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Tachikawa Masashi  立川 正志

ORCIDConnect your ORCID iD *help
Researcher Number 30556882
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 理学部, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2025: 横浜市立大学, 理学部, 准教授
2020 – 2023: 国立研究開発法人理化学研究所, 数理創造プログラム, 客員研究員
2019 – 2021: 京都大学, ウイルス・再生医科学研究所, 准教授
2018: 国立研究開発法人理化学研究所, 数理創造プログラム, 客員研究員
2018: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員
2016 – 2017: 国立研究開発法人理化学研究所, 望月理論生物学研究室, 研究員
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (III) / Biological Sciences / Basic Section 43040:Biophysics-related
Except Principal Investigator
Broad Section G
Keywords
Principal Investigator
生物物理 / オルガネラ / 生物物理学 / パターン形成 / シミュレーション / 細胞形態 / ソフトマター / 分子動力学 / 機械学習 / 細胞・組織 / 細胞 … More
Except Principal Investigator
… More 染色体構築 / コンデンシン / 細胞分裂 / 染色体 / 数理生物学 / 生化学 / 細胞生物学 Less
  • Research Projects

    (9 results)
  • Research Products

    (44 results)
  • Co-Researchers

    (4 People)
  •  膜突出・陥入の力学とその細胞機能の理論解析Principal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Yokohama City University
  •  Toward theoretical descriptions of suparmolecular assemblies based on characteristics of molecular interactionsPrincipal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Yokohama City University
  •  力学モデルで理解する細胞集団の協同現象としての非細胞素材操作Principal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Yokohama City University
  •  非細胞素材を操作する職人細胞の形態力学モデルPrincipal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Yokohama City University
  •  数理モデリングを用いた選別輸送ゾーンのメカニズムの理解Principal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  ミトコンドリア・クリステ形態を構築するロジックPrincipal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Kyoto University
      Institute of Physical and Chemical Research
  •  オルガネラゾーン形成と成熟の数理モデリングPrincipal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Kyoto University
      Institute of Physical and Chemical Research
  •  Molecular mechanisms of condensins I and II

    • Principal Investigator
      Hirano Tatsuya
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section G
    • Research Institution
      Institute of Physical and Chemical Research
  •  細胞内環境が内膜系の3D形態を生み出すロジックPrincipal Investigator

    • Principal Investigator
      立川 正志
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

  • [Journal Article] Simulation study on “ torsion ” and local structure of chromosome: Loop structure via torsion-adding loop extrusion2024

    • Author(s)
      H. Yokota, and M. Tachikawa
    • Journal Title

      Journal of Advanced Simulation in Science and Engineering

      Volume: 11 Issue: 1 Pages: 54-72

    • DOI

      10.15748/jasse.11.54

    • ISSN
      2188-5303
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H05276, KAKENHI-PUBLICLY-23H04298, KAKENHI-PUBLICLY-23H04320
  • [Journal Article] Evaluation of loop formation dynamics in a chromatin fiber during chromosome condensation2022

    • Author(s)
      H. Yokota, and M. Tachikawa
    • Journal Title

      Prog. Theor. Exp. Phys.

      Volume: 2022 Issue: 5

    • DOI

      10.1093/ptep/ptac065

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Journal Article] Modeling Membrane Morphological Change during Autophagosome Formation2020

    • Author(s)
      Sakai Yuji、Koyama-Honda Ikuko、Tachikawa Masashi、Knorr Roland L.、Mizushima Noboru
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 101466-101466

    • DOI

      10.1016/j.isci.2020.101466

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06482, KAKENHI-PUBLICLY-20H04903
  • [Journal Article] Molecular dynamics simulations of condensin-mediated mitotic chromosome assembly2019

    • Author(s)
      Yuji Sakai, Tatsuya Hirano, Masashi Tachikawa
    • Journal Title

      Methods in Molecular Biology

      Volume: 2004 Pages: 319-334

    • DOI

      10.1007/978-1-4939-9520-2_22

    • ISBN
      9781493995196, 9781493995202
    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-18H04708, KAKENHI-PLANNED-15H05971, KAKENHI-PROJECT-18H05276
  • [Journal Article] Modeling the functions of condensin in chromosome shaping and segregation2018

    • Author(s)
      Sakai Yuji、Mochizuki Atsushi、Kinoshita Kazuhisa、Hirano Tatsuya、Tachikawa Masashi
    • Journal Title

      PLOS Computational Biology

      Volume: 14 Issue: 6 Pages: e1006152-e1006152

    • DOI

      10.1371/journal.pcbi.1006152

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04708, KAKENHI-PUBLICLY-18H04768, KAKENHI-PUBLICLY-18H04874, KAKENHI-PROJECT-15K06959
  • [Journal Article] Golgi apparatus self-organizes into the characteristic shape via postmitotic reassembly dynamics2017

    • Author(s)
      Tachikawa Masashi、Mochizuki Atsushi
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 114 Issue: 20 Pages: 5177-5182

    • DOI

      10.1073/pnas.1619264114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Journal Article] Measurement of caveolin-1 densities in the cell membrane for quantification of caveolar deformation after exposure to hypotonic membrane tension.2017

    • Author(s)
      Tachikawa M, Morone N, Senju Y, Sugiura T, Hanawa-Suetsugu K, Mochizuki A, Suetsugu S.
    • Journal Title

      Sci Rep.

      Volume: 7 Issue: 1 Pages: 1-14

    • DOI

      10.1038/s41598-017-08259-5

    • NAID

      120006818692

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07351, KAKENHI-PROJECT-17K19529, KAKENHI-PLANNED-15H05902, KAKENHI-PUBLICLY-16H01454, KAKENHI-PUBLICLY-17H06006
  • [Journal Article] Controlling segregation speed of entangled polymers by the shapes: A simple model for eukaryotic chromosome segregation2016

    • Author(s)
      Yuji Sakai, Masashi Tachikawa, and Atsushi Mochizuki
    • Journal Title

      Physical Review E

      Volume: 94 Issue: 4 Pages: 042403-042403

    • DOI

      10.1103/physreve.94.042403

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] ねじれの効果を考慮したループ押出しによる染色体の局所構造2024

    • Author(s)
      横田宏, 立川正志
    • Organizer
      第41回染色体ワークショップ
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Understanding chromosome condensation based on dynamical modes of twistable-polymer2023

    • Author(s)
      H. Yokota, M. Tachikawa, Y. Nishimura
    • Organizer
      The 4th Meeting on “Genome Modality”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Simulation study on “torsion” and local structure of chromosome: Loop structure via one side loop extrusion with twist deformation2023

    • Author(s)
      H. Yokota and M. Tachikawa
    • Organizer
      The 42nd JSST Annual International Conference on Simulation Technology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Self-organized formation of Golgi apparatus2022

    • Author(s)
      Masashi Tachikawa
    • Organizer
      RIKEN BDR Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H05781
  • [Presentation] Twist変形を伴う片側ループ押し出し機構によるループ構造のループ長さ依存性2022

    • Author(s)
      横田宏, 立川正志
    • Organizer
      ソフトバイオ研究会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Understanding chromosome condensation during mitotic phase through twist-bend coupling2022

    • Author(s)
      H. Yokota and M. Tachikawa
    • Organizer
      The 3rd Meeting on “Genome Modality”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] 熱的に駆動されるクロマチンループ生成の動力学とその妥当性2022

    • Author(s)
      横田宏, 立川正志
    • Organizer
      高分子物理学研究会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Physical model simulations for understanding the structures of organelles2022

    • Author(s)
      Masashi Tachikawa
    • Organizer
      5th NanoLSI Symposium
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04903
  • [Presentation] 熱的なクロマチンループ形成のダイナミクスとその妥当性2022

    • Author(s)
      横田宏, 立川正志
    • Organizer
      ゲノムモデリング研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] Physical model simulations for understanding the structures of organelles2022

    • Author(s)
      Masashi Tachikawa
    • Organizer
      5th NanoLSI Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H05781
  • [Presentation] Physical model simulations for understanding the structures of organelles2022

    • Author(s)
      M. Tachikawa
    • Organizer
      5th NanoLSI Symposium (Virtual)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] 生体膜の力学から オルガネラの形を理解する2022

    • Author(s)
      立川正志
    • Organizer
      第34回バイオエンジニアリング講演会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H05781
  • [Presentation] Self-organized Formation of Golgi Apparatus2022

    • Author(s)
      Masashi Tachikawa
    • Organizer
      RIKEN BDR Symposium 2022
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04903
  • [Presentation] Physical modeling for the self-organization of the Golgi apparatus morphology.2022

    • Author(s)
      Masashi Tachikawa
    • Organizer
      World Congress of Biomechanics 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H05781
  • [Presentation] Self-organized formation of Golgi apparatus2022

    • Author(s)
      M. Tachikawa
    • Organizer
      RIKEN BDR Symposium 2022 (Virtual)
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] 物理シミュレーションを用いて 細胞内膜形態を理解する試み2021

    • Author(s)
      立川正志
    • Organizer
      顕微鏡学会第77回学術講演会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H05781
  • [Presentation] 物理シミュレーションを用いて 細胞内膜形態を理解する試み2021

    • Author(s)
      立川正志
    • Organizer
      顕微鏡学会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-20H04903
  • [Presentation] 生体高分子におけるloop構造のエネルギー定量化のモデル2020

    • Author(s)
      横田宏, 立川正志
    • Organizer
      第75回日本物理学会年次大会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] A computational approach for understanding the Golgi morphology2019

    • Author(s)
      Masashi Tachikawa
    • Organizer
      第56回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04768
  • [Presentation] 生体高分子におけるloop構造のエネルギー定量化のモデル2019

    • Author(s)
      横田宏, 立川正志
    • Organizer
      第37回染色体ワークショップ・第18回核ダイナミクス研究会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] 生体高分子におけるloop構造のエネルギー定量化のモデル2019

    • Author(s)
      横田宏, 立川正志
    • Organizer
      第9回 高分子物理学研究会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] A computational approach for understanding the Golgi morphology2019

    • Author(s)
      Masashi Tachikawa
    • Organizer
      第56回日本生化学会大会
    • Data Source
      KAKENHI-PUBLICLY-18H04874
  • [Presentation] PHYSICAL MODELING OF FORMATION OF CELLULAR ORGANELLE2019

    • Author(s)
      Masashi Tachikawa
    • Organizer
      4th Africa International Biotechnology and Biomedical Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04874
  • [Presentation] PHYSICAL MODELING OF FORMATION OF CELLULAR ORGANELLE2019

    • Author(s)
      Masashi Tachikawa
    • Organizer
      4th Africa International Biotechnology and Biomedical Conference
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04768
  • [Presentation] 生体高分子におけるloop構造のエネルギー定量化のモデル2019

    • Author(s)
      横田宏, 立川正志
    • Organizer
      日本数理生物学会年会
    • Data Source
      KAKENHI-PROJECT-18H05276
  • [Presentation] ゴルジ装置の自己組織化形成過程2018

    • Author(s)
      立川 正志
    • Organizer
      第56回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04768
  • [Presentation] ゴルジ装置の自己組織化形成過程2018

    • Author(s)
      立川 正志
    • Organizer
      第56回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04874
  • [Presentation] In silico reconstitution of the Golgi reassembly process reveals the self-organizing properties2018

    • Author(s)
      立川 正志
    • Organizer
      FEBS Special Meeting. The 2018 Golgi Meeting: membrane trafficking in cell organization and homeostasis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04874
  • [Presentation] Physical modeling for shape and size regulations of mitochondria.2018

    • Author(s)
      立川 正志
    • Organizer
      第70回日本細胞生物学会
    • Data Source
      KAKENHI-PUBLICLY-18H04768
  • [Presentation] Physical Model Simulation of Golgi Reassembly Dynamics2018

    • Author(s)
      立川 正志
    • Organizer
      International Workshop on Biological Membranes
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04874
  • [Presentation] Biophysical simulation of Golgi formation process2018

    • Author(s)
      Masashi Tachikawa
    • Organizer
      International Workshop on Mathematical Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] 物理モデルから探るオルガネラの形とサイズ2017

    • Author(s)
      立川正志
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] Visualizing virtual Golgi dynamics by physical model simulation2017

    • Author(s)
      Masashi Tachikawa
    • Organizer
      EMBL Symposium “Seeing is Believing”
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] ゴルジ体再集合過程における層数制御機構2017

    • Author(s)
      立川正志
    • Organizer
      第69回日本細胞生物学会年会
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] Cargo accumulation can physically trigger membrane trafficking2016

    • Author(s)
      立川正志
    • Organizer
      The 2016 (26th) annual meeting of the Japanese Society for Mathematical Biology
    • Place of Presentation
      九州大学
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • [Presentation] Accumulation of cargo proteins can physically trigger vesiculation in membrane trafficking system2016

    • Author(s)
      立川正志
    • Organizer
      第54回日本生物物理学会年会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PUBLICLY-16H01454
  • 1.  Hirano Tatsuya (50212171)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  SUETSUGU Kyoko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  Suetsugu Shiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  境 祐二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results

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