WAKITA Daiko 脇田大功

Researcher Number	30555404
Affiliation (based on the past Project Information) *help	2010 – 2012: 北海道大学, 遺伝子病制御研究所, 助教
Review Section/Research Field	Principal Investigator Carcinogenesis / Tumor immunology Except Principal Investigator Tumor immunology
Keywords	Principal Investigator 遺伝的背景 / 発癌 / 慢性炎症 / γδT細胞 / IL-17 / MDSC / 好中球 / マクロファージ / 腫瘍内微小環境 / IL-6 / MDSCs / 免疫抑制 … More Except Principal Investigator … More TGF-β / TGF-b / TGF-ss / CD133 / 腫瘍内微小環境 / IL-17 / 癌幹細胞 Less

癌微小環境におけるT細胞を介した炎症制御機構の解明Principal Investigator
- Principal Investigator
  
  脇田大功
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Carcinogenesis
- Research Institution
  Hokkaido University
Elucidation of protumor/antitumor immune regulation mechanisms based on host versus cancer stem cell responses
- Principal Investigator
  
  NISHIMURA Takashi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor immunology
- Research Institution
  Hokkaido University
Regulation of myeloid-derived suppressor cells in tumor microenvironmentPrincipal Investigator
- Principal Investigator
  
  WAKITA Daiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor immunology
- Research Institution
  Hokkaido University

All 2013 2012 2011 2010 Other

All Journal Article Presentation Book

[Book] ヘルパーT細胞を軸とした抗腫瘍免疫の制御:基盤研究から臨床応用まで」.シーエムシー出版がん免疫療法.実用化へのチャレンジ2010
- Author(s)
  西村孝司、脇田大功、大栗敬幸、北村秀光
- Data Source
  KAKENHI-PROJECT-22700894
[Book] がん免疫療法-実用化へのチャレンジ「ヘルパーT細胞を軸とした抗腫瘍免疫の制御:基盤研究から臨床応用まで」2010
- Author(s)
  西村孝司、脇田大功、大栗敬幸、北村秀光
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice2013
- Author(s)
  Narita Y, Kitamura H, Wakita D, Sumida K, Masuko K, Terada S, Nakano K, Nishimura T
- Journal Title
  
  J Immunol
  
  Volume: 190(2) Issue: 2 Pages: 812-20
- DOI
  10.4049/jimmunol.1103797
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] 革新的次世代癌ワクチン,helper/killer-hybrid epitope long peptide(H/K-HELP)の開発　基盤研究から臨床研究、そしてまた基盤研究へ2012
- Author(s)
  西村孝司、脇田大功、富樫裕二、北村秀光
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 57 Pages: 543-555
- NAID
  40019337455
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] First clinical trial of cancer vaccine therapy with artificially synthesized helper/killer-hybrid epitope long peptide ofMAGE-A4 cancer antigen2012
- Author(s)
  Takahashi N, Ohkuri T, Homma S, Ohtake J, Wakita D, Togashi Y, Kitamura H, Todo S, Nishimura T
- Journal Title
  
  Cancer Sci
  
  Volume: 103(1) Issue: 1 Pages: 150-3
- DOI
  10.1111/j.1349-7006.2011.02106.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331, KAKENHI-PROJECT-22700894, KAKENHI-PROJECT-22790370
[Journal Article] 巷間で行われるリンパ球移入療法の問題点2012
- Author(s)
  西村孝司、脇田大功、大栗敬幸、富樫裕二、北村秀光
- Journal Title
  
  メジカルビュー社
  
  Volume: Vol.27, No.12 Pages: 124-133
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] IFN-γ elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model2012
- Author(s)
  Kobayashi M, Ashino S, Shiohama Y, Wakita D, Kitamura H, Nishimura T
- Journal Title
  
  Eur J Immunol
  
  Volume: 42(2) Issue: 2 Pages: 393-402
- DOI
  10.1002/eji.201141845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331, KAKENHI-PROJECT-22700894, KAKENHI-PROJECT-22790370
[Journal Article] Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner2012
- Author(s)
  Koizumi S, Masuko K, Wakita D, Tanaka S, Mitamura R, Kato Y, Tabata H, Nakahara M, Kitamura H, Nishimura T
- Journal Title
  
  Cell Immunol
  
  Volume: 276(1-2) Issue: 1-2 Pages: 153-61
- DOI
  10.1016/j.cellimm.2012.05.002
- NAID
  120004710972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells2012
- Author(s)
  Yoshida T, Katsuya K, Oka T, Koizumi S, Wakita D, Kitamura H, Nishimura T
- Journal Title
  
  Biomed. Res.
  
  Volume: 33 Issue: 2 Pages: 67-74
- DOI
  10.2220/biomedres.33.67
- NAID
  130004470810
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] helper/killer-hybrid epitope long peptide(H/K-HELP)の開発基盤研究から臨床研究2012
- Author(s)
  西村孝司、脇田大功、富樫裕二、北村秀光
- Journal Title
  
  そしてまた基盤研究へ臨床免疫・アレルギー科
  
  Volume: 57(5) Pages: 543-555
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor2012
- Author(s)
  Kitamura H, Kobayashi M, Wakita D, Nishimura T
- Journal Title
  
  J Immunol
  
  Volume: 188(9) Issue: 9 Pages: 4200-8
- DOI
  10.4049/jimmunol.1102521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses2012
- Author(s)
  Sumida K, Wakita D, Narita Y, Masuko K, Terada S, Watanabe K, Satoh T, Kitamura H, Nishimura T
- Journal Title
  
  Eur J Immunol
  
  Volume: 42(8) Issue: 8 Pages: 2060-72
- DOI
  10.1002/eji.201142335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] The development of IL-17/IFN-γ-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter2012
- Author(s)
  Satoh T, Tajima M, Wakita D, Kitamura H, Nishimura T
- Journal Title
  
  Eur J Immunol
  
  Volume: 42(9) Issue: 9 Pages: 2329-42
- DOI
  10.1002/eji.201142240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Blockade of IL-6-signaling inhibits the pathogenesis of CD4(+) T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen2011
- Author(s)
  Noguchi D, Wakita D, Ohkuri T, Tajima M, Chamoto K, Kitamura H, Nishimura T.
- Journal Title
  
  Immunol Lett
  
  Volume: 136(2) Pages: 146-55
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21256159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 腫瘍微小環境由来TGF-ssによって誘導される腫瘍増殖促進免疫制御細胞群の性状とその克服によるがん免疫治療2011
- Author(s)
  西村孝司、脇田大功
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56(1) Pages: 7-17
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Phagocytosis of liposome particles by rat splenic immature monocytes makes them transiently and highly immunosuppressive in ex vivo culture conditions2011
- Author(s)
  Takahashi D, Nishimura T, et al.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 337 Issue: 1 Pages: 42-49
- DOI
  10.1124/jpet.110.172510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331, KAKENHI-PROJECT-22700894
[Journal Article] Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum Coronarium L2011
- Author(s)
  Tanaka S, Koizumi SI, Masuko K, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Ohkuri T, Wakita D, Chamoto K, Kitamura H, Nishimura T.
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11(2) Pages: 226-32
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21144920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity in duced by Chrysanthemum Coronarium L.2011
- Author(s)
  Sachi Tanaka, Daiko Wakita, et al.
- Journal Title
  
  International Immunopharmacology
  
  Volume: 11 Pages: 226-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L2011
- Author(s)
  Tanaka S, Koizumi S, Masuko K, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Ohkuri T, Wakita D, Chamoto K, Kitamura H, Nishimura T
- Journal Title
  
  Int Immunopharmacol
  
  Volume: 11(2) Issue: 2 Pages: 226-32
- DOI
  10.1016/j.intimp.2010.11.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Extract of Japanese soybean, Kurosengoku (Glycine max), activates Type-1 immunity via IL-12 production in a Toll-like receptor 2- and 4-dependent manner.2011
- Author(s)
  Sachi Tanaka, Daiko Wakita, et al.
- Journal Title
  
  Cellular Immunology
  
  Volume: 11 Pages: 226-232
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 腫瘍微小環境由来TGF-によって誘導される腫瘍増殖促進免疫制御細胞群の性状とその克服によるがん免疫治療2011
- Author(s)
  西村孝司、脇田大功
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56(1) Pages: 7-17
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Blockade of IL-6-signaling inhibits the pathogenesis of CD4(+) T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen.2011
- Author(s)
  Daisuke Noguchi, Daiko Wakita, et al.
- Journal Title
  
  Immunology Letters
  
  Volume: 136 Pages: 146-155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γ byDC or NK1.1(+) cells in a TLR4-andTLR2-dependent manner2011
- Author(s)
  Tanaka S, Koizumi S, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Wakita D, Chamoto K, Kitamura H, Nishimura T
- Journal Title
  
  Cell Immunol
  
  Volume: 266(2) Issue: 2 Pages: 135-42
- DOI
  10.1016/j.cellimm.2010.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] IL-17/IFN-γdouble producing CD8+T(Tc17/IFN-γ) cells : A novel cytotoxic T-cell subset converted from Tc17 cells by IL-122011
- Author(s)
  Tajima M, Wakita D, Satoh T, Kitamura H, Nishimura T.
- Journal Title
  
  Int Immunol
  
  Volume: 23(12) Pages: 751-9
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22039016(*equallycontributed)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] がん特異的な細胞治療の現状2011
- Author(s)
  西村孝司、脇田大功、富樫裕二、北村秀光
- Journal Title
  
  カレントテラピー
  
  Volume: 29(12) Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Phagocytosis of liposome particles by rat splenic immature monocytes makes them transiently and highly immunosuppressive2011
- Author(s)
  Takahashi D, Azuma H, Sakai H, Sou K, Wakita D, Abe H, Fujihara N, Horinouchi H, Nishimura T, Kobayashi K, Ikeda H.
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 337(1) Pages: 42-9
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/21212161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] The extract of Japanese soybean, Kurosengoku activates the production of IL-12 and IFN-γby DC or NK1. 1(+) cells in a TLR4-and TLR2-dependent manner2011
- Author(s)
  Tanaka S, Koizumi S, Makiuchi N, Aoyagi Y, Quivy E, Mitamura R, Kano T, Wakita D, Chamoto K, Kitamura H, Nishimura T.
- Journal Title
  
  Cell Immunol
  
  Volume: 266(2) Pages: 135-42
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20971456
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 腫瘍微小環境由来TGF-bによって誘導される腫瘍増殖促進免疫制御細胞群の性状とその克服によるがん免疫治療2011
- Author(s)
  西村孝司、脇田大功
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 56 Pages: 7-17
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] がん特異的な細胞治療の現状2011
- Author(s)
  西村孝司、脇田大功、富樫裕二、北村秀光
- Journal Title
  
  カレントテラピー
  
  Volume: 29(12) Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Blockade of IL-6-signaling inhibits the pathogenesis of CD4+ T cell-mediated lethal graft-versus-host reaction against minor histocompatibility antigen2011
- Author(s)
  Noguchi D, Wakita D, Ohkuri T, Tajima M, Chamoto K, Kitamura H, Nishimura T
- Journal Title
  
  Immunol Lett
  
  Volume: 136(2) Issue: 2 Pages: 146-55
- DOI
  10.1016/j.imlet.2011.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] IL-17/IFN-γ double producing CD8+T (Tc17/IFN-γ) cells : A novel cytotoxic T-cell subset converted from Tc17 cells by IL-122011
- Author(s)
  Masaki Tajima, et al
- Journal Title
  
  International Immunology
  
  Volume: 23 Issue: 12 Pages: 751-759
- DOI
  10.1093/intimm/dxr086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J03133, KAKENHI-PROJECT-22300331, KAKENHI-PROJECT-22700894, KAKENHI-PROJECT-22790370
[Journal Article] 1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells.2011
- Author(s)
  Utako Ikeda, Daiko Wakita, et al
- Journal Title
  
  Cellular Immunology
  
  Volume: 266 Pages: 135-142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] がん特異的な細胞治療の現状2011
- Author(s)
  西村孝司、脇田大功, 他
- Journal Title
  
  カレントテラピー
  
  Volume: 29 Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor by promoting angiogenesis2010
- Author(s)
  Wakita D, Sumida K, Iwakura Y, Nishikawa H, Ohkuri T, Chamoto K, Kitamura H, Nishimura T
- Journal Title
  
  Eur J Immunol
  
  Volume: 40(7) Issue: 7 Pages: 1927-37
- DOI
  10.1002/eji.200940157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor via promoting angiogenesis.2010
- Author(s)
  Daiko Wakita, et al.
- Journal Title
  
  Europian Journal of Immunology
  
  Volume: 40 Pages: 1927-1937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Th17細胞による気道過敏反応増強とその機序Th1/Th細胞依存的気道炎症との異同2010
- Author(s)
  西村孝司、脇田大功, 他
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54 Pages: 631-638
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor via promoting angiogenesis.2010
- Author(s)
  Daiko Wakita, Takashi Nishimura, et al.
- Journal Title
  
  Europian Journal of Immunology
  
  Volume: 40 Pages: 1927-1937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] 1α, 25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells2010
- Author(s)
  Ikeda U, Wakita D, Ohkuri T, Chamoto K, Kitamura H, Iwakura Y, Nishimura T.
- Journal Title
  
  Immunol Lett
  
  Volume: 134(1) Pages: 7-16
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20655952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 活性型ビタミンD_3とall-transレチノイン酸(ATRA)によるTh17細胞の分化制御とその疾病治療への応用2010
- Author(s)
  池田詩子、但馬正樹、芦野滋、脇田大功、北村秀光, 西村孝司
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 53(3) Pages: 247-259
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 1α,25-Dihydroxyvitamin D3 and all-transretinoic acid synergistically inhibit thedifferentiation and expansion of Th17 cells2010
- Author(s)
  Ikeda U, Wakita D, Ohkuri T, Chamoto K, Kitamura H, Iwakura Y, Nishimura T
- Journal Title
  
  Immunol Lett
  
  Volume: 134(1) Issue: 1 Pages: 7-16
- DOI
  10.1016/j.imlet.2010.07.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Tumor-infiltrating IL-17-producing gammadelta T cells support the progression of tumor via promoting angiogenesis2010
- Author(s)
  Wakita D, Sumida K, Iwakura Y, Nishikawa H, Ohkuri T, Chamoto K, Kitamura H, Nishimura T.
- Journal Title
  
  Eur J Immunol
  
  Volume: 40(7) Pages: 1927-37
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/20397212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] 巷間で行われるリンパ球移入療法の問題点2010
- Author(s)
  西村孝司、脇田大功、大栗敬幸、富樫裕二、北村秀光
- Journal Title
  
  月刊Mebio
  
  Volume: 27(12) Pages: 124-133
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] 巷間で行われるリンパ球移入療法の問題点2010
- Author(s)
  西村孝司、脇田大功, 他
- Journal Title
  
  月刊Mebio
  
  Volume: 27 Pages: 124-133
- Data Source
  KAKENHI-PROJECT-22700894
[Journal Article] Th17細胞による気道過敏反応増強とその機序Th1/Th細胞依存的気道炎症との異同2010
- Author(s)
  西村孝司、小林稔、脇田大功、北村秀光、芦野滋
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54(6) Pages: 631-638
- Data Source
  KAKENHI-PROJECT-22300331
[Journal Article] Th17細胞による気道過敏反応増強とその機序Th1/Th細胞依存的気道炎症との異同
- Author(s)
  西村孝司、脇田大功、小林稔、北村秀光、芦野滋
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 54(6) Pages: 631-638
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] CD133陽性癌幹細胞様細胞の免疫逃避能獲得における分子機構の解析2012
- Author(s)
  脇田大功, 他
- Organizer
  日本がん免疫学会
- Place of Presentation
  北海道大学学術交流会館
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-24501302
[Presentation] IL-17-producingγδT cells induce genetically controlled chronic inflammation and promote carcinoma development in BALB/c mouse skin2011
- Author(s)
  Daiko Wakita, Kentaro Sumida, Takayuki Satoh, Yoichiro Iwakura, Hiroyoshi Nishikawa, Hidemitsu Kitamura, Takashi Nishimura.
- Organizer
  The Joint International Meeting of The 76th Annual Meeting of the Japanese Society for Interferon and Cytokine Research, The 19th International Symposium of Macrophage Molecular and Cell Bilogy2011
- Place of Presentation
  全日空ゲートタワーホテル大阪
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] Cancer-associated inflammation mediated by IL-17-producing T cells and its genetic control(IL-17産生γδT細胞を介した炎症性発がん機構とその遺伝子支配)2011
- Author(s)
  脇田大功、角田健太郎、佐藤崇之、寺田聖、西川博嘉、岩倉洋一郎、北村秀光、西村孝司
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-17産生γδT細胞による慢性炎症の遺伝子支配と発がんへの関与/Genetic control of chronic inflammation mediated by IL-17-producingγδT cells during carcinogenesis2011
- Author(s)
  脇田大功、角田健太郎、佐藤崇之、寺田聖、岩倉洋一郎、西川博嘉、北村秀光、西村孝司
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-17産生γδT細胞による発癌促進機構2011
- Author(s)
  脇田大功
- Organizer
  第7回北海道癌免疫制御研究会
- Place of Presentation
  札幌パークホテル(北海道)(招待講演)
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] Genetic control of chronic inflammation mediated by IL-17-producing γδT cells during carcinogenesis2011
- Author(s)
  脇田大功, 他
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-17産生T細胞による発癌促進機構2011
- Author(s)
  脇田大功
- Organizer
  第7回北海道癌免疫制御研究会
- Place of Presentation
  札幌パークホテル
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] 慢性炎症微小環境におけるIL-17産生γδT細胞制御機構とその発がんへの関与2011
- Author(s)
  脇田大功, 他
- Organizer
  第15回日本がん免疫学会総会
- Place of Presentation
  千里ライフサイエンスセンター(大阪)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] 慢性炎症微小環境におけるIL-17産生γδT細胞制御機構とその発がんへの関与2011
- Author(s)
  脇田大功、角田健太郎、佐藤崇之、寺田聖、西川博嘉、岩倉洋一郎、北村秀光、西村孝司
- Organizer
  第15回日本がん免疫学会総会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] Caneer-associated inflammation mediated by IL-17-producing γδT cells and its genetic control2011
- Author(s)
  脇田大功, 他
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-17-producing γδT cells induce genetically controlled chronic inflammation and promote carcinoma development in BALB/c mouse skin2011
- Author(s)
  脇田大功, 他
- Organizer
  The Joint International Meeting of The 76th Annual Meeting of the Japanese Society for Interferon and Cytokine Research
- Place of Presentation
  全日空ゲートタワーホテル大阪(大阪)
- Year and Date
  2011-05-25
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] 発癌過程ほよび腫瘍増殖におけるIL-17産生細胞の意義とその遺伝子支配2010
- Author(s)
  脇田大功, 他
- Organizer
  第14回がん免疫学会総会
- Place of Presentation
  KKRホテル熊本(熊本県)
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] 発癌過程ほよび腫瘍増殖におけるIL-17産生細胞の意義とその遺伝子支配2010
- Author(s)
  脇田大功、角田健太郎、佐藤崇之、久保田那月、西川博嘉、岩倉洋一郎、大栗敬幸、北村秀光、西村孝司
- Organizer
  第14回がん免疫学会総会
- Place of Presentation
  KKRホテル熊本
- Year and Date
  2010-07-23
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-6依存的に異常増殖する担癌マウスimmature myeloid cellsの制御と癌治療への応用2010
- Author(s)
  脇田大功、角田健太郎、北村秀光、西村孝司
- Organizer
  第75回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] Genetic control of generation of IL-17-rpducing cells during carcinogenesis.(発癌過程におけるIL-17産生細胞制御の遺伝支配)2010
- Author(s)
  脇田大功、角田健太郎、佐藤崇之、久保田那月、西川博嘉、岩倉洋一郎、大栗敬幸、北村秀光、西村孝司
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  リーガロイヤルホテル大阪/大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] IL-6依存的に異常増殖する担癌マウスimmature myeloid cellsの制御と癌治療への応用2010
- Author(s)
  脇田大功, 他
- Organizer
  第75回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  北九州国際会議場(福岡県)
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] A crucial role for IL-17-producingγδT cells as a major tumor-promoting T cells at tumor microenvironments2010
- Author(s)
  D. Wakita, T. Nishimura
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] A crucial role for IL-17-producing γδ T cells as a major tumor-promoting T cells at tumor microenvironments2010
- Author(s)
  Daiko Wakita, et al.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22700894
[Presentation] Genetic control of generation of IL-17-rpducing cells during carcinogenesis.(発癌過程におけるIL-17産生細胞制御の遺伝支配)2010
- Author(s)
  脇田大功, 他
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  リーガロイヤルホテル大阪/大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22700894

1. KITAMURA Hidemitsu (40360531)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results
2. NISHIMURA Takashi (30143001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
3. 佐藤崇之 (00597924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WAKITA Daiko 脇田 大功

Research Projects

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Co-Researchers

癌微小環境におけるT細胞を介した炎症制御機構の解明Principal Investigator

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Elucidation of protumor/antitumor immune regulation mechanisms based on host versus cancer stem cell responses

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Regulation of myeloid-derived suppressor cells in tumor microenvironmentPrincipal Investigator

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[Book] ヘルパーT細胞を軸とした抗腫瘍免疫の制御:基盤研究から臨床応用まで」.シーエムシー出版がん免疫療法.実用化へのチャレンジ2010

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[Book] がん免疫療法-実用化へのチャレンジ「ヘルパーT細胞を軸とした抗腫瘍免疫の制御:基盤研究から臨床応用まで」2010

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[Journal Article] The key role of IL-6-arginase cascade for inducing dendritic cell-dependent CD4(+) T cell dysfunction in tumor-bearing mice2013

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[Journal Article] 革新的次世代癌ワクチン,helper/killer-hybrid epitope long peptide(H/K-HELP)の開発 基盤研究から臨床研究、そしてまた基盤研究へ2012

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NAID

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[Journal Article] First clinical trial of cancer vaccine therapy with artificially synthesized helper/killer-hybrid epitope long peptide ofMAGE-A4 cancer antigen2012

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[Journal Article] 巷間で行われるリンパ球移入療法の問題点2012

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[Journal Article] IFN-γ elevates airway hyper-responsiveness via up-regulation of neurokinin A/neurokinin-2 receptor signaling in a severe asthma model2012

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[Journal Article] Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner2012

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NAID

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[Journal Article] Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells2012

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[Journal Article] helper/killer-hybrid epitope long peptide(H/K-HELP)の開発基盤研究から臨床研究2012

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[Journal Article] Neuropeptide signaling activates dendritic cell-mediated type 1 immune responses through neurokinin-2 receptor2012

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[Journal Article] Anti-IL-6 receptor mAb eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T-cell responses2012

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WAKITA Daiko 脇田大功

[Journal Article] 革新的次世代癌ワクチン,helper/killer-hybrid epitope long peptide(H/K-HELP)の開発　基盤研究から臨床研究、そしてまた基盤研究へ2012