine by cultivated human corneal endothelial cells.2016
- Author(s)
  M. Toda, M. Ueno, A. Hiraga, K. Asada, M. Montoya, C. Sotozono, J. Hamuro, S. Kinoshita
- Organizer
  ARVO 2016 Annual Meeting
- Place of Presentation
  Seattle (WA, U.S.A.)
- Year and Date
  2016-05-01
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] 培養ヒト角膜内皮細胞亜集団の特性解析2016
- Author(s)
  戸田宗豊、上野盛夫、平賀朝子、浅田和子、外園千恵、木下茂、羽室淳爾
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台国際センター・東北大学百周年記念会館（宮城県仙台市）
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Identification of differentiated mature cultured human corneal endothelial cells and their distinct cell propensity from other immature subpopulations2014
- Author(s)
  M. Toda, M. Ueno, K. Ujihara, K. Asada, T. Nakamura, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Orlando. FL. U.S.A.
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] The integral analysis of senescence-associated secretory pathway and microRNA secretion of cultured human corneal endothelial cells relating to their functions, cell senescence, and epithelial-mesenchymal transition2014
- Author(s)
  M. Ueno, K. Asada, M. Toda, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Orlando. FL. U.S.A.
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Distinct energy metabolism between cultured mature human corneal endothelial cells and their phenotype transitioned cells2014
- Author(s)
  K. Asada, M. Toda, M. Ueno, K. Ujihara, A. Mukai, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2014 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Orlando. FL. U.S.A.
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] The integral analysis of gene signatures and miRNA expression of cultured human endothelial cells relating to their functions, cell senescence , epithelial mesenchymal transition and fibrosis2013
- Author(s)
  K. Asada, M. Toda, M. Hagiya, K. Nakata, M. Ueno, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2013 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Seattle. WA. U.S.A.
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Proliferation Propensity of Cultured Human Corneal Endothelial Cells and Their Plasticity Dictated by Culture Microenvironments2013
- Author(s)
  M. Toda, K. Nakata, K. Asada, M. Hagiya, M. Ueno, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2013 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Seattle. WA. U.S.A.
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] nvestigation of the donor tissue information on the phenotypes of cultivated human corneal endothelium.
- Author(s)
  H. Tanaka, M. Ueno, M. Toda, J. Hamuro, K. Yoshii, N. Koizumi, N. Okumura, S. Kinoshita, M. Montoya, B. Iliakis
- Organizer
  2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Denver. CO. U.S.A.
- Year and Date
  2015-05-03 – 2015-05-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] The different binding properties of cultured human corneal endothelial cell subpopulations to Descemet’s membrane components.
- Author(s)
  M. Toda, M. Ueno, A. Hiraga, K. Asada, T. Nakamura, M. Hagiya, N. Okumura, N. Koizumi, J. Hamuro, S. Kinoshita
- Organizer
  2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Denver. CO. U.S.A.
- Year and Date
  2015-05-03 – 2015-05-07
- Data Source
  KAKENHI-PROJECT-25670736
[Presentation] Analysis of cytokines in serum and aqueous humor in patients with bullous keratopath.
- Author(s)
  M. Ueno, M. Toda, A. Hiraga, N. Tobita, H. Nakagawa, C. Sotozono, N. Koizumi, K. Asada, J. Hamuro, S. Kinoshita
- Organizer
  2015 Annual Meeting of the ARVO (Association for Research in Vision and Ophthalmology)
- Place of Presentation
  Denver. CO. U.S.A.
- Year and Date
  2015-05-03 – 2015-05-07
- Data Source
  KAKENHI-PROJECT-25670736

1. 上野盛夫 (40426531)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. 外園千恵 (30216585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HAMURO JUNJI (80536095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
4. 谷岡秀敏 (90171834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山下智子 (70470250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 木下茂 (30116024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中求 (00706814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 北澤耕司 (10760803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDA Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 馬場嘉信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Toda Munetoyo 戸田 宗豊

Research Projects

Research Products

Co-Researchers

Reverse translarional research based on cultured human corneal endothelial cell injection therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Integral analysis of the cellular microenvironment aiming in vivo control of corneal endothelial cell fate

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a screening method for cultured human corneal endothelial cells maintaining long-term in vivo stability.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Relationship between primary cilia and corneal endothelial disease in corneal endothelial cells and their function

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of an in vivo cell differentiation method that induces an undifferentiated human corneal endothelial subpopulation to mature corneal endothelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The development of a new way to regulate the cell state transition of cultured human corneal endothelial cells in regards to the possible RNA interference in infant corneasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Superiority of Mature Differentiated Cultured Human Corneal Endothelial Cell Injection Therapy for Corneal Endothelial Failure2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolites Interrogation in Cell Fate Decision of Cultured Human Corneal Endothelial Cells2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In Vivo Fluorescence Visualization of Anterior Chamber Injected Human Corneal Endothelial Cells Labeled With Quantum Dots2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ドナー角膜内皮細胞の健常性に影響を及ぼす要因の探索2019

Author(s)

Organizer

Data Source

[Presentation] 量子ドット標識ナノ技術による前房内注入培養ヒト角膜内皮細胞の生体内動態の解析2019

Author(s)

Organizer

Data Source

[Presentation] Factors influencing the health and longevity of donor corneal endothelial cells2019

Author(s)

Organizer

Data Source

[Presentation] Metabolic plastisity in the cell-state homeostasis and differentiation of cultured human corneal endothelial cells.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Profiles of cytokines in the aqueous humor and serum of bullous keratopathy patients.2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] The role of dysregulated expression of miRs in the pathogenesis of bullous keratopathy and Fuchs' endothelial corneal dystrophy.2016

Toda Munetoyo 戸田宗豊